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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxc8a

Z-value: 0.55

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Transcription factors associated with hoxc8a

Gene Symbol Gene ID Gene Info
hoxc8a
ENSDARG00000070346 homeobox C8a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc8adr11_v1_chr23_+_36101185_36101185-0.196.4e-02Click!

Activity profile of hoxc8a motif

Sorted Z-values of hoxc8a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_6188413 5.47 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr16_-_44945224 4.37 ENSDART00000156921
ncam3
neural cell adhesion molecule 3
chr13_+_13693722 4.18 ENSDART00000110509
si:ch211-194c3.5
si:ch211-194c3.5
chr8_+_31717175 3.56 ENSDART00000013434
oxct1a
3-oxoacid CoA transferase 1a
chr17_+_23298928 3.29 ENSDART00000153652
zgc:165461
zgc:165461
chr8_+_31716872 2.88 ENSDART00000161121
oxct1a
3-oxoacid CoA transferase 1a
chr2_-_33687214 2.76 ENSDART00000147439
atp6v0b
ATPase H+ transporting V0 subunit b
chr16_+_51180938 2.73 ENSDART00000169022
hmgn2
high mobility group nucleosomal binding domain 2
chr14_-_27121854 2.65 ENSDART00000173119
pcdh11
protocadherin 11
chr10_+_42358426 2.53 ENSDART00000025691
dbnla
drebrin-like a
chr8_+_22516728 2.45 ENSDART00000146013
si:ch211-261n11.3
si:ch211-261n11.3
chr15_-_15357178 2.39 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr8_+_18624658 2.33 ENSDART00000089141
fsd1
fibronectin type III and SPRY domain containing 1
chr2_+_31833997 2.30 ENSDART00000066788
epdr1
ependymin related 1
chr3_+_46628885 2.26 ENSDART00000006602
pde4a
phosphodiesterase 4A, cAMP-specific
chr1_+_52392511 2.21 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr2_+_50608099 2.19 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr18_+_924949 2.18 ENSDART00000170888
ENSDART00000193163
pkma
pyruvate kinase M1/2a
chr7_-_48667056 2.17 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr22_-_1079773 2.16 ENSDART00000136668
si:ch1073-15f12.3
si:ch1073-15f12.3
chr1_+_53842344 2.14 ENSDART00000114506
crfb17
cytokine receptor family member B17
chr3_+_22442445 2.13 ENSDART00000190921
wnk4b
WNK lysine deficient protein kinase 4b
chr18_+_7283283 2.10 ENSDART00000141493
ANO2 (1 of many)
si:ch73-86n2.1
chr8_-_31107537 2.09 ENSDART00000098925
vgll4l
vestigial like 4 like
chr8_+_52637507 2.00 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr3_-_31254379 1.93 ENSDART00000189376
apnl
actinoporin-like protein
chr11_+_11267493 1.89 ENSDART00000148425
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr2_-_16380283 1.87 ENSDART00000149992
si:dkey-231j24.3
si:dkey-231j24.3
chr21_+_30355767 1.81 ENSDART00000189948
CR749164.1

chr20_-_34750045 1.80 ENSDART00000186130
znf395b
zinc finger protein 395b
chr16_+_17389116 1.79 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr15_+_841383 1.78 ENSDART00000115077
zgc:174573
zgc:174573
chr20_+_40457599 1.74 ENSDART00000017553
serinc1
serine incorporator 1
chr4_+_76926059 1.72 ENSDART00000136192
si:dkey-240n22.6
si:dkey-240n22.6
chr1_-_58036509 1.65 ENSDART00000081122
COLGALT1
si:ch211-114l13.7
chr13_+_12299997 1.64 ENSDART00000108535
gabrb1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr20_-_7072487 1.63 ENSDART00000145954
si:ch211-121a2.2
si:ch211-121a2.2
chr17_+_26611929 1.63 ENSDART00000166450
ENSDART00000087023
ttc7b
tetratricopeptide repeat domain 7B
chr21_+_22738939 1.62 ENSDART00000151342
ENSDART00000079145
arhgap42a
Rho GTPase activating protein 42a
chr6_-_43283122 1.59 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr21_-_5856050 1.57 ENSDART00000115367
CABZ01071020.1

chr16_+_13818743 1.56 ENSDART00000090191
flcn
folliculin
chr15_-_43284021 1.53 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr18_+_27738349 1.51 ENSDART00000187816
tspan18b
tetraspanin 18b
chr13_-_35808904 1.50 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr11_+_37250839 1.46 ENSDART00000170209
il17rc
interleukin 17 receptor C
chr14_-_16082806 1.44 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr13_+_38521152 1.41 ENSDART00000145292
adgrb3
adhesion G protein-coupled receptor B3
chr6_-_30210378 1.37 ENSDART00000157359
ENSDART00000113924
lrrc7
leucine rich repeat containing 7
chr5_+_26213874 1.37 ENSDART00000193816
ENSDART00000098514
oclnb
occludin b
chr13_-_31812394 1.37 ENSDART00000124445
sertad4
SERTA domain containing 4
chr20_-_9462433 1.36 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr4_-_22472653 1.35 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
kmt2e
lysine (K)-specific methyltransferase 2E
chr6_-_40713183 1.34 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
si:ch211-157b11.12
chr4_-_815871 1.33 ENSDART00000067455
dpysl5b
dihydropyrimidinase-like 5b
chr21_-_35419486 1.33 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr20_-_45812144 1.31 ENSDART00000147897
ENSDART00000147637
fermt1
fermitin family member 1
chr15_+_15856178 1.31 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr14_-_47248784 1.30 ENSDART00000135479
fstl5
follistatin-like 5
chr2_+_20793982 1.26 ENSDART00000014785
prg4a
proteoglycan 4a
chr15_-_35252522 1.20 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr11_-_21528056 1.18 ENSDART00000181626
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr6_+_49723289 1.16 ENSDART00000190452
stx16
syntaxin 16
chr22_-_17474583 1.16 ENSDART00000148027
si:ch211-197g15.8
si:ch211-197g15.8
chr18_+_17827149 1.15 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr20_-_34750363 1.09 ENSDART00000152845
znf395b
zinc finger protein 395b
chr5_+_30635309 1.08 ENSDART00000183769
abcg4a
ATP-binding cassette, sub-family G (WHITE), member 4a
chr4_+_14727018 1.07 ENSDART00000124189
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr15_-_23420079 1.05 ENSDART00000104525
ENSDART00000148840
kmt2a
lysine (K)-specific methyltransferase 2A
chr7_-_30174882 1.05 ENSDART00000110409
frmd5
FERM domain containing 5
chr15_-_37104165 1.03 ENSDART00000165867
zmp:0000001114
zmp:0000001114
chr1_+_513986 1.02 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr3_-_34084387 0.97 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr4_+_5333988 0.97 ENSDART00000129398
ENSDART00000163850
ENSDART00000067374
ENSDART00000150780
ENSDART00000150493
ENSDART00000150306
apex1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr7_-_46777876 0.96 ENSDART00000193954
tshz3b
teashirt zinc finger homeobox 3b
chr24_+_36204028 0.94 ENSDART00000063832
ENSDART00000155260
rbbp8
retinoblastoma binding protein 8
chr8_-_7567815 0.94 ENSDART00000132536
hcfc1b
host cell factor C1b
chr22_+_29113796 0.90 ENSDART00000150264
pla2g6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr21_+_8427059 0.80 ENSDART00000143151
dennd1a
DENN/MADD domain containing 1A
chr21_-_32097908 0.80 ENSDART00000147387
si:ch211-160j14.3
si:ch211-160j14.3
chr10_-_35108683 0.80 ENSDART00000049633
zgc:110006
zgc:110006
chr13_+_36622100 0.79 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr15_+_29140126 0.78 ENSDART00000060034
zgc:113149
zgc:113149
chr11_-_40728380 0.76 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr23_-_29505645 0.75 ENSDART00000146458
kif1b
kinesin family member 1B
chr16_-_13623659 0.75 ENSDART00000168978
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr7_-_32895668 0.75 ENSDART00000141828
ano5b
anoctamin 5b
chr22_-_17474781 0.75 ENSDART00000186817
si:ch211-197g15.8
si:ch211-197g15.8
chr12_-_4532066 0.75 ENSDART00000092687
trpm4b.2
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr23_+_579893 0.71 ENSDART00000189098
BX323461.1

chr19_+_16064439 0.71 ENSDART00000151169
gmeb1
glucocorticoid modulatory element binding protein 1
chr19_-_33850201 0.70 ENSDART00000168583
otud6b
OTU domain containing 6B
chr19_-_205104 0.70 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr6_-_37744430 0.68 ENSDART00000150177
ENSDART00000149722
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr13_+_31070181 0.64 ENSDART00000110560
ENSDART00000146088
si:ch211-223a10.1
si:ch211-223a10.1
chr23_+_40604951 0.64 ENSDART00000114959
cdh24a
cadherin 24, type 2a
chr21_-_34032650 0.63 ENSDART00000138575
ENSDART00000047515
rnf145b
ring finger protein 145b
chr23_-_35790235 0.62 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
mfsd5
major facilitator superfamily domain containing 5
chr15_+_857148 0.62 ENSDART00000156949
si:dkey-7i4.13
si:dkey-7i4.13
chr24_+_22485710 0.61 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr13_+_31321297 0.61 ENSDART00000143308
antxr1d
anthrax toxin receptor 1d
chr4_+_14727212 0.61 ENSDART00000158094
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr25_-_7705487 0.61 ENSDART00000128099
prdm11
PR domain containing 11
chr13_+_35339182 0.59 ENSDART00000019323
jag1b
jagged 1b
chr16_-_13623928 0.58 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr11_+_30244356 0.57 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr4_-_46915962 0.55 ENSDART00000169555
si:ch211-134c10.1
si:ch211-134c10.1
chr16_-_28878080 0.55 ENSDART00000149501
si:dkey-239n17.4
si:dkey-239n17.4
chr6_+_18321627 0.54 ENSDART00000183107
ENSDART00000189715
card14
caspase recruitment domain family, member 14
chr16_+_4497302 0.53 ENSDART00000081826
ENSDART00000148096
ttc29
tetratricopeptide repeat domain 29
chr5_+_36768674 0.51 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr10_-_21955231 0.51 ENSDART00000183695
FO744833.2

chr24_+_26997798 0.49 ENSDART00000089506
larp4b
La ribonucleoprotein domain family, member 4B
chr20_-_27225876 0.49 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
si:dkey-85n7.7
chr10_+_15224660 0.48 ENSDART00000137932
sh3bp2
SH3-domain binding protein 2
chr3_+_30500968 0.48 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr21_+_29077509 0.48 ENSDART00000128561
ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr17_-_43556208 0.46 ENSDART00000188424
nt5c1ab
5'-nucleotidase, cytosolic IAb
chr13_-_46200240 0.46 ENSDART00000056984
ftr69
finTRIM family, member 69
chr20_-_29532939 0.44 ENSDART00000049224
ENSDART00000062377
taf1b
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr19_+_10592778 0.44 ENSDART00000135488
ENSDART00000151624
si:dkey-211g8.5
si:dkey-211g8.5
chr25_-_13490744 0.42 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr12_+_18744610 0.42 ENSDART00000153456
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr24_-_38657683 0.39 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr21_-_26490186 0.38 ENSDART00000009889
zgc:110540
zgc:110540
chr11_-_44979281 0.38 ENSDART00000190972
ldb1b
LIM-domain binding 1b
chrM_+_9052 0.37 ENSDART00000093612
mt-atp6
ATP synthase 6, mitochondrial
chr1_+_58628165 0.35 ENSDART00000158654
si:ch73-221f6.4
si:ch73-221f6.4
chr11_+_33818179 0.34 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr20_+_41021054 0.30 ENSDART00000146052
man1a1
mannosidase, alpha, class 1A, member 1
chr22_-_6229275 0.30 ENSDART00000146045
ENSDART00000179730
si:ch211-274k16.2
si:ch211-274k16.2
chr7_-_45999333 0.28 ENSDART00000158603
si:ch211-260e23.8
si:ch211-260e23.8
chr6_+_19948043 0.27 ENSDART00000182636
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr20_-_14925281 0.27 ENSDART00000152641
dnm3a
dynamin 3a
chr1_+_56755536 0.25 ENSDART00000157727
CABZ01049361.1

chr10_+_2899108 0.24 ENSDART00000147031
erap1a
endoplasmic reticulum aminopeptidase 1a
chr5_+_27137473 0.23 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr15_-_14552101 0.23 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr23_-_16485190 0.23 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr10_-_26744131 0.23 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr11_-_1509773 0.19 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr8_-_11004726 0.18 ENSDART00000192594
ENSDART00000020116
trim33
tripartite motif containing 33
chr15_+_31899312 0.17 ENSDART00000155315
frya
furry homolog a (Drosophila)
chr20_-_14924858 0.17 ENSDART00000047039
dnm3a
dynamin 3a
chr16_+_39159752 0.15 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr24_+_12894282 0.15 ENSDART00000061301
si:dkeyp-28d2.4
si:dkeyp-28d2.4
chr6_+_49722970 0.14 ENSDART00000155934
ENSDART00000154738
stx16
syntaxin 16
chr24_-_7321928 0.14 ENSDART00000167570
ENSDART00000045150
actr3b
ARP3 actin related protein 3 homolog B
chr20_+_11731039 0.11 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr10_+_11355841 0.10 ENSDART00000193067
ENSDART00000064215
cops4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr2_-_36500347 0.10 ENSDART00000110528
BX901889.1

chr11_+_45110865 0.08 ENSDART00000158188
mgea5l
meningioma expressed antigen 5 (hyaluronidase) like
chr15_-_42736433 0.06 ENSDART00000154379
si:ch211-181d7.1
si:ch211-181d7.1
chr17_-_43556415 0.05 ENSDART00000190102
ENSDART00000193156
nt5c1ab
5'-nucleotidase, cytosolic IAb
chr16_-_30903930 0.05 ENSDART00000143996
dennd3b
DENN/MADD domain containing 3b
chr4_+_22343093 0.05 ENSDART00000023588
guca1a
guanylate cyclase activator 1A
chr2_-_30668580 0.03 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr25_+_31868268 0.02 ENSDART00000022325
parp16
poly (ADP-ribose) polymerase family, member 16
chr3_+_7808459 0.02 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chrM_+_9735 0.01 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr8_-_30204650 0.00 ENSDART00000133209
zgc:162939
zgc:162939
chr2_+_16482338 0.00 ENSDART00000143912
fbxo36b
F-box protein 36b

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc8a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.4 GO:0046952 ketone body catabolic process(GO:0046952)
0.5 2.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.4 2.1 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.3 1.9 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.3 0.9 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.3 2.2 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 1.4 GO:0016322 neuron remodeling(GO:0016322)
0.3 0.8 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.3 0.8 GO:0002369 T cell cytokine production(GO:0002369)
0.2 1.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.2 1.6 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 1.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 1.1 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.1 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.1 5.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.3 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 2.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 1.7 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 0.4 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 1.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 0.8 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 1.1 GO:0033344 cholesterol efflux(GO:0033344)
0.0 1.0 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.5 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.0 3.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0060074 synapse maturation(GO:0060074)
0.0 2.2 GO:0006096 glycolytic process(GO:0006096)
0.0 2.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 7.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.6 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 1.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 2.6 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.9 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 4.2 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 1.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.5 GO:0045765 regulation of angiogenesis(GO:0045765)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0044218 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.2 2.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 2.5 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 2.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.6 GO:0044327 dendritic spine head(GO:0044327)
0.1 2.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.0 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.6 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 4.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 3.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.3 GO:0031201 SNARE complex(GO:0031201)
0.0 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.2 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.9 4.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 2.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 2.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 0.9 GO:0070336 flap-structured DNA binding(GO:0070336)
0.3 2.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 1.0 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 1.7 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.4 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 2.1 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 2.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 5.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 2.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 2.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 3.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.4 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 1.2 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.3 GO:0005178 integrin binding(GO:0005178)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.7 GO:0019838 growth factor binding(GO:0019838)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.8 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.3 GO:0005227 calcium activated cation channel activity(GO:0005227) ion gated channel activity(GO:0022839)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma