Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for nfixa+nfixb

Z-value: 0.96

Motif logo

Transcription factors associated with nfixa+nfixb

Gene Symbol Gene ID Gene Info
ENSDARG00000043226 nuclear factor I/Xa
ENSDARG00000061836 nuclear factor I/Xb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfixbdr11_v1_chr3_+_14768364_14768364-0.188.2e-02Click!
nfixadr11_v1_chr1_+_51903413_51903413-0.161.1e-01Click!

Activity profile of nfixa+nfixb motif

Sorted Z-values of nfixa+nfixb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_17672527 17.54 ENSDART00000148269
ENSDART00000137776
catechol-O-methyltransferase domain containing 1
chr13_-_20381485 11.66 ENSDART00000131351
si:ch211-270n8.1
chr22_+_38229321 11.44 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
chr12_-_22524388 11.14 ENSDART00000020942
sex hormone-binding globulin
chr11_-_3629201 10.54 ENSDART00000136577
ENSDART00000132121
inter-alpha-trypsin inhibitor heavy chain 3a
chr14_+_29975268 10.41 ENSDART00000172985
cytochrome P450, family 4, subfamily V, polypeptide 7
chr13_-_9895564 10.03 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
chr20_+_25581627 9.89 ENSDART00000030229
cytochrome P450, family 2, subfamily P, polypeptide 9
chr4_-_8030583 9.47 ENSDART00000113628
si:ch211-240l19.8
chr25_-_26018424 8.72 ENSDART00000089332
acyl-CoA synthetase bubblegum family member 1
chr14_+_11457500 7.99 ENSDART00000169202
si:ch211-153b23.5
chr14_-_25444774 7.32 ENSDART00000183448
solute carrier family 26 (anion exchanger), member 2
chr14_+_11458044 7.31 ENSDART00000186425
si:ch211-153b23.5
chr2_-_3437862 7.20 ENSDART00000053012
cytochrome P450, family 8, subfamily B, polypeptide 1
chr3_-_39198113 7.13 ENSDART00000102690
zgc:154169
chr25_-_26018240 7.04 ENSDART00000150800
acyl-CoA synthetase bubblegum family member 1
chr3_-_40976288 7.03 ENSDART00000193553
cytochrome P450, family 3, subfamily c, polypeptide 1
chr1_-_9644630 6.98 ENSDART00000123725
ENSDART00000161164
UDP glucuronosyltransferase 5 family, polypeptide B3
chr3_-_32541033 6.58 ENSDART00000151476
ENSDART00000055324
reticulocalbin 3, EF-hand calcium binding domain
chr25_-_30429607 6.57 ENSDART00000162429
ENSDART00000176535
si:ch211-93f2.1
chr20_+_26880668 6.08 ENSDART00000077769
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr6_-_49078263 5.95 ENSDART00000032982
solute carrier family 5 (iodide transporter), member 8-like
chr3_-_36750068 5.79 ENSDART00000173388
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr10_+_39263827 5.62 ENSDART00000172509
FAD-dependent oxidoreductase domain containing 1
chr25_-_30394746 5.58 ENSDART00000185346
si:ch211-93f2.1
chr22_+_19553390 5.31 ENSDART00000061739
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr17_+_16873417 5.15 ENSDART00000146276
iodothyronine deiodinase 2
chr22_-_15602760 4.83 ENSDART00000009054
tropomyosin 4a
chr4_+_17279966 4.82 ENSDART00000067005
ENSDART00000137487
branched chain amino-acid transaminase 1, cytosolic
chr19_-_42556086 4.77 ENSDART00000051731
si:dkey-267n13.1
chr9_+_38292947 4.73 ENSDART00000146663
transcription factor CP2-like 1
chr13_+_18545819 4.66 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
chr25_+_7494181 4.61 ENSDART00000165005
catalase
chr5_+_31965845 4.19 ENSDART00000112968
myosin IHb
chr5_+_57328535 3.78 ENSDART00000149646
solute carrier family 31 (copper transporter), member 1
chr2_-_41861040 3.76 ENSDART00000045763
kelch-like ECH-associated protein 1a
chr22_+_34663328 3.68 ENSDART00000183912
si:ch73-304f21.1
chr22_+_5478353 3.67 ENSDART00000160596
tubulin polymerization promoting protein
chr4_-_8040436 3.63 ENSDART00000113033
si:ch211-240l19.6
chr14_-_21064199 3.07 ENSDART00000172099
si:dkey-74k8.3
chr6_+_40437987 3.04 ENSDART00000136487
ghrelin/obestatin prepropeptide
chr14_+_28438947 2.84 ENSDART00000006489
acyl-CoA synthetase long chain family member 4a
chr5_+_20319519 2.75 ENSDART00000004217
coronin, actin binding protein, 1Ca
chr13_+_15682803 2.74 ENSDART00000188063

chr16_+_7697878 2.72 ENSDART00000104176
ENSDART00000172977
chemokine (C-C motif) receptor 11.1
chr11_-_28086915 2.65 ENSDART00000161894
si:ch211-220m17.4
chr21_+_19858627 2.47 ENSDART00000147010
FYN binding protein b
chr16_+_38394371 2.46 ENSDART00000137954
CD83 molecule
chr19_-_13962469 2.43 ENSDART00000159062
progestin and adipoQ receptor family member VII, a
chr25_-_11378623 2.43 ENSDART00000166586
ectodermal-neural cortex 2
chr7_+_61184551 2.40 ENSDART00000190788
zgc:194930
chr6_-_24301324 2.33 ENSDART00000171401

chr14_+_22076596 2.30 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr6_-_27108844 2.20 ENSDART00000073883
deoxythymidylate kinase (thymidylate kinase)
chr22_-_15602593 2.19 ENSDART00000036075
tropomyosin 4a
chr11_+_14333441 2.19 ENSDART00000171969
polypyrimidine tract binding protein 1b
chr15_-_18361475 2.19 ENSDART00000155866
zinc finger and BTB domain containing 16b
chr19_+_10603405 2.17 ENSDART00000151135
si:dkey-211g8.8
chr16_+_27444098 2.16 ENSDART00000157690
inversin
chr5_+_26121393 2.14 ENSDART00000002221
beta-carotene 15, 15-dioxygenase 2, like
chr11_-_24016761 2.09 ENSDART00000153601
ENSDART00000067817
ENSDART00000170531
chitinase, acidic.3
chr4_-_52189449 2.08 ENSDART00000192426

chr23_-_26880623 2.06 ENSDART00000038491
adenylate cyclase 6b
chr23_+_21414005 2.06 ENSDART00000144686
intermediate filament family orphan 2a
chr1_-_54706039 2.00 ENSDART00000083633
exosome component 1
chr6_+_8630355 1.99 ENSDART00000161749
ENSDART00000193976
thrombospondin-type laminin G domain and EAR repeats a
chr13_+_18321140 1.98 ENSDART00000180947
eukaryotic translation initiation factor 4E family member 1c
chr3_+_54744069 1.97 ENSDART00000134958
ENSDART00000114443
si:ch211-74m13.3
chr7_+_61184104 1.85 ENSDART00000110671
zgc:194930
chr6_+_39905021 1.85 ENSDART00000064904
endonuclease, polyU-specific
chr23_+_19790962 1.81 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr2_-_37477654 1.79 ENSDART00000193921
death-associated protein kinase 3
chr16_+_46430627 1.74 ENSDART00000127681
rapunzel 6
chr3_+_43955864 1.72 ENSDART00000168267

chr11_+_43740949 1.71 ENSDART00000189296

chr19_-_27858033 1.70 ENSDART00000103898
ENSDART00000144884
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr7_-_5207152 1.68 ENSDART00000172751
si:ch73-223f5.2
chr7_+_59649399 1.65 ENSDART00000123520
ENSDART00000040771
ribosomal protein L34
chr21_-_36619599 1.63 ENSDART00000065208
NOP16 nucleolar protein homolog (yeast)
chr11_-_11890001 1.62 ENSDART00000081544
WAS/WASL interacting protein family, member 2a
chr8_+_20140321 1.54 ENSDART00000012120
acyl-CoA synthetase bubblegum family member 2
chr25_+_16194450 1.50 ENSDART00000141994
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr8_+_28469054 1.49 ENSDART00000062716
solute carrier family 52 (riboflavin transporter), member 3
chr7_+_57108823 1.47 ENSDART00000184943
ENSDART00000055956
enolase superfamily member 1
chr12_+_26632448 1.45 ENSDART00000185762
Rho GTPase activating protein 12b
chr2_-_37889111 1.41 ENSDART00000168939
ENSDART00000098529
mannose binding lectin 2
chr11_+_23704410 1.39 ENSDART00000112655
neurofascin homolog (chicken) a
chr5_-_24517768 1.37 ENSDART00000003957
cytotoxic granule-associated RNA binding protein 1, like
chr5_-_33255759 1.37 ENSDART00000085531
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr9_-_28937880 1.33 ENSDART00000132878
erythrocyte membrane protein band 4.1 like 5
chr19_-_12404590 1.33 ENSDART00000103703
finTRIM family, member 56
chr9_+_6587364 1.32 ENSDART00000122279
four and a half LIM domains 2a
chr1_-_58900851 1.31 ENSDART00000183085
ENSDART00000188855
ENSDART00000182567
Danio rerio microfibril-associated glycoprotein 4-like (LOC100334800), transcript variant 2, mRNA.
chr16_+_48682309 1.30 ENSDART00000183957
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_35052145 1.27 ENSDART00000073970
ENSDART00000185790
UDP-N-acetylglucosamine pyrophosphorylase 1
chr16_-_17660594 1.25 ENSDART00000011936
coiled-coil domain containing 106a
chr7_-_39751540 1.25 ENSDART00000016803
GrpE-like 1, mitochondrial
chr4_+_25680480 1.24 ENSDART00000100737
acyl-CoA thioesterase 17
chr16_-_45209684 1.23 ENSDART00000184595
FXYD domain containing ion transport regulator 1 (phospholemman)
chr2_-_3616363 1.23 ENSDART00000144699
phosphotriesterase related
chr6_+_32834760 1.22 ENSDART00000121562
cylindromatosis (turban tumor syndrome), like
chr19_+_14109348 1.21 ENSDART00000159015
zgc:175136
chr14_-_24101897 1.21 ENSDART00000143695
cytoplasmic polyadenylation element binding protein 4a
chr21_+_27448856 1.19 ENSDART00000100784
complement factor b-like
chr3_+_32416948 1.18 ENSDART00000157324
ENSDART00000154267
ENSDART00000186094
ENSDART00000155860
ENSDART00000156986
proline rich Gla (G-carboxyglutamic acid) 2
chr11_-_20956309 1.15 ENSDART00000188659

chr16_+_23961276 1.15 ENSDART00000192754
apolipoprotein Eb
chr7_+_12835048 1.14 ENSDART00000016465
connexin 36.7
chr18_-_48983690 1.11 ENSDART00000182359

chr5_-_10239079 1.10 ENSDART00000132739
si:ch73-42k18.1
chr2_-_51757328 1.07 ENSDART00000189286
si:ch211-9d9.1
chr1_+_19933065 1.06 ENSDART00000161573
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr15_+_38308421 1.05 ENSDART00000129941
si:dkey-24p1.6
chr24_+_15655233 1.03 ENSDART00000143160
F-box protein 15
chr2_-_42375275 1.01 ENSDART00000026339
GTP binding protein 4
chr7_+_26326462 1.00 ENSDART00000173515
zonadhesin, like
chr12_+_26471712 0.98 ENSDART00000162115
nudE neurodevelopment protein 1-like 1a
chr19_+_4463389 0.98 ENSDART00000168805
potassium channel, subfamily K, member 9
chr17_-_465285 0.98 ENSDART00000168718
cholinergic receptor, muscarinic 5a
chr19_-_25464291 0.96 ENSDART00000112915
UBAP1-MVB12-associated (UMA) domain containing 1
chr7_-_21928826 0.95 ENSDART00000088043
si:dkey-85k7.11
chr18_+_20468157 0.95 ENSDART00000100665
ENSDART00000147867
ENSDART00000060302
ENSDART00000180370
damage-specific DNA binding protein 2
chr16_+_23960933 0.93 ENSDART00000146077
apolipoprotein Eb
chr2_+_40294313 0.92 ENSDART00000037292
eph receptor A4b
chr17_+_50701748 0.90 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermitin family member 2
chr14_+_40874608 0.89 ENSDART00000168448
si:ch211-106m9.1
chr18_+_45542981 0.84 ENSDART00000140357
kinesin family member C3
chr6_-_15096556 0.84 ENSDART00000185327
four and a half LIM domains 2b
chr19_-_9786914 0.83 ENSDART00000181669
si:dkey-14o18.2
chr19_-_29832876 0.83 ENSDART00000005119
eukaryotic translation initiation factor 3, subunit I
chr23_+_27789795 0.82 ENSDART00000141458
lysine (K)-specific methyltransferase 2D
chr6_-_1587291 0.82 ENSDART00000067592
ENSDART00000178877
zgc:123305
chr11_-_13151841 0.81 ENSDART00000161983
ELOVL fatty acid elongase 1b
chr9_+_21993092 0.79 ENSDART00000059693
crystallin, gamma M7
chr25_+_10953351 0.79 ENSDART00000154050
major histocompatibility complex class I LDA
chr2_-_51330642 0.79 ENSDART00000163043
si:dkeyp-104b3.21
chr2_-_14798295 0.76 ENSDART00000143430
ENSDART00000145869
si:ch73-366i20.1
chr17_+_37249736 0.75 ENSDART00000189686

chr23_-_24047054 0.74 ENSDART00000184308
ENSDART00000185902

chr4_+_28997595 0.74 ENSDART00000133357
si:dkey-13e3.1
chr17_-_14451718 0.73 ENSDART00000039438
jnk1/mapk8 associated membrane protein
chr5_+_20693724 0.72 ENSDART00000141368
si:ch211-240b21.2
chr3_-_55139127 0.72 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr11_-_22372072 0.71 ENSDART00000065996
transmembrane protein 183A
chr7_-_8416750 0.69 ENSDART00000181857
jacalin 1
chr2_-_14793343 0.69 ENSDART00000132264
si:ch73-366i20.1
chr16_-_49846359 0.68 ENSDART00000184246
zinc finger protein 385D
chr22_-_35330532 0.68 ENSDART00000172654

chr10_-_17988779 0.68 ENSDART00000132206
ENSDART00000144841
si:dkey-242g16.2
chr13_-_33683889 0.67 ENSDART00000136820
ENSDART00000065435
cystatin C (amyloid angiopathy and cerebral hemorrhage)
chr4_-_77274225 0.67 ENSDART00000174208

chr19_-_24443867 0.67 ENSDART00000163763
ENSDART00000043133
thrombospondin 3b
chr24_-_23998897 0.67 ENSDART00000130053
zmp:0000000991
chr14_+_39255437 0.66 ENSDART00000147443
diaphanous-related formin 2
chr11_-_17964525 0.66 ENSDART00000018948
cytokine inducible SH2-containing protein b
chr5_-_30984271 0.66 ENSDART00000051392
spinster homolog 3 (Drosophila)
chr23_+_36616717 0.66 ENSDART00000042701
ENSDART00000192980
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr24_-_30862168 0.64 ENSDART00000168540
polypyrimidine tract binding protein 2a
chr22_+_10163901 0.62 ENSDART00000190468
ribonuclease P/MRP 14 subunit
chr7_+_59212666 0.62 ENSDART00000172046
docking protein 1b
chr15_+_41836104 0.62 ENSDART00000137434
2-phosphoxylose phosphatase 1
chr17_+_35431724 0.61 ENSDART00000190293

chr22_-_37611681 0.60 ENSDART00000028085
tetratricopeptide repeat domain 14
chr3_+_34988670 0.58 ENSDART00000011319
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr11_+_44579865 0.56 ENSDART00000173425
nidogen 1b
chr5_+_45918680 0.56 ENSDART00000036242
ankyrin repeat and death domain containing 1B
chr21_-_25555355 0.55 ENSDART00000144228
si:dkey-17e16.9
chr3_+_52467879 0.54 ENSDART00000156039
adhesion G protein-coupled receptor E5a
chr15_+_37986069 0.54 ENSDART00000156984
si:dkey-238d18.8
chr18_-_33093705 0.53 ENSDART00000059500
olfactory receptor C family, d3
chr15_-_31027112 0.53 ENSDART00000100185
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 4
chr5_+_16580739 0.52 ENSDART00000135140
5-hydroxytryptamine (serotonin) receptor 7c
chr3_-_32603191 0.52 ENSDART00000150997
si:ch73-248e21.7
chr2_+_9536021 0.51 ENSDART00000187357

chr24_+_1294176 0.49 ENSDART00000106637
si:ch73-134f24.1
chr25_-_27729046 0.48 ENSDART00000131437
zgc:153935
chr12_+_30723778 0.47 ENSDART00000153291
solute carrier family 35, member F3a
chr23_+_28381260 0.46 ENSDART00000162722
zgc:153867
chr19_+_10831362 0.46 ENSDART00000053325
translocase of outer mitochondrial membrane 40 homolog, like
chr1_-_33645967 0.46 ENSDART00000192758
claudin g
chr14_+_15484544 0.46 ENSDART00000188649

chr3_+_31600593 0.45 ENSDART00000076640
ENSDART00000148189
coiled-coil domain containing 43
chr6_-_51541488 0.44 ENSDART00000156336
si:dkey-6e2.2
chr1_+_36651059 0.44 ENSDART00000187475
endothelin receptor type Aa
chr2_-_51330414 0.43 ENSDART00000186450
si:dkeyp-104b3.21
chr20_-_47188966 0.43 ENSDART00000152965
si:dkeyp-104f11.9
chr3_-_8765165 0.43 ENSDART00000191131

chr9_-_32191620 0.42 ENSDART00000139426
Pim proto-oncogene, serine/threonine kinase, related 143
chr12_-_17424162 0.42 ENSDART00000079144
ENSDART00000079138
phosphatase and tensin homolog B
chr12_-_6880694 0.42 ENSDART00000171846
protocadherin-related 15b
chr17_-_27223965 0.42 ENSDART00000192577
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr9_+_15890558 0.39 ENSDART00000144032
si:dkey-14o1.20
chr4_-_72100774 0.38 ENSDART00000170099
solute carrier organic anion transporter family, member 1F1
chr5_-_23878809 0.38 ENSDART00000160603
si:ch211-135f11.4
chr23_+_22293682 0.38 ENSDART00000187304

chr11_-_13152215 0.37 ENSDART00000160989
ENSDART00000158239
ELOVL fatty acid elongase 1b
chr22_+_12477996 0.37 ENSDART00000177704

chr7_-_26457208 0.37 ENSDART00000173519
zgc:172079
chr19_+_17642356 0.37 ENSDART00000176431

chr4_+_17655872 0.36 ENSDART00000066999
WASH complex subunit 3

Network of associatons between targets according to the STRING database.

First level regulatory network of nfixa+nfixb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.9 9.6 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
1.2 4.8 GO:0009098 leucine biosynthetic process(GO:0009098)
0.8 2.5 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.8 18.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.8 3.8 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.7 5.2 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.7 2.2 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.7 2.1 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.6 3.1 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.5 2.2 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.5 2.8 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.4 3.8 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.3 1.3 GO:0019884 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.3 3.0 GO:0032095 regulation of response to food(GO:0032095)
0.3 5.6 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3 7.2 GO:0008272 sulfate transport(GO:0008272)
0.3 1.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 1.5 GO:0032218 riboflavin transport(GO:0032218)
0.2 2.1 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.2 7.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 3.5 GO:0046688 response to copper ion(GO:0046688)
0.2 2.5 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.2 9.9 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.2 2.1 GO:0006032 chitin catabolic process(GO:0006032)
0.2 1.2 GO:0002931 response to ischemia(GO:0002931)
0.2 1.3 GO:0021744 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.2 1.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.6 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 0.9 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 0.5 GO:2000561 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 9.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 1.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 2.8 GO:0090148 membrane fission(GO:0090148)
0.1 1.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.8 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 7.2 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.1 0.4 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 2.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 2.1 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.1 4.2 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 0.4 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 18.3 GO:0006914 autophagy(GO:0006914)
0.1 1.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 2.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.6 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 16.7 GO:0032259 methylation(GO:0032259)
0.1 1.6 GO:0030048 actin filament-based movement(GO:0030048)
0.0 1.7 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 1.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.9 GO:0009411 response to UV(GO:0009411)
0.0 0.9 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.2 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.7 GO:0015671 oxygen transport(GO:0015671)
0.0 1.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.4 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 2.0 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 1.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 2.4 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.2 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 2.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.8 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 1.6 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 1.5 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.6 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0016234 inclusion body(GO:0016234)
0.5 2.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.3 1.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 0.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 2.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 0.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 2.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 4.2 GO:0005902 microvillus(GO:0005902)
0.1 8.6 GO:0005884 actin filament(GO:0005884)
0.1 2.8 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 2.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.5 GO:0019814 immunoglobulin complex(GO:0019814)
0.0 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 2.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 4.6 GO:0005764 lysosome(GO:0005764)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 10.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 5.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
1.3 17.3 GO:0016405 CoA-ligase activity(GO:0016405)
1.2 4.9 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
1.2 4.8 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.8 3.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.7 9.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.7 2.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.7 2.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.6 17.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.5 4.6 GO:0004096 catalase activity(GO:0004096)
0.4 1.7 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.4 7.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 2.6 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.3 1.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 1.3 GO:0015440 peptide antigen-transporting ATPase activity(GO:0015433) peptide-transporting ATPase activity(GO:0015440) TAP binding(GO:0046977)
0.3 16.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.3 2.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.3 1.3 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.3 10.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 1.5 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 1.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 2.1 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 5.3 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.2 2.1 GO:0004568 chitinase activity(GO:0004568)
0.2 11.1 GO:0042562 hormone binding(GO:0042562)
0.2 0.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.4 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 11.1 GO:0020037 heme binding(GO:0020037)
0.1 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 4.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 2.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 2.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 2.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 6.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 1.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 6.2 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)
0.0 0.5 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.6 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 3.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.6 GO:0043492 P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.7 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 3.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.9 GO:0044389 ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 1.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 4.6 PID FOXO PATHWAY FoxO family signaling
0.1 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 4.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.9 4.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.5 5.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 4.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 3.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 1.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 1.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 2.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 1.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 3.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 7.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.3 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis