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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for msx2b

Z-value: 0.61

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Transcription factors associated with msx2b

Gene Symbol Gene ID Gene Info
ENSDARG00000101023 muscle segment homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx2bdr11_v1_chr21_-_41147818_41147818-0.223.1e-02Click!

Activity profile of msx2b motif

Sorted Z-values of msx2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_37178271 6.11 ENSDART00000161771
inter-alpha-trypsin inhibitor heavy chain 3b
chr13_+_23988442 5.27 ENSDART00000010918
angiotensinogen
chr13_+_8958438 4.59 ENSDART00000165721
ENSDART00000169398
3-hydroxyanthranilate 3,4-dioxygenase
chr10_+_25726694 3.91 ENSDART00000140308
UDP glucuronosyltransferase 5 family, polypeptide D1
chr14_+_1007169 3.63 ENSDART00000172676
coagulation factor VIII, procoagulant component
chr21_+_38002879 3.35 ENSDART00000065183
claudin 2
chr8_+_40477264 3.20 ENSDART00000085559
glucokinase (hexokinase 4)
chr15_-_34408777 3.05 ENSDART00000139934
alkylglycerol monooxygenase
chr4_+_14900042 2.66 ENSDART00000018261
aldo-keto reductase family 1, member B1 (aldose reductase)
chr14_-_11456724 2.55 ENSDART00000110424
si:ch211-153b23.4
chr18_+_7073130 2.17 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
chr20_+_38031439 2.17 ENSDART00000153208
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr24_+_26017094 2.15 ENSDART00000137851
transferrin receptor 1b
chr5_+_24179307 1.98 ENSDART00000051552
mannose-P-dolichol utilization defect 1a
chr13_+_23132666 1.98 ENSDART00000164639
sorbin and SH3 domain containing 1
chr10_-_25217347 1.89 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr8_+_20140321 1.84 ENSDART00000012120
acyl-CoA synthetase bubblegum family member 2
chr9_-_24031461 1.83 ENSDART00000021218
ribulose-5-phosphate-3-epimerase
chr10_+_6013076 1.71 ENSDART00000167613
ENSDART00000159216
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr20_+_36628059 1.63 ENSDART00000062898
epoxide hydrolase 1, microsomal (xenobiotic)
chr5_-_62317496 1.62 ENSDART00000180089
zgc:85789
chr13_-_4223955 1.60 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr7_+_6990510 1.60 ENSDART00000138948
copper chaperone for superoxide dismutase
chr18_-_26715655 1.59 ENSDART00000181497
MALT paracaspase 3
chr5_-_38777852 1.51 ENSDART00000131603
si:dkey-58f10.4
chr15_+_17031111 1.50 ENSDART00000175378
perilipin 2
chr12_-_42368296 1.49 ENSDART00000171075
zgc:111868
chr21_-_35082715 1.46 ENSDART00000146454
adrenoceptor beta 2, surface b
chr2_-_24398324 1.43 ENSDART00000165226
zgc:154006
chr7_-_61901695 1.32 ENSDART00000110328
SH3 domain and tetratricopeptide repeats 1
chr21_+_10712823 1.26 ENSDART00000123476
lectin, mannose-binding, 1
chr15_+_17074185 1.23 ENSDART00000046648
cleft lip and palate associated transmembrane protein 1
chr19_-_22346582 1.21 ENSDART00000045675
ENSDART00000169065
solute carrier family 52 (riboflavin transporter), member 2
zgc:109744
chr20_-_23426339 1.20 ENSDART00000004625
zygote arrest 1
chr17_+_8542203 1.17 ENSDART00000158873

chr5_-_9216758 1.17 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr15_+_7064819 1.12 ENSDART00000155268
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr7_-_59210882 1.08 ENSDART00000170330
ENSDART00000158996
N-acetylglucosamine kinase
chr16_+_41570653 1.08 ENSDART00000102665
asteroid homolog 1a
chr2_-_50225411 1.07 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr13_+_28747934 1.07 ENSDART00000160176
ENSDART00000101633
ENSDART00000136318
prominin 2
chr1_+_43686251 1.04 ENSDART00000074604
ENSDART00000137791
CDGSH iron sulfur domain 2
chr15_+_17030941 1.03 ENSDART00000062069
perilipin 2
chr2_+_42871831 1.03 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr2_-_10600950 1.00 ENSDART00000160216

chr16_-_50897887 1.00 ENSDART00000156985
si:ch73-90p23.1
chr9_+_41156818 0.98 ENSDART00000105764
ENSDART00000147052
signal transducer and activator of transcription 4
chr15_-_19051152 0.98 ENSDART00000186453
Rho GTPase activating protein 32a
chr17_-_18898115 0.97 ENSDART00000028044
galactosylceramidase b
chr6_+_54239625 0.93 ENSDART00000149542
protein kinase C and casein kinase substrate in neurons 1b
chr11_-_44484952 0.91 ENSDART00000166674
ENSDART00000188016
mitofusin 1b
chr25_+_30442389 0.85 ENSDART00000003346
programmed cell death 2-like
chr14_+_35369979 0.85 ENSDART00000144702
ENSDART00000169712
clathrin interactor 1a
chr22_-_16755885 0.85 ENSDART00000036467
PATJ, crumbs cell polarity complex component
chr12_-_3992839 0.84 ENSDART00000126100
si:ch211-136m16.8
chr18_-_16907436 0.83 ENSDART00000146464
switching B cell complex subunit SWAP70b
chr3_-_13509283 0.83 ENSDART00000166832
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr14_-_8453192 0.81 ENSDART00000136947
eukaryotic translation initiation factor 1A domain containing
chr23_-_44903048 0.79 ENSDART00000149103
FH2 domain containing 5
chr19_-_7441948 0.79 ENSDART00000003544
GA binding protein transcription factor, beta subunit 2a
chr19_-_12392819 0.78 ENSDART00000052239
protein tyrosine phosphatase, non-receptor type 2, b
chr11_+_17984167 0.77 ENSDART00000020283
ENSDART00000188329
RNA pseudouridylate synthase domain containing 4
chr4_-_5455506 0.77 ENSDART00000156593
ENSDART00000154676
si:dkey-14d8.22
chr6_+_8630355 0.75 ENSDART00000161749
ENSDART00000193976
thrombospondin-type laminin G domain and EAR repeats a
chr19_+_12406583 0.75 ENSDART00000013865
ENSDART00000151535
SEH1-like (S. cerevisiae)
chr17_+_21477892 0.72 ENSDART00000155309
phospholipase A2, group IVF, tandem duplicate 2
chr6_+_8626427 0.71 ENSDART00000193660
thrombospondin-type laminin G domain and EAR repeats a
chr23_-_14990865 0.69 ENSDART00000147799
ndrg family member 3b
chr7_+_33145529 0.68 ENSDART00000052387
intelectin 2
chr25_-_28926631 0.67 ENSDART00000112850
electron transfer flavoprotein beta subunit lysine methyltransferase
chr11_-_6880725 0.66 ENSDART00000007204
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr22_-_18164671 0.66 ENSDART00000014057
regulatory factor X-associated ankyrin-containing protein
chr11_+_17984354 0.66 ENSDART00000179986
RNA pseudouridylate synthase domain containing 4
chr2_-_26590628 0.66 ENSDART00000025120
NDC1 transmembrane nucleoporin
chr8_+_23738122 0.63 ENSDART00000062983
ribosomal protein L10a
chr22_-_18164835 0.63 ENSDART00000143189
regulatory factor X-associated ankyrin-containing protein
chr3_+_22935183 0.60 ENSDART00000157378
histone deacetylase 5
chr3_-_44059902 0.60 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
interleukin 4 receptor, tandem duplicate 1
chr1_-_24462544 0.58 ENSDART00000184421
ENSDART00000184987
ENSDART00000126950
SH3 domain containing 19
chr4_+_12966640 0.58 ENSDART00000113357
von Hippel-Lindau tumor suppressor like
chr6_+_6828167 0.58 ENSDART00000181284
si:ch211-85n16.4
chr10_-_16065185 0.56 ENSDART00000187266
si:dkey-184a18.5
chr7_-_64971839 0.55 ENSDART00000164682
SIN3-HDAC complex associated factor, like
chr17_+_1496107 0.49 ENSDART00000187804

chr22_-_15717897 0.49 ENSDART00000008424
MALT paracaspase 2
chr13_-_36050303 0.49 ENSDART00000134955
ENSDART00000139087
legumain
chr7_+_15313443 0.47 ENSDART00000045385
mesoderm posterior ba
chr15_-_17813680 0.46 ENSDART00000158556

chr1_-_45213565 0.46 ENSDART00000145757
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr4_+_17671164 0.45 ENSDART00000040445
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr2_+_37176814 0.45 ENSDART00000048277
ENSDART00000176827
coatomer protein complex, subunit alpha
chr11_+_25539698 0.45 ENSDART00000035602
CXXC finger protein 1b
chr8_-_11324143 0.44 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr21_-_5205617 0.44 ENSDART00000145554
ENSDART00000045284
ribosomal protein L37
chr13_-_25819825 0.43 ENSDART00000077612
v-rel avian reticuloendotheliosis viral oncogene homolog
chr20_+_35484070 0.41 ENSDART00000026234
ENSDART00000141675
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2
chr3_-_33427803 0.41 ENSDART00000075495
ribosomal protein L23
chr22_+_1887750 0.40 ENSDART00000180917
si:dkey-15h8.17
chr12_+_10115964 0.40 ENSDART00000152369
si:dkeyp-118b1.2
chr8_-_1838315 0.40 ENSDART00000114476
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr6_-_45869127 0.40 ENSDART00000062459
ENSDART00000180563
RNA binding motif protein 19
chr25_+_10909850 0.38 ENSDART00000186021

chr5_-_61609448 0.38 ENSDART00000133426
si:dkey-261j4.5
chr21_+_4313039 0.37 ENSDART00000141146
si:dkey-84o3.4
chr13_+_50151407 0.37 ENSDART00000031858
G protein-coupled receptor 137Ba
chr13_+_31583034 0.34 ENSDART00000111763
SIX homeobox 6a
chr14_+_23874062 0.33 ENSDART00000172149
SH3 domain containing ring finger 2
chr12_+_46404307 0.32 ENSDART00000185011

chr5_+_24882633 0.32 ENSDART00000111302
rhomboid domain containing 3
chr11_+_44804685 0.32 ENSDART00000163660
striatin, calmodulin binding protein
chr9_+_29548195 0.31 ENSDART00000176057
ring finger protein 17
chr22_-_30973791 0.31 ENSDART00000104728
ssu-2 homolog, tandem duplicate 2
chr19_-_1947403 0.30 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
zinc and ring finger 2a
chr15_-_23784600 0.29 ENSDART00000059354
RAD1 homolog (S. pombe)
chr5_-_66768121 0.29 ENSDART00000141095
im:7154036
chr1_+_54137089 0.29 ENSDART00000062945

chr22_-_23228669 0.28 ENSDART00000079536
NIMA-related kinase 7
chr13_+_2625150 0.27 ENSDART00000164177
phospholipid phosphatase 4
chr19_+_24891747 0.26 ENSDART00000132209
ENSDART00000193610
EYA transcriptional coactivator and phosphatase 3
chr5_-_4297459 0.26 ENSDART00000018895
serrate RNA effector molecule homolog (Arabidopsis)
chr19_-_3255725 0.26 ENSDART00000105165
immune-related, lectin-like receptor 1
chr13_-_40238813 0.26 ENSDART00000044963
lysyl oxidase-like 4
chr11_+_2687395 0.26 ENSDART00000082510
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr14_-_899170 0.26 ENSDART00000165211
ENSDART00000031992
regulator of G protein signaling 14a
chr21_+_27513859 0.26 ENSDART00000065420
phosphofurin acidic cluster sorting protein 1a
chr10_-_11385155 0.25 ENSDART00000064214
placenta-specific 8, tandem duplicate 1
chr23_-_31913231 0.25 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr23_-_24493768 0.25 ENSDART00000135559
ENSDART00000046933
sulfotransferase family 1, cytosolic sulfotransferase 5
chr3_-_31619463 0.24 ENSDART00000124559
minamoto
chr17_-_21162821 0.23 ENSDART00000157283
abhydrolase domain containing 12
chr14_-_3132188 0.22 ENSDART00000172259
si:zfos-1069f5.1
chr17_-_200316 0.22 ENSDART00000190561

chr23_-_32092443 0.22 ENSDART00000133688
LETM1 domain containing 1
chr10_+_16165533 0.20 ENSDART00000065045
proline-rich coiled-coil 1
chr3_-_34098731 0.20 ENSDART00000150999
immunoglobulin heavy variable 5-3
chr18_-_33979422 0.19 ENSDART00000136535
ENSDART00000167698
si:ch211-203b20.7
chr24_-_3783497 0.19 ENSDART00000158354
adenosine deaminase, RNA-specific, B2 (non-functional)
chr24_-_40860603 0.19 ENSDART00000188032

chr3_-_13461361 0.18 ENSDART00000080807
F-box and WD repeat domain containing 9
chr1_+_29183962 0.18 ENSDART00000113735
cysteinyl-tRNA synthetase 2, mitochondrial
chr5_+_66433287 0.18 ENSDART00000170757
kinetochore associated 1
chr15_-_28082310 0.18 ENSDART00000152620
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr3_-_17871846 0.18 ENSDART00000074478
ENSDART00000187941
NFKB inhibitor interacting Ras-like 2
chr7_-_24005268 0.18 ENSDART00000173608
si:dkey-183c6.9
chr23_-_39772067 0.18 ENSDART00000159519
ENSDART00000189046
im:6912630
chr25_-_24248000 0.18 ENSDART00000073527
SPT2 chromatin protein domain containing 1
chr23_+_43489182 0.17 ENSDART00000162062
zinc finger protein 341
chr10_+_40660772 0.17 ENSDART00000148007
trace amine associated receptor 19l
chr18_+_33264609 0.17 ENSDART00000050639
vomeronasal 2 receptor, a20
chr15_-_4094888 0.16 ENSDART00000166307
si:dkey-83h2.3
chr5_-_29512538 0.16 ENSDART00000098364
euchromatic histone-lysine N-methyltransferase 1a
chr10_-_5016997 0.15 ENSDART00000101414
heterogeneous nuclear ribonucleoprotein D
chr23_-_41965557 0.14 ENSDART00000144183
solute carrier family 1 (glutamate transporter), member 7b
chr11_+_25259058 0.13 ENSDART00000154109
tumor protein p53 inducible nuclear protein 2
chr17_-_25649079 0.12 ENSDART00000130955
protein phosphatase 1, catalytic subunit, beta isozyme
chr6_-_27891961 0.11 ENSDART00000155116
im:7152348
chr3_+_13848226 0.11 ENSDART00000184342
interleukin enhancer binding factor 3b
chr18_+_10884996 0.11 ENSDART00000147613
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr17_-_8656155 0.10 ENSDART00000148990
C-terminal binding protein 2a
chr23_-_31913069 0.09 ENSDART00000135526
mitochondrial fission regulator 2
chr17_+_5915875 0.09 ENSDART00000184179
fibronectin type III domain containing 4b
chr18_-_45761868 0.09 ENSDART00000025423
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr17_-_50054025 0.08 ENSDART00000190105

chr4_+_5506952 0.08 ENSDART00000032857
ENSDART00000160222
mitogen-activated protein kinase 11
chr14_-_7137808 0.08 ENSDART00000054803
tRNA phosphotransferase 1
chr8_+_37527575 0.08 ENSDART00000147239
odorant receptor, family H, subfamily 135, member 1
chr14_+_23520986 0.08 ENSDART00000170473
ENSDART00000175970
si:ch211-221f10.2
chr5_+_9246458 0.08 ENSDART00000081772
sushi domain containing 1
chr15_+_5339056 0.08 ENSDART00000174319

chr10_+_5954787 0.07 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr25_+_25085349 0.07 ENSDART00000192166
si:ch73-182e20.4
chr21_-_31013817 0.06 ENSDART00000065504
nuclear cap binding subunit 3
chr21_+_19062124 0.06 ENSDART00000134746
ribosomal protein L17
chr6_-_15641686 0.05 ENSDART00000135583
melanophilin a
chr18_-_33979693 0.05 ENSDART00000021215
si:ch211-203b20.7
chr14_-_32089117 0.05 ENSDART00000158014
si:ch211-69b22.5
chr12_-_2993095 0.05 ENSDART00000152316
si:dkey-202c14.3
chr5_-_2689753 0.04 ENSDART00000172699
guanine nucleotide binding protein (G protein), gamma 10
chr25_-_27729046 0.04 ENSDART00000131437
zgc:153935
chr22_+_31295791 0.03 ENSDART00000092447
glutamate receptor interacting protein 2b
chr13_-_50247689 0.03 ENSDART00000034541
G patch domain containing 11
chr7_-_26532089 0.03 ENSDART00000121698
SUMO1/sentrin/SMT3 specific peptidase 3b
chr15_+_2190229 0.02 ENSDART00000147710
arginine/serine-rich coiled-coil 1
chr10_-_41157135 0.02 ENSDART00000134851
AP2 associated kinase 1b
chr17_-_10122204 0.02 ENSDART00000160751

chr10_-_18463934 0.02 ENSDART00000133116
ENSDART00000113422
si:dkey-28o19.1
chr2_-_23778180 0.01 ENSDART00000136782
si:dkey-24c2.7
chr16_-_35394422 0.01 ENSDART00000180593
si:dkey-34d22.3
chr20_-_2134620 0.01 ENSDART00000064375
transmembrane protein 244
chr6_-_52348562 0.01 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eukaryotic translation initiation factor 6
chr1_+_11977426 0.01 ENSDART00000103399
tetraspanin 5b

Network of associatons between targets according to the STRING database.

First level regulatory network of msx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.6 GO:0043420 anthranilate metabolic process(GO:0043420)
0.6 3.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.6 1.8 GO:0019323 pentose catabolic process(GO:0019323)
0.6 1.7 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.5 2.2 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.5 1.6 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.3 3.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.3 5.3 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.3 1.5 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.3 2.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 0.8 GO:0015695 organic cation transport(GO:0015695)
0.3 1.0 GO:0010259 multicellular organism aging(GO:0010259)
0.3 2.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.3 2.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 1.4 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 0.7 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.2 1.2 GO:0032218 riboflavin transport(GO:0032218)
0.2 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.6 GO:0071451 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 1.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.4 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.6 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 3.6 GO:0030168 platelet activation(GO:0030168)
0.1 0.8 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 0.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 0.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 1.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.9 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 1.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 4.8 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 1.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.5 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 1.6 GO:0009636 response to toxic substance(GO:0009636)
0.1 1.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.9 GO:0045682 regulation of epidermis development(GO:0045682)
0.1 0.3 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.4 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0021795 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.0 0.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.6 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.3 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 1.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.0 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.4 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.6 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.2 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0001650 fibrillar center(GO:0001650)
0.1 1.1 GO:0071914 prominosome(GO:0071914)
0.1 0.6 GO:0030891 VCB complex(GO:0030891)
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.9 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 2.5 GO:0005811 lipid particle(GO:0005811)
0.0 5.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.9 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 2.1 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.5 1.6 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.5 2.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.5 3.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 1.5 GO:0051380 norepinephrine binding(GO:0051380)
0.3 3.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.2 1.1 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 1.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 1.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.8 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 4.6 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.9 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.8 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 1.1 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 1.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 3.9 GO:0005507 copper ion binding(GO:0005507)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 3.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.6 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.6 GO:0000049 tRNA binding(GO:0000049)
0.1 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 1.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 2.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 5.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 4.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 3.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 3.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 9.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.1 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis