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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for rx3

Z-value: 0.72

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Transcription factors associated with rx3

Gene Symbol Gene ID Gene Info
rx3
ENSDARG00000052893 retinal homeobox gene 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rx3dr11_v1_chr21_+_10756154_10756154-0.355.5e-04Click!

Activity profile of rx3 motif

Sorted Z-values of rx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_35633827 10.87 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr2_-_15324837 10.56 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr13_+_22480496 9.87 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr10_-_21362320 9.85 ENSDART00000189789
avd
avidin
chr20_-_23426339 9.71 ENSDART00000004625
zar1
zygote arrest 1
chr10_-_21362071 9.47 ENSDART00000125167
avd
avidin
chr13_+_22479988 9.23 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr21_+_25777425 8.36 ENSDART00000021620
cldnd
claudin d
chr1_-_18811517 8.08 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr10_-_34002185 7.38 ENSDART00000046599
zar1l
zygote arrest 1-like
chr24_+_12835935 6.14 ENSDART00000114762
nanog
nanog homeobox
chr2_+_6253246 6.12 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr8_+_45334255 6.12 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr11_-_44801968 5.92 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr18_-_40708537 5.89 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr19_-_25119443 5.82 ENSDART00000148953
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr25_-_10503043 5.72 ENSDART00000155404
cox8b
cytochrome c oxidase subunit 8b
chr20_-_40755614 5.52 ENSDART00000061247
cx32.3
connexin 32.3
chr16_-_42056137 5.41 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr10_+_6884627 5.37 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr16_-_42894628 4.57 ENSDART00000045600
hfe2
hemochromatosis type 2
chr12_-_33357655 4.17 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr24_+_1023839 3.76 ENSDART00000082526
zgc:111976
zgc:111976
chr10_+_6884123 3.72 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr3_+_23692462 3.37 ENSDART00000145934
hoxb7a
homeobox B7a
chr1_-_513762 3.35 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr21_+_28478663 3.18 ENSDART00000077887
ENSDART00000134150
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr13_+_28701233 2.93 ENSDART00000135931
si:ch211-67n3.9
si:ch211-67n3.9
chr14_-_858985 2.77 ENSDART00000148687
ENSDART00000149375
slc34a1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr15_-_23376541 2.73 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr4_-_4834617 2.68 ENSDART00000141539
coa6
cytochrome c oxidase assembly factor 6
chr10_+_36178713 2.59 ENSDART00000140816
or108-3
odorant receptor, family D, subfamily 108, member 3
chr10_-_7756865 2.59 ENSDART00000114373
ENSDART00000125407
ENSDART00000016317
loxa
lysyl oxidase a
chr19_-_8768564 2.58 ENSDART00000170416
si:ch73-350k19.1
si:ch73-350k19.1
chr17_+_8799661 2.45 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr10_-_13343831 2.45 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr9_-_50001606 2.37 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr12_-_35830625 2.36 ENSDART00000180028
CU459056.1

chr13_+_38814521 2.31 ENSDART00000110976
col19a1
collagen, type XIX, alpha 1
chr23_-_17003533 2.21 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr1_+_35985813 2.21 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr12_+_48803098 2.19 ENSDART00000074768
ppifb
peptidylprolyl isomerase Fb
chr8_+_20776654 2.12 ENSDART00000135850
nfic
nuclear factor I/C
chr9_+_22364997 2.09 ENSDART00000188054
ENSDART00000046116
crygs3
crystallin, gamma S3
chr18_+_20560442 2.07 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr15_+_31344472 2.02 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
or107-1
odorant receptor, family D, subfamily 107, member 1
chr14_+_34490445 1.97 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr25_-_27621268 1.88 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr9_+_50001746 1.86 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr9_-_19161982 1.84 ENSDART00000081878
pou1f1
POU class 1 homeobox 1
chr15_-_21877726 1.83 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr12_-_6880694 1.77 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr10_+_42423318 1.75 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr4_+_306036 1.73 ENSDART00000103659
msgn1
mesogenin 1
chr4_-_4834347 1.66 ENSDART00000141803
coa6
cytochrome c oxidase assembly factor 6
chr17_-_10122204 1.66 ENSDART00000160751
BX088587.1

chr2_+_39021282 1.65 ENSDART00000056577
RBP1 (1 of many)
si:ch211-119o8.7
chr14_-_8940499 1.55 ENSDART00000129030
zgc:153681
zgc:153681
chr17_+_8799451 1.55 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr9_-_21912227 1.54 ENSDART00000145576
lmo7a
LIM domain 7a
chr5_-_27438812 1.52 ENSDART00000078755
drd7
dopamine receptor D7
chr14_+_36521005 1.49 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr17_+_26352372 1.49 ENSDART00000155177
grid1a
glutamate receptor, ionotropic, delta 1a
chr24_-_25144441 1.47 ENSDART00000152104
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr17_+_46818521 1.45 ENSDART00000156022
pimr14
Pim proto-oncogene, serine/threonine kinase, related 14
chr10_+_21867307 1.43 ENSDART00000126629
cbln17
cerebellin 17
chr17_+_37227936 1.36 ENSDART00000076009
hadhab
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
chr16_-_35975254 1.34 ENSDART00000167537
eva1ba
eva-1 homolog Ba (C. elegans)
chr5_-_50992690 1.32 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr16_-_16761164 1.31 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr5_-_67629263 1.29 ENSDART00000133753
zbtb20
zinc finger and BTB domain containing 20
chr11_+_31864921 1.29 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr3_-_50443607 1.28 ENSDART00000074036
rcvrna
recoverin a
chr22_+_28337429 1.28 ENSDART00000166177
impg2b
interphotoreceptor matrix proteoglycan 2b
chr20_-_40758410 1.25 ENSDART00000183031
cx34.5
connexin 34.5
chr22_+_28337204 1.23 ENSDART00000163352
impg2b
interphotoreceptor matrix proteoglycan 2b
chr6_+_24398907 1.20 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr14_+_40874608 1.19 ENSDART00000168448
si:ch211-106m9.1
si:ch211-106m9.1
chr14_-_2933185 1.19 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr6_-_40352215 1.17 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr23_-_19230627 1.09 ENSDART00000007122
guca1b
guanylate cyclase activator 1B
chr6_+_41191482 1.06 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr1_-_5455498 1.04 ENSDART00000040368
ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr24_-_35282568 0.98 ENSDART00000167406
ENSDART00000088609
sntg1
syntrophin, gamma 1
chr24_-_4782052 0.96 ENSDART00000149911
agtr1b
angiotensin II receptor, type 1b
chr7_-_23768234 0.93 ENSDART00000173981
si:ch211-200p22.4
si:ch211-200p22.4
chr10_-_2971407 0.90 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr3_+_13929860 0.89 ENSDART00000164179
syce2
synaptonemal complex central element protein 2
chr1_-_17715493 0.86 ENSDART00000133027
si:dkey-256e7.8
si:dkey-256e7.8
chr24_+_13316737 0.85 ENSDART00000191658
SBSPON
somatomedin B and thrombospondin type 1 domain containing
chr4_-_20292821 0.77 ENSDART00000136069
ENSDART00000192504
cacna2d4a
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr16_+_27383717 0.74 ENSDART00000132329
ENSDART00000136256
stx17
syntaxin 17
chr18_+_48423973 0.74 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr20_+_28861629 0.72 ENSDART00000187274
ENSDART00000047826
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr8_+_17168114 0.72 ENSDART00000183901
cenph
centromere protein H
chr16_+_31804590 0.67 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr7_+_34592526 0.66 ENSDART00000173959
fhod1
formin homology 2 domain containing 1
chr10_-_32494304 0.64 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr10_+_39212898 0.64 ENSDART00000159501
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr10_+_39212601 0.63 ENSDART00000168778
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr20_-_9095105 0.63 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr13_-_31017960 0.62 ENSDART00000145287
wdfy4
WDFY family member 4
chr22_+_18477934 0.52 ENSDART00000132684
cilp2
cartilage intermediate layer protein 2
chr16_+_33902006 0.51 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr6_+_21001264 0.49 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr22_+_13917311 0.48 ENSDART00000022654
sh3bp4a
SH3-domain binding protein 4a
chr10_-_32494499 0.46 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr5_+_32009542 0.42 ENSDART00000182025
ENSDART00000179879
scai
suppressor of cancer cell invasion
chr23_-_1348933 0.41 ENSDART00000168981
CABZ01078120.1

chr13_-_44630111 0.41 ENSDART00000110092
mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr2_-_30668580 0.40 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr25_-_13490744 0.38 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr20_+_28861435 0.35 ENSDART00000142678
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr21_+_32820175 0.35 ENSDART00000076903
adra2db
adrenergic, alpha-2D-, receptor b
chr11_+_33312601 0.33 ENSDART00000188024
cntnap5l
contactin associated protein-like 5 like
chr8_+_6410933 0.32 ENSDART00000168789
lrrtm4l2
leucine rich repeat transmembrane neuronal 4 like 2
chr8_+_7801060 0.32 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr18_-_5598958 0.30 ENSDART00000161538
cyp1a
cytochrome P450, family 1, subfamily A
chr4_+_3980247 0.28 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr1_-_26444075 0.23 ENSDART00000125690
ints12
integrator complex subunit 12
chr15_-_14552101 0.19 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr18_-_43884044 0.16 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr24_+_19415124 0.14 ENSDART00000186931
sulf1
sulfatase 1
chr21_-_37973819 0.12 ENSDART00000133405
ripply1
ripply transcriptional repressor 1
chr21_-_22827548 0.12 ENSDART00000079161
angptl5
angiopoietin-like 5
chr8_-_39822917 0.10 ENSDART00000067843
zgc:162025
zgc:162025
chr21_-_32060993 0.09 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr19_+_10339538 0.09 ENSDART00000151808
ENSDART00000151235
rcvrn3
recoverin 3
chr8_+_25034544 0.07 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr15_-_2184638 0.06 ENSDART00000135460
shox2
short stature homeobox 2
chr24_-_31425799 0.03 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr5_+_66433287 0.02 ENSDART00000170757
kntc1
kinetochore associated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of rx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.3 3.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.7 2.1 GO:0060631 regulation of meiosis I(GO:0060631)
0.7 11.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.7 3.4 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.7 2.0 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.6 1.7 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.6 9.1 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.5 2.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.4 2.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.4 1.8 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.3 10.6 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.3 5.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 4.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.2 2.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.2 4.0 GO:0031297 replication fork processing(GO:0031297)
0.2 2.6 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 1.8 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.5 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.1 1.4 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 6.1 GO:0060968 regulation of gene silencing(GO:0060968)
0.1 0.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 17.2 GO:0001756 somitogenesis(GO:0001756)
0.1 1.3 GO:0043687 post-translational protein modification(GO:0043687)
0.1 1.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 8.4 GO:0017148 negative regulation of translation(GO:0017148)
0.1 5.7 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 1.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.6 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 1.3 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.1 4.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 0.7 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.8 GO:0046549 retinal cone cell development(GO:0046549)
0.0 1.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.0 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.0 0.1 GO:0097065 anterior head development(GO:0097065)
0.0 6.8 GO:0007601 visual perception(GO:0007601)
0.0 1.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.2 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.7 GO:0051784 negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 1.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 7.4 GO:0006412 translation(GO:0006412)
0.0 1.8 GO:0001708 cell fate specification(GO:0001708)
0.0 2.4 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 2.1 GO:0006260 DNA replication(GO:0006260)
0.0 1.5 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0097189 apoptotic body(GO:0097189)
0.6 4.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 2.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.4 3.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4 19.1 GO:0031941 filamentous actin(GO:0031941)
0.3 5.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.3 9.1 GO:0043186 P granule(GO:0043186)
0.2 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.2 6.7 GO:0000421 autophagosome membrane(GO:0000421)
0.2 6.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.9 GO:0000801 central element(GO:0000801)
0.1 2.8 GO:0005903 brush border(GO:0005903)
0.1 1.8 GO:0042627 chylomicron(GO:0042627)
0.1 0.9 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.8 GO:0032420 stereocilium(GO:0032420)
0.1 3.8 GO:0016592 mediator complex(GO:0016592)
0.1 8.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.5 GO:0045180 basal cortex(GO:0045180)
0.0 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 13.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.2 GO:0005930 axoneme(GO:0005930)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.3 GO:0009374 biotin binding(GO:0009374)
1.0 19.1 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.8 3.4 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.8 3.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.7 11.5 GO:0032190 acrosin binding(GO:0032190)
0.5 1.5 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.5 2.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.5 1.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4 6.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 1.2 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.4 1.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 4.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 1.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.0 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.2 5.7 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 2.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 2.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 10.6 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 1.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 2.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 9.3 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 5.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.6 GO:0005109 frizzled binding(GO:0005109)
0.1 14.8 GO:0042802 identical protein binding(GO:0042802)
0.1 0.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 15.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 1.5 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 2.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.2 GO:0004527 exonuclease activity(GO:0004527)
0.0 2.2 GO:0019838 growth factor binding(GO:0019838)
0.0 1.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 5.0 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0050661 NADP binding(GO:0050661)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 1.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.3 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation