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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxd9a

Z-value: 0.91

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Transcription factors associated with hoxd9a

Gene Symbol Gene ID Gene Info
ENSDARG00000059274 homeobox D9a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd9adr11_v1_chr9_-_1965727_1965727-0.056.6e-01Click!

Activity profile of hoxd9a motif

Sorted Z-values of hoxd9a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_46425262 15.31 ENSDART00000153690
sc:d0202
chr6_-_53426773 13.92 ENSDART00000162791
macrophage stimulating 1
chr13_+_17672527 13.51 ENSDART00000148269
ENSDART00000137776
catechol-O-methyltransferase domain containing 1
chr16_+_23913943 12.43 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr11_+_37201483 12.08 ENSDART00000160930
ENSDART00000173439
ENSDART00000171273
zgc:112265
chr5_+_28830643 11.86 ENSDART00000051448
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr15_+_14856307 11.07 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr22_+_37888249 9.84 ENSDART00000076082
fetuin B
chr22_-_24880824 9.40 ENSDART00000061165
vitellogenin 2
chr14_+_32430982 8.43 ENSDART00000017179
ENSDART00000123382
ENSDART00000075593
coagulation factor IXa
chr22_+_12770877 7.76 ENSDART00000044683
formimidoyltransferase cyclodeaminase
chr23_+_37482727 7.73 ENSDART00000162737
agmatine ureohydrolase (agmatinase)
chr14_+_29975268 7.25 ENSDART00000172985
cytochrome P450, family 4, subfamily V, polypeptide 7
chr24_-_38083378 6.90 ENSDART00000056381
C-reactive protein 2
chr7_-_26308098 6.58 ENSDART00000146440
ENSDART00000146935
ENSDART00000164627
zgc:77439
chr7_-_26306546 6.55 ENSDART00000140817
zgc:77439
chr3_+_1030479 6.43 ENSDART00000143449
zgc:172253
chr7_+_56577522 6.01 ENSDART00000149130
ENSDART00000149624
haptoglobin
chr21_-_42831033 5.62 ENSDART00000160998
serine/threonine kinase 10
chr17_+_20174812 5.26 ENSDART00000186628
si:ch211-248a14.8
chr15_-_32383340 5.23 ENSDART00000185632
complement component 4
chr4_+_14900042 5.04 ENSDART00000018261
aldo-keto reductase family 1, member B1 (aldose reductase)
chr6_-_58764672 4.91 ENSDART00000154322
sterol O-acyltransferase 2
chr10_+_38708099 4.75 ENSDART00000172306
transmembrane protease, serine 2
chr2_+_11031360 4.65 ENSDART00000180020
ENSDART00000145093
acyl-CoA thioesterase 11a
chr2_-_11119303 4.54 ENSDART00000135450
ENSDART00000131836
crystallin, zeta (quinone reductase)
chr25_-_30383617 4.53 ENSDART00000165342
si:ch211-93f2.1
chr25_+_23280220 4.43 ENSDART00000153940
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1
chr21_+_39963851 4.30 ENSDART00000144435
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr6_+_8626427 4.17 ENSDART00000193660
thrombospondin-type laminin G domain and EAR repeats a
chr16_+_1383914 4.10 ENSDART00000185089
ceramide synthase 2b
chr3_+_21225750 4.08 ENSDART00000139213
zgc:153968
chr6_-_7776612 3.99 ENSDART00000190269
myosin, heavy chain 9a, non-muscle
chr5_+_57480014 3.93 ENSDART00000135520
si:ch211-202f5.3
chr5_-_1963498 3.91 ENSDART00000073462
ribosomal protein, large, P0
chr19_+_2876106 3.82 ENSDART00000189309
HGH1 homolog (S. cerevisiae)
chr4_+_14899720 3.81 ENSDART00000187456
aldo-keto reductase family 1, member B1 (aldose reductase)
chr20_-_33515890 3.70 ENSDART00000159987
si:dkey-65b13.13
chr12_-_990149 3.70 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr22_-_17671348 3.70 ENSDART00000137995
tight junction protein 3
chr11_+_43431289 3.61 ENSDART00000192526
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr21_+_39941875 3.56 ENSDART00000190414
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr2_+_27855346 3.49 ENSDART00000175159
ENSDART00000192645
bucky ball
chr6_+_41191482 3.45 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr6_-_52675630 3.44 ENSDART00000083830
syndecan 4
chr23_+_7379728 3.43 ENSDART00000012194
GATA binding protein 5
chr15_-_32383529 3.36 ENSDART00000028349
complement component 4
chr23_+_2666944 3.33 ENSDART00000192861

chr22_-_16154771 3.22 ENSDART00000009464
solute carrier family 30 (zinc transporter), member 7
chr1_+_38858399 3.12 ENSDART00000165454

chr19_+_10855158 3.07 ENSDART00000172219
ENSDART00000170826
apolipoprotein Ea
chr3_+_60277300 3.01 ENSDART00000170977
SEC14-like lipid binding 1
chr22_+_1028724 2.95 ENSDART00000149625
si:ch73-352p18.4
chr16_-_28658341 2.95 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr19_-_657439 2.91 ENSDART00000167100
solute carrier family 6 (neutral amino acid transporter), member 18
chr7_-_16194952 2.84 ENSDART00000173739
bloodthirsty-related gene family, member 4
chr7_+_8358547 2.83 ENSDART00000173016
jacalin 7
chr17_-_20236228 2.76 ENSDART00000136490
ENSDART00000029380
BCL2 interacting protein 4
chr10_-_44467384 2.60 ENSDART00000186382

chr8_+_22359881 2.59 ENSDART00000187867
zgc:153631
chr11_-_3366782 2.57 ENSDART00000127982
sulfite oxidase
chr7_-_24046999 2.53 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dehydrogenase/reductase (SDR family) member 4
chr20_-_43741159 2.53 ENSDART00000192621
si:dkeyp-50f7.2
chr22_+_16555939 2.52 ENSDART00000012604
PDZK1 interacting protein 1
chr8_-_36287046 2.50 ENSDART00000162877
si:busm1-194e12.11
chr8_+_471342 2.49 ENSDART00000167205
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr13_+_29238850 2.47 ENSDART00000026000
myoferlin like
chr12_+_1286642 2.45 ENSDART00000157467
phosphatidylethanolamine N-methyltransferase
chr7_-_51953807 2.41 ENSDART00000174102
ENSDART00000145645
ENSDART00000052054
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr2_-_39558643 2.36 ENSDART00000139860
ENSDART00000145231
ENSDART00000141721
cerebellin 7
chr20_-_52902693 2.35 ENSDART00000166115
ENSDART00000161050
cathepsin Bb
chr3_+_46763745 2.35 ENSDART00000185437
protein kinase C substrate 80K-H
chr7_+_66822229 2.35 ENSDART00000112109
lymphatic vessel endothelial hyaluronic receptor 1a
chr13_+_45709380 2.34 ENSDART00000192862
si:ch211-62a1.3
chr24_-_1985007 2.34 ENSDART00000189870
par-3 family cell polarity regulator
chr2_+_11685742 2.34 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr11_-_26701611 2.31 ENSDART00000083010
acyl-CoA dehydrogenase family, member 9
chr12_+_3871452 2.29 ENSDART00000066546
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr15_+_15390882 2.27 ENSDART00000062024
carbonic anhydrase IV b
chr22_+_2959879 2.24 ENSDART00000185354
ENSDART00000063545
impact RWD domain protein
chr24_+_5912635 2.22 ENSDART00000153736
Pim proto-oncogene, serine/threonine kinase, related 63
chr24_-_25166416 2.17 ENSDART00000111552
ENSDART00000169495
pleckstrin homology-like domain, family B, member 2b
chr15_-_23793641 2.14 ENSDART00000122891
transmembrane protein 97
chr10_-_36808348 2.12 ENSDART00000099320
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr10_+_14488625 2.11 ENSDART00000026383
sigma non-opioid intracellular receptor 1
chr18_+_44849809 2.09 ENSDART00000097328
ADP-ribosylation factor GTPase activating protein 2
chr15_-_4580763 2.05 ENSDART00000008170
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr4_-_17669881 2.04 ENSDART00000066997
DNA-damage regulated autophagy modulator 1
chr21_-_11646878 2.02 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr3_+_60761811 2.01 ENSDART00000053482
TSEN54 tRNA splicing endonuclease subunit
chr8_+_39674707 2.01 ENSDART00000126301
ENSDART00000040330
protein kinase, AMP-activated, beta 1 non-catalytic subunit, b
chr21_+_39941184 2.00 ENSDART00000133604
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr10_-_14488472 2.00 ENSDART00000101298
ENSDART00000138161
galactose-1-phosphate uridylyltransferase
chr7_+_38510197 1.96 ENSDART00000173468
ENSDART00000100479
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr7_+_35068036 1.95 ENSDART00000022139
zgc:136461
chr7_-_28658143 1.93 ENSDART00000173556
adhesion G protein-coupled receptor G1
chr6_-_39727244 1.91 ENSDART00000065057
integrin, beta 7
chr3_+_12440099 1.91 ENSDART00000158060
vasorin b
chr13_-_36535128 1.88 ENSDART00000043312
serine/arginine-rich splicing factor 5a
chr12_+_19199735 1.84 ENSDART00000066393
pdgfa associated protein 1a
chr20_-_40760217 1.82 ENSDART00000101007
connexin 34.5
chr13_-_24260609 1.82 ENSDART00000138747
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr7_-_24047316 1.81 ENSDART00000184799
dehydrogenase/reductase (SDR family) member 4
chr20_-_21910043 1.80 ENSDART00000152290
ENSDART00000109084
dishevelled associated activator of morphogenesis 1b
chr2_+_11119315 1.80 ENSDART00000055737
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr23_-_26128593 1.76 ENSDART00000136855
ENSDART00000193700
ENSDART00000163984
regulator of complement activation group 2 gene 2
chr15_+_17406920 1.74 ENSDART00000081059
ribosomal protein S6 kinase b, polypeptide 1b
chr12_+_1000323 1.74 ENSDART00000054363
si:ch1073-272o11.3
chr2_+_27855102 1.73 ENSDART00000150330
bucky ball
chr24_-_21090447 1.71 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
queuine tRNA-ribosyltransferase accessory subunit 2
chr6_-_2134581 1.70 ENSDART00000175478
V-set and transmembrane domain containing 2 like
chr21_+_39941559 1.69 ENSDART00000189718
ENSDART00000160875
ENSDART00000135235
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr22_-_9736050 1.69 ENSDART00000152919
si:dkey-286j17.4
chr4_+_8680767 1.68 ENSDART00000182726
adiponectin receptor 2
chr20_-_19858936 1.65 ENSDART00000161579
protein tyrosine kinase 2 beta, b
chr2_+_49713592 1.62 ENSDART00000189624

chr17_-_43594864 1.60 ENSDART00000139980
zinc finger, FYVE domain containing 28
chr6_-_141564 1.59 ENSDART00000151245
ENSDART00000063876
sphingosine-1-phosphate receptor 5b
chr23_-_26252103 1.58 ENSDART00000160873
membrane associated guanylate kinase, WW and PDZ domain containing 3a
chr18_-_44908479 1.57 ENSDART00000169636
si:ch211-71n6.4
chr4_-_16658514 1.57 ENSDART00000133837
DENN/MADD domain containing 5B
chr5_-_9216758 1.56 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr13_-_24257631 1.55 ENSDART00000146524
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr20_+_18163821 1.55 ENSDART00000186507
aquaporin 4
chr17_+_30442518 1.54 ENSDART00000155264
lipin 1
chr6_-_34938678 1.53 ENSDART00000186689
ENSDART00000131610
SERPINE1 mRNA binding protein 1a
chr6_-_42983843 1.51 ENSDART00000130666
tumor necrosis factor receptor superfamily, member 18
chr16_+_11660839 1.51 ENSDART00000193911
ENSDART00000143683
si:dkey-250k15.10
chr19_+_47299212 1.50 ENSDART00000158262
thiopurine S-methyltransferase, tandem duplicate 1
chr2_+_10280645 1.50 ENSDART00000063996
growth arrest and DNA-damage-inducible, alpha, a
chr10_-_1276046 1.50 ENSDART00000169779
PDZ and LIM domain 5b
chr8_-_39884359 1.50 ENSDART00000131372
malectin
chr2_-_10600950 1.48 ENSDART00000160216

chr23_+_4483083 1.46 ENSDART00000092389
nucleoporin 210
chr20_+_53368611 1.45 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr16_-_16761164 1.45 ENSDART00000135872
si:dkey-27n14.1
chr9_+_21993092 1.44 ENSDART00000059693
crystallin, gamma M7
chr10_-_24784446 1.44 ENSDART00000140877
si:ch1073-15f19.2
chr10_+_14963898 1.41 ENSDART00000187363
ENSDART00000175732
si:dkey-88l16.3
chr5_-_24238733 1.41 ENSDART00000138170
phospholipid scramblase 3a
chr5_+_26686279 1.39 ENSDART00000193543
transport and golgi organization 2 homolog (Drosophila)
chr2_-_43191465 1.37 ENSDART00000025254
cAMP responsive element modulator a
chr25_-_16768078 1.37 ENSDART00000025186
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 1
chr5_-_4216324 1.36 ENSDART00000168610
si:ch211-283g2.2
chr20_+_38458084 1.36 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr15_-_14193926 1.34 ENSDART00000162707
polynucleotide kinase 3'-phosphatase
chr19_+_7810028 1.33 ENSDART00000081592
ENSDART00000140719
aquaporin 10b
chr1_+_41898919 1.32 ENSDART00000140845
si:dkey-37g12.1
chr24_-_3477103 1.32 ENSDART00000143723
isopentenyl-diphosphate delta isomerase 1
chr25_-_23526058 1.30 ENSDART00000191331
ENSDART00000062930
pleckstrin homology-like domain, family A, member 2
chr19_+_4139065 1.30 ENSDART00000172524
si:dkey-218f9.10
chr11_-_19585859 1.29 ENSDART00000165989
ataxin 7
chr21_+_35327328 1.29 ENSDART00000130626
arginyl-tRNA synthetase
chr2_+_4402765 1.27 ENSDART00000159525
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b
chr10_-_40557210 1.26 ENSDART00000135297
trace amine associated receptor 18b
chr16_+_27383717 1.26 ENSDART00000132329
ENSDART00000136256
syntaxin 17
chr12_+_30723778 1.25 ENSDART00000153291
solute carrier family 35, member F3a
chr16_-_25400257 1.24 ENSDART00000040756
zgc:136493
chr6_+_21684296 1.23 ENSDART00000057223
Ras homolog, mTORC1 binding like 1
chr8_-_38355268 1.23 ENSDART00000129597
sorbin and SH3 domain containing 3
chr5_+_45007962 1.22 ENSDART00000010786
doublesex and mab-3 related transcription factor 2a
chr17_-_45383699 1.22 ENSDART00000141182
transmembrane protein 206
chr21_-_32781612 1.22 ENSDART00000031028
CCR4-NOT transcription complex, subunit 6a
chr15_+_11825366 1.21 ENSDART00000190042
protein kinase D2
chr15_-_23699737 1.20 ENSDART00000078311
zgc:154093
chr8_+_3405612 1.19 ENSDART00000163437
zgc:112433
chr6_+_32834007 1.18 ENSDART00000157353
cylindromatosis (turban tumor syndrome), like
chr4_-_14954327 1.18 ENSDART00000182729
solute carrier family 26 (anion exchanger), member 5
chr2_+_23081402 1.18 ENSDART00000183073
major facilitator superfamily domain containing 12a
chr22_+_35205968 1.17 ENSDART00000150467
TSC22 domain family 2
chr6_-_57539141 1.16 ENSDART00000156967
itchy E3 ubiquitin protein ligase a
chr13_-_280827 1.15 ENSDART00000144819
solute carrier family 30 (zinc transporter), member 6
chr16_-_7443388 1.15 ENSDART00000017445
PR domain containing 1a, with ZNF domain
chr4_-_14954029 1.14 ENSDART00000038642
solute carrier family 26 (anion exchanger), member 5
chr8_-_36327328 1.14 ENSDART00000183333
zgc:103700
chr18_-_36066087 1.13 ENSDART00000059352
ENSDART00000145177
exosome component 5
chr5_+_38685089 1.12 ENSDART00000139743
si:dkey-58f10.10
chr11_-_4787083 1.12 ENSDART00000159425
si:ch211-63i20.3
chr25_-_13320986 1.12 ENSDART00000169238
si:ch211-194m7.8
chr14_+_33329420 1.10 ENSDART00000171090
ENSDART00000164062
sosondowah ankyrin repeat domain family d
chr5_-_66798729 1.09 ENSDART00000113077
im:7154036
chr10_+_23537576 1.09 ENSDART00000130515

chr25_+_3099073 1.09 ENSDART00000022506
RAB3A interacting protein (rabin3)-like 1
chr10_-_35410518 1.08 ENSDART00000048430
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr11_-_34065718 1.08 ENSDART00000110608
collagen, type VI, alpha 1
chr2_+_19195841 1.08 ENSDART00000163137
ENSDART00000161095
ELOVL fatty acid elongase 1a
chr17_-_14876758 1.08 ENSDART00000155857
nidogen 2a (osteonidogen)
chr1_-_17715493 1.08 ENSDART00000133027
si:dkey-256e7.8
chr2_+_42072231 1.07 ENSDART00000084517
valosin containing protein (p97)/p47 complex interacting protein 1
chr16_-_46558708 1.07 ENSDART00000128037
si:dkey-152b24.8
chr4_+_42175261 1.07 ENSDART00000162193
si:ch211-142b24.2
chr20_-_5229157 1.07 ENSDART00000114851
ENSDART00000182876
coiled-coil domain containing 85C, b
chr22_+_6084771 1.06 ENSDART00000009590
si:dkey-19a16.16
chr20_+_32406011 1.06 ENSDART00000018640
ENSDART00000137910
sorting nexin 3
chr11_+_23760470 1.06 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
neurofascin homolog (chicken) a
chr15_+_24795473 1.06 ENSDART00000139689
ENSDART00000141033
ENSDART00000100746
ENSDART00000135677
golgi SNAP receptor complex member 1
chr17_-_27419499 1.05 ENSDART00000186773
YTH N(6)-methyladenosine RNA binding protein 2
chr4_+_359970 1.04 ENSDART00000139832
transmembrane protein 181
chr5_-_23805387 1.04 ENSDART00000133805
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr3_-_46403778 1.02 ENSDART00000074422
cell death-inducing p53 target 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd9a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
2.4 7.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
2.2 11.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.6 9.4 GO:0050764 regulation of phagocytosis(GO:0050764)
0.9 5.2 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.9 3.4 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.9 3.4 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.8 2.5 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.8 4.0 GO:0061439 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.8 7.7 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.8 3.1 GO:0097242 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.7 2.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.7 2.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.6 3.6 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.6 2.3 GO:0019532 oxalate transport(GO:0019532)
0.6 2.9 GO:0006833 water transport(GO:0006833)
0.5 4.9 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.5 3.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 2.2 GO:0010447 response to acidic pH(GO:0010447) negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.4 8.2 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.4 2.0 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.4 1.9 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.4 3.7 GO:0030104 water homeostasis(GO:0030104)
0.3 1.0 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.3 1.7 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 1.0 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.3 2.9 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.3 2.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.3 2.0 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.3 23.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.3 8.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.3 1.1 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.3 1.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 0.8 GO:0070126 mitochondrial translational termination(GO:0070126)
0.3 1.3 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 1.2 GO:0043476 pigment accumulation(GO:0043476)
0.2 1.8 GO:0034475 U4 snRNA 3'-end processing(GO:0034475)
0.2 0.7 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 12.0 GO:0030282 bone mineralization(GO:0030282)
0.2 1.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.2 1.2 GO:0089700 endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.2 1.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 0.7 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.2 4.4 GO:0048844 artery morphogenesis(GO:0048844)
0.2 0.7 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 3.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 1.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 4.7 GO:0006829 zinc II ion transport(GO:0006829)
0.2 1.7 GO:0007172 signal complex assembly(GO:0007172)
0.1 15.5 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.1 0.7 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 1.3 GO:0006857 oligopeptide transport(GO:0006857)
0.1 3.2 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 1.2 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.3 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.1 GO:0015802 basic amino acid transport(GO:0015802) arginine transport(GO:0015809)
0.1 1.1 GO:0001709 cell fate determination(GO:0001709)
0.1 2.1 GO:0042574 retinal metabolic process(GO:0042574)
0.1 2.9 GO:0009636 response to toxic substance(GO:0009636)
0.1 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 2.5 GO:0007520 myoblast fusion(GO:0007520)
0.1 2.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 2.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.4 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.1 0.6 GO:0031179 peptide modification(GO:0031179)
0.1 1.0 GO:0030259 lipid glycosylation(GO:0030259)
0.1 11.8 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.1 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 3.0 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 4.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 3.4 GO:0007602 phototransduction(GO:0007602)
0.1 1.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 1.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 5.7 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 16.4 GO:0032259 methylation(GO:0032259)
0.1 1.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.5 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 2.9 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.7 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 1.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 1.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 1.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.6 GO:0035545 determination of left/right asymmetry in diencephalon(GO:0035462) determination of left/right asymmetry in nervous system(GO:0035545)
0.0 2.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 1.2 GO:0007548 sex differentiation(GO:0007548)
0.0 1.5 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 1.0 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.7 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 1.1 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 1.9 GO:0007596 blood coagulation(GO:0007596)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.7 GO:0032526 response to retinoic acid(GO:0032526)
0.0 6.4 GO:0009617 response to bacterium(GO:0009617)
0.0 0.3 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.7 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 1.1 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.9 GO:0031929 TOR signaling(GO:0031929)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.8 GO:0007292 female gamete generation(GO:0007292)
0.0 0.1 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.6 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.1 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.7 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.7 5.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.6 2.3 GO:0017177 glucosidase II complex(GO:0017177)
0.5 2.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.3 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 1.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.3 4.8 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.0 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 2.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 1.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 0.8 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.8 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.0 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 3.2 GO:0005844 polysome(GO:0005844)
0.1 1.1 GO:0030904 retromer complex(GO:0030904)
0.1 2.2 GO:0045180 basal cortex(GO:0045180)
0.1 1.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 3.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.6 GO:0071546 pi-body(GO:0071546)
0.1 3.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.0 GO:0005581 collagen trimer(GO:0005581)
0.1 3.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 5.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 4.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 4.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 1.7 GO:0005643 nuclear pore(GO:0005643)
0.0 1.1 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 41.5 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0043296 apical junction complex(GO:0043296)
0.0 1.7 GO:0005840 ribosome(GO:0005840)
0.0 1.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 23.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 12.6 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 2.4 GO:0005764 lysosome(GO:0005764)
0.0 11.7 GO:0005739 mitochondrion(GO:0005739)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.9 7.8 GO:0016841 ammonia-lyase activity(GO:0016841)
1.5 4.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.5 13.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.2 3.7 GO:0046923 ER retention sequence binding(GO:0046923)
1.2 4.9 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
1.2 3.6 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.9 7.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.8 2.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.7 11.6 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.7 4.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.7 3.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.5 1.5 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.5 13.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.5 2.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.5 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 1.3 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.4 1.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.3 1.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.3 11.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 4.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 0.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.2 2.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 3.1 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.2 1.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 1.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 2.6 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.2 0.7 GO:0070513 death domain binding(GO:0070513)
0.2 0.7 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2 2.0 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 1.3 GO:0035673 oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673) dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.2 20.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 39.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 4.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 1.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.1 GO:0034632 retinol transporter activity(GO:0034632)
0.1 1.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.1 0.7 GO:0004104 cholinesterase activity(GO:0004104)
0.1 2.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.6 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 1.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 2.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.6 GO:0034584 piRNA binding(GO:0034584)
0.1 1.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.6 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 3.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.4 GO:0004960 thromboxane receptor activity(GO:0004960)
0.1 2.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 2.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 7.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 2.0 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 1.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.1 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 1.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 8.5 GO:0004497 monooxygenase activity(GO:0004497)
0.0 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.9 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 2.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 2.2 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.6 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 4.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 10.4 GO:0008289 lipid binding(GO:0008289)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 3.5 GO:0015293 symporter activity(GO:0015293)
0.0 0.8 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 1.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.9 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 1.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.5 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.0 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 1.1 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 2.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 13.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 3.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 1.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 11.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 1.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.5 1.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 7.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 8.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.3 2.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 3.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 4.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 2.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 1.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.8 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 7.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 3.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 3.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 3.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 2.0 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.1 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors