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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for rbpjb

Z-value: 0.82

Motif logo

Transcription factors associated with rbpjb

Gene Symbol Gene ID Gene Info
ENSDARG00000052091 recombination signal binding protein for immunoglobulin kappa J region b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rbpjbdr11_v1_chr7_+_62080456_620804560.075.3e-01Click!

Activity profile of rbpjb motif

Sorted Z-values of rbpjb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_31891110 11.68 ENSDART00000173883
myosin binding protein C, cardiac
chr17_-_25326685 8.06 ENSDART00000082327
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr17_-_25326296 7.15 ENSDART00000168822
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr10_+_22782522 6.63 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
chr25_-_23526058 5.09 ENSDART00000191331
ENSDART00000062930
pleckstrin homology-like domain, family A, member 2
chr20_-_39596338 4.88 ENSDART00000023531
hes-related family bHLH transcription factor with YRPW motif 2
chr11_-_11518469 4.79 ENSDART00000104254
keratin 15
chr3_-_36839115 4.25 ENSDART00000154553
receptor (G protein-coupled) activity modifying protein 2
chr22_+_16308806 3.96 ENSDART00000162685
leucine rich repeat containing 39
chr22_+_16308450 3.96 ENSDART00000105678
leucine rich repeat containing 39
chr2_-_898899 3.59 ENSDART00000058289
dual specificity phosphatase 22b
chr19_+_42609132 3.57 ENSDART00000010104
cartilage associated protein
chr25_+_6122823 3.55 ENSDART00000191824
ENSDART00000067514
RNA binding protein with multiple splicing 2a
chr19_-_25113660 3.39 ENSDART00000035538
protein tyrosine phosphatase type IVA, member 3
chr16_-_42523744 3.32 ENSDART00000017185
T-box 20
chr3_+_41917499 3.21 ENSDART00000028673
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr15_-_37846047 3.11 ENSDART00000184837
heat shock cognate 70
chr2_-_44746723 3.09 ENSDART00000041806
acyl-CoA synthetase medium chain family member 3
chr4_-_9722568 3.07 ENSDART00000067190
tetraspanin 9b
chr6_-_36552844 2.95 ENSDART00000023613
hairy-related 6
chr5_-_69312533 2.84 ENSDART00000082614
ENSDART00000183098
smoothelin b
chr23_-_23401305 2.75 ENSDART00000078936
hairy-related 9
chr21_-_27213166 2.74 ENSDART00000146959
MAP/microtubule affinity-regulating kinase 2a
chr24_-_6375774 2.69 ENSDART00000013294
annexin A13
chr1_-_45633955 2.62 ENSDART00000044057
septin 3
chr5_+_23151169 2.46 ENSDART00000125638
T-box 5b
chr20_+_39283849 2.45 ENSDART00000002481
ENSDART00000146683
scavenger receptor class A, member 3
chr9_+_38684871 2.35 ENSDART00000147938
ENSDART00000004462
heart development protein with EGF-like domains 1
chr22_+_30335936 2.33 ENSDART00000059923
max interactor 1, dimerization protein
chr24_-_37877743 2.14 ENSDART00000105658
transmembrane protein 204
chr7_+_27834130 2.04 ENSDART00000052656
RAS related 2
chr6_+_45932276 2.03 ENSDART00000103491
retinol binding protein 7b, cellular
chr5_-_47727819 2.03 ENSDART00000165249
cytochrome c oxidase, subunit VIIc
chr19_-_31802296 1.93 ENSDART00000103640
hes-related family bHLH transcription factor with YRPW motif 1
chr13_+_30804367 1.89 ENSDART00000053946
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr13_+_33246150 1.89 ENSDART00000136356
ENSDART00000132834
ENSDART00000144379
ENSDART00000131985
ENSDART00000148368
ENSDART00000035940
ENSDART00000141912
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
chr10_-_10863936 1.86 ENSDART00000180568
NOTCH regulated ankyrin repeat protein a
chr10_-_10864331 1.83 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr4_-_74367912 1.82 ENSDART00000174199
ENSDART00000165257
protein tyrosine phosphatase, receptor type, b
chr14_+_4151379 1.80 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr20_+_36234335 1.77 ENSDART00000193484
ENSDART00000181664
cornichon family AMPA receptor auxiliary protein 3
chr10_+_9195190 1.71 ENSDART00000136364
anthrax toxin receptor 2b
chr6_-_14292307 1.68 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr7_+_38445938 1.55 ENSDART00000173467
centrosomal protein 89
chr16_+_26449615 1.51 ENSDART00000039746
erythrocyte membrane protein band 4.1b
chr7_-_15185811 1.51 ENSDART00000031049
si:dkey-172h23.2
chr24_-_37877978 1.43 ENSDART00000128574
transmembrane protein 204
chr11_+_13159988 1.42 ENSDART00000064176
MOB kinase activator 3C
chr10_-_42297889 1.37 ENSDART00000099262
transcription factor 7 like 1a
chr23_-_31372639 1.35 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
high mobility group nucleosomal binding domain 3
chr15_+_19783352 1.34 ENSDART00000178784
ENSDART00000092560
zona pellucida-like domain containing 1b
chr16_-_17300030 1.34 ENSDART00000149267
Kell blood group, metallo-endopeptidase
chr18_+_22220656 1.30 ENSDART00000191862
RHO family interacting cell polarization regulator 1
chr3_+_27722355 1.26 ENSDART00000132761
Rho GDP dissociation inhibitor (GDI) gamma
chr16_+_36671064 1.25 ENSDART00000109703
collagen, type VI, alpha 4a
chr17_+_30546579 1.24 ENSDART00000154385
NHS-like 1a
chr13_+_33655404 1.18 ENSDART00000023379
mitochondrial genome maintenance exonuclease 1
chr13_-_36579086 1.16 ENSDART00000146671
lectin, galactoside binding soluble 3a
chr17_+_24851951 1.14 ENSDART00000180746
connexin 35.4
chr8_-_18613948 1.13 ENSDART00000089172
coproporphyrinogen oxidase
chr22_+_12431608 1.12 ENSDART00000108609
Rho family GTPase 3a
chr19_+_48018464 1.10 ENSDART00000172307
ENSDART00000163848
si:ch1073-205c8.3
chr1_-_51720633 1.08 ENSDART00000045894
ribonuclease H2, subunit A
chr8_-_29706882 1.08 ENSDART00000045909
perforin 1.5
chr8_+_48491387 1.07 ENSDART00000086053
si:ch211-263k4.2
chr5_-_56513825 1.07 ENSDART00000024207
T-box 2a
chr14_-_33083539 1.07 ENSDART00000160173
discs, large homolog 3 (Drosophila)
chr22_-_30881738 1.06 ENSDART00000059965
si:dkey-49n23.1
chr13_-_25305179 1.04 ENSDART00000110064
plasminogen activator, urokinase a
chr14_+_23076207 1.04 ENSDART00000161628
ecto-NOX disulfide-thiol exchanger 2
chr13_-_24874950 1.03 ENSDART00000077775
K(lysine) acetyltransferase 6B
chr19_+_48018802 1.01 ENSDART00000161339
ENSDART00000166978
si:ch1073-205c8.3
chr16_+_46492994 1.01 ENSDART00000134734
rapunzel 5
chr5_+_46424437 1.01 ENSDART00000186511
versican a
chr23_-_8733092 1.00 ENSDART00000014222
transcription elongation factor A (SII), 2
chr15_-_41714329 0.99 ENSDART00000154113

chr21_-_5799122 0.98 ENSDART00000129351
ENSDART00000151202
cyclin I
chr24_-_37877554 0.98 ENSDART00000132219
transmembrane protein 204
chr3_-_34547000 0.98 ENSDART00000166623
septin 9a
chr9_-_23807032 0.96 ENSDART00000027443
extended synaptotagmin-like protein 3
chr13_-_33654931 0.95 ENSDART00000020350
sorting nexin 5
chr13_-_36798204 0.91 ENSDART00000012357
salvador family WW domain containing protein 1
chr13_-_33009734 0.91 ENSDART00000134140
RNA binding motif protein 25a
chr2_+_2110271 0.87 ENSDART00000148460
desmoplakin a
chr15_+_20530649 0.86 ENSDART00000186312
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr14_+_38786298 0.86 ENSDART00000164440
si:ch211-195b11.3
chr3_-_54992934 0.86 ENSDART00000053095
ENSDART00000145766
rhomboid 5 homolog 1a (Drosophila)
chr24_-_20658446 0.85 ENSDART00000127923
natural killer cell triggering receptor
chr4_+_4849789 0.84 ENSDART00000130818
ENSDART00000127751
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr5_+_9428876 0.84 ENSDART00000081791
UDP glucuronosyltransferase 2 family, polypeptide A7
chr9_-_3671911 0.84 ENSDART00000102900
Sp5 transcription factor a
chr12_-_19862912 0.82 ENSDART00000145788
shisa family member 9a
chr19_-_7540821 0.78 ENSDART00000143958
limb and CNS expressed 1 like
chr17_+_49081828 0.77 ENSDART00000156492
T cell lymphoma invasion and metastasis 2a
chr5_-_36597612 0.76 ENSDART00000031270
ENSDART00000122098
ras homolog gene family, member Gc
chr14_+_8475007 0.75 ENSDART00000148210
DnaJ (Hsp40) homolog, subfamily C, member 4
chr24_-_24796583 0.75 ENSDART00000144791
ENSDART00000146570
phosphodiesterase 7A
chr5_-_66028714 0.75 ENSDART00000022625
ENSDART00000164228
NOTCH regulated ankyrin repeat protein b
chr24_+_28953089 0.74 ENSDART00000153761
RNA-binding region (RNP1, RRM) containing 3
chr15_-_47468085 0.71 ENSDART00000164438
inositol polyphosphate phosphatase-like 1a
chr19_-_32641725 0.70 ENSDART00000165006
ENSDART00000188185
hippocalcin
chr8_-_11067079 0.68 ENSDART00000181986
DENN/MADD domain containing 2C
chr9_+_41218967 0.67 ENSDART00000000280
ENSDART00000145674
signal transducer and activator of transcription 1b
chr19_-_12648408 0.64 ENSDART00000103692
family with sequence similarity 210, member Aa
chr3_+_21669545 0.63 ENSDART00000156527
corticotropin releasing hormone receptor 1
chr5_+_15202495 0.63 ENSDART00000144915
T-box 1
chr10_-_4375190 0.61 ENSDART00000016102

chr12_+_35587971 0.61 ENSDART00000166072
ENSDART00000181861
ENSDART00000158043
charged multivesicular body protein 6b
chr18_+_26829362 0.61 ENSDART00000132728
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr13_-_27916439 0.60 ENSDART00000139081
ENSDART00000087097
opioid growth factor receptor-like 1
chr13_-_31389661 0.60 ENSDART00000134630
zinc finger, DHHC-type containing 16a
chr12_+_35067863 0.58 ENSDART00000152849
synaptotagmin XV
chr22_-_11729350 0.57 ENSDART00000105813
keratin 222
chr18_+_26829086 0.57 ENSDART00000098356
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr9_+_19623363 0.57 ENSDART00000142471
ENSDART00000147662
ENSDART00000136053
pyridoxal (pyridoxine, vitamin B6) kinase a
chr25_+_10793478 0.56 ENSDART00000058339
ENSDART00000134923
adaptor-related protein complex 3, sigma 2 subunit
chr13_-_3516473 0.54 ENSDART00000146240
parkin RBR E3 ubiquitin protein ligase
chr19_+_3842891 0.54 ENSDART00000159043
LSM10, U7 small nuclear RNA associated
chr11_-_29563437 0.53 ENSDART00000163958
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr20_+_45620076 0.52 ENSDART00000113806
heterogeneous nuclear ribonucleoprotein A0, like
chr24_-_26310854 0.52 ENSDART00000080113
apolipoprotein Db
chr11_-_27962757 0.51 ENSDART00000147386
endothelin converting enzyme 1
chr18_-_16953978 0.51 ENSDART00000100126
A kinase (PRKA) interacting protein 1
chr21_-_4849029 0.51 ENSDART00000168930
ENSDART00000151019
notch 1a
chr5_+_9348284 0.51 ENSDART00000149417
T-cell acute lymphocytic leukemia 2
chr19_-_11015238 0.51 ENSDART00000010997
tropomyosin 3
chr8_+_23009662 0.49 ENSDART00000030885
uridine-cytidine kinase 1-like 1a
chr3_+_46315016 0.49 ENSDART00000157199
MKL/myocardin-like 2b
chr9_-_22355391 0.48 ENSDART00000009115
crystallin, gamma M3
chr24_-_19718077 0.47 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr20_-_32045057 0.46 ENSDART00000152970
ENSDART00000034248
RAB32a, member RAS oncogene family
chr11_+_34921492 0.46 ENSDART00000128070
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr18_-_5103931 0.45 ENSDART00000188091
programmed cell death 10a
chr7_-_71837213 0.45 ENSDART00000168645
ENSDART00000160512
calcium channel, voltage-dependent, beta 2a
chr21_-_38852860 0.45 ENSDART00000166101
toll-like receptor 22
chr21_+_34976600 0.43 ENSDART00000191672
ENSDART00000139635
RNA binding motif protein 11
chr5_-_57361594 0.43 ENSDART00000112793
cell division cycle 26 homolog
chr3_+_49021079 0.40 ENSDART00000162012
zgc:163083
chr16_-_13881139 0.39 ENSDART00000138904
ENSDART00000090221
ENSDART00000135099
CDC42 effector protein (Rho GTPase binding) 5
chr12_+_38563073 0.39 ENSDART00000009172
tweety family member 2
chr3_-_29869120 0.38 ENSDART00000138327
ribosomal protein L3
chr25_+_35304903 0.38 ENSDART00000034313
ENSDART00000187659
growth arrest-specific 2a
chr23_-_36003282 0.38 ENSDART00000103150
calcium binding and coiled-coil domain 1a
chr2_+_3696038 0.37 ENSDART00000150499
ENSDART00000136906
ENSDART00000164152
ENSDART00000128514
ENSDART00000108964
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr5_-_23675222 0.37 ENSDART00000135153
si:dkey-110k5.6
chr21_-_43485351 0.36 ENSDART00000151597
ankyrin repeat domain 46a
chr20_-_54508650 0.36 ENSDART00000147642

chr23_-_36003441 0.36 ENSDART00000164699
calcium binding and coiled-coil domain 1a
chr5_-_66028371 0.36 ENSDART00000183012
NOTCH regulated ankyrin repeat protein b
chr8_+_21159122 0.35 ENSDART00000033491
SPRY domain containing 4
chr18_-_6943577 0.33 ENSDART00000132399
si:dkey-266m15.6
chr9_-_7089303 0.32 ENSDART00000146609
cytochrome C oxidase assembly factor 5
chr20_-_26536581 0.31 ENSDART00000181810
syntaxin 11b, tandem duplicate 2
chr5_+_44944778 0.30 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
doublesex and mab-3 related transcription factor 1
chr21_+_20549395 0.29 ENSDART00000181633
ephrin-A5a
chr2_+_55916911 0.29 ENSDART00000189483
ENSDART00000183647
ENSDART00000083470
ataxia, cerebellar, Cayman type b
chr8_-_41273461 0.28 ENSDART00000190598
ring finger protein 10
chr2_+_31957554 0.26 ENSDART00000012413
ANKH inorganic pyrophosphate transport regulator b
chr16_-_21047872 0.26 ENSDART00000131582
chromobox homolog 3b
chr8_-_41273768 0.26 ENSDART00000108518
ring finger protein 10
chr2_-_32769759 0.25 ENSDART00000178951
beaded filament structural protein 2, phakinin
chr7_-_1918971 0.25 ENSDART00000181759

chr18_-_11184584 0.24 ENSDART00000040500
tetraspanin 9a
chr18_-_37241080 0.24 ENSDART00000126421
ENSDART00000078064
SIX homeobox 9
chr5_+_25736979 0.23 ENSDART00000175959
abhydrolase domain containing 17B
chr7_+_19424857 0.23 ENSDART00000173674
si:ch211-212k18.6
chr6_-_49861506 0.23 ENSDART00000121809
GNAS complex locus
chr15_-_31147301 0.23 ENSDART00000157145
ENSDART00000155473
ENSDART00000048103
kinase suppressor of ras 1b
chr17_+_35362851 0.23 ENSDART00000137659
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr21_-_40562705 0.22 ENSDART00000158289
ENSDART00000171997
TAO kinase 1b
chr10_+_40624702 0.22 ENSDART00000109129
zgc:172131
chr19_-_12648122 0.21 ENSDART00000151184
family with sequence similarity 210, member Aa
chr23_-_21471022 0.21 ENSDART00000104206
hairy-related 4, tandem duplicate 2
chr7_+_36041509 0.20 ENSDART00000162850
iroquois homeobox 3a
chr8_+_14915332 0.20 ENSDART00000164385
c-abl oncogene 2, non-receptor tyrosine kinase
chr17_-_15777350 0.18 ENSDART00000155711
ankyrin repeat domain 6a
chr15_+_5339056 0.18 ENSDART00000174319

chr23_-_31346319 0.17 ENSDART00000008401
ENSDART00000138106
pleckstrin homology domain interacting protein
chr6_-_25384792 0.17 ENSDART00000169030
zgc:153916
chr9_-_14084044 0.16 ENSDART00000141571
fer-1-like family member 6
chr2_+_1881334 0.16 ENSDART00000161420
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr24_+_31374324 0.16 ENSDART00000172335
ENSDART00000163162
copine III
chr3_+_31058464 0.16 ENSDART00000153381
si:dkey-66i24.7
chr18_-_21177674 0.15 ENSDART00000060175
si:dkey-12e7.4
chr3_+_37574885 0.15 ENSDART00000055225
wingless-type MMTV integration site family, member 9B
chr22_+_22302614 0.15 ENSDART00000049434
secretory carrier membrane protein 4
chr19_+_24896409 0.15 ENSDART00000049840
EYA transcriptional coactivator and phosphatase 3
chr1_+_1941031 0.15 ENSDART00000110331
si:ch211-132g1.7
chr6_+_72040 0.14 ENSDART00000122957
crystallin, gamma M4
chr20_+_5065268 0.13 ENSDART00000053883
si:dkey-60a16.1
chr8_+_48848200 0.13 ENSDART00000130673
tumor protein p73
chr23_-_21446985 0.13 ENSDART00000044080
hairy-related 12
chr3_-_41995321 0.12 ENSDART00000192277
tweety family member 3a
chr12_-_6905375 0.12 ENSDART00000152322
protocadherin-related 15b
chr4_+_62598975 0.12 ENSDART00000163548
si:ch211-79g12.2
chr2_+_8112449 0.12 ENSDART00000138136
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a
chr6_-_12172424 0.12 ENSDART00000109344
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr21_+_43485512 0.11 ENSDART00000026666
autophagy related 4A, cysteine peptidase
chr5_-_33287691 0.11 ENSDART00000004238
ribosomal protein L7a
chr2_+_35728033 0.11 ENSDART00000002094
ankyrin repeat domain 45

Network of associatons between targets according to the STRING database.

First level regulatory network of rbpjb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.7 GO:0003210 cardiac atrium formation(GO:0003210)
1.6 4.9 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.8 3.3 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.8 2.5 GO:0003218 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.7 3.5 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.6 1.9 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.6 3.7 GO:0055016 hypochord development(GO:0055016)
0.5 1.4 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.4 5.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.4 1.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.4 1.1 GO:0072025 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.3 1.4 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.3 1.0 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.3 3.0 GO:0021794 thalamus development(GO:0021794)
0.3 7.9 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.2 1.2 GO:0090280 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677) positive regulation of calcium ion import(GO:0090280)
0.2 0.6 GO:0003156 regulation of organ formation(GO:0003156)
0.2 3.1 GO:0042026 protein refolding(GO:0042026)
0.2 1.0 GO:0007624 ultradian rhythm(GO:0007624)
0.2 0.6 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.2 1.7 GO:1901998 toxin transport(GO:1901998)
0.2 1.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 3.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 2.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.5 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 2.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.7 GO:0090024 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 4.3 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 1.0 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.6 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.3 GO:0030238 male sex determination(GO:0030238)
0.1 1.8 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.9 GO:1904950 negative regulation of protein transport(GO:0051224) negative regulation of establishment of protein localization(GO:1904950)
0.1 3.6 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.1 1.2 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 0.2 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 1.1 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.5 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.5 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 1.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.5 GO:0044211 CTP salvage(GO:0044211)
0.1 2.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.7 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.5 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 3.4 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.4 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 5.1 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 1.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.9 GO:0043588 skin development(GO:0043588)
0.0 3.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.7 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.5 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 3.1 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.2 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.4 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 2.3 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.5 GO:0007568 aging(GO:0007568)
0.0 1.0 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.9 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.5 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 3.4 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.8 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.4 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.7 GO:0006414 translational elongation(GO:0006414)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 14.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 7.9 GO:0031430 M band(GO:0031430)
0.3 1.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 0.5 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 1.2 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.1 3.6 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.9 GO:0014704 intercalated disc(GO:0014704)
0.1 1.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 2.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 2.8 GO:0031941 filamentous actin(GO:0031941)
0.1 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 4.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.6 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 7.9 GO:0009986 cell surface(GO:0009986)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 3.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.9 GO:0005884 actin filament(GO:0005884)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0030175 filopodium(GO:0030175)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.2 GO:0008266 poly(U) RNA binding(GO:0008266)
1.1 11.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.8 3.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.7 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 1.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.2 4.3 GO:0015026 coreceptor activity(GO:0015026)
0.2 3.1 GO:0016408 C-acyltransferase activity(GO:0016408)
0.2 3.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 0.7 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 1.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 1.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 2.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.9 GO:0034452 dynactin binding(GO:0034452)
0.1 3.6 GO:0005518 collagen binding(GO:0005518)
0.1 1.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 7.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 2.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 2.0 GO:0019003 GDP binding(GO:0019003)
0.1 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 3.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0051430 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 5.1 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 3.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 4.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 11.3 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 2.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.2 GO:0060090 binding, bridging(GO:0060090)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 6.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 4.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation