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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxd10a

Z-value: 0.46

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Transcription factors associated with hoxd10a

Gene Symbol Gene ID Gene Info
hoxd10a
ENSDARG00000057859 homeobox D10a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd10adr11_v1_chr9_-_1970071_1970071-0.363.9e-04Click!

Activity profile of hoxd10a motif

Sorted Z-values of hoxd10a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_45178430 3.55 ENSDART00000165186
si:dkey-33i11.9
si:dkey-33i11.9
chr14_+_38786298 2.99 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr8_+_36142734 2.81 ENSDART00000159361
ENSDART00000161194
mhc2b
major histocompatibility complex class II integral membrane beta chain gene
chr22_-_38819603 2.65 ENSDART00000104437
si:ch211-262h13.5
si:ch211-262h13.5
chr17_+_42274825 2.03 ENSDART00000020156
pax1a
paired box 1a
chr4_-_16824556 1.98 ENSDART00000165289
ENSDART00000185839
gys2
glycogen synthase 2
chr5_+_22459087 1.82 ENSDART00000134781
BX546499.1

chr13_-_31017960 1.81 ENSDART00000145287
wdfy4
WDFY family member 4
chr5_-_23805387 1.76 ENSDART00000133805
gbgt1l4
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr2_-_1486023 1.65 ENSDART00000113774
si:ch211-188c16.1
si:ch211-188c16.1
chr18_+_15644559 1.62 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr5_+_35458346 1.59 ENSDART00000141239
erlin2
ER lipid raft associated 2
chr2_+_10280645 1.47 ENSDART00000063996
gadd45aa
growth arrest and DNA-damage-inducible, alpha, a
chr14_+_26439227 1.46 ENSDART00000054183
gpr137
G protein-coupled receptor 137
chr11_+_37265692 1.45 ENSDART00000184691
il17rc
interleukin 17 receptor C
chr13_-_50108337 1.45 ENSDART00000133308
nid1a
nidogen 1a
chr16_-_42186093 1.38 ENSDART00000076030
fbl
fibrillarin
chr2_-_42628028 1.36 ENSDART00000179866
myo10
myosin X
chr5_+_50912729 1.27 ENSDART00000190837
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr18_+_31056645 1.21 ENSDART00000159316
mvda
mevalonate (diphospho) decarboxylase a
chr21_+_15295685 1.18 ENSDART00000135603
BX901878.1

chr21_-_3796461 1.16 ENSDART00000021976
nsa2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr6_+_29386728 1.15 ENSDART00000104303
actl6a
actin-like 6A
chr25_-_3217115 1.15 ENSDART00000032390
gtf2h1
general transcription factor IIH, polypeptide 1
chr18_+_7363242 1.10 ENSDART00000133375
si:dkey-30c15.17
si:dkey-30c15.17
chr20_+_13894123 1.04 ENSDART00000007744
slc30a1a
solute carrier family 30 (zinc transporter), member 1a
chr20_+_18993452 1.03 ENSDART00000025509
tdh
L-threonine dehydrogenase
chr1_-_52431220 1.03 ENSDART00000111256
zgc:194101
zgc:194101
chr6_-_15757867 1.02 ENSDART00000063665
ackr3b
atypical chemokine receptor 3b
chr18_+_7543347 1.01 ENSDART00000103467
arf5
ADP-ribosylation factor 5
chr13_+_27232848 0.99 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr18_-_20458412 0.98 ENSDART00000012241
kif23
kinesin family member 23
chr20_-_30931139 0.98 ENSDART00000006778
ENSDART00000146376
acat2
acetyl-CoA acetyltransferase 2
chr6_-_39521832 0.96 ENSDART00000065038
atf1
activating transcription factor 1
chr16_+_12281032 0.94 ENSDART00000138638
si:dkey-26c10.5
si:dkey-26c10.5
chr16_-_43233509 0.89 ENSDART00000025877
cldn12
claudin 12
chr19_-_3056235 0.89 ENSDART00000137020
bop1
block of proliferation 1
chr10_-_3138403 0.88 ENSDART00000183365
ube2l3a
ubiquitin-conjugating enzyme E2L 3a
chr7_-_22981796 0.85 ENSDART00000167565
si:dkey-171c9.3
si:dkey-171c9.3
chr11_-_39118882 0.83 ENSDART00000113185
ENSDART00000156526
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr23_+_28322986 0.83 ENSDART00000134710
birc5b
baculoviral IAP repeat containing 5b
chr3_-_40768548 0.83 ENSDART00000004923
smurf1
SMAD specific E3 ubiquitin protein ligase 1
chr21_+_21279159 0.83 ENSDART00000148346
itpkca
inositol-trisphosphate 3-kinase Ca
chr3_-_26184018 0.83 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr9_+_21151138 0.80 ENSDART00000133903
hao2
hydroxyacid oxidase 2 (long chain)
chr10_+_44692272 0.80 ENSDART00000157458
ubc
ubiquitin C
chr10_-_22491353 0.79 ENSDART00000180783
ENSDART00000159564
epob
erythropoietin b
chr19_+_47299212 0.78 ENSDART00000158262
tpmt.1
thiopurine S-methyltransferase, tandem duplicate 1
chr4_-_76270779 0.75 ENSDART00000183709
ENSDART00000192689
si:ch211-106j21.4
si:ch211-106j21.4
chr21_+_3796620 0.70 ENSDART00000099535
ENSDART00000144515
spout1
SPOUT domain containing methyltransferase 1
chr11_-_31039533 0.70 ENSDART00000127355
ier2b
immediate early response 2b
chr11_-_42752884 0.69 ENSDART00000186025
si:ch73-106k19.5
si:ch73-106k19.5
chr18_-_2222128 0.67 ENSDART00000171402
pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr7_+_22982201 0.66 ENSDART00000134116
ccnb3
cyclin B3
chr21_-_41025340 0.66 ENSDART00000148231
plac8l1
PLAC8-like 1
chr1_-_37377509 0.65 ENSDART00000113542
tnip2
TNFAIP3 interacting protein 2
chr11_+_14104417 0.64 ENSDART00000059752
ENSDART00000186575
med16
mediator complex subunit 16
chr4_-_67589158 0.63 ENSDART00000184361
BX088712.2

chr1_-_669717 0.63 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr14_-_32959851 0.62 ENSDART00000075157
chic1
cysteine-rich hydrophobic domain 1
chr3_-_29899172 0.60 ENSDART00000140518
ENSDART00000020311
rpl27
ribosomal protein L27
chr6_-_25165693 0.60 ENSDART00000167259
znf326
zinc finger protein 326
chr3_-_11828206 0.59 ENSDART00000018159
si:ch211-262e15.1
si:ch211-262e15.1
chr9_-_19489264 0.59 ENSDART00000122894
wdr4
WD repeat domain 4
chr8_-_15292197 0.59 ENSDART00000140867
spata6
spermatogenesis associated 6
chr6_+_12316438 0.59 ENSDART00000156854
si:dkey-276j7.2
si:dkey-276j7.2
chr19_-_35450661 0.57 ENSDART00000113574
ENSDART00000136895
anln
anillin, actin binding protein
chr7_-_24373662 0.56 ENSDART00000173865
PTGR1 (1 of many)
si:dkey-11k2.7
chr21_+_3796196 0.55 ENSDART00000146754
spout1
SPOUT domain containing methyltransferase 1
chr21_+_5192016 0.54 ENSDART00000139288
si:dkey-121h17.7
si:dkey-121h17.7
chr19_-_10324573 0.54 ENSDART00000171795
u2af2b
U2 small nuclear RNA auxiliary factor 2b
chr5_+_25317061 0.54 ENSDART00000170097
trpm6
transient receptor potential cation channel, subfamily M, member 6
chr25_-_12412704 0.53 ENSDART00000168275
det1
DET1, COP1 ubiquitin ligase partner
chr19_+_13994563 0.52 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr12_+_30788912 0.51 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr11_-_27953135 0.50 ENSDART00000168338
ece1
endothelin converting enzyme 1
chr19_+_4051535 0.49 ENSDART00000167084
btr24
bloodthirsty-related gene family, member 24
chr10_-_26985231 0.49 ENSDART00000050585
znhit2
zinc finger, HIT-type containing 2
chr6_+_9793791 0.47 ENSDART00000149896
als2b
amyotrophic lateral sclerosis 2b (juvenile)
chr16_-_26296477 0.47 ENSDART00000157553
erfl1
Ets2 repressor factor like 1
chr9_-_3519717 0.46 ENSDART00000145043
dcaf17
ddb1 and cul4 associated factor 17
chr13_+_27232694 0.44 ENSDART00000131128
rin2
Ras and Rab interactor 2
chr10_+_22527715 0.43 ENSDART00000134864
gigyf1b
GRB10 interacting GYF protein 1b
chr1_-_18811517 0.41 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr1_-_19764038 0.38 ENSDART00000005733
tma16
translation machinery associated 16 homolog
chr24_+_17069420 0.37 ENSDART00000014787
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr6_+_1787160 0.34 ENSDART00000113505
myl9b
myosin, light chain 9b, regulatory
chr7_+_4194306 0.33 ENSDART00000190454
si:dkey-28d5.5
si:dkey-28d5.5
chr5_+_6672870 0.32 ENSDART00000126598
pxna
paxillin a
chr9_+_45605410 0.32 ENSDART00000136444
ENSDART00000007189
ENSDART00000158713
ENSDART00000182671
traf3ip1
TNF receptor-associated factor 3 interacting protein 1
chr22_+_22302614 0.32 ENSDART00000049434
scamp4
secretory carrier membrane protein 4
chr9_+_3519191 0.31 ENSDART00000008606
mettl8
methyltransferase like 8
chr13_-_24669258 0.30 ENSDART00000000831
znf511
zinc finger protein 511
chr10_-_17484762 0.30 ENSDART00000137905
ENSDART00000007961
nt5c2l1
5'-nucleotidase, cytosolic II, like 1
chr16_+_41060161 0.29 ENSDART00000141130
scap
SREBF chaperone
chr14_+_20941038 0.29 ENSDART00000182539
zgc:66433
zgc:66433
chr17_-_28707898 0.29 ENSDART00000135752
ENSDART00000061853
ap4s1
adaptor-related protein complex 4, sigma 1 subunit
chr4_+_64339299 0.28 ENSDART00000191590
si:ch211-223a21.1
si:ch211-223a21.1
chr10_-_20453995 0.28 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
si:ch211-113d22.2
chr3_-_26191960 0.27 ENSDART00000113843
ypel3
yippee-like 3
chr10_+_41986685 0.27 ENSDART00000086165
ENSDART00000171983
setd1ba
SET domain containing 1B, a
chr24_+_15655233 0.27 ENSDART00000143160
fbxo15
F-box protein 15
chr1_+_32341734 0.23 ENSDART00000135078
pudp
pseudouridine 5'-phosphatase
chr3_-_17871846 0.23 ENSDART00000074478
ENSDART00000187941
nkiras2
NFKB inhibitor interacting Ras-like 2
chr17_+_31621788 0.22 ENSDART00000111629
ENSDART00000157148
cinp
cyclin-dependent kinase 2 interacting protein
chr2_+_21356242 0.22 ENSDART00000145670
ENSDART00000146600
ctdsplb
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr3_-_25107802 0.22 ENSDART00000055432
rbx1
ring-box 1, E3 ubiquitin protein ligase
chr16_+_54829293 0.19 ENSDART00000024729
pabpc1a
poly(A) binding protein, cytoplasmic 1a
chr1_+_26105141 0.18 ENSDART00000102379
ENSDART00000127154
toporsa
topoisomerase I binding, arginine/serine-rich a
chr11_-_7156620 0.18 ENSDART00000172823
ENSDART00000172879
ENSDART00000078916
smim7
small integral membrane protein 7
chr6_-_41079209 0.17 ENSDART00000151592
rab44
RAB44, member RAS oncogene family
chr25_+_34915576 0.16 ENSDART00000073441
sntb2
syntrophin, beta 2
chr7_+_22981909 0.16 ENSDART00000122449
ccnb3
cyclin B3
chr24_+_15655069 0.16 ENSDART00000042943
ENSDART00000181296
fbxo15
F-box protein 15
chr3_-_43954343 0.16 ENSDART00000157580
ubfd1
ubiquitin family domain containing 1
chr6_+_13201358 0.14 ENSDART00000190290
CT009620.1

chr6_+_39290777 0.14 ENSDART00000155700
si:dkey-195m11.11
si:dkey-195m11.11
chr17_-_12764360 0.13 ENSDART00000003418
brms1la
breast cancer metastasis-suppressor 1-like a
chr7_+_4694924 0.11 ENSDART00000144873
si:ch211-225k7.3
si:ch211-225k7.3
chr15_+_1134870 0.10 ENSDART00000155392
p2ry13
purinergic receptor P2Y13
chr10_-_2788668 0.08 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr14_+_44804326 0.07 ENSDART00000079866
ENSDART00000172974
slc30a9
solute carrier family 30 (zinc transporter), member 9
chr20_-_25445237 0.06 ENSDART00000145034
ENSDART00000018049
mrpl19
mitochondrial ribosomal protein L19
chr1_-_17711636 0.05 ENSDART00000148322
ENSDART00000122670
ufsp2
ufm1-specific peptidase 2
chr6_-_14040136 0.05 ENSDART00000065361
ENSDART00000179765
etv5b
ets variant 5b
chr4_-_17680493 0.03 ENSDART00000180131
BX890572.2

chr13_-_18069421 0.02 ENSDART00000146772
ENSDART00000134477
zfand4
zinc finger, AN1-type domain 4
chr9_-_3519253 0.02 ENSDART00000169586
dcaf17
ddb1 and cul4 associated factor 17
chr7_+_4938463 0.02 ENSDART00000143722
si:dkey-28d5.14
si:dkey-28d5.14
chr22_-_36750589 0.01 ENSDART00000010824
acy1
aminoacylase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd10a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.3 1.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 1.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3 0.8 GO:0000212 meiotic spindle organization(GO:0000212)
0.3 1.0 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.2 0.6 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138)
0.2 1.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 1.4 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.1 0.6 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 1.9 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.6 GO:0008356 asymmetric cell division(GO:0008356)
0.1 1.0 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.8 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.0 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 1.5 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.8 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.1 1.8 GO:0030259 lipid glycosylation(GO:0030259)
0.1 1.6 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 2.0 GO:0009749 response to glucose(GO:0009749)
0.1 2.8 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 1.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 2.0 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 5.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.8 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0090660 regulation of microtubule polymerization(GO:0031113) cerebrospinal fluid circulation(GO:0090660)
0.0 1.2 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.4 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.8 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.3 GO:0061055 myotome development(GO:0061055)
0.0 0.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.5 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.5 GO:0051262 protein tetramerization(GO:0051262)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 0.9 GO:0070545 PeBoW complex(GO:0070545)
0.2 1.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.6 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.2 1.2 GO:0000439 core TFIIH complex(GO:0000439)
0.2 1.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 0.6 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.6 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.6 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.2 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 2.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 1.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.3 1.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.3 1.6 GO:0032052 bile acid binding(GO:0032052)
0.3 0.8 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.3 0.8 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.2 1.0 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.2 0.6 GO:0032027 myosin light chain binding(GO:0032027)
0.2 1.1 GO:0004104 cholinesterase activity(GO:0004104)
0.1 0.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 1.2 GO:0035198 miRNA binding(GO:0035198)
0.1 1.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.5 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.4 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 3.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.0 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.8 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.8 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.0 GO:0016248 calcium channel regulator activity(GO:0005246) ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 2.5 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.8 GO:0010181 FMN binding(GO:0010181)
0.0 0.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 3.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.2 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 2.0 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling