Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for pou6f1

Z-value: 0.95

Motif logo

logo of

Transcription factors associated with pou6f1

Gene Symbol Gene ID Gene Info
pou6f1
ENSDARG00000011570 POU class 6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou6f1dr11_v1_chr23_-_33709964_337100290.651.8e-12Click!

Activity profile of pou6f1 motif

Sorted Z-values of pou6f1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_50770537 21.21 ENSDART00000158723
sncb
synuclein, beta
chr15_-_16098531 20.75 ENSDART00000080377
aldoca
aldolase C, fructose-bisphosphate, a
chr4_+_12615836 17.14 ENSDART00000003583
lmo3
LIM domain only 3
chr4_+_22365061 14.90 ENSDART00000039277
lhfpl3
LHFPL tetraspan subfamily member 3
chr18_-_1185772 14.09 ENSDART00000143245
nptnb
neuroplastin b
chr7_+_38717624 13.77 ENSDART00000132522
syt13
synaptotagmin XIII
chr5_+_64732270 13.15 ENSDART00000134241
olfm1a
olfactomedin 1a
chr19_+_30662529 12.84 ENSDART00000175662
fam49al
family with sequence similarity 49, member A-like
chr3_-_28250722 12.42 ENSDART00000165936
rbfox1
RNA binding fox-1 homolog 1
chr11_+_39672874 10.90 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr19_-_5103313 10.15 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr11_-_7320211 9.61 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr21_-_26918901 9.03 ENSDART00000100685
lrfn4a
leucine rich repeat and fibronectin type III domain containing 4a
chr17_+_12698532 7.43 ENSDART00000064509
ENSDART00000136830
stmn4l
stathmin-like 4, like
chr24_-_32408404 7.38 ENSDART00000144157
si:ch211-56a11.2
si:ch211-56a11.2
chr22_-_11829436 7.25 ENSDART00000126784
ptpn4b
protein tyrosine phosphatase, non-receptor type 4b
chr4_-_19028861 7.24 ENSDART00000166374
si:dkey-31f5.11
si:dkey-31f5.11
chr12_+_18681477 7.07 ENSDART00000127981
ENSDART00000143979
rgs9b
regulator of G protein signaling 9b
chr24_+_41931585 6.81 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr6_+_3004972 6.45 ENSDART00000186750
ENSDART00000183862
ENSDART00000191485
ENSDART00000171014
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr22_-_15385442 6.40 ENSDART00000090975
tmem264
transmembrane protein 264
chr9_+_11034314 6.07 ENSDART00000032695
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr14_-_31465905 6.07 ENSDART00000173108
gpc3
glypican 3
chr22_+_16535575 5.74 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr13_-_21701323 5.68 ENSDART00000164112
si:dkey-191g9.7
si:dkey-191g9.7
chr9_+_41612642 5.65 ENSDART00000138473
spegb
SPEG complex locus b
chr2_-_12243213 5.60 ENSDART00000113081
gpr158b
G protein-coupled receptor 158b
chr3_+_33341640 5.48 ENSDART00000186352
pyya
peptide YYa
chr22_+_2830703 5.42 ENSDART00000145463
ENSDART00000144785
si:dkey-20i20.8
si:dkey-20i20.8
chr2_+_29249204 5.40 ENSDART00000168957
cdh18a
cadherin 18, type 2a
chr12_+_32729470 5.32 ENSDART00000175712
rbfox3a
RNA binding fox-1 homolog 3a
chr1_+_25801648 5.30 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr21_+_25231160 5.27 ENSDART00000063089
ENSDART00000139127
gng8
guanine nucleotide binding protein (G protein), gamma 8
chr19_-_31402429 5.10 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr22_+_2793382 5.10 ENSDART00000144980
si:dkey-20i20.8
si:dkey-20i20.8
chr24_-_21404367 4.92 ENSDART00000152093
atp8a2
ATPase phospholipid transporting 8A2
chr19_-_9503473 4.91 ENSDART00000091615
iffo1a
intermediate filament family orphan 1a
chr16_-_5154024 4.64 ENSDART00000132069
ENSDART00000060635
dctn3
dynactin 3 (p22)
chr13_+_22119798 4.45 ENSDART00000173206
ENSDART00000078652
ENSDART00000165842
camk2g2
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2
chr17_+_22072337 4.27 ENSDART00000063716
ENSDART00000141684
nphp1
nephronophthisis 1
chr13_+_43400443 4.21 ENSDART00000084321
dact2
dishevelled-binding antagonist of beta-catenin 2
chr22_-_10019768 4.17 ENSDART00000162077
BX324216.2

chr5_-_35953472 4.10 ENSDART00000143448
rxfp2l
relaxin/insulin-like family peptide receptor 2, like
chr11_+_29770966 4.06 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr2_+_9552456 4.05 ENSDART00000056896
dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_-_21288202 4.05 ENSDART00000191766
ENSDART00000187319
fam171a2a
family with sequence similarity 171, member A2a
chr1_-_57280585 3.90 ENSDART00000152220
si:dkey-27j5.5
si:dkey-27j5.5
chr6_-_17849786 3.81 ENSDART00000172709
rptor
regulatory associated protein of MTOR, complex 1
chr4_+_14826299 3.76 ENSDART00000067035
shisal1a
shisa like 1a
chr24_+_14595680 3.72 ENSDART00000137337
ENSDART00000091784
ENSDART00000136026
thtpa
thiamine triphosphatase
chr2_-_48966431 3.69 ENSDART00000147948
kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr17_-_45150763 3.63 ENSDART00000155043
ENSDART00000156786
ENSDART00000191147
tmed8
transmembrane p24 trafficking protein 8
chr19_-_8600383 3.52 ENSDART00000081546
trim46b
tripartite motif containing 46b
chr15_+_24704798 3.48 ENSDART00000192470
LRRC75A
si:dkey-151p21.7
chr4_-_18202291 3.39 ENSDART00000169704
anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr25_-_20666328 3.15 ENSDART00000098076
csk
C-terminal Src kinase
chr8_-_10961991 2.84 ENSDART00000139603
trim33
tripartite motif containing 33
chr14_+_46003973 2.70 ENSDART00000145241
ENSDART00000141545
slu7
SLU7 homolog, splicing factor
chr9_-_6624663 2.64 ENSDART00000092537
GPR45
si:dkeyp-118h3.5
chr19_+_46222918 2.55 ENSDART00000158703
vps28
vacuolar protein sorting 28 (yeast)
chr16_-_24044664 2.53 ENSDART00000136982
bcam
basal cell adhesion molecule (Lutheran blood group)
chr9_-_14504834 2.40 ENSDART00000056103
nrp2b
neuropilin 2b
chr19_+_46222428 2.26 ENSDART00000183984
vps28
vacuolar protein sorting 28 (yeast)
chr4_+_25431990 2.19 ENSDART00000176982
prkcq
protein kinase C, theta
chr13_+_3938526 2.17 ENSDART00000012759
yipf3
Yip1 domain family, member 3
chr11_+_21587950 2.15 ENSDART00000162251
FAM72B
zgc:101564
chr2_-_50372467 2.13 ENSDART00000108900
cntnap2b
contactin associated protein like 2b
chr9_-_38036984 2.10 ENSDART00000134574
hacd2
3-hydroxyacyl-CoA dehydratase 2
chr25_-_20666754 2.09 ENSDART00000158418
csk
C-terminal Src kinase
chr7_-_19364813 2.08 ENSDART00000173977
ntn4
netrin 4
chr22_+_1462997 2.05 ENSDART00000157476
si:dkeyp-53d3.5
si:dkeyp-53d3.5
chr9_-_32672129 1.90 ENSDART00000140581
gzm3.4
granzyme 3, tandem duplicate 4
chr19_+_42469058 1.77 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr17_-_49438873 1.76 ENSDART00000004424
znf292a
zinc finger protein 292a
chr7_+_44715224 1.75 ENSDART00000184630
si:dkey-56m19.5
si:dkey-56m19.5
chr5_-_39736383 1.73 ENSDART00000127123
rasgef1ba
RasGEF domain family, member 1Ba
chr22_+_2504524 1.71 ENSDART00000136686
znf1170
zinc finger protein 1170
chr7_+_53498152 1.55 ENSDART00000184497
znf609b
zinc finger protein 609b
chr18_+_34181655 1.54 ENSDART00000130831
ENSDART00000109535
gmps
guanine monophosphate synthase
chr13_-_24825691 1.49 ENSDART00000142745
slka
STE20-like kinase a
chr7_+_48297842 1.48 ENSDART00000052123
slc25a44b
solute carrier family 25, member 44 b
chr15_-_931815 1.47 ENSDART00000106627
ENSDART00000102239
ENSDART00000184754
ENSDART00000186733
zgc:162936
zgc:162936
chr16_-_25368048 1.41 ENSDART00000132445
rbfa
ribosome binding factor A
chr20_+_22067337 1.38 ENSDART00000152636
clocka
clock circadian regulator a
chr3_-_33935200 1.29 ENSDART00000151211
gtf2f1
general transcription factor IIF, polypeptide 1
chr7_-_9803154 1.29 ENSDART00000055593
aldh1a3
aldehyde dehydrogenase 1 family, member A3
chr15_-_33640890 1.28 ENSDART00000167705
stard13b
StAR-related lipid transfer (START) domain containing 13b
chr2_-_27619954 1.27 ENSDART00000144826
tgs1
trimethylguanosine synthase 1
chr18_+_3243292 1.14 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr8_-_7474997 1.14 ENSDART00000146555
gata1b
GATA binding protein 1b
chr1_+_19649545 1.12 ENSDART00000054575
tmem192
transmembrane protein 192
chr23_+_41912151 1.11 ENSDART00000191115
podn
podocan
chr25_+_37480285 1.03 ENSDART00000166187
CABZ01095001.1

chr17_-_49443399 1.02 ENSDART00000155293
cga
glycoprotein hormones, alpha polypeptide
chr15_-_33172246 0.97 ENSDART00000158666
nbeab
neurobeachin b
chr1_+_33634186 0.91 ENSDART00000075626
htr1fb
5-hydroxytryptamine (serotonin) receptor 1Fb
chr3_+_57038033 0.88 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr14_+_44804326 0.88 ENSDART00000079866
ENSDART00000172974
slc30a9
solute carrier family 30 (zinc transporter), member 9
chr6_-_29105727 0.81 ENSDART00000184355
fam69ab
family with sequence similarity 69, member Ab
chr11_-_14813029 0.81 ENSDART00000004920
ENSDART00000122645
sgta
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr2_-_57941037 0.72 ENSDART00000131420
si:dkeyp-68b7.5
si:dkeyp-68b7.5
chr23_+_45860676 0.67 ENSDART00000012234
syap1
synapse associated protein 1
chr15_-_5720583 0.66 ENSDART00000158034
ENSDART00000190332
ENSDART00000109599
urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr12_-_22509069 0.52 ENSDART00000179755
ENSDART00000109707
neurl4
neuralized E3 ubiquitin protein ligase 4
chr11_-_26180714 0.52 ENSDART00000173597
kaznb
kazrin, periplakin interacting protein b
chr4_-_72609118 0.46 ENSDART00000174077
si:cabz01054396.2
si:cabz01054396.2
chr12_+_34854562 0.46 ENSDART00000130366
si:dkey-21c1.4
si:dkey-21c1.4
chr22_-_11520405 0.44 ENSDART00000063157
slc26a11
solute carrier family 26 (anion exchanger), member 11
chr13_-_5965423 0.42 ENSDART00000144931
actr2b
ARP2 actin related protein 2b homolog
chr4_-_72609735 0.39 ENSDART00000174299
ENSDART00000159227
si:cabz01054394.6
si:cabz01054394.6
chr21_-_22547496 0.28 ENSDART00000166835
ENSDART00000089030
myo5b
myosin VB
chr25_-_8625601 0.22 ENSDART00000155280
GDPGP1
zgc:153343
chr21_-_40938382 0.22 ENSDART00000008593
yipf5
Yip1 domain family, member 5
chr3_-_33934788 0.19 ENSDART00000151411
gtf2f1
general transcription factor IIF, polypeptide 1
chr7_-_22941472 0.18 ENSDART00000190334
tnfsf10l
TNF superfamily member 10, like
chr1_-_51710225 0.16 ENSDART00000057601
ENSDART00000152745
snrpb2
small nuclear ribonucleoprotein polypeptide B2
chr11_+_11303458 0.13 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
si:dkey-23f9.4
chr24_-_16979728 0.11 ENSDART00000005331
klhl15
kelch-like family member 15
chr24_+_22485710 0.02 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr25_-_1333676 0.02 ENSDART00000183182
ENSDART00000188907
cln6b
CLN6, transmembrane ER protein b

Network of associatons between targets according to the STRING database.

First level regulatory network of pou6f1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.1 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.9 5.7 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
1.5 13.1 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
1.3 5.3 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
1.0 5.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.9 20.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8 21.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.8 9.6 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.8 6.1 GO:0060976 coronary vasculature development(GO:0060976)
0.8 6.8 GO:1904861 excitatory synapse assembly(GO:1904861)
0.7 6.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.7 4.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.6 3.7 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.5 4.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.5 14.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.4 2.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.4 2.4 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.4 4.1 GO:0046548 retinal rod cell development(GO:0046548)
0.4 2.8 GO:0048569 post-embryonic organ development(GO:0048569)
0.3 1.0 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
0.3 4.1 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.3 5.1 GO:0032418 lysosome localization(GO:0032418)
0.3 13.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 12.4 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.3 0.8 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.2 0.7 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.2 7.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 5.5 GO:0007631 feeding behavior(GO:0007631)
0.2 1.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 7.4 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.2 1.5 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 4.9 GO:0045332 phospholipid translocation(GO:0045332)
0.1 4.3 GO:0001736 establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.1 13.3 GO:0007605 sensory perception of sound(GO:0007605)
0.1 4.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 4.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 3.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 3.8 GO:0030307 positive regulation of cell growth(GO:0030307) TORC1 signaling(GO:0038202) cellular response to amino acid stimulus(GO:0071230)
0.1 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 2.1 GO:0030497 fatty acid elongation(GO:0030497)
0.1 2.1 GO:0070831 basement membrane assembly(GO:0070831)
0.1 1.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 3.7 GO:0010107 potassium ion import(GO:0010107) potassium ion import across plasma membrane(GO:1990573)
0.1 5.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.4 GO:2001032 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 4.5 GO:0001666 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293)
0.0 1.4 GO:0009648 photoperiodism(GO:0009648)
0.0 0.9 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) serotonin receptor signaling pathway(GO:0007210)
0.0 0.9 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.0 7.3 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 3.5 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.4 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 2.9 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 2.2 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.5 21.2 GO:0043679 axon terminus(GO:0043679)
0.5 3.8 GO:0031931 TORC1 complex(GO:0031931)
0.3 4.6 GO:0005869 dynactin complex(GO:0005869)
0.3 4.8 GO:0000813 ESCRT I complex(GO:0000813)
0.3 1.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.3 2.2 GO:0001772 immunological synapse(GO:0001772)
0.3 5.6 GO:0031430 M band(GO:0031430)
0.3 0.8 GO:0072380 TRC complex(GO:0072380)
0.3 2.1 GO:0033010 paranodal junction(GO:0033010)
0.3 6.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 3.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 27.9 GO:0030424 axon(GO:0030424)
0.1 2.1 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 4.5 GO:0016342 catenin complex(GO:0016342)
0.1 5.1 GO:0031902 late endosome membrane(GO:0031902)
0.1 7.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 3.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.9 GO:0005882 intermediate filament(GO:0005882)
0.0 5.7 GO:0045177 apical part of cell(GO:0045177)
0.0 13.1 GO:0045202 synapse(GO:0045202)
0.0 0.5 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 2.7 GO:0016607 nuclear speck(GO:0016607)
0.0 12.8 GO:0043005 neuron projection(GO:0043005)
0.0 3.1 GO:0005911 cell-cell junction(GO:0005911)
0.0 2.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.2 GO:1903136 cuprous ion binding(GO:1903136)
2.6 20.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.5 10.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
1.1 5.5 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.9 3.7 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.8 7.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.5 2.1 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.5 6.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.4 14.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 3.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 1.5 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.3 5.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 13.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 2.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 2.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 1.4 GO:0070888 E-box binding(GO:0070888)
0.2 9.6 GO:0008013 beta-catenin binding(GO:0008013)
0.2 3.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 3.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 4.1 GO:0051087 chaperone binding(GO:0051087)
0.1 4.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 2.2 GO:0010857 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 13.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 5.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.8 GO:0030674 protein binding, bridging(GO:0030674)
0.1 17.7 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 4.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.9 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 4.9 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.2 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 10.9 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.4 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 7.4 GO:0015631 tubulin binding(GO:0015631)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 5.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.8 PID LKB1 PATHWAY LKB1 signaling events
0.1 6.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.4 6.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.4 4.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 3.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.4 7.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 1.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 4.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 4.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 4.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 3.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins