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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for nr2e1

Z-value: 0.52

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Transcription factors associated with nr2e1

Gene Symbol Gene ID Gene Info
ENSDARG00000017107 nuclear receptor subfamily 2, group E, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2e1dr11_v1_chr20_-_32446406_32446406-0.279.0e-03Click!

Activity profile of nr2e1 motif

Sorted Z-values of nr2e1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_7546259 7.16 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr9_-_6380653 3.00 ENSDART00000078523
esophageal cancer related gene 4a
chr24_+_28614576 2.83 ENSDART00000184941
ATP-binding cassette, sub-family A (ABC1), member 4a
chr23_-_19682971 2.34 ENSDART00000048891
zgc:193598
chr1_-_33645967 2.31 ENSDART00000192758
claudin g
chr11_-_29946640 2.28 ENSDART00000079175
zgc:113276
chr19_-_38539670 2.14 ENSDART00000136775
collagen, type XVI, alpha 1
chr4_-_77116266 2.06 ENSDART00000174249

chr16_+_20915319 1.99 ENSDART00000079383
homeobox A9b
chr4_-_77125693 1.92 ENSDART00000174256

chr4_-_77120928 1.88 ENSDART00000174154

chr21_+_5129513 1.78 ENSDART00000102572
thrombospondin 4b
chr7_+_55112922 1.74 ENSDART00000073549
snail family zinc finger 3
chr9_-_23944470 1.70 ENSDART00000138754
collagen, type VI, alpha 3
chr5_+_9246018 1.69 ENSDART00000081769
ENSDART00000183189
sushi domain containing 1
chr4_-_837768 1.58 ENSDART00000185280
ENSDART00000135618
sine oculis binding protein homolog (Drosophila) b
chr25_-_16724913 1.44 ENSDART00000157075
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 2
chr14_-_858985 1.30 ENSDART00000148687
ENSDART00000149375
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr12_-_26423439 1.28 ENSDART00000113978
synaptopodin 2-like b
chr25_-_16742636 1.28 ENSDART00000192486
ENSDART00000192711
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 1
chr17_+_5985933 1.23 ENSDART00000190844
zgc:194275
chr15_-_33834577 1.22 ENSDART00000163354
matrix metallopeptidase 13b
chr22_-_22301672 1.20 ENSDART00000111711
chromatin assembly factor 1, subunit A (p150)
chr10_+_10351685 1.19 ENSDART00000109432
cerebral endothelial cell adhesion molecule
chr5_+_13870340 1.19 ENSDART00000160690
hexokinase 2
chr18_+_3530769 1.18 ENSDART00000163469
si:ch73-338a16.3
chr12_+_22674030 1.17 ENSDART00000153254
ENSDART00000152930
cell division cycle associated 9
chr18_-_5542351 1.15 ENSDART00000129459
spermatogenesis associated 5-like 1
chr7_-_3693303 1.15 ENSDART00000166949
si:ch211-282j17.13
chr6_-_15101477 1.13 ENSDART00000187713
ENSDART00000124132
four and a half LIM domains 2b
chr22_-_22301929 1.13 ENSDART00000142027
chromatin assembly factor 1, subunit A (p150)
chr15_+_34675660 1.08 ENSDART00000009127
lymphotoxin alpha (TNF superfamily, member 1)
chr13_-_35892243 1.06 ENSDART00000002750
ENSDART00000122810
ENSDART00000162399
transforming, acidic coiled-coil containing protein 3
chr9_-_31135901 1.02 ENSDART00000113027
ENSDART00000193210
ENSDART00000128896
si:ch211-184m13.4
chr25_-_16742438 1.00 ENSDART00000156091
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 1
chr21_+_6394929 0.96 ENSDART00000138600
si:ch211-225g23.1
chr7_+_39416336 0.95 ENSDART00000171783

chr2_+_30249977 0.93 ENSDART00000109160
ENSDART00000135171
transmembrane protein 70
chr13_-_25284379 0.84 ENSDART00000124167
vinculin a
chr16_+_38360002 0.81 ENSDART00000087346
ENSDART00000148101
zgc:113232
chr22_+_19407531 0.81 ENSDART00000141060
si:dkey-78l4.2
chr6_-_29007493 0.80 ENSDART00000065139
growth factor independent 1A transcription repressor b
chr22_-_24880824 0.80 ENSDART00000061165
vitellogenin 2
chr10_-_20650302 0.80 ENSDART00000142028
ENSDART00000064662
Ras association (RalGDS/AF-6) domain family member 2b
chr15_-_18213515 0.79 ENSDART00000101635
bloodthirsty-related gene family, member 21
chr7_-_3669868 0.79 ENSDART00000172907
si:ch211-282j17.12
chr13_-_25284716 0.75 ENSDART00000039828
vinculin a
chr8_+_4838114 0.75 ENSDART00000146667
es1 protein
chr1_-_9130136 0.75 ENSDART00000113013
partner and localizer of BRCA2
chr2_-_55861351 0.74 ENSDART00000059003
retinal homeobox gene 2
chr7_-_59047720 0.74 ENSDART00000184831

chr2_+_33926606 0.74 ENSDART00000111430
kinesin family member 2C
chr7_-_66137065 0.74 ENSDART00000145843
parathyroid hormone 1b
chr23_+_37185247 0.73 ENSDART00000146269
von Willebrand factor A domain containing 5B1
chr19_-_46775562 0.73 ENSDART00000187144
actin binding Rho activating protein b
chr15_-_4485828 0.72 ENSDART00000062868
transcription factor Dp-2
chr24_+_23742690 0.69 ENSDART00000130162
transcription factor 24
chr18_-_37407235 0.68 ENSDART00000132315
centrosomal protein 126
chr20_+_47196506 0.67 ENSDART00000153040
zinc finger protein 975
chr2_+_17524278 0.66 ENSDART00000165633
Pim proto-oncogene, serine/threonine kinase, related 196
chr15_-_39948635 0.65 ENSDART00000114836
mutS homolog 5
chr5_+_30680804 0.64 ENSDART00000078049
PDZ domain containing 3b
chr17_-_48743076 0.64 ENSDART00000173117
potassium channel, subfamily K, member 17
chr5_-_38197080 0.62 ENSDART00000140708
si:ch211-284e13.9
chr13_+_24671481 0.61 ENSDART00000001678
ADAM metallopeptidase domain 8a
chr23_+_39970425 0.61 ENSDART00000165376
FYVE and coiled-coil domain containing 1a
chr17_-_49581414 0.60 ENSDART00000106339

chr4_+_59748607 0.60 ENSDART00000108499
zinc finger protein 1068
chr5_-_48285756 0.60 ENSDART00000183495
myocyte enhancer factor 2cb
chr25_-_16160494 0.60 ENSDART00000146880
si:dkey-80c24.4
chr13_-_35892051 0.57 ENSDART00000145884
transforming, acidic coiled-coil containing protein 3
chr7_-_26571994 0.56 ENSDART00000128801
si:dkey-62k3.6
chr14_+_2487672 0.56 ENSDART00000170629
ENSDART00000123063
fibroblast growth factor 18a
chr6_+_58622831 0.56 ENSDART00000128793
Sp7 transcription factor
chr25_-_15507523 0.55 ENSDART00000134166
si:dkeyp-67e1.3
chr20_+_38257766 0.55 ENSDART00000147485
ENSDART00000149160
chemokine (C-C motif) ligand 38, duplicate 6
chr12_-_34295298 0.55 ENSDART00000182789

chr1_+_44003654 0.55 ENSDART00000131337
si:dkey-22i16.10
chr7_+_4648398 0.55 ENSDART00000148099
si:dkey-83f18.3
chr12_+_15078124 0.54 ENSDART00000187571

chr24_+_35827766 0.53 ENSDART00000144700
si:dkeyp-7a3.1
chr25_-_12515741 0.52 ENSDART00000159487
si:ch211-280a23.2
chr21_+_19834072 0.52 ENSDART00000147555
coiled-coil domain containing 80 like 2
chr23_+_2669 0.51 ENSDART00000011146
twist3
chr9_+_27876146 0.51 ENSDART00000133997
armadillo repeat containing 8
chr21_+_28535203 0.51 ENSDART00000184950

chr19_+_48176745 0.50 ENSDART00000164963
PR domain containing 1b, with ZNF domain
chr5_+_60934534 0.50 ENSDART00000065025
rabphilin 3A-like (without C2 domains)
chr22_+_28969071 0.50 ENSDART00000163427
Pim proto-oncogene, serine/threonine kinase, related 95
chr6_-_49655879 0.47 ENSDART00000191594
adenomatosis polyposis coli down-regulated 1-like
chr9_+_7068832 0.47 ENSDART00000186685

chr4_+_76619791 0.46 ENSDART00000184042
membrane-spanning 4-domains, subfamily A, member 17A.8
chr4_-_59159690 0.44 ENSDART00000164706
zinc finger protein 1149
chr21_-_28901095 0.44 ENSDART00000180820
CXXC finger protein 5a
chr10_-_35177257 0.44 ENSDART00000077426
POM121 transmembrane nucleoporin
chr5_+_38886499 0.43 ENSDART00000076845
Fraser extracellular matrix complex subunit 1
chr20_-_1176631 0.43 ENSDART00000152255
gamma-aminobutyric acid (GABA) A receptor, rho 2b
chr4_-_37708661 0.43 ENSDART00000168788
zinc finger protein 1139
chr5_-_15321451 0.42 ENSDART00000139203
thioredoxin reductase 2, tandem duplicate 1
chr25_-_13202208 0.42 ENSDART00000168155
si:ch211-194m7.4
chr1_-_52292235 0.42 ENSDART00000132638
si:dkey-121b10.7
chr25_-_31433512 0.42 ENSDART00000067028
zgc:172145
chr20_+_51006362 0.42 ENSDART00000028084
membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5)
chr23_-_16484383 0.41 ENSDART00000187839
si:dkeyp-100a5.4
chr12_-_43982343 0.41 ENSDART00000161539

chr19_+_1606185 0.41 ENSDART00000092183
leucine rich repeat containing 3B
chr19_+_28284120 0.41 ENSDART00000103862
mitochondrial ribosomal protein L36
chr4_-_39942347 0.41 ENSDART00000124410
zinc finger protein 979
chr13_-_12660318 0.40 ENSDART00000008498
alcohol dehydrogenase 8a
chr18_-_41232297 0.40 ENSDART00000036928
F-box protein 36a
chr11_+_24314148 0.40 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr15_+_15314189 0.40 ENSDART00000156830
calcium/calmodulin-dependent protein kinase kinase 1, alpha b
chr4_+_39055027 0.39 ENSDART00000150397
zinc finger protein 977
chr21_+_5508167 0.39 ENSDART00000157702
lymphocyte antigen 6 family member M4
chr2_-_14272083 0.39 ENSDART00000169986
Tctex1 domain containing 1
chr15_-_1822548 0.38 ENSDART00000082026
ENSDART00000180230
matrix metallopeptidase 28
chr15_-_1822166 0.37 ENSDART00000156883
matrix metallopeptidase 28
chr15_+_46108548 0.37 ENSDART00000099023
leucine rich repeat and fibronectin type III domain containing 1
chr4_+_54618332 0.36 ENSDART00000171824
si:ch211-227e10.2
chr5_+_43782267 0.35 ENSDART00000130355
nitric oxide synthase 2a, inducible
chr5_+_61508418 0.34 ENSDART00000023676
branched chain ketoacid dehydrogenase kinase
chr5_-_68927728 0.34 ENSDART00000132838
ankyrin 1, erythrocytic a
chr4_+_50572302 0.33 ENSDART00000150766
ENSDART00000150682
zinc finger protein 977
chr15_-_38186537 0.33 ENSDART00000012872
cholinergic receptor, nicotinic, alpha 10a
chr13_-_15986871 0.33 ENSDART00000189394
IKAROS family zinc finger 1 (Ikaros)
chr7_-_41693004 0.32 ENSDART00000121509
MAM and LDL receptor class A domain containing 1
chr21_+_25375172 0.32 ENSDART00000078748
odorant receptor, family H, subfamily 132, member 5
chr17_+_28073062 0.32 ENSDART00000182021

chr16_-_39178979 0.31 ENSDART00000158894
si:dkey-99n20.6
chr22_-_17652112 0.31 ENSDART00000189205
histocompatibility (minor) HA-1 b
chr5_+_60934345 0.31 ENSDART00000179772
rabphilin 3A-like (without C2 domains)
chr1_-_46244523 0.30 ENSDART00000143908
si:ch211-138g9.3
chr4_+_35227135 0.30 ENSDART00000161023
ENSDART00000182403
si:ch211-276i6.1
chr8_-_50287949 0.30 ENSDART00000023639
NK2 transcription factor related 7
chr22_+_24646339 0.30 ENSDART00000183865
lysophosphatidic acid receptor 3
chr4_+_29703166 0.29 ENSDART00000132876
si:ch211-214c20.1
chr4_-_43071336 0.29 ENSDART00000150773
zinc finger protein 1072
chr14_-_26377044 0.28 ENSDART00000022236
empty spiracles homeobox 3
chr4_+_60381608 0.27 ENSDART00000167351
zinc finger protein 1130
chr13_-_24396199 0.27 ENSDART00000181093
TATA box binding protein
chr7_+_52753067 0.25 ENSDART00000053814
mitochondrial methionyl-tRNA formyltransferase
chr16_+_10429770 0.25 ENSDART00000173132
valyl-tRNA synthetase
chr16_+_28932038 0.24 ENSDART00000149480
natriuretic peptide receptor 1b
chr24_-_21587335 0.24 ENSDART00000091528
G protein-coupled receptor 12
chr2_-_20890429 0.24 ENSDART00000149989
phosducin a
chr10_+_8554929 0.22 ENSDART00000190849
TBC1 domain family, member 10Ab
chr13_-_37465524 0.22 ENSDART00000100324
ENSDART00000147336
protein phosphatase 2, regulatory subunit B', epsilon isoform b
chr21_+_37411547 0.22 ENSDART00000076320
mitochondrial ribosomal protein S17
chr17_+_12408188 0.21 ENSDART00000105218
ketohexokinase
chr9_+_51147380 0.20 ENSDART00000003913
interferon induced with helicase C domain 1
chr21_+_20356458 0.19 ENSDART00000135816
phosphodiesterase 6B, cGMP-specific, rod, beta
chr16_+_20947439 0.19 ENSDART00000137344
src kinase associated phosphoprotein 2
chr10_-_1625080 0.19 ENSDART00000137285
nucleoporin 155
chr5_-_63663811 0.17 ENSDART00000111403
cdkn1a interacting zinc finger protein 1b
chr12_+_25945560 0.17 ENSDART00000109799
multimerin 2b
chr16_-_26855936 0.17 ENSDART00000167320
ENSDART00000078119
INO80 complex subunit C
chr17_-_12408109 0.16 ENSDART00000155509
ankyrin repeat and EF-hand domain containing 1b
chr4_-_2868112 0.16 ENSDART00000133843
phosphodiesterase 3A, cGMP-inhibited
chr4_+_37239091 0.15 ENSDART00000172013
zinc finger protein 973
chr7_+_73332486 0.15 ENSDART00000174119
ENSDART00000092051
ENSDART00000192388

chr12_-_23128746 0.14 ENSDART00000170018
armadillo repeat containing 4
chr12_+_9551667 0.14 ENSDART00000048493
ENSDART00000166178
prolyl 4-hydroxylase, alpha polypeptide I a
chr2_+_10771787 0.13 ENSDART00000187782
growth factor independent 1A transcription repressor a
chr7_+_25135739 0.13 ENSDART00000167326
exocyst complex component 6B
chr4_-_59057046 0.13 ENSDART00000150249
zinc finger protein 1132
chr4_+_5196469 0.13 ENSDART00000067386
RAD51 associated protein 1
chr2_-_30249746 0.12 ENSDART00000124153
ENSDART00000142575
elongin C paralog b
chr11_+_25508129 0.12 ENSDART00000011250
transcription factor binding to IGHM enhancer 3b
chr6_+_46668717 0.12 ENSDART00000064853
oxytocin receptor like
chr2_+_21486529 0.12 ENSDART00000047468
inhibin, beta Ab
chr2_-_48255843 0.12 ENSDART00000056277
GRB10 interacting GYF protein 2
chr1_+_8304904 0.11 ENSDART00000168631
calcium channel, voltage-dependent, T type, alpha 1H subunit b
chr4_-_72287764 0.11 ENSDART00000125452
ENSDART00000189437
si:cabz01071911.3
chr15_+_42599501 0.10 ENSDART00000177646
glutamate receptor, ionotropic, kainate 1b
chr10_-_36240806 0.10 ENSDART00000171468
odorant receptor, family D, subfamily 109, member 2
chr4_+_52959625 0.09 ENSDART00000158240
si:dkey-201g16.1
chr1_+_57311901 0.09 ENSDART00000149397
mycbp associated protein
chr7_-_38689562 0.08 ENSDART00000167209
apelin receptor 2
chr24_+_27511734 0.06 ENSDART00000105771
chemokine (C-X-C motif) ligand 32b, duplicate 1
chr8_+_23034718 0.05 ENSDART00000184512
YTH N(6)-methyladenosine RNA binding protein 1
chr14_+_44774089 0.05 ENSDART00000098643
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr23_-_16485190 0.05 ENSDART00000155038
si:dkeyp-100a5.4
chr16_+_33111947 0.05 ENSDART00000058473
cannabinoid receptor 2
chr2_-_14271874 0.04 ENSDART00000189390
Tctex1 domain containing 1
chr4_-_8060962 0.03 ENSDART00000146622
WNK lysine deficient protein kinase 1b
chr17_+_43843536 0.02 ENSDART00000164097

chr13_+_23093743 0.01 ENSDART00000148034
phosphoinositide-3-kinase adaptor protein 1
chr6_-_21534301 0.01 ENSDART00000126186
proteasome 26S subunit, non-ATPase 12

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2e1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.5 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.9 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 1.8 GO:0035989 tendon development(GO:0035989)
0.3 1.6 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.2 1.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.2 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 2.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.8 GO:0050764 regulation of phagocytosis(GO:0050764)
0.1 0.6 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 1.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 0.4 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.2 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 0.6 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 2.0 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.7 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.4 GO:0030826 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.4 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.1 0.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 0.2 GO:0032648 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.0 1.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0009750 response to fructose(GO:0009750)
0.0 0.1 GO:0007567 parturition(GO:0007567) maternal process involved in parturition(GO:0060137)
0.0 0.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 2.3 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.3 GO:0003207 cardiac chamber formation(GO:0003207)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 2.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.7 GO:0035775 pronephric glomerulus morphogenesis(GO:0035775)
0.0 1.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.6 GO:0060914 heart formation(GO:0060914)
0.0 4.0 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 1.2 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 3.2 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0033186 CAF-1 complex(GO:0033186)
0.2 0.6 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2 1.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.5 GO:0034657 GID complex(GO:0034657)
0.1 1.3 GO:0005903 brush border(GO:0005903)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 1.8 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 3.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 2.4 GO:0030018 Z disc(GO:0030018)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.6 GO:0042383 sarcolemma(GO:0042383)
0.0 1.7 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 4.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0070449 elongin complex(GO:0070449)
0.0 0.2 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 1.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 1.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 0.6 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.2 0.6 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.2 0.8 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 1.2 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.1 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 3.4 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0002020 protease binding(GO:0002020)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004990 oxytocin receptor activity(GO:0004990)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 3.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 1.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.6 PID AURORA A PATHWAY Aurora A signaling
0.0 1.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 3.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter