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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pax7a+pax7b+prop1

Z-value: 0.59

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Transcription factors associated with pax7a+pax7b+prop1

Gene Symbol Gene ID Gene Info
ENSDARG00000039756 PROP paired-like homeobox 1
ENSDARG00000070818 paired box 7b
ENSDARG00000100398 paired box 7a
ENSDARG00000109950 PROP paired-like homeobox 1
ENSDARG00000111233 paired box 7a
ENSDARG00000114449 PROP paired-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax7bdr11_v1_chr23_+_20863145_208631450.213.8e-02Click!
pax7adr11_v1_chr11_+_41242644_412426440.213.8e-02Click!
prop1dr11_v1_chr13_+_8677166_8677304-0.019.5e-01Click!

Activity profile of pax7a+pax7b+prop1 motif

Sorted Z-values of pax7a+pax7b+prop1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_1012269 4.36 ENSDART00000159835

chr6_-_58764672 4.32 ENSDART00000154322
sterol O-acyltransferase 2
chr5_+_2815021 3.99 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr2_+_6253246 3.32 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr20_-_40755614 3.31 ENSDART00000061247
connexin 32.3
chr10_-_34002185 3.14 ENSDART00000046599
zygote arrest 1-like
chr9_+_8396755 3.08 ENSDART00000043067
zgc:171776
chr20_+_54304800 2.98 ENSDART00000121661
zona pellucida glycoprotein 2, tandem duplicate 6
chr5_+_37903790 2.93 ENSDART00000162470
transmembrane protease, serine 4b
chr24_-_38110779 2.78 ENSDART00000147783
c-reactive protein, pentraxin-related
chr10_+_15255198 2.68 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr25_+_31267268 2.60 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr5_+_32206378 2.55 ENSDART00000126873
ENSDART00000051361
myosin, heavy polypeptide 2, fast muscle specific
chr25_+_3327071 2.50 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr16_-_28658341 2.49 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr21_+_45841731 2.45 ENSDART00000038657
fatty acid hydroxylase domain containing 2
chr10_-_34916208 2.43 ENSDART00000187371
cyclin A1
chr21_+_6751405 2.31 ENSDART00000037265
ENSDART00000146371
olfactomedin 1b
chr11_+_13224281 2.29 ENSDART00000102557
ENSDART00000178706
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr22_-_20695237 2.23 ENSDART00000112722
oogenesis-related gene
chr5_+_28497956 2.21 ENSDART00000191935
notochord formation related
chr21_+_6751760 2.18 ENSDART00000135914
olfactomedin 1b
chr9_+_8390737 2.15 ENSDART00000190891
ENSDART00000176877
ENSDART00000144851
ENSDART00000133880
ENSDART00000142233
zgc:113984
chr21_+_31150438 2.09 ENSDART00000065366
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr17_+_51627209 2.06 ENSDART00000056886
zgc:113142
chr13_-_52089003 2.05 ENSDART00000187600
transmembrane protein 254
chr8_+_24745041 2.01 ENSDART00000148872
solute carrier family 16, member 4
chr25_+_31276842 1.98 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr13_-_9886579 1.84 ENSDART00000101926
si:ch211-117n7.7
chr22_+_7738966 1.82 ENSDART00000147073
si:ch73-44m9.5
chr5_-_68333081 1.81 ENSDART00000168786
linker histone H1M
chr16_+_47207691 1.78 ENSDART00000062507
islet cell autoantigen 1
chr23_+_32101202 1.74 ENSDART00000000992
zgc:56699
chr23_+_26026383 1.71 ENSDART00000141553
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr10_+_33393829 1.70 ENSDART00000163458
ENSDART00000115379
zgc:153345
chr24_-_27400017 1.69 ENSDART00000145829
chemokine (C-C motif) ligand 34b, duplicate 1
chr15_+_34934568 1.66 ENSDART00000165210
zgc:66024
chr17_-_4245902 1.65 ENSDART00000151851
growth differentiation factor 3
chr20_-_33566640 1.62 ENSDART00000159729
si:dkey-65b13.9
chr13_-_29420885 1.61 ENSDART00000024225
choline O-acetyltransferase a
chr25_+_22320738 1.57 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr8_+_45334255 1.56 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr21_+_31150773 1.55 ENSDART00000126205
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr4_-_8043839 1.54 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
chr7_+_56577522 1.53 ENSDART00000149130
ENSDART00000149624
haptoglobin
chr3_+_3681116 1.51 ENSDART00000109618
ADP-ribosyltransferase 4 (Dombrock blood group)
chr9_-_12443726 1.49 ENSDART00000102434
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr4_+_5249494 1.48 ENSDART00000150391
si:ch211-214j24.14
chr17_-_12336987 1.45 ENSDART00000172001
synaptosomal-associated protein, 25b
chr5_+_32260502 1.44 ENSDART00000149020
si:ch211-158m24.12
chr4_-_5019113 1.42 ENSDART00000189321
ENSDART00000081990
striatin interacting protein 2
chr16_-_12173554 1.42 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr22_+_7439186 1.42 ENSDART00000190667
zgc:92041
chr21_+_28478663 1.41 ENSDART00000077887
ENSDART00000134150
solute carrier family 22 (organic anion transporter), member 6, like
chr17_+_23298928 1.41 ENSDART00000153652
zgc:165461
chr4_-_815871 1.38 ENSDART00000067455
dihydropyrimidinase-like 5b
chr6_+_21001264 1.38 ENSDART00000044519
ENSDART00000151278
connexin 44.2
chr25_+_36292057 1.37 ENSDART00000152329
brambleberry
chr6_+_32882821 1.37 ENSDART00000075780
growth hormone releasing hormone receptor b
chr15_+_44366556 1.36 ENSDART00000133449
guanylate cyclase 1 soluble subunit alpha 2
chr10_+_6884627 1.32 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr8_-_50888806 1.30 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr9_+_34127005 1.28 ENSDART00000167384
ENSDART00000078065
coagulation factor V
chr7_+_59020972 1.27 ENSDART00000157873
3-hydroxyacyl-CoA dehydratase 1
chr2_-_21082695 1.24 ENSDART00000032502
nebulette
chr10_+_21867307 1.24 ENSDART00000126629
cerebellin 17
chr5_-_1203455 1.23 ENSDART00000172177
surfeit gene 4
chr12_+_18578597 1.19 ENSDART00000134944
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr4_+_18804317 1.16 ENSDART00000101043
solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2
chr13_-_8692860 1.16 ENSDART00000058107
multiple coagulation factor deficiency 2
chr18_+_7073130 1.14 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
chr7_+_23515966 1.12 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr9_+_54039006 1.12 ENSDART00000112441
toll-like receptor 7
chr16_-_12173399 1.12 ENSDART00000142574
calsyntenin 3
chr15_+_29727799 1.10 ENSDART00000182006
zgc:153372
chr12_+_47081783 1.09 ENSDART00000158568
5-methyltetrahydrofolate-homocysteine methyltransferase
chr17_-_2834764 1.09 ENSDART00000024027
bradykinin receptor B1
chr10_+_21722892 1.08 ENSDART00000162855
protocadherin 1 gamma 13
chr19_-_9867001 1.07 ENSDART00000091695
calcium channel, voltage-dependent, gamma subunit 7a
chr9_+_48761455 1.07 ENSDART00000139631
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr23_-_41965557 1.06 ENSDART00000144183
solute carrier family 1 (glutamate transporter), member 7b
chr1_+_35985813 1.05 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
chr10_-_26738209 1.05 ENSDART00000188590
fibroblast growth factor 13b
chr15_-_33925851 1.04 ENSDART00000187807
ENSDART00000187780
myelin associated glycoprotein
chr12_+_16168342 1.04 ENSDART00000079326
ENSDART00000170024
low density lipoprotein receptor-related protein 2b
chr3_-_13461056 1.03 ENSDART00000137678
F-box and WD repeat domain containing 9
chr21_+_45502621 1.03 ENSDART00000166719
si:dkey-223p19.2
chr13_-_31452516 1.01 ENSDART00000193268
reticulon 1a
chr19_-_5103141 1.00 ENSDART00000150952
triosephosphate isomerase 1a
chr8_+_25767610 0.99 ENSDART00000062406
calcium channel, voltage-dependent, L type, alpha 1S subunit, b
chr2_-_55797318 0.99 ENSDART00000158147
calreticulin 3b
chr7_+_20471315 0.99 ENSDART00000173714
si:dkey-19b23.13
chr4_+_4849789 0.96 ENSDART00000130818
ENSDART00000127751
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr3_+_16722014 0.96 ENSDART00000008711
glycogen synthase 1 (muscle)
chr13_-_39736938 0.95 ENSDART00000141645
zgc:171482
chr2_+_42871831 0.93 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr13_+_35474235 0.92 ENSDART00000181927
McKusick-Kaufman syndrome
chr15_+_34592215 0.92 ENSDART00000099776
tetraspanin 13a
chr19_+_5480327 0.92 ENSDART00000148794
junction plakoglobin b
chr8_-_30979494 0.91 ENSDART00000138959
si:ch211-251j10.3
chr23_-_14766902 0.91 ENSDART00000168113
glutathione synthetase
chr4_-_2219705 0.90 ENSDART00000131046
si:ch73-278m9.1
chr12_-_41684729 0.89 ENSDART00000184461
Janus kinase and microtubule interacting protein 3
chr1_+_12295142 0.88 ENSDART00000158595
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr13_+_8693410 0.88 ENSDART00000138448
tetratricopeptide repeat domain 7A
chr9_+_18829360 0.87 ENSDART00000006514
general transcription factor IIF, polypeptide 2b
chr17_-_40956035 0.86 ENSDART00000124715
si:dkey-16j16.4
chr14_-_49063157 0.86 ENSDART00000021260
septin 8b
chr2_-_42871286 0.85 ENSDART00000087823
adenylate cyclase 8 (brain)
chr23_+_18527028 0.85 ENSDART00000190263
ENSDART00000104545
arginine vasopressin receptor 2a, duplicate b
chr20_-_7583486 0.83 ENSDART00000144729
ubiquitin specific peptidase 24
chr9_-_3866707 0.82 ENSDART00000010378
myosin IIIB
chr9_-_35334642 0.82 ENSDART00000157195
neural cell adhesion molecule 2
chr1_+_17676745 0.81 ENSDART00000030665
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr11_+_41540862 0.81 ENSDART00000173210
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr6_+_7421898 0.81 ENSDART00000043946
coiled-coil domain containing 65
chr23_-_24825863 0.80 ENSDART00000112493
synaptotagmin VIa
chr17_-_6613458 0.80 ENSDART00000175024
si:ch211-189e2.3
chr10_-_20706109 0.79 ENSDART00000124751
Kv channel interacting protein 3b, calsenilin
chr8_-_53044300 0.78 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr3_+_62000822 0.78 ENSDART00000106680
retinoic acid induced 1
chr24_+_40860320 0.78 ENSDART00000161351
golgi reassembly stacking protein 1b
chr1_-_50859053 0.77 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr18_+_45958375 0.77 ENSDART00000108636
adaptor-related protein complex 2, mu 1 subunit, b
chr4_-_948776 0.76 ENSDART00000023483
single-minded family bHLH transcription factor 1b
chr25_-_19420949 0.76 ENSDART00000181338
microtubule-associated protein 1Ab
chr23_+_8989168 0.76 ENSDART00000034380
XK, Kell blood group complex subunit-related family, member 7
chr19_-_5103313 0.75 ENSDART00000037007
triosephosphate isomerase 1a
chr20_-_52902693 0.75 ENSDART00000166115
ENSDART00000161050
cathepsin Bb
chr2_+_50608099 0.75 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr3_+_46459540 0.74 ENSDART00000188150
si:ch211-66e2.5
chr5_+_42097608 0.74 ENSDART00000014404
purinergic receptor P2X, ligand-gated ion channel, 5
chr3_+_21225750 0.74 ENSDART00000139213
zgc:153968
chr7_+_27898091 0.74 ENSDART00000186451
ENSDART00000173510
tubby bipartite transcription factor
chr3_-_6519691 0.73 ENSDART00000165273
ENSDART00000179882
ENSDART00000172292
si:ch73-157i16.3
chr15_+_45544589 0.73 ENSDART00000055978

chr3_+_40164129 0.72 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr20_+_715739 0.72 ENSDART00000136768
myosin VIa
chr16_+_32029090 0.71 ENSDART00000041054
transmembrane channel-like 4
chr2_+_47708853 0.71 ENSDART00000124307
muscleblind-like splicing regulator 1
chr1_+_49668423 0.71 ENSDART00000150880
testis specific, 10
chr6_+_39905021 0.70 ENSDART00000064904
endonuclease, polyU-specific
chr11_-_29737088 0.70 ENSDART00000159828
si:ch211-218g23.6
chr16_-_41646164 0.70 ENSDART00000184257
ATPase secretory pathway Ca2+ transporting 1
chr14_-_858985 0.70 ENSDART00000148687
ENSDART00000149375
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr17_-_22573311 0.70 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exonuclease 1
chr16_+_11660839 0.69 ENSDART00000193911
ENSDART00000143683
si:dkey-250k15.10
chr24_-_7697274 0.69 ENSDART00000186077
synaptotagmin Vb
chr7_-_7692723 0.69 ENSDART00000183352
aminoadipate aminotransferase
chr23_+_28809002 0.68 ENSDART00000134121
ENSDART00000183661
peroxisomal biogenesis factor 14
chr11_+_30057762 0.68 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr13_-_11644806 0.68 ENSDART00000169953
dynactin 1b
chr5_-_20491198 0.68 ENSDART00000183051
ENSDART00000144232
FIC domain containing
chr13_+_6342410 0.68 ENSDART00000065228
CUB and Sushi multiple domains 1a
chr7_-_8712148 0.67 ENSDART00000065488
testis expressed 261
chr8_+_7097929 0.67 ENSDART00000188955
ENSDART00000184772
ENSDART00000109581
ankyrin repeat and BTB (POZ) domain containing 1
chr23_-_37113215 0.67 ENSDART00000146835
zgc:193690
chr17_+_16564921 0.66 ENSDART00000151904
forkhead box N3
chr13_+_35528607 0.65 ENSDART00000075414
ENSDART00000112947
WD repeat domain 27
chr16_-_13281380 0.65 ENSDART00000103882
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr17_-_36896560 0.65 ENSDART00000045287
microtubule-associated protein, RP/EB family, member 3a
chr15_-_2519640 0.64 ENSDART00000047013
signal recognition particle receptor, B subunit
chr9_-_50000144 0.64 ENSDART00000123416
sodium channel, voltage-gated, type I, alpha
chr5_+_12888260 0.64 ENSDART00000175916
galactose-3-O-sulfotransferase 1a
chr24_+_5912635 0.64 ENSDART00000153736
Pim proto-oncogene, serine/threonine kinase, related 63
chr16_+_2820340 0.63 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
chr21_-_2814709 0.63 ENSDART00000097664
semaphorin 4D
chr5_-_12219572 0.63 ENSDART00000167834
nitric oxide synthase 1 (neuronal)
chr14_-_25309058 0.62 ENSDART00000159569
5-hydroxytryptamine receptor 4
chr4_+_9669717 0.62 ENSDART00000004604
si:dkey-153k10.9
chr25_+_34938317 0.62 ENSDART00000042678
vacuolar protein sorting 4a homolog A (S. cerevisiae)
chr12_-_47648538 0.61 ENSDART00000108477
fumarate hydratase
chr15_-_18162647 0.61 ENSDART00000012064
PIH1 domain containing 2
chr14_+_36521005 0.61 ENSDART00000192286
si:dkey-237h12.3
chr18_+_26337869 0.60 ENSDART00000109257
si:ch211-234p18.3
chr22_+_35275468 0.60 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr18_+_38908903 0.60 ENSDART00000159834
myosin VAa
chr20_+_23173710 0.59 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr17_+_5793248 0.58 ENSDART00000153743
retinitis pigmentosa 1-like 1a
chr12_+_16087077 0.58 ENSDART00000141898
zinc finger protein 281b
chr11_-_27867024 0.58 ENSDART00000182136
ENSDART00000187587
eukaryotic translation initiation factor 4 gamma, 3a
chr1_-_29139141 0.58 ENSDART00000075546
ENSDART00000133246
heat shock transcription factor 2 binding protein
chr10_-_14556978 0.58 ENSDART00000126643
zgc:153395
chr12_+_31735159 0.57 ENSDART00000185442
si:dkey-49c17.3
chr7_+_20629411 0.57 ENSDART00000173710
si:dkey-19b23.15
chr10_+_45071603 0.57 ENSDART00000186505
ENSDART00000157573
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr17_-_200316 0.56 ENSDART00000190561

chr17_+_28533102 0.56 ENSDART00000156218
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr19_+_46158078 0.56 ENSDART00000183933
ENSDART00000164055
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr3_-_23407720 0.56 ENSDART00000155658
Rap guanine nucleotide exchange factor (GEF)-like 1
chr24_-_31843173 0.55 ENSDART00000185782
STEAP family member 2, metalloreductase
chr10_+_25219728 0.55 ENSDART00000193829
glutamate receptor, metabotropic 5a
chr16_+_4695075 0.55 ENSDART00000039054
mitochondrial trans-2-enoyl-CoA reductase
chr8_+_635704 0.55 ENSDART00000130358
chondroitin sulfate N-acetylgalactosaminyltransferase 1b
chr21_+_17956024 0.55 ENSDART00000142468
dynein, axonemal, intermediate chain 1, paralog 2
chr20_-_46128590 0.55 ENSDART00000123744
trace amine associated receptor 1b
chr7_-_7692992 0.54 ENSDART00000192619
aminoadipate aminotransferase
chr20_+_39250673 0.54 ENSDART00000153003
RALBP1 associated Eps domain containing 1
chr4_+_61995745 0.54 ENSDART00000171539

chr6_-_15492030 0.54 ENSDART00000156141
ENSDART00000183992
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of pax7a+pax7b+prop1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.7 4.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 1.6 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.5 4.3 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.4 1.8 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 1.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.4 1.8 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.4 1.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.3 1.7 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.3 3.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.0 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.3 1.6 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.3 1.4 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.2 0.9 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.2 0.6 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.2 0.8 GO:0015867 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.2 3.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.6 GO:0021611 facial nerve formation(GO:0021611)
0.2 0.6 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 0.9 GO:0002159 desmosome assembly(GO:0002159)
0.2 0.5 GO:0044406 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.2 0.5 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.1 0.7 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 0.6 GO:0015677 copper ion import(GO:0015677)
0.1 1.5 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.1 0.4 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.5 GO:0044060 regulation of endocrine process(GO:0044060) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) endocrine hormone secretion(GO:0060986)
0.1 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 1.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.9 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.8 GO:0003352 regulation of cilium movement(GO:0003352)
0.1 0.6 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.3 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 1.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.6 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 1.8 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.8 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1 1.4 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 1.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.8 GO:0098900 regulation of action potential(GO:0098900)
0.1 1.6 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.1 1.1 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 0.7 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.6 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.5 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 1.3 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 0.8 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.8 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.7 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.9 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 1.1 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 2.5 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 0.7 GO:0033198 response to ATP(GO:0033198)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.3 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.1 0.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.4 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.3 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) positive regulation of voltage-gated calcium channel activity(GO:1901387) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.1 2.2 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 2.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 0.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 1.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 2.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.5 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.2 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 1.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.0 0.6 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.3 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 1.8 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.5 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 1.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.4 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.8 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.7 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0032475 otolith formation(GO:0032475)
0.0 0.2 GO:0000097 sulfur amino acid biosynthetic process(GO:0000097)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574) lipid glycosylation(GO:0030259)
0.0 0.6 GO:0045761 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.8 GO:0006298 mismatch repair(GO:0006298)
0.0 0.7 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.7 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.6 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0045905 positive regulation of translational termination(GO:0045905)
0.0 1.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.5 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.4 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.9 GO:0042593 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 1.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0072576 liver morphogenesis(GO:0072576)
0.0 1.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.5 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 1.0 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 1.0 GO:0003146 heart jogging(GO:0003146)
0.0 1.3 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.4 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0090280 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) positive regulation of calcium ion import(GO:0090280)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 2.7 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 1.1 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.2 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 3.5 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.3 GO:0007548 sex differentiation(GO:0007548)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.0 1.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.0 GO:0070509 calcium ion import(GO:0070509)
0.0 0.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.4 1.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 0.7 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 2.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.2 0.9 GO:1902636 kinociliary basal body(GO:1902636)
0.2 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 1.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.8 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.7 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0032838 cell projection cytoplasm(GO:0032838)
0.1 1.8 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 1.4 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 2.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.7 GO:0005903 brush border(GO:0005903)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.3 GO:0043186 P granule(GO:0043186)
0.0 1.7 GO:0005861 troponin complex(GO:0005861)
0.0 1.6 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 4.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.6 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 2.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 1.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.9 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 1.2 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 15.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.6 GO:0005930 axoneme(GO:0005930)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 3.8 GO:0043005 neuron projection(GO:0043005)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 5.0 GO:0045202 synapse(GO:0045202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
1.1 4.3 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.8 3.4 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.8 2.5 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.7 2.7 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.6 4.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.5 1.6 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.5 1.5 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4 1.8 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.4 1.1 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.4 2.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 2.5 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.3 1.3 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.3 3.3 GO:0035804 structural constituent of egg coat(GO:0035804)
0.3 0.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 0.9 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.2 0.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 1.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 0.7 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.2 1.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 0.8 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.2 1.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.2 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 0.9 GO:0043295 glutathione binding(GO:0043295)
0.2 1.2 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 1.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.1 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.6 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.7 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.8 GO:0019808 polyamine binding(GO:0019808)
0.1 1.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.6 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.3 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.8 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.5 GO:0004985 opioid receptor activity(GO:0004985)
0.1 2.8 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 2.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 2.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 2.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.6 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0032138 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 1.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.7 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 2.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.6 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 4.0 GO:0003774 motor activity(GO:0003774)
0.0 1.0 GO:0042562 hormone binding(GO:0042562)
0.0 1.0 GO:0005507 copper ion binding(GO:0005507)
0.0 1.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.7 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 1.8 GO:0019904 protein domain specific binding(GO:0019904)
0.0 1.3 GO:0060090 binding, bridging(GO:0060090)
0.0 0.3 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0004527 exonuclease activity(GO:0004527)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.7 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 2.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 1.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 2.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 0.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.3 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo