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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for meox2a

Z-value: 1.10

Motif logo

Transcription factors associated with meox2a

Gene Symbol Gene ID Gene Info
ENSDARG00000040911 mesenchyme homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meox2adr11_v1_chr15_-_34468599_344685990.056.5e-01Click!

Activity profile of meox2a motif

Sorted Z-values of meox2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31267268 15.91 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr5_+_32222303 11.38 ENSDART00000051362
myosin heavy chain 4
chr6_+_55032439 10.22 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
myosin binding protein Hb
chr23_-_27571667 8.31 ENSDART00000008174
phosphofructokinase, muscle a
chr23_+_26026383 7.86 ENSDART00000141553
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr15_+_45563656 6.68 ENSDART00000157501
claudin 15-like b
chr2_-_30324610 6.56 ENSDART00000185422
junctophilin 1b
chr15_+_45563491 6.12 ENSDART00000191169
claudin 15-like b
chr5_+_2815021 5.72 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr6_-_58764672 5.67 ENSDART00000154322
sterol O-acyltransferase 2
chr19_+_9295244 5.51 ENSDART00000132255
ENSDART00000144299
si:ch73-15n24.1
chr11_-_2131280 5.04 ENSDART00000008409
calcium binding and coiled-coil domain 1b
chr12_-_26407092 4.89 ENSDART00000178687
myozenin 1b
chr8_-_13972626 4.85 ENSDART00000144296
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr5_-_26118855 4.59 ENSDART00000009028
elastase 3 like
chr8_+_39724138 4.53 ENSDART00000009323
phospholipase A2, group IB (pancreas)
chr16_+_12836143 4.51 ENSDART00000067741
calcium channel, voltage-dependent, gamma subunit 6b
chr5_-_63509581 4.40 ENSDART00000097325
complement component 5
chr20_-_40755614 4.12 ENSDART00000061247
connexin 32.3
chr18_+_7286788 3.91 ENSDART00000022998
si:ch73-86n2.1
chr8_-_10932206 3.86 ENSDART00000124313
nuclear receptor subfamily 1, group H, member 5
chr11_-_1509773 3.79 ENSDART00000050762
phosphatase and actin regulator 3b
chr25_+_20077225 3.71 ENSDART00000136543
troponin I4b, tandem duplicate 1
chr24_-_29963858 3.67 ENSDART00000183442

chr8_+_14886452 3.51 ENSDART00000146589
sterol O-acyltransferase 1
chr10_+_26747755 3.46 ENSDART00000100329
coagulation factor IXb
chr6_-_32025225 3.38 ENSDART00000006417
phosphoglucomutase 1
chr5_+_23622177 3.30 ENSDART00000121504
connexin 27.5
chr6_-_58757131 3.28 ENSDART00000083582
sterol O-acyltransferase 2
chr21_+_33187992 3.26 ENSDART00000162745
ENSDART00000188388

chr23_+_36106790 3.22 ENSDART00000128533
homeobox C3a
chr2_+_24188502 3.19 ENSDART00000181955
ENSDART00000191706
ENSDART00000125909
microtubule associated protein 4 like
chr16_+_11585576 3.11 ENSDART00000172967
si:dkey-11o1.6
chr1_+_12177195 3.08 ENSDART00000146842
ENSDART00000142081
STRA6-like
chr14_-_3032016 3.04 ENSDART00000183461
ENSDART00000183035
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a
chr14_-_30387894 2.97 ENSDART00000176136
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr4_+_5531583 2.95 ENSDART00000137500
ENSDART00000042080
si:dkey-14d8.6
chr13_-_1408775 2.95 ENSDART00000049684
BCL2 associated athanogene 2
chr2_+_50862527 2.87 ENSDART00000169800
ENSDART00000158847
ENSDART00000160900
adenylate cyclase activating polypeptide 1a (pituitary) receptor type I
chr7_+_35075847 2.81 ENSDART00000193469
ENSDART00000037346
chymotrypsinogen B1
chr25_+_20089986 2.77 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr25_+_20091021 2.67 ENSDART00000187545
ENSDART00000053265
troponin I4b, tandem duplicate 2
chr5_+_7279104 2.65 ENSDART00000190014
si:ch73-72b7.1
chr15_-_3252727 2.62 ENSDART00000131173
stomatin (EPB72)-like 3a
chr3_-_39152478 2.60 ENSDART00000154550
si:dkeyp-57f11.2
chr8_-_40555340 2.56 ENSDART00000163348
NPC1 like intracellular cholesterol transporter 1
chr14_+_924876 2.49 ENSDART00000183908
myozenin 3a
chr23_-_11870962 2.47 ENSDART00000143481
si:dkey-178k16.1
chr22_+_15438872 2.47 ENSDART00000139800
glypican 5b
chr21_+_17880511 2.44 ENSDART00000080481
retinoid X receptor, alpha a
chr24_-_7321928 2.41 ENSDART00000167570
ENSDART00000045150
ARP3 actin related protein 3 homolog B
chr3_+_2669813 2.37 ENSDART00000014205

chr14_+_22113331 2.36 ENSDART00000109759
thioredoxin-related transmembrane protein 2a
chr6_-_11768198 2.35 ENSDART00000183463
membrane-associated ring finger (C3HC4) 7
chr7_-_5162292 2.31 ENSDART00000084218
zgc:195075
chr1_+_17593392 2.31 ENSDART00000078889
helt bHLH transcription factor
chr12_-_3753131 2.27 ENSDART00000129668
family with sequence similarity 57, member Bb
chr12_+_30586599 2.21 ENSDART00000124920
ENSDART00000126984
nebulin-related anchoring protein
chr20_-_47051996 2.19 ENSDART00000153330
DNA (cytosine-5-)-methyltransferase 3 alpha a
chr1_+_31110817 2.17 ENSDART00000137863
eukaryotic translation elongation factor 1 alpha 1b
chr19_-_29887629 2.16 ENSDART00000066123
karyopherin alpha 6 (importin alpha 7)
chr5_+_29820266 2.16 ENSDART00000146331
ENSDART00000098315
F11 receptor, tandem duplicate 2
chr2_+_57801960 2.15 ENSDART00000147966
si:dkeyp-68b7.10
chr19_+_5072918 2.15 ENSDART00000037126
enolase 2
chr19_-_5805923 2.13 ENSDART00000134340
si:ch211-264f5.8
chr16_+_34479064 2.10 ENSDART00000159965
si:ch211-255i3.4
chr7_+_48705227 2.06 ENSDART00000174034

chr23_+_45538932 2.01 ENSDART00000135602
si:ch73-290k24.6
chr23_-_44466257 2.00 ENSDART00000150126
si:ch1073-228j22.2
chr1_-_44701313 1.98 ENSDART00000193926
si:dkey-28b4.8
chr5_+_55984270 1.98 ENSDART00000047358
ENSDART00000138191
FK506 binding protein 6
chr16_+_20161805 1.96 ENSDART00000192146
chromosome 16 C2orf66 homolog
chr20_+_1960092 1.95 ENSDART00000191892

chr9_-_4606463 1.91 ENSDART00000179110
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr5_+_20147830 1.88 ENSDART00000098727
SV2 related protein a
chr2_-_17392799 1.86 ENSDART00000136470
ENSDART00000141188
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr11_-_42750626 1.86 ENSDART00000130640
si:ch73-106k19.5
chr7_+_14632157 1.86 ENSDART00000161264
neurotrophic tyrosine kinase, receptor, type 3b
chr19_-_18313303 1.85 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
chr9_-_28616436 1.84 ENSDART00000136985
si:ch73-7i4.2
chr5_+_20035284 1.83 ENSDART00000191808
small G protein signaling modulator 1a
chr23_+_16620801 1.82 ENSDART00000189859
ENSDART00000184578
syntaphilin b
chr19_-_28360033 1.82 ENSDART00000186994
si:dkey-261i16.5
chr1_-_12278056 1.82 ENSDART00000139336
ENSDART00000137463
complexin 2, like
chr5_-_68093169 1.81 ENSDART00000051849
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr24_+_14937205 1.80 ENSDART00000091735
docking protein 6
chr15_+_5277761 1.78 ENSDART00000153954
si:ch1073-166e24.4
chr18_-_8857137 1.77 ENSDART00000126331
proline-rich transmembrane protein 4
chr6_-_33023745 1.76 ENSDART00000156211
adenylate cyclase activating polypeptide 1b (pituitary) receptor type I
chr21_+_29179887 1.75 ENSDART00000161941
si:ch211-57b15.1
chr3_-_13946446 1.74 ENSDART00000171249
glutaryl-CoA dehydrogenase b
chr16_-_24642814 1.74 ENSDART00000153987
ENSDART00000154319
FXYD domain containing ion transport regulator 6 like
chr1_-_26063188 1.72 ENSDART00000168640
programmed cell death 4a
chr6_-_55585423 1.71 ENSDART00000157129
solute carrier family 12 (potassium/chloride transporter), member 5a
chr20_-_6532462 1.70 ENSDART00000054653
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr25_-_4713461 1.70 ENSDART00000155302
dopamine receptor D4a
chr5_+_25952340 1.69 ENSDART00000147188
transient receptor potential cation channel, subfamily M, member 3
chr20_-_23171430 1.68 ENSDART00000109234
spermatogenesis associated 18
chr21_-_13123176 1.67 ENSDART00000144866
ENSDART00000024616
family with sequence similarity 219, member Aa
chr21_+_26612777 1.66 ENSDART00000142667
estrogen-related receptor alpha
chr17_-_4252221 1.66 ENSDART00000152020
growth differentiation factor 3
chr8_+_39795918 1.66 ENSDART00000143413
si:ch211-170d8.2
chr14_-_36320506 1.65 ENSDART00000074639
epidermal growth factor
chr25_+_26895394 1.65 ENSDART00000155820
si:dkey-42p14.3
chr9_+_46644633 1.62 ENSDART00000160285
solute carrier family 4 (anion exchanger), member 3
chr19_+_31873308 1.62 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
chr9_+_2020667 1.58 ENSDART00000157818
limb and neural patterns a
chr1_+_25801648 1.58 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr17_-_43556415 1.57 ENSDART00000190102
ENSDART00000193156
5'-nucleotidase, cytosolic IAb
chr10_+_26926654 1.56 ENSDART00000078980
ENSDART00000100289
RAB1B, member RAS oncogene family b
chr2_+_10709710 1.55 ENSDART00000154712
ecotropic viral integration site 5a
chr12_+_18681477 1.55 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr25_+_2361721 1.54 ENSDART00000172905
zmp:0000000932
chr2_-_17393216 1.54 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr9_-_31596016 1.54 ENSDART00000142289
sodium leak channel, non-selective
chr18_+_5137241 1.54 ENSDART00000159601
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr9_-_48407408 1.53 ENSDART00000058248
zgc:172182
chr5_+_28497956 1.53 ENSDART00000191935
notochord formation related
chr2_+_50608099 1.52 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr25_-_10565006 1.52 ENSDART00000130608
ENSDART00000190212
galanin/GMAP prepropeptide
chr25_-_8030113 1.50 ENSDART00000104674
calcium/calmodulin-dependent protein kinase 1Db
chr15_-_7598294 1.49 ENSDART00000165898
glucan (1,4-alpha-), branching enzyme 1b
chr15_-_44077937 1.48 ENSDART00000110112
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr18_+_11506561 1.47 ENSDART00000121647
protein arginine methyltransferase 8
chr22_+_17205608 1.46 ENSDART00000181267
RAB3B, member RAS oncogene family
chr11_+_22374419 1.45 ENSDART00000174683
ENSDART00000170521
ENSDART00000193980
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr13_-_30713236 1.45 ENSDART00000112372
ENSDART00000142221
transmembrane protein 72
chr17_+_33495194 1.44 ENSDART00000033691
parathyroid hormone 2
chr13_+_17702522 1.43 ENSDART00000057913
si:dkey-27m7.4
chr13_-_37608441 1.43 ENSDART00000140230
zgc:123068
chr3_+_13624815 1.42 ENSDART00000161451
peptidoglycan recognition protein 6
chr2_-_2957970 1.42 ENSDART00000162505
si:ch1073-82l19.1
chr6_+_2195625 1.42 ENSDART00000155659
activin A receptor type 1Bb
chr16_-_24605969 1.41 ENSDART00000163305
ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr4_-_77506362 1.37 ENSDART00000174387
ENSDART00000181181

chr15_+_44366556 1.36 ENSDART00000133449
guanylate cyclase 1 soluble subunit alpha 2
chr9_-_51323545 1.35 ENSDART00000139316
solute carrier family 4, sodium bicarbonate transporter, member 10b
chr1_-_45920632 1.34 ENSDART00000140890
patatin-like phospholipase domain containing 6
chr14_+_3287740 1.33 ENSDART00000186290
caudal type homeobox 1a
chr16_+_14588141 1.33 ENSDART00000140469
ENSDART00000059984
ENSDART00000167411
ENSDART00000133566
DEP domain containing MTOR-interacting protein
chr20_+_26966725 1.33 ENSDART00000029781
AHA1, activator of heat shock protein ATPase homolog 1a
chr19_-_8768564 1.31 ENSDART00000170416
si:ch73-350k19.1
chr7_+_47243564 1.31 ENSDART00000098942
ENSDART00000162237
zinc finger protein 507
chr3_-_19091024 1.30 ENSDART00000188485
ENSDART00000110554
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr24_+_31655939 1.30 ENSDART00000187337

chr21_+_15824182 1.30 ENSDART00000065779
gonadotropin-releasing hormone 2
chr14_+_25465346 1.30 ENSDART00000173436
si:dkey-280e21.3
chr1_-_10647484 1.29 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
chr18_+_9615147 1.28 ENSDART00000160284
piccolo presynaptic cytomatrix protein b
chr14_-_26094172 1.28 ENSDART00000150131
melatonin receptor type 1A like
chr13_-_23264724 1.28 ENSDART00000051886
si:dkey-103j14.5
chr3_+_22036391 1.26 ENSDART00000147721
cell division cycle 27
chr20_+_19816465 1.26 ENSDART00000079613
cholinergic receptor, nicotinic, alpha 2b (neuronal)
chr10_+_21576909 1.25 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3
chr23_+_4646194 1.25 ENSDART00000092344

chr2_+_34572690 1.24 ENSDART00000077216
astrotactin 1
chr17_+_30751462 1.24 ENSDART00000154184
lipid droplet associated hydrolase
chr6_+_49412754 1.24 ENSDART00000027398
potassium voltage-gated channel, shaker-related subfamily, member 2a
chr7_+_65261576 1.23 ENSDART00000169566
beta-carotene oxygenase 1
chr3_-_40054615 1.23 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
lethal giant larvae homolog 1 (Drosophila)
chr19_-_5865766 1.23 ENSDART00000191007

chr8_+_3434146 1.23 ENSDART00000164426
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr4_-_2168805 1.22 ENSDART00000150039
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr24_+_33802528 1.22 ENSDART00000136040
ENSDART00000147499
ENSDART00000182322
autophagy related 9B
chr16_+_23598908 1.21 ENSDART00000131627
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_-_27685365 1.20 ENSDART00000188342
calcitonin/calcitonin-related polypeptide, alpha
chr9_+_49712868 1.20 ENSDART00000192969
ENSDART00000183310
cysteine and serine rich nuclear protein 3
chr9_-_34882516 1.19 ENSDART00000011163
acetylserotonin O-methyltransferase-like
chr7_+_35245607 1.19 ENSDART00000193422
ENSDART00000173888
autocrine motility factor receptor b
chr8_+_49778486 1.19 ENSDART00000131732
neurotrophic tyrosine kinase, receptor, type 2a
chr11_-_7078392 1.18 ENSDART00000112156
ENSDART00000188556
si:ch211-253b8.5
chr21_-_26071773 1.17 ENSDART00000141382
RAB34, member RAS oncogene family b
chr17_+_10090638 1.17 ENSDART00000169522
ENSDART00000160156
Sec23 homolog A, COPII coat complex component
chr4_-_48727718 1.17 ENSDART00000121499
zinc finger protein 1023
chr5_+_69981453 1.16 ENSDART00000143860
si:ch211-154e10.1
chr3_+_431208 1.16 ENSDART00000154296
ENSDART00000048733
si:ch73-308m11.1
si:dkey-167k11.5
chr2_+_44972720 1.16 ENSDART00000075146
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr2_+_56937548 1.15 ENSDART00000189308

chr3_+_52528606 1.14 ENSDART00000111510
prostaglandin E receptor 1c (subtype EP1)
chr2_-_14390627 1.14 ENSDART00000172367
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr3_-_32169754 1.13 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr3_-_24458281 1.12 ENSDART00000153993
BAI1-associated protein 2-like 2a
chr9_-_54248182 1.12 ENSDART00000129540
leucyl-tRNA synthetase a
chr10_-_2524917 1.11 ENSDART00000188642

chr23_+_14696043 1.10 ENSDART00000132037
si:rp71-79p20.2
chr22_-_12746539 1.10 ENSDART00000175374
phospholipase C, delta 4a
chr23_-_306796 1.09 ENSDART00000143125
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr6_-_31325400 1.09 ENSDART00000188869
DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_-_34294613 1.08 ENSDART00000191632

chr21_-_18648861 1.08 ENSDART00000112113
si:dkey-112m2.1
chr19_+_14059349 1.08 ENSDART00000166230
trophoblast glycoprotein a
chr25_-_8030425 1.08 ENSDART00000014964
calcium/calmodulin-dependent protein kinase 1Db
chr9_+_22656976 1.07 ENSDART00000136249
ENSDART00000139270
si:dkey-189g17.2
chr16_-_27174373 1.07 ENSDART00000166681
ferric-chelate reductase 1-like
chr14_+_36628131 1.07 ENSDART00000188625
ENSDART00000125345
si:dkey-237h12.3
chr17_-_6618574 1.05 ENSDART00000184486
si:ch211-189e2.3
chr10_+_5203532 1.05 ENSDART00000165018
CDC42 small effector 2
chr1_+_47178529 1.05 ENSDART00000158432
ENSDART00000074450
ENSDART00000137448
MORC family CW-type zinc finger 3b
chr24_+_9178064 1.04 ENSDART00000142971
discs, large (Drosophila) homolog-associated protein 1b
chr10_-_8053385 1.03 ENSDART00000142714
si:ch211-251f6.7

Network of associatons between targets according to the STRING database.

First level regulatory network of meox2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:2000257 regulation of protein activation cascade(GO:2000257)
1.4 12.5 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
1.0 5.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.9 4.5 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.8 8.3 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.6 3.1 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.5 1.6 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.5 1.6 GO:1903373 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.5 2.0 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.5 26.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.5 3.0 GO:1902837 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.5 7.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.5 1.4 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.4 11.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.4 1.6 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 1.2 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.4 2.2 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.4 1.1 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.4 1.8 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.4 1.8 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.4 1.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 2.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 0.7 GO:0046635 positive regulation of alpha-beta T cell activation(GO:0046635)
0.3 1.7 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.3 4.5 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.3 0.9 GO:0060292 long term synaptic depression(GO:0060292)
0.3 1.7 GO:0016048 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.3 3.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 1.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.3 2.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.3 2.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 1.7 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.2 2.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 0.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.2 1.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 1.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.2 0.6 GO:0007567 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.2 0.8 GO:0006531 aspartate metabolic process(GO:0006531)
0.2 1.0 GO:0033292 T-tubule organization(GO:0033292)
0.2 1.0 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.2 0.6 GO:0097435 fibril organization(GO:0097435)
0.2 2.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.7 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.2 0.8 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.2 1.1 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 2.2 GO:0050892 intestinal absorption(GO:0050892)
0.2 0.5 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.1 0.4 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 1.3 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 0.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.7 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 3.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.4 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 1.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 1.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.2 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.7 GO:0051967 spinal cord motor neuron cell fate specification(GO:0021520) negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 1.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.9 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.1 0.7 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 3.4 GO:0032526 response to retinoic acid(GO:0032526)
0.1 1.3 GO:0035094 response to nicotine(GO:0035094)
0.1 1.2 GO:0030431 sleep(GO:0030431)
0.1 1.2 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.8 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 0.9 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.1 1.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.6 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 2.2 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 0.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 1.3 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.3 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 4.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 2.9 GO:0050821 protein stabilization(GO:0050821)
0.1 0.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 5.0 GO:0006414 translational elongation(GO:0006414)
0.1 0.6 GO:0031646 positive regulation of myelination(GO:0031643) positive regulation of neurological system process(GO:0031646)
0.1 2.9 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.4 GO:1900044 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 1.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.8 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 1.3 GO:0099565 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.1 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 1.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.4 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 1.0 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 1.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 2.0 GO:0019915 lipid storage(GO:0019915)
0.1 0.1 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1 0.8 GO:0032098 regulation of appetite(GO:0032098)
0.1 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 2.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.7 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of nucleotide metabolic process(GO:0045980) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372) negative regulation of purine nucleotide metabolic process(GO:1900543)
0.0 3.5 GO:0007596 blood coagulation(GO:0007596)
0.0 0.6 GO:0030317 sperm motility(GO:0030317)
0.0 0.5 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 1.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)
0.0 3.5 GO:0006006 glucose metabolic process(GO:0006006)
0.0 2.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.5 GO:0032264 IMP salvage(GO:0032264)
0.0 1.8 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.6 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 1.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.4 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 2.6 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 2.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.7 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.6 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 1.6 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.5 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 1.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 1.1 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 1.0 GO:0007548 sex differentiation(GO:0007548)
0.0 0.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.6 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.6 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 1.2 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.6 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 1.7 GO:0010506 regulation of autophagy(GO:0010506)
0.0 2.1 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 1.0 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.4 GO:0043506 activation of JUN kinase activity(GO:0007257) regulation of JUN kinase activity(GO:0043506) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.9 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.4 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.6 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.0 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.4 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.2 GO:0001754 eye photoreceptor cell differentiation(GO:0001754)
0.0 2.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 1.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.0 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 1.2 GO:0051260 protein homooligomerization(GO:0051260)
0.0 1.0 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 2.0 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.6 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.1 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 1.6 GO:0042391 regulation of membrane potential(GO:0042391)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.9 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
1.3 6.6 GO:0030314 junctional membrane complex(GO:0030314)
0.8 8.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 4.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.6 26.2 GO:0005861 troponin complex(GO:0005861)
0.5 1.6 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.3 2.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 0.8 GO:0010369 chromocenter(GO:0010369)
0.2 1.5 GO:0071986 Ragulator complex(GO:0071986)
0.2 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 1.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 1.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.0 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.0 GO:0016011 dystroglycan complex(GO:0016011)
0.1 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 13.5 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.1 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 11.1 GO:0016459 myosin complex(GO:0016459)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.8 GO:0043195 terminal bouton(GO:0043195)
0.1 1.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 3.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.0 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 19.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.1 GO:0031514 motile cilium(GO:0031514)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.5 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
1.9 5.7 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.8 8.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.7 7.4 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.6 7.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.5 3.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 3.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.5 2.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.5 1.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.4 1.7 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.4 1.3 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.4 3.0 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.4 2.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.4 1.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.4 3.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.4 1.5 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.4 1.8 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.3 2.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 3.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 2.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 1.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 3.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.3 2.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 2.6 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.0 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 1.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 1.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 2.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 1.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 5.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.2 0.6 GO:0004990 oxytocin receptor activity(GO:0004990)
0.2 0.8 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 1.0 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.2 1.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.2 0.9 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 0.7 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.2 4.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 7.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.9 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 3.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 1.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 2.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 3.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 2.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 3.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:0072570 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 0.3 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.7 GO:0031779 melanocortin receptor binding(GO:0031779)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.4 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 3.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.4 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.1 0.7 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.1 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.6 GO:0005549 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.1 0.6 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 1.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.5 GO:0038187 pattern recognition receptor activity(GO:0038187)
0.1 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.2 GO:0045159 myosin II binding(GO:0045159)
0.1 1.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.7 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 7.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 2.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 2.4 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 0.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.9 GO:0016208 AMP binding(GO:0016208)
0.1 0.9 GO:0019870 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 2.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 5.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 11.5 GO:0003774 motor activity(GO:0003774)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.5 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 1.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 2.6 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.9 GO:0042562 hormone binding(GO:0042562)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 2.7 GO:0008083 growth factor activity(GO:0008083)
0.0 1.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 1.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 1.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 3.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.5 11.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 2.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 4.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 3.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 1.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 1.0 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 4.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.7 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.4 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 3.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules