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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nkx2.2b

Z-value: 0.61

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Transcription factors associated with nkx2.2b

Gene Symbol Gene ID Gene Info
ENSDARG00000101549 NK2 homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.2bdr11_v1_chr20_+_48782068_48782068-0.414.7e-05Click!

Activity profile of nkx2.2b motif

Sorted Z-values of nkx2.2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_8840772 3.87 ENSDART00000059321
epithelial cell adhesion molecule
chr9_-_33063083 3.20 ENSDART00000048550
si:ch211-125e6.5
chr3_-_27647845 3.09 ENSDART00000151625
si:ch211-157c3.4
chr3_-_49110710 3.05 ENSDART00000160404
tripartite motif containing 35-12
chr16_+_29586004 3.05 ENSDART00000149520
MCL1, BCL2 family apoptosis regulator b
chr24_-_30263301 3.02 ENSDART00000162328
sorting nexin 7
chr11_-_30636163 3.00 ENSDART00000140516
zgc:153665
chr15_-_20468302 2.78 ENSDART00000018514
deltaC
chr19_+_9344171 2.73 ENSDART00000133447
ENSDART00000104622
si:ch211-288g17.4
chr5_-_38777852 2.73 ENSDART00000131603
si:dkey-58f10.4
chr22_+_11775269 2.72 ENSDART00000140272
keratin 96
chr7_-_16562200 2.59 ENSDART00000169093
ENSDART00000173491
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr4_-_25215968 2.58 ENSDART00000066932
ENSDART00000066933
inter-alpha-trypsin inhibitor heavy chain 2
chr15_+_13984879 2.56 ENSDART00000159438
zgc:162730
chr2_-_28396993 2.55 ENSDART00000188170

chr5_-_37117778 2.44 ENSDART00000149138
interleukin 13 receptor, alpha 2
chr2_-_51772438 2.44 ENSDART00000170241
Danio rerio three-finger protein 5 (LOC100003647), mRNA.
chr8_+_25302172 2.37 ENSDART00000046182
ENSDART00000145316
glutathione S-transferase mu tandem duplicate 3
chr16_+_23913943 2.34 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr7_-_22790630 2.29 ENSDART00000173496
si:ch211-15b10.6
chr5_+_1877464 2.28 ENSDART00000050658
zgc:101699
chr20_-_5267600 2.27 ENSDART00000099258
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4
chr7_+_35268054 2.26 ENSDART00000113842
dipeptidase 2
chr12_-_48671612 2.22 ENSDART00000007202
zgc:92749
chr9_-_9998087 2.21 ENSDART00000124423
UDP glucuronosyltransferase 1 family a, b
chr8_-_38317914 2.20 ENSDART00000125920
PDZ and LIM domain 2 (mystique)
chr8_-_50482781 2.15 ENSDART00000056361
indoleamine 2,3-dioxygenase 1
chr1_+_17900306 2.12 ENSDART00000089480
cytochrome P450, family 4, subfamily V, polypeptide 8
chr25_+_10416583 2.10 ENSDART00000073907
ets homologous factor
chr22_-_17631675 2.09 ENSDART00000132565
histocompatibility (minor) HA-1 b
chr13_-_30996072 2.08 ENSDART00000181661
WDFY family member 4
chr20_-_28349144 2.07 ENSDART00000179690
ENSDART00000188059
INO80 complex subunit
chr12_-_30558694 2.03 ENSDART00000153417
si:ch211-28p3.3
chr4_+_2230701 2.03 ENSDART00000080439
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr12_-_22400999 2.02 ENSDART00000153194
si:dkey-38p12.3
chr2_+_48282590 2.01 ENSDART00000035338
lysophosphatidic acid receptor 5a
chr9_+_41156287 2.01 ENSDART00000189195
ENSDART00000186270
signal transducer and activator of transcription 4
chr2_+_1487118 1.95 ENSDART00000147283
complement component 8, alpha polypeptide
chr2_+_26498446 1.94 ENSDART00000078412
ribosomal protein S8a
chr18_-_7631301 1.92 ENSDART00000062166
tripartite motif containing 35-30
chr11_+_31285127 1.91 ENSDART00000160154
si:dkey-238i5.2
chr22_+_21317597 1.88 ENSDART00000132605
SHC (Src homology 2 domain containing) transforming protein 2
chr14_+_26759332 1.88 ENSDART00000088484
AHNAK nucleoprotein
chr9_-_18911608 1.84 ENSDART00000138785
si:dkey-239h2.3
chr23_-_39784368 1.83 ENSDART00000110282
si:ch211-286f9.2
chr5_-_37900350 1.80 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
transmembrane protease, serine 13b
chr23_+_1078072 1.79 ENSDART00000159263
ENSDART00000053527
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2b
chr19_-_24555935 1.78 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr13_-_40401870 1.76 ENSDART00000128951
NK3 homeobox 3
chr2_-_37956768 1.76 ENSDART00000034595
cerebellin 10
chr23_+_38245610 1.74 ENSDART00000191386
zinc finger protein 217
chr14_+_1170968 1.73 ENSDART00000125203
ENSDART00000193575
HOP homeobox
chr23_-_24394719 1.71 ENSDART00000044918
eph receptor A2 b
chr7_+_12950507 1.71 ENSDART00000067629
ENSDART00000158004
serum amyloid A
chr7_-_26518086 1.69 ENSDART00000058913
eukaryotic translation initiation factor 4A1A
chr2_+_1486822 1.69 ENSDART00000132500
complement component 8, alpha polypeptide
chr11_+_14286160 1.69 ENSDART00000166236
si:ch211-262i1.3
chr2_+_36114194 1.67 ENSDART00000113547
T-cell receptor alpha joining 39
chr7_+_50849142 1.67 ENSDART00000073806
procollagen C-endopeptidase enhancer b
chr13_-_22699024 1.64 ENSDART00000016946
glutamate dehydrogenase 1a
chr1_+_52560549 1.64 ENSDART00000167514
ATP-binding cassette, sub-family A (ABC1), member 1A
chr13_-_40237121 1.63 ENSDART00000145635
lysyl oxidase-like 4
chr1_-_47122058 1.63 ENSDART00000159925
ENSDART00000101143
ENSDART00000176803
major histocompatibility complex class I ZEA
chr2_+_36121373 1.62 ENSDART00000187002

chr8_+_1170015 1.61 ENSDART00000081457
ENSDART00000164116
chemokine (C-C motif) ligand 27a
chr4_-_9891874 1.61 ENSDART00000067193
adrenomedullin 2a
chr7_-_38087865 1.61 ENSDART00000052366
CCAAT/enhancer binding protein (C/EBP), alpha
chr1_-_43905252 1.58 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr23_+_36653376 1.58 ENSDART00000053189
G protein-coupled receptor 182
chr19_-_24555623 1.58 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr22_+_883678 1.57 ENSDART00000140588
serine/threonine kinase 38b
chr1_-_354115 1.57 ENSDART00000141590
ENSDART00000098627
protein S
chr23_+_20803270 1.56 ENSDART00000097381
zgc:154075
chr7_+_21275152 1.56 ENSDART00000173612
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr13_-_25819825 1.55 ENSDART00000077612
v-rel avian reticuloendotheliosis viral oncogene homolog
chr8_-_45760087 1.55 ENSDART00000025620
peptidylprolyl isomerase Aa (cyclophilin A)
chr14_+_23717165 1.54 ENSDART00000006373
Nedd4 family interacting protein 1
chr18_+_37272568 1.52 ENSDART00000132749
transmembrane protein 123
chr3_+_4403980 1.46 ENSDART00000156881

chr21_+_33454147 1.45 ENSDART00000053208
ribosomal protein S14
chr2_-_24269911 1.45 ENSDART00000099532
myosin heavy chain 7
chr1_+_36651059 1.44 ENSDART00000187475
endothelin receptor type Aa
chr1_+_1915967 1.43 ENSDART00000131463
si:ch211-132g1.1
chr12_-_28794957 1.42 ENSDART00000020667
oxysterol binding protein-like 7
chr19_-_48330287 1.42 ENSDART00000162244
si:ch73-359m17.7
chr24_+_38205798 1.40 ENSDART00000141532
immunoglobulin light 3 variable 1
chr15_-_1198886 1.40 ENSDART00000063285
latexin
chr17_+_6538733 1.40 ENSDART00000193712
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr12_-_30548244 1.40 ENSDART00000193616
zgc:158404
chr7_+_32901658 1.39 ENSDART00000115420
anoctamin 9b
chr6_+_11438972 1.36 ENSDART00000029314
collagen, type V, alpha 2b
chr4_+_6032640 1.31 ENSDART00000157487
transcription factor EC
chr4_-_22311610 1.31 ENSDART00000137814
hematopoietic cell-specific Lyn substrate 1
chr1_+_8534698 1.29 ENSDART00000021504
Smith-Magenis syndrome chromosome region, candidate 8b
chr22_-_7539414 1.29 ENSDART00000159083

chr20_+_33904258 1.28 ENSDART00000170930
retinoid X receptor, gamma b
chr3_+_19216567 1.27 ENSDART00000134433
interleukin 12 receptor, beta 2a, like
chr13_+_44857087 1.24 ENSDART00000017770
zinc finger and BTB domain containing 8 opposite strand
chr9_+_18023288 1.24 ENSDART00000098355
TNF superfamily member 11
chr14_-_25956804 1.23 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
secreted protein, acidic, cysteine-rich (osteonectin)
chr24_-_33308045 1.23 ENSDART00000149711
solute carrier family 4 (anion exchanger), member 2b
chr6_-_54107269 1.22 ENSDART00000190017
hyaluronoglucosaminidase 2a
chr2_+_2967255 1.22 ENSDART00000167649
ENSDART00000166449
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr5_+_26795773 1.21 ENSDART00000145631
transcobalamin II
chr20_-_32045057 1.21 ENSDART00000152970
ENSDART00000034248
RAB32a, member RAS oncogene family
chr11_-_25257595 1.21 ENSDART00000123567
snail family zinc finger 1a
chr16_+_23087326 1.20 ENSDART00000167518
ENSDART00000161087
ephrin-A3b
chr4_+_58576146 1.17 ENSDART00000164911
si:ch211-212k5.4
chr23_+_35847538 1.16 ENSDART00000143935
retinoic acid receptor gamma a
chr21_+_25793970 1.14 ENSDART00000101217
zgc:136892
chr6_-_41085443 1.13 ENSDART00000143944
ENSDART00000028217
serine/arginine-rich splicing factor 3a
chr18_-_50152689 1.13 ENSDART00000006078
lysyl oxidase-like 1
chr8_-_38105053 1.12 ENSDART00000131546
adhesion G protein-coupled receptor A2
chr15_+_37589698 1.12 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin-37 DREAM MuvB core complex component
chr24_+_38197852 1.12 ENSDART00000142949
immunoglobulin light 3 variable 4
chr8_-_43847138 1.12 ENSDART00000148358
adhesion G protein-coupled receptor D1
chr22_-_6941098 1.11 ENSDART00000105864
zgc:171500
chr2_-_58183499 1.10 ENSDART00000172281
ENSDART00000186262
si:ch1073-185p12.2
chr7_+_57108823 1.10 ENSDART00000184943
ENSDART00000055956
enolase superfamily member 1
chr16_-_51288178 1.09 ENSDART00000079864
zgc:173729
chr21_-_36619599 1.09 ENSDART00000065208
NOP16 nucleolar protein homolog (yeast)
chr11_+_3308656 1.09 ENSDART00000082458
SAP domain containing ribonucleoprotein
chr21_+_19547806 1.07 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
retinoic acid induced 14
chr17_+_20616196 1.07 ENSDART00000153515
si:ch73-306e8.2
chr16_-_33105677 1.07 ENSDART00000145055
proline-rich nuclear receptor coactivator 2
chr7_-_8309505 1.06 ENSDART00000182530
coagulation factor XIII, A1 polypeptide b
chr4_-_16644708 1.06 ENSDART00000042307
SIN3-HDAC complex associated factor
chr6_-_41079209 1.06 ENSDART00000151592
RAB44, member RAS oncogene family
chr14_-_38873095 1.05 ENSDART00000047050
ENSDART00000173285
ENSDART00000147521
glutathione reductase
chr2_-_36494308 1.04 ENSDART00000110378

chr5_+_43782267 1.04 ENSDART00000130355
nitric oxide synthase 2a, inducible
chr3_-_11008532 1.03 ENSDART00000165086

chr25_+_4635355 1.03 ENSDART00000021120
protein-glucosylgalactosylhydroxylysine glucosidase
chr4_-_68901741 1.02 ENSDART00000163087
si:dkey-264f17.5
chr3_+_60761811 1.01 ENSDART00000053482
TSEN54 tRNA splicing endonuclease subunit
chr20_-_39333657 1.00 ENSDART00000153720
ENSDART00000142164
chemokine (C-C motif) ligand 38, duplicate 1
chr4_+_62184754 1.00 ENSDART00000168844
si:dkeyp-35e5.9
chr23_-_27701361 0.99 ENSDART00000186688
ENSDART00000183985
DnaJ (Hsp40) homolog, subfamily C, member 22
chr23_+_19813677 0.99 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr19_+_4066449 0.99 ENSDART00000162461
bloodthirsty-related gene family, member 26
chr1_+_55703120 0.97 ENSDART00000141089
adhesion G protein-coupled receptor E6
chr5_+_3927989 0.95 ENSDART00000030125
zinc finger, HIT-type containing 3
chr23_-_40295610 0.95 ENSDART00000186719

chr9_+_1313418 0.95 ENSDART00000191361
caspase 8, apoptosis-related cysteine peptidase, like 2
chr19_-_808265 0.93 ENSDART00000082454
glycosylated lysosomal membrane protein
chr2_-_51757328 0.93 ENSDART00000189286
si:ch211-9d9.1
chr4_-_7673165 0.93 ENSDART00000028171
leukotriene A4 hydrolase
chr3_-_16110100 0.92 ENSDART00000051807
LIM and SH3 protein 1
chr12_+_33320884 0.92 ENSDART00000188988
casein kinase 1, delta b
chr24_-_26484298 0.92 ENSDART00000140647
eukaryotic translation initiation factor 5A
chr9_+_40546677 0.92 ENSDART00000132911
von Willebrand factor C domain containing protein 2-like
chr3_+_16841942 0.91 ENSDART00000023985
ENSDART00000145317
serine/threonine kinase 17a like
chr1_+_55723870 0.90 ENSDART00000146614
adhesion G protein-coupled receptor E17
chr2_-_7696287 0.90 ENSDART00000190769

chr6_-_26895314 0.90 ENSDART00000134259
high density lipoprotein binding protein a
chr2_-_1514001 0.90 ENSDART00000057736
complement component 8, beta polypeptide
chr16_+_35887868 0.90 ENSDART00000169677
ENSDART00000170772
thyroid hormone receptor associated protein 3a
chr18_+_40471826 0.89 ENSDART00000098806
UDP glucuronosyltransferase 5 family, polypeptide C3
chr11_+_37638873 0.89 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
SH2 domain containing 5
chr25_+_15994100 0.88 ENSDART00000144723
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr4_-_75552652 0.88 ENSDART00000169253
ENSDART00000182360
si:dkey-71l4.4
si:dkey-71l4.5
chr20_-_34750045 0.87 ENSDART00000186130
zinc finger protein 395b
chr6_+_49255706 0.87 ENSDART00000156866
si:dkey-183k8.2
chr14_-_733565 0.86 ENSDART00000158097
toll-like receptor 1
chr24_+_5935377 0.86 ENSDART00000191989
ENSDART00000185932
ENSDART00000131768
abl-interactor 1a
chr10_-_22117121 0.86 ENSDART00000149470
si:ch73-111e15.1
chr21_-_40835069 0.86 ENSDART00000004686
LIM domain kinase 1b
chr19_-_24745317 0.85 ENSDART00000142774
si:dkeyp-92c9.3
chr20_+_53577502 0.85 ENSDART00000126983
myosin, heavy chain 6, cardiac muscle, alpha
chr13_-_48058779 0.85 ENSDART00000186623
ENSDART00000045475
integrin, alpha 9
chr21_-_37733571 0.85 ENSDART00000176214
membrane protein, palmitoylated 1
chr20_+_9128256 0.84 ENSDART00000163883
ENSDART00000183072
ENSDART00000187276
bisphosphate nucleotidase 1
chr2_-_37280617 0.84 ENSDART00000190458
NAD kinase b
chr19_-_3255725 0.83 ENSDART00000105165
immune-related, lectin-like receptor 1
chr1_-_49558223 0.83 ENSDART00000138510
si:ch211-281g13.4
chr3_-_5413018 0.82 ENSDART00000063138
vitelline membrane outer layer 1 homolog a
chr12_+_33484458 0.81 ENSDART00000000069
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a
chr22_+_19453822 0.81 ENSDART00000141371
si:dkey-78l4.6
chr17_+_20616576 0.78 ENSDART00000153561
si:ch73-306e8.2
chr11_+_14284866 0.78 ENSDART00000163729
si:ch211-262i1.3
chr3_-_34107685 0.77 ENSDART00000151130
immunoglobulin heavy variable 4-3
chr2_-_10877228 0.77 ENSDART00000138718
ENSDART00000034246
cell division cycle 7 homolog (S. cerevisiae)
chr21_-_14310159 0.77 ENSDART00000155097
si:ch211-196i2.1
chr13_-_43238578 0.76 ENSDART00000161017
eukaryotic translation initiation factor 3, subunit 6 interacting protein
chr12_+_6002715 0.76 ENSDART00000114961
si:ch211-131k2.3
chr6_+_13201358 0.76 ENSDART00000190290

chr6_+_27923054 0.75 ENSDART00000136833
ENSDART00000145533
centrosomal protein 63
chr14_-_46173265 0.75 ENSDART00000164321
zmp:0000000758
chr23_+_25354856 0.75 ENSDART00000109023
ENSDART00000147440
formin-like 3
chr16_-_22585289 0.74 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cingulin a
chr8_+_26292560 0.74 ENSDART00000053463
monoglyceride lipase
chr8_-_25728628 0.74 ENSDART00000127237
forkhead box P3a
chr19_+_30867845 0.74 ENSDART00000047461
major facilitator superfamily domain containing 2ab
chr2_+_11028923 0.73 ENSDART00000076725
acyl-CoA thioesterase 11a
chr24_+_24726956 0.73 ENSDART00000144574
ENSDART00000066628
mitochondrial fission regulator 1
chr19_+_40861853 0.72 ENSDART00000126470
zgc:85777
chr5_+_42141917 0.72 ENSDART00000172201
ENSDART00000140743
transient receptor potential cation channel, subfamily V, member 1
chr16_+_3185541 0.72 ENSDART00000024088
WD repeat domain 21
chr7_-_17627320 0.71 ENSDART00000101701
novel immune-type receptor 6a
chr23_-_4925641 0.71 ENSDART00000140861
ENSDART00000060718
tafazzin

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.6 2.6 GO:0035994 response to muscle stretch(GO:0035994)
0.5 1.6 GO:0042730 fibrinolysis(GO:0042730)
0.4 2.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.4 1.6 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.4 1.2 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.4 1.2 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.4 2.8 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.4 1.1 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.3 1.4 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3 1.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3 1.9 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.3 2.0 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 1.7 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.3 2.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.3 1.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.3 1.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 1.4 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2 1.6 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.2 2.3 GO:0006706 steroid catabolic process(GO:0006706) cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 0.6 GO:0001562 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.2 3.0 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.2 2.0 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 0.6 GO:0005991 trehalose metabolic process(GO:0005991)
0.2 3.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 0.6 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.2 0.9 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.2 0.5 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 1.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 1.0 GO:0031284 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.2 0.8 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.2 4.5 GO:0019835 cytolysis(GO:0019835)
0.2 2.8 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 0.8 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.7 GO:0045056 transcytosis(GO:0045056)
0.1 1.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 1.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.2 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.9 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0007414 axonal defasciculation(GO:0007414)
0.1 1.8 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.4 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.5 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 3.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 2.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.6 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 3.9 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.1 0.9 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.1 2.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.2 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 3.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 0.4 GO:0042117 monocyte activation(GO:0042117)
0.1 1.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 3.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.6 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 2.5 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.5 GO:0006203 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 1.2 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 1.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.7 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.1 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 2.4 GO:0060037 pharyngeal system development(GO:0060037)
0.1 1.6 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 1.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.5 GO:0003139 secondary heart field specification(GO:0003139)
0.0 1.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 1.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 1.0 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.0 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 2.7 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.8 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.7 GO:0009408 response to heat(GO:0009408)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 2.3 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.1 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 4.8 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 1.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.8 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.5 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 1.5 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 0.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 1.1 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.8 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.7 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 1.3 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 1.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.6 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.4 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 1.9 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 1.3 GO:0006364 rRNA processing(GO:0006364)
0.0 1.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 2.7 GO:0008380 RNA splicing(GO:0008380)
0.0 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 1.1 GO:0016052 carbohydrate catabolic process(GO:0016052)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0043034 costamere(GO:0043034)
0.3 1.4 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 4.5 GO:0005579 membrane attack complex(GO:0005579)
0.3 1.1 GO:1990909 Wnt signalosome(GO:1990909)
0.3 1.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 0.6 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 1.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 0.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 3.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.1 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.5 GO:0005903 brush border(GO:0005903)
0.1 3.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 3.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 2.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 4.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 1.7 GO:0030175 filopodium(GO:0030175)
0.0 3.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 7.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.1 GO:0016459 myosin complex(GO:0016459)
0.0 1.3 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.0 GO:0008305 integrin complex(GO:0008305)
0.0 2.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.5 GO:0030018 Z disc(GO:0030018)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.6 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.9 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.8 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.7 2.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.5 2.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.4 2.3 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.3 1.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 1.6 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 0.9 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.3 1.5 GO:0050699 WW domain binding(GO:0050699)
0.3 1.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.3 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 1.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 1.0 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.2 1.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 2.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.2 0.6 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.2 0.6 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.2 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 4.8 GO:0042805 actinin binding(GO:0042805)
0.2 2.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 3.0 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 1.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 0.3 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 2.8 GO:0005112 Notch binding(GO:0005112)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 2.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.6 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 1.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.5 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.1 0.3 GO:0004312 fatty acid synthase activity(GO:0004312)
0.1 0.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.6 GO:0004096 catalase activity(GO:0004096)
0.1 2.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 1.9 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.1 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.4 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.3 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.1 GO:0015926 glucosidase activity(GO:0015926)
0.0 5.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 2.6 GO:0008009 chemokine activity(GO:0008009)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 4.8 GO:0019955 cytokine binding(GO:0019955)
0.0 1.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.8 GO:0008252 nucleotidase activity(GO:0008252)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 3.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 3.4 GO:0003774 motor activity(GO:0003774)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 1.6 GO:0046906 tetrapyrrole binding(GO:0046906)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 1.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 5.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 4.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 2.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions