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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for mixl1+mxtx1+sebox

Z-value: 0.55

Motif logo

Transcription factors associated with mixl1+mxtx1+sebox

Gene Symbol Gene ID Gene Info
ENSDARG00000042526 SEBOX homeobox
ENSDARG00000069252 Mix paired-like homeobox
ENSDARG00000069382 mix-type homeobox gene 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mxtx1dr11_v1_chr13_-_21660203_21660203-0.171.1e-01Click!
mixl1dr11_v1_chr20_-_43723860_437238600.056.3e-01Click!
seboxdr11_v1_chr5_+_67371650_67371650-0.037.4e-01Click!

Activity profile of mixl1+mxtx1+sebox motif

Sorted Z-values of mixl1+mxtx1+sebox motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_41494831 6.31 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr6_-_54826061 4.21 ENSDART00000149982
troponin I type 1b (skeletal, slow)
chr25_+_31276842 3.75 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr2_+_6253246 2.52 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr19_-_5103141 2.22 ENSDART00000150952
triosephosphate isomerase 1a
chr8_+_21353878 2.20 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr8_-_14126646 2.14 ENSDART00000027225
biglycan a
chr2_+_33326522 2.13 ENSDART00000056655
Kruppel-like factor 17
chr6_+_50381665 2.02 ENSDART00000141128
cytochrome c-1
chr9_-_21918963 2.00 ENSDART00000090782
LIM domain 7a
chr10_-_7756865 1.94 ENSDART00000114373
ENSDART00000125407
ENSDART00000016317
lysyl oxidase a
chr24_-_40744672 1.92 ENSDART00000160672

chr21_+_25777425 1.84 ENSDART00000021620
claudin d
chr21_-_11654422 1.84 ENSDART00000081614
ENSDART00000132699
calpastatin
chr6_-_3982783 1.72 ENSDART00000171944
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr17_+_16046314 1.70 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr19_+_2631565 1.67 ENSDART00000171487
family with sequence similarity 126, member A
chr20_-_23426339 1.67 ENSDART00000004625
zygote arrest 1
chr16_+_47207691 1.61 ENSDART00000062507
islet cell autoantigen 1
chr11_-_1550709 1.61 ENSDART00000110097
si:ch73-303b9.1
chr1_-_18811517 1.60 ENSDART00000142026
si:dkey-167i21.2
chr12_+_24952902 1.58 ENSDART00000189086
ENSDART00000014868
calmodulin 3a (phosphorylase kinase, delta)
chr21_+_34088377 1.57 ENSDART00000170070
myotubularin related protein 1b
chr17_+_16046132 1.57 ENSDART00000155005
si:ch73-204p21.2
chr22_-_15593824 1.55 ENSDART00000123125
tropomyosin 4a
chr8_+_45334255 1.55 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr23_-_31913069 1.53 ENSDART00000135526
mitochondrial fission regulator 2
chr24_+_16547035 1.51 ENSDART00000164319
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr20_-_20931197 1.50 ENSDART00000152726
BTB (POZ) domain containing 6b
chr12_-_14143344 1.49 ENSDART00000152742
bucky ball 2-like
chr21_-_39177564 1.49 ENSDART00000065143
unc-119 homolog b (C. elegans)
chr19_-_32710922 1.45 ENSDART00000004034
hippocalcin
chr21_-_32060993 1.43 ENSDART00000131651
si:ch211-160j14.2
chr5_+_35786141 1.41 ENSDART00000022043
ENSDART00000127383
StAR-related lipid transfer (START) domain containing 8
chr22_+_16535575 1.41 ENSDART00000083063
T-cell acute lymphocytic leukemia 1
chr7_-_71389375 1.40 ENSDART00000128928

chr25_+_3306620 1.38 ENSDART00000182085
ENSDART00000034704
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr3_-_30685401 1.36 ENSDART00000151097
si:ch211-51c14.1
chr20_+_52554352 1.35 ENSDART00000153217
ENSDART00000145230
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr10_-_21362320 1.32 ENSDART00000189789
avidin
chr23_+_11285662 1.31 ENSDART00000111028
cell adhesion molecule L1-like a
chr18_-_40708537 1.30 ENSDART00000077577
si:ch211-132b12.8
chr23_+_31913292 1.29 ENSDART00000136910
armadillo repeat containing 1, like
chr18_+_24921587 1.29 ENSDART00000191345
repulsive guidance molecule family member a
chr10_-_21362071 1.25 ENSDART00000125167
avidin
chr21_+_34088110 1.25 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
myotubularin related protein 1b
chr16_-_29387215 1.20 ENSDART00000148787
S100 calcium binding protein A1
chr15_-_9272328 1.19 ENSDART00000172114
calmodulin 2a (phosphorylase kinase, delta)
chr18_+_19456648 1.17 ENSDART00000079695
zwilch kinetochore protein
chr23_+_44741500 1.16 ENSDART00000166421
ATPase Na+/K+ transporting subunit beta 2a
chr14_+_22113331 1.13 ENSDART00000109759
thioredoxin-related transmembrane protein 2a
chr23_-_31913231 1.12 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr15_+_1534644 1.10 ENSDART00000130413
structural maintenance of chromosomes 4
chr21_-_40174647 1.10 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
solute carrier organic anion transporter family, member 2B1
chr24_+_12835935 1.10 ENSDART00000114762
nanog homeobox
chr7_+_23292133 1.09 ENSDART00000134489
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1
chr10_-_25217347 1.07 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr23_+_31912882 1.06 ENSDART00000140505
armadillo repeat containing 1, like
chr5_+_52167986 1.06 ENSDART00000162256
ENSDART00000073626
solute carrier family 14 (urea transporter), member 2
chr7_+_20503344 1.05 ENSDART00000157699
si:dkey-19b23.12
chr1_+_8694196 1.03 ENSDART00000025604
zgc:77849
chr20_-_20930926 1.03 ENSDART00000123909
BTB (POZ) domain containing 6b
chr6_+_21001264 1.02 ENSDART00000044519
ENSDART00000151278
connexin 44.2
chr15_-_43284021 1.02 ENSDART00000041677
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr6_-_14292307 1.01 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr6_+_50381347 1.00 ENSDART00000055504
cytochrome c-1
chr5_+_37903790 0.99 ENSDART00000162470
transmembrane protease, serine 4b
chr16_-_42056137 0.95 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr16_-_17347727 0.95 ENSDART00000144392
zyxin
chr25_+_7504314 0.93 ENSDART00000163231
interferon induced transmembrane protein 5
chr21_+_15592426 0.93 ENSDART00000138207
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr22_+_18477934 0.90 ENSDART00000132684
cartilage intermediate layer protein 2
chr13_+_38430466 0.90 ENSDART00000132691
adhesion G protein-coupled receptor B3
chr16_+_29509133 0.89 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr23_-_25135046 0.88 ENSDART00000184844
ENSDART00000103989
isocitrate dehydrogenase 3 (NAD+) gamma
chr12_+_10631266 0.85 ENSDART00000161455
colony stimulating factor 3 (granulocyte) a
chr22_-_19552796 0.84 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
chr17_+_23298928 0.83 ENSDART00000153652
zgc:165461
chr22_+_4488454 0.81 ENSDART00000170620
cortexin 1
chr3_-_16719244 0.80 ENSDART00000055859
polymerase (DNA directed), delta 1, catalytic subunit
chr5_-_68093169 0.76 ENSDART00000051849
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr22_-_2937503 0.75 ENSDART00000092991
ENSDART00000131110
phosphatidylinositol glycan anchor biosynthesis, class X
chr22_-_20166660 0.75 ENSDART00000085913
ENSDART00000188241
BTB (POZ) domain containing 2a
chr20_-_52338782 0.75 ENSDART00000109735
ENSDART00000132941
si:ch1073-287p18.1
chr9_+_29548195 0.74 ENSDART00000176057
ring finger protein 17
chr24_+_1023839 0.73 ENSDART00000082526
zgc:111976
chr6_-_12172424 0.71 ENSDART00000109344
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr13_+_24750078 0.69 ENSDART00000021053
collagen, type XVII, alpha 1b
chr8_+_50953776 0.68 ENSDART00000013870
zgc:56596
chr14_-_22113600 0.68 ENSDART00000113752
si:dkey-6i22.5
chr8_+_7144066 0.68 ENSDART00000146306
solute carrier family 6 (neurotransmitter transporter), member 6a
chr1_-_55248496 0.67 ENSDART00000098615
nanos homolog 3
chr20_-_14114078 0.67 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr17_-_16422654 0.66 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr3_-_39695856 0.66 ENSDART00000148247
B9 protein domain 1
chr21_-_40173821 0.66 ENSDART00000180667
solute carrier organic anion transporter family, member 2B1
chr7_+_56098590 0.66 ENSDART00000098453
cadherin 15, type 1, M-cadherin (myotubule)
chr24_+_21540842 0.65 ENSDART00000091529
WAS protein family, member 3b
chr11_-_30634286 0.64 ENSDART00000191019
zgc:153665
chr24_+_40860320 0.64 ENSDART00000161351
golgi reassembly stacking protein 1b
chr7_-_51773166 0.64 ENSDART00000054591
bone morphogenetic protein 15
chr1_+_35985813 0.63 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
chr9_-_31278048 0.63 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr5_+_36611128 0.63 ENSDART00000097684
neuro-oncological ventral antigen 1
chr11_-_35171162 0.62 ENSDART00000017393
TRAF-interacting protein
chr8_+_49117518 0.62 ENSDART00000079631
RAD21 cohesin complex component like 1
chr15_-_23376541 0.61 ENSDART00000078570
C1q and TNF related 5
chr8_+_2757821 0.61 ENSDART00000051403
ENSDART00000160551
SH3-domain GRB2-like endophilin B2a
chr7_+_26649319 0.61 ENSDART00000173823
ENSDART00000101053
tumor protein p53 inducible protein 11a
chr4_-_5455506 0.61 ENSDART00000156593
ENSDART00000154676
si:dkey-14d8.22
chr24_+_19415124 0.60 ENSDART00000186931
sulfatase 1
chr21_-_35419486 0.59 ENSDART00000138529
si:dkeyp-23e4.3
chr1_+_52929185 0.58 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr6_-_50203682 0.57 ENSDART00000083999
ENSDART00000143050
RALY heterogeneous nuclear ribonucleoprotein
chr14_+_45406299 0.56 ENSDART00000173142
ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr10_+_6884627 0.55 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr13_+_35637048 0.53 ENSDART00000085037
thrombospondin 2a
chr12_-_30359498 0.51 ENSDART00000152981
ENSDART00000189988
tudor domain containing 1
chr1_+_18811679 0.48 ENSDART00000078610
solute carrier family 25, member 51a
chr3_-_30488063 0.48 ENSDART00000055393
ENSDART00000151367
mediator complex subunit 25
chr3_-_39696066 0.48 ENSDART00000015393
B9 protein domain 1
chr14_-_33105434 0.48 ENSDART00000163795
discs, large homolog 3 (Drosophila)
chr11_+_29770966 0.47 ENSDART00000088624
ENSDART00000124471
retinitis pigmentosa GTPase regulator b
chr21_+_13366353 0.47 ENSDART00000151630
si:ch73-62l21.1
chr16_+_13883872 0.46 ENSDART00000101304
ENSDART00000136005
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr1_-_26444075 0.46 ENSDART00000125690
integrator complex subunit 12
chr3_+_26244353 0.45 ENSDART00000103733
ATPase family, AAA domain containing 5a
chr5_+_4436405 0.45 ENSDART00000167969

chr1_-_29139141 0.44 ENSDART00000075546
ENSDART00000133246
heat shock transcription factor 2 binding protein
chr11_+_38280454 0.43 ENSDART00000171496
si:dkey-166c18.1
chr6_+_102506 0.42 ENSDART00000172678
low density lipoprotein receptor b
chr19_-_30524952 0.42 ENSDART00000103506
hippocalcin like 4
chr24_-_37640705 0.42 ENSDART00000066583
zgc:112496
chr11_+_33818179 0.42 ENSDART00000109418
speckle-type POZ protein-like b
chr8_+_36500308 0.41 ENSDART00000098701
solute carrier family 7, member 4
chr11_-_41220794 0.39 ENSDART00000192895
mitochondrial ribosomal protein S16
chr10_+_15777258 0.38 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr21_+_44857293 0.38 ENSDART00000134365
ENSDART00000168217
ENSDART00000065083
follistatin-like 4
chr21_-_22827548 0.38 ENSDART00000079161
angiopoietin-like 5
chr17_-_20118145 0.38 ENSDART00000149737
ENSDART00000165606
ryanodine receptor 2b (cardiac)
chr16_+_5774977 0.37 ENSDART00000134202
cholecystokinin a
chr2_+_50608099 0.37 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chrM_+_3803 0.37 ENSDART00000093596
NADH dehydrogenase 1, mitochondrial
chr14_+_33329761 0.36 ENSDART00000161138
sosondowah ankyrin repeat domain family d
chr11_-_7261717 0.36 ENSDART00000128959
zgc:113223
chr20_-_45661049 0.36 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr15_+_36309070 0.36 ENSDART00000157034
geminin coiled-coil domain containing
chr24_-_6078222 0.34 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr13_+_25486608 0.34 ENSDART00000057689
BCL2 associated athanogene 3
chr17_-_31695217 0.34 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr8_+_41037541 0.33 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr20_-_16171297 0.33 ENSDART00000012476
cytochrome c oxidase assembly factor 7
chr19_-_20113696 0.33 ENSDART00000188813
neuropeptide Y
chr24_+_9412450 0.33 ENSDART00000132724
si:ch211-285f17.1
chr17_-_31639845 0.33 ENSDART00000154196
zinc finger protein 839
chr20_-_32270866 0.32 ENSDART00000153140
armadillo repeat containing 2
chr22_-_12160283 0.30 ENSDART00000146785
ENSDART00000128176
transmembrane protein 163b
chr7_+_28612671 0.30 ENSDART00000019991
solute carrier family 7, member 6 opposite strand
chr16_+_21330634 0.30 ENSDART00000191285
ENSDART00000183267
oxysterol binding protein-like 3b
chr10_+_6884123 0.30 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr25_+_11456696 0.29 ENSDART00000171408
si:ch73-141f14.1
chr4_+_9400012 0.29 ENSDART00000191960
transmembrane and tetratricopeptide repeat containing 1
chr19_+_43297546 0.29 ENSDART00000168002
lysosomal protein transmembrane 5
chr3_+_45364849 0.28 ENSDART00000153974
ubiquitin-conjugating enzyme E2Ia
chr11_+_31864921 0.28 ENSDART00000180252
diaphanous-related formin 3
chr2_-_32384683 0.28 ENSDART00000182942
ENSDART00000141757
upstream binding transcription factor, like
chr14_-_8940499 0.28 ENSDART00000129030
zgc:153681
chr2_-_30668580 0.28 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr23_+_40460333 0.27 ENSDART00000184658
SOGA family member 3b
chr25_-_2723682 0.27 ENSDART00000113382
ADP-dependent glucokinase
chr9_+_25776971 0.27 ENSDART00000146011
zinc finger E-box binding homeobox 2a
chr9_-_746317 0.27 ENSDART00000129632
ENSDART00000130720
ubiquitin specific peptidase 37
chr16_-_43344859 0.25 ENSDART00000058680
proteasome subunit alpha 2
chr19_-_19379084 0.25 ENSDART00000165206
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr15_-_34785594 0.24 ENSDART00000154256
gamma-aminobutyric acid (GABA) B receptor, 1a
chr24_-_24724233 0.24 ENSDART00000127044
ENSDART00000012399
armadillo repeat containing 1
chr19_+_10339538 0.24 ENSDART00000151808
ENSDART00000151235
recoverin 3
chr19_+_40069524 0.23 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chrM_+_8130 0.22 ENSDART00000093609
cytochrome c oxidase II, mitochondrial
chr21_+_42226113 0.22 ENSDART00000170362
gamma-aminobutyric acid type A receptor beta2 subunit
chr12_+_2446837 0.22 ENSDART00000112032
si:dkey-191m6.4
chr11_-_30158191 0.22 ENSDART00000155278
ENSDART00000156121
Scm polycomb group protein like 2
chr20_-_45062514 0.22 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr22_-_10121880 0.21 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr1_+_21731382 0.21 ENSDART00000054395
paired box 5
chr7_+_34592526 0.21 ENSDART00000173959
formin homology 2 domain containing 1
chr7_-_72261721 0.20 ENSDART00000172229
RAS guanyl releasing protein 2
chr14_+_6962271 0.20 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr4_+_9177997 0.20 ENSDART00000057254
ENSDART00000154614
nuclear transcription factor Y, beta a
chr10_+_43039947 0.20 ENSDART00000193434
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr8_-_25033681 0.19 ENSDART00000003493
nuclear transcription factor Y, alpha, like
chr12_-_4408828 0.18 ENSDART00000152447
si:ch211-173d10.1
chr8_-_19216657 0.18 ENSDART00000135096
ENSDART00000135869
ENSDART00000145951
si:ch73-222f22.2
si:ch73-222f22.2
chr5_+_28770273 0.17 ENSDART00000114473
TRAF-type zinc finger domain containing 1
chr18_-_29896367 0.16 ENSDART00000191303
C-x(9)-C motif containing 2
chr8_-_16406440 0.16 ENSDART00000034004
Fas (TNFRSF6) associated factor 1
chr19_-_30510259 0.15 ENSDART00000135128
ENSDART00000186169
ENSDART00000182974
ENSDART00000187797
BCL2 associated athanogene 6, like
chr3_+_33341640 0.15 ENSDART00000186352
peptide YYa
chr22_-_14739491 0.15 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr21_-_36453594 0.14 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8

Network of associatons between targets according to the STRING database.

First level regulatory network of mixl1+mxtx1+sebox

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0048785 hatching gland development(GO:0048785)
0.6 2.2 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.5 1.4 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.4 1.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 1.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 3.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3 1.8 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.3 1.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 0.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 3.5 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.8 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 1.5 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 0.9 GO:0016322 neuron remodeling(GO:0016322)
0.2 1.7 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 0.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.6 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.2 8.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 0.8 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) C4-dicarboxylate transport(GO:0015740) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 2.2 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.7 GO:0000012 single strand break repair(GO:0000012)
0.1 1.2 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 1.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 7.7 GO:0006414 translational elongation(GO:0006414)
0.1 1.9 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.3 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.9 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.8 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.3 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.3 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 1.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.6 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 3.0 GO:0009060 aerobic respiration(GO:0009060)
0.1 0.5 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 1.6 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.4 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.6 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.2 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 1.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 2.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.7 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.0 0.3 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 2.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.5 GO:0060021 palate development(GO:0060021)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.2 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 1.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:0060114 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.7 GO:0072348 sulfur compound transport(GO:0072348)
0.0 2.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.5 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.5 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.0 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.0 1.2 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 1.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.1 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.0 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 1.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 8.0 GO:0005861 troponin complex(GO:0005861)
0.2 0.7 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.2 0.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.5 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.0 GO:0035060 brahma complex(GO:0035060)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.2 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.6 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 1.6 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.5 GO:0071546 pi-body(GO:0071546)
0.1 1.5 GO:0043186 P granule(GO:0043186)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0097189 apoptotic body(GO:0097189)
0.0 0.2 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 1.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.3 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.0 1.6 GO:0005884 actin filament(GO:0005884)
0.0 2.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 4.1 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.6 2.2 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.5 2.6 GO:0009374 biotin binding(GO:0009374)
0.3 2.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 1.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 2.5 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 1.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 0.7 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.2 1.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 0.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 7.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.0 GO:0032190 acrosin binding(GO:0032190)
0.2 0.8 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 1.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.5 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 1.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.6 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.4 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.8 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.3 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.5 GO:0034584 piRNA binding(GO:0034584)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 3.2 GO:0009055 electron carrier activity(GO:0009055)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.1 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.0 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.9 GO:0042802 identical protein binding(GO:0042802)
0.0 0.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 2.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 5.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases