Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for meis1a+meis1b

Z-value: 0.93

Motif logo

Transcription factors associated with meis1a+meis1b

Gene Symbol Gene ID Gene Info
ENSDARG00000002937 Meis homeobox 1 a
ENSDARG00000012078 Meis homeobox 1 b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meis1bdr11_v1_chr13_-_5569562_5569562-0.187.7e-02Click!
meis1adr11_v1_chr1_+_51475094_51475094-0.065.6e-01Click!

Activity profile of meis1a+meis1b motif

Sorted Z-values of meis1a+meis1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_52512025 12.58 ENSDART00000056095
fatty acid binding protein 10a, liver basic
chr20_-_5291012 8.81 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr19_+_7567763 7.17 ENSDART00000140411
S100 calcium binding protein A11
chr14_-_30390145 6.89 ENSDART00000045423
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr12_-_4249000 6.74 ENSDART00000059298
zgc:92313
chr20_-_48701593 6.64 ENSDART00000132835
paired box 1b
chr8_-_13972626 6.58 ENSDART00000144296
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr17_+_33375469 5.81 ENSDART00000032827
zgc:162964
chr6_-_39199070 5.65 ENSDART00000131793
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr25_-_17403598 5.40 ENSDART00000104216
cytochrome P450, family 2, subfamily X, polypeptide 9
chr25_-_22191983 4.80 ENSDART00000191181
plakophilin 3a
chr25_+_10410620 4.66 ENSDART00000151886
ets homologous factor
chr9_+_7358749 4.46 ENSDART00000081660
Indian hedgehog homolog a
chr16_+_26612401 4.35 ENSDART00000145571
erythrocyte membrane protein band 4.1 like 4B
chr21_-_22435957 4.27 ENSDART00000137959
interleukin 7 receptor
chr16_+_11558868 4.18 ENSDART00000112497
ENSDART00000180445
zgc:198329
chr18_+_18863167 4.12 ENSDART00000091094
plasmolipin
chr20_-_7176809 4.07 ENSDART00000012247
ENSDART00000125019
24-dehydrocholesterol reductase
chr10_-_26512742 3.93 ENSDART00000135951
si:dkey-5g14.1
chr10_-_3295197 3.90 ENSDART00000109131
slc25a1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1b
chr13_-_34858500 3.84 ENSDART00000184843
serine palmitoyltransferase, long chain base subunit 3
chr20_-_8094718 3.70 ENSDART00000122902
si:ch211-232i5.3
chr19_+_7636941 3.59 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr22_-_5682494 3.53 ENSDART00000012686
deoxyribonuclease 1 like 4, tandem duplicate 1
chr2_-_55298075 3.50 ENSDART00000186404
ENSDART00000149062
RAB8A, member RAS oncogene family
chr1_-_9652547 3.45 ENSDART00000016750
ENSDART00000127735
ENSDART00000160474
ENSDART00000080323
ENSDART00000126996
ENSDART00000126877
ENSDART00000123773
UDP glucuronosyltransferase 5 family, polypeptide B3
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
UDP glucuronosyltransferase 5 family, polypeptide B1
chr5_+_26805608 3.44 ENSDART00000111019
RAB, member RAS oncogene family-like 6b
chr6_+_23057311 3.41 ENSDART00000026448
envoplakin a
chr6_-_43387920 3.29 ENSDART00000154434
FERM domain containing 4Ba
chr20_-_5267600 3.18 ENSDART00000099258
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4
chr17_+_39741926 3.15 ENSDART00000154996
ENSDART00000154599
si:dkey-229e3.2
chr5_+_30741730 3.12 ENSDART00000098246
ENSDART00000186992
ENSDART00000182533
finTRIM family, member 83
chr22_-_24791505 3.12 ENSDART00000136837
vitellogenin 4
chr7_+_6990510 3.10 ENSDART00000138948
copper chaperone for superoxide dismutase
chr24_-_17047918 3.08 ENSDART00000020204
methionine sulfoxide reductase B2
chr25_-_22191733 3.07 ENSDART00000067478
plakophilin 3a
chr1_-_20593778 3.05 ENSDART00000124770
UDP glycosyltransferase 8
chr25_+_10830269 3.05 ENSDART00000175736
si:ch211-147g22.5
chr4_-_9549693 3.02 ENSDART00000160242

chr22_+_15336752 2.91 ENSDART00000139070
sulfotransferase family 3, cytosolic sulfotransferase 2
chr13_-_337318 2.90 ENSDART00000166175
zgc:171534
chr22_+_5682635 2.86 ENSDART00000140680
ENSDART00000131308
deoxyribonuclease 1 like 4, tandem duplicate 2
chr9_+_23770666 2.84 ENSDART00000182493
si:ch211-219a4.3
chr13_-_21701323 2.82 ENSDART00000164112
si:dkey-191g9.7
chr3_+_26734162 2.73 ENSDART00000114552
si:dkey-202l16.5
chr17_+_47174525 2.72 ENSDART00000156831
si:dkeyp-47f9.4
chr6_+_49926115 2.66 ENSDART00000018523
adenosylhomocysteinase
chr12_-_4220713 2.65 ENSDART00000129427
vitamin K epoxide reductase complex, subunit 1
chr15_+_9294620 2.59 ENSDART00000133588
ENSDART00000140009
solute carrier family 37 (glucose-6-phosphate transporter), member 4a
chr10_-_26512993 2.56 ENSDART00000188549
ENSDART00000193316
si:dkey-5g14.1
chr10_+_29770120 2.56 ENSDART00000100032
ENSDART00000193205
hypoxia up-regulated 1
chr11_-_16975190 2.54 ENSDART00000122222
succinate-CoA ligase, GDP-forming, beta subunit
chr11_+_24729346 2.52 ENSDART00000087740
zgc:153953
chr17_+_12138715 2.50 ENSDART00000112888
zgc:174379
chr9_+_38168012 2.42 ENSDART00000102445
cytoplasmic linker associated protein 1a
chr15_-_29598679 2.41 ENSDART00000155153
si:ch211-207n23.2
chr2_-_22993601 2.40 ENSDART00000125049
ENSDART00000099735
MLLT1, super elongation complex subunit b
chr17_-_43594864 2.39 ENSDART00000139980
zinc finger, FYVE domain containing 28
chr7_-_23848012 2.37 ENSDART00000146104
ENSDART00000175108
si:ch211-200p22.4
chr13_-_8692860 2.36 ENSDART00000058107
multiple coagulation factor deficiency 2
chr4_-_7876005 2.34 ENSDART00000109252
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr13_+_24584401 2.32 ENSDART00000057599
fucose mutarotase
chr16_-_13613475 2.30 ENSDART00000139102
D site albumin promoter binding protein b
chr17_-_15667198 2.30 ENSDART00000142972
ENSDART00000132571
ENSDART00000189936
mannosidase, endo-alpha
chr5_+_45007962 2.30 ENSDART00000010786
doublesex and mab-3 related transcription factor 2a
chr6_+_39493864 2.28 ENSDART00000086263
methyltransferase like 7A
chr10_-_25328814 2.27 ENSDART00000123820
transmembrane protein 135
chr13_+_35765317 2.27 ENSDART00000100156
ENSDART00000167650
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr6_+_3280939 2.25 ENSDART00000151359
lysine (K)-specific demethylase 4A, genome duplicate a
chr10_-_22831611 2.24 ENSDART00000160115
period circadian clock 1a
chr10_+_26973063 2.21 ENSDART00000143162
ENSDART00000186210
transmembrane 7 superfamily member 2
chr6_-_8580857 2.20 ENSDART00000138858
ENSDART00000041142
myosin, heavy chain 11a, smooth muscle
chr7_+_21768452 2.19 ENSDART00000127719
lysine (K)-specific demethylase 6B, a
chr8_-_41519234 2.19 ENSDART00000167283
ENSDART00000180666
golgin A1
chr11_-_42230491 2.11 ENSDART00000164423

chr5_+_31480342 2.08 ENSDART00000098197
si:dkey-220k22.1
chr12_+_46543572 2.06 ENSDART00000167510
HID1 domain containing b
chr18_+_20047374 2.03 ENSDART00000146957
uveal autoantigen with coiled-coil domains and ankyrin repeats a
chr4_-_7875808 2.01 ENSDART00000162276
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr17_-_21842135 2.00 ENSDART00000154927
CUB and zona pellucida-like domains 1, tandem duplicate 2
chr4_-_21466825 1.97 ENSDART00000066897
PRKC, apoptosis, WT1, regulator
chr2_-_41861040 1.95 ENSDART00000045763
kelch-like ECH-associated protein 1a
chr10_+_25726694 1.95 ENSDART00000140308
UDP glucuronosyltransferase 5 family, polypeptide D1
chr24_-_13272842 1.94 ENSDART00000146790
ENSDART00000066703
retinol dehydrogenase 10a
chr7_-_41013575 1.93 ENSDART00000150139
insulin induced gene 1
chr5_+_35744623 1.92 ENSDART00000148213
ENSDART00000076627
Yip1 domain family, member 6
chr8_-_41519064 1.90 ENSDART00000098578
ENSDART00000112214
golgin A1
chr13_-_8692432 1.90 ENSDART00000058106
multiple coagulation factor deficiency 2
chr8_+_14959587 1.90 ENSDART00000138548
ENSDART00000041697
c-abl oncogene 2, non-receptor tyrosine kinase
chr16_-_13612650 1.89 ENSDART00000080372
D site albumin promoter binding protein b
chr10_-_45210184 1.89 ENSDART00000167128
poly (ADP-ribose) glycohydrolase, like
chr13_-_48161568 1.89 ENSDART00000109469
ENSDART00000188052
ENSDART00000193446
ENSDART00000189509
ENSDART00000184810
golgin A4
chr8_+_53051701 1.86 ENSDART00000131514
NAD kinase a
chr4_-_14191717 1.82 ENSDART00000147928
pseudouridylate synthase 7-like
chr1_+_58922027 1.80 ENSDART00000159479
thyroid hormone receptor interactor 10b
chr2_-_28671139 1.79 ENSDART00000165272
ENSDART00000164657
7-dehydrocholesterol reductase
chr8_-_31384607 1.77 ENSDART00000164134
ENSDART00000024872
cAMP responsive element binding protein 3-like 3 like
chr6_+_34870374 1.77 ENSDART00000149356
interleukin 23 receptor
chr5_+_21922534 1.76 ENSDART00000148092
si:ch73-92i20.1
chr13_+_15182149 1.75 ENSDART00000193644
ENSDART00000134421
ENSDART00000086281
mitochondrial antiviral signaling protein
chr3_-_55478647 1.75 ENSDART00000153774
endoplasmic reticulum to nucleus signaling 1
chr20_-_35554451 1.74 ENSDART00000189085
adhesion G protein-coupled receptor F7
chr7_-_19369002 1.74 ENSDART00000165680
netrin 4
chr5_+_24245682 1.72 ENSDART00000049003
ATPase H+ transporting V1 subunit Aa
chr20_-_26929685 1.72 ENSDART00000132556
finTRIM family, member 79
chr8_+_19621511 1.71 ENSDART00000017128
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr7_-_19526721 1.69 ENSDART00000114203
mannosidase, alpha, class 2B, member 2
chr4_-_14191434 1.65 ENSDART00000142374
ENSDART00000136730
pseudouridylate synthase 7-like
chr7_-_69184420 1.65 ENSDART00000168311
ENSDART00000159239
ENSDART00000161319
ubiquitin specific peptidase 10
chr7_+_55292959 1.64 ENSDART00000147539
ENSDART00000073555
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr22_+_39084829 1.64 ENSDART00000002826
GDP-mannose pyrophosphorylase B
chr12_+_33320884 1.63 ENSDART00000188988
casein kinase 1, delta b
chr2_+_11028923 1.63 ENSDART00000076725
acyl-CoA thioesterase 11a
chr15_+_14378829 1.62 ENSDART00000160145
si:ch211-11n16.2
chr20_+_26987416 1.59 ENSDART00000012816
sel-1 suppressor of lin-12-like (C. elegans)
chr24_-_26369185 1.59 ENSDART00000080039
leucine rich repeat containing 31
chr8_-_16464453 1.58 ENSDART00000098691
ring finger protein 11b
chr19_+_33850705 1.57 ENSDART00000160356
peroxisomal biogenesis factor 1
chr20_-_26467307 1.55 ENSDART00000078072
ENSDART00000158213
A kinase (PRKA) anchor protein 12b
chr10_+_10387328 1.55 ENSDART00000080904
sarcosine dehydrogenase
chr4_+_60664235 1.54 ENSDART00000186182

chr22_-_22231720 1.53 ENSDART00000160165
adaptor-related protein complex 3, delta 1 subunit
chr4_-_14192254 1.53 ENSDART00000143804
pseudouridylate synthase 7-like
chr1_+_39859782 1.53 ENSDART00000149984
interferon regulatory factor 2a
chr20_+_35473288 1.50 ENSDART00000047195
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1
chr15_-_29598444 1.50 ENSDART00000154847
si:ch211-207n23.2
chr4_-_18954001 1.49 ENSDART00000144814
si:dkey-31f5.8
chr12_+_1286642 1.48 ENSDART00000157467
phosphatidylethanolamine N-methyltransferase
chr13_-_33227411 1.47 ENSDART00000057386
golgin A5
chr19_+_20778011 1.47 ENSDART00000024208
nuclear transport factor 2, like
chr19_+_19762183 1.46 ENSDART00000163611
ENSDART00000187604
homeobox A3a
chr20_-_37813863 1.45 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr23_+_21405201 1.44 ENSDART00000144409
intermediate filament family orphan 2a
chr2_-_26527730 1.43 ENSDART00000138693
si:ch211-106k21.5
chr3_+_17634952 1.43 ENSDART00000191833
RAB5C, member RAS oncogene family
chr1_-_39859626 1.42 ENSDART00000053763
dCMP deaminase
chr17_+_34186632 1.41 ENSDART00000014306
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr5_-_3991655 1.41 ENSDART00000159368
myosin XIX
chr23_-_10254288 1.40 ENSDART00000081215
keratin 8
chr5_-_36328688 1.40 ENSDART00000011399
ephrin-B1
chr12_-_3992839 1.40 ENSDART00000126100
si:ch211-136m16.8
chr19_+_19772765 1.40 ENSDART00000182028
ENSDART00000161019
homeobox A3a
chr2_-_27855576 1.39 ENSDART00000121623

chr8_+_19621731 1.39 ENSDART00000144667
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr12_-_26538823 1.38 ENSDART00000143213
acyl-CoA synthetase family member 2
chr16_+_50089417 1.37 ENSDART00000153675
nuclear receptor subfamily 1, group D, member 2a
chr11_-_40128722 1.36 ENSDART00000165781
family with sequence similarity 83, member E
chr20_-_13673566 1.36 ENSDART00000181641
si:ch211-122h15.4
chr1_-_53880639 1.36 ENSDART00000010543
LTV1 ribosome biogenesis factor
chr5_-_37341044 1.35 ENSDART00000084675
WD repeat domain 44
chr6_+_9318052 1.34 ENSDART00000162324
kalirin RhoGEF kinase b
chr14_+_29941445 1.34 ENSDART00000181761
family with sequence similarity 149 member A
chr5_+_45008418 1.31 ENSDART00000189882
doublesex and mab-3 related transcription factor 2a
chr21_+_5888641 1.30 ENSDART00000091331
proline dehydrogenase (oxidase) 1a
chr8_-_25605537 1.30 ENSDART00000005906
serine/threonine kinase 38a
chr4_-_21466480 1.29 ENSDART00000139962
PRKC, apoptosis, WT1, regulator
chr2_-_11027258 1.29 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
single stranded DNA binding protein 3a
chr18_+_507618 1.27 ENSDART00000159464
neural precursor cell expressed, developmentally down-regulated 4a
chr21_+_5960443 1.27 ENSDART00000149689
MOB kinase activator 1Bb
chr11_+_37251825 1.26 ENSDART00000169804
interleukin 17 receptor C
chr1_+_58323980 1.26 ENSDART00000145743
si:dkey-222h21.3
chr17_-_26935339 1.26 ENSDART00000139946
NIPA-like domain containing 3
chr15_+_24588963 1.21 ENSDART00000155075
zgc:198241
chr4_-_18281070 1.21 ENSDART00000135330
ENSDART00000179075
ENSDART00000046871
UHRF1 binding protein 1-like
chr9_+_33267211 1.20 ENSDART00000025635
ubiquitin specific peptidase 9
chr4_-_76205022 1.20 ENSDART00000159687
ENSDART00000187593
si:ch211-106j21.5
chr15_+_15516612 1.20 ENSDART00000016024
tnf receptor-associated factor 4a
chr4_-_15420452 1.19 ENSDART00000016230
plexin A4
chr3_-_57666996 1.18 ENSDART00000166855
TIMP metallopeptidase inhibitor 2b
chr25_+_5604512 1.17 ENSDART00000042781
plexin b2b
chr23_-_24488696 1.15 ENSDART00000155593
transmembrane protein 82
chr21_+_11749097 1.15 ENSDART00000102408
ENSDART00000102404
elongation factor, RNA polymerase II, 2
chr12_-_17593030 1.14 ENSDART00000168758
ubiquitin specific peptidase 42
chr7_+_24006875 1.14 ENSDART00000033755
homeobox and leucine zipper encoding b
chr4_+_25693463 1.13 ENSDART00000132864
acyl-CoA thioesterase 18
chr16_-_43335914 1.12 ENSDART00000111963
ATPase family, AAA domain containing 2
chr5_+_37091626 1.11 ENSDART00000161054
transgelin 2
chr5_+_37744625 1.11 ENSDART00000014031
D4, zinc and double PHD fingers family 2
chr19_-_24988640 1.10 ENSDART00000104033
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 1
chr17_-_21418340 1.10 ENSDART00000007021
ATPase, H+ transporting, lysosomal, V1 subunit B, member a
chr18_+_45862414 1.09 ENSDART00000024615
arginyl aminopeptidase like 1
chr10_-_6588793 1.09 ENSDART00000163788
chromodomain helicase DNA binding protein 1
chr3_-_60401826 1.08 ENSDART00000144030
ENSDART00000160821
si:ch211-214b16.4
chr11_+_44804685 1.07 ENSDART00000163660
striatin, calmodulin binding protein
chr16_+_40043673 1.07 ENSDART00000102552
ENSDART00000125484
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr1_-_59216197 1.05 ENSDART00000062426
lysophosphatidic acid receptor 2b
chr24_-_27400017 1.05 ENSDART00000145829
chemokine (C-C motif) ligand 34b, duplicate 1
chr19_-_34742440 1.04 ENSDART00000122625
ENSDART00000175621
elongator acetyltransferase complex subunit 2
chr2_+_19236969 1.03 ENSDART00000163875
ENSDART00000168644
coiled-coil and C2 domain containing 1B
chr16_-_17577581 1.03 ENSDART00000186475
ENSDART00000137215
caspase 2, apoptosis-related cysteine peptidase
chr6_+_58280936 1.03 ENSDART00000155244
Ral GTPase activating protein, beta subunit (non-catalytic)
chr1_+_58139102 1.01 ENSDART00000134826
si:ch211-15j1.4
chr20_-_5254610 1.01 ENSDART00000057699
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 2
chr24_+_27268001 0.99 ENSDART00000122639
vasoactive intestinal peptide receptor 2
chr22_-_18164835 0.98 ENSDART00000143189
regulatory factor X-associated ankyrin-containing protein
chr7_-_51102479 0.98 ENSDART00000174023
collagen, type IV, alpha 6
chr9_+_38043337 0.97 ENSDART00000022574
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr1_+_58194268 0.96 ENSDART00000146252
si:dkey-222h21.11
chr15_-_44275069 0.95 ENSDART00000124980

chr12_-_35582683 0.94 ENSDART00000167933
SEC24 homolog C, COPII coat complex component

Network of associatons between targets according to the STRING database.

First level regulatory network of meis1a+meis1b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:2000257 regulation of protein activation cascade(GO:2000257)
1.3 14.8 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.1 6.9 GO:1902023 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
1.0 3.9 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.9 0.9 GO:0015809 arginine transport(GO:0015809)
0.9 2.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.9 3.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.8 3.1 GO:0030091 protein repair(GO:0030091)
0.7 2.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.6 1.9 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.6 4.5 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.6 0.6 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.5 1.5 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.5 1.5 GO:1901052 sarcosine metabolic process(GO:1901052)
0.5 1.4 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.4 2.7 GO:0046498 S-adenosylmethionine cycle(GO:0033353) S-adenosylhomocysteine metabolic process(GO:0046498)
0.4 3.0 GO:0060017 parathyroid gland development(GO:0060017)
0.4 2.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4 1.2 GO:0007414 axonal defasciculation(GO:0007414)
0.4 2.3 GO:0006004 fucose metabolic process(GO:0006004)
0.4 4.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.4 3.4 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.4 6.4 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.4 1.4 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.3 1.7 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.3 1.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.3 2.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 1.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.3 3.2 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.3 0.9 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.3 1.7 GO:0006013 mannose metabolic process(GO:0006013)
0.3 1.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.3 1.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.2 0.7 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.2 0.9 GO:1903232 melanosome assembly(GO:1903232)
0.2 1.4 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.2 4.3 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.2 2.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 2.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.2 3.1 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 0.8 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.2 5.0 GO:0001522 pseudouridine synthesis(GO:0001522)
0.2 0.6 GO:1902001 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.2 1.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 1.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2 1.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 3.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.2 0.9 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.7 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.2 0.8 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 0.8 GO:0097186 amelogenesis(GO:0097186)
0.2 1.0 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 0.9 GO:0016559 peroxisome fission(GO:0016559)
0.2 1.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 4.0 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 1.9 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.1 3.1 GO:0032355 response to estradiol(GO:0032355)
0.1 0.6 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.6 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.8 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of DNA-templated transcription in response to stress(GO:0043620)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.2 GO:0042542 response to hydrogen peroxide(GO:0042542) entrainment of circadian clock by photoperiod(GO:0043153)
0.1 5.5 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 3.0 GO:0043171 peptide catabolic process(GO:0043171)
0.1 2.9 GO:0051923 sulfation(GO:0051923)
0.1 3.6 GO:0007548 sex differentiation(GO:0007548)
0.1 2.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 0.9 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 1.1 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.9 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:0045730 respiratory burst(GO:0045730)
0.1 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.5 GO:0044241 lipid digestion(GO:0044241)
0.1 2.6 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.1 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 3.8 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 6.2 GO:0033339 pectoral fin development(GO:0033339)
0.1 2.4 GO:0070142 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.1 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.1 1.6 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.1 0.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.7 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.1 1.1 GO:0010883 regulation of lipid storage(GO:0010883)
0.1 1.3 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.6 GO:0009146 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.5 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 1.5 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.1 0.8 GO:0035264 multicellular organism growth(GO:0035264)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 3.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 6.3 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 1.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.2 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 1.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.8 GO:1903010 regulation of bone development(GO:1903010)
0.1 1.7 GO:0070831 basement membrane assembly(GO:0070831)
0.1 2.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.1 0.9 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 0.7 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 2.5 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.1 6.6 GO:0007043 cell-cell junction assembly(GO:0007043)
0.1 0.3 GO:0060544 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.1 0.9 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.4 GO:0048069 eye pigmentation(GO:0048069)
0.1 2.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 1.9 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.1 0.4 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.9 GO:0060021 palate development(GO:0060021)
0.1 0.3 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 1.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 1.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 3.8 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 0.2 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.0 3.3 GO:0008202 steroid metabolic process(GO:0008202)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 1.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 2.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.9 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 1.4 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.7 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.5 GO:0021986 habenula development(GO:0021986)
0.0 2.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.6 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0045658 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.0 1.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.1 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.6 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 2.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.4 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.1 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.0 0.5 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.1 GO:0048916 posterior lateral line development(GO:0048916)
0.0 0.4 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.6 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.8 2.5 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.8 2.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.8 4.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.6 1.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.6 1.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.4 7.3 GO:0030057 desmosome(GO:0030057)
0.4 3.8 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.3 1.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 2.0 GO:0016234 inclusion body(GO:0016234)
0.2 0.9 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 2.4 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.2 0.8 GO:0033186 CAF-1 complex(GO:0033186)
0.2 0.5 GO:1990745 EARP complex(GO:1990745)
0.2 1.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 1.0 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 0.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 0.5 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 3.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 2.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.4 GO:0045095 keratin filament(GO:0045095)
0.1 1.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 2.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 2.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.7 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.6 GO:0032797 SMN complex(GO:0032797)
0.1 8.3 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 1.5 GO:0043195 terminal bouton(GO:0043195)
0.1 2.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.6 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 3.4 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.8 GO:0005903 brush border(GO:0005903)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 3.1 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 3.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 5.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 3.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 8.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.4 GO:0031082 BLOC complex(GO:0031082)
0.0 4.0 GO:0005764 lysosome(GO:0005764)
0.0 8.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 5.1 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.0 GO:0000776 kinetochore(GO:0000776)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.9 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 14.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
2.1 12.6 GO:0032052 bile acid binding(GO:0032052)
1.0 6.9 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.9 2.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.8 2.5 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.8 2.3 GO:0042806 fucose binding(GO:0042806)
0.8 3.1 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.6 6.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.6 3.4 GO:0019215 intermediate filament binding(GO:0019215)
0.5 3.8 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.5 4.5 GO:0005113 patched binding(GO:0005113)
0.5 1.9 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.5 1.4 GO:0047760 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.4 3.1 GO:0045735 nutrient reservoir activity(GO:0045735)
0.4 1.6 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.4 3.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 1.5 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.4 1.9 GO:0008142 oxysterol binding(GO:0008142)
0.3 1.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 3.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 4.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.3 7.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.3 2.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 4.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 2.4 GO:0043515 kinetochore binding(GO:0043515)
0.3 1.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 7.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.3 5.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 1.0 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.2 4.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 2.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 2.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 0.6 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2 0.8 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.2 1.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 2.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 0.5 GO:0098808 mRNA cap binding(GO:0098808)
0.2 2.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 2.7 GO:0048038 quinone binding(GO:0048038)
0.1 2.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.8 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 7.6 GO:0005507 copper ion binding(GO:0005507)
0.1 4.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.6 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 2.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 1.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 2.4 GO:0031267 small GTPase binding(GO:0031267)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.1 0.9 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 5.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 4.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.1 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.8 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 5.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 1.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 6.1 GO:0045296 cadherin binding(GO:0045296)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 6.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 1.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 1.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 4.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.7 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 1.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 4.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 7.1 GO:0003774 motor activity(GO:0003774)
0.0 6.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 2.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.1 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 2.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 2.8 GO:0042393 histone binding(GO:0042393)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 7.6 GO:0005525 GTP binding(GO:0005525)
0.0 2.8 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.8 PID IL23 PATHWAY IL23-mediated signaling events
0.1 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 0.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 1.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 1.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 1.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 6.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 4.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.4 4.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 2.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 8.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 6.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 2.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 8.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.0 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 1.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 3.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 4.0 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.1 0.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 3.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors