Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for klf3+klf8

Z-value: 0.82

Motif logo

logo of

Transcription factors associated with klf3+klf8

Gene Symbol Gene ID Gene Info
klf3
ENSDARG00000015495 Kruppel-like factor 3 (basic)
klf8
ENSDARG00000060661 Kruppel-like factor 8
klf3
ENSDARG00000114143 Kruppel-like factor 3 (basic)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf8dr11_v1_chr21_+_38033226_38033226-0.764.4e-19Click!
klf3dr11_v1_chr1_-_18615063_18615063-0.037.5e-01Click!

Activity profile of klf3+klf8 motif

Sorted Z-values of klf3+klf8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_22797959 13.78 ENSDART00000183269
pcolcea
procollagen C-endopeptidase enhancer a
chr18_+_5549672 12.17 ENSDART00000184970
nnt2
nicotinamide nucleotide transhydrogenase 2
chr2_-_35566938 10.46 ENSDART00000029006
ENSDART00000077178
ENSDART00000125298
tnn
tenascin N
chr11_+_37278457 7.78 ENSDART00000188946
creld1a
cysteine-rich with EGF-like domains 1a
chr24_-_40668208 7.13 ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr24_-_40667800 6.91 ENSDART00000169315
smyhc1
slow myosin heavy chain 1
chr1_-_44940830 6.80 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
tmem176
transmembrane protein 176
chr3_-_1190132 5.83 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr20_-_54377933 5.68 ENSDART00000182664
entpd5b
ectonucleoside triphosphate diphosphohydrolase 5b
chr5_-_24174956 5.46 ENSDART00000137631
si:ch211-137i24.10
si:ch211-137i24.10
chr18_-_46010 5.29 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr18_+_54354 5.28 ENSDART00000097163
zgc:158482
zgc:158482
chr3_+_55093581 4.86 ENSDART00000101709
hbaa2
hemoglobin, alpha adult 2
chr24_-_14212521 4.80 ENSDART00000130825
xkr9
XK, Kell blood group complex subunit-related family, member 9
chr25_+_37435720 4.76 ENSDART00000164390
chmp1a
charged multivesicular body protein 1A
chr21_+_11244068 4.65 ENSDART00000163432
arid6
AT-rich interaction domain 6
chr16_+_23978978 4.46 ENSDART00000058964
ENSDART00000135084
apoa2
apolipoprotein A-II
chr9_-_56459660 4.35 ENSDART00000162771
ubxn4
UBX domain protein 4
chr18_-_45617146 4.26 ENSDART00000146543
wt1b
wilms tumor 1b
chr15_+_28410664 4.15 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
pitpnaa
phosphatidylinositol transfer protein, alpha a
chr1_+_57235896 4.12 ENSDART00000152621
si:dkey-27j5.7
si:dkey-27j5.7
chr22_-_30948457 4.00 ENSDART00000139887
ssuh2.1
ssu-2 homolog, tandem duplicate 1
chr20_+_54356272 3.89 ENSDART00000145735
znf410
zinc finger protein 410
chr9_-_56420087 3.83 ENSDART00000112016
actr3
ARP3 actin related protein 3 homolog
chr20_-_52928541 3.78 ENSDART00000162812
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr24_+_37461457 3.75 ENSDART00000165775
nlrc3
NLR family, CARD domain containing 3
chr20_-_52902693 3.60 ENSDART00000166115
ENSDART00000161050
ctsbb
cathepsin Bb
chr21_-_35832548 3.53 ENSDART00000180840
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr8_-_30204650 3.47 ENSDART00000133209
zgc:162939
zgc:162939
chr15_-_5580093 3.45 ENSDART00000143726
wdr62
WD repeat domain 62
chr12_+_34273240 3.38 ENSDART00000037904
socs3b
suppressor of cytokine signaling 3b
chr1_-_49434798 3.15 ENSDART00000150842
ENSDART00000150789
ATP5MD
si:dkeyp-80c12.10
chr3_+_1179601 3.08 ENSDART00000173378
triobpb
TRIO and F-actin binding protein b
chr21_-_29197700 3.04 ENSDART00000172614
si:ch211-57b15.2
si:ch211-57b15.2
chr21_+_27448856 2.91 ENSDART00000100784
cfbl
complement factor b-like
chr24_+_81527 2.87 ENSDART00000192139
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr22_+_1006573 2.87 ENSDART00000123458
pparda
peroxisome proliferator-activated receptor delta a
chr18_-_24988645 2.85 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr7_+_35229805 2.66 ENSDART00000173911
tppp3
tubulin polymerization-promoting protein family member 3
chr20_+_48129759 2.51 ENSDART00000148494
tram2
translocation associated membrane protein 2
chr6_+_120181 2.45 ENSDART00000151209
ENSDART00000185930
cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr25_+_16731802 2.44 ENSDART00000188715
BX004976.1

chr10_+_15106808 2.41 ENSDART00000141588
scpp8
secretory calcium-binding phosphoprotein 8
chr7_+_35229645 2.34 ENSDART00000144327
tppp3
tubulin polymerization-promoting protein family member 3
chr8_-_3413139 2.32 ENSDART00000182673
ENSDART00000166741
ENSDART00000169430
ENSDART00000170478
FUT9 (1 of many)
FUT9 (1 of many)
fut9b
zgc:103510
zgc:165519
fucosyltransferase 9b
chr10_+_15025006 2.26 ENSDART00000145192
ENSDART00000140084
si:dkey-88l16.5
si:dkey-88l16.5
chr21_-_280769 2.24 ENSDART00000157753
plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr22_-_3275888 2.23 ENSDART00000164743
si:zfos-943e10.1
si:zfos-943e10.1
chr13_-_50567658 2.21 ENSDART00000132281
blnk
B cell linker
chr21_+_21811867 2.19 ENSDART00000185752
neu3.4
sialidase 3 (membrane sialidase), tandem duplicate 4
chr12_+_48851381 2.16 ENSDART00000187241
ENSDART00000187796
dlg5b.1
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr12_+_19030391 2.14 ENSDART00000153927
si:ch73-139e5.2
si:ch73-139e5.2
chr17_+_20569806 2.10 ENSDART00000113936
SAMD8
zgc:162183
chr2_-_54639964 2.05 ENSDART00000100103
acss2l
acyl-CoA synthetase short chain family member 2 like
chr20_-_39391492 2.01 ENSDART00000184886
si:dkey-217m5.8
si:dkey-217m5.8
chr17_-_24353462 1.98 ENSDART00000191021
wdpcp
WD repeat containing planar cell polarity effector
chr3_-_32927516 1.96 ENSDART00000140117
aoc2
amine oxidase, copper containing 2
chr9_+_56194410 1.94 ENSDART00000168530
LO018176.1

chr7_-_2039060 1.93 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr23_-_4930229 1.89 ENSDART00000189456
ngfa
nerve growth factor a (beta polypeptide)
chr3_-_15444396 1.88 ENSDART00000104361
si:dkey-56d12.4
si:dkey-56d12.4
chr22_+_23359369 1.83 ENSDART00000170886
dennd1b
DENN/MADD domain containing 1B
chr7_-_1163829 1.77 ENSDART00000181937
CT030017.1

chr19_+_164013 1.77 ENSDART00000167379
carmil1
capping protein regulator and myosin 1 linker 1
chr12_-_14143344 1.76 ENSDART00000152742
buc2l
bucky ball 2-like
chr6_-_52757276 1.70 ENSDART00000159154
AL954861.2

chr25_-_28587896 1.69 ENSDART00000111908
si:dkeyp-67e1.6
si:dkeyp-67e1.6
chr25_-_36370292 1.68 ENSDART00000152766
CR354435.1
Histone H2B 1/2
chr2_+_10007113 1.67 ENSDART00000155213
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr22_-_5051689 1.66 ENSDART00000113521
matk
megakaryocyte-associated tyrosine kinase
chr8_-_1973220 1.65 ENSDART00000184435
si:dkey-178e17.1
si:dkey-178e17.1
chr6_-_39344259 1.65 ENSDART00000104074
zgc:158846
zgc:158846
chr1_-_53407087 1.59 ENSDART00000157910
elmod2
ELMO/CED-12 domain containing 2
chr7_+_5968225 1.41 ENSDART00000083397
zgc:165555
zgc:165555
chr7_+_4624926 1.39 ENSDART00000137387
si:dkey-83f18.6
si:dkey-83f18.6
chr25_+_37348730 1.36 ENSDART00000156639
pamr1
peptidase domain containing associated with muscle regeneration 1
chr6_+_46258866 1.34 ENSDART00000134584
zgc:162324
zgc:162324
chr12_+_34763795 1.32 ENSDART00000153097
slc38a10
solute carrier family 38, member 10
chr16_-_50918908 1.32 ENSDART00000108744
CU855821.1

chr6_+_41181869 1.26 ENSDART00000002046
opn1mw1
opsin 1 (cone pigments), medium-wave-sensitive, 1
chr19_+_19786117 1.24 ENSDART00000167757
ENSDART00000163546
hoxa1a
homeobox A1a
chr13_-_992458 1.21 ENSDART00000114655
BFSP1
beaded filament structural protein 1
chr19_+_7847920 1.16 ENSDART00000132454
si:dkeyp-85e10.1
si:dkeyp-85e10.1
chr13_-_40238813 1.13 ENSDART00000044963
loxl4
lysyl oxidase-like 4
chr6_+_4084739 1.06 ENSDART00000087661
sema5bb
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb
chr18_+_5618368 1.03 ENSDART00000159945
ulk3
unc-51 like kinase 3
chr2_-_58900077 1.03 ENSDART00000183362
ENSDART00000190274
mau2
MAU2 sister chromatid cohesion factor
chr9_+_18576047 0.93 ENSDART00000145174
lacc1
laccase (multicopper oxidoreductase) domain containing 1
chr19_-_35450857 0.89 ENSDART00000179357
anln
anillin, actin binding protein
chr4_+_54618332 0.88 ENSDART00000171824
si:ch211-227e10.2
si:ch211-227e10.2
chr23_-_1017605 0.87 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr23_-_44233408 0.86 ENSDART00000149318
ENSDART00000085528
zgc:158659
zgc:158659
chr6_-_57655030 0.83 ENSDART00000155438
cbfa2t2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr20_-_39391833 0.82 ENSDART00000135149
si:dkey-217m5.8
si:dkey-217m5.8
chr4_+_50401133 0.79 ENSDART00000150644
si:dkey-156k2.7
si:dkey-156k2.7
chr6_+_41186320 0.73 ENSDART00000025241
opn1mw2
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr9_-_11551608 0.72 ENSDART00000128629
fev
FEV (ETS oncogene family)
chr17_+_15559046 0.72 ENSDART00000187126
bach2a
BTB and CNC homology 1, basic leucine zipper transcription factor 2a
chr11_-_31146808 0.66 ENSDART00000172781
si:cabz01069582.1
si:cabz01069582.1
chr4_+_64562090 0.65 ENSDART00000188810
si:ch211-223a21.3
si:ch211-223a21.3
chr13_+_681628 0.65 ENSDART00000016604
abcc2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr11_+_45461419 0.64 ENSDART00000173424
sos1
son of sevenless homolog 1 (Drosophila)
chr1_-_59571758 0.62 ENSDART00000193546
ENSDART00000167087
wfikkn1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr23_-_1017428 0.61 ENSDART00000110588
ENSDART00000183158
cdh26.1
cadherin 26, tandem duplicate 1
chr10_-_18492617 0.57 ENSDART00000179936
ENSDART00000193799
ENSDART00000193198
si:dkey-28o19.1
si:dkey-28o19.1
chr18_+_814328 0.57 ENSDART00000157801
ENSDART00000188492
ENSDART00000184489
fam219b
family with sequence similarity 219, member B
chr4_+_53976731 0.43 ENSDART00000165813
si:ch211-249c2.1
si:ch211-249c2.1
chr4_-_74109792 0.41 ENSDART00000174320
RAB21
zgc:154045
chr8_-_34762163 0.39 ENSDART00000114080
setd1bb
SET domain containing 1B, b
chr9_-_12760323 0.35 ENSDART00000146265
myo10l3
myosin X-like 3
chr5_-_69041102 0.32 ENSDART00000161561
ank1a
ankyrin 1, erythrocytic a
chr22_-_8594846 0.25 ENSDART00000081690
ENSDART00000192241
si:ch73-27e22.1
si:ch73-27e22.1
chr16_-_23471387 0.23 ENSDART00000180899
CR533578.1

chr7_-_19600181 0.11 ENSDART00000100757
oxa1l
oxidase (cytochrome c) assembly 1-like
chr7_-_67316903 0.01 ENSDART00000159408
psmd7
proteasome 26S subunit, non-ATPase 7

Network of associatons between targets according to the STRING database.

First level regulatory network of klf3+klf8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.2 GO:0006740 NADPH regeneration(GO:0006740)
2.0 14.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
1.8 5.3 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.0 2.9 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.6 1.8 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.6 2.2 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.5 3.8 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.4 4.8 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.4 1.7 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.4 3.1 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 4.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.3 1.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.3 2.0 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.3 5.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.3 2.9 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.3 5.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.3 3.5 GO:0007525 somatic muscle development(GO:0007525)
0.3 2.5 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2 4.9 GO:0015671 oxygen transport(GO:0015671)
0.2 0.9 GO:0008356 asymmetric cell division(GO:0008356)
0.2 2.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.2 4.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.2 1.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 5.0 GO:0046785 microtubule polymerization(GO:0046785)
0.1 1.7 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 10.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 1.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 4.2 GO:0015914 phospholipid transport(GO:0015914)
0.1 3.4 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.1 2.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 4.5 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 2.1 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 2.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 2.9 GO:0006956 complement activation(GO:0006956)
0.0 7.8 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 2.0 GO:0009308 amine metabolic process(GO:0009308)
0.0 0.1 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 1.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 2.0 GO:0044782 cilium organization(GO:0044782)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:1990909 Wnt signalosome(GO:1990909)
0.7 2.0 GO:0097541 axonemal basal plate(GO:0097541)
0.5 3.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 5.8 GO:1990246 uniplex complex(GO:1990246)
0.4 4.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 4.8 GO:0000815 ESCRT III complex(GO:0000815)
0.2 1.7 GO:0045095 keratin filament(GO:0045095)
0.1 2.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 14.4 GO:0016459 myosin complex(GO:0016459)
0.1 0.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 3.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 6.1 GO:0016607 nuclear speck(GO:0016607)
0.0 2.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 2.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.0 GO:0000786 nucleosome(GO:0000786)
0.0 3.9 GO:0000785 chromatin(GO:0000785)
0.0 1.8 GO:0030027 lamellipodium(GO:0030027)
0.0 5.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 34.3 GO:0005576 extracellular region(GO:0005576)
0.0 5.0 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
1.3 3.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.6 4.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 4.9 GO:0031720 haptoglobin binding(GO:0031720)
0.4 2.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 5.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 2.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.3 5.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.3 3.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 2.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 10.5 GO:0005178 integrin binding(GO:0005178)
0.2 1.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 5.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.9 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 2.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 3.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 1.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 14.4 GO:0003774 motor activity(GO:0003774)
0.1 0.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 2.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 6.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.8 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 2.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 4.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.1 GO:0004620 phospholipase activity(GO:0004620)
0.0 5.0 GO:0015631 tubulin binding(GO:0015631)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 2.0 GO:0046982 protein heterodimerization activity(GO:0046982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 10.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.7 REACTOME OPSINS Genes involved in Opsins
0.1 2.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 2.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.6 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 5.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.7 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2