Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for pparaa+pparda+ppardb

Z-value: 0.85

Motif logo

logo of

Transcription factors associated with pparaa+pparda+ppardb

Gene Symbol Gene ID Gene Info
ppardb
ENSDARG00000009473 peroxisome proliferator-activated receptor delta b
pparaa
ENSDARG00000031777 peroxisome proliferator-activated receptor alpha a
pparda
ENSDARG00000044525 peroxisome proliferator-activated receptor delta a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ppardbdr11_v1_chr8_+_23711842_23711842-0.312.5e-03Click!
pparaadr11_v1_chr4_-_18635005_18635005-0.213.8e-02Click!
ppardadr11_v1_chr22_+_1006573_1006573-0.103.2e-01Click!

Activity profile of pparaa+pparda+ppardb motif

Sorted Z-values of pparaa+pparda+ppardb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_11201096 11.64 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr7_+_34297271 9.30 ENSDART00000180342
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr6_-_39764995 9.28 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr6_-_39765546 8.86 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr21_-_19006631 8.02 ENSDART00000080269
ENSDART00000191682
pgam2
phosphoglycerate mutase 2 (muscle)
chr9_-_43082945 7.58 ENSDART00000142257
ccdc141
coiled-coil domain containing 141
chr7_+_34296789 7.07 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_+_7043634 6.59 ENSDART00000133954
mhc1uka
major histocompatibility complex class I UKA
chr3_+_27770110 6.06 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr20_+_15015557 5.34 ENSDART00000039345
myoc
myocilin
chr10_+_35417099 5.21 ENSDART00000063398
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr20_+_47953047 5.02 ENSDART00000079734
hadhaa
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
chr17_-_32370047 4.79 ENSDART00000145487
klf11b
Kruppel-like factor 11b
chr23_+_17417539 4.61 ENSDART00000182605
BX649300.2

chr14_-_48103207 4.58 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr21_+_15704556 4.37 ENSDART00000024858
ENSDART00000146909
chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr20_-_47953524 4.26 ENSDART00000167986
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr15_+_404891 4.13 ENSDART00000155682
nipsnap2
nipsnap homolog 2
chr18_-_48508585 3.82 ENSDART00000133364
kcnj1a.4
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr1_+_40802454 3.72 ENSDART00000193568
cpz
carboxypeptidase Z
chr5_-_30984010 3.36 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr6_+_60036767 3.34 ENSDART00000155009
tgm8
transglutaminase 8
chr19_+_40861853 3.33 ENSDART00000126470
zgc:85777
zgc:85777
chr19_+_2631565 3.29 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr8_+_999421 3.27 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr16_-_50229193 3.19 ENSDART00000161782
ENSDART00000010081
etfb
electron-transfer-flavoprotein, beta polypeptide
chr7_-_24046999 3.15 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr3_-_34561624 3.10 ENSDART00000129313
sept9a
septin 9a
chr14_-_29826659 3.07 ENSDART00000138413
sorbs2b
sorbin and SH3 domain containing 2b
chr3_+_30257582 2.92 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
mybpc2a
myosin binding protein C, fast type a
chr20_-_34164278 2.78 ENSDART00000153128
hmcn1
hemicentin 1
chr18_-_48517040 2.77 ENSDART00000143645
kcnj1a.3
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr17_+_30546579 2.70 ENSDART00000154385
nhsl1a
NHS-like 1a
chr3_+_58167288 2.66 ENSDART00000155874
ENSDART00000010395
uqcrc2a
ubiquinol-cytochrome c reductase core protein 2a
chr8_-_2529878 2.64 ENSDART00000056767
acaa2
acetyl-CoA acyltransferase 2
chr22_-_7050 2.47 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr3_-_18805225 2.46 ENSDART00000133471
ENSDART00000131758
msrb1a
methionine sulfoxide reductase B1a
chr20_+_43379029 2.33 ENSDART00000142486
ENSDART00000186486
unc93a
unc-93 homolog A
chr22_+_22888 2.30 ENSDART00000082471
mfap2
microfibril associated protein 2
chr22_+_18469004 2.29 ENSDART00000061430
cilp2
cartilage intermediate layer protein 2
chr17_+_30545895 2.28 ENSDART00000076739
nhsl1a
NHS-like 1a
chr24_+_2961098 2.26 ENSDART00000163760
ENSDART00000170835
eci2
enoyl-CoA delta isomerase 2
chr13_+_9842276 2.26 ENSDART00000041700
ENSDART00000141406
prdx3
peroxiredoxin 3
chr15_+_28268135 2.21 ENSDART00000152536
ENSDART00000188550
myo1cb
myosin Ic, paralog b
chr24_+_81527 2.20 ENSDART00000192139
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr18_+_13315739 2.15 ENSDART00000143404
si:ch211-260p9.3
si:ch211-260p9.3
chr16_-_30563129 2.11 ENSDART00000191716
lmna
lamin A
chr23_-_39636195 2.07 ENSDART00000144439
vwa1
von Willebrand factor A domain containing 1
chr3_-_53486169 2.07 ENSDART00000115243
soul5
heme-binding protein soul5
chr1_-_17797802 2.07 ENSDART00000041215
sorbs2a
sorbin and SH3 domain containing 2a
chr10_+_11265387 1.95 ENSDART00000038888
hsdl2
hydroxysteroid dehydrogenase like 2
chr19_-_7043355 1.90 ENSDART00000104845
tapbp.1
TAP binding protein (tapasin), tandem duplicate 1
chr1_+_58139102 1.90 ENSDART00000134826
si:ch211-15j1.4
si:ch211-15j1.4
chr8_-_979735 1.88 ENSDART00000149612
znf366
zinc finger protein 366
chr1_-_52292235 1.82 ENSDART00000132638
si:dkey-121b10.7
si:dkey-121b10.7
chr9_+_41224100 1.81 ENSDART00000141792
stat1b
signal transducer and activator of transcription 1b
chr2_-_26476030 1.77 ENSDART00000145262
ENSDART00000132125
acadm
acyl-CoA dehydrogenase medium chain
chr9_+_30626416 1.74 ENSDART00000147813
tbc1d4
TBC1 domain family, member 4
chr18_+_16744307 1.73 ENSDART00000179872
ENSDART00000133490
lyve1b
lymphatic vessel endothelial hyaluronic receptor 1b
chr20_-_48604199 1.62 ENSDART00000161762
ENSDART00000170894
mgst3a
microsomal glutathione S-transferase 3a
chr23_-_16737161 1.61 ENSDART00000132573
si:ch211-224l10.4
si:ch211-224l10.4
chr20_-_26937453 1.60 ENSDART00000139756
ftr97
finTRIM family, member 97
chr15_+_31820536 1.58 ENSDART00000045921
frya
furry homolog a (Drosophila)
chr8_+_2530065 1.57 ENSDART00000063943
mrpl40
mitochondrial ribosomal protein L40
chr5_-_30984271 1.54 ENSDART00000051392
spns3
spinster homolog 3 (Drosophila)
chr12_-_684200 1.54 ENSDART00000152122
si:ch211-176g6.2
si:ch211-176g6.2
chr5_+_43870389 1.50 ENSDART00000141002
zgc:112966
zgc:112966
chr7_+_48675347 1.47 ENSDART00000157917
ENSDART00000185580
trpm5
transient receptor potential cation channel, subfamily M, member 5
chr20_-_48604621 1.46 ENSDART00000161769
ENSDART00000157871
mgst3a
microsomal glutathione S-transferase 3a
chr11_-_6974022 1.38 ENSDART00000172851
COMP
si:ch211-43f4.1
chr15_-_6946286 1.35 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr5_-_66301142 1.33 ENSDART00000067541
prlrb
prolactin receptor b
chr1_-_58868306 1.33 ENSDART00000166615
dnm2b
dynamin 2b
chr25_+_5288665 1.32 ENSDART00000169540
CABZ01039861.1

chr24_+_9590188 1.29 ENSDART00000137092
si:dkey-96n2.1
si:dkey-96n2.1
chr23_-_16734009 1.24 ENSDART00000125449
si:ch211-224l10.4
si:ch211-224l10.4
chr17_-_12196865 1.24 ENSDART00000154694
kif28
kinesin family member 28
chr20_-_26936887 1.23 ENSDART00000160827
ftr79
finTRIM family, member 79
chr3_-_58116314 1.22 ENSDART00000154901
si:ch211-256e16.6
si:ch211-256e16.6
chr1_+_57050899 1.16 ENSDART00000152601
si:ch211-1f22.14
si:ch211-1f22.14
chr1_+_58353661 1.12 ENSDART00000140074
si:dkey-222h21.2
si:dkey-222h21.2
chr1_-_35113974 1.12 ENSDART00000192811
ENSDART00000167461
BX897691.1

chr4_+_60492313 1.12 ENSDART00000191043
ENSDART00000191631
si:dkey-211i20.2
si:dkey-211i20.2
chr1_-_46859398 1.11 ENSDART00000135795
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr7_+_17356482 1.09 ENSDART00000063629
nitr3r.1l
novel immune-type receptor 3, related 1-like
chr1_+_58260886 1.05 ENSDART00000110453
si:dkey-222h21.8
si:dkey-222h21.8
chr8_-_20291922 1.02 ENSDART00000148304
myo1f
myosin IF
chr21_+_26720803 0.99 ENSDART00000053797
slc3a2b
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr5_-_323712 0.98 ENSDART00000188793
HOOK3
hook microtubule tethering protein 3
chr18_+_27926839 0.91 ENSDART00000191835
hipk3b
homeodomain interacting protein kinase 3b
chr3_+_1179601 0.82 ENSDART00000173378
triobpb
TRIO and F-actin binding protein b
chr7_+_11459235 0.78 ENSDART00000159611
il16
interleukin 16
chr11_+_45153104 0.75 ENSDART00000159204
ENSDART00000177585
tk1
thymidine kinase 1, soluble
chr2_+_7213146 0.75 ENSDART00000191134
ENSDART00000146547
si:ch211-13f8.2
si:ch211-13f8.2
chr5_-_41875834 0.71 ENSDART00000133592
si:dkey-65b12.10
si:dkey-65b12.10
chr25_+_36347126 0.71 ENSDART00000152449
si:ch211-113a14.22
si:ch211-113a14.22
chr22_+_9287929 0.70 ENSDART00000193522
si:ch211-250k18.7
si:ch211-250k18.7
chr9_-_1939232 0.70 ENSDART00000146131
hoxd3a
homeobox D3a
chr4_+_75577480 0.68 ENSDART00000188196
si:ch211-227e10.1
si:ch211-227e10.1
chr22_+_9114416 0.67 ENSDART00000190169
nlrp15
NACHT, LRR and PYD domains-containing protein 15
chr17_+_6538733 0.66 ENSDART00000193712
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr3_+_32546499 0.66 ENSDART00000151739
pax10
paired box 10
chr4_+_33547662 0.66 ENSDART00000150439
si:dkey-84h14.2
si:dkey-84h14.2
chr13_+_43050562 0.65 ENSDART00000016602
cdh23
cadherin-related 23
chr17_-_20711735 0.62 ENSDART00000150056
ank3b
ankyrin 3b
chr4_-_991043 0.60 ENSDART00000184706
naga
N-acetylgalactosaminidase, alpha
chr4_-_36032177 0.59 ENSDART00000170143
zgc:174180
zgc:174180
chr22_+_9239831 0.58 ENSDART00000133720
si:ch211-250k18.5
si:ch211-250k18.5
chr4_-_50926767 0.56 ENSDART00000183430
si:ch211-208f21.3
si:ch211-208f21.3
chr22_+_10163901 0.55 ENSDART00000190468
rpp14
ribonuclease P/MRP 14 subunit
chr22_-_10774735 0.55 ENSDART00000081156
timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr14_+_24258562 0.52 ENSDART00000106074
ENSDART00000173227
chrm1a
cholinergic receptor, muscarinic 1a
chr23_-_24488696 0.51 ENSDART00000155593
tmem82
transmembrane protein 82
chr25_-_35113891 0.50 ENSDART00000190724
zgc:165555
zgc:165555
chr8_-_8698607 0.50 ENSDART00000046712
zgc:86609
zgc:86609
chr13_+_829585 0.48 ENSDART00000029051
gsta.2
glutathione S-transferase, alpha tandem duplicate 2
chr7_+_23940933 0.46 ENSDART00000173628
si:dkey-183c6.7
si:dkey-183c6.7
chr16_-_25680666 0.41 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr1_+_58442694 0.39 ENSDART00000160897
zgc:194906
zgc:194906
chr7_+_17353030 0.38 ENSDART00000098020
si:busm1-169i8.11
si:busm1-169i8.11
chr2_-_56649883 0.37 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr15_+_45640906 0.36 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr13_-_28688104 0.36 ENSDART00000133827
pcgf6
polycomb group ring finger 6
chr18_-_3456117 0.34 ENSDART00000158508
myo7aa
myosin VIIAa
chr10_-_44027391 0.33 ENSDART00000145404
crybb1
crystallin, beta B1
chr6_-_35046735 0.32 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr22_-_38274188 0.31 ENSDART00000139420
ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr6_-_28117995 0.30 ENSDART00000147253
si:ch73-194h10.3
si:ch73-194h10.3
chr15_-_12500938 0.28 ENSDART00000159627
scn4ba
sodium channel, voltage-gated, type IV, beta a
chr20_+_46286082 0.27 ENSDART00000073519
taar14f
trace amine associated receptor 14f
chr12_-_5120175 0.24 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr11_-_44999858 0.21 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr19_+_32158010 0.20 ENSDART00000005255
mrpl53
mitochondrial ribosomal protein L53
chr9_+_32069989 0.19 ENSDART00000139540
si:dkey-83m22.7
si:dkey-83m22.7
chr12_-_44199316 0.17 ENSDART00000170378
si:ch73-329n5.1
si:ch73-329n5.1
chr22_+_9069081 0.16 ENSDART00000187842
BX248395.1

chr5_+_38200807 0.15 ENSDART00000100769
hsd20b2
hydroxysteroid (20-beta) dehydrogenase 2
chr5_-_36549024 0.14 ENSDART00000097671
zgc:158432
zgc:158432
chr23_+_44634187 0.13 ENSDART00000143688
si:ch73-265d7.2
si:ch73-265d7.2
chr15_+_17030941 0.12 ENSDART00000062069
plin2
perilipin 2
chr12_+_26670778 0.11 ENSDART00000144355
arhgap12b
Rho GTPase activating protein 12b
chr4_-_16451375 0.10 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr2_-_42960353 0.09 ENSDART00000098303
oc90
otoconin 90
chr20_-_38836161 0.07 ENSDART00000061358
si:dkey-221h15.4
si:dkey-221h15.4
chr5_-_41860556 0.03 ENSDART00000140154
si:dkey-65b12.12
si:dkey-65b12.12

Network of associatons between targets according to the STRING database.

First level regulatory network of pparaa+pparda+ppardb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 16.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.6 18.1 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.7 2.2 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.5 5.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.4 15.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.4 2.1 GO:0090342 regulation of cell aging(GO:0090342)
0.3 1.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.3 1.0 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.3 5.3 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.3 8.0 GO:0007520 myoblast fusion(GO:0007520)
0.2 0.7 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 1.9 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 0.7 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 7.6 GO:0019226 transmission of nerve impulse(GO:0019226)
0.2 3.3 GO:0018149 peptide cross-linking(GO:0018149)
0.2 0.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 1.8 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 1.5 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.7 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 4.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.6 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 2.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 6.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 1.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884) neurotransmitter receptor internalization(GO:0099590)
0.1 2.8 GO:0071711 basement membrane organization(GO:0071711)
0.1 3.6 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 2.2 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.1 4.6 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 11.3 GO:0006936 muscle contraction(GO:0006936)
0.0 1.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 3.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.8 GO:0050930 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 3.1 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.4 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:0034633 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 2.3 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 3.7 GO:0016485 protein processing(GO:0016485)
0.0 0.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 4.0 GO:0006869 lipid transport(GO:0006869)
0.0 6.4 GO:0007015 actin filament organization(GO:0007015)
0.0 1.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.2 GO:0006334 nucleosome assembly(GO:0006334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 18.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 11.6 GO:0031430 M band(GO:0031430)
0.6 2.2 GO:1990909 Wnt signalosome(GO:1990909)
0.2 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 5.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 4.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 3.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 11.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 3.6 GO:0005902 microvillus(GO:0005902)
0.0 13.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 27.1 GO:0005739 mitochondrion(GO:0005739)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 1.6 GO:0030427 site of polarized growth(GO:0030427)
0.0 2.7 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 1.7 GO:0044420 extracellular matrix component(GO:0044420)
0.0 3.1 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.7 5.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
1.6 18.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.6 8.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
1.5 4.6 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
1.2 6.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.9 2.6 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.6 2.5 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.5 6.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 5.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 1.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.3 2.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 1.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.6 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.2 0.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 2.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 3.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.7 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 3.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 0.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 1.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 3.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.7 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 2.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.4 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 3.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.3 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 2.2 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 3.2 GO:0009055 electron carrier activity(GO:0009055)
0.0 1.5 GO:0051020 GTPase binding(GO:0051020)
0.0 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 11.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.2 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 3.1 GO:0060090 binding, bridging(GO:0060090)
0.0 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.1 GO:0020037 heme binding(GO:0020037)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 10.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.1 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 8.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 7.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 16.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import