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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for pou2f1b

Z-value: 1.07

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Transcription factors associated with pou2f1b

Gene Symbol Gene ID Gene Info
ENSDARG00000007996 POU class 2 homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f1bdr11_v1_chr9_+_34334156_34334156-0.463.5e-06Click!

Activity profile of pou2f1b motif

Sorted Z-values of pou2f1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_35458190 19.22 ENSDART00000051313
fructose-1,6-bisphosphatase 1b
chr20_+_10538025 12.60 ENSDART00000129762
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr24_+_23959487 12.27 ENSDART00000080487
homogentisate 1,2-dioxygenase
chr19_+_2835240 11.79 ENSDART00000190838
CUB domain containing protein 1
chr24_-_21150100 11.40 ENSDART00000154249
ENSDART00000193256
GRAM domain containing 1c
chr20_+_10544100 10.38 ENSDART00000113927
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_56080112 9.94 ENSDART00000075469
ENSDART00000161473
complement component c3a, duplicate 6
chr18_-_6742287 9.73 ENSDART00000140752
myo-inositol oxygenase
chr4_-_8043839 8.84 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
chr1_-_10071422 8.59 ENSDART00000135522
ENSDART00000033118
fibrinogen alpha chain
chr2_-_20120904 7.45 ENSDART00000186002
ENSDART00000124724
dihydropyrimidine dehydrogenase b
chr20_-_35750810 7.30 ENSDART00000153072
adhesion G protein-coupled receptor F8
chr2_+_27394798 7.01 ENSDART00000115071
selenoprotein P2
chr22_-_23706771 6.86 ENSDART00000159771
complement factor H like 1
chr12_+_22560067 6.86 ENSDART00000172066
polymerase (RNA) II (DNA directed) polypeptide A
chr19_-_977849 6.68 ENSDART00000172303

chr14_-_4145594 6.64 ENSDART00000077348
caspase 3, apoptosis-related cysteine peptidase b
chr4_+_5249494 6.52 ENSDART00000150391
si:ch211-214j24.14
chr12_-_4243268 6.41 ENSDART00000131275
zgc:92313
chr25_-_13029680 6.16 ENSDART00000166151
chemokine (C-C motif) ligand 39, duplicate 2
chr17_-_4231532 5.91 ENSDART00000019364
bone morphogenetic protein 2a
chr17_+_23311377 5.88 ENSDART00000128073
protein phosphatase 1, regulatory subunit 3Ca
chr15_+_14856307 5.84 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr3_+_49021079 5.58 ENSDART00000162012
zgc:163083
chr2_-_43635777 5.57 ENSDART00000148633
integrin, beta 1b.1
chr2_+_37875789 5.56 ENSDART00000036318
ENSDART00000127679
cerebellin 13
chr16_+_19637384 5.53 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr22_-_23668356 5.46 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
complement factor H
chr14_-_46198373 5.42 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr18_+_44703343 5.41 ENSDART00000131510
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, like
chr9_-_12443726 5.29 ENSDART00000102434
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr2_+_31665836 5.29 ENSDART00000135411
ENSDART00000143914
si:ch211-106h4.12
chr20_-_49889111 5.26 ENSDART00000058858
kinesin family member 13Bb
chr17_+_28102487 5.21 ENSDART00000131638
ENSDART00000076265
zgc:91908
chr3_+_12816362 5.19 ENSDART00000163743
ENSDART00000170788
cytochrome P450, family 2, subfamily K, polypeptide 6
chr1_-_44638058 5.11 ENSDART00000081835
solute carrier family 43 (amino acid system L transporter), member 1b
chr9_-_34396264 4.99 ENSDART00000045754
growth hormone regulated TBC protein 1b
chr11_-_34065718 4.98 ENSDART00000110608
collagen, type VI, alpha 1
chr2_-_21438492 4.96 ENSDART00000046098
phospholipase C, delta 1b
chr2_+_49457449 4.96 ENSDART00000185470
SH3-domain GRB2-like 1a
chr13_-_21672131 4.95 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr16_+_38394371 4.81 ENSDART00000137954
CD83 molecule
chr25_-_18454016 4.72 ENSDART00000005877
carboxypeptidase A1 (pancreatic)
chr15_+_32711663 4.65 ENSDART00000157854
ENSDART00000167515
periostin, osteoblast specific factor b
chr2_+_42191592 4.65 ENSDART00000144716
caveolae associated protein 4a
chr15_-_18209672 4.62 ENSDART00000141508
ENSDART00000136280
bloodthirsty-related gene family, member 16
chr16_-_45288599 4.56 ENSDART00000044097
hepsin
chr19_-_27570333 4.55 ENSDART00000146562
ENSDART00000179060
si:dkeyp-46h3.5
si:dkeyp-46h3.8
chr23_+_39695827 4.52 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr6_-_58764672 4.51 ENSDART00000154322
sterol O-acyltransferase 2
chr7_-_12968689 4.45 ENSDART00000173115
ENSDART00000013690
ribosomal protein, large P2, like
chr5_+_26799165 4.33 ENSDART00000145736
transcobalamin II
chr3_+_37112693 4.31 ENSDART00000055228
ENSDART00000144278
ENSDART00000138079
PSMC3 interacting protein
chr14_-_21064199 4.31 ENSDART00000172099
si:dkey-74k8.3
chr16_-_42872571 4.26 ENSDART00000154757
ENSDART00000102345
thioredoxin interacting protein b
chr23_+_7692042 4.26 ENSDART00000018512
protein O-fucosyltransferase 1
chr5_+_35458346 4.17 ENSDART00000141239
ER lipid raft associated 2
chr20_-_35578435 4.12 ENSDART00000142444
adhesion G protein-coupled receptor F6
chr16_-_23346095 4.11 ENSDART00000160546
si:dkey-247k7.2
chr3_+_49043917 4.06 ENSDART00000158212
zgc:92161
chr24_-_23758003 4.04 ENSDART00000178085
Danio rerio minichromosome maintenance domain containing 2 (mcmdc2), mRNA.
chr5_+_39087364 3.97 ENSDART00000004286
annexin A3a
chr16_+_50289916 3.95 ENSDART00000168861
ENSDART00000167332
hepcidin antimicrobial peptide
chr7_-_38792543 3.83 ENSDART00000157416
si:dkey-23n7.10
chr14_+_10461264 3.80 ENSDART00000081095
cysteinyl leukotriene receptor 1
chr19_-_340641 3.79 ENSDART00000183848
golgi phosphoprotein 3-like
chr6_+_9191981 3.77 ENSDART00000150916
zgc:112392
chr17_+_2549503 3.76 ENSDART00000156843
si:dkey-248g15.3
chr18_-_29925717 3.70 ENSDART00000099281
major histocompatibility complex class II DBB gene
chr15_+_19838458 3.69 ENSDART00000101204
activated leukocyte cell adhesion molecule b
chr20_-_39735952 3.59 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tumor protein D52-like 1
chr15_-_37867995 3.59 ENSDART00000192698
si:dkey-238d18.4
chr8_-_36287046 3.57 ENSDART00000162877
si:busm1-194e12.11
chr20_+_52492192 3.51 ENSDART00000057986
zgc:100864
chr18_-_26715156 3.44 ENSDART00000142043
MALT paracaspase 3
chr9_-_33063083 3.44 ENSDART00000048550
si:ch211-125e6.5
chr18_-_7539166 3.42 ENSDART00000133541
si:dkey-30c15.2
chr1_+_58332000 3.42 ENSDART00000145234
gamma-glutamyltransferase 1 like 2.1
chr25_+_186583 3.39 ENSDART00000161504
PCNA clamp associated factor
chr13_-_25198025 3.38 ENSDART00000159585
ENSDART00000144227
adenosine kinase a
chr19_-_1948236 3.34 ENSDART00000163344
zinc and ring finger 2a
chr1_+_7546259 3.32 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr17_-_38291065 3.31 ENSDART00000152056
paired box 9
chr20_+_18993452 3.29 ENSDART00000025509
L-threonine dehydrogenase
chr6_-_442163 3.27 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
GRB2-related adaptor protein 2b
chr18_-_26715655 3.25 ENSDART00000181497
MALT paracaspase 3
chr23_+_46183410 3.23 ENSDART00000167596
ENSDART00000151149
ENSDART00000150896
bloodthirsty-related gene family, member 31
chr22_+_29994093 3.22 ENSDART00000104778
si:dkey-286j15.3
chr10_+_34001444 3.18 ENSDART00000149934
klotho
chr10_+_35329751 3.15 ENSDART00000148043
si:dkey-259j3.5
chr1_-_23274393 3.09 ENSDART00000147800
ENSDART00000130277
ENSDART00000054340
ENSDART00000054338
ribosomal protein L9
chr21_+_8533533 3.09 ENSDART00000077924

chr12_-_20584413 3.08 ENSDART00000170923

chr17_+_16046314 3.08 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr4_-_20181964 3.07 ENSDART00000022539
fibrinogen-like 2a
chr23_-_27701361 3.02 ENSDART00000186688
ENSDART00000183985
DnaJ (Hsp40) homolog, subfamily C, member 22
chr15_-_35960250 3.02 ENSDART00000186765
collagen, type IV, alpha 4
chr21_-_34926619 3.01 ENSDART00000065337
ENSDART00000192740
kinesin family member 20A
chr19_-_27550768 3.00 ENSDART00000142313
si:dkeyp-46h3.8
chr21_+_15295685 2.99 ENSDART00000135603

chr5_-_50992690 2.97 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
3-hydroxy-3-methylglutaryl-CoA reductase a
chr23_-_13875252 2.97 ENSDART00000104834
ENSDART00000193807
glucose-6-phosphate dehydrogenase
chr11_-_29658396 2.97 ENSDART00000183947
ribosomal protein L22
chr11_+_25278772 2.97 ENSDART00000188630
cylindromatosis (turban tumor syndrome), b
chr20_-_15099579 2.95 ENSDART00000127213
flavin containing monooxygenase 5
chr23_-_37575030 2.95 ENSDART00000031875
torsin family 1 like 3
chr1_+_58922027 2.94 ENSDART00000159479
thyroid hormone receptor interactor 10b
chr1_+_9153141 2.94 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr1_+_51615672 2.92 ENSDART00000165117
zgc:165656
chr5_-_68244564 2.86 ENSDART00000169350

chr17_+_20576848 2.85 ENSDART00000183203
zgc:162183
chr4_+_76705830 2.85 ENSDART00000064312
membrane-spanning 4-domains, subfamily A, member 17A.7
chr2_+_38039857 2.85 ENSDART00000159951
calsequestrin 1a
chr1_-_55262763 2.85 ENSDART00000152769
si:ch211-286b5.4
chr21_+_19635486 2.83 ENSDART00000185736
fibroblast growth factor 10a
chr19_-_1947403 2.83 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
zinc and ring finger 2a
chr24_+_7322116 2.80 ENSDART00000005804
X-ray repair cross complementing 2
chr3_+_4403980 2.79 ENSDART00000156881

chr11_-_21404044 2.78 ENSDART00000080116
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr8_+_24745041 2.77 ENSDART00000148872
solute carrier family 16, member 4
chr7_+_20344222 2.75 ENSDART00000141186
ENSDART00000139274
plac8 onzin related protein 1
chr4_+_66853199 2.73 ENSDART00000170223
si:dkey-29m1.2
chr11_-_26576754 2.72 ENSDART00000191733
ENSDART00000002846
ST3 beta-galactoside alpha-2,3-sialyltransferase 8
chr6_+_8630355 2.72 ENSDART00000161749
ENSDART00000193976
thrombospondin-type laminin G domain and EAR repeats a
chr22_+_14836291 2.71 ENSDART00000122740
GTP binding protein 1, like
chr8_-_16515127 2.70 ENSDART00000146469
ENSDART00000132681
tetratricopeptide repeat domain 39A
chr4_-_8035520 2.70 ENSDART00000146146
si:ch211-240l19.7
chr17_-_2036850 2.67 ENSDART00000186048
ENSDART00000188838
ENSDART00000186423
serine peptidase inhibitor, Kunitz type 1 a
chr4_-_5239904 2.64 ENSDART00000190664
adenosine deaminase 2b
chr19_-_7690975 2.64 ENSDART00000151384
si:dkey-204a24.10
chr17_-_6618574 2.62 ENSDART00000184486
si:ch211-189e2.3
chr10_+_38643304 2.62 ENSDART00000067447
matrix metallopeptidase 30
chr22_-_10121880 2.62 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr25_-_13050959 2.57 ENSDART00000169041
chemokine (C-C motif) ligand 35, duplicate 1
chr24_-_12770357 2.54 ENSDART00000060826
importin 4
chr6_-_19270484 2.54 ENSDART00000186894
ENSDART00000188709
zgc:174863
chr20_-_35470891 2.53 ENSDART00000152993
ENSDART00000016090
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr6_-_38930726 2.53 ENSDART00000154151
histone deacetylase 7b
chr15_-_37767901 2.53 ENSDART00000154763
si:dkey-42l23.4
chr25_+_29474982 2.53 ENSDART00000130410
interleukin 17 receptor E-like
chr4_-_5240128 2.52 ENSDART00000144048
adenosine deaminase 2b
chr4_+_5341592 2.52 ENSDART00000123375
ENSDART00000067371
zgc:113263
chr14_-_30390145 2.48 ENSDART00000045423
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr18_+_38192499 2.48 ENSDART00000191849
nucleobindin 2b
chr1_+_32051581 2.46 ENSDART00000146602
steroid sulfatase (microsomal), isozyme S
chr11_-_21404358 2.43 ENSDART00000129062
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr20_-_29052391 2.42 ENSDART00000193482
ENSDART00000017090
thrombospondin 1b
chr23_+_32011768 2.40 ENSDART00000053509
pleiomorphic adenoma gene X
chr17_+_22530820 2.40 ENSDART00000089916
EDAR-associated death domain
chr13_+_18545819 2.39 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
chr12_-_17655683 2.39 ENSDART00000066411
discs, large (Drosophila) homolog-associated protein 5
chr15_-_23814330 2.38 ENSDART00000153843
si:ch211-167j9.5
chr1_+_32054159 2.35 ENSDART00000181442
steroid sulfatase (microsomal), isozyme S
chr23_+_43809484 2.33 ENSDART00000149534
si:ch211-149b19.3
chr18_+_39060687 2.32 ENSDART00000098729
ENSDART00000136367
zgc:171509
chr6_-_55399214 2.29 ENSDART00000168367
cathepsin A
chr20_-_41992878 2.28 ENSDART00000100967
si:dkeyp-114g9.1
chr8_-_39884359 2.27 ENSDART00000131372
malectin
chr23_-_33775145 2.26 ENSDART00000132147
ENSDART00000027959
ENSDART00000160116
Rac GTPase activating protein 1
chr3_-_45326897 2.26 ENSDART00000086417
interleukin 21 receptor, tandem duplicate 2
chr21_+_76739 2.24 ENSDART00000174654
arylsulfatase B
chr15_+_32711172 2.21 ENSDART00000163936
ENSDART00000168135
periostin, osteoblast specific factor b
chr16_-_9802449 2.21 ENSDART00000081208
TAP binding protein (tapasin)-like
chr1_-_56556326 2.19 ENSDART00000188760

chr6_-_53160459 2.18 ENSDART00000128127
solute carrier family 38, member 3b
chr18_-_3166726 2.17 ENSDART00000165002
aquaporin 11
chr9_-_33062891 2.17 ENSDART00000161182
si:ch211-125e6.5
chr25_+_22320738 2.16 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr20_+_4221978 2.14 ENSDART00000171898
interaction protein for cytohesin exchange factors 1
chr18_+_19648275 2.11 ENSDART00000100569
SMAD family member 6b
chr2_+_6253246 2.09 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr15_-_43327911 2.09 ENSDART00000077386
protease, serine, 16 (thymus)
chr10_-_40819022 2.08 ENSDART00000076316
ENSDART00000141329
zgc:113625
chr9_-_38579758 2.07 ENSDART00000131738
si:dkey-101k6.5
chr2_+_43204919 2.06 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr16_-_50229193 2.06 ENSDART00000161782
ENSDART00000010081
electron-transfer-flavoprotein, beta polypeptide
chr3_+_29476085 2.03 ENSDART00000184495
ENSDART00000181058
family with sequence similarity 83, member Fa
chr1_-_39859626 2.01 ENSDART00000053763
dCMP deaminase
chr14_-_7409364 2.01 ENSDART00000036463
DND microRNA-mediated repression inhibitor 1
chr5_-_1487256 2.00 ENSDART00000149599
ENSDART00000148411
ENSDART00000092087
ENSDART00000148464
golgin A2
chr17_-_6641535 2.00 ENSDART00000154540
ENSDART00000180384
si:ch211-189e2.3
chr10_+_26667475 1.99 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
chr5_+_50879545 1.96 ENSDART00000128402
nucleolar protein 6 (RNA-associated)
chr7_-_51102479 1.96 ENSDART00000174023
collagen, type IV, alpha 6
chr4_+_73215536 1.95 ENSDART00000174290
Danio rerio protein NLRC3-like (LOC101883187), mRNA.
chr3_+_7771420 1.94 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr21_+_25625026 1.93 ENSDART00000134678
ovo-like zinc finger 1b
chr16_+_21426524 1.92 ENSDART00000182869
gasdermin Eb
chr16_+_40508882 1.91 ENSDART00000126129
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr24_+_20372497 1.91 ENSDART00000132340
ENSDART00000139989
ENSDART00000168751
ENSDART00000192909
phospholipase C, delta 1a
chr13_+_30228077 1.91 ENSDART00000100813
ENSDART00000147729
ENSDART00000133404
ribosomal protein S24
chr10_+_29771256 1.90 ENSDART00000193195
hypoxia up-regulated 1
chr12_-_10381282 1.90 ENSDART00000152788
marker of proliferation Ki-67
chr17_-_21884323 1.90 ENSDART00000155574
CUB and zona pellucida-like domains 1, tandem duplicate 1
chr14_+_36886950 1.90 ENSDART00000183719
si:ch211-132p1.3
chr11_+_29975830 1.88 ENSDART00000148929
si:ch73-226l13.2
chr21_+_45685757 1.87 ENSDART00000160530
SEC24 homolog A, COPII coat complex component
chr5_+_32914321 1.86 ENSDART00000051336
cysteine-rich, angiogenic inducer 61 like 1
chr15_-_14038227 1.86 ENSDART00000139068
zgc:114130
chr10_+_31809226 1.86 ENSDART00000087898
forkhead box O1 b

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.2 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
2.5 7.5 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
1.7 5.2 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
1.6 4.8 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
1.5 4.6 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
1.4 4.3 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
1.2 7.0 GO:0001887 selenium compound metabolic process(GO:0001887)
1.2 5.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.0 5.2 GO:0006154 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
1.0 12.3 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.9 2.8 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.9 4.3 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.8 4.6 GO:0044209 AMP salvage(GO:0044209)
0.8 4.6 GO:0048194 Golgi vesicle budding(GO:0048194)
0.7 9.7 GO:0006020 inositol metabolic process(GO:0006020)
0.7 1.5 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839) myoblast migration(GO:0051451)
0.7 4.3 GO:0006004 fucose metabolic process(GO:0006004)
0.7 2.8 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.7 2.0 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.7 2.0 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.6 3.7 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.6 8.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.6 3.0 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.6 2.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.6 4.0 GO:0032570 response to progesterone(GO:0032570)
0.5 2.2 GO:0006867 asparagine transport(GO:0006867)
0.5 3.7 GO:0021885 forebrain cell migration(GO:0021885)
0.5 5.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.5 2.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.5 4.5 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.5 1.5 GO:1901052 sarcosine metabolic process(GO:1901052)
0.5 6.9 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.5 1.4 GO:0002188 translation reinitiation(GO:0002188)
0.5 1.8 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.5 1.4 GO:0060912 cardiac cell fate specification(GO:0060912)
0.4 1.3 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.4 1.8 GO:0006844 acyl carnitine transport(GO:0006844)
0.4 2.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.4 1.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.4 3.4 GO:0031179 peptide modification(GO:0031179)
0.4 2.5 GO:0090467 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.4 3.3 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.4 1.6 GO:0030224 monocyte differentiation(GO:0030224)
0.4 1.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.4 6.9 GO:0016203 muscle attachment(GO:0016203)
0.4 4.9 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.4 1.1 GO:0006089 lactate metabolic process(GO:0006089)
0.4 6.6 GO:0030216 keratinocyte differentiation(GO:0030216)
0.4 7.4 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.3 2.0 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.3 4.0 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.3 6.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 2.0 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.3 1.3 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.3 0.9 GO:0032640 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.3 1.1 GO:0006272 leading strand elongation(GO:0006272)
0.3 23.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.3 2.8 GO:0072078 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.2 3.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 5.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 2.1 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.2 3.4 GO:0019985 translesion synthesis(GO:0019985)
0.2 1.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 0.8 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 1.0 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.2 2.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 1.0 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.2 4.1 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2 0.6 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.2 5.7 GO:0030199 collagen fibril organization(GO:0030199)
0.2 1.7 GO:1901998 toxin transport(GO:1901998)
0.2 1.8 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.2 2.5 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.2 3.7 GO:0019882 antigen processing and presentation(GO:0019882)
0.2 3.3 GO:0060021 palate development(GO:0060021)
0.2 5.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.2 5.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 2.4 GO:0051382 kinetochore assembly(GO:0051382)
0.2 7.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 1.6 GO:0070475 rRNA base methylation(GO:0070475)
0.2 1.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.2 3.0 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.2 2.1 GO:0032094 response to food(GO:0032094)
0.1 2.8 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.1 0.4 GO:0060631 regulation of meiosis I(GO:0060631)
0.1 1.0 GO:0060343 trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.1 2.0 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 5.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.4 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 8.1 GO:0006414 translational elongation(GO:0006414)
0.1 12.2 GO:0006956 complement activation(GO:0006956)
0.1 4.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.5 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 2.1 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.2 GO:0072178 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.1 1.0 GO:0018202 histone H3-K36 methylation(GO:0010452) peptidyl-histidine modification(GO:0018202)
0.1 1.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.0 GO:0006517 protein deglycosylation(GO:0006517)
0.1 3.2 GO:0007568 aging(GO:0007568)
0.1 0.7 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 1.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.9 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 1.8 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 5.0 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.1 0.9 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.7 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 2.0 GO:0001966 thigmotaxis(GO:0001966)
0.1 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.2 GO:0042026 protein refolding(GO:0042026)
0.1 1.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.2 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1 0.5 GO:0070586 cell-cell adhesion involved in gastrulation(GO:0070586)
0.1 0.4 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.7 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.6 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 1.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.7 GO:0006032 chitin catabolic process(GO:0006032)
0.1 2.9 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 1.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 1.3 GO:1990798 pancreas regeneration(GO:1990798)
0.1 3.7 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 1.6 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 5.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.3 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 2.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 1.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 3.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.2 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 1.7 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.2 GO:0030728 ovulation(GO:0030728)
0.0 4.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.7 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 1.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.9 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 1.8 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 1.0 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 1.0 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.6 GO:0060969 nucleosome positioning(GO:0016584) negative regulation of chromatin silencing(GO:0031936) negative regulation of gene silencing(GO:0060969)
0.0 6.8 GO:0006869 lipid transport(GO:0006869)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 5.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.6 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.5 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 1.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 1.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 2.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 2.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.3 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.6 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.8 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 1.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 2.0 GO:0008033 tRNA processing(GO:0008033)
0.0 3.4 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 2.8 GO:0006954 inflammatory response(GO:0006954)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 1.3 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 1.4 GO:0034249 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 1.4 GO:0010506 regulation of autophagy(GO:0010506)
0.0 1.0 GO:0061515 myeloid cell development(GO:0061515)
0.0 16.6 GO:0006508 proteolysis(GO:0006508)
0.0 2.3 GO:0006302 double-strand break repair(GO:0006302)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.4 GO:0045087 innate immune response(GO:0045087)
0.0 2.8 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.9 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 1.9 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.9 GO:0051216 cartilage development(GO:0051216)
0.0 0.6 GO:0060326 cell chemotaxis(GO:0060326)
0.0 1.1 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.7 GO:0001503 ossification(GO:0001503)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0005577 fibrinogen complex(GO:0005577)
0.7 2.0 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.6 7.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.6 1.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 2.0 GO:0043073 germ cell nucleus(GO:0043073)
0.5 1.4 GO:0043614 multi-eIF complex(GO:0043614)
0.5 3.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 1.8 GO:0031673 H zone(GO:0031673)
0.4 2.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 1.6 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 2.0 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 2.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 1.4 GO:0070724 BMP receptor complex(GO:0070724)
0.2 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 4.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 4.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 2.4 GO:0035101 FACT complex(GO:0035101)
0.2 1.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 2.5 GO:0070187 telosome(GO:0070187)
0.1 2.1 GO:0000124 SAGA complex(GO:0000124)
0.1 4.1 GO:0035861 site of double-strand break(GO:0035861)
0.1 5.6 GO:0032587 ruffle membrane(GO:0032587)
0.1 5.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 7.1 GO:0019814 immunoglobulin complex(GO:0019814)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 2.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 8.3 GO:0005871 kinesin complex(GO:0005871)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.1 0.7 GO:0030428 cell septum(GO:0030428)
0.1 4.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.2 GO:0071564 npBAF complex(GO:0071564)
0.1 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 4.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 3.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.9 GO:0048179 activin receptor complex(GO:0048179)
0.1 87.0 GO:0005615 extracellular space(GO:0005615)
0.1 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 2.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 7.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.7 GO:0030496 midbody(GO:0030496)
0.1 5.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 9.3 GO:0005840 ribosome(GO:0005840)
0.0 4.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 25.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 5.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 2.0 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0005880 nuclear microtubule(GO:0005880)
0.0 2.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 1.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 4.3 GO:0009986 cell surface(GO:0009986)
0.0 0.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.8 5.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
1.5 7.5 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
1.4 7.0 GO:0008430 selenium binding(GO:0008430)
1.1 4.5 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
1.1 5.6 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
1.0 3.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.0 4.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.9 4.6 GO:0004001 adenosine kinase activity(GO:0004001)
0.9 6.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.8 9.7 GO:0008199 ferric iron binding(GO:0008199)
0.8 5.5 GO:0004974 leukotriene receptor activity(GO:0004974)
0.7 2.2 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.7 3.3 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.6 5.9 GO:0070700 BMP receptor binding(GO:0070700)
0.5 1.6 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.5 4.3 GO:0031419 cobalamin binding(GO:0031419)
0.5 6.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.4 1.8 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.4 1.7 GO:0004925 prolactin receptor activity(GO:0004925)
0.4 7.3 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.4 3.4 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.4 3.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.4 1.5 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.4 2.2 GO:0015182 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.4 2.5 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.3 3.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 6.7 GO:0004875 complement receptor activity(GO:0004875)
0.3 6.6 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.3 4.0 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.3 2.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 4.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.3 0.8 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.3 4.1 GO:2001069 glycogen binding(GO:2001069)
0.3 3.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 1.8 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 5.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 1.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 6.9 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.3 4.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.2 12.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 5.0 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 2.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 4.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 2.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 24.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 2.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 3.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 4.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 9.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.2 1.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 3.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 2.9 GO:0019894 kinesin binding(GO:0019894)
0.1 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 8.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 2.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.1 4.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.3 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.7 GO:0004100 chitin synthase activity(GO:0004100)
0.1 3.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.0 GO:0019239 deaminase activity(GO:0019239)
0.1 1.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 2.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 2.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 4.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 3.0 GO:0050661 NADP binding(GO:0050661)
0.1 8.3 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.9 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 12.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.7 GO:0015926 glucosidase activity(GO:0015926)
0.1 1.3 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.4 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 3.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 4.9 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.7 GO:0004568 chitinase activity(GO:0004568)
0.1 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.3 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 2.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 9.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 2.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.0 GO:0098631 protein binding involved in cell adhesion(GO:0098631)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 5.4 GO:0000149 SNARE binding(GO:0000149)
0.0 1.3 GO:0008009 chemokine activity(GO:0008009)
0.0 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 2.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 5.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.9 GO:0008201 heparin binding(GO:0008201)
0.0 1.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 4.3 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 2.2 GO:0003774 motor activity(GO:0003774)
0.0 1.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.7 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 10.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 10.0 NABA COLLAGENS Genes encoding collagen proteins
0.2 3.7 PID CONE PATHWAY Visual signal transduction: Cones
0.2 7.9 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.5 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.1 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.3 PID AURORA B PATHWAY Aurora B signaling
0.1 4.9 PID E2F PATHWAY E2F transcription factor network
0.1 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 5.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.8 8.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 7.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.5 7.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.4 5.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.4 3.8 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 5.3 REACTOME KINESINS Genes involved in Kinesins
0.2 8.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 2.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 3.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2 2.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 1.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 7.2 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.2 3.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 10.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 3.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.2 3.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 1.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 8.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 3.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 11.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 2.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.1 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 4.5 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors