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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxc9a

Z-value: 1.10

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Transcription factors associated with hoxc9a

Gene Symbol Gene ID Gene Info
hoxc9a
ENSDARG00000092809 homeobox C9a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc9adr11_v1_chr23_+_36095260_360952600.075.3e-01Click!

Activity profile of hoxc9a motif

Sorted Z-values of hoxc9a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_47633438 26.97 ENSDART00000139096
si:ch211-251b21.1
si:ch211-251b21.1
chr17_+_23300827 23.70 ENSDART00000058745
zgc:165461
zgc:165461
chr25_-_13842618 17.77 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr8_+_16004154 17.56 ENSDART00000134787
ENSDART00000172510
ENSDART00000141173
elavl4
ELAV like neuron-specific RNA binding protein 4
chr11_-_6188413 16.71 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr8_+_22931427 14.54 ENSDART00000063096
sypa
synaptophysin a
chr13_-_43599898 12.28 ENSDART00000084416
ENSDART00000145705
ablim1a
actin binding LIM protein 1a
chr3_-_61205711 10.95 ENSDART00000055062
pvalb1
parvalbumin 1
chr17_+_19626479 10.82 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr15_+_8043751 10.79 ENSDART00000193701
cadm2b
cell adhesion molecule 2b
chr10_-_19801821 10.78 ENSDART00000148013
gfra2b
GDNF family receptor alpha 2b
chr17_+_45454943 10.69 ENSDART00000074838
kcnk3b
potassium channel, subfamily K, member 3b
chr5_-_51619262 10.64 ENSDART00000134606
ENSDART00000081249
otpb
orthopedia homeobox b
chr15_-_5467477 9.93 ENSDART00000123839
arrb1
arrestin, beta 1
chr3_+_34821327 9.81 ENSDART00000055262
cdk5r1a
cyclin-dependent kinase 5, regulatory subunit 1a (p35)
chr1_-_23157583 9.80 ENSDART00000144208
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr11_-_13341483 9.73 ENSDART00000164978
mast3b
microtubule associated serine/threonine kinase 3b
chr10_+_26571174 9.48 ENSDART00000148617
ENSDART00000112956
slc9a6b
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr2_+_34967022 9.48 ENSDART00000134926
astn1
astrotactin 1
chr14_+_21783400 9.17 ENSDART00000164023
ankrd13d
ankyrin repeat domain 13 family, member D
chr10_+_20128267 9.05 ENSDART00000064615
dmtn
dematin actin binding protein
chr25_-_7999756 8.21 ENSDART00000159908
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr7_-_26408472 7.37 ENSDART00000111494
gal3st4
galactose-3-O-sulfotransferase 4
chr17_+_18117029 7.31 ENSDART00000154646
ENSDART00000179739
bcl11ba
B cell CLL/lymphoma 11Ba
chr9_-_3671911 7.24 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr1_+_16144615 7.13 ENSDART00000054707
tusc3
tumor suppressor candidate 3
chr4_+_10017049 7.10 ENSDART00000144175
ccdc136b
coiled-coil domain containing 136b
chr4_+_11439511 7.07 ENSDART00000150485
pcloa
piccolo presynaptic cytomatrix protein a
chr17_+_32343121 6.83 ENSDART00000156051
dhx32b
DEAH (Asp-Glu-Ala-His) box polypeptide 32b
chr5_-_11573490 6.69 ENSDART00000109577
FO704871.1

chr25_+_3058924 6.61 ENSDART00000029580
fth1b
ferritin, heavy polypeptide 1b
chr15_+_22722684 6.46 ENSDART00000156760
grik4
glutamate receptor, ionotropic, kainate 4
chr18_-_2433011 6.38 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr7_-_41964877 6.32 ENSDART00000092351
ENSDART00000193395
ENSDART00000187947
neto2b
neuropilin (NRP) and tolloid (TLL)-like 2b
chr22_-_21046654 6.27 ENSDART00000064902
ssbp4
single stranded DNA binding protein 4
chr4_-_4261673 6.27 ENSDART00000150694
cd9b
CD9 molecule b
chr1_-_39943596 6.16 ENSDART00000149730
stox2a
storkhead box 2a
chr20_-_36107422 6.13 ENSDART00000146055
ptchd4
patched domain containing 4
chr18_-_26510545 6.07 ENSDART00000135133
FRMD5
si:ch211-69m14.1
chr2_+_2223837 6.00 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr11_-_13341051 5.21 ENSDART00000121872
mast3b
microtubule associated serine/threonine kinase 3b
chr7_+_31051213 5.20 ENSDART00000148347
tjp1a
tight junction protein 1a
chr14_+_11762991 5.16 ENSDART00000110004
frmpd3
FERM and PDZ domain containing 3
chr19_-_36234185 4.93 ENSDART00000186003
csmd2
CUB and Sushi multiple domains 2
chr5_-_51619742 4.83 ENSDART00000188537
otpb
orthopedia homeobox b
chr15_-_14375452 4.76 ENSDART00000160675
ENSDART00000164028
ENSDART00000171642
dpf1
D4, zinc and double PHD fingers family 1
chr7_-_31938938 4.75 ENSDART00000132353
bdnf
brain-derived neurotrophic factor
chr17_-_20849879 4.69 ENSDART00000088100
ENSDART00000149630
ank3b
ankyrin 3b
chr9_+_44722205 4.50 ENSDART00000086176
ENSDART00000145271
ENSDART00000132696
nckap1
NCK-associated protein 1
chr21_+_42930558 4.49 ENSDART00000135234
stk32a
serine/threonine kinase 32A
chr2_-_18830722 4.48 ENSDART00000165330
ENSDART00000165698
pbx1a
pre-B-cell leukemia homeobox 1a
chr3_-_37699992 4.34 ENSDART00000151193
gpatch8
G patch domain containing 8
chr11_+_25044082 4.32 ENSDART00000123263
phf20a
PHD finger protein 20, a
chr7_+_31051603 4.28 ENSDART00000108721
tjp1a
tight junction protein 1a
chr4_-_20235904 4.23 ENSDART00000146621
ENSDART00000193655
stk38l
serine/threonine kinase 38 like
chr7_+_38811800 4.17 ENSDART00000052322
zgc:110699
zgc:110699
chr11_-_3334248 4.08 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr11_+_16040680 3.97 ENSDART00000157703
agtrap
angiotensin II receptor-associated protein
chr15_+_28116129 3.93 ENSDART00000185157
unc119a
unc-119 homolog a (C. elegans)
chr1_-_39909985 3.78 ENSDART00000181673
stox2a
storkhead box 2a
chr18_-_39288894 3.77 ENSDART00000186216
mapk6
mitogen-activated protein kinase 6
chr19_+_41006975 3.43 ENSDART00000138555
ENSDART00000049842
casd1
CAS1 domain containing 1
chr15_+_8767650 3.36 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr2_-_41723165 3.24 ENSDART00000155577
zgc:110158
zgc:110158
chr6_+_38845697 3.23 ENSDART00000053187
stk35l
serine/threonine kinase 35, like
chr13_+_22316746 3.21 ENSDART00000188968
usp54a
ubiquitin specific peptidase 54a
chr14_-_4044545 3.16 ENSDART00000169527
snx25
sorting nexin 25
chr19_+_4916233 3.06 ENSDART00000159512
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr5_-_37871526 3.00 ENSDART00000136450
arhgap35b
Rho GTPase activating protein 35b
chr23_+_20669149 2.98 ENSDART00000138936
arhgef3l
Rho guanine nucleotide exchange factor (GEF) 3, like
chr17_+_26208630 2.95 ENSDART00000087084
grid1a
glutamate receptor, ionotropic, delta 1a
chr23_-_3721444 2.84 ENSDART00000141682
nudt3a
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr9_-_25255490 2.78 ENSDART00000141502
htr2aa
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a
chr2_-_41723487 2.68 ENSDART00000170171
zgc:110158
zgc:110158
chr14_+_36231126 2.64 ENSDART00000141766
elovl6
ELOVL fatty acid elongase 6
chr12_+_27213733 2.50 ENSDART00000133048
nbr1a
neighbor of brca1 gene 1a
chr14_-_30141162 2.47 ENSDART00000053916
mtnr1ab
melatonin receptor 1A b
chr21_+_22878991 2.43 ENSDART00000186399
pcf11
PCF11 cleavage and polyadenylation factor subunit
chr6_+_55032439 2.42 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
mybphb
myosin binding protein Hb
chr21_+_22878834 2.06 ENSDART00000065562
pcf11
PCF11 cleavage and polyadenylation factor subunit
chr20_+_27464721 2.05 ENSDART00000189552
kif26aa
kinesin family member 26Aa
chr4_+_21867522 2.02 ENSDART00000140400
acss3
acyl-CoA synthetase short chain family member 3
chr22_+_10713713 1.89 ENSDART00000122349
hiat1b
hippocampus abundant transcript 1b
chr25_-_5963535 1.86 ENSDART00000155751
nuak1b
NUAK family, SNF1-like kinase, 1b
chr9_-_34937025 1.76 ENSDART00000137888
cdc16
cell division cycle 16 homolog (S. cerevisiae)
chr6_+_52804267 1.75 ENSDART00000065681
matn4
matrilin 4
chr15_-_14589677 1.67 ENSDART00000172195
coq8b
coenzyme Q8B
chr5_+_63857055 1.64 ENSDART00000138950
rgs3b
regulator of G protein signaling 3b
chr2_-_9259283 1.62 ENSDART00000133092
st6galnac5a
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5a
chr7_-_41693004 1.55 ENSDART00000121509
malrd1
MAM and LDL receptor class A domain containing 1
chr20_+_23658791 1.51 ENSDART00000192145
si:ch211-191d2.2
si:ch211-191d2.2
chr17_-_51262430 1.49 ENSDART00000163222
trappc12
trafficking protein particle complex 12
chr22_-_21046843 1.41 ENSDART00000133982
ssbp4
single stranded DNA binding protein 4
chr20_-_53949798 1.32 ENSDART00000153435
ppp2r5cb
protein phosphatase 2, regulatory subunit B', gamma b
chr19_-_27830818 1.30 ENSDART00000131767
papd7
PAP associated domain containing 7
chr3_-_40232615 1.24 ENSDART00000155969
flii
flightless I actin binding protein
chr3_-_12930217 1.22 ENSDART00000166322
pdgfab
platelet-derived growth factor alpha polypeptide b
chr14_-_17072736 1.07 ENSDART00000106333
phox2bb
paired-like homeobox 2bb
chr12_-_20362041 1.03 ENSDART00000184145
ENSDART00000105952
aqp8a.2
aquaporin 8a, tandem duplicate 2
chr12_-_16380961 0.89 ENSDART00000086984
hectd2
HECT domain containing 2
chr12_-_16380593 0.86 ENSDART00000152133
hectd2
HECT domain containing 2
chr11_+_18873113 0.76 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr16_+_37891735 0.74 ENSDART00000178753
ENSDART00000142104
cep162
centrosomal protein 162
chr17_-_30839338 0.74 ENSDART00000139707
gdf7
growth differentiation factor 7
chr17_-_25630822 0.68 ENSDART00000126201
ENSDART00000105503
ENSDART00000151878
rab3gap2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr21_-_131236 0.67 ENSDART00000160005
si:ch1073-398f15.1
si:ch1073-398f15.1
chr9_+_16449398 0.54 ENSDART00000006787
epha3
eph receptor A3
chr3_-_23461954 0.54 ENSDART00000040065
casc3
cancer susceptibility candidate 3
chr3_+_25825043 0.38 ENSDART00000153749
pik3r6b
phosphoinositide-3-kinase, regulatory subunit 6b
chr6_-_46875310 0.35 ENSDART00000154442
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr4_-_18635005 0.30 ENSDART00000125361
pparaa
peroxisome proliferator-activated receptor alpha a
chr22_+_35089031 0.23 ENSDART00000076040
srfa
serum response factor a
chr3_-_23470986 0.21 ENSDART00000113135
msl1a
male-specific lethal 1 homolog a (Drosophila)
chr13_+_15004398 0.20 ENSDART00000057810
emx1
empty spiracles homeobox 1
chr12_+_18744610 0.07 ENSDART00000153456
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr3_-_8388344 0.07 ENSDART00000146856
rbfox3b
RNA binding fox-1 homolog 3b
chr23_+_3721042 0.06 ENSDART00000143323
smim29
small integral membrane protein 29
chr10_+_13000669 0.04 ENSDART00000158919
ENSDART00000172625
lpar1
lysophosphatidic acid receptor 1
chr12_-_16380242 0.03 ENSDART00000168105
hectd2
HECT domain containing 2
chr4_-_20118468 0.03 ENSDART00000078587
si:dkey-159a18.1
si:dkey-159a18.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc9a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 15.5 GO:0021767 mammillary body development(GO:0021767)
2.5 9.9 GO:1900120 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.9 6.6 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.9 6.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.9 21.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.9 9.5 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.9 9.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.7 4.5 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.7 7.1 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.6 4.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.6 2.8 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.5 7.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.5 9.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.5 3.9 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.4 10.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.4 7.1 GO:0015693 magnesium ion transport(GO:0015693)
0.4 3.4 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.4 4.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 16.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.4 6.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.4 9.8 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.3 36.4 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.3 17.8 GO:0046328 regulation of JNK cascade(GO:0046328)
0.3 1.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.2 9.8 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.2 0.5 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 9.0 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.1 1.8 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 1.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 27.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 2.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 3.2 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 1.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 7.3 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.1 1.7 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 6.3 GO:0007338 single fertilization(GO:0007338)
0.1 2.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 3.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 10.8 GO:0021782 glial cell development(GO:0021782)
0.1 4.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 23.7 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 4.5 GO:0016573 histone acetylation(GO:0016573)
0.0 17.2 GO:0008380 RNA splicing(GO:0008380)
0.0 1.2 GO:0051014 actin filament severing(GO:0051014)
0.0 4.1 GO:0042246 tissue regeneration(GO:0042246)
0.0 10.6 GO:0009968 negative regulation of signal transduction(GO:0009968) negative regulation of signaling(GO:0023057)
0.0 0.2 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 3.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 17.0 GO:0007267 cell-cell signaling(GO:0007267)
0.0 2.5 GO:0016236 macroautophagy(GO:0016236)
0.0 3.1 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 1.3 GO:0071375 regulation of blood pressure(GO:0008217) cellular response to peptide hormone stimulus(GO:0071375) cellular response to peptide(GO:1901653)
0.0 0.7 GO:0060393 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 33.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
2.0 9.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.7 4.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.7 7.1 GO:0098982 GABA-ergic synapse(GO:0098982)
0.5 7.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 17.6 GO:0043204 perikaryon(GO:0043204)
0.4 3.9 GO:0045171 intercellular bridge(GO:0045171)
0.3 3.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 4.3 GO:0044545 NSL complex(GO:0044545)
0.2 12.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 4.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 4.8 GO:0071565 nBAF complex(GO:0071565)
0.2 14.2 GO:0048786 presynaptic active zone(GO:0048786)
0.2 1.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.7 GO:0005879 axonemal microtubule(GO:0005879)
0.1 9.5 GO:0055037 recycling endosome(GO:0055037)
0.1 1.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 2.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 2.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 1.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 9.2 GO:0005770 late endosome(GO:0005770)
0.1 6.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 12.5 GO:0030424 axon(GO:0030424)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 10.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 5.9 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.4 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 2.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 9.9 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 17.0 GO:0005615 extracellular space(GO:0005615)
0.0 3.0 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 33.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
3.6 10.7 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.9 9.5 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.8 7.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.8 9.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.6 2.8 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.6 6.6 GO:0008199 ferric iron binding(GO:0008199)
0.4 2.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.4 2.0 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.4 7.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.4 16.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.4 4.8 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.4 14.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 3.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.2 23.7 GO:0019838 growth factor binding(GO:0019838)
0.2 1.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 4.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 8.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 3.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 13.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 2.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.0 GO:0015250 water channel activity(GO:0015250)
0.1 3.8 GO:0004707 MAP kinase activity(GO:0004707)
0.1 3.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 3.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 9.4 GO:0000287 magnesium ion binding(GO:0000287)
0.1 2.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 6.8 GO:0004386 helicase activity(GO:0004386)
0.0 13.4 GO:0051015 actin filament binding(GO:0051015)
0.0 9.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 2.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 5.0 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 3.2 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 4.6 GO:0042393 histone binding(GO:0042393)
0.0 1.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 5.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 4.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 4.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 9.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3 3.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.3 2.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 4.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.2 3.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 7.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation