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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nkx2.1

Z-value: 0.69

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Transcription factors associated with nkx2.1

Gene Symbol Gene ID Gene Info
nkx2.1
ENSDARG00000019835 NK2 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.1dr11_v1_chr17_+_38262408_38262408-0.286.9e-03Click!

Activity profile of nkx2.1 motif

Sorted Z-values of nkx2.1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_51597677 13.13 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr5_+_51594209 11.15 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr22_-_278328 9.61 ENSDART00000098072
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr22_+_20720808 8.13 ENSDART00000171321
si:dkey-211f22.5
si:dkey-211f22.5
chr25_+_25124684 6.05 ENSDART00000167542
ldha
lactate dehydrogenase A4
chr25_-_28674739 5.29 ENSDART00000067073
lrrc10
leucine rich repeat containing 10
chr3_+_24207243 5.22 ENSDART00000023454
ENSDART00000136400
adsl
adenylosuccinate lyase
chr17_+_20605013 4.98 ENSDART00000156878
si:ch73-288o11.5
si:ch73-288o11.5
chr22_+_39096911 4.51 ENSDART00000157127
ENSDART00000153841
lmcd1
LIM and cysteine-rich domains 1
chr18_+_808911 4.28 ENSDART00000172518
cox5ab
cytochrome c oxidase subunit Vab
chr7_+_48555400 3.91 ENSDART00000174474
kcnq1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr13_+_27040887 3.40 ENSDART00000132714
soul2
heme-binding protein soul2
chr3_-_31019715 3.24 ENSDART00000156687
ENSDART00000156127
ENSDART00000153945
si:dkeyp-71f10.5
si:dkeyp-71f10.5
chr19_+_7292654 2.92 ENSDART00000140459
ccdc127b
coiled-coil domain containing 127b
chr23_-_33558161 2.87 ENSDART00000018301
itga5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr7_+_48555626 2.86 ENSDART00000125483
ENSDART00000083514
kcnq1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr6_-_39051319 2.49 ENSDART00000155093
tns2b
tensin 2b
chr6_-_46875310 2.33 ENSDART00000154442
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr6_+_38880166 2.31 ENSDART00000019939
ENSDART00000144286
bin2b
bridging integrator 2b
chr7_+_34602991 2.17 ENSDART00000073447
fhod1
formin homology 2 domain containing 1
chrM_+_10590 1.98 ENSDART00000093615
mt-nd3
NADH dehydrogenase 3, mitochondrial
chr2_-_8609653 1.89 ENSDART00000193354
ENSDART00000189489
ENSDART00000186144
si:ch211-71m22.1
si:ch211-71m22.1
chr19_+_7292445 1.89 ENSDART00000026634
ccdc127b
coiled-coil domain containing 127b
chr4_-_67799941 1.88 ENSDART00000185830
si:ch211-66c13.1
si:ch211-66c13.1
chr6_+_38879961 1.82 ENSDART00000184798
bin2b
bridging integrator 2b
chr2_+_26237322 1.81 ENSDART00000030520
palm1b
paralemmin 1b
chr11_-_24063196 1.75 ENSDART00000036513
trib3
tribbles pseudokinase 3
chr22_-_24248420 1.73 ENSDART00000165433
rgs2
regulator of G protein signaling 2
chr12_-_19862912 1.71 ENSDART00000145788
shisa9a
shisa family member 9a
chr5_-_54712159 1.60 ENSDART00000149207
ccnb1
cyclin B1
chr7_-_30639385 1.53 ENSDART00000173618
myo1ea
myosin IE, a
chr22_+_38762693 1.49 ENSDART00000015016
ENSDART00000150187
alpi.1
alkaline phosphatase, intestinal, tandem duplicate 1
chr12_-_30583668 1.46 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr6_+_52931841 1.45 ENSDART00000174358
si:dkeyp-3f10.12
si:dkeyp-3f10.12
chr8_+_52642869 1.42 ENSDART00000163617
ENSDART00000189997
si:dkey-90l8.3
si:dkey-90l8.3
chr19_-_24224142 1.42 ENSDART00000136409
ENSDART00000114390
prf1.8
perforin 1.8
chr2_-_36494308 1.35 ENSDART00000110378
BX901889.2

chr1_+_55662491 1.34 ENSDART00000152386
adgre8
adhesion G protein-coupled receptor E8
chr1_+_55583116 1.29 ENSDART00000152163
adgre19
adhesion G protein-coupled receptor E19
chr11_-_36040549 1.26 ENSDART00000112684
setmar
SET domain and mariner transposase fusion gene
chr2_+_26240339 1.23 ENSDART00000191006
palm1b
paralemmin 1b
chr12_+_34953038 1.23 ENSDART00000187022
ENSDART00000123988
ENSDART00000027034
qki2
QKI, KH domain containing, RNA binding 2
chr1_-_58000438 1.22 ENSDART00000163761
si:ch211-114l13.9
si:ch211-114l13.9
chr8_-_36469117 1.13 ENSDART00000111240
mhc2dab
major histocompatibility complex class II DAB gene
chr13_+_25412307 1.10 ENSDART00000175339
calhm1
calcium homeostasis modulator 1
chr8_-_20243389 0.98 ENSDART00000184904
acer1
alkaline ceramidase 1
chr22_+_8753092 0.98 ENSDART00000140720
si:dkey-182g1.2
si:dkey-182g1.2
chr3_+_22335030 0.97 ENSDART00000055676
zgc:103564
zgc:103564
chr22_-_10586191 0.94 ENSDART00000148418
si:dkey-42i9.16
si:dkey-42i9.16
chr7_+_16991711 0.88 ENSDART00000173660
nav2a
neuron navigator 2a
chr4_-_3805992 0.83 ENSDART00000190125
si:dkey-61f9.1
si:dkey-61f9.1
chr21_+_34088377 0.83 ENSDART00000170070
mtmr1b
myotubularin related protein 1b
chr15_-_31357634 0.82 ENSDART00000127485
or111-2
odorant receptor, family D, subfamily 111, member 2
chr8_-_44299247 0.80 ENSDART00000144497
piwil1
piwi-like RNA-mediated gene silencing 1
chr7_-_24875421 0.78 ENSDART00000173920
adad2
adenosine deaminase domain containing 2
chr7_+_48675347 0.75 ENSDART00000157917
ENSDART00000185580
trpm5
transient receptor potential cation channel, subfamily M, member 5
chr2_+_19195841 0.70 ENSDART00000163137
ENSDART00000161095
elovl1a
ELOVL fatty acid elongase 1a
chr11_-_308838 0.70 ENSDART00000112538
poc1a
POC1 centriolar protein A
chr3_+_17933553 0.70 ENSDART00000167731
ENSDART00000165644
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr21_-_2348838 0.69 ENSDART00000160337
si:ch73-299h12.8
si:ch73-299h12.8
chr13_-_36579086 0.69 ENSDART00000146671
lgals3a
lectin, galactoside binding soluble 3a
chr13_+_10023256 0.67 ENSDART00000110035
srbd1
S1 RNA binding domain 1
chr7_+_24390939 0.65 ENSDART00000087494
ENSDART00000125463
haus3
HAUS augmin-like complex, subunit 3
chr11_-_8271374 0.62 ENSDART00000168253
pimr202
Pim proto-oncogene, serine/threonine kinase, related 202
chr9_+_7724152 0.61 ENSDART00000061716
mnx2a
motor neuron and pancreas homeobox 2a
chr22_+_28818291 0.60 ENSDART00000136032
tp53bp2b
tumor protein p53 binding protein, 2b
chr25_+_19485198 0.60 ENSDART00000156730
glsl
glutaminase like
chr16_+_5539189 0.59 ENSDART00000178106
CR848788.2

chr5_-_35456269 0.58 ENSDART00000051312
ttc33
tetratricopeptide repeat domain 33
chr2_-_59345920 0.57 ENSDART00000134662
ftr37
finTRIM family, member 37
chr1_-_43862638 0.56 ENSDART00000145044
tacr3a
tachykinin receptor 3a
chr11_-_8226088 0.55 ENSDART00000173364
si:cabz01021067.1
si:cabz01021067.1
chr7_+_42461850 0.53 ENSDART00000190350
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr8_-_44298964 0.48 ENSDART00000098520
fzd10
frizzled class receptor 10
chr24_+_39576071 0.48 ENSDART00000147137
si:dkey-161j23.6
si:dkey-161j23.6
chr7_+_25053331 0.46 ENSDART00000173998
si:dkey-23i12.7
si:dkey-23i12.7
chr1_+_46026457 0.45 ENSDART00000132705
si:ch211-138g9.2
si:ch211-138g9.2
chr2_-_52020049 0.43 ENSDART00000128198
ENSDART00000135331
scn12aa
sodium channel, voltage gated, type XII, alpha a
chr12_+_20506197 0.43 ENSDART00000153010
si:zfos-754c12.2
si:zfos-754c12.2
chr9_-_7089303 0.39 ENSDART00000146609
coa5
cytochrome C oxidase assembly factor 5
chr15_-_23508214 0.33 ENSDART00000115051
abcg4b
ATP-binding cassette, sub-family G (WHITE), member 4b
chr11_+_583725 0.31 ENSDART00000189415
mkrn2os.2
MKRN2 opposite strand, tandem duplicate 2
chr4_+_76748500 0.30 ENSDART00000075607
ms4a17a.10
membrane-spanning 4-domains, subfamily A, member 17A.10
chr18_-_22701800 0.27 ENSDART00000135098
si:ch73-113g13.3
si:ch73-113g13.3
chr7_+_1442059 0.25 ENSDART00000173391
si:cabz01090193.1
si:cabz01090193.1
chr12_-_23009312 0.24 ENSDART00000111801
mkxa
mohawk homeobox a
chr18_+_45504362 0.24 ENSDART00000140089
cngb1a
cyclic nucleotide gated channel beta 1a
chr8_-_4100365 0.23 ENSDART00000142846
cux2b
cut-like homeobox 2b
chr21_+_45502621 0.21 ENSDART00000166719
si:dkey-223p19.2
si:dkey-223p19.2
chr11_-_1956204 0.21 ENSDART00000185541
nr1d4b
nuclear receptor subfamily 1, group D, member 4b
chr7_-_48733662 0.20 ENSDART00000191675
traf6
TNF receptor-associated factor 6
chr4_-_17838179 0.20 ENSDART00000146931
avpr2l
arginine vasopressin receptor 2, like
chr4_-_20314749 0.19 ENSDART00000066894
ENSDART00000188123
dcp1b
decapping mRNA 1B
chr7_-_3894831 0.18 ENSDART00000172921
si:dkey-88n24.11
si:dkey-88n24.11
chr15_-_23482088 0.18 ENSDART00000185823
ENSDART00000185523
nlrx1
NLR family member X1
chr4_-_75812937 0.18 ENSDART00000125096
si:ch211-203c5.3
si:ch211-203c5.3
chr5_-_64511428 0.16 ENSDART00000016321
rxrab
retinoid x receptor, alpha b
chr3_+_17933132 0.13 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr22_-_5724085 0.12 ENSDART00000110526
ENSDART00000140905
pgbd4
piggyBac transposable element derived 4
chr10_-_16062565 0.11 ENSDART00000188728
si:dkey-184a18.5
si:dkey-184a18.5
chr11_-_5939861 0.11 ENSDART00000110033
abhd8b
abhydrolase domain containing 8b
chr13_+_46927350 0.09 ENSDART00000165041
ENSDART00000167931
mtrf1l
mitochondrial translational release factor 1-like
chr20_+_46255057 0.08 ENSDART00000100536
taar14i
trace amine associated receptor 14i
chr15_-_434503 0.06 ENSDART00000122286
CABZ01056629.1

chr15_-_4053149 0.05 ENSDART00000189076
CR626884.4

chr1_+_57040472 0.04 ENSDART00000181365
si:ch211-1f22.16
si:ch211-1f22.16
chr11_+_12879635 0.02 ENSDART00000182515
ENSDART00000081296
si:dkey-11m19.5
si:dkey-11m19.5
chr14_-_11507211 0.02 ENSDART00000186873
ENSDART00000109181
ENSDART00000186166
ENSDART00000186986
zgc:174917
zgc:174917

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 24.3 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.7 4.1 GO:0071800 podosome assembly(GO:0071800)
0.6 5.2 GO:0006167 AMP biosynthetic process(GO:0006167)
0.5 2.9 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.4 1.7 GO:0090299 regulation of neural crest formation(GO:0090299)
0.4 5.3 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.3 9.6 GO:0001757 somite specification(GO:0001757)
0.3 4.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.7 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.8 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 2.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.0 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.3 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 0.6 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 0.6 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 1.5 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 0.8 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.8 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 1.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 6.0 GO:0001666 response to hypoxia(GO:0001666)
0.1 0.6 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.7 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 1.7 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 1.1 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.8 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 3.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.3 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.2 GO:0045445 myoblast differentiation(GO:0045445)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.1 GO:0001891 phagocytic cup(GO:0001891)
0.5 1.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.3 4.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 11.1 GO:0016459 myosin complex(GO:0016459)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 0.6 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.9 GO:0008305 integrin complex(GO:0008305)
0.0 2.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0043186 P granule(GO:0043186)
0.0 4.8 GO:0030017 sarcomere(GO:0030017)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 19.8 GO:0005739 mitochondrion(GO:0005739)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 24.3 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.3 5.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.9 6.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.6 1.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.3 0.8 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 1.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 1.0 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 4.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.7 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 2.9 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.8 GO:0034584 piRNA binding(GO:0034584)
0.1 1.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 11.2 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.7 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 3.4 GO:0020037 heme binding(GO:0020037)
0.0 7.5 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 6.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 1.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 6.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 6.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)