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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for jdp2a

Z-value: 1.06

Motif logo

Transcription factors associated with jdp2a

Gene Symbol Gene ID Gene Info
ENSDARG00000040137 Jun dimerization protein 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
jdp2adr11_v1_chr17_-_50220228_502202280.698.1e-15Click!

Activity profile of jdp2a motif

Sorted Z-values of jdp2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_21832441 20.17 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
myelin basic protein a
chr7_-_13381129 12.42 ENSDART00000164326
si:ch73-119p20.1
chr9_+_38372216 11.40 ENSDART00000141895
phospholipase C, delta 4b
chr11_-_3552067 11.30 ENSDART00000163656
si:dkey-33m11.6
chr2_+_47581997 10.72 ENSDART00000112579
secretogranin II (chromogranin C), b
chr1_+_45323142 10.48 ENSDART00000132210
epithelial membrane protein 1
chr1_+_12766351 10.18 ENSDART00000165785
protocadherin 10a
chr12_+_7497882 9.17 ENSDART00000134608
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr1_+_31113951 8.66 ENSDART00000129362
eukaryotic translation elongation factor 1 alpha 1b
chr2_+_47582681 8.63 ENSDART00000187579
secretogranin II (chromogranin C), b
chr10_+_4499943 8.58 ENSDART00000125299
polo-like kinase 2a (Drosophila)
chr1_-_45647846 8.55 ENSDART00000186881

chr25_+_30196039 8.35 ENSDART00000005299
hydroxysteroid (17-beta) dehydrogenase 12a
chr7_+_48460239 8.16 ENSDART00000052113
leucine rich repeat and Ig domain containing 1b
chr14_-_34044369 8.14 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr6_+_40354424 7.98 ENSDART00000047416
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr5_+_34549845 7.96 ENSDART00000139317
allograft inflammatory factor 1-like
chr7_-_52963493 7.92 ENSDART00000052029
cocaine- and amphetamine-regulated transcript 3
chr14_+_34486629 7.61 ENSDART00000131861
thymosin beta 2
chr25_+_21324588 7.39 ENSDART00000151842
leucine rich repeat neuronal 3a
chr18_+_21408794 7.16 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr7_+_23577723 7.01 ENSDART00000049885
si:dkey-172j4.3
chr23_+_4253957 6.96 ENSDART00000008761
ADP-ribosylation factor-like 6 interacting protein 5b
chr1_+_45323400 6.92 ENSDART00000148906
ENSDART00000132366
epithelial membrane protein 1
chr2_+_30379650 6.89 ENSDART00000129542
cysteine-rich secretory protein LCCL domain containing 1b
chr24_-_24849091 6.83 ENSDART00000133649
ENSDART00000038290
corticotropin releasing hormone b
chr20_-_40319890 6.83 ENSDART00000075112
clavesin 2
chr4_-_69189894 6.77 ENSDART00000169596
si:ch211-209j12.1
chr3_+_24986145 6.68 ENSDART00000055428
chromobox homolog 7a
chr19_-_103289 6.56 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr17_-_7861219 6.33 ENSDART00000148604
spectrin repeat containing, nuclear envelope 1b
chr13_-_21701323 6.14 ENSDART00000164112
si:dkey-191g9.7
chr7_+_20587506 6.07 ENSDART00000172416
ENSDART00000170633
si:dkey-19b23.7
chr14_+_24935131 6.05 ENSDART00000170871
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr8_-_14375890 5.89 ENSDART00000090306
xenotropic and polytropic retrovirus receptor 1a
chr5_-_14564878 5.81 ENSDART00000160511
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr24_-_24797455 5.57 ENSDART00000138741
phosphodiesterase 7A
chr8_-_22288004 5.52 ENSDART00000100042
si:ch211-147a11.3
chr10_-_34772211 5.49 ENSDART00000145450
ENSDART00000134307
doublecortin-like kinase 1a
chr5_+_59534286 5.48 ENSDART00000189341
GTF2I repeat domain containing 1
chr3_+_30921246 5.35 ENSDART00000076850
claudin i
chr10_+_45128375 5.21 ENSDART00000164805
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr1_-_22861348 5.11 ENSDART00000139412
si:dkey-92j12.6
chr8_+_24854600 5.07 ENSDART00000156570
solute carrier family 6 (neutral amino acid transporter), member 17
chr12_+_20336070 4.98 ENSDART00000066385
zgc:163057
chr7_+_7019911 4.80 ENSDART00000172421
RNA binding motif protein 14b
chr19_-_5805923 4.78 ENSDART00000134340
si:ch211-264f5.8
chr2_-_32738535 4.74 ENSDART00000135293
nuclear receptor binding protein 2a
chr18_-_13360106 4.73 ENSDART00000091512
c-Maf inducing protein
chr17_+_33495194 4.72 ENSDART00000033691
parathyroid hormone 2
chr7_+_23875269 4.68 ENSDART00000101406
RAB39B, member RAS oncogene family b
chr7_+_38770167 4.66 ENSDART00000190827
Rho GTPase activating protein 1
chr3_+_31177972 4.54 ENSDART00000185954
C-type lectin domain containing 19A
chr6_-_33685325 4.51 ENSDART00000181883
microtubule associated serine/threonine kinase 2
chr8_+_44549290 4.42 ENSDART00000160801
si:dkey-220o5.5
chr1_+_2190714 4.31 ENSDART00000132126
muscleblind-like splicing regulator 2
chr7_+_528593 4.31 ENSDART00000091955
neurexin 2b
chr8_-_22288258 4.28 ENSDART00000140978
ENSDART00000100046
si:ch211-147a11.3
chr24_-_21404367 4.25 ENSDART00000152093
ATPase phospholipid transporting 8A2
chr12_+_4971515 4.24 ENSDART00000161076
Rho GTPase activating protein 27
chr24_+_41940299 4.22 ENSDART00000022349
erythrocyte membrane protein band 4.1-like 3a
chr19_+_16595332 4.08 ENSDART00000151254
protein tyrosine phosphatase, receptor type, U, a
chr14_+_20900989 4.06 ENSDART00000106209
zgc:162941
chr15_-_33834577 3.98 ENSDART00000163354
matrix metallopeptidase 13b
chr18_+_16750080 3.98 ENSDART00000136320
ring finger protein 141
chr4_+_68087932 3.96 ENSDART00000150494
zinc finger protein 1096
chr5_+_17624463 3.90 ENSDART00000183869
ENSDART00000081064
fibrosin-like 1
chr22_-_24297510 3.87 ENSDART00000163297
si:ch211-117l17.6
chr15_-_47838391 3.86 ENSDART00000180337
kelch repeat and BTB (POZ) domain containing 3
chr15_+_24704798 3.82 ENSDART00000192470
si:dkey-151p21.7
chr22_+_19247255 3.82 ENSDART00000144053
si:dkey-21e2.10
chr8_+_10561922 3.81 ENSDART00000133348
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5-like
chr3_+_20156956 3.79 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr21_-_2248239 3.78 ENSDART00000169448
si:ch73-299h12.1
chr12_+_29173523 3.64 ENSDART00000153212
adhesion G protein-coupled receptor A1a
chr3_+_7617353 3.60 ENSDART00000165551
zgc:109949
chr10_+_37145007 3.56 ENSDART00000131777
CUE domain containing 1a
chr1_+_52518176 3.46 ENSDART00000003278
tachykinin receptor 3-like
chr17_+_12942021 3.38 ENSDART00000192514
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
chr22_+_9862243 3.30 ENSDART00000105942
si:dkey-253d23.3
chr4_-_38421217 3.27 ENSDART00000164517
szinc finger protein 1092
chr19_-_7495006 3.21 ENSDART00000148836
regulatory factor X, 5
chr6_+_55428924 3.19 ENSDART00000018270
nuclear receptor coactivator 5
chr2_+_47582488 3.18 ENSDART00000149967
secretogranin II (chromogranin C), b
chr12_+_28117365 3.07 ENSDART00000066290
urotensin 2 receptor
chr3_+_39922602 3.06 ENSDART00000193937
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr2_+_9821757 3.02 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr14_-_6936731 3.01 ENSDART00000162196
CDC-like kinase 4a
chr23_-_37514493 2.99 ENSDART00000083267
DnaJ (Hsp40) homolog, subfamily C, member 16
chr3_-_45250924 2.97 ENSDART00000109017
ubiquitin specific peptidase 31
chr15_+_25489406 2.93 ENSDART00000162482
zgc:152863
chr17_+_41302660 2.93 ENSDART00000059480
fos-like antigen 2
chr21_+_25765734 2.92 ENSDART00000021664
claudin b
chr12_-_35386910 2.89 ENSDART00000153453
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr11_+_13630107 2.85 ENSDART00000172220
si:ch211-1a19.3
chr9_-_30346279 2.84 ENSDART00000089488
synaptotagmin-like 5
chr6_-_8295657 2.83 ENSDART00000185135
solute carrier family 44 (choline transporter), member 2
chr24_-_21973163 2.81 ENSDART00000131406
acyl-CoA thioesterase 9, tandem duplicate 1
chr9_+_33154841 2.80 ENSDART00000132465
dopey family member 2
chr24_-_21973365 2.79 ENSDART00000081204
ENSDART00000030592
acyl-CoA thioesterase 9, tandem duplicate 1
chr25_-_173165 2.77 ENSDART00000193594

chr11_+_13629528 2.76 ENSDART00000186509
si:ch211-1a19.3
chr4_+_54899568 2.76 ENSDART00000162786
si:dkey-56m15.8
chr18_-_19095141 2.71 ENSDART00000090962
ENSDART00000090922
DENN/MADD domain containing 4A
chr24_+_17140938 2.71 ENSDART00000149134
MLLT10, histone lysine methyltransferase DOT1L cofactor
chr8_+_43053519 2.71 ENSDART00000147178
prion protein a
chr23_+_29570386 2.66 ENSDART00000193192
leucine zipper and CTNNBIP1 domain containing
chr22_+_16320076 2.65 ENSDART00000164161
oxysterol binding protein-like 1A
chr3_+_33440615 2.62 ENSDART00000146005
GTP binding protein 1
chr13_+_30421472 2.61 ENSDART00000143569
zinc finger, MIZ-type containing 1a
chr12_-_17147473 2.59 ENSDART00000106035
STAM binding protein-like 1
chr22_+_17399124 2.58 ENSDART00000145769
RAB GTPase activating protein 1-like
chr19_-_21716593 2.53 ENSDART00000155126
zinc finger protein 516
chr11_-_25324534 2.52 ENSDART00000158598
si:ch211-232b12.5
chr21_-_18824434 2.51 ENSDART00000156333
si:dkey-112m2.1
chr24_-_32665283 2.48 ENSDART00000038364
carbonic anhydrase II
chr6_+_11250316 2.46 ENSDART00000137122
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr19_-_36675023 2.46 ENSDART00000132471
CUB and Sushi multiple domains 2
chr16_+_42829735 2.45 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr2_-_23391266 2.44 ENSDART00000159048
influenza virus NS1A binding protein b
chr23_-_1017428 2.43 ENSDART00000110588
ENSDART00000183158
cadherin 26, tandem duplicate 1
chr20_+_9683994 2.42 ENSDART00000053831
prostaglandin E receptor 2b (subtype EP2)
chr2_+_9822319 2.41 ENSDART00000144078
ENSDART00000144371
annexin A13, like
chr4_-_73299225 2.41 ENSDART00000174178
ENSDART00000174198
si:cabz01021430.2
chr8_+_25900049 2.39 ENSDART00000124300
ENSDART00000127618
ENSDART00000024009
ras homolog gene family, member Ab
chr7_+_22688781 2.37 ENSDART00000173509
UDP glucuronosyltransferase 5 family, polypeptide G1
chr23_-_1017605 2.36 ENSDART00000138290
cadherin 26, tandem duplicate 1
chr1_+_51312752 2.36 ENSDART00000063938
microtubule associated serine/threonine kinase 1a
chr9_+_32358514 2.32 ENSDART00000144608
phospholipase C like 1
chr14_+_24934736 2.31 ENSDART00000191821
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr7_-_19369002 2.31 ENSDART00000165680
netrin 4
chr25_-_18330503 2.30 ENSDART00000104496
dual specificity phosphatase 6
chr14_+_20156477 2.30 ENSDART00000123434
fragile X mental retardation 1
chr16_+_13855039 2.27 ENSDART00000113764
ENSDART00000143983
zgc:174888
chr11_-_22371105 2.21 ENSDART00000146873
transmembrane protein 183A
chr20_+_23173710 2.21 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr6_+_49901465 2.21 ENSDART00000023515
charged multivesicular body protein 4Ba
chr3_+_24197934 2.13 ENSDART00000055609
activating transcription factor 4b
chr22_-_5839686 2.13 ENSDART00000145406
si:rp71-36a1.5
chr2_-_48356787 2.11 ENSDART00000098004
period circadian clock 2
chr3_-_27646070 2.04 ENSDART00000122031
ENSDART00000151027
si:ch211-157c3.4
chr19_-_38539670 2.04 ENSDART00000136775
collagen, type XVI, alpha 1
chr2_-_37837472 2.04 ENSDART00000165347
methyltransferase like 17
chr21_+_3093419 2.03 ENSDART00000162520
SHC adaptor protein 3
chr14_+_6287871 2.01 ENSDART00000105344
TBC1 domain family, member 2
chr10_+_35422802 2.00 ENSDART00000147303
HERV-H LTR-associating 2a, tandem duplicate 1
chr4_+_45274792 1.95 ENSDART00000150295
zinc finger protein 1138
chr7_-_30174882 1.92 ENSDART00000110409
FERM domain containing 5
chr21_-_2172924 1.92 ENSDART00000169262
zgc:163077
chr3_-_48259289 1.91 ENSDART00000160717
zinc finger protein 750
chr1_-_35694978 1.91 ENSDART00000136157
si:dkey-27h10.2
chr5_+_20035284 1.90 ENSDART00000191808
small G protein signaling modulator 1a
chr3_-_61185746 1.89 ENSDART00000028219
parvalbumin 4
chr2_-_15362923 1.88 ENSDART00000166926
olfactomedin 3b
chr9_+_2499627 1.88 ENSDART00000160782
WAS/WASL interacting protein family, member 1a
chr24_-_5691956 1.87 ENSDART00000189112
deleted in autism 1b
chr1_-_54765262 1.87 ENSDART00000150362
si:ch211-197k17.3
chr14_+_6615564 1.86 ENSDART00000139292
si:dkeyp-44a8.2
chr7_-_60351876 1.83 ENSDART00000098563
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr16_-_12984631 1.79 ENSDART00000184863
calcium channel, voltage-dependent, gamma subunit 7b
chr12_-_7639120 1.78 ENSDART00000126712
ENSDART00000126219
coiled-coil domain containing 6b
chr14_+_49382180 1.77 ENSDART00000158329
TNFAIP3 interacting protein 1
chr4_+_58057168 1.73 ENSDART00000161097
si:dkey-57k17.1
chr1_+_46598764 1.72 ENSDART00000053240
calcium binding protein 39-like
chr22_+_19405517 1.70 ENSDART00000138245
ENSDART00000155144
si:dkey-78l4.2
chr20_-_35512932 1.68 ENSDART00000137690
adhesion G protein-coupled receptor F3b
chr21_-_2173300 1.67 ENSDART00000172276
zgc:163077
chr22_+_9862466 1.66 ENSDART00000146864
si:dkey-253d23.3
chr16_+_23403602 1.61 ENSDART00000159848
S100 calcium binding protein W
chr5_+_22393501 1.61 ENSDART00000185276
si:dkey-27p18.7
chr20_+_32478151 1.57 ENSDART00000145269
osteopetrosis associated transmembrane protein 1
chr16_+_37876779 1.48 ENSDART00000140148
si:ch211-198c19.1
chr3_+_45401472 1.48 ENSDART00000156693
BAI1-associated protein 3
chr4_-_56157199 1.47 ENSDART00000169806
si:ch211-207e19.15
chr19_-_31035155 1.47 ENSDART00000161882
basic leucine zipper and W2 domains 2
chr12_+_47280839 1.46 ENSDART00000187574
ryanodine receptor 2
chr22_-_26595027 1.44 ENSDART00000184162

chr19_+_33701366 1.43 ENSDART00000162517
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_44746723 1.42 ENSDART00000041806
acyl-CoA synthetase medium chain family member 3
chr11_+_2416064 1.41 ENSDART00000067117
ubiquitin-conjugating enzyme E2 variant 1
chr8_+_20037368 1.40 ENSDART00000029175
ENSDART00000170792
FCH domain only 1
chr4_-_77267787 1.37 ENSDART00000190346
zgc:174310
chrM_+_8894 1.32 ENSDART00000093611
ATP synthase 8, mitochondrial
chr5_-_69523816 1.26 ENSDART00000112692
si:ch211-157p22.10
chr12_+_23371542 1.26 ENSDART00000078896
WW domain containing adaptor with coiled-coil a
chr2_+_21229909 1.24 ENSDART00000046127
vasoactive intestinal peptide receptor 1a
chr22_+_19220459 1.24 ENSDART00000163070
si:dkey-21e2.7
chr1_-_11689525 1.20 ENSDART00000090689
BRCA1-associated ATM activator 1
chr1_+_52137528 1.16 ENSDART00000007079
ENSDART00000074265
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr15_-_13254480 1.15 ENSDART00000190499
zgc:172282
chr3_+_35498119 1.12 ENSDART00000178963
trinucleotide repeat containing 6a
chr10_-_32877348 1.10 ENSDART00000018977
ENSDART00000133421
RAB guanine nucleotide exchange factor (GEF) 1
chr15_+_847077 1.10 ENSDART00000188586
si:dkey-7i4.5
chr4_-_69550757 1.10 ENSDART00000168344
zinc finger protein 1101
chr13_+_22964868 1.07 ENSDART00000142129
tachykinin receptor 2
chr7_+_5529967 1.04 ENSDART00000142709
si:dkeyp-67a8.4
chr22_+_16497670 1.04 ENSDART00000014330
immediate early response 5
chr3_-_39648021 1.03 ENSDART00000055171
GRB2-related adaptor protein a
chr4_+_7822773 1.02 ENSDART00000171391
si:ch1073-67j19.2
chr11_-_24458786 1.01 ENSDART00000089713
matrix-remodelling associated 8a

Network of associatons between targets according to the STRING database.

First level regulatory network of jdp2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0035902 response to immobilization stress(GO:0035902)
1.7 5.1 GO:0015824 proline transport(GO:0015824)
1.6 6.6 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
1.4 4.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.0 8.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
1.0 7.2 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
1.0 7.9 GO:0008343 adult feeding behavior(GO:0008343)
0.9 4.5 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.8 7.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.7 2.8 GO:0015871 choline transport(GO:0015871)
0.6 4.5 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.6 2.5 GO:0015670 carbon dioxide transport(GO:0015670)
0.6 10.2 GO:0097324 melanocyte migration(GO:0097324)
0.5 22.5 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.5 8.1 GO:0001964 startle response(GO:0001964)
0.5 2.4 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.5 4.2 GO:1904861 excitatory synapse assembly(GO:1904861)
0.4 8.0 GO:0097178 ruffle assembly(GO:0097178)
0.4 2.3 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.4 2.9 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.4 2.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.3 8.0 GO:0015701 bicarbonate transport(GO:0015701)
0.3 2.4 GO:0044319 wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505) skeletal muscle satellite cell migration(GO:1902766)
0.3 2.3 GO:0060420 regulation of heart growth(GO:0060420)
0.3 10.3 GO:0007340 acrosome reaction(GO:0007340)
0.3 7.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 2.3 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.3 3.1 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956) positive regulation of regulated secretory pathway(GO:1903307)
0.3 6.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 2.5 GO:0044805 late nucleophagy(GO:0044805)
0.2 5.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.2 5.0 GO:0015669 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.2 7.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 4.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 6.8 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2 1.3 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.2 5.9 GO:0006817 phosphate ion transport(GO:0006817)
0.2 0.4 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 2.0 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.2 2.5 GO:0090279 regulation of calcium ion import(GO:0090279)
0.2 8.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.2 5.2 GO:0045332 phospholipid translocation(GO:0045332)
0.1 5.2 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 7.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 0.7 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.1 2.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 4.0 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 2.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 8.2 GO:0021549 cerebellum development(GO:0021549)
0.1 1.8 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1 0.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 5.4 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 0.3 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.1 2.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 8.2 GO:0042552 myelination(GO:0042552)
0.1 4.2 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.3 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544) negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 2.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 2.3 GO:0070831 basement membrane assembly(GO:0070831)
0.1 5.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 2.9 GO:0072114 pronephros morphogenesis(GO:0072114)
0.1 1.1 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 6.7 GO:0051051 negative regulation of transport(GO:0051051)
0.1 1.4 GO:0006301 postreplication repair(GO:0006301)
0.1 7.0 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 4.2 GO:0006414 translational elongation(GO:0006414)
0.1 0.2 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:0071376 neutrophil homeostasis(GO:0001780) response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 5.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 6.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 4.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 4.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 1.0 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 1.2 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 1.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 2.3 GO:0030048 actin filament-based movement(GO:0030048)
0.0 4.8 GO:0071772 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 4.4 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.3 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 2.9 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 4.3 GO:0006887 exocytosis(GO:0006887)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0030878 thyroid gland development(GO:0030878)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 20.2 GO:0043209 myelin sheath(GO:0043209)
0.6 2.3 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.6 4.5 GO:0097225 sperm midpiece(GO:0097225)
0.5 8.1 GO:0031209 SCAR complex(GO:0031209)
0.4 5.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 6.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 22.5 GO:0030141 secretory granule(GO:0030141)
0.2 2.9 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 1.4 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.2 8.0 GO:0032587 ruffle membrane(GO:0032587)
0.2 2.2 GO:0000815 ESCRT III complex(GO:0000815)
0.1 3.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 2.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.1 6.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.8 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 2.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 8.6 GO:0000922 spindle pole(GO:0000922)
0.1 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 2.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 3.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 4.8 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 8.1 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 10.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 3.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 4.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 4.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.0 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 6.7 GO:0009986 cell surface(GO:0009986)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 3.5 GO:0005768 endosome(GO:0005768)
0.0 1.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.4 8.4 GO:0030331 estrogen receptor binding(GO:0030331)
1.3 20.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.0 8.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
1.0 4.1 GO:0003796 lysozyme activity(GO:0003796)
0.7 4.4 GO:0042169 SH2 domain binding(GO:0042169)
0.7 2.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.6 4.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.6 8.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.5 3.8 GO:0005035 death receptor activity(GO:0005035)
0.5 3.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.4 3.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 15.1 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.4 5.0 GO:0031720 haptoglobin binding(GO:0031720)
0.4 7.6 GO:0003785 actin monomer binding(GO:0003785)
0.4 5.7 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.3 8.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.3 2.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 6.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 7.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 4.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.3 2.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 5.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 5.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 1.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 7.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 8.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 2.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 4.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.9 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 2.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.4 GO:0016408 C-acyltransferase activity(GO:0016408)
0.1 2.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 4.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 5.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.2 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 1.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 9.9 GO:0000287 magnesium ion binding(GO:0000287)
0.1 2.7 GO:0031491 nucleosome binding(GO:0031491)
0.1 2.3 GO:0045182 translation regulator activity(GO:0045182)
0.1 2.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 1.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0035258 steroid hormone receptor binding(GO:0035258)
0.0 4.7 GO:0005179 hormone activity(GO:0005179)
0.0 2.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 12.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 8.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 21.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.8 GO:0016247 channel regulator activity(GO:0016247)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 2.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 11.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 3.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 10.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 2.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 2.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 2.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 11.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 8.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 4.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 3.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 2.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 3.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis