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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b

Z-value: 0.46

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Transcription factors associated with six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b

Gene Symbol Gene ID Gene Info
six3b
ENSDARG00000054879 SIX homeobox 3b
six3a
ENSDARG00000058008 SIX homeobox 3a
six7
ENSDARG00000070107 SIX homeobox 7
six3a
ENSDARG00000114971 SIX homeobox 3a
six1a
ENSDARG00000039304 SIX homeobox 1a
six2b
ENSDARG00000054878 SIX homeobox 2b
six2a
ENSDARG00000058004 SIX homeobox 2a
six5
ENSDARG00000068406 SIX homeobox 5
six9
ENSDARG00000068407 SIX homeobox 9
six2a
ENSDARG00000115214 SIX homeobox 2a
six1b
ENSDARG00000026473 SIX homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
six1adr11_v1_chr13_-_31622195_31622195-0.521.1e-07Click!
six2bdr11_v1_chr12_-_25612170_25612170-0.503.2e-07Click!
six2adr11_v1_chr13_+_10232695_10232695-0.503.7e-07Click!
six1bdr11_v1_chr20_+_20499869_20499869-0.481.1e-06Click!
six3adr11_v1_chr13_-_10261383_10261383-0.187.7e-02Click!
six3bdr11_v1_chr12_+_25600685_25600685-0.122.5e-01Click!
six7dr11_v1_chr7_-_7420301_7420301-0.112.7e-01Click!
six9dr11_v1_chr18_-_37241080_37241115-0.103.5e-01Click!
six5dr11_v1_chr18_-_37252036_37252036-0.103.6e-01Click!

Activity profile of six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b motif

Sorted Z-values of six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_49283058 4.28 ENSDART00000076554
si:zfos-464b6.2
si:zfos-464b6.2
chr3_-_49815223 2.98 ENSDART00000181208
gcgra
glucagon receptor a
chr7_-_71486162 2.47 ENSDART00000045253
aco1
aconitase 1, soluble
chr5_+_9377005 1.96 ENSDART00000124924
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr10_+_42898103 1.77 ENSDART00000015872
zcchc9
zinc finger, CCHC domain containing 9
chr11_-_42750626 1.68 ENSDART00000130640
si:ch73-106k19.5
si:ch73-106k19.5
chr8_+_20440297 1.64 ENSDART00000189486
mknk2b
MAP kinase interacting serine/threonine kinase 2b
chr16_+_41060161 1.30 ENSDART00000141130
scap
SREBF chaperone
chr16_-_46567344 1.27 ENSDART00000127721
si:dkey-152b24.7
si:dkey-152b24.7
chr17_+_16429826 1.20 ENSDART00000136078
efcab11
EF-hand calcium binding domain 11
chr3_-_21094437 1.16 ENSDART00000153739
ENSDART00000109790
nlk1
nemo-like kinase, type 1
chr21_+_11385031 1.09 ENSDART00000040598
cel.2
carboxyl ester lipase, tandem duplicate 2
chr21_-_26028205 1.07 ENSDART00000034875
sdf2
stromal cell-derived factor 2
chr8_-_26961779 1.04 ENSDART00000099214
slc16a1b
solute carrier family 16 (monocarboxylate transporter), member 1b
chr23_+_39481537 1.03 ENSDART00000187222
mical1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr22_-_24967348 0.99 ENSDART00000153490
ENSDART00000084871
fam20cl
family with sequence similarity 20, member C like
chr14_-_38872536 0.98 ENSDART00000184315
ENSDART00000127479
gsr
glutathione reductase
chr14_+_22397251 0.97 ENSDART00000185239
ENSDART00000124072
ENSDART00000054977
atp7a
ATPase copper transporting alpha
chr21_-_27195256 0.89 ENSDART00000133152
ENSDART00000065401
zgc:110782
zgc:110782
chr11_-_44194132 0.85 ENSDART00000182954
ENSDART00000111271
CABZ01080074.1

chr14_-_38873095 0.84 ENSDART00000047050
ENSDART00000173285
ENSDART00000147521
gsr
glutathione reductase
chr11_-_41220794 0.78 ENSDART00000192895
mrps16
mitochondrial ribosomal protein S16
chr12_+_13742953 0.76 ENSDART00000152257
ppp1r16a
protein phosphatase 1, regulatory subunit 16A
chr9_-_18911608 0.74 ENSDART00000138785
si:dkey-239h2.3
si:dkey-239h2.3
chr12_+_13742778 0.71 ENSDART00000111401
ENSDART00000190552
ppp1r16a
protein phosphatase 1, regulatory subunit 16A
chr21_-_7940043 0.67 ENSDART00000099733
ENSDART00000136671
f2rl1.1
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr19_+_34230108 0.65 ENSDART00000141950
galnt12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr1_-_55896332 0.64 ENSDART00000147516
si:ch73-343l4.8
si:ch73-343l4.8
chr7_-_38183331 0.61 ENSDART00000149382
abcc12
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr10_+_35468978 0.61 ENSDART00000131984
phldb2a
pleckstrin homology-like domain, family B, member 2a
chr11_-_24016761 0.59 ENSDART00000153601
ENSDART00000067817
ENSDART00000170531
chia.3
chitinase, acidic.3
chr19_-_20403845 0.56 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr20_-_45709990 0.56 ENSDART00000027482
gpcpd1
glycerophosphocholine phosphodiesterase 1
chr1_-_24255149 0.55 ENSDART00000146960
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr13_+_9678427 0.55 ENSDART00000153907
sema4ga
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ga
chr24_-_36175365 0.51 ENSDART00000065338
pak1ip1
PAK1 interacting protein 1
chr1_-_21723329 0.51 ENSDART00000137138
si:ch211-134c9.2
si:ch211-134c9.2
chr2_+_49631850 0.51 ENSDART00000114274
ENSDART00000114516
si:dkey-53k12.18
si:dkey-53k12.18
chr2_-_51512294 0.50 ENSDART00000185287
si:ch211-9d9.8
si:ch211-9d9.8
chr25_-_21763750 0.48 ENSDART00000089596
tmem168b
transmembrane protein 168b
chr15_+_41815703 0.46 ENSDART00000059508
pxylp1
2-phosphoxylose phosphatase 1
chr4_+_74396786 0.46 ENSDART00000127501
ENSDART00000174347
zmp:0000001020
zmp:0000001020
chr3_+_1724941 0.45 ENSDART00000193402
BX321875.2

chr4_+_73672430 0.42 ENSDART00000174310
ENSDART00000150505
si:dkey-262g12.7
si:dkey-262g12.7
chr13_+_9678262 0.42 ENSDART00000111365
sema4ga
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ga
chr5_+_36900157 0.40 ENSDART00000183533
ENSDART00000051184
hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr8_+_14381272 0.38 ENSDART00000057642
acbd6
acyl-CoA binding domain containing 6
chr7_-_35708450 0.37 ENSDART00000193886
irx5a
iroquois homeobox 5a
chr5_+_36899691 0.35 ENSDART00000132322
hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr20_-_39735952 0.35 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tpd52l1
tumor protein D52-like 1
chr10_+_14488625 0.34 ENSDART00000026383
sigmar1
sigma non-opioid intracellular receptor 1
chr5_-_54395488 0.33 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr16_-_23797570 0.33 ENSDART00000077834
rps27.2
ribosomal protein S27, isoform 2
chr14_-_8814590 0.32 ENSDART00000106670
trmt112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr20_+_13783040 0.32 ENSDART00000115329
ENSDART00000152497
lpgat1
lysophosphatidylglycerol acyltransferase 1
chr17_+_132555 0.32 ENSDART00000158159
zgc:77287
zgc:77287
chr4_+_18782539 0.31 ENSDART00000101052
slc26a4
solute carrier family 26 (anion exchanger), member 4
chr4_+_18782840 0.30 ENSDART00000146450
slc26a4
solute carrier family 26 (anion exchanger), member 4
chr2_-_24270062 0.30 ENSDART00000192445
myh7
myosin heavy chain 7
chr10_+_23520952 0.30 ENSDART00000125317
zmp:0000000937
zmp:0000000937
chr2_+_6999369 0.30 ENSDART00000050597
xpr1b
xenotropic and polytropic retrovirus receptor 1b
chr25_+_3788074 0.30 ENSDART00000154008
chid1
chitinase domain containing 1
chr13_+_33368140 0.30 ENSDART00000033848
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr4_-_5317006 0.29 ENSDART00000150867
si:ch211-214j24.15
si:ch211-214j24.15
chr6_-_40352215 0.28 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr17_+_13099476 0.25 ENSDART00000012670
pnn
pinin, desmosome associated protein
chr10_+_40633990 0.22 ENSDART00000190489
ENSDART00000139474
si:ch211-238p8.31
si:ch211-238p8.31
chr18_+_33322515 0.22 ENSDART00000136603
v2ra18
vomeronasal 2 receptor, a18
chr16_-_11961325 0.22 ENSDART00000143845
si:ch73-296e2.3
si:ch73-296e2.3
chr11_+_24002503 0.22 ENSDART00000164702
chia.2
chitinase, acidic.2
chr5_-_26247973 0.20 ENSDART00000098527
erap1b
endoplasmic reticulum aminopeptidase 1b
chr25_+_192116 0.20 ENSDART00000153983
zgc:114188
zgc:114188
chr16_-_46567136 0.20 ENSDART00000159180
si:dkey-152b24.7
si:dkey-152b24.7
chr21_-_21465111 0.19 ENSDART00000141487
nectin3b
nectin cell adhesion molecule 3b
chr6_+_41181869 0.19 ENSDART00000002046
opn1mw1
opsin 1 (cone pigments), medium-wave-sensitive, 1
chr13_-_3324764 0.19 ENSDART00000102748
ENSDART00000114040
ubr2
ubiquitin protein ligase E3 component n-recognin 2
chr11_+_24339377 0.18 ENSDART00000133679
ENSDART00000135435
ENSDART00000017973
ENSDART00000131365
ENSDART00000186418
rbm39a
RNA binding motif protein 39a
chr20_+_34502606 0.18 ENSDART00000139739
gorab
golgin, rab6-interacting
chr13_-_18122333 0.18 ENSDART00000128748
washc2c
WASH complex subunit 2C
chr20_+_46237000 0.17 ENSDART00000125636
taar14a
trace amine associated receptor 14a
chr11_+_3575963 0.17 ENSDART00000077305
si:dkey-33m11.8
si:dkey-33m11.8
chr19_-_11949996 0.16 ENSDART00000163478
ENSDART00000167299
cpsf1
cleavage and polyadenylation specific factor 1
chr21_-_13972745 0.16 ENSDART00000143874
akna
AT-hook transcription factor
chr4_-_13502549 0.16 ENSDART00000140366
si:ch211-266a5.12
si:ch211-266a5.12
chr5_+_13326765 0.15 ENSDART00000090851
ydjc
YdjC chitooligosaccharide deacetylase homolog
chr24_-_12745222 0.15 ENSDART00000151836
si:ch211-196f5.9
si:ch211-196f5.9
chr2_-_36494308 0.14 ENSDART00000110378
BX901889.2

chr19_+_10485847 0.14 ENSDART00000135719
si:ch211-171h4.6
si:ch211-171h4.6
chr20_-_34127415 0.14 ENSDART00000010028
ptgs2b
prostaglandin-endoperoxide synthase 2b
chr8_+_7801060 0.13 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr11_+_1602916 0.13 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
si:dkey-40c23.2
si:dkey-40c23.3
chr24_+_30435164 0.13 ENSDART00000193877
dpyda.1
dihydropyrimidine dehydrogenase a, tandem duplicate 1
chr12_-_35095414 0.12 ENSDART00000153229
si:dkey-21e13.3
si:dkey-21e13.3
chr5_+_41477526 0.12 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr10_-_32610776 0.12 ENSDART00000017436
mogat2
monoacylglycerol O-acyltransferase 2
chr8_+_44478294 0.12 ENSDART00000006898
si:ch73-211l2.3
si:ch73-211l2.3
chr15_-_38218320 0.11 ENSDART00000152363
rhoga
ras homolog family member Ga
chr17_-_6600899 0.11 ENSDART00000154074
ENSDART00000180912
ANKRD66
si:ch211-189e2.2
chr6_-_18618106 0.11 ENSDART00000161562
znf207b
zinc finger protein 207, b
chr6_-_1514767 0.11 ENSDART00000067586
chchd6b
coiled-coil-helix-coiled-coil-helix domain containing 6b
chr13_+_25549425 0.10 ENSDART00000087553
ENSDART00000169199
sec23ip
SEC23 interacting protein
chr4_-_49720388 0.09 ENSDART00000154146
znf1057
zinc finger protein 1057
chr20_-_44460789 0.09 ENSDART00000085442
mut
methylmalonyl CoA mutase
chr14_-_1355544 0.09 ENSDART00000060417
cetn4
centrin 4
chr4_-_5332814 0.09 ENSDART00000144225
osgep
O-sialoglycoprotein endopeptidase
chr14_+_1355857 0.09 ENSDART00000188008
bbs12
Bardet-Biedl syndrome 12
chr6_+_52947699 0.08 ENSDART00000180913
uba7
ubiquitin-like modifier activating enzyme 7
chr19_-_22664128 0.08 ENSDART00000136295
eif3eb
eukaryotic translation initiation factor 3, subunit E, b
chr12_+_28854963 0.08 ENSDART00000153227
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr15_-_945804 0.08 ENSDART00000063257
alox5b.1
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr9_-_28990649 0.08 ENSDART00000078823
ptpn4a
protein tyrosine phosphatase, non-receptor type 4a
chr16_+_14201401 0.08 ENSDART00000113679
dap3
death associated protein 3
chr16_-_383664 0.07 ENSDART00000051693
irx4a
iroquois homeobox 4a
chr15_+_37546391 0.07 ENSDART00000186625
psenen
presenilin enhancer gamma secretase subunit
chr23_+_3721042 0.07 ENSDART00000143323
smim29
small integral membrane protein 29
chr7_-_40657831 0.07 ENSDART00000084153
nom1
nucleolar protein with MIF4G domain 1
chr5_-_41841892 0.06 ENSDART00000167089
si:dkey-65b12.6
si:dkey-65b12.6
chr2_-_51275873 0.06 ENSDART00000168019
si:ch211-215e19.4
si:ch211-215e19.4
chr4_-_5538752 0.06 ENSDART00000180219
BX324164.5

chr7_-_59515569 0.06 ENSDART00000163343
ENSDART00000165457
ENSDART00000163745
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr17_+_4408809 0.06 ENSDART00000113401
si:zfos-364h11.1
si:zfos-364h11.1
chr7_-_29356084 0.05 ENSDART00000075757
gtf2a2
general transcription factor IIA, 2
chr25_+_19008497 0.05 ENSDART00000104420
samm50
SAMM50 sorting and assembly machinery component
chr18_+_33284202 0.05 ENSDART00000132758
v2ra17
vomeronasal 2 receptor, a17
chr21_+_18405585 0.04 ENSDART00000139318
si:dkey-1d7.3
si:dkey-1d7.3
chr12_+_19030391 0.04 ENSDART00000153927
si:ch73-139e5.2
si:ch73-139e5.2
chr22_-_5171362 0.04 ENSDART00000124889
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr8_+_23745167 0.03 ENSDART00000149352
si:ch211-163l21.11
si:ch211-163l21.11
chr25_-_37180969 0.03 ENSDART00000152338
tdrd12
tudor domain containing 12
chr5_+_41477954 0.02 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr20_+_4222357 0.01 ENSDART00000188331
ipcef1
interaction protein for cytohesin exchange factors 1
chr22_+_2315996 0.01 ENSDART00000132489
znf1175
zinc finger protein 1175
chr9_+_53637932 0.01 ENSDART00000188962
CABZ01084081.1

chr15_-_15910226 0.00 ENSDART00000154219
synrg
synergin, gamma
chr2_-_38312757 0.00 ENSDART00000167274
ap1g2
adaptor-related protein complex 1, gamma 2 subunit
chr4_+_20085114 0.00 ENSDART00000186698
ENSDART00000188635
ppp6r2a
protein phosphatase 6, regulatory subunit 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of six3a+six3b+six7_six1a+six2a+six2b+six5+six9_six1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0010039 response to iron ion(GO:0010039)
0.3 1.0 GO:0019417 sulfur oxidation(GO:0019417)
0.2 1.0 GO:0070166 enamel mineralization(GO:0070166)
0.2 1.0 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 1.3 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.1 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.6 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.5 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.8 GO:0006032 chitin catabolic process(GO:0006032)
0.1 1.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.1 GO:0071712 protein O-linked mannosylation(GO:0035269) ER-associated misfolded protein catabolic process(GO:0071712)
0.1 3.0 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.1 0.3 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.6 GO:0009651 response to salt stress(GO:0009651)
0.0 1.5 GO:0035304 regulation of protein dephosphorylation(GO:0035304)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0030320 microglia differentiation(GO:0014004) cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.4 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.0 0.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.4 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.0 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.3 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 1.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0003994 aconitate hydratase activity(GO:0003994)
0.6 3.0 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.4 1.5 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.4 1.1 GO:0004771 sterol esterase activity(GO:0004771)
0.4 1.8 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.2 1.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0015562 inositol hexakisphosphate binding(GO:0000822) efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.1 GO:0008061 chitin binding(GO:0008061)
0.1 1.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.6 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 1.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 2.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 1.3 GO:0032934 sterol binding(GO:0032934)
0.0 1.0 GO:0071949 FAD binding(GO:0071949)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 4.9 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases