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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for myca+mych

Z-value: 0.77

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Transcription factors associated with myca+mych

Gene Symbol Gene ID Gene Info
ENSDARG00000045695 MYC proto-oncogene, bHLH transcription factor a
ENSDARG00000077473 myelocytomatosis oncogene homolog

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycadr11_v1_chr24_+_10413484_10413484-0.471.6e-06Click!
mychdr11_v1_chr6_+_50451337_504513370.187.5e-02Click!

Activity profile of myca+mych motif

Sorted Z-values of myca+mych motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_39764995 9.54 ENSDART00000085277
phosphofructokinase, muscle b
chr21_+_11969603 6.67 ENSDART00000142247
ENSDART00000140652
motilin-like
chr20_-_53996193 6.61 ENSDART00000004756
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr12_-_33359654 6.32 ENSDART00000001907
solute carrier family 16 (monocarboxylate transporter), member 3
chr18_+_5490668 6.22 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr23_-_31555696 6.16 ENSDART00000053539
transcription factor 21
chr14_+_22076596 5.86 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr12_-_33359052 5.71 ENSDART00000135943
solute carrier family 16 (monocarboxylate transporter), member 3
chr7_-_73752955 5.63 ENSDART00000171254
ENSDART00000009888
calsequestrin 1b
chr6_-_21189295 4.88 ENSDART00000137136
obscurin-like 1a
chr12_+_30586599 4.73 ENSDART00000124920
ENSDART00000126984
nebulin-related anchoring protein
chr19_+_42983613 4.54 ENSDART00000033724
fatty acid binding protein 3, muscle and heart
chr18_+_8917766 4.54 ENSDART00000145226
si:ch211-233h19.2
chr14_+_23518110 4.49 ENSDART00000112930
si:ch211-221f10.2
chr21_-_20765338 4.48 ENSDART00000135940
growth hormone receptor b
chr5_-_3927692 4.45 ENSDART00000146840
ENSDART00000058346
complement component 1, q subcomponent binding protein
chr7_+_67467702 4.35 ENSDART00000168460
ENSDART00000170322
ribosomal protein L13
chr12_-_33357655 4.29 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr22_-_26834043 4.15 ENSDART00000087202
si:dkey-44g23.5
chr8_+_44783424 4.15 ENSDART00000025875
si:ch1073-459j12.1
chr16_+_25245857 4.06 ENSDART00000155220
kelch-like family member 38b
chr14_+_94603 4.05 ENSDART00000162480
minichromosome maintenance complex component 7
chr13_-_12021566 4.05 ENSDART00000125430
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr19_+_43119698 3.83 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eukaryotic translation elongation factor 1 alpha 1, like 1
chr16_+_16969060 3.70 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
ribosomal protein L18
chr16_+_16968682 3.66 ENSDART00000111074
si:ch211-120k19.1
chr18_-_11729 3.62 ENSDART00000159781
WAS protein homolog associated with actin, golgi membranes and microtubules
chr9_-_12888082 3.58 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
chr7_+_54605640 3.28 ENSDART00000168474
fibroblast growth factor 3
chr3_-_18805225 3.27 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr19_-_34117056 3.27 ENSDART00000158677
si:dkey-184p18.2
chr16_-_38629208 3.15 ENSDART00000126705
eukaryotic translation initiation factor 3, subunit E, a
chr3_+_24595922 2.98 ENSDART00000169405
si:dkey-68o6.5
chr21_+_26071874 2.98 ENSDART00000003001
ENSDART00000146573
ribosomal protein L23a
chr13_-_3516473 2.96 ENSDART00000146240
parkin RBR E3 ubiquitin protein ligase
chr20_+_54079341 2.85 ENSDART00000060444
ribosomal protein S29
chr6_-_41536323 2.80 ENSDART00000113157
HemK methyltransferase family member 1
chr10_-_39130839 2.76 ENSDART00000061274
ENSDART00000148648
ribosomal protein S25
chr24_+_34069675 2.75 ENSDART00000143995
si:ch211-190p8.2
chr22_-_607812 2.69 ENSDART00000145983
cyclin-dependent kinase inhibitor 1A
chr4_-_2945306 2.67 ENSDART00000128934
ENSDART00000019518
AE binding protein 2
chr7_-_23745984 2.65 ENSDART00000048050
zgc:92429
chr23_+_32499916 2.55 ENSDART00000134811
si:dkey-261h17.1
chr2_-_6182098 2.52 ENSDART00000156167
si:ch73-182a11.2
chr22_-_5323482 2.51 ENSDART00000145785
sphingosine-1-phosphate receptor 4
chr5_-_69314495 2.50 ENSDART00000182335
smoothelin b
chr20_+_25626479 2.47 ENSDART00000143883
phosphoribosyl pyrophosphate amidotransferase
chr19_-_46957968 2.47 ENSDART00000043713
angiopoietin 1
chr11_-_37995501 2.46 ENSDART00000192096
solute carrier family 41 (magnesium transporter), member 1
chr23_+_43870886 2.46 ENSDART00000102658
ENSDART00000149088
nuclear transcription factor, X-box binding-like 1
chr17_-_29771639 2.45 ENSDART00000086201
Usher syndrome 2A (autosomal recessive, mild)
chr18_-_11595567 2.44 ENSDART00000098565
calcium release activated channel regulator 2A
chr7_+_20344032 2.35 ENSDART00000144948
ENSDART00000138786
plac8 onzin related protein 1
chr18_+_14277003 2.31 ENSDART00000006628
zgc:173742
chr12_+_13091842 2.27 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr19_-_24555935 2.24 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr19_-_24555623 2.23 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr9_-_22281854 2.15 ENSDART00000146319
crystallin, gamma M2d3
chr2_-_42375275 2.14 ENSDART00000026339
GTP binding protein 4
chr17_+_8212477 2.13 ENSDART00000064665
solute carrier family 18, subfamily B, member 1
chr3_-_37148594 2.10 ENSDART00000140855
MLX, MAX dimerization protein
chr20_+_46660339 2.10 ENSDART00000016530
adenylate cyclase 3b
chr14_+_94946 2.05 ENSDART00000165766
ENSDART00000163778
minichromosome maintenance complex component 7
chr6_-_52348562 2.04 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eukaryotic translation initiation factor 6
chr16_-_42186093 2.03 ENSDART00000076030
fibrillarin
chr2_-_24369087 2.03 ENSDART00000081237
plasmalemma vesicle associated protein a
chr5_+_3927989 2.02 ENSDART00000030125
zinc finger, HIT-type containing 3
chr12_-_30359031 2.00 ENSDART00000192628
tudor domain containing 1
chr9_-_27396404 1.99 ENSDART00000136412
ENSDART00000101401
testis expressed 30
chr22_+_5120033 1.95 ENSDART00000169200
muscle-specific beta 1 integrin binding protein
chr9_+_56422311 1.94 ENSDART00000171958
G protein-coupled receptor 39
chr13_-_31370184 1.94 ENSDART00000034829
ribosomal RNA processing 12 homolog
chr21_+_6114709 1.93 ENSDART00000065858
folylpolyglutamate synthase
chr8_+_26059677 1.93 ENSDART00000009178
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr21_-_35853245 1.86 ENSDART00000172245
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr20_+_37294112 1.82 ENSDART00000076293
ENSDART00000140450
connexin 23
chr15_+_6661343 1.81 ENSDART00000160136
NOP53 ribosome biogenesis factor
chr14_+_16151636 1.78 ENSDART00000159352
polymerase (RNA) I polypeptide A
chr7_+_20030888 1.76 ENSDART00000192808
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr24_+_16905188 1.73 ENSDART00000066760
chaperonin containing TCP1, subunit 5 (epsilon)
chr15_-_17099560 1.72 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr7_-_58843193 1.71 ENSDART00000167231
mitochondrial ribosomal protein L15
chr13_-_35907768 1.70 ENSDART00000147522
MYCL proto-oncogene, bHLH transcription factor a
chr21_-_30082414 1.68 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr17_+_2162916 1.67 ENSDART00000103775
p21 protein (Cdc42/Rac)-activated kinase 6a
chr5_-_32338866 1.66 ENSDART00000017956
ENSDART00000047670
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr12_+_48395693 1.65 ENSDART00000180362
stearoyl-CoA desaturase (delta-9-desaturase)
chr20_-_54259780 1.62 ENSDART00000172631
FK506 binding protein 3
chr9_+_56422517 1.61 ENSDART00000168620
G protein-coupled receptor 39
chr2_+_49860722 1.60 ENSDART00000144060
ribosomal protein L37
chr3_+_1150348 1.58 ENSDART00000148524
nucleolar protein 12
chr10_+_22034477 1.57 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
nucleophosmin 1a
chr13_-_35892051 1.50 ENSDART00000145884
transforming, acidic coiled-coil containing protein 3
chr6_-_58975010 1.50 ENSDART00000144911
ENSDART00000144514
methionyl-tRNA synthetase
chr17_-_45370200 1.48 ENSDART00000186208
zinc finger protein 106a
chr24_-_42090635 1.43 ENSDART00000166413
signal sequence receptor, alpha
chr18_-_20608025 1.43 ENSDART00000090156
ENSDART00000151980
BCL2 like 13
chr13_+_31402067 1.41 ENSDART00000019202
tudor domain containing 9
chr22_+_17261801 1.38 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr21_+_34119759 1.38 ENSDART00000024750
ENSDART00000128242
high mobility group box 3b
chr6_-_52796212 1.37 ENSDART00000154133
recombination signal binding protein for immunoglobulin kappa J region-like
chr23_-_38160024 1.37 ENSDART00000087112
prefoldin subunit 4
chr1_-_55750208 1.35 ENSDART00000142244
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr15_-_36533322 1.35 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
chr11_+_6009984 1.32 ENSDART00000185680
GTP binding protein 3, mitochondrial
chr9_-_30259295 1.32 ENSDART00000139106
si:dkey-100n23.5
chr16_+_40954481 1.29 ENSDART00000058587
glycogen synthase kinase binding protein
chr22_-_30430276 1.29 ENSDART00000123840

chr20_+_25445826 1.28 ENSDART00000012581
phosphoribosylformylglycinamidine synthase
chr5_-_16425781 1.28 ENSDART00000185624
ENSDART00000180617
solute carrier family 39 (zinc transporter), member 14
chr9_+_38158570 1.27 ENSDART00000059549
ENSDART00000133060
nucleolar protein interacting with the FHA domain of MKI67
chr7_+_30779761 1.26 ENSDART00000066806
ENSDART00000173671
methylmalonyl CoA epimerase
chr18_+_33386372 1.26 ENSDART00000141838
vomeronasal 2 receptor, h12
chr13_+_30912385 1.26 ENSDART00000182642
dorsal root ganglia homeobox
chr14_+_5385855 1.24 ENSDART00000031508
ladybird homeobox 2
chr20_+_6543674 1.24 ENSDART00000134204
tensin 3, tandem duplicate 1
chr11_+_3959495 1.22 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr13_-_9061944 1.20 ENSDART00000164186
ENSDART00000102051
si:dkey-112g5.12
chr9_-_11587070 1.19 ENSDART00000030995
uridine monophosphate synthetase
chr6_-_39080630 1.19 ENSDART00000021520
ENSDART00000128308
eukaryotic translation initiation factor 4Bb
chr19_-_32804535 1.18 ENSDART00000175613
ENSDART00000052098
5'-nucleotidase, cytosolic IAa
chr22_+_6293563 1.18 ENSDART00000063416
ribonuclease like 2
chr6_-_54078623 1.17 ENSDART00000154076
hyaluronoglucosaminidase 1
chr7_+_17973269 1.16 ENSDART00000079969
potassium channel, subfamily K, member 7
chr17_+_654759 1.16 ENSDART00000193703

chr10_+_575929 1.16 ENSDART00000129856
SMAD family member 4a
chr2_+_30547018 1.15 ENSDART00000193747
ankyrin repeat domain 33Bb
chr5_-_8765428 1.15 ENSDART00000167793
MYB binding protein (P160) 1a
chr23_+_36122058 1.14 ENSDART00000184448
homeobox C3a
chr22_+_5118361 1.14 ENSDART00000168371
ENSDART00000170222
ENSDART00000158846
muscle-specific beta 1 integrin binding protein
chr18_-_5850683 1.13 ENSDART00000082087
NIP7, nucleolar pre-rRNA processing protein
chr22_-_12745589 1.13 ENSDART00000136841
phospholipase C, delta 4a
chr5_+_68807170 1.13 ENSDART00000017849
hairy and enhancer of split related-7
chr22_-_28777557 1.12 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
chr20_+_25625872 1.12 ENSDART00000078385
phosphoribosyl pyrophosphate amidotransferase
chr21_+_17768174 1.11 ENSDART00000141380
retinoid X receptor, alpha a
chr16_-_8520474 1.11 ENSDART00000137365
growth factor receptor-bound protein 10b
chr13_-_9295890 1.10 ENSDART00000110680
si:dkey-33c12.12
chr8_+_25295160 1.10 ENSDART00000049793
glutathione S-transferase mu, tandem duplicate 1
chr4_+_2620751 1.08 ENSDART00000013924
G protein-coupled receptor 22a
chr8_+_15277874 1.08 ENSDART00000146965
deoxynucleotidyltransferase, terminal, interacting protein 2
chr17_-_19534474 1.07 ENSDART00000192469
cytochrome P450, family 26, subfamily C, polypeptide 1
chr11_+_6010177 1.07 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
GTP binding protein 3, mitochondrial
chr1_-_19648227 1.07 ENSDART00000054574
polymerase (RNA) I polypeptide E
chr7_-_38340674 1.07 ENSDART00000075782
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr12_+_27117609 1.07 ENSDART00000076154
homeobox B8b
chr19_+_31061718 1.07 ENSDART00000145971
sclerostin domain containing 1b
chr24_+_36317544 1.06 ENSDART00000048640
ENSDART00000156096
pseudouridylate synthase 3
chr12_-_20350629 1.05 ENSDART00000066384
hemoglobin beta embryonic-2
chr5_-_54195084 1.05 ENSDART00000171811
G protein-coupled receptor kinase 1 b
chr20_-_40725142 1.02 ENSDART00000181279
connexin 32.2
chr21_-_11327830 1.02 ENSDART00000122331
rhotekin 2b
chr21_-_22122312 1.02 ENSDART00000101726
solute carrier family 35, member F2
chr9_+_12887491 1.01 ENSDART00000102386
si:ch211-167j6.4
chr2_-_48171112 1.01 ENSDART00000156258
phosphofructokinase, platelet b
chr13_+_48359573 0.98 ENSDART00000161959
ENSDART00000165311
mutS homolog 6 (E. coli)
chr17_+_36627099 0.97 ENSDART00000154104
interphotoreceptor matrix proteoglycan 1b
chr3_+_28939759 0.96 ENSDART00000141904
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr16_+_41974438 0.96 ENSDART00000102771
si:ch211-225p5.8
chr3_+_51660158 0.96 ENSDART00000155512
ENSDART00000171764
charged multivesicular body protein 6a
chr20_-_26531850 0.95 ENSDART00000183317
ENSDART00000131994
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr14_+_16151368 0.95 ENSDART00000160973
polymerase (RNA) I polypeptide A
chr17_+_51682429 0.94 ENSDART00000004379
nucleolar protein 10
chr14_+_5861435 0.93 ENSDART00000041279
ENSDART00000147341
tubulin, beta 4B class IVb
chr25_-_14424406 0.93 ENSDART00000073609
protein arginine methyltransferase 7
chr3_+_58379450 0.92 ENSDART00000155759
short chain dehydrogenase/reductase family 42E, member 2
chr3_-_25377163 0.92 ENSDART00000055490
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr3_-_41791178 0.92 ENSDART00000049687
galectin-related inter-fiber protein
chr1_-_54972170 0.91 ENSDART00000150548
ENSDART00000038330
KH-type splicing regulatory protein
chr19_+_21820144 0.91 ENSDART00000181996

chr23_+_38159715 0.90 ENSDART00000137969
zgc:112994
chr16_-_54455573 0.90 ENSDART00000075275
pyruvate kinase L/R
chr11_+_25485774 0.89 ENSDART00000026249
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr25_+_3231812 0.88 ENSDART00000163647
methionyl aminopeptidase 2b
chr21_-_17603182 0.88 ENSDART00000020048
ENSDART00000177270
gelsolin a
chr10_+_29849977 0.87 ENSDART00000180242
heat shock protein 8
chr21_-_30408775 0.85 ENSDART00000101037
NHP2 ribonucleoprotein homolog (yeast)
chr4_-_38033800 0.84 ENSDART00000159662
si:dkeyp-82b4.4
chr6_+_54078703 0.84 ENSDART00000110845
fragile histidine triad gene
chr25_+_245438 0.82 ENSDART00000004689
zgc:92481
chr10_+_35002786 0.82 ENSDART00000099552
exosome component 8
chr1_+_31674297 0.81 ENSDART00000044214
WW domain binding protein 1-like b
chr10_+_29850330 0.81 ENSDART00000168898
heat shock protein 8
chr4_+_3455665 0.81 ENSDART00000058277
zinc finger protein 800b
chr13_-_4223955 0.80 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr5_-_33935396 0.79 ENSDART00000133578
si:dkeyp-72a4.1
chr14_+_8638353 0.79 ENSDART00000163240
si:dkeyp-115e12.6
chr3_+_23029934 0.78 ENSDART00000110343
N-acetylglutamate synthase
chr7_-_12596727 0.78 ENSDART00000186413
ADAMTS-like 3
chr11_-_44194132 0.77 ENSDART00000182954
ENSDART00000111271

chr25_-_36248053 0.77 ENSDART00000134928
nuclear factor of activated T cells 3b
chr23_-_35547613 0.77 ENSDART00000122387
ALK and LTK ligand 2a
chr7_-_30779575 0.76 ENSDART00000004782
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr10_+_428269 0.76 ENSDART00000140715
zinc finger, DHHC-type containing 8a
chr14_+_14836468 0.76 ENSDART00000166728
si:dkey-102m7.3
chr4_+_18824959 0.75 ENSDART00000146141
ENSDART00000040424
solute carrier family 26 (anion exchanger), member 3
chr1_-_17570013 0.75 ENSDART00000146946
acyl-CoA synthetase long chain family member 1a
chr2_-_32386598 0.74 ENSDART00000145575
upstream binding transcription factor, like
chr8_-_13678415 0.74 ENSDART00000134153
ENSDART00000143331
si:dkey-258f14.3
chr5_-_16475374 0.74 ENSDART00000134274
ENSDART00000136004
piwi-like RNA-mediated gene silencing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of myca+mych

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
1.9 5.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.7 6.6 GO:0045429 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
1.1 4.4 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
1.1 3.3 GO:0021985 neurohypophysis development(GO:0021985)
1.0 10.5 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.8 4.7 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.7 2.0 GO:1902626 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.6 6.5 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.6 2.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.6 1.7 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.6 6.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.5 1.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4 1.3 GO:0033212 iron assimilation(GO:0033212)
0.4 1.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 4.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.4 1.1 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.4 1.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.4 1.1 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.3 4.5 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.3 1.0 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 1.2 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.3 3.0 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.3 3.8 GO:0009303 rRNA transcription(GO:0009303)
0.3 2.0 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.3 2.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 0.9 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.3 1.7 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.3 0.8 GO:0071042 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.3 0.8 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.3 1.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.3 1.0 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.2 1.2 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 1.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 2.4 GO:0072088 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.2 6.2 GO:0070831 basement membrane assembly(GO:0070831)
0.2 0.9 GO:0070084 protein initiator methionine removal(GO:0070084)
0.2 4.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 1.7 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.2 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 2.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 0.8 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 1.7 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 2.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.2 1.9 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.2 1.1 GO:0055014 outflow tract morphogenesis(GO:0003151) atrial cardiac muscle cell development(GO:0055014)
0.2 1.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 0.7 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.2 2.7 GO:0010165 response to X-ray(GO:0010165)
0.2 5.9 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.2 14.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.2 4.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.8 GO:0015961 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.1 1.0 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.8 GO:0070378 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 3.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 1.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.3 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.3 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 1.0 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.2 GO:0009265 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) 2'-deoxyribonucleotide biosynthetic process(GO:0009265) deoxyribose phosphate biosynthetic process(GO:0046385)
0.1 1.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 2.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.4 GO:0006265 DNA topological change(GO:0006265)
0.1 1.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 4.9 GO:0010842 retina layer formation(GO:0010842)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.3 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 4.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 1.3 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.1 1.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 1.6 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.1 0.2 GO:0071028 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.1 0.4 GO:0061339 establishment of apical/basal cell polarity(GO:0035089) establishment of epithelial cell apical/basal polarity(GO:0045198) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 5.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 3.9 GO:0006414 translational elongation(GO:0006414)
0.1 0.7 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 0.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 1.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 1.1 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.1 1.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.8 GO:0051310 metaphase plate congression(GO:0051310)
0.1 1.1 GO:0015671 oxygen transport(GO:0015671)
0.1 0.5 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 1.1 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 1.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.1 GO:0042255 ribosome assembly(GO:0042255)
0.0 1.0 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 1.1 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 1.1 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.6 GO:0009651 response to salt stress(GO:0009651)
0.0 1.2 GO:0048264 determination of ventral identity(GO:0048264)
0.0 2.1 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 1.7 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 1.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 2.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.9 GO:0051014 actin filament severing(GO:0051014)
0.0 0.9 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 11.1 GO:0006412 translation(GO:0006412)
0.0 2.8 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 1.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.3 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 0.2 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.6 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.0 3.9 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 1.5 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.5 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 2.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 3.3 GO:0030041 actin filament polymerization(GO:0030041)
0.0 0.5 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.7 GO:0006457 protein folding(GO:0006457)
0.0 0.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.2 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.4 GO:0043588 skin development(GO:0043588)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0070195 growth hormone receptor complex(GO:0070195)
1.0 10.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.8 5.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.6 3.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.5 4.1 GO:0071546 pi-body(GO:0071546)
0.4 6.6 GO:0043209 myelin sheath(GO:0043209)
0.3 6.1 GO:0042555 MCM complex(GO:0042555)
0.3 1.0 GO:0032301 MutSalpha complex(GO:0032301)
0.3 4.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 3.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 1.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 0.8 GO:0034457 Mpp10 complex(GO:0034457)
0.2 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 0.9 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 0.6 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2 1.0 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 2.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 11.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.4 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 4.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 3.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.4 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 5.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.2 GO:0070938 contractile ring(GO:0070938)
0.1 2.6 GO:0031941 filamentous actin(GO:0031941)
0.1 1.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.3 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.4 GO:0043186 P granule(GO:0043186)
0.1 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 11.4 GO:0005730 nucleolus(GO:0005730)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 1.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.0 1.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 3.3 GO:0005604 basement membrane(GO:0005604)
0.0 4.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.7 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0014704 intercalated disc(GO:0014704)
0.0 2.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 16.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
1.3 9.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
1.2 6.1 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
1.1 4.5 GO:0004903 growth hormone receptor activity(GO:0004903)
1.0 10.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.9 6.2 GO:0070888 E-box binding(GO:0070888)
0.8 3.3 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.5 4.4 GO:0008494 translation activator activity(GO:0008494)
0.4 1.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.4 1.6 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.4 1.8 GO:0008097 5S rRNA binding(GO:0008097)
0.3 2.7 GO:0034584 piRNA binding(GO:0034584)
0.3 2.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 2.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.0 GO:0032143 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.3 2.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 0.9 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 0.9 GO:0048030 disaccharide binding(GO:0048030)
0.3 0.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 0.8 GO:0034618 arginine binding(GO:0034618)
0.2 0.7 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.2 1.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 1.0 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.2 1.2 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.2 4.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.2 1.5 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 5.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 6.1 GO:0019843 rRNA binding(GO:0019843)
0.1 1.1 GO:0036122 BMP binding(GO:0036122)
0.1 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.5 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.1 0.8 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 12.3 GO:0051082 unfolded protein binding(GO:0051082)
0.1 2.0 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 1.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.4 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 4.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.0 GO:0016936 galactoside binding(GO:0016936)
0.1 2.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.8 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 15.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 1.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.1 GO:0031720 haptoglobin binding(GO:0031720)
0.1 3.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.5 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 1.3 GO:0030552 cAMP binding(GO:0030552)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.4 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.7 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.2 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 3.6 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 2.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 3.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.1 GO:0051020 GTPase binding(GO:0051020)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 4.5 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 6.5 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 4.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 1.9 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 7.2 GO:0005525 GTP binding(GO:0005525)
0.0 2.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 4.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 2.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 6.1 PID ATR PATHWAY ATR signaling pathway
0.1 1.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 1.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 16.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 6.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 6.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 3.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.3 4.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 1.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 1.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 18.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 3.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.9 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 5.0 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 2.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes