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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for rfx7a+rfx7b

Z-value: 1.00

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Transcription factors associated with rfx7a+rfx7b

Gene Symbol Gene ID Gene Info
ENSDARG00000077237 regulatory factor X7a
ENSDARG00000103691 regulatory factor X7b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rfx7adr11_v1_chr7_+_34506937_345069370.471.4e-06Click!
rfx7bdr11_v1_chr25_+_388258_3882580.278.2e-03Click!

Activity profile of rfx7a+rfx7b motif

Sorted Z-values of rfx7a+rfx7b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_47193564 16.24 ENSDART00000172453
limbic system-associated membrane protein
chr19_+_21266008 9.70 ENSDART00000024639
teashirt zinc finger homeobox 1
chr15_+_22267847 9.40 ENSDART00000110665
sperm autoantigenic protein 17
chr1_+_8662530 8.78 ENSDART00000054989
fascin actin-bundling protein 1b
chr19_+_2279051 8.64 ENSDART00000182103
integrin, beta 8
chr25_+_34407740 8.53 ENSDART00000012677
si:dkey-37f18.2
chr19_+_2275019 8.51 ENSDART00000136138
integrin, beta 8
chr6_+_12853655 8.31 ENSDART00000156341
family with sequence similarity 117, member Ba
chr6_-_33023745 7.74 ENSDART00000156211
adenylate cyclase activating polypeptide 1b (pituitary) receptor type I
chr20_-_29475172 7.19 ENSDART00000183164
secretogranin V
chr20_-_29474859 7.10 ENSDART00000152906
ENSDART00000045249
secretogranin V
chr1_+_604127 7.09 ENSDART00000133165
junctional adhesion molecule 2a
chr22_+_3223489 7.06 ENSDART00000082011
lens intrinsic membrane protein 2.2
chr14_+_6954579 6.84 ENSDART00000060998
NME/NM23 family member 5
chr19_-_47526737 6.82 ENSDART00000186636
secretogranin V
chr24_-_37472727 6.71 ENSDART00000134152
clusterin associated protein 1
chr18_+_28102620 6.71 ENSDART00000132342
KIAA1549-like b
chr17_+_23937262 6.65 ENSDART00000113276
si:ch211-189k9.2
chr23_+_6272638 6.63 ENSDART00000190366
synaptotagmin IIa
chr15_+_16897554 6.38 ENSDART00000154679
yippee-like 2b
chr15_+_29085955 5.99 ENSDART00000156799
si:ch211-137a8.4
chr19_+_27479563 5.64 ENSDART00000049368
ENSDART00000185426
alpha tubulin acetyltransferase 1
chr17_-_33716688 5.63 ENSDART00000043651
dynein, axonemal, light chain 1
chr21_+_22124736 5.43 ENSDART00000130179
ENSDART00000172573
cullin 5b
chr19_-_47527093 5.41 ENSDART00000171379
ENSDART00000171140
ENSDART00000114886
secretogranin V
chr13_+_33117528 5.09 ENSDART00000085719
si:ch211-10a23.2
chr2_-_58795694 4.96 ENSDART00000176425
protein tyrosine phosphatase, receptor type, s, a
chr10_+_37145007 4.95 ENSDART00000131777
CUE domain containing 1a
chr23_+_45538932 4.71 ENSDART00000135602
si:ch73-290k24.6
chr13_-_29406534 4.60 ENSDART00000100877
zgc:153142
chr3_-_5664123 4.52 ENSDART00000145866
si:ch211-106h11.1
chr18_+_2168695 4.45 ENSDART00000165855
dynein axonemal assembly factor 4
chr22_-_25033105 4.44 ENSDART00000124220
neuronal pentraxin receptor b
chr17_-_18888959 4.40 ENSDART00000080029
adenylate kinase 7b
chr24_+_22021675 4.26 ENSDART00000081234
rhophilin associated tail protein 1-like
chr11_-_30352333 4.26 ENSDART00000030794
transmembrane protein 169a
chr17_+_33296436 4.13 ENSDART00000123114
DnaJ (Hsp40) homolog, subfamily C, member 27
chr1_-_45633955 4.05 ENSDART00000044057
septin 3
chr5_-_57920600 4.05 ENSDART00000132376
si:dkey-27p23.3
chr10_-_17231917 4.03 ENSDART00000038577
RAB36, member RAS oncogene family
chr6_+_33537267 4.01 ENSDART00000040334
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr18_+_29950233 4.00 ENSDART00000146431
ATM interactor
chr22_+_25049563 3.93 ENSDART00000078173
double zinc ribbon and ankyrin repeat domains 1
chr19_+_27479838 3.93 ENSDART00000103922
alpha tubulin acetyltransferase 1
chr12_+_13404784 3.93 ENSDART00000167977
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr20_-_12642685 3.81 ENSDART00000173257
si:dkey-97l20.6
chr25_+_5755314 3.70 ENSDART00000172088
ENSDART00000164208
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr10_-_17232372 3.65 ENSDART00000135679
RAB36, member RAS oncogene family
chr22_+_438714 3.61 ENSDART00000136491
cadherin, EGF LAG seven-pass G-type receptor 2
chr17_-_22067451 3.59 ENSDART00000156872
tau tubulin kinase 1b
chr21_+_21791343 3.56 ENSDART00000151654
sialidase 3 (membrane sialidase), tandem duplicate 1
chr19_+_43123331 3.54 ENSDART00000187836

chr20_-_4766645 3.51 ENSDART00000147071
ENSDART00000152398
adenylate kinase 7a
chr21_-_12036134 3.48 ENSDART00000031658
tubulin polyglutamylase complex subunit 2
chr18_+_5618368 3.43 ENSDART00000159945
unc-51 like kinase 3
chr25_+_21180695 3.42 ENSDART00000012923
ELKS/RAB6-interacting/CAST family member 1a
chr6_+_515181 3.40 ENSDART00000171374
si:ch73-379f7.5
chr12_+_7445595 3.28 ENSDART00000103536
ENSDART00000152524
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr5_-_21044693 3.27 ENSDART00000140298
si:dkey-13n15.2
chr2_+_59527149 3.26 ENSDART00000168568

chr11_+_37137196 3.25 ENSDART00000172950
WNK lysine deficient protein kinase 2
chr17_-_24684687 3.24 ENSDART00000105457
MORN repeat containing 2
chr6_-_18250857 3.18 ENSDART00000159486
APC11 anaphase promoting complex subunit 11 homolog (yeast)
chr3_+_28831622 3.17 ENSDART00000184130
ENSDART00000191294
fleer
chr6_+_18251140 3.15 ENSDART00000169752
coiled-coil domain containing 40
chr3_+_28831450 3.14 ENSDART00000055422
fleer
chr9_+_2452672 3.12 ENSDART00000193993
chimerin 1
chr20_+_591505 3.08 ENSDART00000046438
potassium channel, subfamily K, member 2b
chr17_-_8173380 3.05 ENSDART00000148520
spectrin repeat containing, nuclear envelope 1b
chr24_+_38155830 3.01 ENSDART00000152019
si:ch211-234p6.5
chr17_+_33296852 2.98 ENSDART00000154580
DnaJ (Hsp40) homolog, subfamily C, member 27
chr20_+_33519435 2.95 ENSDART00000061829
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr6_+_52350443 2.88 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr17_+_11500628 2.87 ENSDART00000155660
EF-hand calcium binding domain 2
chr10_+_15255198 2.82 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr20_+_52554352 2.81 ENSDART00000153217
ENSDART00000145230
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr10_+_15255012 2.81 ENSDART00000023766
very low density lipoprotein receptor
chr7_+_38395197 2.77 ENSDART00000138669
centrosomal protein 89
chr1_-_21538329 2.75 ENSDART00000182798
ENSDART00000193518
ENSDART00000183873
ENSDART00000183376
WD repeat domain 19
chr14_-_52542928 2.68 ENSDART00000075749
protein phosphatase 2, regulatory subunit B, beta a
chr2_-_1569250 2.67 ENSDART00000167202
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr1_-_21538673 2.67 ENSDART00000131257
WD repeat domain 19
chr2_+_33796207 2.67 ENSDART00000124647
KISS1 receptor a
chr2_-_54039293 2.57 ENSDART00000166013
abhydrolase domain containing 8a
chr12_+_17620067 2.55 ENSDART00000073599
radial spoke head 10 homolog B
chr6_-_19683406 2.54 ENSDART00000158041
cilia and flagella associated protein 52
chr17_+_27545183 2.54 ENSDART00000129392
PARK2 co-regulated
chr7_-_40738774 2.51 ENSDART00000084179
ring finger protein 32
chr19_+_8985230 2.50 ENSDART00000018973
secretory carrier membrane protein 3
chr24_+_22022109 2.49 ENSDART00000133686
rhophilin associated tail protein 1-like
chr15_+_34062460 2.44 ENSDART00000164654
si:dkey-30e9.6
chr19_+_22062202 2.42 ENSDART00000100181
spalt-like transcription factor 3b
chr24_-_6647275 2.41 ENSDART00000161494
Rho GTPase activating protein 21a
chr7_-_72423666 2.41 ENSDART00000191214
rabphilin 3A homolog (mouse), b
chr19_-_10648523 2.36 ENSDART00000059358
tektin 2 (testicular)
chr11_+_43401201 2.32 ENSDART00000190128
vasoactive intestinal peptide b
chr13_-_36703164 2.32 ENSDART00000044357
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr17_-_2721336 2.29 ENSDART00000109582
ENSDART00000192691
ENSDART00000189381
spermatogenesis associated 7
chr19_+_19976990 2.26 ENSDART00000052627
neuropeptide VF precursor
chr19_+_9091673 2.25 ENSDART00000052898
si:ch211-81a5.5
chr14_-_38827442 2.24 ENSDART00000160000
spindle apparatus coiled-coil protein 1
chr25_-_16755340 2.23 ENSDART00000124729
ENSDART00000110859
RIB43A domain with coiled-coils 2
chr9_-_23156908 2.22 ENSDART00000135461
LY6/PLAUR domain containing 6B
chr4_-_1497384 2.17 ENSDART00000093236
zmp:0000000711
chr17_+_21818093 2.16 ENSDART00000125335
IKAROS family zinc finger 5
chr9_+_27339505 2.15 ENSDART00000011822
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr9_+_52411530 2.14 ENSDART00000163684
NME/NM23 family member 8
chr20_-_32007209 2.13 ENSDART00000021575
androglobin
chr11_-_12417952 2.13 ENSDART00000135694
si:dkey-27d5.9
chr13_+_31205439 2.12 ENSDART00000132326
protein tyrosine phosphatase, non-receptor type 20
chr4_+_77919987 2.12 ENSDART00000150171
tubulin tyrosine ligase-like family, member 1
chr21_-_45349548 2.12 ENSDART00000008454
S-phase kinase-associated protein 1
chr11_+_28476298 2.09 ENSDART00000122319
leucine rich repeat containing 38b
chr17_+_31592191 2.09 ENSDART00000153765
si:dkey-13p1.3
chr14_+_24283915 2.08 ENSDART00000172868
kelch-like family member 3
chr12_+_2381213 2.07 ENSDART00000188007

chr3_+_17456428 2.05 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
chr3_-_12026741 2.05 ENSDART00000132238
cilia and flagella associated protein 70
chr16_-_24561354 2.05 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
chr25_-_13659249 2.04 ENSDART00000045488
casein kinase 2, alpha prime polypeptide b
chr14_-_38826739 2.03 ENSDART00000187633
spindle apparatus coiled-coil protein 1
chr15_+_31735931 1.98 ENSDART00000185681
ENSDART00000149137
relaxin/insulin-like family peptide receptor 2b
chr20_+_13969414 1.97 ENSDART00000049864
retinal degeneration 3
chr3_+_24458899 1.96 ENSDART00000156655
chromobox homolog 6b
chr1_-_17675037 1.96 ENSDART00000142689
si:dkey-256e7.5
chr12_+_46582168 1.96 ENSDART00000189402
Usher syndrome 1Gb (autosomal recessive)
chr11_-_12512122 1.94 ENSDART00000145338
si:dkey-27d5.3
chr18_-_44359726 1.92 ENSDART00000166935
PR domain containing 10
chr11_-_28911172 1.90 ENSDART00000168493
immunoglobin superfamily, member 21a
chr19_+_27589201 1.90 ENSDART00000182060
si:dkeyp-46h3.1
chr2_+_55914699 1.89 ENSDART00000157905
ataxia, cerebellar, Cayman type b
chr21_+_26726936 1.86 ENSDART00000065392
calmodulin 2a (phosphorylase kinase, delta)
chr2_+_30786773 1.85 ENSDART00000019029
ENSDART00000145681
ATPase H+ transporting V1 subunit H
chr4_+_9609905 1.82 ENSDART00000142284
ENSDART00000150687
meiosis/spermiogenesis associated 1
chr5_-_43071058 1.80 ENSDART00000165546
si:dkey-245n4.2
chr4_+_34343524 1.79 ENSDART00000171694
si:ch211-246b8.5
chr8_+_16990120 1.79 ENSDART00000018934
phosphodiesterase 4D, cAMP-specific
chr11_-_12379541 1.79 ENSDART00000171717
zgc:174353
chr11_-_12364122 1.78 ENSDART00000170129
zgc:174353
chr6_-_16406210 1.78 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr20_-_44576949 1.76 ENSDART00000148639
UBX domain protein 2A
chr17_+_33767890 1.75 ENSDART00000193177
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr14_-_30724165 1.74 ENSDART00000020936
fibroblast growth factor (acidic) intracellular binding protein a
chr2_+_45362016 1.71 ENSDART00000139154
calmodulin regulated spectrin-associated protein family, member 2b
chr13_-_6218248 1.69 ENSDART00000159052
si:zfos-1056e6.1
chr8_+_31016180 1.69 ENSDART00000130870
ENSDART00000143604
outer dense fiber of sperm tails 2b
chr13_-_48764180 1.68 ENSDART00000167157
si:ch1073-266p11.2
chr23_+_12134839 1.67 ENSDART00000128551
ENSDART00000141204
tubulin tyrosine ligase-like family, member 9
chr24_+_25467465 1.66 ENSDART00000189933
small muscle protein, X-linked
chr17_+_21817859 1.65 ENSDART00000143832
ENSDART00000141462
IKAROS family zinc finger 5
chr1_+_38818268 1.64 ENSDART00000166864
signal peptidase complex subunit 3
chr8_-_14080534 1.64 ENSDART00000042867
death effector domain containing
chr14_+_30413312 1.62 ENSDART00000186864
CCR4-NOT transcription complex, subunit 7
chr21_-_45348983 1.61 ENSDART00000188017
S-phase kinase-associated protein 1
chr23_-_45539306 1.60 ENSDART00000161913

chr23_+_7710447 1.60 ENSDART00000168199
kinesin family member 3B
chr11_-_12232769 1.59 ENSDART00000180116
si:ch211-156l18.4
chr11_-_12232929 1.55 ENSDART00000127611
si:ch211-156l18.4
chr11_+_11374021 1.51 ENSDART00000170806
si:dkey-23f9.8
chr14_+_23874062 1.49 ENSDART00000172149
SH3 domain containing ring finger 2
chr13_+_24842857 1.48 ENSDART00000123866
dual specificity phosphatase 13a
chr7_-_41881177 1.47 ENSDART00000174258
ENSDART00000018972
zgc:92818
chr5_+_32260502 1.47 ENSDART00000149020
si:ch211-158m24.12
chr14_+_24840669 1.47 ENSDART00000106039
Rho guanine nucleotide exchange factor (GEF) 37
chr9_-_22963897 1.46 ENSDART00000133676
si:dkey-91i10.2
chr5_+_24882633 1.46 ENSDART00000111302
rhomboid domain containing 3
chr6_+_6802142 1.45 ENSDART00000065566
D-tyrosyl-tRNA deacylase 1
chr18_+_27101096 1.45 ENSDART00000171128
ENSDART00000086094
pleckstrin homology domain containing, family A member 7a
chr3_+_60716904 1.45 ENSDART00000168280
forkhead box J1a
chr4_-_4261673 1.44 ENSDART00000150694
CD9 molecule b
chr11_+_1533097 1.43 ENSDART00000066191
intraflagellar transport 52 homolog (Chlamydomonas)
chr13_+_24717880 1.41 ENSDART00000147713
cilia and flagella associated protein 43
chr24_-_36910224 1.41 ENSDART00000079233
dynein, axonemal, assembly factor 3 like
chr13_-_4303641 1.40 ENSDART00000136262
protein phosphatase 2, regulatory subunit B', delta
chr5_-_52813442 1.38 ENSDART00000169305
zgc:158260
chr12_+_28955766 1.38 ENSDART00000123417
ENSDART00000139347
zinc finger protein 668
chr24_+_26345427 1.34 ENSDART00000089756
leucine rich repeat containing 34
chr9_+_48415043 1.33 ENSDART00000159930
low density lipoprotein receptor-related protein 2a
chr15_-_1534232 1.30 ENSDART00000056763
ENSDART00000133943
intraflagellar transport 80 homolog (Chlamydomonas)
chr16_-_50203058 1.29 ENSDART00000154570
V-set and immunoglobulin domain containing 10 like
chr16_-_28709874 1.29 ENSDART00000127753
ADAM metallopeptidase domain 15
chr11_-_34720629 1.29 ENSDART00000162066
ENSDART00000161471
dynein, axonemal, heavy chain 1
chr4_-_73520581 1.27 ENSDART00000171513
si:ch73-266f23.1
chr5_-_26566435 1.27 ENSDART00000146070
ARVCF, delta catenin family member b
chr22_-_11438627 1.26 ENSDART00000007649
MID1 interacting protein 1b
chr6_+_6802582 1.20 ENSDART00000189422
D-tyrosyl-tRNA deacylase 1
chr18_+_50890749 1.19 ENSDART00000174109
si:ch1073-450f2.1
chr13_+_24679674 1.18 ENSDART00000033090
ENSDART00000139854
zgc:66426
chr2_+_30787128 1.18 ENSDART00000189233
ATPase H+ transporting V1 subunit H
chr11_-_12717004 1.17 ENSDART00000122020
si:ch211-209f22.3
chr13_-_8279533 1.16 ENSDART00000109666
si:ch211-250c4.5
chr24_+_26345609 1.15 ENSDART00000186844
leucine rich repeat containing 34
chr13_+_159504 1.13 ENSDART00000057248
EWS RNA-binding protein 1b
chr9_+_48219111 1.13 ENSDART00000111225
ENSDART00000145972
coiled-coil domain containing 173
chr4_-_73727926 1.13 ENSDART00000171414
si:dkey-262g12.14
chr11_-_12437234 1.12 ENSDART00000169324
zgc:174355
chr20_-_28642061 1.11 ENSDART00000135513
regulator of G protein signaling 6
chr7_+_7630409 1.08 ENSDART00000172934
chloride channel 3
chr19_+_5480327 1.06 ENSDART00000148794
junction plakoglobin b
chr1_-_6225285 1.05 ENSDART00000141653
malate dehydrogenase 1B, NAD (soluble)

Network of associatons between targets according to the STRING database.

First level regulatory network of rfx7a+rfx7b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
1.5 4.5 GO:0036159 inner dynein arm assembly(GO:0036159)
0.8 6.8 GO:0048240 sperm capacitation(GO:0048240)
0.8 6.7 GO:0036372 opsin transport(GO:0036372)
0.8 3.1 GO:0021557 oculomotor nerve development(GO:0021557)
0.8 2.3 GO:0060986 regulation of endocrine process(GO:0044060) endocrine hormone secretion(GO:0060986)
0.7 2.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.7 28.8 GO:0046883 regulation of hormone secretion(GO:0046883)
0.6 3.8 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.6 4.4 GO:0003352 regulation of cilium movement(GO:0003352)
0.5 17.2 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.5 5.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.5 1.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 4.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.5 5.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.5 7.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.4 3.0 GO:0048069 eye pigmentation(GO:0048069)
0.4 4.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.4 5.0 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.3 6.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 2.7 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3 1.3 GO:0070293 renal absorption(GO:0070293)
0.3 3.4 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.3 4.0 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.3 9.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.3 3.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.3 2.4 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.3 2.3 GO:0043584 nose development(GO:0043584)
0.3 3.6 GO:0021754 facial nucleus development(GO:0021754)
0.3 7.1 GO:0007520 myoblast fusion(GO:0007520)
0.3 3.2 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.3 1.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.2 1.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 2.0 GO:0050957 equilibrioception(GO:0050957)
0.2 3.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 1.1 GO:0002159 desmosome assembly(GO:0002159)
0.2 1.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 3.2 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 11.3 GO:0003341 cilium movement(GO:0003341)
0.2 1.6 GO:0006465 signal peptide processing(GO:0006465)
0.2 1.9 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 3.5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 2.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 7.7 GO:0021854 hypothalamus development(GO:0021854)
0.2 3.7 GO:0007020 microtubule nucleation(GO:0007020)
0.2 1.7 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.2 2.0 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 1.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.7 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 1.7 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 3.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 3.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.8 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 8.3 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.1 1.8 GO:0036065 fucosylation(GO:0036065)
0.1 0.9 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 8.8 GO:0051017 actin filament bundle assembly(GO:0051017)
0.1 1.8 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.7 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 10.1 GO:0006475 internal protein amino acid acetylation(GO:0006475) internal peptidyl-lysine acetylation(GO:0018393)
0.1 6.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 4.4 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.4 GO:0042073 intraciliary transport(GO:0042073)
0.1 1.4 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 2.2 GO:0061512 protein localization to cilium(GO:0061512)
0.1 0.7 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 1.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.4 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 2.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 4.1 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 2.8 GO:0006414 translational elongation(GO:0006414)
0.0 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 19.3 GO:0006397 mRNA processing(GO:0006397)
0.0 0.1 GO:0007143 female meiotic division(GO:0007143)
0.0 1.3 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 1.4 GO:0007338 single fertilization(GO:0007338)
0.0 2.1 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 1.5 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 1.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.6 GO:0009408 response to heat(GO:0009408)
0.0 4.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.3 GO:0010165 response to X-ray(GO:0010165)
0.0 0.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.8 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.8 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 2.7 GO:0006399 tRNA metabolic process(GO:0006399)
0.0 2.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.5 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.9 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.3 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.1 GO:0006821 chloride transport(GO:0006821)
0.0 1.3 GO:0060042 retina morphogenesis in camera-type eye(GO:0060042)
0.0 2.2 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 1.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.3 6.6 GO:0042584 chromaffin granule membrane(GO:0042584)
1.3 6.4 GO:0005879 axonemal microtubule(GO:0005879)
0.7 50.7 GO:0031514 motile cilium(GO:0031514)
0.7 5.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.6 6.5 GO:0030990 intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.4 3.0 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.4 21.4 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.4 1.6 GO:0005787 signal peptidase complex(GO:0005787)
0.4 2.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 5.6 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.3 4.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 1.5 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.2 7.5 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.2 0.8 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.2 1.3 GO:0036156 inner dynein arm(GO:0036156)
0.2 7.9 GO:0030286 dynein complex(GO:0030286)
0.2 2.3 GO:0097546 ciliary base(GO:0097546)
0.2 9.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 1.7 GO:0036449 microtubule minus-end(GO:0036449)
0.2 5.6 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 3.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 8.8 GO:0030175 filopodium(GO:0030175)
0.2 3.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 2.0 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 3.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 4.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 2.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.5 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.7 GO:0031430 M band(GO:0031430)
0.1 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 4.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 2.3 GO:0043204 perikaryon(GO:0043204)
0.0 9.7 GO:0005929 cilium(GO:0005929)
0.0 2.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 3.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.3 GO:0005871 kinesin complex(GO:0005871)
0.0 1.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
1.6 7.9 GO:0004127 cytidylate kinase activity(GO:0004127)
1.4 5.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.9 2.7 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.7 4.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.5 1.5 GO:0070097 delta-catenin binding(GO:0070097)
0.5 4.3 GO:0043515 kinetochore binding(GO:0043515)
0.5 5.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.4 2.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.4 2.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 6.9 GO:0097602 cullin family protein binding(GO:0097602)
0.3 3.6 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.3 18.4 GO:0005178 integrin binding(GO:0005178)
0.3 6.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 3.8 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.3 4.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 3.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 3.2 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.2 3.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.2 0.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 9.6 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.2 1.9 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 2.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 0.5 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 2.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 6.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 8.8 GO:0030674 protein binding, bridging(GO:0030674)
0.1 1.7 GO:0030507 spectrin binding(GO:0030507) microtubule minus-end binding(GO:0051011)
0.1 4.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 3.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 3.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 2.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.8 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 7.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.4 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.1 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 6.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 23.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 9.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 18.8 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 2.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 3.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 33.5 GO:0030234 enzyme regulator activity(GO:0030234)
0.0 4.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 3.3 GO:0000149 SNARE binding(GO:0000149)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.3 GO:0042562 hormone binding(GO:0042562)
0.0 1.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 4.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 1.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0042803 protein homodimerization activity(GO:0042803)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 17.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 7.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 3.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 3.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.3 3.0 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 17.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 3.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 1.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 2.3 REACTOME KINESINS Genes involved in Kinesins
0.1 1.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes