Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for nfe2

Z-value: 0.72

Motif logo

Transcription factors associated with nfe2

Gene Symbol Gene ID Gene Info
ENSDARG00000020606 nuclear factor, erythroid 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfe2dr11_v1_chr23_-_36313431_363134310.113.1e-01Click!

Activity profile of nfe2 motif

Sorted Z-values of nfe2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_21877726 6.82 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr3_-_26017592 6.30 ENSDART00000030890
heme oxygenase 1a
chr3_-_26017831 5.91 ENSDART00000179982
heme oxygenase 1a
chr1_+_6640437 5.60 ENSDART00000147638
si:ch211-93g23.2
chr21_-_25756119 4.90 ENSDART00000002341
claudin c
chr19_+_8506178 4.84 ENSDART00000189689
S100 calcium binding protein A10a
chr9_-_23253870 4.80 ENSDART00000143657
ENSDART00000169911
aminocarboxymuconate semialdehyde decarboxylase
chr10_+_28428222 4.54 ENSDART00000135003
si:ch211-222e20.4
chr5_-_30615901 4.54 ENSDART00000147769
si:ch211-117m20.5
chr7_+_1045637 4.52 ENSDART00000111531
ependymin-like 1
chr5_+_42064144 4.49 ENSDART00000035235
si:ch211-202a12.4
chr4_+_25630555 4.32 ENSDART00000133425
acyl-CoA thioesterase 15
chr12_+_20587179 4.13 ENSDART00000170127
arylsulfatase G
chr20_-_15090862 4.03 ENSDART00000063892
ENSDART00000122592
si:dkey-239i20.2
chr15_-_26552652 3.99 ENSDART00000152336
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr9_-_33328948 3.91 ENSDART00000006948
ribosomal protein L8
chr10_+_26747755 3.87 ENSDART00000100329
coagulation factor IXb
chr21_-_2415808 3.79 ENSDART00000171179
si:ch211-241b2.5
chr5_-_44843738 3.70 ENSDART00000003926
fructose-1,6-bisphosphatase 1a
chr15_-_47929455 3.65 ENSDART00000064462
proteasome subunit alpha 6, like
chr25_+_10410620 3.50 ENSDART00000151886
ets homologous factor
chr16_+_46410520 3.47 ENSDART00000131072
rapunzel 2
chr20_-_48604621 3.42 ENSDART00000161769
ENSDART00000157871
microsomal glutathione S-transferase 3a
chr20_-_48604199 3.33 ENSDART00000161762
ENSDART00000170894
microsomal glutathione S-transferase 3a
chr2_+_4207209 3.33 ENSDART00000157903
ENSDART00000166476
GATA binding protein 6
chr12_-_16990896 3.17 ENSDART00000152402
interferon-induced protein with tetratricopeptide repeats 12
chr25_+_29474583 2.96 ENSDART00000191189
interleukin 17 receptor E-like
chr19_+_43119698 2.89 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eukaryotic translation elongation factor 1 alpha 1, like 1
chr1_-_52498146 2.83 ENSDART00000122217
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr4_-_71708855 2.69 ENSDART00000158819
si:dkeyp-4f2.1
chr7_+_57109214 2.68 ENSDART00000135068
ENSDART00000098412
enolase superfamily member 1
chr21_-_929293 2.63 ENSDART00000006419
thioredoxin-like 1
chr8_-_18010735 2.50 ENSDART00000125014
acyl-CoA thioesterase 11b
chr23_+_25292147 2.48 ENSDART00000131486
proliferation-associated 2G4, b
chr23_+_25291891 2.43 ENSDART00000016248
proliferation-associated 2G4, b
chr14_-_25985698 2.41 ENSDART00000172909
ENSDART00000123053
antioxidant 1 copper chaperone
chr25_+_29474982 2.41 ENSDART00000130410
interleukin 17 receptor E-like
chr17_+_32623931 2.34 ENSDART00000144217
cathepsin Ba
chr12_-_18898413 2.33 ENSDART00000181281
ENSDART00000121866
desumoylating isopeptidase 1b
chr23_+_9508538 2.30 ENSDART00000010697
oxysterol binding protein-like 2b
chr25_+_32474031 2.07 ENSDART00000152124
sulfide quinone oxidoreductase
chr8_-_50979047 2.01 ENSDART00000184788
ENSDART00000180906
zgc:91909
chr1_+_54655160 2.00 ENSDART00000190319
si:ch211-202h22.7
chr4_+_5317483 1.99 ENSDART00000150366
si:ch211-214j24.10
chr4_-_71708567 1.96 ENSDART00000182645
si:dkeyp-4f2.1
chr7_+_57108823 1.95 ENSDART00000184943
ENSDART00000055956
enolase superfamily member 1
chr2_-_6115389 1.88 ENSDART00000134921
peroxiredoxin 1
chr6_-_1587291 1.87 ENSDART00000067592
ENSDART00000178877
zgc:123305
chr14_-_38872536 1.85 ENSDART00000184315
ENSDART00000127479
glutathione reductase
chr10_+_7718156 1.85 ENSDART00000189101
gamma-glutamyl carboxylase
chr5_+_44805269 1.83 ENSDART00000136965
cathepsin La
chr7_+_17096903 1.82 ENSDART00000145357
ENSDART00000132706
HIV-1 Tat interactive protein 2
chr1_-_52497834 1.81 ENSDART00000136469
ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr13_-_37642890 1.81 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
chr21_-_929448 1.81 ENSDART00000133976
thioredoxin-like 1
chr20_-_35557902 1.76 ENSDART00000134753
adhesion G protein-coupled receptor F7
chr23_-_44546124 1.75 ENSDART00000126779
ENSDART00000024082
proteasome subunit beta 6
chr14_+_3507326 1.73 ENSDART00000159326
glutathione S-transferase pi 1
chr11_-_29936755 1.73 ENSDART00000145251
pirin
chr17_-_11439815 1.70 ENSDART00000130105
proteasome subunit alpha 3
chr17_+_33418475 1.70 ENSDART00000169145
synaptosomal-associated protein 23.1
chr3_+_23063718 1.70 ENSDART00000140225
ENSDART00000184431
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 1
chr14_-_38873095 1.70 ENSDART00000047050
ENSDART00000173285
ENSDART00000147521
glutathione reductase
chr25_-_35182347 1.70 ENSDART00000115210
anoctamin 9a
chr9_+_41103127 1.66 ENSDART00000000250
solute carrier family 40 (iron-regulated transporter), member 1
chr5_+_44804791 1.65 ENSDART00000122288
cathepsin La
chr19_-_10432134 1.63 ENSDART00000081440
interleukin 11b
chr20_-_16906623 1.62 ENSDART00000012859
ENSDART00000171628
proteasome subunit alpha 6b
chr6_-_425378 1.61 ENSDART00000192190
family with sequence similarity 83, member Fb
chr20_+_36629173 1.56 ENSDART00000161241
epoxide hydrolase 1, microsomal (xenobiotic)
chr13_+_42309688 1.54 ENSDART00000158367
insulin-degrading enzyme
chr19_-_10478229 1.49 ENSDART00000142937
si:ch211-171h4.5
chr23_+_9560797 1.49 ENSDART00000180014
adhesion regulating molecule 1
chr15_-_28677725 1.45 ENSDART00000060255
bleomycin hydrolase
chr5_+_44805028 1.39 ENSDART00000141198
cathepsin La
chr8_+_24747865 1.37 ENSDART00000078656
solute carrier family 16, member 4
chr23_+_9560991 1.36 ENSDART00000081433
ENSDART00000131594
ENSDART00000130069
ENSDART00000138601
adhesion regulating molecule 1
chr25_-_11378623 1.36 ENSDART00000166586
ectodermal-neural cortex 2
chr13_-_38039871 1.34 ENSDART00000140645

chr6_-_426041 1.34 ENSDART00000162789
family with sequence similarity 83, member Fb
chr6_-_52723901 1.31 ENSDART00000033949
oxidative stress responsive serine-rich 1
chr8_+_20825987 1.29 ENSDART00000133309
si:ch211-133l5.4
chr3_-_55525627 1.23 ENSDART00000189234
testis expressed 2
chr23_-_14769523 1.21 ENSDART00000054909
glutathione synthetase
chr8_+_3530761 1.19 ENSDART00000081272
GCN1 eIF2 alpha kinase activator homolog
chr24_-_23998897 1.18 ENSDART00000130053
zmp:0000000991
chr4_-_60780423 1.15 ENSDART00000162632
si:dkey-254e13.6
chr14_+_49395437 1.14 ENSDART00000172850
TNFAIP3 interacting protein 1
chr24_-_1657276 1.14 ENSDART00000168131
si:ch73-378g22.1
chr21_-_5393125 1.13 ENSDART00000146061
proteasome 26S subunit, non-ATPase 5
chr4_-_36476889 1.10 ENSDART00000163956
si:ch211-263l8.1
chr4_-_71913556 1.09 ENSDART00000167608
si:dkey-92c21.1
chr2_-_6115688 1.01 ENSDART00000081663
peroxiredoxin 1
chr6_+_9421279 1.00 ENSDART00000161036
kalirin RhoGEF kinase b
chr7_-_2116512 0.99 ENSDART00000098148
si:cabz01007802.1
chr11_-_23501467 0.99 ENSDART00000169066
pleckstrin homology domain containing, family A member 6
chr8_-_36399884 0.98 ENSDART00000108538
si:zfos-2070c2.3
chr5_-_67471375 0.98 ENSDART00000147009
si:dkey-251i10.2
chr4_-_1757460 0.98 ENSDART00000144074
transmembrane 7 superfamily member 3
chr14_-_7207961 0.95 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr4_-_50930346 0.94 ENSDART00000184245
si:ch211-208f21.3
chr13_+_7241170 0.94 ENSDART00000109434
apoptosis-inducing factor, mitochondrion-associated, 2
chr14_+_30279391 0.93 ENSDART00000172794
fibrinogen-like 1
chr15_+_25438714 0.92 ENSDART00000154164
apoptosis-inducing factor, mitochondrion-associated, 4
chr4_-_36033377 0.91 ENSDART00000164348
ENSDART00000187058
zgc:174180
chr3_-_34816893 0.90 ENSDART00000084448
ENSDART00000154696
proteasome 26S subunit, non-ATPase 11a
chr13_+_25397098 0.90 ENSDART00000132953
glutathione S-transferase omega 2
chr24_-_24281792 0.89 ENSDART00000146482
ENSDART00000018420
pyruvate dehydrogenase E1 alpha 1 subunit b
chr19_-_41404870 0.87 ENSDART00000167772
SEM1, 26S proteasome complex subunit
chr4_-_36032930 0.86 ENSDART00000191414
zgc:174180
chr6_+_53288018 0.86 ENSDART00000170319
cysteinyl leukotriene receptor 3
chr4_+_34121902 0.86 ENSDART00000170225
si:ch211-223g7.6
chr3_-_55139127 0.85 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr22_+_19528851 0.83 ENSDART00000145079
si:dkey-78l4.13
chr4_+_42878556 0.82 ENSDART00000171047
si:zfos-451d2.2
chr13_+_25396896 0.82 ENSDART00000041257
glutathione S-transferase omega 2
chr8_-_21056012 0.81 ENSDART00000142852
zgc:112962
chr20_-_16972351 0.80 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
chr15_+_19885498 0.76 ENSDART00000152123
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
chr4_+_54645654 0.76 ENSDART00000192864
si:ch211-227e10.1
chr25_-_35045250 0.76 ENSDART00000156508
ENSDART00000126590
zgc:114046
chr21_+_45316330 0.76 ENSDART00000056474
ENSDART00000149314
ENSDART00000149272
ENSDART00000149156
ENSDART00000099497
transcription factor 7
chr11_+_43401201 0.76 ENSDART00000190128
vasoactive intestinal peptide b
chr2_-_36494308 0.75 ENSDART00000110378

chr15_+_25439106 0.74 ENSDART00000156252
apoptosis-inducing factor, mitochondrion-associated, 4
chr4_-_20292821 0.71 ENSDART00000136069
ENSDART00000192504
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr9_+_6937569 0.71 ENSDART00000146383
major facilitator superfamily domain containing 9
chr21_-_28640316 0.69 ENSDART00000128237
neuregulin 2a
chr8_+_4434422 0.67 ENSDART00000145184
SRR1 domain containing
chr6_-_32349153 0.61 ENSDART00000140004
angiopoietin-like 3
chr4_-_70308067 0.60 ENSDART00000165967
ENSDART00000134334
si:dkey-3h2.3
si:ch211-11p18.6
chr9_-_12885201 0.59 ENSDART00000124957
ankyrin repeat and zinc finger domain containing 1
chr7_+_17992640 0.58 ENSDART00000173679
EH domain binding protein 1-like 1a
chr4_-_39448829 0.56 ENSDART00000168526
si:dkey-261o4.9
chr16_+_9762261 0.55 ENSDART00000020654
proteasome 26S subunit, non-ATPase 4b
chr16_+_13883872 0.54 ENSDART00000101304
ENSDART00000136005
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr17_-_12966907 0.54 ENSDART00000022874
proteasome subunit alpha 6a
chr24_+_24086249 0.53 ENSDART00000002953
lipase, member Ib
chr19_-_32937582 0.52 ENSDART00000144721
antizyme inhibitor 1b
chr3_-_53533128 0.51 ENSDART00000183591
notch 3
chr22_+_9027884 0.50 ENSDART00000171839
si:ch211-213a13.2
chr21_-_2621127 0.48 ENSDART00000172363
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein b
chr8_-_21058354 0.48 ENSDART00000130481
ENSDART00000113749
zgc:112962
chr7_+_1442059 0.47 ENSDART00000173391
si:cabz01090193.1
chr21_-_23110841 0.45 ENSDART00000147896
ENSDART00000003076
ENSDART00000184925
ENSDART00000190386
ubiquitin specific peptidase 28
chr15_-_1590858 0.44 ENSDART00000081875
nanor
chr21_-_24865217 0.43 ENSDART00000101136
immunoglobulin superfamily, member 9Bb
chr2_+_8261109 0.42 ENSDART00000024677
deleted in autism 1a
chr15_+_44283723 0.42 ENSDART00000167722
CWF19-like 2, cell cycle control (S. pombe)
chr8_+_22859718 0.40 ENSDART00000134151
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr25_+_33046060 0.38 ENSDART00000165345
talin 2b
chr7_+_17992455 0.33 ENSDART00000089211
ENSDART00000190881
EH domain binding protein 1-like 1a
chr3_+_58092212 0.30 ENSDART00000156059
si:ch211-256e16.7
chr9_+_22466218 0.28 ENSDART00000131214
diacylglycerol kinase, gamma
chr12_+_48216662 0.27 ENSDART00000187369
leucine rich repeat containing 20
chr2_-_26642831 0.27 ENSDART00000132854
ENSDART00000087714
ENSDART00000132651
U2 snRNP-associated SURP domain containing
chr18_-_2222128 0.27 ENSDART00000171402
phosphatidylinositol glycan anchor biosynthesis, class B
chr10_-_19523752 0.25 ENSDART00000160057
si:ch211-127i16.2
chr11_+_43401592 0.24 ENSDART00000112468
vasoactive intestinal peptide b
chr16_-_41804606 0.23 ENSDART00000134718
proteasome 26S subunit, ATPase 4
chr7_+_756942 0.23 ENSDART00000152224
zgc:63470
chr21_-_11286483 0.22 ENSDART00000074845
rhotekin 2b
chr2_-_31800521 0.21 ENSDART00000112763
reticulophagy regulator 1
chr17_+_7524389 0.21 ENSDART00000067579
kelch-like family member 10b, tandem duplicate 2
chr17_-_23673864 0.19 ENSDART00000104738
ENSDART00000128958
phosphatase and tensin homolog A
chr11_+_2198831 0.19 ENSDART00000160515
homeobox C6b
chr13_+_2357637 0.18 ENSDART00000017148
glutamate-cysteine ligase, catalytic subunit
chr16_-_7692568 0.17 ENSDART00000148980
Pim proto-oncogene, serine/threonine kinase, related 209
chr19_-_19379084 0.16 ENSDART00000165206
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr18_+_33009828 0.16 ENSDART00000160100
olfactory receptor C family, j1
chr5_-_16405651 0.15 ENSDART00000163942
solute carrier family 39 (zinc transporter), member 14
chr23_+_44546319 0.12 ENSDART00000139088
ENSDART00000056935
trafficking protein particle complex 1
chr1_+_19849168 0.09 ENSDART00000111454
si:dkey-82j4.2
chr20_-_26866111 0.09 ENSDART00000077767
myosin light chain kinase family, member 4b
chr3_+_26064091 0.08 ENSDART00000143697
si:dkeyp-69e1.8
chr24_-_9689915 0.08 ENSDART00000185972
ENSDART00000093046
ubiquitin-like modifier activating enzyme 5
chr17_-_23674065 0.07 ENSDART00000104735
ENSDART00000182952
phosphatase and tensin homolog A
chr22_-_14696667 0.07 ENSDART00000180379
low density lipoprotein receptor-related protein 1Ba
chr11_+_13630107 0.05 ENSDART00000172220
si:ch211-1a19.3
chr18_+_45571378 0.05 ENSDART00000077251
kinesin family member C3
chr10_+_29265463 0.04 ENSDART00000155390
CREB/ATF bZIP transcription factor
chr20_-_19532531 0.03 ENSDART00000125830
ENSDART00000179566
ENSDART00000184193
eukaryotic translation initiation factor 2B, subunit 4 delta

chr6_+_33885828 0.03 ENSDART00000179994
GC-rich promoter binding protein 1-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of nfe2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
1.4 6.8 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
1.2 3.7 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.8 4.8 GO:0019805 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.7 2.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.7 3.3 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.4 1.7 GO:0030224 monocyte differentiation(GO:0030224)
0.4 1.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.4 6.3 GO:0043248 proteasome assembly(GO:0043248)
0.4 1.7 GO:0010039 response to iron ion(GO:0010039)
0.3 1.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 3.8 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.3 1.8 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 2.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.3 2.9 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.3 8.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.3 1.0 GO:0048241 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.2 1.5 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.2 0.8 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.2 1.7 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.2 0.5 GO:0035019 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.2 0.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.2 0.6 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.9 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 1.5 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 5.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.7 GO:0098773 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.1 0.5 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.4 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.5 GO:0009636 response to toxic substance(GO:0009636)
0.1 6.4 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 1.9 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 1.7 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.3 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 0.2 GO:0033212 iron assimilation(GO:0033212)
0.1 1.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 4.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 3.9 GO:0007596 blood coagulation(GO:0007596)
0.0 1.1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 3.2 GO:0051607 defense response to virus(GO:0051607)
0.0 0.7 GO:0046549 retinal cone cell development(GO:0046549)
0.0 3.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 4.6 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 3.5 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 0.2 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 4.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.9 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.9 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.2 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 2.3 GO:0031101 fin regeneration(GO:0031101)
0.0 0.4 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 1.3 GO:0051170 nuclear import(GO:0051170)
0.0 1.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.5 6.8 GO:0042627 chylomicron(GO:0042627)
0.4 4.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 1.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 2.0 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 3.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 11.4 GO:0005764 lysosome(GO:0005764)
0.0 0.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 4.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 2.5 GO:0000786 nucleosome(GO:0000786)
0.0 1.0 GO:0043204 perikaryon(GO:0043204)
0.0 1.7 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.7 GO:0031201 SNARE complex(GO:0031201)
0.0 1.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.4 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 12.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.4 6.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.2 3.7 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.7 3.6 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.7 2.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.6 1.7 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.5 1.6 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.5 2.4 GO:0016531 copper chaperone activity(GO:0016531)
0.5 2.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.5 1.8 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.4 4.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 5.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 4.6 GO:0004046 aminoacylase activity(GO:0004046)
0.4 2.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 2.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.3 0.9 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3 6.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 4.5 GO:0031386 protein tag(GO:0031386)
0.2 1.2 GO:0043295 glutathione binding(GO:0043295)
0.2 1.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 4.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 0.9 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 5.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 4.3 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 3.9 GO:0019843 rRNA binding(GO:0019843)
0.1 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.3 GO:0051800 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 4.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 1.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 1.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 4.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 4.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 11.1 GO:0004175 endopeptidase activity(GO:0004175)
0.0 1.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.2 GO:0043022 ribosome binding(GO:0043022)
0.0 1.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 1.5 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 4.9 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.3 GO:0008083 growth factor activity(GO:0008083)
0.0 2.9 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.9 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 2.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 4.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 4.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 1.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 3.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 3.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis