Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for phox2bb

Z-value: 0.34

Motif logo

logo of

Transcription factors associated with phox2bb

Gene Symbol Gene ID Gene Info
phox2bb
ENSDARG00000091029 paired like homeobox 2Bb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
phox2bbdr11_v1_chr14_-_17072736_170727360.644.9e-12Click!

Activity profile of phox2bb motif

Sorted Z-values of phox2bb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_15433671 5.18 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr17_+_15433518 5.10 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr16_-_12173554 4.63 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr2_+_50608099 3.91 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr6_-_11768198 3.18 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr10_-_27049170 3.10 ENSDART00000143451
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr16_+_46111849 2.80 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr16_-_12173399 2.18 ENSDART00000142574
clstn3
calsyntenin 3
chr21_-_13123176 1.99 ENSDART00000144866
ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr23_+_16638639 1.89 ENSDART00000143545
snphb
syntaphilin b
chr2_+_2223837 1.53 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr5_+_60590796 1.53 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr6_+_11249706 1.26 ENSDART00000186547
ENSDART00000193287
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr3_-_48716422 1.25 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr14_-_4556896 1.25 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr4_-_1801519 1.20 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr6_+_11250316 1.16 ENSDART00000137122
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr21_+_27513859 1.14 ENSDART00000065420
pacs1a
phosphofurin acidic cluster sorting protein 1a
chr1_+_10318089 1.10 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr17_-_21418340 1.02 ENSDART00000007021
atp6v1ba
ATPase, H+ transporting, lysosomal, V1 subunit B, member a
chr14_-_470505 1.02 ENSDART00000067147
ANKRD50
ankyrin repeat domain 50
chr9_-_32177117 1.00 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr24_+_28953089 0.99 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr9_+_54039006 0.97 ENSDART00000112441
tlr7
toll-like receptor 7
chr9_-_43538328 0.96 ENSDART00000140526
znf385b
zinc finger protein 385B
chr5_+_29851433 0.93 ENSDART00000143434
ubash3ba
ubiquitin associated and SH3 domain containing Ba
chr8_-_44926077 0.91 ENSDART00000084417
timm17b
translocase of inner mitochondrial membrane 17 homolog B (yeast)
chr2_-_17393216 0.91 ENSDART00000123137
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr6_+_11250033 0.91 ENSDART00000065411
ENSDART00000132677
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr15_-_22074315 0.90 ENSDART00000149830
drd2a
dopamine receptor D2a
chr4_-_2219705 0.86 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr17_+_22577472 0.83 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr21_-_22635245 0.81 ENSDART00000115224
ENSDART00000101782
nectin1a
nectin cell adhesion molecule 1a
chr22_+_2751887 0.80 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr24_-_38657683 0.78 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr17_+_50524573 0.76 ENSDART00000187974
CR382385.1

chr15_-_14552101 0.74 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr7_+_38811800 0.74 ENSDART00000052322
zgc:110699
zgc:110699
chr1_-_15797663 0.68 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr2_-_17392799 0.54 ENSDART00000136470
ENSDART00000141188
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr17_-_16422654 0.53 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr5_+_63302660 0.46 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr23_-_2901167 0.46 ENSDART00000165955
ENSDART00000190616
zhx3
zinc fingers and homeoboxes 3
chr15_+_5360407 0.39 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr6_+_25257728 0.39 ENSDART00000162581
kyat3
kynurenine aminotransferase 3
chr1_-_31534089 0.38 ENSDART00000007770
lbx1b
ladybird homeobox 1b
chr3_-_26787430 0.36 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr22_+_508290 0.22 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr9_-_37749973 0.18 ENSDART00000087663
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr4_-_9891874 0.17 ENSDART00000067193
adm2a
adrenomedullin 2a
chr14_-_33481428 0.13 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr23_-_16485190 0.11 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr13_+_33268657 0.10 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr8_-_33381913 0.10 ENSDART00000076420
lmx1bb
LIM homeobox transcription factor 1, beta b
chr5_-_30620625 0.10 ENSDART00000098273
tcnl
transcobalamin like
chr25_-_13490744 0.05 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr6_+_40922572 0.05 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_+_3681116 0.01 ENSDART00000109618
art4
ADP-ribosyltransferase 4 (Dombrock blood group)

Network of associatons between targets according to the STRING database.

First level regulatory network of phox2bb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 1.9 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.3 3.3 GO:0044805 late nucleophagy(GO:0044805)
0.3 1.0 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 1.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.3 0.8 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.2 1.2 GO:0071543 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 1.5 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 3.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.9 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 2.8 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 1.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 1.5 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0044295 axonal growth cone(GO:0044295)
0.1 3.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 2.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 2.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 6.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.9 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 4.0 GO:0036477 somatodendritic compartment(GO:0036477)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.3 GO:0005504 fatty acid binding(GO:0005504)
0.3 0.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 1.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 1.2 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 1.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 0.5 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 1.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 1.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.1 GO:0044325 ion channel binding(GO:0044325)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair