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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish
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Results for pax1a+pax1b_pax9
Z-value: 0.66
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Transcription factors associated with pax1a+pax1b_pax9
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
pax1a
|
ENSDARG00000008203 | paired box 1a |
|
pax1b
|
ENSDARG00000073814 | paired box 1b |
|
pax9
|
ENSDARG00000053829 | paired box 9 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pax9 | dr11_v1_chr17_-_38244117_38244117 | 0.14 | 1.7e-01 | Click! |
| pax1b | dr11_v1_chr20_-_48700370_48700370 | 0.14 | 1.7e-01 | Click! |
| pax1a | dr11_v1_chr17_+_42274240_42274240 | 0.04 | 7.3e-01 | Click! |
Activity profile of pax1a+pax1b_pax9 motif
Sorted Z-values of pax1a+pax1b_pax9 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_44282796 | 27.39 |
ENSDART00000163040
ENSDART00000166923 ENSDART00000056372 ENSDART00000109251 ENSDART00000132682 |
mpz
|
myelin protein zero |
| chr2_-_44283554 | 23.27 |
ENSDART00000184684
|
mpz
|
myelin protein zero |
| chr21_+_13861589 | 19.04 |
ENSDART00000015629
ENSDART00000171306 |
stxbp1a
|
syntaxin binding protein 1a |
| chr25_+_6306885 | 7.07 |
ENSDART00000142705
ENSDART00000067510 |
crabp1a
|
cellular retinoic acid binding protein 1a |
| chr12_-_18483348 | 4.99 |
ENSDART00000152757
|
tex2l
|
testis expressed 2, like |
| chr12_-_7854216 | 3.89 |
ENSDART00000149594
|
ank3b
|
ankyrin 3b |
| chr10_-_39154594 | 2.95 |
ENSDART00000148825
|
slc37a4b
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4b |
| chr5_-_29643381 | 2.87 |
ENSDART00000034849
|
grin1b
|
glutamate receptor, ionotropic, N-methyl D-aspartate 1b |
| chr1_+_39553040 | 2.83 |
ENSDART00000137676
|
tenm3
|
teneurin transmembrane protein 3 |
| chr20_+_12702923 | 2.75 |
ENSDART00000163499
|
zgc:153383
|
zgc:153383 |
| chr25_-_29087925 | 2.17 |
ENSDART00000171758
|
rpp25a
|
ribonuclease P and MRP subunit p25, a |
| chr10_-_39154778 | 2.10 |
ENSDART00000186811
|
slc37a4b
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4b |
| chr3_-_50277959 | 2.03 |
ENSDART00000082773
ENSDART00000139524 |
arl16
|
ADP-ribosylation factor-like 16 |
| chr2_+_394166 | 1.90 |
ENSDART00000155733
|
mylk4a
|
myosin light chain kinase family, member 4a |
| chr9_-_13871935 | 1.70 |
ENSDART00000146597
|
raph1a
|
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a |
| chr16_+_20738740 | 1.44 |
ENSDART00000079343
|
jazf1b
|
JAZF zinc finger 1b |
| chr1_-_46343999 | 1.41 |
ENSDART00000145117
ENSDART00000193233 |
atp11a
|
ATPase phospholipid transporting 11A |
| chr11_+_24804556 | 1.30 |
ENSDART00000082761
ENSDART00000186283 |
adipor1a
|
adiponectin receptor 1a |
| chr8_+_48966165 | 1.23 |
ENSDART00000165425
|
aak1a
|
AP2 associated kinase 1a |
| chr4_-_8902406 | 1.21 |
ENSDART00000192962
|
mpped1
|
metallophosphoesterase domain containing 1 |
| chr1_-_51261420 | 1.17 |
ENSDART00000168685
|
kif16ba
|
kinesin family member 16Ba |
| chr11_-_4023940 | 1.03 |
ENSDART00000058728
ENSDART00000171245 |
nek4
|
NIMA-related kinase 4 |
| chr9_+_38074082 | 1.01 |
ENSDART00000017833
|
cacnb4a
|
calcium channel, voltage-dependent, beta 4a subunit |
| chr9_+_34334156 | 0.99 |
ENSDART00000144272
|
pou2f1b
|
POU class 2 homeobox 1b |
| chr2_+_49864219 | 0.85 |
ENSDART00000187744
|
rpl37
|
ribosomal protein L37 |
| chr24_+_3478871 | 0.79 |
ENSDART00000111491
ENSDART00000134598 ENSDART00000142407 |
wdr37
|
WD repeat domain 37 |
| chr17_+_956821 | 0.76 |
ENSDART00000082101
|
ppp2r5ca
|
protein phosphatase 2, regulatory subunit B', gamma a |
| chr3_+_47322494 | 0.69 |
ENSDART00000102202
|
ppap2d
|
phosphatidic acid phosphatase type 2D |
| chr20_-_31075972 | 0.58 |
ENSDART00000122927
|
si:ch211-198b3.4
|
si:ch211-198b3.4 |
| chr6_-_41079209 | 0.41 |
ENSDART00000151592
|
rab44
|
RAB44, member RAS oncogene family |
| chr18_-_48550426 | 0.25 |
ENSDART00000145189
|
kcnj1a.1
|
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 |
| chr23_+_43255328 | 0.23 |
ENSDART00000102712
|
tgm2a
|
transglutaminase 2, C polypeptide A |
| chr15_+_41836104 | 0.20 |
ENSDART00000137434
|
pxylp1
|
2-phosphoxylose phosphatase 1 |
| chr17_-_23674065 | 0.14 |
ENSDART00000104735
ENSDART00000182952 |
ptena
|
phosphatase and tensin homolog A |
| chr23_+_9522781 | 0.03 |
ENSDART00000136486
|
osbpl2b
|
oxysterol binding protein-like 2b |
Network of associatons between targets according to the STRING database.
First level regulatory network of pax1a+pax1b_pax9
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 7.1 | GO:0016103 | diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653) |
| 0.7 | 2.8 | GO:0070983 | dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385) |
| 0.4 | 19.4 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.2 | 2.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.2 | 2.9 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.1 | 1.3 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.0 | 0.8 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 1.4 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.2 | GO:0042762 | regulation of sulfur metabolic process(GO:0042762) |
| 0.0 | 0.8 | GO:0031952 | regulation of protein autophosphorylation(GO:0031952) |
| 0.0 | 1.0 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.2 | GO:0018149 | peptide cross-linking(GO:0018149) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.8 | 50.7 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.3 | 2.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.2 | 19.4 | GO:0030141 | secretory granule(GO:0030141) |
| 0.2 | 2.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 0.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.8 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 1.4 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 1.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 1.2 | GO:0005871 | kinesin complex(GO:0005871) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 7.1 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.5 | 19.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.9 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 2.9 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.8 | GO:0072542 | phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542) |
| 0.0 | 1.2 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 1.0 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.7 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.0 | 5.1 | GO:0015293 | symporter activity(GO:0015293) |
| 0.0 | 2.8 | GO:0042803 | protein homodimerization activity(GO:0042803) |
| 0.0 | 0.2 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.0 | 0.8 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 0.1 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |