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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for rxraa+rxrab+rxrba+rxrgb

Z-value: 1.14

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Transcription factors associated with rxraa+rxrab+rxrba+rxrgb

Gene Symbol Gene ID Gene Info
ENSDARG00000004697 retinoid X receptor, gamma b
ENSDARG00000035127 retinoid x receptor, alpha b
ENSDARG00000057737 retinoid X receptor, alpha a
ENSDARG00000078954 retinoid x receptor, beta a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rxrgbdr11_v1_chr20_+_33875256_338752560.481.0e-06Click!
rxrbadr11_v1_chr19_-_7272921_7273057-0.381.5e-04Click!
rxrabdr11_v1_chr5_-_64511428_64511428-0.241.9e-02Click!
rxraadr11_v1_chr21_+_17768174_177681740.188.2e-02Click!

Activity profile of rxraa+rxrab+rxrba+rxrgb motif

Sorted Z-values of rxraa+rxrab+rxrba+rxrgb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_19006631 18.77 ENSDART00000080269
ENSDART00000191682
phosphoglycerate mutase 2 (muscle)
chr7_+_34297271 18.53 ENSDART00000180342
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr13_+_50375800 17.18 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr7_+_34296789 14.52 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr6_+_60055168 13.14 ENSDART00000008752
phosphoenolpyruvate carboxykinase 1 (soluble)
chr2_-_39017838 12.26 ENSDART00000048838
retinol binding protein 2b, cellular
chr22_+_38229321 11.55 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
chr22_-_7050 11.06 ENSDART00000127829
ATPase family, AAA domain containing 3
chr22_-_23612854 10.94 ENSDART00000165885
complement factor H like 5
chr12_-_6033824 10.91 ENSDART00000131301
ENSDART00000139419
ENSDART00000032050
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 1
chr20_+_15015557 10.73 ENSDART00000039345
myocilin
chr11_+_11201096 10.63 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr18_-_17415580 10.44 ENSDART00000150077
ENSDART00000100190
carboxylesterase 2 (intestine, liver)
chr3_-_18805225 9.93 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr21_+_20771082 9.60 ENSDART00000079732
3-oxoacid CoA transferase 1b
chr5_-_36837846 9.57 ENSDART00000032481
creatine kinase, muscle a
chr11_+_18037729 9.17 ENSDART00000111624
zgc:175135
chr11_-_22303678 8.92 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr2_+_42191592 8.89 ENSDART00000144716
caveolae associated protein 4a
chr7_-_52096498 8.85 ENSDART00000098688
ENSDART00000098690
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr17_+_450956 8.79 ENSDART00000183022
ENSDART00000171386
zgc:194887
chr23_-_12788113 8.78 ENSDART00000103231
ENSDART00000146640
ENSDART00000180549
si:dkey-96f10.1
chr18_+_1615 8.71 ENSDART00000082450
homer scaffolding protein 2
chr9_-_22834860 8.71 ENSDART00000146486
nebulin
chr11_+_18157260 8.46 ENSDART00000144659
zgc:173545
chr8_-_37263524 8.44 ENSDART00000061327
Rh50-like protein
chr5_-_69940868 8.35 ENSDART00000185924
ENSDART00000097357
UDP glucuronosyltransferase 2 family, polypeptide A4
chr20_+_47953047 8.13 ENSDART00000079734
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
chr11_+_18053333 7.99 ENSDART00000075750
zgc:175135
chr19_-_41213718 7.98 ENSDART00000077121
pyruvate dehydrogenase kinase, isozyme 4
chr8_-_65189 7.62 ENSDART00000168412
hydroxysteroid (17-beta) dehydrogenase 4
chr11_+_18130300 7.61 ENSDART00000169146
zgc:175135
chr2_+_22659787 7.40 ENSDART00000043956
zgc:161973
chr20_+_54304800 7.40 ENSDART00000121661
zona pellucida glycoprotein 2, tandem duplicate 6
chr19_+_40861853 7.37 ENSDART00000126470
zgc:85777
chr20_-_25522911 7.35 ENSDART00000063058
cytochrome P450, family 2, subfamily N, polypeptide 13
chr15_-_6946286 7.27 ENSDART00000019330
enoyl CoA hydratase 1, peroxisomal
chr14_-_48103207 7.25 ENSDART00000056712
electron-transferring-flavoprotein dehydrogenase
chr12_-_5120175 7.15 ENSDART00000160729
retinol binding protein 4, plasma
chr20_+_54312970 7.09 ENSDART00000024598
ENSDART00000193172
zona pellucida glycoprotein 2, tandem duplicate 5
chr12_-_5120339 6.92 ENSDART00000168759
retinol binding protein 4, plasma
chr3_+_12732382 6.84 ENSDART00000158403
cytochrome P450, family 2, subfamily k, polypeptide 19
chr3_+_39566999 6.83 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr20_+_54309148 6.79 ENSDART00000099360
zona pellucida glycoprotein 2, tandem duplicate 1
chr21_+_25777425 6.70 ENSDART00000021620
claudin d
chr7_+_69019851 6.68 ENSDART00000162891

chr6_-_59563597 6.56 ENSDART00000166311
inhibin beta E subunit
chr20_+_54295213 6.51 ENSDART00000074085
zona pellucida glycoprotein 2, tandem duplicate 3
chr20_+_54299419 6.44 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
chr11_+_77526 6.36 ENSDART00000193521

chr5_-_1962500 6.17 ENSDART00000150163
ribosomal protein, large, P0
chr7_-_52096287 6.11 ENSDART00000174068
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr13_-_34683370 6.04 ENSDART00000113661
kinesin family member 16Bb
chr9_+_33216945 6.00 ENSDART00000134029
si:ch211-125e6.12
chr22_-_20126230 5.99 ENSDART00000138688
cAMP responsive element binding protein 3-like 3a
chr9_-_43082945 5.95 ENSDART00000142257
coiled-coil domain containing 141
chr7_-_51953613 5.93 ENSDART00000142042
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr7_-_24046999 5.90 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dehydrogenase/reductase (SDR family) member 4
chr8_-_2529878 5.88 ENSDART00000056767
acetyl-CoA acyltransferase 2
chr22_-_38274188 5.84 ENSDART00000139420
ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr11_+_18175893 5.81 ENSDART00000177625
zgc:173545
chr13_+_829585 5.81 ENSDART00000029051
glutathione S-transferase, alpha tandem duplicate 2
chr7_-_17337233 5.80 ENSDART00000050236
ENSDART00000102141
novel immune-type receptor 8
chr24_-_11446156 5.78 ENSDART00000143921
ENSDART00000066778
acyl-CoA dehydrogenase family, member 11
chr19_+_46113828 5.73 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr22_-_5171362 5.68 ENSDART00000124889
tumor necrosis factor, alpha-induced protein 8-like 1
chr2_-_26476030 5.61 ENSDART00000145262
ENSDART00000132125
acyl-CoA dehydrogenase medium chain
chr2_-_57076687 5.55 ENSDART00000161523
solute carrier family 25, member 42
chr3_+_1749793 5.53 ENSDART00000149308
si:dkeyp-52c3.7
chr3_+_12744083 5.36 ENSDART00000158554
ENSDART00000169545
cytochrome P450, family 2, subfamily k, polypeptide 21
chr19_-_27564458 5.35 ENSDART00000123155
si:dkeyp-46h3.6
chr9_+_35077546 5.16 ENSDART00000142688
si:dkey-192g7.3
chr20_+_572037 5.16 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
SET and MYND domain containing 2b
chr20_-_47953524 5.13 ENSDART00000167986
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr1_-_9641845 5.11 ENSDART00000121490
ENSDART00000159411
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
chr3_+_27770110 4.99 ENSDART00000017962
enoyl-CoA delta isomerase 1
chr18_+_44769027 4.98 ENSDART00000145190
ilvB (bacterial acetolactate synthase)-like
chr7_-_24520866 4.83 ENSDART00000077039
fatty acid amide hydrolase 2b
chr24_+_2961098 4.80 ENSDART00000163760
ENSDART00000170835
enoyl-CoA delta isomerase 2
chr16_-_23800484 4.80 ENSDART00000139964
ribosomal protein S27, isoform 2
chr17_-_32370047 4.71 ENSDART00000145487
Kruppel-like factor 11b
chr7_+_31871830 4.64 ENSDART00000139899
myosin binding protein C, cardiac
chr19_+_7043634 4.56 ENSDART00000133954
major histocompatibility complex class I UKA
chr7_+_71664624 4.54 ENSDART00000170273
elastin microfibril interfacer 2b
chr15_-_16884912 4.49 ENSDART00000062135
zgc:103681
chr16_-_19568388 4.48 ENSDART00000141616
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr1_-_58868306 4.42 ENSDART00000166615
dynamin 2b
chr3_+_16922226 4.42 ENSDART00000017646
ATPase H+ transporting V0 subunit a1a
chr12_-_47774807 4.41 ENSDART00000193831

chr19_+_32166702 4.36 ENSDART00000021798
fatty acid binding protein 11a
chr17_+_51906053 4.27 ENSDART00000159072
ENSDART00000056869
feline leukemia virus subgroup C cellular receptor family, member 2a
chr8_+_11687254 4.26 ENSDART00000042040
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr20_-_48604621 4.23 ENSDART00000161769
ENSDART00000157871
microsomal glutathione S-transferase 3a
chr5_+_43870389 4.23 ENSDART00000141002
zgc:112966
chr5_+_6670945 4.22 ENSDART00000185686
paxillin a
chr10_-_690072 4.22 ENSDART00000164871
ENSDART00000142833
GLIS family zinc finger 3
chr11_-_29996344 4.21 ENSDART00000003712
ENSDART00000126110
angiotensin I converting enzyme 2
chr1_-_9644630 4.21 ENSDART00000123725
ENSDART00000161164
UDP glucuronosyltransferase 5 family, polypeptide B3
chr15_+_404891 4.17 ENSDART00000155682
nipsnap homolog 2
chr23_+_42434348 4.02 ENSDART00000161027
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr21_-_1640547 3.99 ENSDART00000151041
zgc:152948
chr3_-_34561624 3.99 ENSDART00000129313
septin 9a
chr24_-_7587401 3.99 ENSDART00000093163
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr25_+_36347126 3.98 ENSDART00000152449
si:ch211-113a14.22
chr20_-_48604199 3.97 ENSDART00000161762
ENSDART00000170894
microsomal glutathione S-transferase 3a
chr16_-_24612871 3.94 ENSDART00000155614
ENSDART00000154787
ENSDART00000155983
ENSDART00000156519
FXYD domain containing ion transport regulator 6 like
chr23_+_19790962 3.93 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr18_+_39487486 3.91 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr20_+_35445462 3.90 ENSDART00000124497
tudor domain containing 6
chr1_-_49505449 3.90 ENSDART00000187294
ENSDART00000132171
si:dkeyp-80c12.5
chr23_-_45705525 3.88 ENSDART00000148959
endothelin receptor type Ab
chr21_-_5879897 3.87 ENSDART00000184034
ribosomal protein L35
chr23_-_10696626 3.86 ENSDART00000177571
forkhead box P1a
chr24_+_81527 3.86 ENSDART00000192139
reversion-inducing-cysteine-rich protein with kazal motifs
chr6_-_7082108 3.83 ENSDART00000081760
Indian hedgehog homolog b
chr14_+_34495216 3.78 ENSDART00000147756
wingless-type MMTV integration site family, member 8a
chr7_+_31838320 3.77 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
myosin binding protein C, cardiac
chr6_+_153146 3.73 ENSDART00000097468
zinc finger, GATA-like protein 1
chr21_+_5080789 3.73 ENSDART00000024199
ATP synthase F1 subunit alpha
chr23_-_46040618 3.68 ENSDART00000161415

chr3_+_12718100 3.68 ENSDART00000162343
ENSDART00000192425
cytochrome P450, family 2, subfamily k, polypeptide 20
chr17_+_53297822 3.66 ENSDART00000168297
DEAD (Asp-Glu-Ala-Asp) box helicase 24
chr22_-_26834043 3.65 ENSDART00000087202
si:dkey-44g23.5
chr6_+_60036767 3.64 ENSDART00000155009
transglutaminase 8
chr18_-_15771551 3.64 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
chr5_-_36549024 3.62 ENSDART00000097671
zgc:158432
chr23_-_44903048 3.61 ENSDART00000149103
FH2 domain containing 5
chr11_+_24313931 3.55 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr9_+_8380728 3.54 ENSDART00000133501
si:ch1073-75o15.4
chr11_+_29965822 3.48 ENSDART00000127049
interleukin-1 family member A
chr13_-_25199260 3.46 ENSDART00000057605
adenosine kinase a
chr3_-_36419641 3.43 ENSDART00000173545
component of oligomeric golgi complex 1
chr21_+_29179887 3.43 ENSDART00000161941
si:ch211-57b15.1
chr17_+_30546579 3.37 ENSDART00000154385
NHS-like 1a
chr8_+_48491387 3.33 ENSDART00000086053
si:ch211-263k4.2
chr7_-_51953807 3.32 ENSDART00000174102
ENSDART00000145645
ENSDART00000052054
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr3_+_25999477 3.31 ENSDART00000024316
minichromosome maintenance complex component 5
chr2_-_37744951 3.30 ENSDART00000144807
myosin IXb
chr3_+_4346854 3.29 ENSDART00000004273
si:dkey-73p2.3
chr13_-_40726865 3.29 ENSDART00000099847
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr24_-_26820698 3.26 ENSDART00000147788
fibronectin type III domain containing 3Bb
chr15_+_5088210 3.25 ENSDART00000183423
myxovirus (influenza virus) resistance F
chr15_-_28082310 3.24 ENSDART00000152620
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr21_+_15704556 3.22 ENSDART00000024858
ENSDART00000146909
coiled-coil-helix-coiled-coil-helix domain containing 10
chr19_-_35439237 3.18 ENSDART00000145883
anillin, actin binding protein
chr23_+_44634187 3.18 ENSDART00000143688
si:ch73-265d7.2
chr6_-_48082525 3.10 ENSDART00000192049
solute carrier family 2 (facilitated glucose transporter), member 1b
chr21_-_30166097 3.10 ENSDART00000130676
heparin-binding EGF-like growth factor b
chr4_-_50926767 3.10 ENSDART00000183430
si:ch211-208f21.3
chr3_+_58167288 3.09 ENSDART00000155874
ENSDART00000010395
ubiquinol-cytochrome c reductase core protein 2a
chr18_-_34549721 3.09 ENSDART00000137101
ENSDART00000021880
signal sequence receptor, gamma
chr24_+_26742226 3.08 ENSDART00000079721
growth hormone secretagogue receptor b
chr8_+_32742650 3.06 ENSDART00000138117
hemicentin 2
chr6_+_1787160 3.05 ENSDART00000113505
myosin, light chain 9b, regulatory
chr12_-_36268723 3.05 ENSDART00000113740
potassium inwardly-rectifying channel, subfamily J, member 16
chr16_-_1503023 3.04 ENSDART00000036348
single-minded family bHLH transcription factor 1a
chr15_+_28268135 3.03 ENSDART00000152536
ENSDART00000188550
myosin Ic, paralog b
chr5_-_30984271 3.02 ENSDART00000051392
spinster homolog 3 (Drosophila)
chr2_+_57801960 3.01 ENSDART00000147966
si:dkeyp-68b7.10
chr13_+_844150 2.99 ENSDART00000058260
glutathione S-transferase, alpha tandem duplicate 1
chr2_-_24289641 2.99 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myosin heavy chain 7-like
chr22_+_18469004 2.98 ENSDART00000061430
cartilage intermediate layer protein 2
chr8_+_30664077 2.98 ENSDART00000138750
adenosine A2a receptor a
chr17_+_6538733 2.97 ENSDART00000193712
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr16_+_28602423 2.97 ENSDART00000182350
carnitine O-octanoyltransferase
chr1_-_56537347 2.97 ENSDART00000126054

chr11_-_45135643 2.91 ENSDART00000170863
calcium activated nucleotidase 1b
chr23_-_16737161 2.85 ENSDART00000132573
si:ch211-224l10.4
chr7_+_24520518 2.84 ENSDART00000173604
bloodthirsty-related gene family, member 9
chr5_-_30984010 2.81 ENSDART00000182367
spinster homolog 3 (Drosophila)
chr18_+_13315739 2.81 ENSDART00000143404
si:ch211-260p9.3
chr3_-_55531450 2.81 ENSDART00000155376
testis expressed 2
chr22_-_17595310 2.80 ENSDART00000099056
glutathione peroxidase 4a
chr8_+_31435452 2.73 ENSDART00000145282
selenoprotein P
chr10_+_11265387 2.71 ENSDART00000038888
hydroxysteroid dehydrogenase like 2
chr3_+_1179601 2.70 ENSDART00000173378
TRIO and F-actin binding protein b
chr15_+_15403560 2.69 ENSDART00000049831
dehydrogenase/reductase (SDR family) member 11b
chr23_-_1587955 2.67 ENSDART00000136037
fibronectin type III domain containing 7b
chr1_+_56955349 2.67 ENSDART00000152758
si:ch211-1f22.10
chr13_-_28688104 2.64 ENSDART00000133827
polycomb group ring finger 6
chr1_+_57145072 2.61 ENSDART00000152776
si:ch73-94k4.4
chr5_+_42141917 2.60 ENSDART00000172201
ENSDART00000140743
transient receptor potential cation channel, subfamily V, member 1
chr4_-_14531687 2.60 ENSDART00000182093
ENSDART00000159447
plexin b2a
chr14_-_28052474 2.60 ENSDART00000172948
ENSDART00000135337
si:ch211-220e11.3
zgc:64189
chr22_-_14262115 2.55 ENSDART00000168264
si:ch211-246m6.5
chr1_-_46859398 2.54 ENSDART00000135795
1-acylglycerol-3-phosphate O-acyltransferase 3
chr22_+_38778649 2.53 ENSDART00000075873
alkaline phosphatase, intestinal, tandem duplicate 2
chr2_-_31686353 2.53 ENSDART00000126177
ENSDART00000056679
E2F transcription factor 5
chr12_+_1286642 2.50 ENSDART00000157467
phosphatidylethanolamine N-methyltransferase
chr4_-_31064105 2.48 ENSDART00000157670
si:dkey-11n14.1
chr1_+_57176256 2.48 ENSDART00000152741
si:dkey-27j5.6
chr3_+_3810919 2.47 ENSDART00000056035

chr5_+_38631687 2.47 ENSDART00000147280
si:ch211-271e10.6
chr17_-_12196865 2.47 ENSDART00000154694
kinesin family member 28
chr21_+_14511685 2.46 ENSDART00000102099

chr8_+_999421 2.46 ENSDART00000149528
fatty acid binding protein 1b, tandem duplicate 1
chr8_-_4097722 2.45 ENSDART00000135006
cut-like homeobox 2b
chr24_-_25186895 2.42 ENSDART00000081029
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_+_58312187 2.39 ENSDART00000142285
si:dkey-222h21.10
chr14_+_30340251 2.38 ENSDART00000148448
microtubule associated tumor suppressor 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of rxraa+rxrab+rxrba+rxrgb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 34.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
3.3 13.1 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
2.4 7.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
2.0 14.1 GO:0034633 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
1.9 9.6 GO:0046952 ketone body catabolic process(GO:0046952)
1.7 8.4 GO:0003210 cardiac atrium formation(GO:0003210)
1.7 6.6 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
1.5 8.7 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
1.3 6.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.3 17.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.3 3.9 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
1.3 3.8 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
1.2 3.5 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
1.1 8.7 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
1.1 4.3 GO:0097037 heme export(GO:0097037)
1.1 8.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
1.0 3.0 GO:0072020 proximal straight tubule development(GO:0072020)
1.0 38.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.9 1.8 GO:0055057 neuroblast division(GO:0055057)
0.9 44.3 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.8 3.2 GO:0008356 asymmetric cell division(GO:0008356)
0.7 3.0 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.7 3.0 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) vitamin transmembrane transport(GO:0035461) coenzyme transport(GO:0051182)
0.7 3.7 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.7 18.8 GO:0007520 myoblast fusion(GO:0007520)
0.7 3.5 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.7 11.1 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.6 3.9 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.6 5.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.6 3.8 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.6 3.5 GO:0044209 AMP salvage(GO:0044209)
0.6 1.7 GO:1903961 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.5 8.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.5 2.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.4 1.8 GO:0003161 cardiac conduction system development(GO:0003161) negative regulation of heart rate(GO:0010459)
0.4 8.9 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.4 1.3 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.4 3.1 GO:0043589 skin morphogenesis(GO:0043589) mesenchymal cell migration(GO:0090497)
0.4 7.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.4 1.2 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.4 5.7 GO:0061055 myotome development(GO:0061055)
0.4 3.7 GO:0045444 fat cell differentiation(GO:0045444)
0.4 3.9 GO:0030719 P granule organization(GO:0030719)
0.3 3.1 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.3 4.4 GO:0001845 phagolysosome assembly(GO:0001845)
0.3 2.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 4.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3 1.0 GO:0044771 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.3 3.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3 6.8 GO:0001966 thigmotaxis(GO:0001966)
0.3 1.3 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.3 2.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.3 3.3 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 5.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 1.6 GO:0016559 peroxisome fission(GO:0016559)
0.3 1.9 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.3 1.4 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.3 6.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 2.3 GO:0006833 water transport(GO:0006833)
0.3 2.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 14.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.2 0.7 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.2 0.7 GO:0061355 Wnt protein secretion(GO:0061355)
0.2 1.8 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 1.8 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 24.5 GO:0048545 response to steroid hormone(GO:0048545)
0.2 6.5 GO:0003323 type B pancreatic cell development(GO:0003323)
0.2 2.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 8.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 4.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.4 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.2 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.2 5.5 GO:0048599 oocyte development(GO:0048599)
0.2 2.6 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 3.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 1.9 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 3.2 GO:0042574 retinal metabolic process(GO:0042574)
0.2 1.8 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.2 0.8 GO:0090342 regulation of cell aging(GO:0090342)
0.2 2.0 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.4 GO:1901998 toxin transport(GO:1901998)
0.1 3.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.1 5.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 11.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 1.3 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 2.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 2.6 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 6.0 GO:0019226 transmission of nerve impulse(GO:0019226)
0.1 4.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 2.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.7 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.2 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.7 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 2.2 GO:0051058 negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 10.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 0.5 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 3.1 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 4.3 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.1 1.8 GO:0009062 fatty acid catabolic process(GO:0009062)
0.1 1.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 7.4 GO:0030048 actin filament-based movement(GO:0030048)
0.1 0.5 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 3.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 5.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 4.3 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.1 1.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.3 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 4.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 1.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 4.5 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 0.3 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.1 2.3 GO:0043491 protein kinase B signaling(GO:0043491)
0.1 6.0 GO:0006334 nucleosome assembly(GO:0006334)
0.1 4.1 GO:1990266 neutrophil migration(GO:1990266)
0.1 1.0 GO:0001508 action potential(GO:0001508)
0.1 4.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.6 GO:0035065 regulation of histone acetylation(GO:0035065)
0.1 1.6 GO:0001878 response to yeast(GO:0001878)
0.1 1.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 10.7 GO:0030041 actin filament polymerization(GO:0030041)
0.1 4.0 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.1 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 2.2 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.0 GO:0097475 motor neuron migration(GO:0097475)
0.0 7.4 GO:0016042 lipid catabolic process(GO:0016042)
0.0 2.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 2.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 10.7 GO:0007005 mitochondrion organization(GO:0007005)
0.0 0.4 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.5 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 1.0 GO:0019835 cytolysis(GO:0019835)
0.0 7.4 GO:0006869 lipid transport(GO:0006869)
0.0 2.2 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 3.5 GO:0006954 inflammatory response(GO:0006954)
0.0 1.9 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 1.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 5.8 GO:0009617 response to bacterium(GO:0009617)
0.0 1.5 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 7.7 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.4 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 2.3 GO:0008033 tRNA processing(GO:0008033)
0.0 0.9 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 5.7 GO:0043066 negative regulation of apoptotic process(GO:0043066)
0.0 1.1 GO:0032880 regulation of protein localization(GO:0032880)
0.0 4.3 GO:0006955 immune response(GO:0006955)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.5 GO:0031638 zymogen activation(GO:0031638)
0.0 0.2 GO:0018149 peptide cross-linking(GO:0018149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0005948 acetolactate synthase complex(GO:0005948)
2.2 8.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
1.3 3.9 GO:0033391 chromatoid body(GO:0033391)
1.3 3.8 GO:0097189 apoptotic body(GO:0097189)
1.0 3.9 GO:1990909 Wnt signalosome(GO:1990909)
0.5 3.7 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.5 10.6 GO:0031430 M band(GO:0031430)
0.5 3.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 4.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4 1.6 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.4 7.7 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.3 5.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 10.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 2.2 GO:0001891 phagocytic cup(GO:0001891)
0.3 0.9 GO:0070545 PeBoW complex(GO:0070545)
0.3 2.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 3.4 GO:0017119 Golgi transport complex(GO:0017119)
0.2 4.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 0.6 GO:0030689 Noc complex(GO:0030689)
0.2 3.3 GO:0042555 MCM complex(GO:0042555)
0.2 0.7 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.2 10.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 6.2 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 23.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 7.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 13.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 112.6 GO:0005739 mitochondrion(GO:0005739)
0.1 2.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 4.8 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 4.0 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 3.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 4.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 7.7 GO:0005871 kinesin complex(GO:0005871)
0.1 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 10.4 GO:0016459 myosin complex(GO:0016459)
0.1 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.1 8.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 3.7 GO:0016342 catenin complex(GO:0016342)
0.1 1.0 GO:0005579 membrane attack complex(GO:0005579)
0.1 6.0 GO:0000786 nucleosome(GO:0000786)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 5.0 GO:0030018 Z disc(GO:0030018)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 90.6 GO:0005576 extracellular region(GO:0005576)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 7.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 2.1 GO:0031201 SNARE complex(GO:0031201)
0.0 3.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 1.4 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 33.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
3.8 18.8 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
2.7 8.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
2.5 7.6 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
2.5 9.9 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
2.4 7.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
2.2 6.6 GO:0003984 acetolactate synthase activity(GO:0003984)
2.0 14.1 GO:0034632 retinol transporter activity(GO:0034632)
2.0 5.9 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
1.9 9.6 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
1.9 5.7 GO:1990825 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
1.8 5.5 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
1.5 9.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.3 3.9 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.2 5.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
1.1 3.3 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.1 13.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
1.0 6.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.0 8.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.9 3.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.9 6.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.8 14.3 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.8 8.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.8 49.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.7 3.0 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.7 3.5 GO:0004001 adenosine kinase activity(GO:0004001)
0.6 3.2 GO:0016415 octanoyltransferase activity(GO:0016415)
0.6 8.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.6 17.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 3.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.5 2.7 GO:0008430 selenium binding(GO:0008430)
0.5 4.3 GO:0015232 heme transporter activity(GO:0015232)
0.5 17.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.4 2.2 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.4 3.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.4 1.3 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.4 3.8 GO:0005113 patched binding(GO:0005113)
0.4 3.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.4 3.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 13.1 GO:0030145 manganese ion binding(GO:0030145)
0.3 2.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 8.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 2.3 GO:0015250 water channel activity(GO:0015250)
0.3 3.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 5.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 2.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 3.3 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.3 3.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 4.4 GO:0051117 ATPase binding(GO:0051117)
0.3 11.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 4.9 GO:0035497 cAMP response element binding(GO:0035497)
0.3 4.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 13.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 1.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 4.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 1.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 1.1 GO:0042169 SH2 domain binding(GO:0042169)
0.2 2.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 6.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.7 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.2 2.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 2.4 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.2 1.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 4.0 GO:0005112 Notch binding(GO:0005112)
0.2 1.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 3.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 7.4 GO:0000146 microfilament motor activity(GO:0000146)
0.1 3.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 2.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 4.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.4 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 1.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.9 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 3.7 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 1.9 GO:0004875 complement receptor activity(GO:0004875)
0.1 3.8 GO:0005109 frizzled binding(GO:0005109)
0.1 1.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 2.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 4.8 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 5.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 1.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 5.8 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.7 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 6.8 GO:0005125 cytokine activity(GO:0005125)
0.0 11.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 7.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 8.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 2.9 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.3 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 2.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 4.7 GO:0003774 motor activity(GO:0003774)
0.0 0.7 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 4.0 GO:0060090 binding, bridging(GO:0060090)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.3 GO:0016209 antioxidant activity(GO:0016209)
0.0 5.7 GO:0016887 ATPase activity(GO:0016887)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.7 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 1.4 GO:0005319 lipid transporter activity(GO:0005319)
0.0 1.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.9 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.3 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 2.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 13.4 PID E2F PATHWAY E2F transcription factor network
0.1 3.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 2.3 ST GA12 PATHWAY G alpha 12 Pathway
0.1 2.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.1 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.9 PID ARF6 PATHWAY Arf6 signaling events
0.1 10.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
1.4 19.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.1 7.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.9 18.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.8 6.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.7 8.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 3.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 8.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 1.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 4.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 3.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 1.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 2.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 33.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 3.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 3.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 2.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 4.7 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 2.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 4.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 5.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 10.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 2.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI