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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for sox5

Z-value: 1.42

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Transcription factors associated with sox5

Gene Symbol Gene ID Gene Info
ENSDARG00000011582 SRY-box transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox5dr11_v1_chr4_-_17055782_170557820.535.3e-08Click!

Activity profile of sox5 motif

Sorted Z-values of sox5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_21832441 24.27 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
myelin basic protein a
chr5_+_37837245 22.60 ENSDART00000171617
ependymin
chr20_+_34915945 17.45 ENSDART00000153064
synaptosomal-associated protein, 25a
chr16_+_10318893 16.01 ENSDART00000055380
tubulin, beta 5
chr2_+_21855036 14.28 ENSDART00000140012
carbonic anhydrase VIII
chr13_+_7292061 13.34 ENSDART00000179504
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr12_-_3756405 13.19 ENSDART00000150839
family with sequence similarity 57, member Bb
chr10_+_22003750 12.84 ENSDART00000109420
Kv channel interacting protein 1 b
chr3_-_35602233 12.59 ENSDART00000055269
guanine nucleotide binding protein (G protein), gamma 13b
chr23_-_3681026 11.93 ENSDART00000192128
ENSDART00000040086
protein kinase C and casein kinase substrate in neurons 1a
chr13_+_38520927 11.69 ENSDART00000137299
ENSDART00000111080
adhesion G protein-coupled receptor B3
chr15_-_33933790 11.55 ENSDART00000165162
ENSDART00000182258
ENSDART00000183240
myelin associated glycoprotein
chr11_+_39672874 11.48 ENSDART00000046663
ENSDART00000157659
calmodulin binding transcription activator 1b
chr3_-_31804481 11.46 ENSDART00000028270
glial fibrillary acidic protein
chr15_+_28685892 11.02 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr14_-_33872092 10.83 ENSDART00000111903
si:ch73-335m24.2
chr20_-_47704973 10.68 ENSDART00000174808
transcription factor AP-2 beta
chr6_-_21873266 10.58 ENSDART00000151658
ENSDART00000151152
ENSDART00000151179
si:dkey-19e4.5
chr5_-_50748081 10.57 ENSDART00000113985
multiple C2 domains, transmembrane 1a
chr3_-_42086577 10.39 ENSDART00000083111
ENSDART00000187312
tweety family member 3a
chr1_-_38709551 10.38 ENSDART00000128794
glycoprotein M6Ab
chr13_-_22771708 10.30 ENSDART00000112900
si:ch211-150i13.1
chr20_-_35246150 10.26 ENSDART00000090549
frizzled class receptor 3a
chr16_-_43025885 10.15 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr23_+_19590006 9.91 ENSDART00000021231
sarcolemma associated protein b
chr6_+_18520859 9.91 ENSDART00000158263
si:dkey-10p5.10
chr16_-_28856112 9.58 ENSDART00000078543
synaptotagmin XIb
chr7_-_52849913 9.46 ENSDART00000174133
ENSDART00000172951
microtubule-associated protein 1Aa
chr18_-_1185772 9.38 ENSDART00000143245
neuroplastin b
chr3_+_24134418 9.37 ENSDART00000156204
si:ch211-246i5.5
chr7_+_47287307 9.05 ENSDART00000114669
dpy-19 like C-mannosyltransferase 3
chr8_+_31799410 8.91 ENSDART00000141226
3-oxoacid CoA transferase 1a
chr19_+_24872159 8.74 ENSDART00000158490
si:ch211-195b13.1
chr13_+_11440389 8.73 ENSDART00000186463
zinc finger and BTB domain containing 18
chr24_+_24461341 8.56 ENSDART00000147658
basic helix-loop-helix family, member e22
chr5_+_58397646 8.55 ENSDART00000180759
hepatic and glial cell adhesion molecule
chr16_+_23811554 8.37 ENSDART00000114336
si:dkey-7f3.9
chr3_+_29714775 8.35 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr14_-_18671334 8.25 ENSDART00000182381
SLIT and NTRK-like family, member 4
chr24_+_24461558 7.92 ENSDART00000182424
basic helix-loop-helix family, member e22
chr5_-_46273938 7.82 ENSDART00000080033
si:ch211-130m23.3
chr2_+_50626476 7.74 ENSDART00000018150
neuronal differentiation 6b
chr6_+_40587551 7.74 ENSDART00000155554
fibroblast growth factor receptor substrate 3
chr15_+_18863875 7.67 ENSDART00000062603
cell adhesion molecule 1b
chr22_-_26945493 7.52 ENSDART00000077411
chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)
chr25_-_29134654 7.44 ENSDART00000067066
poly (ADP-ribose) polymerase family, member 6b
chr24_-_6647275 7.06 ENSDART00000161494
Rho GTPase activating protein 21a
chr7_-_38861741 7.00 ENSDART00000173629
ENSDART00000037361
ENSDART00000173953
PHD finger protein 21Aa
chr19_+_37848830 6.92 ENSDART00000042276
ENSDART00000180872
neurexophilin 1
chr13_+_28854438 6.80 ENSDART00000193407
ENSDART00000189554

chr19_-_103289 6.80 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr16_-_21047872 6.77 ENSDART00000131582
chromobox homolog 3b
chr24_+_32411753 6.72 ENSDART00000058530
neuronal differentiation 6a
chr10_-_26163989 6.70 ENSDART00000136472
tripartite motif containing 3b
chr13_+_51579851 6.67 ENSDART00000163847
NK6 homeobox 2
chr10_+_23022263 6.67 ENSDART00000138955
si:dkey-175g6.2
chr2_+_56463167 6.47 ENSDART00000123392
RAB11B, member RAS oncogene family, b
chr6_-_38418862 6.33 ENSDART00000104135
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr8_+_23093155 6.30 ENSDART00000063075
zgc:100920
chr8_-_39978767 6.27 ENSDART00000083066
aspartate beta-hydroxylase domain containing 2
chr13_-_20518632 6.26 ENSDART00000165310
gdnf family receptor alpha 1a
chr9_+_32978302 6.25 ENSDART00000007630
nescient helix loop helix 2
chr6_+_39812475 6.12 ENSDART00000067063
complement component 1, q subcomponent-like 4b
chr8_+_31941650 6.02 ENSDART00000138217
5-hydroxytryptamine (serotonin) receptor 1A a
chr8_-_34051548 5.92 ENSDART00000105204
pre-B-cell leukemia homeobox 3b
chr17_-_39185336 5.86 ENSDART00000050534
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr23_-_30787932 5.86 ENSDART00000135771
myelin transcription factor 1a
chr5_-_18446483 5.86 ENSDART00000180027
si:dkey-215k6.1
chr2_+_24867534 5.80 ENSDART00000158050
RAB3A, member RAS oncogene family, a
chr18_-_12327426 5.79 ENSDART00000136992
ENSDART00000114024
family with sequence similarity 107, member B
chr24_-_20658446 5.75 ENSDART00000127923
natural killer cell triggering receptor
chr17_+_33495194 5.75 ENSDART00000033691
parathyroid hormone 2
chr19_-_15335787 5.71 ENSDART00000187131
human immunodeficiency virus type I enhancer binding protein 3a
chr8_-_9118958 5.64 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr19_+_15571290 5.61 ENSDART00000131134
forkhead box O6 b
chr17_+_19626479 5.60 ENSDART00000044993
ENSDART00000131863
regulator of G protein signaling 7a
chr2_-_21170517 5.58 ENSDART00000135417
bmi1 polycomb ring finger oncogene 1b
chr22_-_16443199 5.56 ENSDART00000006290
ENSDART00000193335
pleckstrin homology domain containing, family B (evectins) member 2
chr23_+_30730121 5.54 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr11_+_25010491 5.54 ENSDART00000167285
zgc:92107
chr22_-_20342260 5.52 ENSDART00000161610
ENSDART00000165667
transcription factor 3b
chr11_+_6819050 5.48 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr10_+_21807497 5.46 ENSDART00000164634
protocadherin 1 gamma 32
chr7_+_23515966 5.45 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr1_-_30689004 5.38 ENSDART00000018827
dachshund c
chr17_-_33289304 5.38 ENSDART00000135118
ENSDART00000040346
EFR3 homolog Ba (S. cerevisiae)
chr2_+_31957554 5.37 ENSDART00000012413
ANKH inorganic pyrophosphate transport regulator b
chr17_+_28005763 5.35 ENSDART00000155838
leucine zipper protein 1
chr23_-_36003282 5.31 ENSDART00000103150
calcium binding and coiled-coil domain 1a
chr6_+_42819337 5.27 ENSDART00000046498
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr8_+_25267903 5.23 ENSDART00000093090
adenosine monophosphate deaminase 2b
chr15_-_20949692 5.23 ENSDART00000185548
tubulin folding cofactor E-like a
chr18_-_21267103 5.22 ENSDART00000136285
purine nucleoside phosphorylase 6
chr13_+_12045758 5.15 ENSDART00000079398
ENSDART00000165467
ENSDART00000165880
guanine nucleotide binding protein (G protein), gamma 2
chr1_+_9708801 5.12 ENSDART00000189621
extracellular leucine-rich repeat and fibronectin type III domain containing 1b
chr17_-_14966384 5.09 ENSDART00000105064
thioredoxin domain containing 16
chr16_-_22006996 5.09 ENSDART00000116114
si:dkey-71b5.7
chr9_+_42607138 5.09 ENSDART00000138133
ENSDART00000002027
GULP, engulfment adaptor PTB domain containing 1a
chr20_-_14206698 5.06 ENSDART00000082441
discs, large (Drosophila) homolog-associated protein 2b
chr2_-_36819624 5.04 ENSDART00000140844
SLIT and NTRK-like family, member 3b
chr11_+_16152316 4.92 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr5_+_41793001 4.90 ENSDART00000136439
ENSDART00000190477
ENSDART00000192289
BCL tumor suppressor 7A
chr6_+_11250316 4.89 ENSDART00000137122
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr16_+_5678071 4.80 ENSDART00000011166
ENSDART00000134198
ENSDART00000131575
zgc:158689
chr9_+_31534601 4.72 ENSDART00000133094
si:ch211-168k14.2
chr10_-_28761454 4.63 ENSDART00000129400
activated leukocyte cell adhesion molecule a
chr5_-_28606916 4.62 ENSDART00000026107
ENSDART00000137717
tenascin C
chr19_+_43969363 4.60 ENSDART00000051712
GATA zinc finger domain containing 1
chr14_+_31529958 4.58 ENSDART00000053026
family with sequence similarity 122B
chr15_-_33834577 4.57 ENSDART00000163354
matrix metallopeptidase 13b
chr3_+_54047342 4.56 ENSDART00000178486
olfactomedin 2a
chr3_+_40407352 4.52 ENSDART00000155112
trinucleotide repeat containing 18
chr13_+_12045475 4.50 ENSDART00000163053
ENSDART00000160812
ENSDART00000158244
guanine nucleotide binding protein (G protein), gamma 2
chr20_+_27331008 4.49 ENSDART00000141486
protein phosphatase 4, regulatory subunit 4
chr8_+_13106760 4.44 ENSDART00000029308
integrin, beta 4
chr20_+_54383838 4.39 ENSDART00000157737
leucine rich repeat and fibronectin type III domain containing 5b
chr6_+_12326267 4.36 ENSDART00000155101
si:dkey-276j7.3
chr19_+_7549854 4.31 ENSDART00000138866
ENSDART00000151758
pre-B-cell leukemia homeobox interacting protein 1a
chr1_-_22726233 4.19 ENSDART00000140920
prominin 1 b
chr10_+_33744098 4.15 ENSDART00000147775
relaxin/insulin-like family peptide receptor 2a
chr13_-_20519001 4.13 ENSDART00000168955
gdnf family receptor alpha 1a
chr17_-_21418340 4.12 ENSDART00000007021
ATPase, H+ transporting, lysosomal, V1 subunit B, member a
chr17_-_24564674 4.03 ENSDART00000105435
ENSDART00000135086
ATP-binding cassette, sub-family H, member 1
chr5_-_32158198 4.01 ENSDART00000187215
ENSDART00000137503
IL-6 subfamily cytokine M17
chr13_+_29773153 3.99 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
paired box 2a
chr18_+_38900092 3.96 ENSDART00000148541
ENSDART00000133618
ENSDART00000088037
myosin VAa
chr6_+_54358529 3.92 ENSDART00000153704
ankyrin repeat and sterile alpha motif domain containing 1Ab
chr16_+_27614989 3.90 ENSDART00000005625
GLI pathogenesis-related 2, like
chr16_+_19033554 3.90 ENSDART00000182430
Rap guanine nucleotide exchange factor (GEF) 5b
chr4_-_19016396 3.90 ENSDART00000166160
si:dkey-31f5.11
chr11_+_21587950 3.90 ENSDART00000162251
zgc:101564
chr5_-_38342992 3.88 ENSDART00000140337
misshapen-like kinase 1
chr7_-_18601206 3.86 ENSDART00000111636
si:ch211-119e14.2
chr7_+_25003851 3.85 ENSDART00000144526
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr23_+_20523617 3.85 ENSDART00000176404
activity-dependent neuroprotector homeobox b
chr5_+_20147830 3.84 ENSDART00000098727
SV2 related protein a
chr6_+_42818963 3.83 ENSDART00000184833
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr7_+_30970045 3.83 ENSDART00000155974
tight junction protein 1a
chr16_-_21047483 3.81 ENSDART00000136235
chromobox homolog 3b
chr24_+_26039464 3.77 ENSDART00000131017
tyrosine kinase, non-receptor, 2a
chr21_-_25573064 3.75 ENSDART00000134310

chr14_+_49683767 3.72 ENSDART00000192515
tetraspanin 17
chr9_-_33749556 3.72 ENSDART00000149383
Norrie disease (pseudoglioma)
chr19_+_1964005 3.72 ENSDART00000172049
SH3-domain binding protein 5a (BTK-associated)
chr10_+_15255012 3.72 ENSDART00000023766
very low density lipoprotein receptor
chr2_+_16696052 3.70 ENSDART00000022356
ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr1_+_45958904 3.69 ENSDART00000108528
Rho guanine nucleotide exchange factor (GEF) 7b
chr18_+_19131773 3.65 ENSDART00000060766
RAB11a, member RAS oncogene family
chr10_+_15255198 3.63 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr23_-_33944597 3.61 ENSDART00000133223
si:dkey-190g6.2
chr4_-_8902406 3.61 ENSDART00000192962
metallophosphoesterase domain containing 1
chr21_-_27201495 3.55 ENSDART00000145013
zgc:77262
chr22_+_18530395 3.54 ENSDART00000105415
ENSDART00000183958
si:ch211-212d10.1
chr5_-_40910749 3.50 ENSDART00000083467
ENSDART00000133183
poly (ADP-ribose) polymerase family, member 8
chr13_+_3667230 3.50 ENSDART00000131553
ENSDART00000189841
ENSDART00000183554
ENSDART00000018737
QKI, KH domain containing, RNA binding b
chr13_+_3938526 3.50 ENSDART00000012759
Yip1 domain family, member 3
chr11_+_37612214 3.46 ENSDART00000172899
ENSDART00000077496
heterochromatin protein 1, binding protein 3
chr11_+_16153207 3.45 ENSDART00000192356
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr9_-_27649406 3.40 ENSDART00000181270
ENSDART00000187112
syntaxin binding protein 5-like
chr3_+_52999962 3.40 ENSDART00000104683
pre-B-cell leukemia transcription factor 4
chr20_-_31238313 3.40 ENSDART00000028471
hippocalcin-like 1
chr6_-_28943056 3.39 ENSDART00000065138
TBC1 domain family, member 23
chr19_-_45960191 3.33 ENSDART00000052434
ENSDART00000172732
eukaryotic translation initiation factor 3, subunit H, b
chr15_+_31471808 3.32 ENSDART00000110078
odorant receptor, family C, subfamily 102, member 3
chr11_+_37612672 3.30 ENSDART00000157993
heterochromatin protein 1, binding protein 3
chr24_+_17069420 3.28 ENSDART00000014787
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr21_+_37357578 3.27 ENSDART00000143621
nuclear receptor binding SET domain protein 1b
chr22_-_29906764 3.25 ENSDART00000019786
structural maintenance of chromosomes 3
chr2_+_38556195 3.24 ENSDART00000138769
cadherin 24, type 2b
chr7_-_31938938 3.22 ENSDART00000132353
brain-derived neurotrophic factor
chr25_-_29134000 3.20 ENSDART00000172027
ENSDART00000190447
poly (ADP-ribose) polymerase family, member 6b
chr14_-_2217285 3.19 ENSDART00000157949
ENSDART00000166150
ENSDART00000054891
ENSDART00000183268
protocadherin 2 alpha b2
protocadherin 2 alpha b2
chr19_+_20793388 3.14 ENSDART00000142463
thioredoxin-like 4A
chr23_-_30727596 3.12 ENSDART00000060193
THAP domain containing, apoptosis associated protein 3
chr4_-_16412084 3.10 ENSDART00000188460
decorin
chr21_-_2707768 3.10 ENSDART00000165384

chr14_-_30808174 3.10 ENSDART00000173262
protease, serine, 23
chr9_+_38163876 3.09 ENSDART00000137955
cytoplasmic linker associated protein 1a
chr6_-_12900154 3.09 ENSDART00000080408
ENSDART00000150887
islet cell autoantigen 1-like
chr25_+_388258 3.08 ENSDART00000166834
regulatory factor X7b
chr19_-_38872650 3.07 ENSDART00000146641
adhesion G protein-coupled receptor B2
chr15_-_21669618 3.06 ENSDART00000156995
sortilin-related receptor, L(DLR class) A repeats containing
chr21_+_10782013 3.04 ENSDART00000146248
zinc finger protein 532
chr5_-_67911111 3.03 ENSDART00000051833
GS homeobox 1
chr15_+_29728377 3.03 ENSDART00000099958
zgc:153372
chr5_+_17624463 3.02 ENSDART00000183869
ENSDART00000081064
fibrosin-like 1
chr23_-_36446307 2.98 ENSDART00000136623
zgc:174906
chr15_+_5028608 2.92 ENSDART00000092809
ATP-binding cassette, sub-family G (WHITE), member 1
chr20_+_38837238 2.91 ENSDART00000061334
intraflagellar transport 172
chr2_-_36818132 2.89 ENSDART00000110447
SLIT and NTRK-like family, member 3b
chr13_+_13770980 2.87 ENSDART00000113089
solute carrier family 4, sodium borate transporter, member 11
chr17_+_23968214 2.86 ENSDART00000183053
exportin 1 (CRM1 homolog, yeast) b
chr17_-_35278763 2.83 ENSDART00000063437
ADAM metallopeptidase domain 17a
chr6_+_9163007 2.81 ENSDART00000183054
ENSDART00000157552
zgc:112023
chr6_+_32382743 2.81 ENSDART00000190009
dedicator of cytokinesis 7
chr9_+_35860975 2.79 ENSDART00000134447
regulator of calcineurin 1a
chr2_-_48966431 2.73 ENSDART00000147948
potassium inwardly-rectifying channel, subfamily J, member 9
chr15_-_14467394 2.71 ENSDART00000191944
numb homolog (Drosophila)-like
chr20_+_26943072 2.69 ENSDART00000153215
cell division cycle associated 4
chr14_-_24761132 2.68 ENSDART00000146299
slit homolog 3 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of sox5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
3.0 9.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
2.3 11.7 GO:0016322 neuron remodeling(GO:0016322)
1.9 7.5 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
1.8 8.9 GO:0046952 ketone body catabolic process(GO:0046952)
1.7 6.8 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
1.5 4.6 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
1.2 3.7 GO:0071896 protein localization to adherens junction(GO:0071896)
1.1 12.6 GO:0050909 sensory perception of taste(GO:0050909)
1.1 3.4 GO:1990403 embryonic brain development(GO:1990403)
1.0 13.5 GO:0021754 facial nucleus development(GO:0021754)
0.8 6.6 GO:0021588 cerebellum formation(GO:0021588)
0.8 2.4 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.7 2.9 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.7 2.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.7 7.7 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.6 5.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.6 2.5 GO:0071548 cellular response to cortisol stimulus(GO:0071387) response to dexamethasone(GO:0071548)
0.6 4.3 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.6 17.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.6 3.4 GO:0003232 bulbus arteriosus development(GO:0003232)
0.6 4.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.6 11.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.5 11.9 GO:0097320 membrane tubulation(GO:0097320)
0.5 3.7 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.5 1.6 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.5 1.6 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.5 2.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.5 8.3 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.5 4.9 GO:0044805 late nucleophagy(GO:0044805)
0.5 2.4 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.5 5.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.4 3.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.4 1.3 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.4 6.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4 2.0 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.4 6.8 GO:0070828 heterochromatin organization(GO:0070828)
0.4 2.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.4 5.2 GO:0032264 IMP salvage(GO:0032264)
0.4 14.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.4 1.5 GO:0015840 urea transport(GO:0015840)
0.4 9.5 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.4 1.8 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.3 3.8 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 12.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 2.0 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.3 3.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 4.1 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.3 2.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 3.1 GO:0003160 endocardium morphogenesis(GO:0003160)
0.3 3.7 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 19.9 GO:0021549 cerebellum development(GO:0021549)
0.3 8.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.3 3.9 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.3 5.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.3 3.7 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.3 8.4 GO:0043967 histone H4 acetylation(GO:0043967)
0.3 12.8 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.3 6.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.3 6.0 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.3 12.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.3 3.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 9.7 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.2 32.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.2 4.0 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.2 5.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 6.0 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.2 1.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 2.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 1.4 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.2 13.7 GO:0050919 negative chemotaxis(GO:0050919)
0.2 1.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 3.6 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 2.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 5.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 2.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 4.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 6.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.2 3.5 GO:0048570 notochord morphogenesis(GO:0048570)
0.2 17.0 GO:0031101 fin regeneration(GO:0031101)
0.2 2.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.2 5.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.4 GO:2000047 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.2 15.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.2 5.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.2 0.8 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.1 4.0 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.1 4.6 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 4.4 GO:0001763 morphogenesis of a branching structure(GO:0001763)
0.1 3.1 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 4.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 2.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.7 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 4.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.1 3.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 2.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 6.8 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 1.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 7.2 GO:0045055 regulated exocytosis(GO:0045055)
0.1 1.2 GO:0007525 somatic muscle development(GO:0007525)
0.1 2.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 7.3 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 1.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 5.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.1 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 3.5 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 1.9 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.9 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 3.4 GO:0017157 regulation of exocytosis(GO:0017157)
0.1 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 14.0 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 4.0 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 1.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.9 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 2.6 GO:0061512 protein localization to cilium(GO:0061512)
0.1 1.4 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.5 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 5.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 5.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 2.7 GO:1990573 potassium ion import(GO:0010107) potassium ion import across plasma membrane(GO:1990573)
0.1 1.8 GO:0030901 midbrain development(GO:0030901)
0.0 3.4 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 8.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 5.0 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 3.7 GO:0006821 chloride transport(GO:0006821)
0.0 0.9 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 1.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 6.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.8 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.4 GO:0099565 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 1.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.6 GO:0045010 actin nucleation(GO:0045010)
0.0 1.9 GO:0016573 histone acetylation(GO:0016573)
0.0 0.9 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 1.1 GO:0036269 swimming behavior(GO:0036269)
0.0 1.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 2.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.4 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 3.4 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 17.8 GO:0030182 neuron differentiation(GO:0030182)
0.0 0.6 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 2.2 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.1 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.4 GO:0051169 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.2 GO:0098781 ncRNA transcription(GO:0098781)
0.0 0.1 GO:0097324 adult behavior(GO:0030534) melanocyte migration(GO:0097324)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 17.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.9 11.7 GO:0043083 synaptic cleft(GO:0043083)
1.6 28.6 GO:0043209 myelin sheath(GO:0043209)
1.3 4.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.0 3.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.9 8.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.9 10.4 GO:0044295 axonal growth cone(GO:0044295)
0.8 5.5 GO:0035517 PR-DUB complex(GO:0035517)
0.7 3.4 GO:0071203 WASH complex(GO:0071203)
0.6 3.7 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.6 9.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.5 7.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.5 1.6 GO:0042382 paraspeckles(GO:0042382)
0.5 4.2 GO:0071914 prominosome(GO:0071914)
0.5 2.0 GO:0097524 sperm plasma membrane(GO:0097524)
0.4 2.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 6.2 GO:0031209 SCAR complex(GO:0031209)
0.3 2.4 GO:0033010 paranodal junction(GO:0033010)
0.3 3.3 GO:0042788 polysomal ribosome(GO:0042788)
0.3 3.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.3 12.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 16.7 GO:0034707 chloride channel complex(GO:0034707)
0.2 4.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 1.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 9.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 8.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 2.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 4.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 1.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.5 GO:0031213 RSF complex(GO:0031213)
0.2 3.8 GO:0005771 multivesicular body(GO:0005771)
0.2 2.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 36.0 GO:0070382 exocytic vesicle(GO:0070382)
0.1 2.5 GO:0005682 U5 snRNP(GO:0005682)
0.1 2.2 GO:0043195 terminal bouton(GO:0043195)
0.1 5.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 7.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 11.5 GO:0005882 intermediate filament(GO:0005882)
0.1 1.9 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 8.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 4.4 GO:0008305 integrin complex(GO:0008305)
0.1 9.5 GO:0043025 neuronal cell body(GO:0043025)
0.1 6.5 GO:0055037 recycling endosome(GO:0055037)
0.1 13.6 GO:0030424 axon(GO:0030424)
0.1 1.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 6.8 GO:0000786 nucleosome(GO:0000786)
0.1 4.5 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 3.2 GO:0016342 catenin complex(GO:0016342)
0.1 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 6.7 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 4.6 GO:0031674 I band(GO:0031674)
0.0 0.8 GO:0030175 filopodium(GO:0030175)
0.0 1.9 GO:0031201 SNARE complex(GO:0031201)
0.0 2.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 10.4 GO:0005768 endosome(GO:0005768)
0.0 1.3 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 10.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.3 GO:0030496 midbody(GO:0030496)
0.0 7.6 GO:0005764 lysosome(GO:0005764)
0.0 2.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 4.2 GO:0000785 chromatin(GO:0000785)
0.0 1.8 GO:0030027 lamellipodium(GO:0030027)
0.0 3.6 GO:0036477 dendrite(GO:0030425) somatodendritic compartment(GO:0036477)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 3.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 7.0 GO:0005874 microtubule(GO:0005874)
0.0 0.9 GO:0005930 axoneme(GO:0005930)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 20.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.6 GO:0005929 cilium(GO:0005929)
0.0 2.3 GO:0045202 synapse(GO:0045202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.8 8.9 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
1.6 24.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.5 10.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.3 7.7 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
1.2 10.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.1 5.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.1 5.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
1.0 22.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.0 3.9 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.8 3.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.7 5.2 GO:0004630 phospholipase D activity(GO:0004630)
0.7 2.1 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.7 6.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.6 2.6 GO:0008384 IkappaB kinase activity(GO:0008384)
0.6 11.6 GO:0033691 sialic acid binding(GO:0033691)
0.6 9.1 GO:0038191 neuropilin binding(GO:0038191)
0.6 5.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.5 14.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 5.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 1.4 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.5 2.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5 10.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.5 7.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 6.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.4 17.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 5.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.4 2.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 3.6 GO:0048039 ubiquinone binding(GO:0048039)
0.4 5.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 5.7 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.4 7.5 GO:0042056 chemoattractant activity(GO:0042056)
0.3 3.1 GO:0043515 kinetochore binding(GO:0043515)
0.3 2.0 GO:0008126 acetylesterase activity(GO:0008126)
0.3 2.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 9.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 2.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 16.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 14.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 8.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.3 1.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 6.0 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 3.2 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.2 1.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 3.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 4.2 GO:0070122 isopeptidase activity(GO:0070122)
0.2 5.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 2.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 3.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 5.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 3.4 GO:0045159 myosin II binding(GO:0045159)
0.2 9.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 8.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 2.7 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 6.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 6.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 1.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 1.6 GO:0005522 profilin binding(GO:0005522)
0.1 3.1 GO:0005518 collagen binding(GO:0005518)
0.1 3.7 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 1.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 2.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 9.2 GO:0016247 channel regulator activity(GO:0016247)
0.1 2.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 6.8 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.9 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 2.9 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 3.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 4.4 GO:0005178 integrin binding(GO:0005178)
0.1 7.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 26.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 4.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 1.7 GO:0019213 deacetylase activity(GO:0019213)
0.1 2.1 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 2.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.2 GO:0019905 syntaxin binding(GO:0019905)
0.1 8.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 21.8 GO:0003924 GTPase activity(GO:0003924)
0.1 1.3 GO:0017069 snRNA binding(GO:0017069)
0.1 5.0 GO:0045296 cadherin binding(GO:0045296)
0.1 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 4.6 GO:0042802 identical protein binding(GO:0042802)
0.1 1.0 GO:0048185 activin binding(GO:0048185)
0.0 4.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 25.5 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 16.5 GO:0005543 phospholipid binding(GO:0005543)
0.0 10.6 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 10.9 GO:0008017 microtubule binding(GO:0008017)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 29.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 4.0 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 0.1 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 1.9 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 8.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.7 GO:0003724 RNA helicase activity(GO:0003724)
0.0 5.4 GO:0003682 chromatin binding(GO:0003682)
0.0 4.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 1.2 GO:0046332 SMAD binding(GO:0046332)
0.0 0.3 GO:0005496 steroid binding(GO:0005496)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 1.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.3 GO:0060090 binding, bridging(GO:0060090)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 3.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 7.3 PID REELIN PATHWAY Reelin signaling pathway
0.3 4.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 1.4 PID IGF1 PATHWAY IGF1 pathway
0.2 3.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 7.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 14.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 1.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 8.2 PID SHP2 PATHWAY SHP2 signaling
0.2 2.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 4.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.9 PID ATM PATHWAY ATM pathway
0.1 2.7 PID FGF PATHWAY FGF signaling pathway
0.1 2.3 PID BMP PATHWAY BMP receptor signaling
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.5 1.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.4 0.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.4 6.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.4 9.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 2.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 7.7 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.3 2.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 1.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 2.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 3.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 5.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 1.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 5.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 1.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 3.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 3.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 6.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 3.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 3.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis