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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for mycn

Z-value: 1.16

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Transcription factors associated with mycn

Gene Symbol Gene ID Gene Info
ENSDARG00000006837 MYCN proto-oncogene, bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycndr11_v1_chr20_+_33294428_33294428-0.331.4e-03Click!

Activity profile of mycn motif

Sorted Z-values of mycn motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_6293563 14.78 ENSDART00000063416
ribonuclease like 2
chr24_-_2829049 14.75 ENSDART00000164913
si:ch211-152c8.5
chr12_-_6159545 12.12 ENSDART00000152487
RAMP-like triterpene glycoside receptor
chr15_-_21877726 9.86 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr9_+_56422311 9.18 ENSDART00000171958
G protein-coupled receptor 39
chr5_-_20123002 8.50 ENSDART00000026516
peroxisomal membrane protein 2
chr16_-_21489514 8.11 ENSDART00000149525
ENSDART00000148517
ENSDART00000146914
ENSDART00000186493
ENSDART00000193081
ENSDART00000186017
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr7_+_6652967 8.10 ENSDART00000102681
purine nucleoside phosphorylase 5a
chr14_-_30387894 7.79 ENSDART00000176136
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_+_26396552 7.64 ENSDART00000087151
aminomethyltransferase
chr4_-_16824231 7.56 ENSDART00000014007
glycogen synthase 2
chr13_-_12021566 7.44 ENSDART00000125430
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr7_+_20031202 7.21 ENSDART00000052904
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr17_+_19499157 7.05 ENSDART00000077804
solute carrier family 22, member 15
chr4_-_16824556 7.03 ENSDART00000165289
ENSDART00000185839
glycogen synthase 2
chr11_-_37995501 6.83 ENSDART00000192096
solute carrier family 41 (magnesium transporter), member 1
chr3_-_36764865 6.68 ENSDART00000173186
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr6_+_29305190 6.31 ENSDART00000078647
si:ch211-201h21.5
chr19_-_24555935 6.28 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr2_+_18988407 6.23 ENSDART00000170216
glutamate-ammonia ligase (glutamine synthase) a
chr11_-_5865744 5.78 ENSDART00000104360
guanidinoacetate N-methyltransferase
chr19_-_24555623 5.78 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr21_+_6114709 5.45 ENSDART00000065858
folylpolyglutamate synthase
chr4_-_17391091 5.41 ENSDART00000056002
tyrosine hydroxylase 2
chr6_-_8498908 5.37 ENSDART00000149222
peptidoglycan recognition protein 2
chr3_+_3810919 5.26 ENSDART00000056035

chr21_+_6780340 5.02 ENSDART00000139493
ENSDART00000140478
olfactomedin 1b
chr11_+_44503774 4.80 ENSDART00000169295
endoplasmic reticulum oxidoreductase beta
chr7_-_60831082 4.79 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr13_-_25199260 4.73 ENSDART00000057605
adenosine kinase a
chr10_+_29770120 4.66 ENSDART00000100032
ENSDART00000193205
hypoxia up-regulated 1
chr19_-_8940068 4.65 ENSDART00000043507
circadian associated repressor of transcription a
chr9_-_10003711 4.56 ENSDART00000124516
ENSDART00000102448
UDP glucuronosyltransferase 1 family a, b
chr23_+_17522867 4.54 ENSDART00000002714
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr20_-_22798794 4.39 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr20_+_46311707 4.39 ENSDART00000184743
feline leukemia virus subgroup C cellular receptor family, member 2b
chr2_-_17393971 4.38 ENSDART00000100201
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr9_+_38158570 4.28 ENSDART00000059549
ENSDART00000133060
nucleolar protein interacting with the FHA domain of MKI67
chr21_-_19919918 4.27 ENSDART00000137307
ENSDART00000142523
ENSDART00000065670
protein phosphatase 1, regulatory subunit 3B
chr7_-_30779575 4.25 ENSDART00000004782
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr21_-_22122312 4.23 ENSDART00000101726
solute carrier family 35, member F2
chr6_-_59563597 4.16 ENSDART00000166311
inhibin beta E subunit
chr7_-_55539738 4.06 ENSDART00000168721
ENSDART00000013796
ENSDART00000148514
adenine phosphoribosyltransferase
chr23_+_32101361 4.06 ENSDART00000138849
zgc:56699
chr6_-_29377092 4.03 ENSDART00000078665
transmembrane protein 131
chr13_-_4992395 3.90 ENSDART00000102651
nucleolar and coiled-body phosphoprotein 1
chr5_+_57328535 3.89 ENSDART00000149646
solute carrier family 31 (copper transporter), member 1
chr1_+_29664336 3.83 ENSDART00000088290
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b
chr21_+_6114305 3.78 ENSDART00000141607
folylpolyglutamate synthase
chr14_-_25452503 3.65 ENSDART00000148652
solute carrier family 26 (anion exchanger), member 2
chr10_-_26744131 3.62 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr16_+_13860299 3.61 ENSDART00000121998
glutamate-rich WD repeat containing 1
chr12_+_33975065 3.60 ENSDART00000036649
sideroflexin 2
chr3_+_24595922 3.54 ENSDART00000169405
si:dkey-68o6.5
chr11_+_11974708 3.52 ENSDART00000125060
zgc:64002
chr18_-_40684756 3.51 ENSDART00000113799
ENSDART00000139042
si:ch211-132b12.7
chr9_-_12652984 3.51 ENSDART00000052256
small ubiquitin-like modifier 3b
chr5_-_8765428 3.51 ENSDART00000167793
MYB binding protein (P160) 1a
chr16_-_42186093 3.48 ENSDART00000076030
fibrillarin
chr10_+_22034477 3.42 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
nucleophosmin 1a
chr5_-_43859148 3.41 ENSDART00000162746
ENSDART00000128763
si:ch211-204c21.1
chr14_+_14836468 3.38 ENSDART00000166728
si:dkey-102m7.3
chr12_-_22238004 3.37 ENSDART00000038310
ORMDL sphingolipid biosynthesis regulator 3
chr17_-_49407091 3.34 ENSDART00000021950
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr7_-_65492048 3.33 ENSDART00000162381
dickkopf WNT signaling pathway inhibitor 3a
chr13_+_15701849 3.32 ENSDART00000003517
tRNA methyltransferase 61A
chr23_+_37086159 3.32 ENSDART00000074407
ceramide-1-phosphate transfer protein
chr1_+_5485799 3.29 ENSDART00000022307
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr23_-_36441693 3.28 ENSDART00000024354
cysteine sulfinic acid decarboxylase
chr22_-_20695237 3.24 ENSDART00000112722
oogenesis-related gene
chr24_-_38644937 3.20 ENSDART00000170194
solute carrier family 6, member 16b
chr20_-_147574 3.15 ENSDART00000104762
ENSDART00000131635
solute carrier family 16 (aromatic amino acid transporter), member 10
chr20_-_38827623 3.13 ENSDART00000153310
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr18_+_27489595 3.09 ENSDART00000182018
tumor protein p53 inducible protein 11b
chr6_-_39653972 3.04 ENSDART00000155859
La ribonucleoprotein domain family, member 4Ab
chr2_+_23613040 3.03 ENSDART00000026694
ribonuclease P/MRP 40 subunit
chr1_-_18803919 3.02 ENSDART00000020970
phosphoglucomutase 2
chr18_+_14277003 3.01 ENSDART00000006628
zgc:173742
chr25_+_19095231 3.00 ENSDART00000154066
interferon stimulated exonuclease gene
chr21_-_14832369 2.99 ENSDART00000144859
pseudouridylate synthase 1
chr2_-_32512648 2.95 ENSDART00000170674
ATP-binding cassette, sub-family F (GCN20), member 2a
chr9_+_907459 2.92 ENSDART00000034850
ENSDART00000144114
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr7_+_20030888 2.90 ENSDART00000192808
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr14_+_22447662 2.87 ENSDART00000161776
sosondowah ankyrin repeat domain family member Ab
chr19_-_30800004 2.85 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
tRNA isopentenyltransferase 1
chr20_-_45772306 2.81 ENSDART00000062092
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr10_+_5689510 2.77 ENSDART00000183217
ENSDART00000172632
peptidylglycine alpha-amidating monooxygenase
chr8_-_13678415 2.76 ENSDART00000134153
ENSDART00000143331
si:dkey-258f14.3
chr5_-_63644938 2.76 ENSDART00000050865
surfeit gene 4, like
chr9_-_11587070 2.74 ENSDART00000030995
uridine monophosphate synthetase
chr3_+_48561112 2.73 ENSDART00000159682
solute carrier family 16 (monocarboxylate transporter), member 5b
chr21_-_30408775 2.71 ENSDART00000101037
NHP2 ribonucleoprotein homolog (yeast)
chr23_+_2906031 2.70 ENSDART00000109304
c23h20orf24 homolog (H. sapiens)
chr4_-_16001118 2.70 ENSDART00000041070
ENSDART00000125389
mesoderm specific transcript
chr6_+_21001264 2.70 ENSDART00000044519
ENSDART00000151278
connexin 44.2
chr1_+_12195700 2.68 ENSDART00000040307
tudor domain containing 7 a
chr13_+_13930263 2.65 ENSDART00000079154
ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
chr17_-_32636533 2.60 ENSDART00000109927
cell growth regulator with EF-hand domain 1
chr6_+_3717613 2.60 ENSDART00000184330
Sjogren syndrome antigen B (autoantigen La)
chr16_-_45178430 2.59 ENSDART00000165186
si:dkey-33i11.9
chr16_-_45327616 2.57 ENSDART00000158733
si:dkey-33i11.1
chr1_+_56180416 2.55 ENSDART00000089358
crumbs homolog 3b
chr3_-_40955780 2.55 ENSDART00000130130
cytochrome P450, family 3, subfamily c, polypeptide 3
chr2_-_39036604 2.55 ENSDART00000129963
retinol binding protein 1b, cellular
chr9_-_11676491 2.55 ENSDART00000022358
zinc finger CCCH-type containing 15
chr20_-_23439011 2.53 ENSDART00000022887
solute carrier family 10, member 4
chr10_+_21434649 2.49 ENSDART00000193938
ENSDART00000064558
eukaryotic translation termination factor 1b
chr5_-_55914268 2.47 ENSDART00000014049
WD repeat domain 36
chr6_-_16456093 2.46 ENSDART00000083305
ENSDART00000181640
solute carrier family 19 (thiamine transporter), member 2
chr5_-_67993086 2.45 ENSDART00000049331
general transcription factor IIIAa
chr24_+_34069675 2.44 ENSDART00000143995
si:ch211-190p8.2
chr22_+_15343953 2.42 ENSDART00000045682
ribosomal RNA processing 36
chr23_-_43718067 2.36 ENSDART00000015777
ATP-binding cassette, sub-family E (OABP), member 1
chr14_-_46675850 2.35 ENSDART00000113285
transmembrane anterior posterior transformation 1a
chr5_+_62356304 2.34 ENSDART00000148381
aspartoacylase
chr14_-_25985698 2.29 ENSDART00000172909
ENSDART00000123053
antioxidant 1 copper chaperone
chr25_+_16945348 2.29 ENSDART00000016591
fibroblast growth factor 6a
chr17_+_8211992 2.25 ENSDART00000133301
solute carrier family 18, subfamily B, member 1
chr10_-_22831611 2.19 ENSDART00000160115
period circadian clock 1a
chr20_-_33705044 2.18 ENSDART00000166573
rho-associated, coiled-coil containing protein kinase 2b
chr3_-_48612078 2.18 ENSDART00000169923
nudE neurodevelopment protein 1-like 1b
chr20_+_25625872 2.16 ENSDART00000078385
phosphoribosyl pyrophosphate amidotransferase
chr16_+_40560622 2.15 ENSDART00000038294
tumor protein p53 inducible nuclear protein 1
chr13_-_30161684 2.14 ENSDART00000040409
pyrophosphatase (inorganic) 1b
chr17_+_17764979 2.13 ENSDART00000105013
alkB homolog 1, histone H2A dioxygenase
chr1_-_6494384 2.13 ENSDART00000109356
Kruppel-like factor 7a
chr5_-_54714789 2.13 ENSDART00000063357
cyclin B1
chr7_-_39751540 2.10 ENSDART00000016803
GrpE-like 1, mitochondrial
chr2_+_25839193 2.08 ENSDART00000078634
eukaryotic translation initiation factor 5A2
chr18_+_14645568 2.08 ENSDART00000138995
ENSDART00000147351
VPS9 domain containing 1
chr22_+_24220937 2.08 ENSDART00000165380
ubiquitin carboxyl-terminal hydrolase L5
chr19_+_10831362 2.06 ENSDART00000053325
translocase of outer mitochondrial membrane 40 homolog, like
chr24_+_21514283 2.05 ENSDART00000007066
cyclin-dependent kinase 8
chr11_+_3959495 2.04 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr20_-_20312789 2.03 ENSDART00000114779
si:ch211-212g7.6
chr19_-_22346582 2.03 ENSDART00000045675
ENSDART00000169065
solute carrier family 52 (riboflavin transporter), member 2
zgc:109744
chr9_-_12888082 2.02 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
chr1_-_54706039 2.01 ENSDART00000083633
exosome component 1
chr5_-_54714525 1.97 ENSDART00000150138
ENSDART00000150070
cyclin B1
chr9_-_31278048 1.93 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr20_+_25445826 1.93 ENSDART00000012581
phosphoribosylformylglycinamidine synthase
chr3_-_32362872 1.92 ENSDART00000035545
ENSDART00000012630
protein arginine methyltransferase 1
chr2_-_9748039 1.91 ENSDART00000134870
si:ch1073-170o4.1
chr19_+_42983613 1.91 ENSDART00000033724
fatty acid binding protein 3, muscle and heart
chr12_-_9700605 1.90 ENSDART00000161063
HEAT repeat containing 1
chr6_-_29305132 1.90 ENSDART00000132456
basic, immunoglobulin-like variable motif containing
chr13_-_4223955 1.90 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr19_+_20201254 1.88 ENSDART00000010140
insulin-like growth factor 2 mRNA binding protein 3
chr7_+_38717624 1.88 ENSDART00000132522
synaptotagmin XIII
chr16_-_42175617 1.87 ENSDART00000084715
alkB homolog 8, tRNA methyltransferase
chr2_-_38363017 1.87 ENSDART00000088026
protein arginine methyltransferase 5
chr9_+_42066030 1.86 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr9_-_27391908 1.86 ENSDART00000135221
nucleolus and neural progenitor protein
chr10_-_35002731 1.85 ENSDART00000131279
asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase)
chr14_+_16151636 1.85 ENSDART00000159352
polymerase (RNA) I polypeptide A
chr13_-_40316367 1.84 ENSDART00000009343
pyridine nucleotide-disulphide oxidoreductase domain 2
chr4_-_18436899 1.84 ENSDART00000141671
suppressor of cytokine signaling 2
chr8_-_38317914 1.84 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr17_+_24318753 1.79 ENSDART00000064083
orthodenticle homeobox 1
chr22_-_28777557 1.77 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
chr13_-_37519774 1.77 ENSDART00000141420
ENSDART00000185478
sphingosine-1-phosphate phosphatase 1
chr14_+_16287968 1.76 ENSDART00000106593
pre-mRNA processing factor 19
chr1_+_44390470 1.75 ENSDART00000100321
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr14_-_8940499 1.73 ENSDART00000129030
zgc:153681
chr1_-_19648227 1.72 ENSDART00000054574
polymerase (RNA) I polypeptide E
chr11_-_44543082 1.71 ENSDART00000099568
G protein-coupled receptor 137Bb
chr16_-_33650578 1.71 ENSDART00000058460
UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
chr7_+_7630409 1.70 ENSDART00000172934
chloride channel 3
chr7_+_41322407 1.70 ENSDART00000114076
ENSDART00000139093
DPH2 homolog (S. cerevisiae)
chr20_-_39735952 1.70 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tumor protein D52-like 1
chr6_-_39167732 1.69 ENSDART00000153626
apolipoprotein F
chr7_+_55292959 1.69 ENSDART00000147539
ENSDART00000073555
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr19_+_20201593 1.68 ENSDART00000163026
insulin-like growth factor 2 mRNA binding protein 3
chr13_-_31370184 1.67 ENSDART00000034829
ribosomal RNA processing 12 homolog
chr18_-_5850683 1.67 ENSDART00000082087
NIP7, nucleolar pre-rRNA processing protein
chr21_-_20765338 1.66 ENSDART00000135940
growth hormone receptor b
chr22_+_17261801 1.65 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr4_+_18963822 1.63 ENSDART00000066975
ENSDART00000066973
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr25_-_14424406 1.61 ENSDART00000073609
protein arginine methyltransferase 7
chr4_-_6809323 1.61 ENSDART00000099467
interferon-related developmental regulator 1
chr10_+_32066537 1.60 ENSDART00000124166
si:dkey-250d21.1
chr13_-_4664403 1.60 ENSDART00000023803
ENSDART00000177957
C1D nuclear receptor corepressor
chr15_+_6652396 1.60 ENSDART00000192813
ENSDART00000157678
NOP53 ribosome biogenesis factor
chr17_+_51682429 1.59 ENSDART00000004379
nucleolar protein 10
chr8_+_35964482 1.58 ENSDART00000129357
ENSDART00000154953
glycosyltransferase 1 domain containing 1
chr18_-_38244871 1.57 ENSDART00000076399
N-acetyltransferase 10
chr21_+_34119759 1.56 ENSDART00000024750
ENSDART00000128242
high mobility group box 3b
chr12_+_10448226 1.55 ENSDART00000152824
crystallin, mu
chr3_+_19665319 1.53 ENSDART00000007857
ENSDART00000193509
methyltransferase like 2A
chr22_-_36690742 1.53 ENSDART00000017188
ENSDART00000124698
nucleolin
chr21_-_4539899 1.53 ENSDART00000112460
dolichol kinase
chr15_-_17099560 1.52 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr11_-_26375575 1.52 ENSDART00000079255
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr4_+_5180650 1.50 ENSDART00000067390
fibroblast growth factor 6b
chr23_+_32011768 1.49 ENSDART00000053509
pleiomorphic adenoma gene X
chr7_+_59169081 1.49 ENSDART00000167980
oligosaccharyltransferase complex subunit
chr14_+_16151368 1.47 ENSDART00000160973
polymerase (RNA) I polypeptide A
chr24_-_21923930 1.45 ENSDART00000131944
transgelin 3b
chr7_-_69352424 1.44 ENSDART00000170714
adaptor-related protein complex 1, gamma 1 subunit
chr23_-_21534738 1.44 ENSDART00000134587
regulator of chromosome condensation 2

Network of associatons between targets according to the STRING database.

First level regulatory network of mycn

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
2.0 9.9 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
1.9 5.8 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.9 7.6 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.8 5.4 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
1.8 5.4 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
1.5 8.8 GO:0044209 AMP salvage(GO:0044209)
1.4 4.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
1.3 7.8 GO:0043091 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
1.2 5.9 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.1 11.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
1.1 4.4 GO:0097037 heme export(GO:0097037)
1.0 4.0 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.9 3.8 GO:0034969 histone arginine methylation(GO:0034969)
0.9 3.7 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.9 2.7 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.9 6.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.9 3.5 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.8 4.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.8 2.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.8 3.9 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.8 2.3 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.7 14.8 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.6 1.9 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.6 15.0 GO:0009749 response to glucose(GO:0009749)
0.6 6.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.6 1.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.5 1.6 GO:0071514 genetic imprinting(GO:0071514)
0.5 2.7 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.5 5.8 GO:0030719 P granule organization(GO:0030719)
0.5 1.5 GO:0044771 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.5 6.6 GO:0009303 rRNA transcription(GO:0009303)
0.5 3.0 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.5 2.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.5 3.3 GO:0035627 ceramide transport(GO:0035627)
0.5 2.8 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.5 4.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.4 0.9 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.4 1.8 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.4 3.5 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.4 2.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.4 1.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.4 13.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.4 2.1 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.4 2.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.4 5.0 GO:0006670 sphingosine metabolic process(GO:0006670)
0.4 6.8 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.4 4.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.4 2.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 3.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 6.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 2.0 GO:0032218 riboflavin transport(GO:0032218)
0.3 2.7 GO:0044211 CTP salvage(GO:0044211)
0.3 1.0 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.3 1.0 GO:0015824 proline transport(GO:0015824)
0.3 1.9 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.3 1.2 GO:0006844 acyl carnitine transport(GO:0006844)
0.3 2.1 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.3 1.4 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.3 1.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.1 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3 9.8 GO:0030488 tRNA methylation(GO:0030488)
0.3 1.9 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.3 1.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.3 1.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 2.4 GO:0006415 translational termination(GO:0006415)
0.3 3.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 5.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.3 4.8 GO:0046686 response to cadmium ion(GO:0046686)
0.2 2.5 GO:0045117 azole transport(GO:0045117)
0.2 2.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.2 2.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 1.6 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.2 3.1 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 1.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 0.6 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.2 0.6 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.2 2.0 GO:0001510 RNA methylation(GO:0001510)
0.2 4.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 0.8 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 5.0 GO:0008272 sulfate transport(GO:0008272)
0.2 0.6 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.2 1.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 3.0 GO:0006265 DNA topological change(GO:0006265)
0.2 1.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 3.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 7.3 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 5.7 GO:0006400 tRNA modification(GO:0006400)
0.1 1.0 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 8.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 1.4 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 1.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.9 GO:0007141 male meiosis I(GO:0007141)
0.1 0.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.7 GO:0006788 heme oxidation(GO:0006788)
0.1 2.7 GO:0010883 regulation of lipid storage(GO:0010883)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.4 GO:0010165 response to X-ray(GO:0010165)
0.1 1.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 1.3 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 2.7 GO:0016925 protein sumoylation(GO:0016925)
0.1 6.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 1.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 1.7 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 1.3 GO:0030325 adrenal gland development(GO:0030325)
0.1 8.3 GO:0006364 rRNA processing(GO:0006364)
0.1 0.3 GO:0031053 primary miRNA processing(GO:0031053)
0.1 3.4 GO:0031647 regulation of protein stability(GO:0031647)
0.1 0.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.1 1.4 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.1 0.4 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.3 GO:0016038 absorption of visible light(GO:0016038)
0.1 0.4 GO:0015961 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.1 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.7 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 3.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.6 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.1 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 3.5 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.8 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.4 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 3.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 1.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.0 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 7.0 GO:0048882 lateral line development(GO:0048882)
0.0 0.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.7 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.6 GO:1902866 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.0 1.5 GO:0008033 tRNA processing(GO:0008033)
0.0 0.9 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.2 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 3.4 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.9 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.7 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.1 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 1.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 1.3 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013) GDP-mannose biosynthetic process(GO:0009298)
0.0 2.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 3.4 GO:0048511 rhythmic process(GO:0048511)
0.0 3.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.4 GO:0060079 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 0.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 2.5 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.7 GO:0043588 skin development(GO:0043588)
0.0 0.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 2.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.7 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 4.2 GO:0014032 neural crest cell development(GO:0014032)
0.0 0.6 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 2.0 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.6 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 2.1 GO:0006821 chloride transport(GO:0006821)
0.0 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.2 GO:0003341 cilium movement(GO:0003341)
0.0 0.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.7 GO:0043627 response to estrogen(GO:0043627) cellular response to estrogen stimulus(GO:0071391)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.6 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.3 GO:0097061 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 0.6 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 1.1 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 1.0 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.3 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.3 GO:0072114 pronephros morphogenesis(GO:0072114)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.4 4.2 GO:0034457 Mpp10 complex(GO:0034457)
1.4 7.0 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
1.4 4.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.0 5.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.9 3.7 GO:0035339 SPOTS complex(GO:0035339)
0.8 9.9 GO:0042627 chylomicron(GO:0042627)
0.7 2.7 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.6 13.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.6 1.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.6 1.7 GO:0033391 chromatoid body(GO:0033391)
0.5 2.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.5 2.5 GO:0018444 translation release factor complex(GO:0018444)
0.5 3.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.5 3.4 GO:0030681 ribonuclease MRP complex(GO:0000172) multimeric ribonuclease P complex(GO:0030681)
0.5 2.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 1.7 GO:0070195 growth hormone receptor complex(GO:0070195)
0.4 2.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.3 14.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 1.5 GO:0031415 NatA complex(GO:0031415)
0.3 4.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.3 4.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 12.6 GO:0005902 microvillus(GO:0005902)
0.2 5.0 GO:0032040 small-subunit processome(GO:0032040)
0.2 1.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 1.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 1.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 3.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 2.4 GO:0030686 90S preribosome(GO:0030686)
0.2 1.4 GO:0031931 TORC1 complex(GO:0031931)
0.2 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 2.1 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 4.4 GO:0043186 P granule(GO:0043186)
0.1 5.5 GO:0016605 PML body(GO:0016605)
0.1 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 33.4 GO:0005730 nucleolus(GO:0005730)
0.1 5.4 GO:0043204 perikaryon(GO:0043204)
0.1 2.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.5 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 1.0 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0000801 central element(GO:0000801)
0.1 0.8 GO:0035517 PR-DUB complex(GO:0035517)
0.1 1.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.6 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 3.6 GO:0030175 filopodium(GO:0030175)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.7 GO:0014704 intercalated disc(GO:0014704)
0.1 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.7 GO:0030904 retromer complex(GO:0030904)
0.1 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.9 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 2.2 GO:0005643 nuclear pore(GO:0005643)
0.0 5.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 3.0 GO:0005871 kinesin complex(GO:0005871)
0.0 3.3 GO:0000786 nucleosome(GO:0000786)
0.0 4.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 3.9 GO:0070382 exocytic vesicle(GO:0070382)
0.0 25.4 GO:0005829 cytosol(GO:0005829)
0.0 4.0 GO:0005938 cell cortex(GO:0005938)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.2 GO:0031514 motile cilium(GO:0031514)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031526 brush border membrane(GO:0031526)
0.0 3.4 GO:0005813 centrosome(GO:0005813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.6 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
2.0 9.9 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.8 5.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.6 4.8 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.4 7.0 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.4 4.1 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
1.2 3.5 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.1 7.8 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
1.1 5.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
1.0 3.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
1.0 3.8 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.9 4.7 GO:0004001 adenosine kinase activity(GO:0004001)
0.9 2.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.9 8.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.9 6.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.8 2.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.8 3.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.8 3.9 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.7 2.9 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.7 2.8 GO:0016842 amidine-lyase activity(GO:0016842)
0.7 3.3 GO:0039706 co-receptor binding(GO:0039706)
0.7 3.3 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.6 4.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.6 1.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.6 3.6 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.5 4.4 GO:0015232 heme transporter activity(GO:0015232)
0.5 6.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.5 2.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.5 2.1 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.5 2.4 GO:0008097 5S rRNA binding(GO:0008097)
0.5 1.4 GO:0034584 piRNA binding(GO:0034584)
0.5 2.3 GO:0016531 copper chaperone activity(GO:0016531)
0.5 1.4 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.4 3.4 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.4 1.7 GO:0004903 growth hormone receptor activity(GO:0004903)
0.4 1.2 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.4 2.5 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.4 5.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.4 1.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 1.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.4 9.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 2.0 GO:0032217 riboflavin transporter activity(GO:0032217)
0.3 2.7 GO:0004849 uridine kinase activity(GO:0004849)
0.3 1.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.3 2.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.3 5.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 4.3 GO:2001069 glycogen binding(GO:2001069)
0.3 3.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 1.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 1.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 3.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.3 5.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 7.6 GO:0008483 transaminase activity(GO:0008483)
0.3 3.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 3.5 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.2 8.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 3.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 1.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 1.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 3.5 GO:0031386 protein tag(GO:0031386)
0.2 2.6 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2 2.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.2 2.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 1.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 17.1 GO:0004540 ribonuclease activity(GO:0004540)
0.2 2.9 GO:0030515 snoRNA binding(GO:0030515)
0.2 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.2 1.8 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 2.1 GO:0070628 proteasome binding(GO:0070628)
0.1 2.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 6.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 3.8 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 2.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 3.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 6.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 2.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.7 GO:0099583 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.8 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.6 GO:0008301 DNA binding, bending(GO:0008301)
0.1 4.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 4.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.9 GO:0000049 tRNA binding(GO:0000049)
0.1 7.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.2 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 1.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 7.4 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 3.2 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.7 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 1.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 8.1 GO:0022834 ligand-gated ion channel activity(GO:0015276) ligand-gated channel activity(GO:0022834)
0.0 0.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.5 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752) dopamine receptor binding(GO:0050780)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 4.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 2.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 3.6 GO:0015293 symporter activity(GO:0015293)
0.0 0.4 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.6 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 10.9 GO:0003723 RNA binding(GO:0003723)
0.0 2.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 3.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 1.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 8.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 1.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 0.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 3.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.8 11.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.5 4.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.5 10.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.4 11.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 5.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 4.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 17.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.3 5.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 4.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 2.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 13.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 1.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 3.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 3.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 1.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 3.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 5.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 3.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 5.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 3.6 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.1 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 6.2 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 2.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 3.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 2.7 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants