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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxd4a

Z-value: 0.43

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Transcription factors associated with hoxd4a

Gene Symbol Gene ID Gene Info
ENSDARG00000059276 homeobox D4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd4adr11_v1_chr9_-_1951144_1951144-0.028.7e-01Click!

Activity profile of hoxd4a motif

Sorted Z-values of hoxd4a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_2495197 3.33 ENSDART00000146887
coagulation factor XIII, A1 polypeptide a, tandem duplicate 1
chr24_+_38301080 2.97 ENSDART00000105672
myosin binding protein C, fast type b
chr1_-_18811517 2.43 ENSDART00000142026
si:dkey-167i21.2
chr17_-_2578026 2.26 ENSDART00000065821
zona pellucida glycoprotein 3, tandem duplicate 2
chr25_+_31277415 2.25 ENSDART00000036275
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr7_-_38698583 1.92 ENSDART00000173900
ENSDART00000126737
CD59 molecule (CD59 blood group)
chr25_+_31276842 1.84 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr19_-_3167729 1.74 ENSDART00000110763
ENSDART00000145710
ENSDART00000074620
ENSDART00000105174
starmaker
chr24_-_9985019 1.70 ENSDART00000193536
ENSDART00000189595
zgc:171977
chr7_-_20582842 1.54 ENSDART00000169750
ENSDART00000111719
si:dkey-19b23.11
chr11_+_18183220 1.54 ENSDART00000113468

chr24_-_9979342 1.52 ENSDART00000138576
ENSDART00000191206
zgc:171977
chr3_+_24361096 1.39 ENSDART00000132387
parvalbumin 6
chr4_+_7841627 1.39 ENSDART00000037997
upper zone of growth plate and cartilage matrix associated a
chr7_-_24699985 1.17 ENSDART00000052802
calbindin 2b
chr4_-_14915268 1.09 ENSDART00000067040
si:dkey-180p18.9
chr6_-_46861676 1.07 ENSDART00000188712
ENSDART00000190148
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr4_-_4387012 1.06 ENSDART00000191836
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr10_-_7756865 1.05 ENSDART00000114373
ENSDART00000125407
ENSDART00000016317
lysyl oxidase a
chr13_-_9318891 1.04 ENSDART00000137364
si:dkey-33c12.3
chr20_-_29474859 0.93 ENSDART00000152906
ENSDART00000045249
secretogranin V
chr22_+_25774750 0.92 ENSDART00000174421

chr10_-_26202766 0.89 ENSDART00000136393
FH2 domain containing 3
chr23_+_19590006 0.86 ENSDART00000021231
sarcolemma associated protein b
chr4_+_14981854 0.81 ENSDART00000067046
cation/H+ exchanger protein 1
chr2_+_56657804 0.78 ENSDART00000113964
RNA polymerase II subunit E
chr18_+_29156827 0.75 ENSDART00000137587
ENSDART00000135633
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr22_-_10470663 0.74 ENSDART00000143352
osteomodulin
chr14_-_33894915 0.71 ENSDART00000143290
urotensin-related peptide 1
chr17_+_23298928 0.70 ENSDART00000153652
zgc:165461
chr19_-_47527093 0.70 ENSDART00000171379
ENSDART00000171140
ENSDART00000114886
secretogranin V
chr2_+_20605186 0.65 ENSDART00000128505
olfactomedin-like 2Bb
chr7_+_44802353 0.63 ENSDART00000066380
carbonic anhydrase VII
chr14_-_35462148 0.62 ENSDART00000045809
sushi-repeat containing protein, X-linked 2
chr3_+_26123736 0.62 ENSDART00000010477
heat shock cognate 70-kd protein, tandem duplicate 3
chr19_+_24872159 0.61 ENSDART00000158490
si:ch211-195b13.1
chr13_-_7567707 0.60 ENSDART00000190296
ENSDART00000180348
paired-like homeodomain 3
chr23_-_21453614 0.58 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr17_-_4252221 0.57 ENSDART00000152020
growth differentiation factor 3
chr6_+_21001264 0.55 ENSDART00000044519
ENSDART00000151278
connexin 44.2
chr3_-_32337653 0.55 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr16_-_55028740 0.51 ENSDART00000156368
ENSDART00000161704
zgc:114181
chr8_+_3820134 0.51 ENSDART00000122454
citron rho-interacting serine/threonine kinase b
chr24_+_15020402 0.51 ENSDART00000148102
docking protein 6
chr16_+_13818500 0.50 ENSDART00000135245
folliculin
chr23_-_31913069 0.50 ENSDART00000135526
mitochondrial fission regulator 2
chr11_+_25259058 0.50 ENSDART00000154109
tumor protein p53 inducible nuclear protein 2
chr9_+_29548195 0.49 ENSDART00000176057
ring finger protein 17
chr15_+_23657051 0.48 ENSDART00000078336
kinesin light chain 3
chr6_+_36839509 0.47 ENSDART00000190605
ENSDART00000104160
zgc:110788
chr22_+_38037530 0.47 ENSDART00000012212
COMM domain containing 2
chr14_+_26247319 0.46 ENSDART00000192793
coiled-coil domain containing 69
chr25_+_3318192 0.45 ENSDART00000146154
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr23_-_31913231 0.45 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr3_-_49382896 0.45 ENSDART00000169115
si:ch73-167f10.1
chr12_-_34435604 0.44 ENSDART00000115088
baculoviral IAP repeat containing 5a
chr7_+_20017211 0.44 ENSDART00000100808
B-cell CLL/lymphoma 6, member B
chr15_-_30816370 0.44 ENSDART00000142982
ENSDART00000050649
ENSDART00000136901
ENSDART00000100194
musashi RNA-binding protein 2b
chr20_+_23173710 0.41 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr8_+_17069577 0.40 ENSDART00000131847
si:dkey-190g11.3
chr14_-_30905288 0.40 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
chr22_+_8753092 0.40 ENSDART00000140720
si:dkey-182g1.2
chr23_-_26652273 0.39 ENSDART00000112124
ENSDART00000111029
heparan sulfate proteoglycan 2
chr4_-_14315855 0.39 ENSDART00000133325
neural EGFL like 2b
chr3_-_31258459 0.39 ENSDART00000177928

chr22_+_8753365 0.39 ENSDART00000106086
si:dkey-182g1.2
chr8_-_34065573 0.39 ENSDART00000186946
pre-B-cell leukemia homeobox 3b
chr6_-_44402358 0.39 ENSDART00000193007
ENSDART00000193603
PDZ domain containing RING finger 3b
chr10_+_21522545 0.38 ENSDART00000131097

chr2_-_45135591 0.38 ENSDART00000014691
ENSDART00000123916
eukaryotic translation initiation factor 4E family member 2
chr3_+_27770110 0.37 ENSDART00000017962
enoyl-CoA delta isomerase 1
chr10_+_39952995 0.37 ENSDART00000183077

chr25_-_10503043 0.37 ENSDART00000155404
cytochrome c oxidase subunit 8b
chr25_-_13839743 0.37 ENSDART00000158780
mitogen-activated protein kinase 8 interacting protein 1a
chr5_-_30491172 0.36 ENSDART00000138464
pleckstrin homology-like domain, family B, member 1a
chr9_+_31534601 0.35 ENSDART00000133094
si:ch211-168k14.2
chr2_+_45362016 0.34 ENSDART00000139154
calmodulin regulated spectrin-associated protein family, member 2b
chr8_+_28467893 0.34 ENSDART00000189724
solute carrier family 52 (riboflavin transporter), member 3
chr9_-_22918413 0.34 ENSDART00000007392
ADP-ribosylation factor-like 5A
chr16_-_41465542 0.33 ENSDART00000169116
ENSDART00000187446
copine IVa
chr2_+_4146299 0.32 ENSDART00000173418
mindbomb E3 ubiquitin protein ligase 1
chr20_+_18551657 0.32 ENSDART00000147001
si:dkeyp-72h1.1
chr25_+_34888886 0.32 ENSDART00000035245
spire-type actin nucleation factor 2
chr4_+_15944245 0.32 ENSDART00000134594
si:dkey-117n7.3
chr16_+_29509133 0.31 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr14_+_15620640 0.31 ENSDART00000188867
si:dkey-203a12.9
chr24_-_21819010 0.31 ENSDART00000091096

chr23_+_404975 0.30 ENSDART00000181336

chr16_-_15988320 0.30 ENSDART00000160883

chr2_+_16696052 0.30 ENSDART00000022356
ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr2_+_33326522 0.30 ENSDART00000056655
Kruppel-like factor 17
chr22_+_28818291 0.30 ENSDART00000136032
tumor protein p53 binding protein, 2b
chr5_+_36611128 0.30 ENSDART00000097684
neuro-oncological ventral antigen 1
chr7_-_5896339 0.30 ENSDART00000172908
si:dkey-23a13.2
chr8_+_52284075 0.29 ENSDART00000098439
ubiquitin-conjugating enzyme E2D 4 (putative)
chr4_-_18202291 0.28 ENSDART00000169704
ankyrin repeat and sterile alpha motif domain containing 1B
chr18_-_16392229 0.28 ENSDART00000189031
mgat4 family, member C
chr18_-_48296793 0.28 ENSDART00000032184
ENSDART00000193076

chr21_+_9689103 0.28 ENSDART00000165132
mitogen-activated protein kinase 10
chr23_-_24343363 0.27 ENSDART00000166392
family with sequence similarity 131, member C
chr23_-_36823932 0.27 ENSDART00000142305
homeodomain interacting protein kinase 1a
chr22_+_37631234 0.27 ENSDART00000007346
proteasome 26S subunit, non-ATPase 1
chr20_+_30939178 0.27 ENSDART00000062556
superoxide dismutase 2, mitochondrial
chr15_-_34658057 0.26 ENSDART00000110964
BCL2 associated athanogene 6
chr8_-_50888806 0.26 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr15_-_45110011 0.25 ENSDART00000182047
ENSDART00000188662

chr7_-_73851280 0.25 ENSDART00000190053

chr2_+_37815687 0.25 ENSDART00000166352
short chain dehydrogenase/reductase family 39U, member 1
chr16_-_17541890 0.24 ENSDART00000131328
chloride channel, voltage-sensitive 1b
chr22_-_2922053 0.24 ENSDART00000178290
p21 protein (Cdc42/Rac)-activated kinase 2b
chr18_+_33310811 0.23 ENSDART00000131587
vomeronasal 2 receptor, a16
chr11_-_30611814 0.23 ENSDART00000089803
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr18_+_34225520 0.22 ENSDART00000126115
vomeronasal 2 receptor, l1
chr11_-_27874116 0.22 ENSDART00000180579
eukaryotic translation initiation factor 4 gamma, 3a
chr6_-_15641686 0.22 ENSDART00000135583
melanophilin a
chr16_+_23403602 0.22 ENSDART00000159848
S100 calcium binding protein W
chr11_-_40101246 0.22 ENSDART00000161083
tumor necrosis factor receptor superfamily, member 9b
chr21_+_37445871 0.22 ENSDART00000076333
phosphoglycerate kinase 1
chr11_-_22303678 0.22 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr16_+_14707960 0.22 ENSDART00000137912
collagen, type XIV, alpha 1a
chr9_+_34380299 0.21 ENSDART00000131705
lysosomal-associated membrane protein 1
chr24_+_26134209 0.21 ENSDART00000038824
teleost multiple tissue opsin b
chr6_+_45692026 0.21 ENSDART00000164759
contactin 4
chr1_+_18811679 0.21 ENSDART00000078610
solute carrier family 25, member 51a
chr4_+_65127317 0.21 ENSDART00000166475
zinc finger protein 1126
chr22_-_12337781 0.21 ENSDART00000188357
ENSDART00000123574
zinc finger, RAN-binding domain containing 3
chr19_-_47455944 0.21 ENSDART00000190005
transcription factor AP-2 epsilon
chr13_+_1726953 0.21 ENSDART00000103004
zmp:0000000760
chr7_-_26532089 0.21 ENSDART00000121698
SUMO1/sentrin/SMT3 specific peptidase 3b
chr5_+_66433287 0.21 ENSDART00000170757
kinetochore associated 1
chr25_-_2723682 0.20 ENSDART00000113382
ADP-dependent glucokinase
chr18_+_16192083 0.20 ENSDART00000133042
leucine-rich repeats and IQ motif containing 1
chr13_+_11440389 0.20 ENSDART00000186463
zinc finger and BTB domain containing 18
chr11_-_28911172 0.19 ENSDART00000168493
immunoglobin superfamily, member 21a
chr22_-_19552796 0.19 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
chr5_+_24520437 0.19 ENSDART00000144560
DGCR8 microprocessor complex subunit
chr5_-_68795063 0.19 ENSDART00000016307
hairy-related 1
chr1_+_50921266 0.19 ENSDART00000006538
orthodenticle homeobox 2a
chr1_-_44157273 0.19 ENSDART00000166618
solute carrier family 43, member 3a
chr24_+_37902687 0.18 ENSDART00000042273
coiled-coil domain containing 78
chr8_-_44004135 0.18 ENSDART00000136269
RIMS binding protein 2
chr24_-_1021318 0.18 ENSDART00000181403
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr2_-_23677422 0.18 ENSDART00000079131
chromodomain protein, Y-like
chr12_+_47907277 0.18 ENSDART00000097714
thymus, brain and testes associated
chr7_-_20758825 0.18 ENSDART00000156717
ENSDART00000182629
ENSDART00000179801
chromodomain helicase DNA binding protein 3
chr1_+_23784905 0.17 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit homolog 2 (Drosophila)
chr1_-_45213565 0.17 ENSDART00000145757
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr24_-_13364311 0.17 ENSDART00000183808
si:dkey-192j17.1
chr14_-_32089117 0.17 ENSDART00000158014
si:ch211-69b22.5
chr17_+_32343121 0.17 ENSDART00000156051
DEAH (Asp-Glu-Ala-His) box polypeptide 32b
chr18_-_5392667 0.17 ENSDART00000169896

chr24_-_35707552 0.16 ENSDART00000165199
microtubule-associated protein, RP/EB family, member 2
chr14_-_31618243 0.16 ENSDART00000016592
membrane magnesium transporter 1
chr3_+_32691275 0.16 ENSDART00000191838
si:dkey-16l2.17
chr24_-_3426620 0.16 ENSDART00000184346
NCK adaptor protein 1b
chr5_-_31856681 0.15 ENSDART00000187817
protein kinase N3
chr25_+_30074947 0.15 ENSDART00000154849
si:ch211-147k10.5
chr8_+_8238727 0.15 ENSDART00000144838
plexin B3
chr23_+_4689626 0.15 ENSDART00000131532
glycoprotein IX (platelet)
chr11_-_36341189 0.15 ENSDART00000159752
sortilin 1a
chr22_+_37631034 0.15 ENSDART00000159016
ENSDART00000193346
proteasome 26S subunit, non-ATPase 1
chr23_-_16980213 0.14 ENSDART00000046889
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr23_-_44207349 0.14 ENSDART00000186276
zgc:158659
chr25_-_1348370 0.14 ENSDART00000154865
integrin, alpha 11b
chr8_+_28257219 0.14 ENSDART00000183749

chr7_+_5910467 0.14 ENSDART00000173232
si:ch211-113a14.22
chr3_+_19460991 0.14 ENSDART00000169124
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog a
chr11_-_35171768 0.13 ENSDART00000192896
TRAF-interacting protein
chr17_-_15201031 0.13 ENSDART00000124426
suppressor of cytokine signaling 4
chr6_-_39270851 0.13 ENSDART00000148839
Rho guanine nucleotide exchange factor (GEF) 25b
chr13_+_48359573 0.13 ENSDART00000161959
ENSDART00000165311
mutS homolog 6 (E. coli)
chr19_+_4139065 0.13 ENSDART00000172524
si:dkey-218f9.10
chr3_+_21225750 0.13 ENSDART00000139213
zgc:153968
chr6_+_21992820 0.13 ENSDART00000147507
THUMP domain containing 3
chr5_+_42400777 0.13 ENSDART00000183114

chr2_+_4146606 0.13 ENSDART00000171170
mindbomb E3 ubiquitin protein ligase 1
chr1_+_56919742 0.13 ENSDART00000152241
si:ch211-1f22.9
chr6_-_14292307 0.13 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr6_+_30689239 0.12 ENSDART00000065206
WD repeat domain 78
chr2_+_2181709 0.12 ENSDART00000092763
ENSDART00000148553
coiled-coil domain containing 13
chr21_+_4256291 0.12 ENSDART00000148138
leucine rich repeat containing 8 VRAC subunit Aa
chr10_-_40484531 0.12 ENSDART00000142464
ENSDART00000180318
trace amine associated receptor 20z
chr16_+_8695595 0.12 ENSDART00000173249
si:cabz01093077.1
chr19_+_32979331 0.12 ENSDART00000078066
spire-type actin nucleation factor 1a
chr12_+_18681477 0.11 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr13_+_40034176 0.11 ENSDART00000189797
golgin A7 family, member Bb
chr18_+_30508729 0.11 ENSDART00000185140
cytochrome c oxidase subunit IV isoform 1
chr4_+_9028819 0.11 ENSDART00000102893
aldehyde dehydrogenase 1 family, member L2
chr10_-_24759616 0.11 ENSDART00000079528
integrin-linked kinase
chr2_+_9755422 0.11 ENSDART00000018524
phosphate cytidylyltransferase 1, choline, alpha a
chr23_-_14990865 0.11 ENSDART00000147799
ndrg family member 3b
chr9_+_48219111 0.11 ENSDART00000111225
ENSDART00000145972
coiled-coil domain containing 173
chr4_-_65525733 0.11 ENSDART00000159401

chr2_+_31614533 0.11 ENSDART00000111038
ENSDART00000181311
si:ch211-106h4.6
chr19_-_1855368 0.11 ENSDART00000029646
ribosomal protein, large, P1
chr20_-_16171297 0.10 ENSDART00000012476
cytochrome c oxidase assembly factor 7
chr3_+_25825043 0.10 ENSDART00000153749
phosphoinositide-3-kinase, regulatory subunit 6b
chr9_-_52490579 0.10 ENSDART00000161667
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr2_+_33726862 0.10 ENSDART00000146745
si:dkey-31m5.5
chr1_+_8442071 0.10 ENSDART00000143547
myosin XVAb

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd4a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.2 1.7 GO:0045299 otolith mineralization(GO:0045299)
0.2 3.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 0.5 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.1 2.3 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.6 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 1.4 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.3 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 4.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 1.0 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.4 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.6 GO:0042026 protein refolding(GO:0042026)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0042560 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 1.6 GO:0046883 regulation of hormone secretion(GO:0046883)
0.0 0.8 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.2 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.4 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.6 GO:0021984 adenohypophysis development(GO:0021984) lens fiber cell differentiation(GO:0070306)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 1.0 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.4 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 1.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 3.3 GO:0060537 muscle tissue development(GO:0060537)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034515 proteasome storage granule(GO:0034515)
0.1 4.1 GO:0005861 troponin complex(GO:0005861)
0.1 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.6 GO:0031514 motile cilium(GO:0031514)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.6 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 2.3 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.8 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.2 3.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.5 GO:0016531 copper chaperone activity(GO:0016531)
0.1 1.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0043531 phosphotransferase activity, carboxyl group as acceptor(GO:0016774) ADP binding(GO:0043531)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)