Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for pou5f3

Z-value: 0.62

Motif logo

logo of

Transcription factors associated with pou5f3

Gene Symbol Gene ID Gene Info
pou5f3
ENSDARG00000044774 POU domain, class 5, transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou5f3dr11_v1_chr21_-_13690712_13690712-0.205.6e-02Click!

Activity profile of pou5f3 motif

Sorted Z-values of pou5f3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_34868814 10.96 ENSDART00000153049
stmn4
stathmin-like 4
chr4_-_5302162 8.57 ENSDART00000177099
SNAP91 (1 of many)
si:ch211-214j24.9
chr22_+_5106751 8.31 ENSDART00000138967
atcaya
ataxia, cerebellar, Cayman type a
chr7_+_61050329 8.08 ENSDART00000115355
nwd2
NACHT and WD repeat domain containing 2
chr1_-_40994259 7.75 ENSDART00000101562
adra2c
adrenoceptor alpha 2C
chr19_-_43552252 6.86 ENSDART00000138308
gpr186
G protein-coupled receptor 186
chr4_-_8903240 6.65 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr24_-_21989406 5.80 ENSDART00000032963
apoob
apolipoprotein O, b
chr24_-_20641000 5.79 ENSDART00000166135
zbtb47b
zinc finger and BTB domain containing 47b
chr8_-_16592491 5.21 ENSDART00000101655
calr
calreticulin
chr13_-_39830999 4.79 ENSDART00000115089
zgc:171482
zgc:171482
chr21_+_39361040 4.71 ENSDART00000085453
cluhb
clustered mitochondria (cluA/CLU1) homolog b
chr24_+_17007407 3.93 ENSDART00000110652
zfx
zinc finger protein, X-linked
chr22_+_16535575 3.45 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr25_+_26923193 3.43 ENSDART00000187364
grm8b
glutamate receptor, metabotropic 8b
chr11_-_36001495 3.23 ENSDART00000190330
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b
chr11_+_7528599 2.60 ENSDART00000171813
adgrl2a
adhesion G protein-coupled receptor L2a
chr24_-_7321928 2.59 ENSDART00000167570
ENSDART00000045150
actr3b
ARP3 actin related protein 3 homolog B
chr22_+_15507218 2.51 ENSDART00000125450
gpc1a
glypican 1a
chr16_-_31351419 2.11 ENSDART00000178298
ENSDART00000018091
mroh1
maestro heat-like repeat family member 1
chr8_+_43016714 1.96 ENSDART00000142671
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr9_+_12444494 1.65 ENSDART00000102430
tmem41aa
transmembrane protein 41aa
chr7_-_72155022 1.50 ENSDART00000187984
zmp:0000001168
zmp:0000001168
chr8_+_7740004 1.45 ENSDART00000170184
ENSDART00000187811
fgd1
FYVE, RhoGEF and PH domain containing 1
chr8_-_22698651 1.35 ENSDART00000181411
iqsec2a
IQ motif and Sec7 domain 2a
chr13_+_31172833 1.22 ENSDART00000176378
CR931802.3

chr24_-_25004553 1.22 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr9_-_2945008 1.18 ENSDART00000183452
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr25_-_15040369 1.07 ENSDART00000159342
ENSDART00000166490
pax6a
paired box 6a
chr8_-_44238526 0.99 ENSDART00000061115
ENSDART00000132473
ENSDART00000138019
ENSDART00000133021
piwil1
piwi-like RNA-mediated gene silencing 1
chr7_+_58843700 0.97 ENSDART00000159500
ENSDART00000158436
lypla1
lysophospholipase I
chr18_+_7543347 0.93 ENSDART00000103467
arf5
ADP-ribosylation factor 5
chr7_-_24644893 0.71 ENSDART00000048921
rgp1
GP1 homolog, RAB6A GEF complex partner 1
chr24_+_3328354 0.70 ENSDART00000147468
bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr23_-_33709964 0.59 ENSDART00000143333
ENSDART00000130338
pou6f1
POU class 6 homeobox 1
chr10_+_20628698 0.37 ENSDART00000064666
prnpb
prion protein b
chr13_+_18545819 0.26 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
zgc:154058
chr22_-_30881738 0.15 ENSDART00000059965
si:dkey-49n23.1
si:dkey-49n23.1
chr15_-_23206562 0.11 ENSDART00000110360
ccdc153
coiled-coil domain containing 153
chr11_+_19060278 0.02 ENSDART00000164294
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of pou5f3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.7 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
1.1 3.4 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.8 8.3 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.4 4.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.4 5.8 GO:0042407 cristae formation(GO:0042407)
0.2 11.0 GO:1902749 microtubule depolymerization(GO:0007019) regulation of cell cycle G2/M phase transition(GO:1902749)
0.2 1.0 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 1.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 5.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 2.0 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 3.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 2.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 3.2 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.0 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 2.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.5 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 9.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.8 GO:0061617 MICOS complex(GO:0061617)
0.1 2.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.2 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 5.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.0 GO:0043186 P granule(GO:0043186)
0.0 11.7 GO:0043005 neuron projection(GO:0043005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.7 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.8 8.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.5 3.4 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.3 3.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.0 GO:0034584 piRNA binding(GO:0034584)
0.1 2.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 5.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 11.0 GO:0015631 tubulin binding(GO:0015631)
0.0 4.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 9.5 GO:0004930 G-protein coupled receptor activity(GO:0004930)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.0 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK