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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for rbpja

Z-value: 0.93

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Transcription factors associated with rbpja

Gene Symbol Gene ID Gene Info
ENSDARG00000003398 recombination signal binding protein for immunoglobulin kappa J region a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rbpjadr11_v1_chr1_+_14454663_14454663-0.056.2e-01Click!

Activity profile of rbpja motif

Sorted Z-values of rbpja motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_4331117 12.46 ENSDART00000008893
carbonic anhydrase XVa
chr22_-_237651 9.68 ENSDART00000075210
zgc:66156
chr1_+_1805294 9.31 ENSDART00000103850
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3
chr3_-_3209432 8.83 ENSDART00000140635
si:ch211-229i14.2
chr14_+_51098036 8.80 ENSDART00000184118

chr3_+_26081343 8.79 ENSDART00000134647
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr17_+_24851951 8.18 ENSDART00000180746
connexin 35.4
chr19_-_5332784 6.81 ENSDART00000010373
keratin, type 1, gene 19d
chr10_-_20357013 6.42 ENSDART00000080143
secreted frizzled-related protein 1b
chr7_-_3429874 6.41 ENSDART00000132330
si:ch211-285c6.1
chr6_+_45932276 6.11 ENSDART00000103491
retinol binding protein 7b, cellular
chr23_+_1730663 6.06 ENSDART00000149545
transglutaminase 1, K polypeptide
chr23_-_27571667 6.02 ENSDART00000008174
phosphofructokinase, muscle a
chr9_-_40765868 5.76 ENSDART00000138634
ATP-binding cassette, sub-family A (ABC1), member 12
chr2_-_20923864 5.72 ENSDART00000006870
prostaglandin-endoperoxide synthase 2a
chr18_-_46241775 5.40 ENSDART00000145999
ENSDART00000134244
ENSDART00000185021
ENSDART00000181855
periaxin
chr16_-_45094599 5.37 ENSDART00000155479
si:rp71-77l1.1
chr17_+_16046132 5.18 ENSDART00000155005
si:ch73-204p21.2
chr25_-_18470695 4.77 ENSDART00000034377
carboxypeptidase A5
chr20_+_3934516 4.72 ENSDART00000165732
C-type lectin domain containing 11A
chr4_-_20043484 4.61 ENSDART00000167780
zgc:193726
chr21_-_27213166 4.53 ENSDART00000146959
MAP/microtubule affinity-regulating kinase 2a
chr3_-_31254379 4.39 ENSDART00000189376
actinoporin-like protein
chr17_+_33433576 4.13 ENSDART00000077581
synaptosomal-associated protein 23.2
chr20_-_8110672 4.00 ENSDART00000113993
si:ch211-232i5.1
chr10_-_25816558 3.93 ENSDART00000017240
periostin, osteoblast specific factor a
chr5_-_37900350 3.81 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
transmembrane protease, serine 13b
chr2_-_30324610 3.80 ENSDART00000185422
junctophilin 1b
chr23_+_19790962 3.79 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr16_+_41974438 3.75 ENSDART00000102771
si:ch211-225p5.8
chr20_+_218886 3.73 ENSDART00000002661
laminin, alpha 4
chr15_-_31147301 3.63 ENSDART00000157145
ENSDART00000155473
ENSDART00000048103
kinase suppressor of ras 1b
chr9_-_56399699 3.61 ENSDART00000170281
RAB3 GTPase activating protein subunit 1
chr25_+_245018 3.60 ENSDART00000155344
zgc:92481
chr16_-_44945224 3.60 ENSDART00000156921
neural cell adhesion molecule 3
chr3_-_53092509 3.59 ENSDART00000062081
lysophosphatidic acid receptor 2a
chr18_-_5209258 3.53 ENSDART00000183109

chr2_-_30324297 3.44 ENSDART00000099078
junctophilin 1b
chr4_+_55778679 3.43 ENSDART00000183009

chr4_+_55794876 3.43 ENSDART00000189043

chr4_+_55810436 3.43 ENSDART00000182875

chr4_-_68568233 3.42 ENSDART00000184284

chr3_+_36646054 3.40 ENSDART00000170013
ENSDART00000159948
G1 to S phase transition 1, like
chr19_+_38422059 3.34 ENSDART00000035093
procollagen, type IX, alpha 2
chr14_+_26229056 3.31 ENSDART00000179045

chr16_+_2905150 3.21 ENSDART00000109980
leucyl-tRNA synthetase 2, mitochondrial
chr16_+_26449615 3.18 ENSDART00000039746
erythrocyte membrane protein band 4.1b
chr21_-_22720381 3.12 ENSDART00000130789
complement component 1, q subcomponent, C chain
chr3_+_4213864 3.12 ENSDART00000059613
si:dkeyp-52c3.5
chr2_-_32237916 3.07 ENSDART00000141418
family with sequence similarity 49, member Ba
chr25_+_20272145 3.01 ENSDART00000109605
si:dkey-219c3.2
chr13_-_34781984 3.01 ENSDART00000172138
isthmin 1
chr7_+_49681040 3.00 ENSDART00000176372
ENSDART00000192172
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr3_+_2669813 3.00 ENSDART00000014205

chr4_-_74028161 3.00 ENSDART00000174062

chr23_-_32092443 2.96 ENSDART00000133688
LETM1 domain containing 1
chr10_-_342564 2.95 ENSDART00000157633
vasodilator stimulated phosphoprotein a
chr17_-_2573021 2.94 ENSDART00000074181
zona pellucida glycoprotein 3, tandem duplicate 2
chr16_-_24605969 2.94 ENSDART00000163305
ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr20_+_23501535 2.90 ENSDART00000177922
ENSDART00000058532
palladin, cytoskeletal associated protein
chr5_-_6567464 2.90 ENSDART00000184985
tankyrase 1 binding protein 1
chr12_-_30548244 2.87 ENSDART00000193616
zgc:158404
chr25_+_34915762 2.86 ENSDART00000191776
syntrophin, beta 2
chr6_-_9695294 2.83 ENSDART00000162728
NOP58 ribonucleoprotein homolog (yeast)
chr23_-_5783421 2.79 ENSDART00000131521
ENSDART00000019455
cysteine and glycine-rich protein 1a
chr19_-_18127808 2.76 ENSDART00000108627
sorting nexin 10a
chr20_+_53368611 2.73 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr25_+_245438 2.71 ENSDART00000004689
zgc:92481
chr19_+_42609132 2.69 ENSDART00000010104
cartilage associated protein
chr19_+_48018802 2.65 ENSDART00000161339
ENSDART00000166978
si:ch1073-205c8.3
chr22_-_506522 2.57 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr20_-_39596338 2.41 ENSDART00000023531
hes-related family bHLH transcription factor with YRPW motif 2
chr1_-_54100988 2.39 ENSDART00000192662
regulatory factor X, 1b (influences HLA class II expression)
chr19_+_43341424 2.36 ENSDART00000134815
sestrin 2
chr18_-_18937485 2.35 ENSDART00000139015
si:dkey-73n10.1
chr11_+_13159988 2.30 ENSDART00000064176
MOB kinase activator 3C
chr5_+_36850650 2.26 ENSDART00000051186
non-specific cytotoxic cell receptor protein 1
chr7_+_2236317 2.25 ENSDART00000075859
zgc:172065
chr10_+_38512270 2.18 ENSDART00000109752
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr20_-_49657134 2.17 ENSDART00000151248
collagen, type XII, alpha 1b
chr2_+_8112449 2.17 ENSDART00000138136
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a
chr20_+_39283849 2.13 ENSDART00000002481
ENSDART00000146683
scavenger receptor class A, member 3
chr19_-_18127629 2.13 ENSDART00000187722
sorting nexin 10a
chr19_-_12648122 2.12 ENSDART00000151184
family with sequence similarity 210, member Aa
chr1_+_52690448 2.12 ENSDART00000150326
oxysterol binding protein
chr4_+_21741228 2.11 ENSDART00000112035
ENSDART00000127664
myogenic factor 5
chr24_+_7884880 2.10 ENSDART00000139467
bone morphogenetic protein 6
chr19_-_42462491 2.08 ENSDART00000131715
proteasome subunit beta 4
chr10_-_44306636 2.08 ENSDART00000191068
cyclin dependent kinase 2 associated protein 1
chr4_-_76183357 2.08 ENSDART00000181362
ENSDART00000150331
si:ch211-106j21.4
zgc:110171
chr16_-_17300030 2.07 ENSDART00000149267
Kell blood group, metallo-endopeptidase
chr10_-_44306399 2.07 ENSDART00000180042
cyclin dependent kinase 2 associated protein 1
chr3_+_3641429 2.03 ENSDART00000092393
phospholipase B domain containing 1
chr18_-_21746421 2.02 ENSDART00000188809
protein serine kinase H1
chr5_-_32338866 2.01 ENSDART00000017956
ENSDART00000047670
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr11_-_22361306 2.00 ENSDART00000180688
ENSDART00000182200
ENSDART00000006580
transcription factor EB
chr16_-_25680666 1.96 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr16_-_30885838 1.96 ENSDART00000131356
DENN/MADD domain containing 3b
chr22_-_164944 1.95 ENSDART00000145379
filamin binding LIM protein 1
chr12_-_46959990 1.91 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr10_-_38468847 1.90 ENSDART00000133914
glycerophosphodiester phosphodiesterase domain containing 5a
chr19_+_3842891 1.86 ENSDART00000159043
LSM10, U7 small nuclear RNA associated
chr8_-_46386024 1.79 ENSDART00000136602
ENSDART00000060919
ENSDART00000137472
glutaminyl-tRNA synthetase
chr24_-_9989634 1.74 ENSDART00000115275
zgc:152652
chr21_+_45268112 1.70 ENSDART00000157136
transcription factor 7
chr21_+_20549395 1.68 ENSDART00000181633
ephrin-A5a
chr5_-_47727819 1.64 ENSDART00000165249
cytochrome c oxidase, subunit VIIc
chr1_-_51720633 1.64 ENSDART00000045894
ribonuclease H2, subunit A
chr12_+_9542124 1.64 ENSDART00000127952
prolyl 4-hydroxylase, alpha polypeptide I a
chr4_-_39484284 1.62 ENSDART00000129216
si:dkey-261o4.6
chr16_+_9762261 1.61 ENSDART00000020654
proteasome 26S subunit, non-ATPase 4b
chr5_+_9246458 1.60 ENSDART00000081772
sushi domain containing 1
chr3_+_17616201 1.58 ENSDART00000156775
RAB5C, member RAS oncogene family
chr11_-_16394971 1.58 ENSDART00000180981
ENSDART00000179925
leucine-rich repeats and immunoglobulin-like domains 1
chr13_+_674351 1.55 ENSDART00000111328
cutC copper transporter homolog (E. coli)
chr13_-_49819027 1.52 ENSDART00000067824
beta-1,3-N-acetylgalactosaminyltransferase 2
chr16_-_32233463 1.52 ENSDART00000102016
calcium homeostasis modulator family member 6
chr12_+_7399403 1.50 ENSDART00000103526
BicC family RNA binding protein 1b
chr17_+_5061135 1.50 ENSDART00000064313
CDC5 cell division cycle 5-like (S. pombe)
chr14_+_32926385 1.47 ENSDART00000139159
ligand of numb-protein X 2b
chr24_-_21090447 1.45 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
queuine tRNA-ribosyltransferase accessory subunit 2
chr24_-_37877978 1.45 ENSDART00000128574
transmembrane protein 204
chr18_-_50676567 1.43 ENSDART00000172264
ubiquitin-conjugating enzyme E2Q family member 1
chr23_+_17839187 1.40 ENSDART00000104647
DNA primase subunit 1
chr24_+_35933869 1.40 ENSDART00000173322
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr20_+_14789148 1.39 ENSDART00000164761
transmembrane p24 trafficking protein 5
chr2_-_50053006 1.39 ENSDART00000083654
si:ch211-106n13.3
chr5_-_17876709 1.38 ENSDART00000141978
si:dkey-112e17.1
chr15_-_28908027 1.37 ENSDART00000182790
ENSDART00000192461
echinoderm microtubule associated protein like 2
chr1_-_23370395 1.36 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
PDS5 cohesin associated factor A
chr3_-_3428938 1.33 ENSDART00000179811
ENSDART00000115282
ENSDART00000192263
ENSDART00000046454
zgc:171445
chr16_-_30901159 1.32 ENSDART00000180313
DENN/MADD domain containing 3b
chr20_-_3911546 1.26 ENSDART00000169787
cnksr family member 3
chr14_+_13454840 1.25 ENSDART00000161854
plastin 3 (T isoform)
chr7_+_65564163 1.25 ENSDART00000082679
microtubule associated monooxygenase, calponin and LIM domain containing 2a
chr8_+_36554816 1.25 ENSDART00000126687
splicing factor 3a, subunit 1
chr7_-_5125799 1.23 ENSDART00000173390
leukotriene B4 receptor 2a
chr12_-_35054354 1.22 ENSDART00000075351
zgc:112285
chr10_+_31951338 1.22 ENSDART00000019416
LHFPL tetraspan subfamily member 6
chr14_-_4321874 1.21 ENSDART00000042672
GUF1 homolog, GTPase
chr19_+_48018464 1.19 ENSDART00000172307
ENSDART00000163848
si:ch1073-205c8.3
chr15_-_28907709 1.16 ENSDART00000017268
echinoderm microtubule associated protein like 2
chr4_-_74367912 1.14 ENSDART00000174199
ENSDART00000165257
protein tyrosine phosphatase, receptor type, b
chr25_+_1549838 1.14 ENSDART00000115001
arginine vasopressin receptor 1Aa
chr12_+_25223843 1.13 ENSDART00000077180
ENSDART00000127454
ENSDART00000122665
metastasis associated 1 family, member 3
chr10_+_573667 1.09 ENSDART00000110384
SMAD family member 4a
chr24_-_37877554 1.08 ENSDART00000132219
transmembrane protein 204
chr2_+_3201345 1.07 ENSDART00000130349
wingless-type MMTV integration site family, member 9A
chr21_-_37194365 1.06 ENSDART00000100286
fibroblast growth factor receptor 4
chr3_-_3439150 1.05 ENSDART00000021286
si:dkey-46g23.5
chr7_+_3558030 1.00 ENSDART00000158322
si:dkey-192d15.1
chr2_-_59247811 1.00 ENSDART00000141384
finTRIM family, member 32
chr6_-_36552844 0.99 ENSDART00000023613
hairy-related 6
chr7_+_54475134 0.96 ENSDART00000164063
zgc:153993
chr17_+_11372531 0.96 ENSDART00000130975
ENSDART00000149366
translocase of inner mitochondrial membrane 9 homolog
chr24_-_25184553 0.96 ENSDART00000166917
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr24_+_39027481 0.95 ENSDART00000085565
calpain 15
chr4_+_45441669 0.94 ENSDART00000150745
si:ch211-162i8.7
chr4_+_74943111 0.94 ENSDART00000004739
nucleoporin 50
chr10_-_39091894 0.92 ENSDART00000184505
immunoglobulin superfamily, member 5a
chr22_-_26274177 0.91 ENSDART00000060978
WD repeat domain containing 83
chr5_-_57641257 0.91 ENSDART00000149282
heat shock protein, alpha-crystallin-related, b2
chr3_+_31058464 0.87 ENSDART00000153381
si:dkey-66i24.7
chr20_+_14789305 0.87 ENSDART00000002463
transmembrane p24 trafficking protein 5
chr1_-_46981134 0.84 ENSDART00000130607
pbx/knotted 1 homeobox 1.2
chr20_-_33961697 0.82 ENSDART00000061765
selectin P
chr10_-_10864331 0.77 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr18_-_18587745 0.77 ENSDART00000191973
splicing factor 3b, subunit 3
chr18_-_46369516 0.75 ENSDART00000018163
interferon regulatory factor 2 binding protein 1
chr20_-_54508650 0.71 ENSDART00000147642

chr13_+_21919786 0.70 ENSDART00000182440
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a
chr19_+_41520892 0.68 ENSDART00000182218
ENSDART00000115123
CREB regulated transcription coactivator 2
chr4_-_65210616 0.67 ENSDART00000183988
ENSDART00000186858
ENSDART00000185740
si:dkey-14o6.1
chr2_-_898899 0.67 ENSDART00000058289
dual specificity phosphatase 22b
chr23_-_24047054 0.66 ENSDART00000184308
ENSDART00000185902

chr18_-_17075098 0.66 ENSDART00000042496
ENSDART00000192284
ENSDART00000180307
transport and golgi organization 6 homolog (Drosophila)
chr3_+_27722355 0.62 ENSDART00000132761
Rho GDP dissociation inhibitor (GDI) gamma
chr2_-_55317035 0.59 ENSDART00000169382
ENSDART00000097874
tropomyosin 4b
chr21_-_22831388 0.57 ENSDART00000151040
angiopoietin-like 5
chr6_-_59388625 0.57 ENSDART00000111992
protein phosphatase 1, regulatory subunit 16B
chr25_+_2263857 0.57 ENSDART00000076439
tyrosyl-tRNA synthetase 2, mitochondrial
chr17_-_6508406 0.53 ENSDART00000002778
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr10_-_10863936 0.53 ENSDART00000180568
NOTCH regulated ankyrin repeat protein a
chr25_+_16646113 0.50 ENSDART00000110426
cat eye syndrome chromosome region, candidate 2
chr19_+_10536093 0.50 ENSDART00000138706
si:dkey-211g8.1
chr22_-_3255341 0.50 ENSDART00000114232
G protein-coupled receptor 35, tandem duplicate 1
chr7_+_15329819 0.49 ENSDART00000006018
mesoderm posterior aa
chr25_+_34915576 0.48 ENSDART00000073441
syntrophin, beta 2
chr7_+_39054478 0.47 ENSDART00000173825
diacylglycerol kinase, zeta a
chr6_+_58522738 0.46 ENSDART00000157327
ADP-ribosylation factor related protein 1
chr2_-_38287987 0.43 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
chr2_-_41518340 0.42 ENSDART00000130830
otolith matrix protein
chr8_+_16726386 0.40 ENSDART00000144621
small integral membrane protein 15
chr7_+_61184104 0.39 ENSDART00000110671
zgc:194930
chr7_+_19495379 0.38 ENSDART00000180514
si:ch211-212k18.8
chr13_-_50546634 0.37 ENSDART00000192127

chr10_+_39091353 0.37 ENSDART00000125986
si:ch73-1a9.4
chr19_-_24218942 0.37 ENSDART00000189198

chr14_+_109016 0.37 ENSDART00000158405
glypican 2
chr7_+_24496894 0.37 ENSDART00000149994
negative elongation factor complex member A

Network of associatons between targets according to the STRING database.

First level regulatory network of rbpja

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
1.4 5.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.1 12.5 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.0 4.9 GO:0070986 left/right axis specification(GO:0070986)
0.8 2.4 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.8 5.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.7 4.4 GO:0051818 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.7 5.8 GO:0048730 epidermis morphogenesis(GO:0048730)
0.7 3.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.7 2.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.7 3.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.5 6.0 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.5 3.7 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.5 9.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.4 1.7 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.4 1.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.4 1.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 2.4 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.3 2.6 GO:0060036 notochord cell vacuolation(GO:0060036)
0.3 6.1 GO:0018149 peptide cross-linking(GO:0018149)
0.3 1.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 2.0 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.2 1.9 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2 3.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 1.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 3.7 GO:0016203 muscle attachment(GO:0016203)
0.2 4.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 3.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 3.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.2 3.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.2 1.6 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 4.1 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.8 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 2.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 6.4 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.1 1.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 3.0 GO:0001843 neural tube closure(GO:0001843)
0.1 1.0 GO:0021794 thalamus development(GO:0021794)
0.1 2.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.6 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1 2.2 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 2.0 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 2.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.7 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 1.0 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.1 3.1 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 2.9 GO:2000649 regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 2.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 2.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.4 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 2.8 GO:0045214 sarcomere organization(GO:0045214)
0.0 3.1 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 3.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.5 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.2 GO:0070293 renal absorption(GO:0070293)
0.0 4.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 4.7 GO:0001503 ossification(GO:0001503)
0.0 9.4 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.4 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.6 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.4 GO:0032098 regulation of appetite(GO:0032098)
0.0 1.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 2.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0060037 pharyngeal system development(GO:0060037)
0.0 3.0 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 1.7 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 1.1 GO:0051028 mRNA transport(GO:0051028)
0.0 1.4 GO:0030239 myofibril assembly(GO:0030239)
0.0 7.1 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 3.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.4 GO:0006826 iron ion transport(GO:0006826)
0.0 4.1 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.2 GO:0008380 RNA splicing(GO:0008380)
0.0 3.2 GO:0006869 lipid transport(GO:0006869)
0.0 0.7 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.9 GO:0006400 tRNA modification(GO:0006400)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0031673 H zone(GO:0031673)
1.5 4.4 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.4 7.2 GO:0030314 junctional membrane complex(GO:0030314)
0.7 3.4 GO:0018444 translation release factor complex(GO:0018444)
0.6 1.7 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.5 6.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.5 2.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.5 1.4 GO:1990077 primosome complex(GO:1990077)
0.4 1.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 2.4 GO:0061700 GATOR2 complex(GO:0061700)
0.2 2.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 3.7 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 1.5 GO:0000974 Prp19 complex(GO:0000974)
0.2 3.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 3.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 3.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 2.0 GO:0005686 U2 snRNP(GO:0005686)
0.1 2.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 9.7 GO:0016459 myosin complex(GO:0016459)
0.1 2.1 GO:0005839 proteasome core complex(GO:0005839)
0.1 6.9 GO:0005581 collagen trimer(GO:0005581)
0.1 1.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 1.4 GO:0031430 M band(GO:0031430)
0.1 1.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 12.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.5 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.4 GO:0032021 NELF complex(GO:0032021)
0.0 4.0 GO:0005882 intermediate filament(GO:0005882)
0.0 2.8 GO:0030018 Z disc(GO:0030018)
0.0 2.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.6 GO:0031201 SNARE complex(GO:0031201)
0.0 8.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 5.2 GO:0009986 cell surface(GO:0009986)
0.0 2.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 4.8 GO:0010008 endosome membrane(GO:0010008)
0.0 2.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 3.7 GO:0030425 dendrite(GO:0030425) somatodendritic compartment(GO:0036477)
0.0 0.4 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.9 9.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.7 3.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 6.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.5 8.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.5 2.0 GO:0031005 filamin binding(GO:0031005)
0.5 1.9 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.5 3.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.4 12.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 3.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 2.4 GO:0070728 leucine binding(GO:0070728)
0.3 6.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 3.0 GO:0005522 profilin binding(GO:0005522)
0.3 2.9 GO:0035804 structural constituent of egg coat(GO:0035804)
0.3 3.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 2.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 1.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 2.1 GO:0070700 BMP receptor binding(GO:0070700)
0.2 1.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.2 4.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 6.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 1.9 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 1.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 2.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 4.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.8 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 3.0 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.6 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 2.8 GO:0030515 snoRNA binding(GO:0030515)
0.1 2.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 4.9 GO:0005518 collagen binding(GO:0005518)
0.1 1.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 2.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 2.8 GO:0042805 actinin binding(GO:0042805)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 4.2 GO:0043022 ribosome binding(GO:0043022)
0.1 1.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 2.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.4 GO:0032190 acrosin binding(GO:0032190)
0.1 2.0 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 3.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 5.8 GO:0005319 lipid transporter activity(GO:0005319)
0.1 1.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 5.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 4.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 9.7 GO:0003774 motor activity(GO:0003774)
0.0 1.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.0 4.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 12.7 GO:0005525 GTP binding(GO:0005525)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.8 GO:0008083 growth factor activity(GO:0008083)
0.0 2.9 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 1.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.6 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 3.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 8.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.1 PID BMP PATHWAY BMP receptor signaling
0.1 1.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 3.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 4.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.5 5.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 8.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 2.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 3.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 5.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 2.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 1.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 6.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.7 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1 2.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 1.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 5.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.6 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer