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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nr2c2

Z-value: 0.77

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Transcription factors associated with nr2c2

Gene Symbol Gene ID Gene Info
ENSDARG00000042477 nuclear receptor subfamily 2, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2c2dr11_v1_chr8_+_53120278_53120278-0.331.3e-03Click!

Activity profile of nr2c2 motif

Sorted Z-values of nr2c2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_36837846 19.08 ENSDART00000032481
creatine kinase, muscle a
chr3_+_39566999 14.76 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr2_+_42191592 11.96 ENSDART00000144716
caveolae associated protein 4a
chr18_+_1615 10.82 ENSDART00000082450
homer scaffolding protein 2
chr20_+_15015557 10.76 ENSDART00000039345
myocilin
chr11_+_11201096 10.46 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr21_-_19006631 10.15 ENSDART00000080269
ENSDART00000191682
phosphoglycerate mutase 2 (muscle)
chr9_-_22834860 9.86 ENSDART00000146486
nebulin
chr3_+_30257582 9.03 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
myosin binding protein C, fast type a
chr22_-_7050 8.75 ENSDART00000127829
ATPase family, AAA domain containing 3
chr7_+_31871830 8.40 ENSDART00000139899
myosin binding protein C, cardiac
chr12_-_4683325 7.86 ENSDART00000152771
si:ch211-255p10.3
chr11_+_77526 7.34 ENSDART00000193521

chr3_-_12187245 7.08 ENSDART00000189553
ENSDART00000165131
sarcalumenin
chr4_-_858434 6.95 ENSDART00000006961
sine oculis binding protein homolog (Drosophila) b
chr6_-_40722480 6.94 ENSDART00000188187
kelch repeat and BTB (POZ) domain containing 12
chr7_+_31838320 6.84 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
myosin binding protein C, cardiac
chr6_-_40722200 6.30 ENSDART00000035101
kelch repeat and BTB (POZ) domain containing 12
chr16_-_24612871 5.95 ENSDART00000155614
ENSDART00000154787
ENSDART00000155983
ENSDART00000156519
FXYD domain containing ion transport regulator 6 like
chr24_-_33703504 5.12 ENSDART00000079292
caveolae associated protein 4b
chr1_+_58353661 4.89 ENSDART00000140074
si:dkey-222h21.2
chr10_+_43994471 4.53 ENSDART00000138242
ENSDART00000186359
claudin 5b
chr19_-_9648542 4.47 ENSDART00000172628
chloride channel, voltage-sensitive 1a
chr15_-_29598679 4.31 ENSDART00000155153
si:ch211-207n23.2
chr6_+_27339962 4.11 ENSDART00000193726
kelch-like family member 30
chr18_-_48508585 4.11 ENSDART00000133364
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr21_-_35832548 4.01 ENSDART00000180840
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr16_-_19568388 3.99 ENSDART00000141616
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr1_-_58868306 3.89 ENSDART00000166615
dynamin 2b
chr2_+_57801960 3.81 ENSDART00000147966
si:dkeyp-68b7.10
chr18_-_48517040 3.78 ENSDART00000143645
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr21_+_15704556 3.74 ENSDART00000024858
ENSDART00000146909
coiled-coil-helix-coiled-coil-helix domain containing 10
chr18_-_48492951 3.55 ENSDART00000146346
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr7_+_22718251 3.50 ENSDART00000027718
ENSDART00000143341
fragile X mental retardation, autosomal homolog 2
chr8_+_44549290 3.46 ENSDART00000160801
si:dkey-220o5.5
chr10_+_35417099 3.44 ENSDART00000063398
HERV-H LTR-associating 2a, tandem duplicate 1
chr23_+_2740741 3.43 ENSDART00000134938
zgc:114123
chr1_+_58182400 3.42 ENSDART00000144784
si:ch211-15j1.1
chr3_-_34561624 3.35 ENSDART00000129313
septin 9a
chr16_-_24605969 3.28 ENSDART00000163305
ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr1_-_59232267 3.21 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr16_-_25233515 3.20 ENSDART00000058943
zgc:110182
chr16_-_22713152 3.10 ENSDART00000140953
ENSDART00000143836
si:ch211-105c13.3
chr18_-_48550426 3.01 ENSDART00000145189
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr6_+_60036767 2.98 ENSDART00000155009
transglutaminase 8
chr3_+_58167288 2.87 ENSDART00000155874
ENSDART00000010395
ubiquinol-cytochrome c reductase core protein 2a
chr24_+_81527 2.80 ENSDART00000192139
reversion-inducing-cysteine-rich protein with kazal motifs
chr17_+_53424415 2.79 ENSDART00000157022
solute carrier family 9 member A1b
chr17_+_15788100 2.73 ENSDART00000027667
ras-related GTP binding D
chr9_+_54644626 2.66 ENSDART00000190609
EGF-like-domain, multiple 6
chr14_+_97017 2.62 ENSDART00000159300
ENSDART00000169523
minichromosome maintenance complex component 7
chr21_-_1640547 2.60 ENSDART00000151041
zgc:152948
chr3_-_32590164 2.56 ENSDART00000151151
tetraspanin 4b
chr12_-_47782623 2.56 ENSDART00000115742
selenoprotein U1b
chr14_+_15331486 2.53 ENSDART00000172077
ENSDART00000183370
ENSDART00000182467
si:dkey-203a12.4
si:dkey-203a12.5
chr3_-_18410968 2.52 ENSDART00000041842
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
chr21_+_33454147 2.44 ENSDART00000053208
ribosomal protein S14
chr9_-_43082945 2.39 ENSDART00000142257
coiled-coil domain containing 141
chr5_+_35786141 2.39 ENSDART00000022043
ENSDART00000127383
StAR-related lipid transfer (START) domain containing 8
chr13_-_37254777 2.37 ENSDART00000139734
spectrin repeat containing, nuclear envelope 2b
chr12_+_46708920 2.37 ENSDART00000153089
exocyst complex component 7
chr4_-_16451375 2.36 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
chr7_+_34297271 2.34 ENSDART00000180342
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr21_-_308852 2.34 ENSDART00000151613
LHFPL tetraspan subfamily member 2a
chr23_+_42810055 2.29 ENSDART00000186647
myosin, light chain 9a, regulatory
chr19_+_2631565 2.29 ENSDART00000171487
family with sequence similarity 126, member A
chr3_+_301479 2.25 ENSDART00000165169

chr19_-_27564458 2.24 ENSDART00000123155
si:dkeyp-46h3.6
chr20_+_1996202 2.22 ENSDART00000184143

chr13_-_35808904 2.20 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr16_-_5115993 2.19 ENSDART00000138654
ttk protein kinase
chr17_-_8976307 2.18 ENSDART00000092113
zinc finger, RAN-binding domain containing 1b
chr5_+_22579975 2.14 ENSDART00000080877
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr1_+_15062 2.12 ENSDART00000169005
centrosomal protein 97
chr12_+_49125510 2.11 ENSDART00000185804

chr7_+_24115082 2.11 ENSDART00000182718
mitochondrial ribosomal protein L52
chr22_-_15587360 2.10 ENSDART00000142717
ENSDART00000138978
tropomyosin 4a
chr13_+_28819768 2.08 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653

chr8_+_31872992 2.08 ENSDART00000146933
complement component 7a
chr4_-_16833518 2.07 ENSDART00000179867
lactate dehydrogenase Ba
chr23_+_17865554 2.05 ENSDART00000181009
ENSDART00000162822
nascent polypeptide-associated complex alpha subunit
chr11_-_6974022 2.01 ENSDART00000172851
si:ch211-43f4.1
chr14_+_30413758 2.01 ENSDART00000092953
CCR4-NOT transcription complex, subunit 7
chr18_+_27926839 1.99 ENSDART00000191835
homeodomain interacting protein kinase 3b
chr7_-_2090594 1.99 ENSDART00000183166
si:cabz01007802.1
chr20_-_47953524 1.98 ENSDART00000167986
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr22_-_24992532 1.95 ENSDART00000102751
si:dkey-179j5.5
chr10_-_322769 1.94 ENSDART00000165244
v-akt murine thymoma viral oncogene homolog 2, like
chr23_-_16737161 1.89 ENSDART00000132573
si:ch211-224l10.4
chr7_+_24114694 1.89 ENSDART00000127177
mitochondrial ribosomal protein L52
chr22_-_28668442 1.87 ENSDART00000182377
collagen, type VIII, alpha 1b
chr8_-_50133064 1.87 ENSDART00000030064
anthrax toxin receptor 1a
chr3_+_1179601 1.86 ENSDART00000173378
TRIO and F-actin binding protein b
chr1_+_58312187 1.82 ENSDART00000142285
si:dkey-222h21.10
chr20_-_49117438 1.80 ENSDART00000057700
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr16_+_7985886 1.79 ENSDART00000126041
anoctamin 10a
chr1_+_45072778 1.78 ENSDART00000172529
bloodthirsty-related gene family, member 1
chr5_+_24282570 1.74 ENSDART00000041905
zinc finger, DHHC-type containing 23a
chr17_+_33418475 1.74 ENSDART00000169145
synaptosomal-associated protein 23.1
chr16_-_19568795 1.68 ENSDART00000185141
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr5_-_24124118 1.66 ENSDART00000051550
capping protein (actin filament), gelsolin-like a
chr1_-_44314 1.66 ENSDART00000160050
transmembrane protein 39A
chr6_-_49873020 1.66 ENSDART00000148511
GNAS complex locus
chr12_-_979789 1.63 ENSDART00000128188
diacylglycerol lipase, beta
chr1_-_52292235 1.60 ENSDART00000132638
si:dkey-121b10.7
chr17_+_53425037 1.59 ENSDART00000154983
fatty acid binding protein 10b, liver basic
chr6_+_52931841 1.59 ENSDART00000174358
si:dkeyp-3f10.12
chr6_+_1787160 1.58 ENSDART00000113505
myosin, light chain 9b, regulatory
chr25_+_418932 1.57 ENSDART00000059193
protogenin homolog b (Gallus gallus)
chr7_+_24520518 1.55 ENSDART00000173604
bloodthirsty-related gene family, member 9
chr8_+_2530065 1.54 ENSDART00000063943
mitochondrial ribosomal protein L40
chr1_+_58303892 1.53 ENSDART00000147678

chr1_+_58139102 1.53 ENSDART00000134826
si:ch211-15j1.4
chr17_-_22137199 1.52 ENSDART00000089689
mitochondrial ribosomal protein S5
chr3_-_36419641 1.51 ENSDART00000173545
component of oligomeric golgi complex 1
chr3_+_27770110 1.50 ENSDART00000017962
enoyl-CoA delta isomerase 1
chr1_+_57145072 1.49 ENSDART00000152776
si:ch73-94k4.4
chr25_+_31238606 1.48 ENSDART00000149439
troponin I type 2a (skeletal, fast), tandem duplicate 2
chr23_-_45504991 1.46 ENSDART00000148761
collagen type XXIV alpha 1
chr14_+_989733 1.45 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr23_+_8797143 1.44 ENSDART00000132992
SRY (sex determining region Y)-box 18
chr10_-_21362071 1.44 ENSDART00000125167
avidin
chr1_-_44933094 1.42 ENSDART00000147527
si:dkey-9i23.14
chr16_-_34258931 1.41 ENSDART00000145485
phosphatase and actin regulator 4b
chr1_-_51720633 1.40 ENSDART00000045894
ribonuclease H2, subunit A
chr21_-_9446747 1.38 ENSDART00000158790
protein tyrosine phosphatase, non-receptor type 13
chr3_-_18805225 1.38 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr25_+_20119466 1.38 ENSDART00000104304
2,3-bisphosphoglycerate mutase
chr16_-_54357200 1.38 ENSDART00000170753

chr8_+_50742975 1.38 ENSDART00000155664
ENSDART00000160612
si:ch73-6l19.2
chr7_+_34296789 1.38 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr14_+_34501245 1.36 ENSDART00000131424
lymphocyte cytosolic protein 2b
chr18_+_13315739 1.36 ENSDART00000143404
si:ch211-260p9.3
chr18_-_43866526 1.35 ENSDART00000111309
trehalase (brush-border membrane glycoprotein)
chr23_-_45705525 1.34 ENSDART00000148959
endothelin receptor type Ab
chr1_+_58119117 1.34 ENSDART00000146788
si:ch211-15j1.5
chr8_+_15251448 1.34 ENSDART00000063717
zgc:171480
chr20_+_47953047 1.32 ENSDART00000079734
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
chr14_+_740032 1.32 ENSDART00000165014
klotho beta
chr7_+_59649746 1.31 ENSDART00000181067
ribosomal protein L34
chr9_+_33216945 1.31 ENSDART00000134029
si:ch211-125e6.12
chr8_-_979735 1.30 ENSDART00000149612
zinc finger protein 366
chr1_+_58312680 1.29 ENSDART00000138007
si:dkey-222h21.10
chr14_-_48103207 1.28 ENSDART00000056712
electron-transferring-flavoprotein dehydrogenase
chr13_-_39160018 1.28 ENSDART00000168795
collagen, type IX, alpha 1b
chr23_+_44634187 1.28 ENSDART00000143688
si:ch73-265d7.2
chr7_+_59649399 1.27 ENSDART00000123520
ENSDART00000040771
ribosomal protein L34
chr2_+_58377395 1.27 ENSDART00000193511
VAMP (vesicle-associated membrane protein)-associated protein A, like
chr4_+_34119824 1.26 ENSDART00000165637
si:ch211-223g7.6
chr3_-_31618037 1.26 ENSDART00000183547
minamoto
chr7_-_40578733 1.26 ENSDART00000173926
ENSDART00000010035
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr8_-_50132860 1.24 ENSDART00000149964
anthrax toxin receptor 1a
chr1_+_57050899 1.24 ENSDART00000152601
si:ch211-1f22.14
chr18_-_127558 1.24 ENSDART00000149556
transient receptor potential cation channel, subfamily M, member 7
chr14_-_34700633 1.24 ENSDART00000150358
actin binding LIM protein family, member 3
chr13_+_13668991 1.24 ENSDART00000148266
Pim proto-oncogene, serine/threonine kinase, related 48
chr19_+_32158010 1.23 ENSDART00000005255
mitochondrial ribosomal protein L53
chr15_+_19797918 1.21 ENSDART00000113314
si:ch211-229d2.5
chr16_-_29146624 1.21 ENSDART00000159814
ENSDART00000009826
myocyte enhancer factor 2d
chr1_+_24387659 1.21 ENSDART00000130356
quinoid dihydropteridine reductase b2
chr16_-_1503023 1.19 ENSDART00000036348
single-minded family bHLH transcription factor 1a
chr22_-_10774735 1.18 ENSDART00000081156
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr20_+_6535438 1.17 ENSDART00000145763
si:ch211-191a24.4
chr5_+_43870389 1.17 ENSDART00000141002
zgc:112966
chr10_-_29272707 1.16 ENSDART00000022605
ENSDART00000184594
ENSDART00000185371
transmembrane protein 126A
chr2_-_25143373 1.15 ENSDART00000160108
neutral cholesterol ester hydrolase 1a
chr4_+_64921810 1.15 ENSDART00000157654

chr8_+_32742650 1.15 ENSDART00000138117
hemicentin 2
chr12_+_22870372 1.15 ENSDART00000182264
ENSDART00000191789
ENSDART00000130594
ENSDART00000190433
actin filament associated protein 1
chr4_-_56157199 1.14 ENSDART00000169806
si:ch211-207e19.15
chr2_+_35880600 1.12 ENSDART00000004277
laminin, gamma 1
chr5_+_9246018 1.11 ENSDART00000081769
ENSDART00000183189
sushi domain containing 1
chr22_-_38274188 1.11 ENSDART00000139420
ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr13_+_713941 1.10 ENSDART00000109737
cytochrome c oxidase assembly homolog 15 (yeast)
chr13_-_39159810 1.10 ENSDART00000131508
collagen, type IX, alpha 1b
chr20_-_49650293 1.09 ENSDART00000151239
collagen, type XII, alpha 1b
chr1_+_57176256 1.08 ENSDART00000152741
si:dkey-27j5.6
chr22_-_14346575 1.08 ENSDART00000136326
si:dkeyp-122a9.1
chr2_-_7666021 1.07 ENSDART00000180007

chr19_-_27564980 1.06 ENSDART00000171967
si:dkeyp-46h3.8
chr4_+_38981587 1.06 ENSDART00000142713
si:dkey-66k12.3
chr4_-_64605318 1.05 ENSDART00000170391
zinc finger protein 1099
chr9_+_35077546 1.05 ENSDART00000142688
si:dkey-192g7.3
chr21_+_38089036 1.03 ENSDART00000147219
Kruppel-like factor 8
chr8_+_4745340 1.02 ENSDART00000182894
ubiquitin recognition factor in ER associated degradation 1
chr19_-_25005609 1.01 ENSDART00000151129
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 2
chr24_-_21913426 1.00 ENSDART00000081178
C1q and TNF related 9
chr23_+_19790962 1.00 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr7_-_35393900 1.00 ENSDART00000173769
lysophosphatidylcholine acyltransferase 2
chr19_-_3741602 1.00 ENSDART00000170301
bloodthirsty-related gene family, member 22
chr22_+_25184459 0.99 ENSDART00000105308
si:ch211-226h8.4
chr14_-_29859067 0.99 ENSDART00000136380
sorbin and SH3 domain containing 2b
chr19_+_7604527 0.99 ENSDART00000132107
S100 calcium binding protein S
chr1_+_23783349 0.97 ENSDART00000007531
slit homolog 2 (Drosophila)
chr9_-_33121535 0.97 ENSDART00000166371
ENSDART00000138052
zgc:172014
chr23_+_27912079 0.97 ENSDART00000171859

chr12_+_48241841 0.97 ENSDART00000168616
pyrophosphatase (inorganic) 1a
chr1_+_58094551 0.96 ENSDART00000146316
si:ch211-114l13.1
chr3_+_22432069 0.96 ENSDART00000123054
WNK lysine deficient protein kinase 4b
chr6_-_39270851 0.96 ENSDART00000148839
Rho guanine nucleotide exchange factor (GEF) 25b

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 15.2 GO:0003210 cardiac atrium formation(GO:0003210)
1.9 5.7 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
1.6 9.9 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
1.4 10.8 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
1.0 12.9 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.9 2.8 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.7 2.2 GO:1905133 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.6 14.8 GO:0001966 thigmotaxis(GO:0001966)
0.6 5.1 GO:0033292 T-tubule organization(GO:0033292)
0.6 10.0 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.4 1.3 GO:0005991 trehalose metabolic process(GO:0005991)
0.4 2.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.4 3.4 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.4 1.3 GO:0007143 female meiotic division(GO:0007143)
0.4 2.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.4 1.6 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.4 4.0 GO:0007525 somatic muscle development(GO:0007525)
0.4 1.2 GO:0072020 proximal straight tubule development(GO:0072020)
0.4 10.2 GO:0007520 myoblast fusion(GO:0007520)
0.4 2.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 7.9 GO:0006825 copper ion transport(GO:0006825)
0.3 3.1 GO:1901998 toxin transport(GO:1901998)
0.3 1.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.3 1.0 GO:0007414 axonal defasciculation(GO:0007414)
0.3 2.3 GO:1902902 negative regulation of autophagosome maturation(GO:1901097) negative regulation of autophagosome assembly(GO:1902902)
0.3 1.0 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.3 3.4 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.3 3.0 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 2.3 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.3 1.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3 0.8 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.3 2.8 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 1.3 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.3 4.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.2 4.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 2.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 1.5 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 1.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 1.3 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.2 1.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 1.0 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.2 0.7 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 7.9 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 1.2 GO:0043589 skin morphogenesis(GO:0043589) mesenchymal cell migration(GO:0090497)
0.2 0.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 0.6 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 0.6 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 12.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.4 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 4.9 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 3.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 13.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 0.4 GO:0033335 anal fin development(GO:0033335)
0.1 1.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 1.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 0.3 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 4.0 GO:0032543 mitochondrial translation(GO:0032543)
0.1 2.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.8 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 2.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.8 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 2.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.5 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 4.5 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 1.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.0 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 1.0 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.4 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.2 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 1.7 GO:0018149 peptide cross-linking(GO:0018149)
0.1 12.5 GO:0006936 muscle contraction(GO:0006936)
0.1 0.8 GO:0030719 P granule organization(GO:0030719)
0.1 0.4 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 2.1 GO:0019835 cytolysis(GO:0019835)
0.1 1.7 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 1.0 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 2.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.7 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 1.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.2 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.6 GO:0050975 sensory perception of touch(GO:0050975)
0.1 1.7 GO:0051014 actin filament severing(GO:0051014)
0.1 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.8 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 2.4 GO:0019226 transmission of nerve impulse(GO:0019226)
0.1 1.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 1.4 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 1.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0097107 positive regulation of synaptic transmission, glutamatergic(GO:0051968) postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444) mitochondrial calcium ion homeostasis(GO:0051560)
0.0 4.8 GO:0006821 chloride transport(GO:0006821)
0.0 1.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 2.0 GO:0030239 myofibril assembly(GO:0030239)
0.0 1.4 GO:0060840 artery development(GO:0060840)
0.0 0.9 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 7.1 GO:0016197 endosomal transport(GO:0016197)
0.0 1.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.5 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.2 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571) arachidonate transport(GO:1903963)
0.0 1.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 2.3 GO:0042552 myelination(GO:0042552)
0.0 5.8 GO:0007005 mitochondrion organization(GO:0007005)
0.0 0.8 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 1.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.6 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 1.0 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.8 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.6 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 1.8 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.5 GO:0051085 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 3.4 GO:0009617 response to bacterium(GO:0009617)
0.0 0.5 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 0.8 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.5 GO:0042476 odontogenesis(GO:0042476)
0.0 0.5 GO:0048599 oocyte development(GO:0048599)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.4 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 5.4 GO:0006412 translation(GO:0006412)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.7 2.8 GO:1990909 Wnt signalosome(GO:1990909)
0.6 4.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 2.7 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 10.5 GO:0031430 M band(GO:0031430)
0.5 1.5 GO:0005592 collagen type XI trimer(GO:0005592)
0.4 0.9 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.4 1.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 16.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.4 1.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 2.0 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 9.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 1.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 1.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 4.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 0.7 GO:0070545 PeBoW complex(GO:0070545)
0.2 7.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.2 8.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 1.8 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.2 3.0 GO:0042555 MCM complex(GO:0042555)
0.2 0.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 2.1 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.5 GO:0017119 Golgi transport complex(GO:0017119)
0.1 9.9 GO:0030018 Z disc(GO:0030018)
0.1 3.3 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.8 GO:1990246 uniplex complex(GO:1990246)
0.1 1.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 2.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.0 GO:0016605 PML body(GO:0016605)
0.0 3.5 GO:0005581 collagen trimer(GO:0005581)
0.0 4.5 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.7 GO:0005686 U2 snRNP(GO:0005686) U12-type spliceosomal complex(GO:0005689)
0.0 1.9 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 1.0 GO:0043186 P granule(GO:0043186)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 2.6 GO:0005840 ribosome(GO:0005840)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 1.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 1.6 GO:0005884 actin filament(GO:0005884)
0.0 1.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.3 GO:0098798 mitochondrial protein complex(GO:0098798)
0.0 0.9 GO:0042383 sarcolemma(GO:0042383)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 3.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.1 GO:0009986 cell surface(GO:0009986)
0.0 0.3 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.5 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
1.8 14.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.6 7.9 GO:0016531 copper chaperone activity(GO:0016531)
1.4 15.2 GO:0032036 myosin heavy chain binding(GO:0032036)
1.2 3.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.0 14.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.0 12.9 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.8 4.6 GO:0042169 SH2 domain binding(GO:0042169)
0.5 2.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.4 1.3 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.4 1.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.3 2.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 1.4 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.3 9.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 1.7 GO:0051430 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 1.3 GO:0033149 FFAT motif binding(GO:0033149)
0.3 1.2 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.3 1.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.3 2.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.4 GO:0009374 biotin binding(GO:0009374)
0.3 2.8 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 4.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 1.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 2.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 1.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 2.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 1.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 4.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.3 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.5 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.6 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 1.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 1.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.1 1.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 3.5 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.4 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 24.8 GO:0051015 actin filament binding(GO:0051015)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.4 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.6 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 9.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.0 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 5.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.8 GO:0005178 integrin binding(GO:0005178)
0.0 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 1.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.0 1.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 1.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 8.1 GO:0003924 GTPase activity(GO:0003924)
0.0 8.0 GO:0016887 ATPase activity(GO:0016887)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 4.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 1.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 2.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.6 PID ATR PATHWAY ATR signaling pathway
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 9.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 1.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 3.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 5.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 2.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 1.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 3.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 3.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.1 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis