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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sox18

Z-value: 0.60

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Transcription factors associated with sox18

Gene Symbol Gene ID Gene Info
sox18
ENSDARG00000058598 SRY-box transcription factor 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox18dr11_v1_chr23_+_8797143_8797143-0.065.5e-01Click!

Activity profile of sox18 motif

Sorted Z-values of sox18 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_7204378 6.07 ENSDART00000142905
vwf
von Willebrand factor
chr16_+_23403602 5.89 ENSDART00000159848
s100w
S100 calcium binding protein W
chr13_+_25397098 5.13 ENSDART00000132953
gsto2
glutathione S-transferase omega 2
chr13_+_25396896 5.05 ENSDART00000041257
gsto2
glutathione S-transferase omega 2
chr9_+_44832032 5.05 ENSDART00000002633
frzb
frizzled related protein
chr5_-_71722257 4.85 ENSDART00000013404
ak1
adenylate kinase 1
chr8_+_37700090 4.42 ENSDART00000187885
ENSDART00000127633
adrb3a
adrenoceptor beta 3a
chr16_+_23404170 4.42 ENSDART00000170061
s100w
S100 calcium binding protein W
chr16_+_23398369 4.38 ENSDART00000037694
s100a10b
S100 calcium binding protein A10b
chr5_+_39667272 4.25 ENSDART00000085388
bmp3
bone morphogenetic protein 3
chr13_+_25412307 4.18 ENSDART00000175339
calhm1
calcium homeostasis modulator 1
chr11_+_29671661 4.15 ENSDART00000024318
ENSDART00000165024
rnf207a
ring finger protein 207a
chr7_+_22688781 3.67 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr8_+_23726708 3.44 ENSDART00000142395
mkrn4
makorin, ring finger protein, 4
chr24_-_40668208 3.29 ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr24_+_11334733 3.02 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
si:dkey-12l12.1
chr12_-_44122412 3.01 ENSDART00000169094
si:ch73-329n5.3
si:ch73-329n5.3
chr24_+_20372497 3.00 ENSDART00000132340
ENSDART00000139989
ENSDART00000168751
ENSDART00000192909
plcd1a
phospholipase C, delta 1a
chr19_-_31035155 2.95 ENSDART00000161882
bzw2
basic leucine zipper and W2 domains 2
chr16_+_29586468 2.67 ENSDART00000148926
mcl1b
MCL1, BCL2 family apoptosis regulator b
chr12_+_18524953 2.47 ENSDART00000090332
neurl2
neuralized E3 ubiquitin protein ligase 2
chr16_+_29586004 2.45 ENSDART00000149520
mcl1b
MCL1, BCL2 family apoptosis regulator b
chr3_+_25999477 2.18 ENSDART00000024316
mcm5
minichromosome maintenance complex component 5
chr24_+_38658334 2.15 ENSDART00000155735
si:ch73-70c5.1
si:ch73-70c5.1
chr18_-_40905901 2.14 ENSDART00000064848
pglyrp5
peptidoglycan recognition protein 5
chr10_-_42237304 2.12 ENSDART00000140341
tcf7l1a
transcription factor 7 like 1a
chr2_-_27900518 2.09 ENSDART00000109561
ENSDART00000077720
zgc:163121
zgc:163121
chr1_-_49434798 2.01 ENSDART00000150842
ENSDART00000150789
ATP5MD
si:dkeyp-80c12.10
chr5_+_25317061 1.99 ENSDART00000170097
trpm6
transient receptor potential cation channel, subfamily M, member 6
chr22_+_25352530 1.92 ENSDART00000176742
ENSDART00000113186
si:dkey-240e12.6
si:dkey-240e12.6
chr7_+_4922104 1.81 ENSDART00000135154
si:dkey-28d5.11
si:dkey-28d5.11
chr5_-_7829657 1.78 ENSDART00000158374
pdlim5a
PDZ and LIM domain 5a
chr2_-_32262287 1.75 ENSDART00000056621
ENSDART00000039717
fam49ba
family with sequence similarity 49, member Ba
chr1_-_57839070 1.72 ENSDART00000152571
si:dkey-1c7.3
si:dkey-1c7.3
chr7_+_24814866 1.72 ENSDART00000173581
si:ch211-226l4.6
si:ch211-226l4.6
chr20_+_18992679 1.67 ENSDART00000147105
ENSDART00000152811
tdh
L-threonine dehydrogenase
chr6_+_49052741 1.50 ENSDART00000011876
sycp1
synaptonemal complex protein 1
chr17_+_16423721 1.50 ENSDART00000064233
efcab11
EF-hand calcium binding domain 11
chr7_+_22853788 1.47 ENSDART00000148502
clcn5b
chloride channel, voltage-sensitive 5b
chr11_+_17984354 1.46 ENSDART00000179986
rpusd4
RNA pseudouridylate synthase domain containing 4
chr21_+_14511685 1.45 ENSDART00000102099
CR392036.1

chr3_-_31845816 1.42 ENSDART00000157028
map3k3
mitogen-activated protein kinase kinase kinase 3
chr25_+_10416583 1.41 ENSDART00000073907
ehf
ets homologous factor
chr9_+_44994214 1.39 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr11_-_28614608 1.38 ENSDART00000065853
dhrs3b
dehydrogenase/reductase (SDR family) member 3b
chr24_+_9475809 1.38 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1
chr12_-_26407092 1.33 ENSDART00000178687
myoz1b
myozenin 1b
chr5_-_16475374 1.31 ENSDART00000134274
ENSDART00000136004
piwil2
piwi-like RNA-mediated gene silencing 2
chr4_-_13973213 1.30 ENSDART00000067177
ENSDART00000144127
prickle1b
prickle homolog 1b
chr11_+_17984167 1.25 ENSDART00000020283
ENSDART00000188329
rpusd4
RNA pseudouridylate synthase domain containing 4
chr18_+_39649660 1.24 ENSDART00000149859
gldn
gliomedin
chr8_+_14158021 1.23 ENSDART00000080832
si:dkey-6n6.2
si:dkey-6n6.2
chr2_+_3428357 1.21 ENSDART00000125967
CU633991.1

chr10_-_29733194 1.21 ENSDART00000149252
si:ch73-261i21.2
si:ch73-261i21.2
chr19_-_46777963 1.20 ENSDART00000046857
abrab
actin binding Rho activating protein b
chr19_-_3255725 1.14 ENSDART00000105165
illr1
immune-related, lectin-like receptor 1
chr25_+_10987817 1.13 ENSDART00000156529
si:dkey-52p2.5
si:dkey-52p2.5
chr1_+_30551777 1.04 ENSDART00000112778
gpr183b
G protein-coupled receptor 183b
chr17_+_50564070 1.02 ENSDART00000075150
bmp4
bone morphogenetic protein 4
chr3_-_23470986 1.00 ENSDART00000113135
msl1a
male-specific lethal 1 homolog a (Drosophila)
chr21_-_30166097 0.99 ENSDART00000130676
hbegfb
heparin-binding EGF-like growth factor b
chr18_+_39649825 0.91 ENSDART00000087960
gldn
gliomedin
chr6_-_37460178 0.89 ENSDART00000153500
si:dkey-66a8.7
si:dkey-66a8.7
chr5_+_3892551 0.86 ENSDART00000134396
rpain
RPA interacting protein
chr18_-_1270220 0.84 ENSDART00000193754
ugt5f1
UDP glucuronosyltransferase 5 family, polypeptide F1
chr5_+_22459087 0.83 ENSDART00000134781
BX546499.1

chr22_-_8499778 0.82 ENSDART00000142219
si:ch73-27e22.4
si:ch73-27e22.4
chr3_-_34087394 0.81 ENSDART00000151344
ighv4-8
immunoglobulin heavy variable 4-8
chr21_-_5066462 0.81 ENSDART00000067733
zgc:77838
zgc:77838
chr7_+_73807504 0.78 ENSDART00000166244
si:ch73-252p3.1
si:ch73-252p3.1
chr23_+_4373360 0.75 ENSDART00000144061
ptpdc1b
protein tyrosine phosphatase domain containing 1b
chr11_+_5565082 0.74 ENSDART00000112590
ENSDART00000183207
si:ch73-40i7.5
si:ch73-40i7.5
chr16_-_40508624 0.74 ENSDART00000075718
ndufaf6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr24_-_25184553 0.72 ENSDART00000166917
plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr7_+_11390462 0.68 ENSDART00000114383
tlnrd1
talin rod domain containing 1
chr21_+_21012210 0.67 ENSDART00000190317
ndr1
nodal-related 1
chr4_+_30776883 0.66 ENSDART00000169519
si:dkey-11d20.1
si:dkey-11d20.1
chr1_-_2061419 0.64 ENSDART00000058878
oxgr1a.3
oxoglutarate (alpha-ketoglutarate) receptor 1a, tandem duplicate 3
chr2_+_24819790 0.63 ENSDART00000002096
pde4ca
phosphodiesterase 4C, cAMP-specific a
chr3_-_33961589 0.61 ENSDART00000151533
ighd
immunoglobulin heavy constant delta
chr8_-_29677300 0.58 ENSDART00000032407
ENSDART00000143623
prf1.6
perforin 1.6
chr22_-_910926 0.56 ENSDART00000180075
FP016205.1

chr9_+_32306862 0.55 ENSDART00000078513
mob4
MOB family member 4, phocein
chr19_+_15440841 0.54 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr23_-_10831995 0.54 ENSDART00000142533
pdzrn3a
PDZ domain containing RING finger 3a
chr1_-_35924495 0.53 ENSDART00000184424
smad1
SMAD family member 1
chr8_-_17184482 0.52 ENSDART00000025803
pola2
polymerase (DNA directed), alpha 2
chr22_+_9110998 0.50 ENSDART00000141520
nlrp15
NACHT, LRR and PYD domains-containing protein 15
chr25_-_12982193 0.50 ENSDART00000159617
ccl39.5
chemokine (C-C motif) ligand 39, duplicate 5
chr6_+_59029485 0.49 ENSDART00000050140
CABZ01088367.1

chr2_+_32016516 0.49 ENSDART00000135040
mycb
MYC proto-oncogene, bHLH transcription factor b
chr7_+_69459759 0.48 ENSDART00000160500
ctdnep1b
CTD nuclear envelope phosphatase 1b
chr14_-_35400671 0.45 ENSDART00000129676
lsm11
LSM11, U7 small nuclear RNA associated
chr2_-_51593835 0.45 ENSDART00000168072
si:ch211-9d9.7
si:ch211-9d9.7
chr6_-_37459759 0.43 ENSDART00000190666
si:dkey-66a8.7
si:dkey-66a8.7
chr2_+_32016256 0.40 ENSDART00000005143
mycb
MYC proto-oncogene, bHLH transcription factor b
chr5_-_23517747 0.40 ENSDART00000137655
stag2a
stromal antigen 2a
chr3_+_34986837 0.39 ENSDART00000190341
smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr18_-_7400075 0.37 ENSDART00000101250
si:dkey-30c15.13
si:dkey-30c15.13
chr5_+_23994038 0.37 ENSDART00000186175
AL928875.1

chr25_+_35061044 0.37 ENSDART00000111706
si:dkey-108k21.14
si:dkey-108k21.14
chr1_-_11519934 0.35 ENSDART00000162060
sdk1b
sidekick cell adhesion molecule 1b
chr25_-_35104083 0.34 ENSDART00000183252
ENSDART00000156727
si:dkey-108k21.21
si:dkey-108k21.21
chr15_+_11683114 0.33 ENSDART00000168233
si:dkey-31c13.1
si:dkey-31c13.1
chr7_+_73827805 0.29 ENSDART00000109316
zgc:173587
zgc:173587
chr11_-_396724 0.28 ENSDART00000184375
CR855375.3

chr22_+_17118225 0.28 ENSDART00000135604
frem1b
Fras1 related extracellular matrix 1b
chr3_-_34089310 0.27 ENSDART00000151774
ighv5-5
immunoglobulin heavy variable 5-5
chr20_+_37295006 0.25 ENSDART00000153137
cx23
connexin 23
chr8_-_13454281 0.24 ENSDART00000141959
CR354547.2

chr23_+_42482137 0.24 ENSDART00000160199
cyp2aa3
cytochrome P450, family 2, subfamily AA, polypeptide 3
chr5_-_7513082 0.20 ENSDART00000158913
bmpr1ba
bone morphogenetic protein receptor, type IBa
chr8_-_13486258 0.19 ENSDART00000137459
pimr104
Pim proto-oncogene, serine/threonine kinase, related 104
chr19_-_3193912 0.19 ENSDART00000133159
si:ch211-133n4.6
si:ch211-133n4.6
chr7_-_47282853 0.18 ENSDART00000169299
si:ch211-186j3.3
si:ch211-186j3.3
chr20_-_42534153 0.17 ENSDART00000061122
rfx6
regulatory factor X, 6
chr1_+_45707219 0.17 ENSDART00000143363
si:ch211-214c7.4
si:ch211-214c7.4
chr3_+_34159192 0.16 ENSDART00000151119
carm1
coactivator-associated arginine methyltransferase 1
chr22_+_1853999 0.15 ENSDART00000163288
znf1174
zinc finger protein 1174
chr3_+_52145511 0.11 ENSDART00000078485
adgre14
adhesion G protein-coupled receptor E14
chr15_-_31366742 0.10 ENSDART00000125585
or111-3
odorant receptor, family D, subfamily 111, member 3
chr13_-_18863680 0.10 ENSDART00000109277
lzts2a
leucine zipper, putative tumor suppressor 2a
chr4_+_38981587 0.10 ENSDART00000142713
si:dkey-66k12.3
si:dkey-66k12.3
chr10_+_15511885 0.08 ENSDART00000165663
erbin
erbb2 interacting protein
chr14_+_6962271 0.07 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr5_+_61863996 0.07 ENSDART00000082879
sympk
symplekin
chr19_+_43753995 0.05 ENSDART00000058504
SLC17A3
si:ch1073-513e17.1
chr8_-_25600888 0.02 ENSDART00000193860
stk38a
serine/threonine kinase 38a
chr15_+_29728377 0.02 ENSDART00000099958
zgc:153372
zgc:153372
chr15_+_17722054 0.02 ENSDART00000191390
ENSDART00000169550
si:ch211-213d14.1
si:ch211-213d14.1
chr10_+_23441488 0.01 ENSDART00000100783
si:ch73-122g19.1
si:ch73-122g19.1
chr12_-_35105670 0.00 ENSDART00000153034
si:ch73-127m5.2
si:ch73-127m5.2

Network of associatons between targets according to the STRING database.

First level regulatory network of sox18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0035988 chondrocyte proliferation(GO:0035988)
0.9 4.4 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.7 4.8 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.5 2.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.5 1.5 GO:0000711 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.5 3.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.5 2.7 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.3 1.0 GO:0033335 anal fin development(GO:0033335)
0.3 5.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.3 1.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 2.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.2 1.7 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.2 2.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 2.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 4.3 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 1.0 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.3 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.1 1.3 GO:0021535 cell migration in hindbrain(GO:0021535) facial nucleus development(GO:0021754)
0.1 1.4 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.0 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.5 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 6.1 GO:0007596 blood coagulation(GO:0007596)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.7 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 0.2 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.7 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.2 GO:0035775 pronephric glomerulus morphogenesis(GO:0035775)
0.0 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 3.0 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.7 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 1.4 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.6 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.9 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0043073 germ cell nucleus(GO:0043073)
0.3 1.3 GO:1990923 PET complex(GO:1990923)
0.1 1.0 GO:0072487 MSL complex(GO:0072487)
0.1 2.2 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 2.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 10.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 5.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.0 1.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 3.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 24.0 GO:0005615 extracellular space(GO:0005615)
0.0 2.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.3 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0008278 cohesin complex(GO:0008278)
0.0 2.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.2 GO:0030017 sarcomere(GO:0030017)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
1.1 4.4 GO:0051380 norepinephrine binding(GO:0051380)
0.5 2.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.5 14.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 4.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 1.7 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.3 4.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 2.2 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 1.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.3 GO:0034584 piRNA binding(GO:0034584)
0.2 5.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 4.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 1.3 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.8 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 3.0 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 2.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 4.3 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 5.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 6.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 3.3 GO:0003774 motor activity(GO:0003774)
0.0 0.5 GO:0017069 snRNA binding(GO:0017069)
0.0 3.1 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 8.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.7 10.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 4.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling