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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for maff+mafga+mafgb

Z-value: 0.90

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Transcription factors associated with maff+mafga+mafgb

Gene Symbol Gene ID Gene Info
ENSDARG00000018109 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga
ENSDARG00000028957 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ENSDARG00000100097 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
ENSDARG00000111050 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafgadr11_v1_chr3_-_55404985_554049850.502.5e-07Click!
mafgbdr11_v1_chr11_+_45300669_453006690.454.5e-06Click!
maffdr11_v1_chr12_-_19346678_19346678-0.132.0e-01Click!

Activity profile of maff+mafga+mafgb motif

Sorted Z-values of maff+mafga+mafgb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_32526799 16.88 ENSDART00000185755
si:ch73-367p23.2
chr2_-_36040820 7.67 ENSDART00000003550
nicotinamide nucleotide adenylyltransferase 2
chr6_-_35446110 7.63 ENSDART00000058773
regulator of G protein signaling 16
chr19_-_19339285 7.44 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr6_+_27667359 7.30 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr14_-_30490763 6.68 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
mitochondrial calcium uptake family, member 3b
chr3_+_15907297 6.19 ENSDART00000139206
mitogen-activated protein kinase 8 interacting protein 3
chr20_+_27393668 6.08 ENSDART00000005473
transmembrane protein 179
chr7_+_25059845 6.01 ENSDART00000077215
protein phosphatase 2, regulatory subunit B', beta
chr9_+_27411502 5.95 ENSDART00000143994
si:dkey-193n17.9
chr15_-_44512461 5.72 ENSDART00000155456
glutamate receptor, ionotropic, AMPA 4a
chr16_+_10777116 5.64 ENSDART00000190902
ATPase Na+/K+ transporting subunit alpha 3b
chr16_-_29452039 5.62 ENSDART00000148960
si:ch211-113g11.6
chr12_-_10300101 5.37 ENSDART00000126428
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr20_+_20637866 5.25 ENSDART00000060203
ENSDART00000079079
reticulon 1b
chr3_+_15907458 5.19 ENSDART00000163525
mitogen-activated protein kinase 8 interacting protein 3
chr16_-_12173554 5.07 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr6_-_31348999 5.02 ENSDART00000153734
DnaJ (Hsp40) homolog, subfamily C, member 6
chr2_+_20332044 5.00 ENSDART00000112131
phospholipid phosphatase related 4a
chr19_+_25649626 4.98 ENSDART00000146947
tachykinin 1
chr23_-_27345425 4.95 ENSDART00000022042
ENSDART00000191870
sodium channel, voltage gated, type VIII, alpha subunit a
chr21_-_43606502 4.67 ENSDART00000151030
si:ch73-362m14.4
chr3_+_31933893 4.65 ENSDART00000146509
ENSDART00000139644
lin-7 homolog B (C. elegans)
chr23_-_4915118 4.61 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr10_-_27049170 4.56 ENSDART00000143451
cornichon family AMPA receptor auxiliary protein 2
chr3_-_39171968 4.55 ENSDART00000154494
si:dkeyp-57f11.2
chr10_+_29698467 4.25 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr21_-_45613564 4.13 ENSDART00000160324

chr21_+_9666347 4.13 ENSDART00000163853
mitogen-activated protein kinase 10
chr14_-_2355833 4.11 ENSDART00000157677
si:ch73-233f7.6
chr5_+_23118470 4.01 ENSDART00000149893
neurite extension and migration factor a
chr20_+_20638034 3.99 ENSDART00000189759
reticulon 1b
chr2_-_24996441 3.98 ENSDART00000144795
solute carrier family 35, member G2a
chr8_+_14792830 3.96 ENSDART00000139972
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr8_+_53452681 3.96 ENSDART00000166705
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr13_+_28675686 3.95 ENSDART00000027213
internexin neuronal intermediate filament protein, alpha a
chr7_+_67486807 3.93 ENSDART00000159989
copine VII
chr6_+_34512313 3.89 ENSDART00000102554
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr7_-_24491614 3.87 ENSDART00000131063
si:dkeyp-75h12.5
chr19_-_9867001 3.83 ENSDART00000091695
calcium channel, voltage-dependent, gamma subunit 7a
chr21_+_18353703 3.80 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr13_+_24280380 3.77 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr7_-_57933736 3.72 ENSDART00000142580
ankyrin 2b, neuronal
chr8_+_39607466 3.71 ENSDART00000097427
musashi RNA-binding protein 1
chr17_+_27134806 3.67 ENSDART00000151901
ribosomal protein S6 kinase a, polypeptide 1
chr5_+_65491390 3.67 ENSDART00000159921
si:dkey-21e5.1
chr21_+_10794914 3.63 ENSDART00000084035
zinc finger protein 532
chr7_-_18730474 3.58 ENSDART00000170374
si:dkey-38l22.2
chr21_-_24632778 3.57 ENSDART00000132533
ENSDART00000058370
Rho GTPase activating protein 32b
chr3_-_32320537 3.53 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
chr7_+_23515966 3.49 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr6_-_10780698 3.44 ENSDART00000151714
G protein-coupled receptor 155b
chr2_+_23222939 3.43 ENSDART00000026800
kinesin-associated protein 3b
chr2_+_20331445 3.43 ENSDART00000186880
phospholipid phosphatase related 4a
chr13_-_36545258 3.40 ENSDART00000186171

chr18_+_7286788 3.36 ENSDART00000022998
si:ch73-86n2.1
chr7_-_69983948 3.30 ENSDART00000185827
potassium voltage-gated channel interacting protein 4
chr6_+_52064304 3.30 ENSDART00000153468
actin binding Rho activating protein a
chr13_+_51579851 3.29 ENSDART00000163847
NK6 homeobox 2
chr24_-_32408404 3.27 ENSDART00000144157
si:ch211-56a11.2
chr23_+_216012 3.26 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
si:ch73-162j3.4
chr9_-_4506819 3.25 ENSDART00000113975
potassium inwardly-rectifying channel, subfamily J, member 3a
chr24_+_32472155 3.23 ENSDART00000098859
neuronal differentiation 6a
chr17_+_12698532 3.20 ENSDART00000064509
ENSDART00000136830
stathmin-like 4, like
chr23_-_29502287 3.18 ENSDART00000141075
ENSDART00000053807
kinesin family member 1B
chr1_-_10048514 3.17 ENSDART00000125358
ENSDART00000054835
ring finger protein 175
chr17_-_22062364 3.17 ENSDART00000114470
tau tubulin kinase 1b
chr20_-_51917771 3.15 ENSDART00000147240
dual specificity phosphatase 10
chr21_+_20901505 3.13 ENSDART00000132741
complement component 7b
chr21_-_28340977 3.06 ENSDART00000141629
neurexin 2a
chr5_+_27137473 3.05 ENSDART00000181833
unc-5 netrin receptor Db
chr2_+_36862473 3.03 ENSDART00000135624
si:dkey-193b15.8
chr10_-_27009413 2.90 ENSDART00000139942
ENSDART00000146983
ENSDART00000132352
ubiquinol-cytochrome c reductase complex assembly factor 3
chr22_+_3238474 2.88 ENSDART00000157954
si:ch1073-178p5.3
chr21_+_30194904 2.86 ENSDART00000137023
ENSDART00000078403
si:ch211-59d17.3
chr19_-_13286722 2.84 ENSDART00000168296
ENSDART00000158330
zinc finger protein, FOG family member 2b
chr14_+_25464681 2.84 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr11_-_18791834 2.82 ENSDART00000156431
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr9_-_18424844 2.77 ENSDART00000154351
ecto-NOX disulfide-thiol exchanger 1
chr9_-_42861080 2.76 ENSDART00000193688
titin, tandem duplicate 1
chr5_-_32158198 2.72 ENSDART00000187215
ENSDART00000137503
IL-6 subfamily cytokine M17
chr11_+_30729745 2.72 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr3_-_60142530 2.64 ENSDART00000153247
si:ch211-120g10.1
chr5_-_21422390 2.63 ENSDART00000144198
teneurin transmembrane protein 1
chr20_+_46206998 2.59 ENSDART00000074482
trace amine associated receptor 15
chr3_-_32169754 2.58 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr10_+_42733210 2.58 ENSDART00000189832

chr7_+_42206543 2.57 ENSDART00000112543
phosphorylase kinase, beta
chr2_-_32356539 2.56 ENSDART00000169316
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr20_-_27864964 2.54 ENSDART00000153311
synapse differentiation inducing 1-like
chr10_+_21758811 2.53 ENSDART00000188827
protocadherin 1 gamma 11
chr25_+_20077225 2.53 ENSDART00000136543
troponin I4b, tandem duplicate 1
chr8_+_50983551 2.52 ENSDART00000142061
si:dkey-32e23.4
chr18_+_28106139 2.51 ENSDART00000089615
KIAA1549-like b
chr8_+_554531 2.45 ENSDART00000193623

chr6_-_51101834 2.45 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr11_+_25112269 2.44 ENSDART00000147546
ndrg family member 3a
chr10_+_1638876 2.42 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
small G protein signaling modulator 1b
chr3_+_29600917 2.38 ENSDART00000048867
somatostatin receptor 3
chr11_-_41130239 2.38 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr12_-_7607114 2.37 ENSDART00000158095
solute carrier family 16, member 9b
chr13_+_36146415 2.37 ENSDART00000140301
si:ch211-259k16.3
chr3_+_33300522 2.37 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr17_-_43552894 2.36 ENSDART00000181226
ENSDART00000188125
5'-nucleotidase, cytosolic IAb
chr21_+_9576176 2.36 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mitogen-activated protein kinase 10
chr3_+_30500968 2.35 ENSDART00000103447
si:dkey-13n23.3
chr2_+_55916911 2.29 ENSDART00000189483
ENSDART00000183647
ENSDART00000083470
ataxia, cerebellar, Cayman type b
chr1_+_6817292 2.29 ENSDART00000145822
ENSDART00000092118
erb-b2 receptor tyrosine kinase 4a
chr16_+_12240605 2.29 ENSDART00000060056
triosephosphate isomerase 1b
chr4_-_13156971 2.28 ENSDART00000182164
glutamate receptor interacting protein 1
chr20_-_45040916 2.27 ENSDART00000190001
kelch-like family member 29
chr7_-_19600181 2.24 ENSDART00000100757
oxidase (cytochrome c) assembly 1-like
chr8_+_52491436 2.18 ENSDART00000164298
si:ch1073-392o20.1
chr14_+_34547554 2.16 ENSDART00000074819
gamma-aminobutyric acid (GABA) A receptor, pi
chr18_-_41232297 2.14 ENSDART00000036928
F-box protein 36a
chr4_-_41269844 2.13 ENSDART00000186177

chr6_-_12135741 2.13 ENSDART00000155090
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr13_+_40034176 2.09 ENSDART00000189797
golgin A7 family, member Bb
chr11_+_6882362 2.08 ENSDART00000144181
kelch-like family member 26
chr2_+_22363824 2.07 ENSDART00000163172
heparan sulfate 2-O-sulfotransferase 1a
chr18_+_16192083 2.07 ENSDART00000133042
leucine-rich repeats and IQ motif containing 1
chr14_-_48348973 2.06 ENSDART00000185822

chr12_+_47280839 2.03 ENSDART00000187574
ryanodine receptor 2
chr8_+_53423408 2.02 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr20_+_27331008 2.02 ENSDART00000141486
protein phosphatase 4, regulatory subunit 4
chr3_+_32403758 2.02 ENSDART00000156982
si:ch211-195b15.8
chr19_-_1961024 2.02 ENSDART00000108784
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_+_52518176 1.99 ENSDART00000003278
tachykinin receptor 3-like
chr9_-_30346279 1.97 ENSDART00000089488
synaptotagmin-like 5
chr23_+_2760573 1.97 ENSDART00000129719
DNA topoisomerase I
chr7_+_50766094 1.96 ENSDART00000165037
si:ch73-380l10.2
chr14_+_18785727 1.95 ENSDART00000184452
si:ch211-111e20.1
chr15_-_26887028 1.94 ENSDART00000156292
si:dkey-243i1.1
chr19_+_43563179 1.90 ENSDART00000151478
CD164 sialomucin-like 2
chr18_-_8579907 1.85 ENSDART00000147284
si:ch211-220f12.1
chr7_-_72423666 1.84 ENSDART00000191214
rabphilin 3A homolog (mouse), b
chr17_-_45009782 1.79 ENSDART00000123971
family with sequence similarity 161, member B
chr18_-_12295092 1.78 ENSDART00000033248
family with sequence similarity 107, member B
chr12_+_48216662 1.75 ENSDART00000187369
leucine rich repeat containing 20
chr2_-_24369087 1.75 ENSDART00000081237
plasmalemma vesicle associated protein a
chr9_-_7652792 1.75 ENSDART00000137957
DnaJ (Hsp40) homolog, subfamily B, member 2
chr10_-_20175118 1.74 ENSDART00000014417
5-hydroxytryptamine (serotonin) receptor 7b
chr20_-_31075972 1.73 ENSDART00000122927
si:ch211-198b3.4
chr3_+_13929860 1.71 ENSDART00000164179
synaptonemal complex central element protein 2
chr4_-_64871624 1.70 ENSDART00000124817
zinc finger protein 988
chr24_-_25184553 1.69 ENSDART00000166917
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr22_+_10201826 1.69 ENSDART00000006513
ENSDART00000132641
pyruvate dehydrogenase E1 beta subunit
chr9_-_21230999 1.69 ENSDART00000150160
ENSDART00000102147
phospholipase A1 member A
chr9_-_43071519 1.68 ENSDART00000109099
titin, tandem duplicate 2
chr9_-_25255490 1.67 ENSDART00000141502
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a
chr7_+_26709251 1.67 ENSDART00000149426
ENSDART00000010323
CD82 molecule a
chr21_+_30084823 1.66 ENSDART00000154573
proline-rich basic protein 1
chr17_-_24564674 1.63 ENSDART00000105435
ENSDART00000135086
ATP-binding cassette, sub-family H, member 1
chr16_-_21047872 1.63 ENSDART00000131582
chromobox homolog 3b
chr3_+_25508247 1.61 ENSDART00000039448
melanin-concentrating hormone receptor 1b
chr5_+_53482597 1.60 ENSDART00000180333

chr24_-_34034931 1.57 ENSDART00000169227
acid-sensing (proton-gated) ion channel 1c
chr17_+_20204122 1.55 ENSDART00000078672
gonadotropin-releasing hormone 3
chr6_-_33685325 1.54 ENSDART00000181883
microtubule associated serine/threonine kinase 2
chr23_+_37185247 1.52 ENSDART00000146269
von Willebrand factor A domain containing 5B1
chr14_+_1687357 1.52 ENSDART00000174675
histamine receptor H2a
chr16_-_28727763 1.47 ENSDART00000149575
DC-STAMP domain containing 1
chr1_+_34203817 1.47 ENSDART00000191432
ENSDART00000046094
ADP-ribosylation factor-like 6
chr10_-_41664427 1.47 ENSDART00000150213
gamma-glutamyltransferase 1b
chr20_+_48754045 1.46 ENSDART00000062578
zgc:110348
chr12_-_3077395 1.46 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr23_-_28347039 1.45 ENSDART00000145072
neuronal differentiation 4
chr6_+_27339962 1.45 ENSDART00000193726
kelch-like family member 30
chr17_+_37932706 1.43 ENSDART00000075941
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr5_-_35888499 1.43 ENSDART00000193932
relaxin/insulin-like family peptide receptor 2, like
chr13_+_10023256 1.42 ENSDART00000110035
S1 RNA binding domain 1
chr5_-_24642026 1.42 ENSDART00000139522
si:ch211-106a19.1
chr21_+_10773522 1.39 ENSDART00000143257
zinc finger protein 532
chr4_-_39111612 1.39 ENSDART00000150394
si:dkey-122c11.8
chr14_+_31721171 1.38 ENSDART00000173034
adhesion G protein-coupled receptor G4a
chr22_-_32392252 1.37 ENSDART00000148681
ENSDART00000137945
poly(rC) binding protein 4
chr8_+_21406769 1.34 ENSDART00000135766
si:dkey-163f12.6
chr7_+_34290051 1.33 ENSDART00000123498
fin bud initiation factor b
chr3_+_30501135 1.33 ENSDART00000165869
si:dkey-13n23.3
chr2_+_12255568 1.32 ENSDART00000184164
ENSDART00000013454
phosphoribosyl transferase domain containing 1
chr23_+_19675780 1.32 ENSDART00000124335
small integral membrane protein 4
chr7_-_35516251 1.32 ENSDART00000045628
iroquois homeobox 6a
chr7_+_13609457 1.31 ENSDART00000172857
ankyrin repeat and death domain containing 1A
chr22_+_19478140 1.31 ENSDART00000135291
ENSDART00000136576
si:dkey-78l4.8
chr20_+_46183505 1.30 ENSDART00000060799
trace amine associated receptor 13b
chr7_-_11020900 1.29 ENSDART00000182976

chr6_-_36182115 1.28 ENSDART00000154639
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 2
chr5_+_53824959 1.28 ENSDART00000169565
spermidine/spermine N1-acetyltransferase family member 2b
chr10_+_17592273 1.27 ENSDART00000141221
si:dkey-76p7.5
chr19_+_8985230 1.27 ENSDART00000018973
secretory carrier membrane protein 3
chr4_+_22343093 1.26 ENSDART00000023588
guanylate cyclase activator 1A
chr5_-_9073433 1.26 ENSDART00000099891
ATP synthase membrane subunit eb
chr10_-_40448736 1.25 ENSDART00000137644
ENSDART00000168190
trace amine associated receptor 20p
chr14_+_4276394 1.23 ENSDART00000038301
glucosamine-6-phosphate deaminase 2
chr10_-_19006579 1.22 ENSDART00000141764
adrenoceptor alpha 1Ab
chr22_+_2254972 1.21 ENSDART00000144906
zinc finger protein 1157
chr19_-_17385548 1.21 ENSDART00000162383
NFKB inhibitor interacting Ras-like 1
chr2_+_10642047 1.20 ENSDART00000091570
family with sequence similarity 69, member Aa
chr3_-_33029426 1.19 ENSDART00000181287

chr16_+_43077909 1.19 ENSDART00000014140
RUN domain containing 3b

Network of associatons between targets according to the STRING database.

First level regulatory network of maff+mafga+mafgb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 11.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
1.2 5.0 GO:0007638 mechanosensory behavior(GO:0007638)
1.1 3.2 GO:0048917 posterior lateral line ganglion development(GO:0048917) neuron projection maintenance(GO:1990535)
1.0 4.0 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
1.0 5.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.0 5.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.9 4.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.7 7.4 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.7 3.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.6 3.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.6 2.3 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.6 5.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.6 2.2 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.6 2.8 GO:0007624 ultradian rhythm(GO:0007624)
0.5 7.7 GO:0009435 NAD biosynthetic process(GO:0009435)
0.5 8.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.5 2.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.5 2.9 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.4 1.2 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.4 2.0 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.4 6.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.4 2.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 3.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 1.5 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.3 0.9 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.3 6.0 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.3 6.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 2.0 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.3 1.7 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.3 4.4 GO:0048769 sarcomerogenesis(GO:0048769)
0.3 1.4 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.3 1.6 GO:0071467 cellular response to pH(GO:0071467)
0.2 8.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 0.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 8.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 0.9 GO:1901317 regulation of sperm motility(GO:1901317)
0.2 0.9 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.2 0.9 GO:0061549 sympathetic ganglion development(GO:0061549)
0.2 2.3 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 1.5 GO:0001839 neural plate morphogenesis(GO:0001839)
0.2 3.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.2 0.8 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) dGDP metabolic process(GO:0046066)
0.2 2.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 2.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 3.5 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.2 1.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 2.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 2.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 2.3 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.2 1.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.2 2.4 GO:0042407 cristae formation(GO:0042407)
0.2 3.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 0.7 GO:0033605 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.2 1.2 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.2 0.8 GO:0045822 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.2 1.2 GO:0031179 peptide modification(GO:0031179)
0.1 0.6 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 7.1 GO:0021591 ventricular system development(GO:0021591)
0.1 13.3 GO:0070509 calcium ion import(GO:0070509)
0.1 0.9 GO:0002931 response to ischemia(GO:0002931)
0.1 1.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.5 GO:0070285 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) pigment cell development(GO:0070285)
0.1 2.0 GO:0006265 DNA topological change(GO:0006265)
0.1 1.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 6.5 GO:0048484 enteric nervous system development(GO:0048484)
0.1 1.4 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 3.1 GO:0019835 cytolysis(GO:0019835)
0.1 1.7 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 4.7 GO:0051057 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 5.6 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 0.3 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.1 0.6 GO:0032218 riboflavin transport(GO:0032218)
0.1 1.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 2.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.0 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.6 GO:0044211 CTP salvage(GO:0044211)
0.1 2.7 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.1 4.6 GO:0030641 regulation of cellular pH(GO:0030641)
0.1 0.4 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 0.9 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 3.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.6 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 3.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 2.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 2.1 GO:0042310 vasoconstriction(GO:0042310)
0.1 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.9 GO:0007099 centriole replication(GO:0007099)
0.1 1.4 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 4.1 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 3.8 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 4.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 3.2 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 1.2 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.5 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.5 GO:0030431 sleep(GO:0030431)
0.0 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 1.3 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.7 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 6.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.7 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031) cellular response to leucine starvation(GO:1990253)
0.0 0.4 GO:0001966 thigmotaxis(GO:0001966) myotome development(GO:0061055)
0.0 0.6 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.9 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 3.8 GO:0044782 cilium organization(GO:0044782)
0.0 0.5 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.9 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 1.3 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 0.4 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.3 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 2.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 1.1 GO:0022900 electron transport chain(GO:0022900)
0.0 0.6 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:0039022 pronephric duct development(GO:0039022) nephric duct development(GO:0072176)
0.0 0.9 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.4 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.7 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.4 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.3 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 2.2 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 2.8 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.8 4.0 GO:0005883 neurofilament(GO:0005883)
0.8 4.6 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.5 1.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.5 6.7 GO:1990246 uniplex complex(GO:1990246)
0.5 8.2 GO:0031209 SCAR complex(GO:0031209)
0.4 2.6 GO:0001650 fibrillar center(GO:0001650)
0.3 4.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.3 2.9 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3 1.7 GO:0000801 central element(GO:0000801)
0.3 1.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 2.0 GO:0097225 sperm midpiece(GO:0097225)
0.2 3.8 GO:0005869 dynactin complex(GO:0005869)
0.2 3.7 GO:0030315 T-tubule(GO:0030315)
0.2 9.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 2.4 GO:0061617 MICOS complex(GO:0061617)
0.2 5.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 10.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 3.1 GO:0005579 membrane attack complex(GO:0005579)
0.2 6.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.1 GO:0072487 MSL complex(GO:0072487)
0.1 4.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 5.1 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 3.9 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.5 GO:0060170 ciliary membrane(GO:0060170)
0.1 2.8 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 2.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 2.2 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.7 GO:0043204 perikaryon(GO:0043204)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.9 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.2 GO:0070461 SAGA-type complex(GO:0070461)
0.0 2.6 GO:0014069 postsynaptic density(GO:0014069)
0.0 8.3 GO:0030424 axon(GO:0030424)
0.0 5.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 12.4 GO:0030425 dendrite(GO:0030425)
0.0 9.0 GO:0043005 neuron projection(GO:0043005)
0.0 1.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 2.7 GO:0030017 sarcomere(GO:0030017)
0.0 2.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 18.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.6 GO:0005929 cilium(GO:0005929)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.4 GO:0008432 JUN kinase binding(GO:0008432)
1.7 5.0 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
1.2 4.6 GO:0097016 L27 domain binding(GO:0097016)
1.0 3.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
1.0 2.9 GO:1901612 cardiolipin binding(GO:1901612)
0.9 8.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.6 6.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 2.3 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.5 1.6 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.5 1.5 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.4 7.7 GO:0070566 adenylyltransferase activity(GO:0070566)
0.4 1.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.4 5.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.4 5.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 1.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 3.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 3.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 1.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 1.7 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.3 8.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 6.0 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.3 1.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 3.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 0.9 GO:0031701 angiotensin receptor binding(GO:0031701)
0.3 2.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 2.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 1.0 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.2 2.2 GO:0032977 membrane insertase activity(GO:0032977)
0.2 6.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 2.2 GO:0005042 netrin receptor activity(GO:0005042)
0.2 2.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 2.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 5.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 1.6 GO:0019808 polyamine binding(GO:0019808)
0.2 2.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 3.7 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 3.2 GO:0019894 kinesin binding(GO:0019894)
0.2 1.0 GO:0019202 amino acid kinase activity(GO:0019202)
0.2 7.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 1.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 1.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 2.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 2.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 2.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 5.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 3.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.6 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 5.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 5.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.7 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 2.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.6 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.9 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.6 GO:0005113 patched binding(GO:0005113)
0.1 2.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 6.6 GO:0030276 clathrin binding(GO:0030276)
0.1 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 3.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0099589 serotonin-gated cation channel activity(GO:0022850) serotonin receptor activity(GO:0099589)
0.0 0.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 2.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 2.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 1.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:2001069 glycogen binding(GO:2001069)
0.0 2.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.8 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 1.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.9 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.8 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.4 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 2.9 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.8 GO:0051427 hormone receptor binding(GO:0051427)
0.0 2.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 7.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.4 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 13.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0035255 GKAP/Homer scaffold activity(GO:0030160) ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.3 GO:0000287 magnesium ion binding(GO:0000287)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 17.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 3.9 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 3.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 1.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 3.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.6 6.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 4.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 3.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 1.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 7.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 2.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation