ISMARA results: tbr1b_tbx16+tbx16l+tbx2a+tbx2b

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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for tbr1b_tbx16+tbx16l+tbx2a+tbx2b

Z-value: 1.14

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Transcription factors associated with tbr1b_tbx16+tbx16l+tbx2a+tbx2b

Gene Symbol	Gene ID	Gene Info
tbr1b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000004712	T-box brain transcription factor 1b
tbx2b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000006120	T-box transcription factor 2b
tbx16l NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000006939	T-box transcription factor 16, like
tbx16 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000007329	T-box transcription factor 16
tbx2a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000018025	T-box transcription factor 2a
tbx2a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000109541	T-box transcription factor 2a
tbx2b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000116135	T-box transcription factor 2b

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
tbx16	dr11_v1_chr8_-_51753604_51753604	-0.77	1.6e-19	Click!
tbr1b	dr11_v1_chr9_-_51436377_51436377	-0.69	2.0e-14	Click!
tbx6l	dr11_v1_chr5_+_42280372_42280372	-0.25	1.4e-02	Click!
tbx2a	dr11_v1_chr5_-_56513825_56513825	0.15	1.5e-01	Click!
tbx2b	dr11_v1_chr15_+_27364394_27364394	0.08	4.2e-01	Click!

Activity profile of tbr1b_tbx16+tbx16l+tbx2a+tbx2b motif

Sorted Z-values of tbr1b_tbx16+tbx16l+tbx2a+tbx2b motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr13_-_51846224 Show fit	28.15	ENSDART00000184663	LT631684.2 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr7_+_7048245 Show fit	15.40	ENSDART00000001649	actn3b NCBI UniProt ZFIN ENSEMBL Google Show fit	actinin alpha 3b
chr7_+_6969909 Show fit	12.59	ENSDART00000189886	actn3b NCBI UniProt ZFIN ENSEMBL Google Show fit	actinin alpha 3b
chr17_+_26965351 Show fit	11.42	ENSDART00000114215 ENSDART00000147192	grhl3 NCBI UniProt ZFIN ENSEMBL Google Show fit	grainyhead-like transcription factor 3
chr7_+_69841017 Show fit	11.22	ENSDART00000169107	FO818704.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr9_-_42873700 Show fit	10.73	ENSDART00000125953	ttn.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	titin, tandem duplicate 1
chr3_+_32526263 Show fit	10.62	ENSDART00000150897	si:ch73-367p23.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-367p23.2
chr19_+_791538 Show fit	9.72	ENSDART00000146554 ENSDART00000138406	tmem79a NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 79a
chr23_+_23232136 Show fit	9.11	ENSDART00000126479 ENSDART00000187764	plekhn1 NCBI UniProt ZFIN ENSEMBL Google Show fit	pleckstrin homology domain containing, family N member 1
chr13_-_15702672 Show fit	8.63	ENSDART00000144445 ENSDART00000168950	ckba NCBI UniProt ZFIN ENSEMBL Google Show fit	creatine kinase, brain a
chr14_+_21106444 Show fit	8.61	ENSDART00000075744 ENSDART00000132363	aldob NCBI UniProt ZFIN ENSEMBL Google Show fit	aldolase b, fructose-bisphosphate
chr11_-_25257045 Show fit	8.58	ENSDART00000130477	snai1a NCBI UniProt ZFIN ENSEMBL Google Show fit	snail family zinc finger 1a
chr6_+_56141852 Show fit	7.95	ENSDART00000149665	tfap2c NCBI UniProt ZFIN ENSEMBL Google Show fit	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr23_-_20100436 Show fit	7.93	ENSDART00000143445	si:dkey-32e6.6 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-32e6.6
chr3_-_61181018 Show fit	7.90	ENSDART00000187970	pvalb4 NCBI UniProt ZFIN ENSEMBL Google Show fit	parvalbumin 4
chr21_-_22928214 Show fit	7.83	ENSDART00000182760	dub NCBI UniProt ZFIN ENSEMBL Google Show fit	duboraya
chr3_-_32603191 Show fit	7.79	ENSDART00000150997	si:ch73-248e21.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-248e21.7
chr7_+_39446247 Show fit	7.73	ENSDART00000033610 ENSDART00000099015	tnnt3b NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin T type 3b (skeletal, fast)
chr15_+_32711663 Show fit	7.73	ENSDART00000157854 ENSDART00000167515	postnb NCBI UniProt ZFIN ENSEMBL Google Show fit	periostin, osteoblast specific factor b
chr18_-_7539166 Show fit	7.62	ENSDART00000133541	si:dkey-30c15.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-30c15.2
chr2_+_36007449 Show fit	7.51	ENSDART00000161837	lamc2 NCBI UniProt ZFIN ENSEMBL Google Show fit	laminin, gamma 2
chr22_+_661711 Show fit	7.36	ENSDART00000113795	elf3 NCBI UniProt ZFIN ENSEMBL Google Show fit	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr11_-_25257595 Show fit	7.35	ENSDART00000123567	snai1a NCBI UniProt ZFIN ENSEMBL Google Show fit	snail family zinc finger 1a
chr12_+_6002715 Show fit	7.31	ENSDART00000114961	si:ch211-131k2.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-131k2.3
chr1_-_49521407 Show fit	7.28	ENSDART00000189845 ENSDART00000143474	zp3c NCBI UniProt ZFIN ENSEMBL Google Show fit	zona pellucida glycoprotein 3c
chr18_+_29156827 Show fit	7.23	ENSDART00000137587 ENSDART00000135633	ppfibp2a NCBI UniProt ZFIN ENSEMBL Google Show fit	PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr22_+_26600834 Show fit	7.10	ENSDART00000157411	adcy9 NCBI UniProt ZFIN ENSEMBL Google Show fit	adenylate cyclase 9
chr5_+_43006422 Show fit	7.03	ENSDART00000009182	aqp3a NCBI UniProt ZFIN ENSEMBL Google Show fit	aquaporin 3a
chr7_+_38750871 Show fit	6.98	ENSDART00000114238 ENSDART00000052325 ENSDART00000137001	f2 NCBI UniProt ZFIN ENSEMBL Google Show fit	coagulation factor II (thrombin)
chr7_-_52417777 Show fit	6.93	ENSDART00000110265	myzap NCBI UniProt ZFIN ENSEMBL Google Show fit	myocardial zonula adherens protein
chr25_-_27819838 Show fit	6.84	ENSDART00000067106	lmod2a NCBI UniProt ZFIN ENSEMBL Google Show fit	leiomodin 2 (cardiac) a
chr13_+_33606739 Show fit	6.72	ENSDART00000026464	cfl1l NCBI UniProt ZFIN ENSEMBL Google Show fit	cofilin 1 (non-muscle), like
chr9_-_443451 Show fit	6.70	ENSDART00000165642	si:dkey-11f4.14 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-11f4.14
chr19_+_30990815 Show fit	6.66	ENSDART00000134645	sync NCBI UniProt ZFIN ENSEMBL Google Show fit	syncoilin, intermediate filament protein
chr19_-_7420867 Show fit	6.58	ENSDART00000081741	rab25a NCBI UniProt ZFIN ENSEMBL Google Show fit	RAB25, member RAS oncogene family a
chr19_+_7735157 Show fit	6.42	ENSDART00000186717	tuft1b NCBI UniProt ZFIN ENSEMBL Google Show fit	tuftelin 1b
chr21_-_11575626 Show fit	6.15	ENSDART00000133171	cast NCBI UniProt ZFIN ENSEMBL Google Show fit	calpastatin
chr7_+_3357973 Show fit	6.13	ENSDART00000172853	si:ch211-285c6.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-285c6.5
chr10_-_1961930 Show fit	6.08	ENSDART00000122446	tdgf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	teratocarcinoma-derived growth factor 1
chr12_-_10567188 Show fit	5.87	ENSDART00000144283	myof NCBI UniProt ZFIN ENSEMBL Google Show fit	myoferlin
chr24_+_35975398 Show fit	5.72	ENSDART00000173058	obscnb NCBI UniProt ZFIN ENSEMBL Google Show fit	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr15_+_32711172 Show fit	5.63	ENSDART00000163936 ENSDART00000168135	postnb NCBI UniProt ZFIN ENSEMBL Google Show fit	periostin, osteoblast specific factor b
chr7_+_65240227 Show fit	5.61	ENSDART00000168287	bco1l NCBI UniProt ZFIN ENSEMBL Google Show fit	beta-carotene oxygenase 1, like
chr14_+_17376940 Show fit	5.53	ENSDART00000054590 ENSDART00000010148	spon2b NCBI UniProt ZFIN ENSEMBL Google Show fit	spondin 2b, extracellular matrix protein
chr14_+_48862987 Show fit	5.51	ENSDART00000167810	zgc:154054 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:154054
chr20_-_26846028 Show fit	5.48	ENSDART00000136687	mylk4b NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin light chain kinase family, member 4b
chr10_+_43994471 Show fit	5.42	ENSDART00000138242 ENSDART00000186359	cldn5b NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin 5b
chr18_+_7591381 Show fit	5.42	ENSDART00000136313	si:dkeyp-1h4.6 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-1h4.6
chr22_+_25693295 Show fit	5.39	ENSDART00000123888 ENSDART00000150783	si:dkeyp-98a7.4 NCBI UniProt ZFIN ENSEMBL Google Show fit si:dkeyp-98a7.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-98a7.4 si:dkeyp-98a7.3
chr5_-_25037454 Show fit	5.38	ENSDART00000027237	abo NCBI UniProt ZFIN ENSEMBL Google Show fit	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr23_+_9867483 Show fit	5.33	ENSDART00000023099	slc16a7 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr22_+_25704430 Show fit	5.32	ENSDART00000143776	si:dkeyp-98a7.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-98a7.3
chr22_-_24757785 Show fit	5.30	ENSDART00000078225	vtg5 NCBI UniProt ZFIN ENSEMBL Google Show fit	vitellogenin 5
chr8_+_39663612 Show fit	5.29	ENSDART00000188074	BX005328.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr2_-_30182353 Show fit	5.25	ENSDART00000019149	rpl7 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L7
chr22_+_25681911 Show fit	5.23	ENSDART00000113381	si:dkeyp-98a7.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-98a7.3
chr19_+_2590182 Show fit	5.22	ENSDART00000162293	si:ch73-345f18.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-345f18.3
chr7_-_19614916 Show fit	5.15	ENSDART00000169029	zgc:194655 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:194655
chr22_+_25715925 Show fit	5.13	ENSDART00000150650	si:dkeyp-98a7.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-98a7.7
chr17_-_8907668 Show fit	4.97	ENSDART00000155996 ENSDART00000155624	nkl.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	NK-lysin tandem duplicate 1
chr8_-_24252933 Show fit	4.97	ENSDART00000057624	zgc:110353 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:110353
chr22_+_25687525 Show fit	4.95	ENSDART00000135717	si:dkeyp-98a7.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-98a7.3
chr13_+_31757331 Show fit	4.94	ENSDART00000044282	hif1aa NCBI UniProt ZFIN ENSEMBL Google Show fit	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a
chr7_-_53117131 Show fit	4.94	ENSDART00000169211 ENSDART00000168890 ENSDART00000172179 ENSDART00000167882	cdh1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cadherin 1, type 1, E-cadherin (epithelial)
chr25_+_4960509 Show fit	4.93	ENSDART00000155984	si:ch73-265h17.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-265h17.4
chr11_+_6650966 Show fit	4.92	ENSDART00000131236	si:dkey-246j7.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-246j7.1
chr10_+_3127809 Show fit	4.92	ENSDART00000185500	ckmt2a NCBI UniProt ZFIN ENSEMBL Google Show fit	creatine kinase, mitochondrial 2a (sarcomeric)
chr13_+_18533005 Show fit	4.85	ENSDART00000136024	ftr14l NCBI UniProt ZFIN ENSEMBL Google Show fit	finTRIM family, member 14-like
chr19_+_9305964 Show fit	4.83	ENSDART00000136241	si:ch73-15n24.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-15n24.1
chr21_+_10866421 Show fit	4.81	ENSDART00000137858	alpk2 NCBI UniProt ZFIN ENSEMBL Google Show fit	alpha-kinase 2
chr13_-_9442942 Show fit	4.78	ENSDART00000138833	grxcr1 NCBI UniProt ZFIN ENSEMBL Google Show fit	glutaredoxin, cysteine rich 1
chr8_-_11229523 Show fit	4.76	ENSDART00000002164	unc45b NCBI UniProt ZFIN ENSEMBL Google Show fit	unc-45 myosin chaperone B
chr3_+_43086548 Show fit	4.72	ENSDART00000163579	si:dkey-43p13.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-43p13.5
chr5_+_27525477 Show fit	4.70	ENSDART00000051491	sfrp1a NCBI UniProt ZFIN ENSEMBL Google Show fit	secreted frizzled-related protein 1a
chr24_-_27419198 Show fit	4.63	ENSDART00000141124	ccl34b.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	chemokine (C-C motif) ligand 34b, duplicate 4
chr6_-_46941245 Show fit	4.60	ENSDART00000037875	igfn1.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 1
chr24_-_34680956 Show fit	4.58	ENSDART00000171009	ctnna1 NCBI UniProt ZFIN ENSEMBL Google Show fit	catenin (cadherin-associated protein), alpha 1
chr11_+_37178271 Show fit	4.56	ENSDART00000161771	itih3b NCBI UniProt ZFIN ENSEMBL Google Show fit	inter-alpha-trypsin inhibitor heavy chain 3b
chr12_+_10062953 Show fit	4.47	ENSDART00000148689	slc4a1b NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 4 (anion exchanger), member 1b (Diego blood group)
chr22_+_25710148 Show fit	4.42	ENSDART00000150446	si:dkeyp-98a7.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-98a7.4
chr10_-_32524035 Show fit	4.40	ENSDART00000137608	dgat2 NCBI UniProt ZFIN ENSEMBL Google Show fit	diacylglycerol O-acyltransferase 2
chr2_-_42234484 Show fit	4.40	ENSDART00000132617 ENSDART00000136690 ENSDART00000141358	apom NCBI UniProt ZFIN ENSEMBL Google Show fit	apolipoprotein M
chr23_-_29003864 Show fit	4.38	ENSDART00000148257	casz1 NCBI UniProt ZFIN ENSEMBL Google Show fit	castor zinc finger 1
chr9_-_40011673 Show fit	4.37	ENSDART00000184726	IKZF2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:zfos-1425h8.1
chr17_+_51517750 Show fit	4.37	ENSDART00000180896 ENSDART00000193528	pxdn NCBI UniProt ZFIN ENSEMBL Google Show fit	peroxidasin
chr4_-_11580948 Show fit	4.35	ENSDART00000049066	net1 NCBI UniProt ZFIN ENSEMBL Google Show fit	neuroepithelial cell transforming 1
chr16_-_32233463 Show fit	4.35	ENSDART00000102016	calhm6 NCBI UniProt ZFIN ENSEMBL Google Show fit	calcium homeostasis modulator family member 6
chr7_-_58776400 Show fit	4.33	ENSDART00000167433	sox17 NCBI UniProt ZFIN ENSEMBL Google Show fit	SRY (sex determining region Y)-box 17
chr5_-_4204580 Show fit	4.32	ENSDART00000049197 ENSDART00000132130	si:ch211-283g2.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-283g2.1
chr5_-_44843738 Show fit	4.31	ENSDART00000003926	fbp1a NCBI UniProt ZFIN ENSEMBL Google Show fit	fructose-1,6-bisphosphatase 1a
chr25_+_36292057 Show fit	4.30	ENSDART00000152329	bmb NCBI UniProt ZFIN ENSEMBL Google Show fit	brambleberry
chr19_+_917852 Show fit	4.27	ENSDART00000082466	tgfbr2a NCBI UniProt ZFIN ENSEMBL Google Show fit	transforming growth factor beta receptor 2a
chr22_+_25720725 Show fit	4.24	ENSDART00000150778	si:dkeyp-98a7.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-98a7.8
chr21_-_34951265 Show fit	4.24	ENSDART00000135222	lipia NCBI UniProt ZFIN ENSEMBL Google Show fit	lipase, member Ia
chr15_-_5580093 Show fit	4.24	ENSDART00000143726	wdr62 NCBI UniProt ZFIN ENSEMBL Google Show fit	WD repeat domain 62
chr22_+_1123110 Show fit	4.22	ENSDART00000171017	si:ch1073-181h11.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-181h11.2
chr1_-_6028876 Show fit	4.22	ENSDART00000168117	si:ch1073-345a8.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-345a8.1
chr24_-_36593876 Show fit	4.18	ENSDART00000160901	CABZ01055365.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr18_-_48550426 Show fit	4.17	ENSDART00000145189	kcnj1a.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr9_-_21970067 Show fit	4.16	ENSDART00000009920	lmo7a NCBI UniProt ZFIN ENSEMBL Google Show fit	LIM domain 7a
chr5_-_38170996 Show fit	4.10	ENSDART00000145805	si:ch211-284e13.12 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-284e13.12
chr13_-_51922290 Show fit	4.04	ENSDART00000168648	srfb NCBI UniProt ZFIN ENSEMBL Google Show fit	serum response factor b
chr13_-_41908583 Show fit	4.03	ENSDART00000136515	ipmka NCBI UniProt ZFIN ENSEMBL Google Show fit	inositol polyphosphate multikinase a
chr7_+_65673885 Show fit	3.99	ENSDART00000169182	parvab NCBI UniProt ZFIN ENSEMBL Google Show fit	parvin, alpha b
chr1_+_8521323 Show fit	3.98	ENSDART00000121439 ENSDART00000103626 ENSDART00000141283	mief2 NCBI UniProt ZFIN ENSEMBL Google Show fit	mitochondrial elongation factor 2
chr16_+_13993285 Show fit	3.98	ENSDART00000139130 ENSDART00000130353	si:dkey-85k15.7 NCBI UniProt ZFIN ENSEMBL Google Show fit fdps NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-85k15.7 farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr21_+_5531138 Show fit	3.97	ENSDART00000163825	ly6m6 NCBI UniProt ZFIN ENSEMBL Google Show fit	lymphocyte antigen 6 family member M6
chr2_+_45081489 Show fit	3.96	ENSDART00000123966	chrng NCBI UniProt ZFIN ENSEMBL Google Show fit	cholinergic receptor, nicotinic, gamma
chr21_+_28445052 Show fit	3.95	ENSDART00000077871	pygma NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphorylase, glycogen, muscle A
chr12_-_14143344 Show fit	3.94	ENSDART00000152742	buc2l NCBI UniProt ZFIN ENSEMBL Google Show fit	bucky ball 2-like
chr13_+_1799003 Show fit	3.93	ENSDART00000029343	col21a1 NCBI UniProt ZFIN ENSEMBL Google Show fit	collagen, type XXI, alpha 1
chr5_-_32505109 Show fit	3.91	ENSDART00000188219	ntmt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr10_+_33171501 Show fit	3.90	ENSDART00000159666	myl10 NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin, light chain 10, regulatory
chr16_+_29492937 Show fit	3.90	ENSDART00000011497	ctsk NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin K
chr16_-_12723738 Show fit	3.89	ENSDART00000080414	sbk3 NCBI UniProt ZFIN ENSEMBL Google Show fit	SH3 domain binding kinase family, member 3
chr7_+_2797795 Show fit	3.86	ENSDART00000161208	si:ch211-217i17.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-217i17.1
chr1_+_51615672 Show fit	3.85	ENSDART00000165117	zgc:165656 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:165656
chr5_-_42878178 Show fit	3.85	ENSDART00000162981	CXCL11 (1 of many) NCBI UniProt ZFIN ENSEMBL Google Show fit	C-X-C motif chemokine ligand 11
chr18_+_8340886 Show fit	3.85	ENSDART00000081132	cpt1b NCBI UniProt ZFIN ENSEMBL Google Show fit	carnitine palmitoyltransferase 1B (muscle)
chr8_+_36142734 Show fit	3.84	ENSDART00000159361 ENSDART00000161194	mhc2b NCBI UniProt ZFIN ENSEMBL Google Show fit	major histocompatibility complex class II integral membrane beta chain gene
chr24_-_18919562 Show fit	3.83	ENSDART00000144244 ENSDART00000106188 ENSDART00000182518	cpa6 NCBI UniProt ZFIN ENSEMBL Google Show fit	carboxypeptidase A6
chr14_+_97017 Show fit	3.83	ENSDART00000159300 ENSDART00000169523	mcm7 NCBI UniProt ZFIN ENSEMBL Google Show fit	minichromosome maintenance complex component 7
chr6_+_36877968 Show fit	3.81	ENSDART00000155187	traf3ip2l NCBI UniProt ZFIN ENSEMBL Google Show fit	TRAF3 interacting protein 2-like
chr22_-_35330532 Show fit	3.78	ENSDART00000172654	FO818743.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr10_-_25816558 Show fit	3.77	ENSDART00000017240	postna NCBI UniProt ZFIN ENSEMBL Google Show fit	periostin, osteoblast specific factor a
chr9_+_8851819 Show fit	3.69	ENSDART00000160004	col4a2 NCBI UniProt ZFIN ENSEMBL Google Show fit	collagen, type IV, alpha 2
chr17_+_34186632 Show fit	3.68	ENSDART00000014306	mpp5a NCBI UniProt ZFIN ENSEMBL Google Show fit	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr24_-_26369185 Show fit	3.65	ENSDART00000080039	lrrc31 NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine rich repeat containing 31
chr7_+_13988075 Show fit	3.65	ENSDART00000186812	furina NCBI UniProt ZFIN ENSEMBL Google Show fit	furin (paired basic amino acid cleaving enzyme) a
chr15_-_43164591 Show fit	3.64	ENSDART00000171305	ap1s3a NCBI UniProt ZFIN ENSEMBL Google Show fit	adaptor-related protein complex 1, sigma 3 subunit, a
chr12_+_13244149 Show fit	3.62	ENSDART00000186984 ENSDART00000105896	atp2a1l NCBI UniProt ZFIN ENSEMBL Google Show fit	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr19_-_34999379 Show fit	3.60	ENSDART00000051751	zgc:113424 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:113424
chr6_+_36839509 Show fit	3.60	ENSDART00000190605 ENSDART00000104160	zgc:110788 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:110788
chr22_+_25734180 Show fit	3.59	ENSDART00000143367	si:dkeyp-98a7.9 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-98a7.9
chr13_-_25767210 Show fit	3.58	ENSDART00000131792	pdlim1 NCBI UniProt ZFIN ENSEMBL Google Show fit	PDZ and LIM domain 1 (elfin)
chr17_-_5583345 Show fit	3.57	ENSDART00000035944	clic5a NCBI UniProt ZFIN ENSEMBL Google Show fit	chloride intracellular channel 5a
chr15_-_47848544 Show fit	3.57	ENSDART00000098711	eif3k NCBI UniProt ZFIN ENSEMBL Google Show fit	eukaryotic translation initiation factor 3, subunit K
chr18_+_54354 Show fit	3.50	ENSDART00000097163	zgc:158482 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:158482
chr7_-_5070794 Show fit	3.48	ENSDART00000097877	ltb4r2a NCBI UniProt ZFIN ENSEMBL Google Show fit	leukotriene B4 receptor 2a
chr19_-_5332784 Show fit	3.48	ENSDART00000010373	krt1-19d NCBI UniProt ZFIN ENSEMBL Google Show fit	keratin, type 1, gene 19d
chr22_-_9649627 Show fit	3.46	ENSDART00000164721	si:dkey-286j17.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-286j17.4
chr3_-_23643751 Show fit	3.46	ENSDART00000078425 ENSDART00000140264	eve1 NCBI UniProt ZFIN ENSEMBL Google Show fit	even-skipped-like1
chr5_-_68022631 Show fit	3.44	ENSDART00000143199	wasf3a NCBI UniProt ZFIN ENSEMBL Google Show fit	WAS protein family, member 3a
chr22_-_17652112 Show fit	3.42	ENSDART00000189205	hmha1b NCBI UniProt ZFIN ENSEMBL Google Show fit	histocompatibility (minor) HA-1 b
chr16_-_20312146 Show fit	3.41	ENSDART00000134980	si:dkeyp-86h10.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-86h10.3
chr16_-_54455573 Show fit	3.41	ENSDART00000075275	pklr NCBI UniProt ZFIN ENSEMBL Google Show fit	pyruvate kinase L/R
chr21_-_3700334 Show fit	3.41	ENSDART00000137844	atp8b1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ATPase phospholipid transporting 8B1
chr3_-_39171968 Show fit	3.39	ENSDART00000154494	si:dkeyp-57f11.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-57f11.2
chr8_-_25327809 Show fit	3.39	ENSDART00000137242	eps8l3b NCBI UniProt ZFIN ENSEMBL Google Show fit	EPS8-like 3b
chr10_+_38610741 Show fit	3.38	ENSDART00000126444	mmp13a NCBI UniProt ZFIN ENSEMBL Google Show fit	matrix metallopeptidase 13a
chr17_+_38255105 Show fit	3.38	ENSDART00000005296	nkx2.9 NCBI UniProt ZFIN ENSEMBL Google Show fit	NK2 transcription factor related, locus 9 (Drosophila)
chr10_-_13116337 Show fit	3.37	ENSDART00000164568	musk NCBI UniProt ZFIN ENSEMBL Google Show fit	muscle, skeletal, receptor tyrosine kinase
chr15_-_1590858 Show fit	3.37	ENSDART00000081875	nnr NCBI UniProt ZFIN ENSEMBL Google Show fit	nanor
chr11_+_27274355 Show fit	3.36	ENSDART00000113707	fbln2 NCBI UniProt ZFIN ENSEMBL Google Show fit	fibulin 2
chr3_+_32526799 Show fit	3.36	ENSDART00000185755	si:ch73-367p23.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-367p23.2
chr16_+_38201840 Show fit	3.35	ENSDART00000044971	myo1eb NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin IE, b
chr13_-_27354003 Show fit	3.33	ENSDART00000101479 ENSDART00000044652	ddx43 NCBI UniProt ZFIN ENSEMBL Google Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr19_-_20270178 Show fit	3.32	ENSDART00000144891 ENSDART00000090883	gpnmb NCBI UniProt ZFIN ENSEMBL Google Show fit	glycoprotein (transmembrane) nmb
chr2_+_38161318 Show fit	3.31	ENSDART00000044264	mmp14b NCBI UniProt ZFIN ENSEMBL Google Show fit	matrix metallopeptidase 14b (membrane-inserted)
chr7_-_38638809 Show fit	3.31	ENSDART00000144341	c6ast4 NCBI UniProt ZFIN ENSEMBL Google Show fit	six-cysteine containing astacin protease 4
chr10_+_38417512 Show fit	3.31	ENSDART00000112457	samsn1b NCBI UniProt ZFIN ENSEMBL Google Show fit	SAM domain, SH3 domain and nuclear localisation signals 1b
chr4_+_14981854 Show fit	3.30	ENSDART00000067046	cax1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cation/H+ exchanger protein 1
chr20_+_15600167 Show fit	3.25	ENSDART00000171991	faslg NCBI UniProt ZFIN ENSEMBL Google Show fit	Fas ligand (TNF superfamily, member 6)
chr2_-_58257624 Show fit	3.25	ENSDART00000098940	foxl2b NCBI UniProt ZFIN ENSEMBL Google Show fit	forkhead box L2b
chr6_+_41039166 Show fit	3.23	ENSDART00000125659	entpd8 NCBI UniProt ZFIN ENSEMBL Google Show fit	ectonucleoside triphosphate diphosphohydrolase 8
chr10_-_11376491 Show fit	3.22	ENSDART00000145346	plac8.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	placenta-specific 8, tandem duplicate 2
chr16_+_21790870 Show fit	3.21	ENSDART00000155039	trim108 NCBI UniProt ZFIN ENSEMBL Google Show fit	tripartite motif containing 108
chr6_-_46861676 Show fit	3.21	ENSDART00000188712 ENSDART00000190148	igfn1.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr20_-_33961697 Show fit	3.19	ENSDART00000061765	selp NCBI UniProt ZFIN ENSEMBL Google Show fit	selectin P
chr15_+_7054754 Show fit	3.16	ENSDART00000149800	foxl2a NCBI UniProt ZFIN ENSEMBL Google Show fit	forkhead box L2a
chr11_-_7380674 Show fit	3.16	ENSDART00000014979 ENSDART00000103418	vtg3 NCBI UniProt ZFIN ENSEMBL Google Show fit	vitellogenin 3, phosvitinless
chr5_+_33498253 Show fit	3.16	ENSDART00000140993	ms4a17c.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	membrane-spanning 4-domains, subfamily A, member 17c.2
chr2_+_2470687 Show fit	3.15	ENSDART00000184024 ENSDART00000061955	myl13 NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin, light chain 13
chr10_+_252425 Show fit	3.14	ENSDART00000059478	lrrc32 NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine rich repeat containing 32
chr21_+_21374277 Show fit	3.14	ENSDART00000079431	rtn2b NCBI UniProt ZFIN ENSEMBL Google Show fit	reticulon 2b
chr10_-_1961576 Show fit	3.13	ENSDART00000042441	tdgf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	teratocarcinoma-derived growth factor 1
chr16_+_29516098 Show fit	3.12	ENSDART00000174895	ctss2.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin S, ortholog 2, tandem duplicate 2
chr5_-_69180587 Show fit	3.09	ENSDART00000156681 ENSDART00000160753	zgc:171967 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:171967
chr20_-_51946052 Show fit	3.09	ENSDART00000074325	dusp10 NCBI UniProt ZFIN ENSEMBL Google Show fit	dual specificity phosphatase 10
chr17_-_8312923 Show fit	3.09	ENSDART00000064678	lft2 NCBI UniProt ZFIN ENSEMBL Google Show fit	lefty2
chr16_+_23978978 Show fit	3.08	ENSDART00000058964 ENSDART00000135084	apoa2 NCBI UniProt ZFIN ENSEMBL Google Show fit	apolipoprotein A-II
chr8_+_50531709 Show fit	3.07	ENSDART00000193352	PEBP4 NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphatidylethanolamine binding protein 4
chr18_+_27300700 Show fit	3.07	ENSDART00000140444	plekha7a NCBI UniProt ZFIN ENSEMBL Google Show fit	pleckstrin homology domain containing, family A member 7a
chr7_+_15329819 Show fit	3.07	ENSDART00000006018	mespaa NCBI UniProt ZFIN ENSEMBL Google Show fit	mesoderm posterior aa
chr22_+_15315655 Show fit	3.06	ENSDART00000141249	sult3st3 NCBI UniProt ZFIN ENSEMBL Google Show fit	sulfotransferase family 3, cytosolic sulfotransferase 3
chr5_-_28016805 Show fit	3.05	ENSDART00000078642	vps37b NCBI UniProt ZFIN ENSEMBL Google Show fit	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr24_+_35564668 Show fit	3.04	ENSDART00000122734	cebpd NCBI UniProt ZFIN ENSEMBL Google Show fit	CCAAT/enhancer binding protein (C/EBP), delta
chr7_+_15313443 Show fit	3.04	ENSDART00000045385	mespba NCBI UniProt ZFIN ENSEMBL Google Show fit	mesoderm posterior ba
chr23_-_16734009 Show fit	3.03	ENSDART00000125449	si:ch211-224l10.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-224l10.4
chr11_+_21050326 Show fit	3.02	ENSDART00000065984	zgc:113307 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:113307
chr25_+_3507368 Show fit	3.01	ENSDART00000157777	zgc:153293 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:153293
chr24_-_40700596 Show fit	3.01	ENSDART00000162635	smyhc2 NCBI UniProt ZFIN ENSEMBL Google Show fit	slow myosin heavy chain 2
chr6_-_26895314 Show fit	2.98	ENSDART00000134259	hdlbpa NCBI UniProt ZFIN ENSEMBL Google Show fit	high density lipoprotein binding protein a
chr3_+_47245764 Show fit	2.97	ENSDART00000193581	tnfsf14 NCBI UniProt ZFIN ENSEMBL Google Show fit	TNF superfamily member 14
chr9_+_8380728 Show fit	2.97	ENSDART00000133501	si:ch1073-75o15.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-75o15.4
chr11_+_37251825 Show fit	2.96	ENSDART00000169804	il17rc NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin 17 receptor C
chr5_-_16475682 Show fit	2.96	ENSDART00000090695	piwil2 NCBI UniProt ZFIN ENSEMBL Google Show fit	piwi-like RNA-mediated gene silencing 2
chr9_-_7390388 Show fit	2.94	ENSDART00000132392	slc23a3 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 23, member 3
chr5_+_61843752 Show fit	2.94	ENSDART00000130940	CR759879.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	Danio rerio interferon-induced protein with tetratricopeptide repeats 5 (LOC572297), mRNA.
chr7_+_25221757 Show fit	2.93	ENSDART00000173551	exoc6b NCBI UniProt ZFIN ENSEMBL Google Show fit	exocyst complex component 6B

Network of associatons between targets according to the STRING database.

First level regulatory network of tbr1b_tbx16+tbx16l+tbx2a+tbx2b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	9.2	GO:0090008	hypoblast development(GO:0090008)
2.6	7.8	GO:0061341	non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
2.4	7.2	GO:0005986	sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
2.3	9.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
2.2	6.7	GO:0030043	actin filament fragmentation(GO:0030043)
2.1	6.4	GO:0048496	maintenance of organ identity(GO:0048496)
1.6	4.9	GO:0090134	mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
1.5	1.5	GO:0060063	Spemann organizer formation at the embryonic shield(GO:0060063)
1.4	8.5	GO:0097101	blood vessel endothelial cell fate specification(GO:0097101)
1.3	4.0	GO:0052576	carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
1.3	5.3	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
1.3	3.9	GO:0006480	N-terminal protein amino acid methylation(GO:0006480)
1.3	8.8	GO:0006953	acute-phase response(GO:0006953)
1.3	3.8	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
1.1	4.4	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
1.0	13.5	GO:0006603	phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
1.0	3.1	GO:0045218	zonula adherens maintenance(GO:0045218)
1.0	4.9	GO:0000741	karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.9	2.8	GO:0045649	regulation of macrophage differentiation(GO:0045649)
0.9	2.8	GO:1902103	meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.9	19.6	GO:0008078	mesodermal cell migration(GO:0008078)
0.9	6.1	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.8	15.1	GO:0016203	muscle attachment(GO:0016203)
0.8	6.8	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.7	11.1	GO:0060325	face morphogenesis(GO:0060325)
0.7	2.2	GO:0032640	tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.7	2.8	GO:0055021	regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.7	2.8	GO:0014743	regulation of muscle hypertrophy(GO:0014743)
0.7	2.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.7	2.7	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.7	10.7	GO:0048769	sarcomerogenesis(GO:0048769)
0.7	4.0	GO:0045337	farnesyl diphosphate biosynthetic process(GO:0045337)
0.7	2.0	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.6	2.6	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.6	1.9	GO:0005997	xylulose metabolic process(GO:0005997)
0.6	3.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.6	1.2	GO:0070199	establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.6	8.0	GO:0014034	neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.6	1.2	GO:0048322	axial mesoderm formation(GO:0048320) axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327)
0.6	9.0	GO:0048382	mesendoderm development(GO:0048382)
0.6	5.4	GO:0016121	carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.6	2.4	GO:0061033	lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.6	3.4	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.6	2.8	GO:0010692	regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.5	2.2	GO:0002532	production of molecular mediator involved in inflammatory response(GO:0002532)
0.5	8.0	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.5	9.0	GO:0035803	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.5	3.2	GO:0097241	hematopoietic stem cell migration to bone marrow(GO:0097241)
0.5	1.6	GO:0046689	response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.5	3.7	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.5	2.1	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.5	5.5	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5	2.0	GO:0034087	establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.5	1.5	GO:0060584	regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5	1.9	GO:0060829	negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.5	1.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.5	1.4	GO:1901004	ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.5	3.6	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.5	4.1	GO:1900407	regulation of cellular response to oxidative stress(GO:1900407)
0.4	1.3	GO:1902571	regulation of serine-type peptidase activity(GO:1902571)
0.4	2.7	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.4	2.1	GO:2001293	malonyl-CoA metabolic process(GO:2001293)
0.4	1.3	GO:0001783	B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.4	3.4	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.4	1.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.4	1.6	GO:0003413	plasma membrane repair(GO:0001778) chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.4	2.0	GO:0048730	epidermis morphogenesis(GO:0048730)
0.4	3.2	GO:0031179	peptide modification(GO:0031179)
0.4	2.4	GO:0033986	response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.4	8.2	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.4	6.9	GO:0009437	carnitine metabolic process(GO:0009437)
0.4	1.5	GO:0051876	pigment granule dispersal(GO:0051876)
0.4	1.5	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.4	1.1	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.4	1.1	GO:1904983	transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.4	1.1	GO:0032369	negative regulation of lipid transport(GO:0032369)
0.4	2.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.4	2.5	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4	4.2	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
0.3	3.8	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3	0.7	GO:0002676	granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.3	6.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3	2.4	GO:0045901	positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.3	2.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3	1.3	GO:0070317	G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.3	1.3	GO:0035988	chondrocyte proliferation(GO:0035988)
0.3	2.6	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.3	1.0	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.3	5.4	GO:0030259	lipid glycosylation(GO:0030259)
0.3	0.9	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.3	1.6	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.3	9.4	GO:0032355	response to estradiol(GO:0032355)
0.3	0.9	GO:1903961	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.3	5.1	GO:0019433	triglyceride catabolic process(GO:0019433)
0.3	2.0	GO:0006741	NADP biosynthetic process(GO:0006741)
0.3	1.4	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.3	2.9	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.3	1.1	GO:0015878	biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3	1.4	GO:0071305	cellular response to vitamin D(GO:0071305)
0.3	3.1	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661)
0.3	2.4	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3	1.9	GO:0097535	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.3	1.3	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.3	2.6	GO:0086003	cardiac muscle cell contraction(GO:0086003)
0.3	1.8	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3	1.3	GO:0007584	response to nutrient(GO:0007584)
0.3	6.3	GO:0071456	cellular response to hypoxia(GO:0071456)
0.3	1.8	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3	1.0	GO:0016038	absorption of visible light(GO:0016038)
0.2	10.2	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.2	3.4	GO:0032264	IMP salvage(GO:0032264)
0.2	2.2	GO:0035372	protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2	2.7	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2	1.2	GO:0070445	regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2	3.1	GO:0003128	heart field specification(GO:0003128)
0.2	5.9	GO:0007520	myoblast fusion(GO:0007520)
0.2	0.9	GO:1990511	piRNA biosynthetic process(GO:1990511)
0.2	2.5	GO:0072698	protein localization to microtubule cytoskeleton(GO:0072698)
0.2	3.4	GO:0051127	positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2	0.7	GO:0007060	male meiosis chromosome segregation(GO:0007060)
0.2	2.1	GO:0021794	thalamus development(GO:0021794)
0.2	3.2	GO:1900077	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.2	2.3	GO:0044030	regulation of DNA methylation(GO:0044030)
0.2	0.9	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.2	1.1	GO:0007525	somatic muscle development(GO:0007525)
0.2	7.9	GO:0043113	receptor clustering(GO:0043113)
0.2	11.5	GO:0099515	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.2	1.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.2	1.5	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.2	1.5	GO:0003262	endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.2	0.6	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.2	1.5	GO:0046292	formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.2	2.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.2	0.8	GO:0051645	Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.2	0.6	GO:0098725	somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.2	1.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.2	1.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.2	0.6	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.2	1.2	GO:0032367	intracellular cholesterol transport(GO:0032367)
0.2	1.2	GO:0072695	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2	4.5	GO:0048246	macrophage chemotaxis(GO:0048246)
0.2	1.2	GO:0071800	podosome assembly(GO:0071800)
0.2	3.1	GO:0055013	cardiac muscle cell development(GO:0055013)
0.2	21.4	GO:0030239	myofibril assembly(GO:0030239)
0.2	1.3	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.2	3.2	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2	1.8	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2	1.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2	0.5	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.2	0.5	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2	0.7	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2	3.5	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.2	4.4	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.2	3.1	GO:0030168	platelet activation(GO:0030168)
0.2	0.7	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.2	1.0	GO:0050994	regulation of lipid catabolic process(GO:0050994)
0.2	4.6	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.2	0.3	GO:0030238	female sex determination(GO:0030237) male sex determination(GO:0030238)
0.2	1.3	GO:0071459	protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.2	2.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.2	2.0	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.2	0.3	GO:0072679	thymocyte migration(GO:0072679)
0.2	7.1	GO:0070830	apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2	1.0	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2	3.5	GO:0048570	notochord morphogenesis(GO:0048570)
0.2	1.3	GO:0051673	membrane disruption in other organism(GO:0051673)
0.2	0.9	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.2	0.8	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.2	1.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2	0.6	GO:0051012	microtubule sliding(GO:0051012)
0.2	2.4	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.2	3.0	GO:0043171	peptide catabolic process(GO:0043171)
0.1	5.2	GO:0002377	immunoglobulin production(GO:0002377)
0.1	0.7	GO:0071265	L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1	0.6	GO:0042304	regulation of fatty acid biosynthetic process(GO:0042304)
0.1	4.1	GO:0051923	sulfation(GO:0051923)
0.1	1.6	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1	1.3	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	1.7	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.1	1.6	GO:0035587	adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	2.8	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	7.3	GO:0035567	non-canonical Wnt signaling pathway(GO:0035567)
0.1	2.1	GO:0042407	cristae formation(GO:0042407)
0.1	1.9	GO:0032098	regulation of appetite(GO:0032098)
0.1	2.9	GO:0032438	melanosome organization(GO:0032438)
0.1	1.4	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	0.8	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1	0.8	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.9	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.1	2.3	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.9	GO:0033628	regulation of cell adhesion mediated by integrin(GO:0033628)
0.1	0.5	GO:0007220	Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1	0.1	GO:2000257	regulation of protein activation cascade(GO:2000257)
0.1	3.7	GO:0019882	antigen processing and presentation(GO:0019882)
0.1	0.7	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.1	1.6	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.6	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.1	0.7	GO:0060832	oocyte animal/vegetal axis specification(GO:0060832)
0.1	1.3	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.1	0.6	GO:0045581	CD4-positive, alpha-beta T cell differentiation involved in immune response(GO:0002294) T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) T-helper cell differentiation(GO:0042093) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) negative regulation of T cell differentiation(GO:0045581) negative regulation of lymphocyte differentiation(GO:0045620) regulation of T-helper cell differentiation(GO:0045622) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of alpha-beta T cell differentiation(GO:0046639) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329) positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1	1.3	GO:0003207	cardiac chamber formation(GO:0003207)
0.1	1.0	GO:0050909	sensory perception of taste(GO:0050909)
0.1	1.2	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	3.1	GO:0006749	glutathione metabolic process(GO:0006749)
0.1	0.3	GO:0003222	ventricular trabecula myocardium morphogenesis(GO:0003222)
0.1	1.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	1.5	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	0.9	GO:0002761	regulation of myeloid leukocyte differentiation(GO:0002761)
0.1	1.3	GO:0030048	actin filament-based movement(GO:0030048)
0.1	1.2	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.1	5.7	GO:0030318	melanocyte differentiation(GO:0030318)
0.1	2.1	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	2.7	GO:0051014	actin filament severing(GO:0051014)
0.1	3.1	GO:0003094	glomerular filtration(GO:0003094)
0.1	1.5	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	2.8	GO:0016925	protein sumoylation(GO:0016925)
0.1	2.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.9	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1	2.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.1	0.4	GO:0006529	asparagine biosynthetic process(GO:0006529)
0.1	0.4	GO:0048901	anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1	0.6	GO:0021535	cell migration in hindbrain(GO:0021535)
0.1	3.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	1.3	GO:0006570	tyrosine metabolic process(GO:0006570)
0.1	0.5	GO:0001955	blood vessel maturation(GO:0001955)
0.1	3.7	GO:0003009	skeletal muscle contraction(GO:0003009)
0.1	0.6	GO:0035627	ceramide transport(GO:0035627)
0.1	2.8	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	1.1	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	1.1	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.1	2.1	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1	3.6	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.1	4.1	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.1	4.5	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1	0.9	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.1	1.7	GO:0015914	phospholipid transport(GO:0015914)
0.1	4.0	GO:0048821	erythrocyte development(GO:0048821)
0.1	1.9	GO:0090148	membrane fission(GO:0090148)
0.1	2.9	GO:0045332	phospholipid translocation(GO:0045332)
0.1	1.9	GO:0015701	bicarbonate transport(GO:0015701)
0.1	1.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.1	2.9	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
0.1	1.2	GO:0005979	regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1	1.4	GO:0006939	smooth muscle contraction(GO:0006939)
0.1	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.7	GO:0038203	TORC2 signaling(GO:0038203)
0.1	6.5	GO:0031101	fin regeneration(GO:0031101)
0.1	5.6	GO:0015718	monocarboxylic acid transport(GO:0015718)
0.1	3.6	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	3.6	GO:0017144	drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1	1.0	GO:0006119	oxidative phosphorylation(GO:0006119)
0.1	11.0	GO:0042157	lipoprotein metabolic process(GO:0042157)
0.1	3.4	GO:0009410	response to xenobiotic stimulus(GO:0009410)
0.1	1.2	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.1	0.9	GO:0043248	proteasome assembly(GO:0043248)
0.1	0.9	GO:0044154	histone H3-K14 acetylation(GO:0044154)
0.1	0.3	GO:0061088	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1	0.9	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1	0.6	GO:0009303	rRNA transcription(GO:0009303)
0.1	3.6	GO:0032869	cellular response to insulin stimulus(GO:0032869)
0.1	1.5	GO:0042113	B cell activation(GO:0042113)
0.1	4.6	GO:0060215	primitive hemopoiesis(GO:0060215)
0.1	4.6	GO:0001894	tissue homeostasis(GO:0001894)
0.1	13.6	GO:0009617	response to bacterium(GO:0009617)
0.1	2.3	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.1	0.9	GO:0071545	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1	2.5	GO:0051262	protein tetramerization(GO:0051262)
0.1	1.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	0.7	GO:0048922	posterior lateral line neuromast deposition(GO:0048922)
0.1	2.3	GO:0002062	chondrocyte differentiation(GO:0002062)
0.1	1.3	GO:0048546	digestive tract morphogenesis(GO:0048546)
0.1	0.4	GO:0000272	polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1	0.6	GO:0002695	negative regulation of leukocyte activation(GO:0002695) negative regulation of cell activation(GO:0050866) negative regulation of lymphocyte activation(GO:0051250)
0.1	0.9	GO:0019835	cytolysis(GO:0019835)
0.1	1.4	GO:0006826	iron ion transport(GO:0006826)
0.1	0.6	GO:0018120	peptidyl-arginine ADP-ribosylation(GO:0018120)
0.1	3.6	GO:0006006	glucose metabolic process(GO:0006006)
0.1	2.9	GO:0022904	respiratory electron transport chain(GO:0022904)
0.1	1.5	GO:0044243	collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1	0.8	GO:0002574	thrombocyte differentiation(GO:0002574)
0.1	2.8	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.6	GO:0043651	lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1	0.4	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1	1.6	GO:0051904	melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1	0.3	GO:0051561	positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1	2.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	0.6	GO:1901317	regulation of sperm motility(GO:1901317)
0.0	3.4	GO:0009612	response to mechanical stimulus(GO:0009612)
0.0	0.7	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.4	GO:0001707	mesoderm formation(GO:0001707)
0.0	3.3	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.0	0.5	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	5.2	GO:0006954	inflammatory response(GO:0006954)
0.0	1.3	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	1.3	GO:0006956	complement activation(GO:0006956)
0.0	1.6	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.7	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.4	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	1.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	1.2	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	2.6	GO:0033334	fin morphogenesis(GO:0033334)
0.0	0.6	GO:0018216	peptidyl-arginine methylation(GO:0018216)
0.0	1.9	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	2.7	GO:0009308	amine metabolic process(GO:0009308)
0.0	2.8	GO:0055113	epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0	0.5	GO:0072310	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.6	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.7	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	1.6	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.0	3.8	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
0.0	3.2	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.0	0.8	GO:0021514	ventral spinal cord interneuron differentiation(GO:0021514)
0.0	0.5	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0	2.0	GO:0048484	enteric nervous system development(GO:0048484)
0.0	0.6	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	1.9	GO:0006414	translational elongation(GO:0006414)
0.0	1.2	GO:0043534	blood vessel endothelial cell migration(GO:0043534)
0.0	0.7	GO:0051283	sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) sequestering of metal ion(GO:0051238) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.0	1.6	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	1.1	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	1.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.6	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0009182	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.6	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0090151	protein import into mitochondrial inner membrane(GO:0045039) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0	0.5	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.4	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.5	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.7	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.0	0.1	GO:0045050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0	0.5	GO:0032526	response to retinoic acid(GO:0032526)
0.0	0.3	GO:0043270	positive regulation of ion transmembrane transporter activity(GO:0032414) positive regulation of transmembrane transport(GO:0034764) positive regulation of ion transmembrane transport(GO:0034767) positive regulation of ion transport(GO:0043270) positive regulation of cation transmembrane transport(GO:1904064)
0.0	0.1	GO:0003315	heart rudiment formation(GO:0003315)
0.0	0.6	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.2	GO:0022615	protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0	0.7	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.7	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.0	1.1	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	0.7	GO:1904029	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0	0.2	GO:0035196	production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0	1.5	GO:0030155	regulation of cell adhesion(GO:0030155)
0.0	0.3	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.7	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.3	GO:0006265	DNA topological change(GO:0006265)
0.0	0.5	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.6	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	1.1	GO:0002088	lens development in camera-type eye(GO:0002088)
0.0	0.3	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.9	GO:0007219	Notch signaling pathway(GO:0007219)
0.0	0.1	GO:0036372	opsin transport(GO:0036372)
0.0	2.6	GO:0006955	immune response(GO:0006955)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	5.3	GO:1990923	PET complex(GO:1990923)
0.8	3.1	GO:0005913	cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.7	2.1	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.7	3.4	GO:0097433	dense body(GO:0097433)
0.6	3.2	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.6	1.8	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.6	10.6	GO:0030057	desmosome(GO:0030057)
0.5	9.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.5	3.8	GO:0042613	MHC class II protein complex(GO:0042613)
0.4	1.3	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.4	2.0	GO:0031415	NatA complex(GO:0031415)
0.4	4.0	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.4	2.1	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3	1.4	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3	10.5	GO:0031672	A band(GO:0031672)
0.3	18.3	GO:0036379	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.3	1.1	GO:0031511	Mis6-Sim4 complex(GO:0031511)
0.3	2.2	GO:0005614	interstitial matrix(GO:0005614)
0.3	4.0	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.3	1.3	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.2	11.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	1.0	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2	0.9	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.2	3.8	GO:0042555	MCM complex(GO:0042555)
0.2	6.2	GO:0035861	site of double-strand break(GO:0035861)
0.2	9.7	GO:0031941	filamentous actin(GO:0031941)
0.2	0.8	GO:0030870	Mre11 complex(GO:0030870)
0.2	1.4	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2	1.3	GO:0070847	core mediator complex(GO:0070847)
0.2	2.1	GO:0061617	MICOS complex(GO:0061617)
0.2	0.9	GO:1990071	TRAPPII protein complex(GO:1990071)
0.2	1.8	GO:0032420	stereocilium(GO:0032420)
0.2	1.1	GO:1902636	kinociliary basal body(GO:1902636)
0.2	3.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.2	10.5	GO:0022626	cytosolic ribosome(GO:0022626)
0.2	8.5	GO:0005902	microvillus(GO:0005902)
0.2	3.2	GO:0016282	eukaryotic 43S preinitiation complex(GO:0016282)
0.2	3.7	GO:0001917	photoreceptor inner segment(GO:0001917)
0.2	2.7	GO:0031209	SCAR complex(GO:0031209)
0.2	2.6	GO:0000792	heterochromatin(GO:0000792)
0.2	1.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.2	0.6	GO:0008247	1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1	0.4	GO:0000939	condensed chromosome inner kinetochore(GO:0000939) condensed nuclear chromosome inner kinetochore(GO:0000941)
0.1	0.9	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	1.9	GO:0005922	connexon complex(GO:0005922)
0.1	15.1	GO:0005882	intermediate filament(GO:0005882)
0.1	2.4	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	3.1	GO:0030667	secretory granule membrane(GO:0030667)
0.1	1.8	GO:0000780	condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1	0.6	GO:0018444	translation release factor complex(GO:0018444)
0.1	0.5	GO:0031085	BLOC-3 complex(GO:0031085)
0.1	6.5	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1	42.8	GO:0031012	extracellular matrix(GO:0031012)
0.1	0.8	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	4.4	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.1	4.2	GO:0032587	ruffle membrane(GO:0032587)
0.1	2.8	GO:0005839	proteasome core complex(GO:0005839)
0.1	3.9	GO:0005581	collagen trimer(GO:0005581)
0.1	1.8	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	1.0	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1	0.8	GO:0070652	HAUS complex(GO:0070652)
0.1	2.1	GO:0001726	ruffle(GO:0001726)
0.1	3.2	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	2.4	GO:0008305	integrin complex(GO:0008305)
0.1	1.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	9.4	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	0.5	GO:0070695	FHF complex(GO:0070695)
0.1	0.9	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	91.3	GO:0005615	extracellular space(GO:0005615)
0.1	4.9	GO:0031225	anchored component of membrane(GO:0031225)
0.1	0.6	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	1.2	GO:0070187	telosome(GO:0070187)
0.1	1.1	GO:0098798	mitochondrial protein complex(GO:0098798)
0.1	7.7	GO:0030055	cell-substrate junction(GO:0030055)
0.1	1.1	GO:0031594	neuromuscular junction(GO:0031594)
0.1	0.9	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	7.5	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	4.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	1.2	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	12.4	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	0.9	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.1	0.2	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	4.1	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	2.2	GO:0032040	small-subunit processome(GO:0032040)
0.1	0.7	GO:0072546	ER membrane protein complex(GO:0072546)
0.1	6.8	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1	0.5	GO:0035060	brahma complex(GO:0035060)
0.1	1.1	GO:0098844	postsynaptic endocytic zone membrane(GO:0098844)
0.1	3.9	GO:0016324	apical plasma membrane(GO:0016324)
0.1	0.9	GO:0044545	NSL complex(GO:0044545)
0.1	0.3	GO:0000814	ESCRT II complex(GO:0000814)
0.1	0.9	GO:0005579	membrane attack complex(GO:0005579)
0.1	1.6	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	1.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	4.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.5	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1	2.0	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	0.7	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.9	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	2.9	GO:0005884	actin filament(GO:0005884)
0.0	2.9	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0	0.7	GO:0071565	nBAF complex(GO:0071565)
0.0	1.0	GO:0005844	polysome(GO:0005844)
0.0	2.5	GO:0031228	integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0	1.7	GO:0016592	mediator complex(GO:0016592)
0.0	0.7	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.8	GO:0005876	spindle microtubule(GO:0005876)
0.0	1.8	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	1.6	GO:0030139	endocytic vesicle(GO:0030139)
0.0	1.3	GO:0000776	kinetochore(GO:0000776)
0.0	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0032783	ELL-EAF complex(GO:0032783)
0.0	0.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	7.4	GO:0005740	mitochondrial envelope(GO:0005740)
0.0	4.3	GO:0005730	nucleolus(GO:0005730)
0.0	0.7	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	9.3	GO:0005739	mitochondrion(GO:0005739)
0.0	0.1	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	2.1	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.8	GO:0005814	centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.0	15.9	GO:0051059	NF-kappaB binding(GO:0051059)
3.0	9.1	GO:1901612	cardiolipin binding(GO:1901612)
2.4	7.2	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
2.0	7.9	GO:0070052	collagen V binding(GO:0070052)
1.8	7.0	GO:0015105	arsenite transmembrane transporter activity(GO:0015105)
1.3	4.0	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.3	4.0	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.3	3.9	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
1.2	8.5	GO:0045735	nutrient reservoir activity(GO:0045735)
1.2	3.5	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
1.0	13.5	GO:0016775	creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
1.0	13.4	GO:0070697	activin receptor binding(GO:0070697)
1.0	3.1	GO:0070097	delta-catenin binding(GO:0070097)
0.9	2.8	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.9	6.1	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.8	5.8	GO:0004974	leukotriene receptor activity(GO:0004974)
0.8	3.3	GO:0051139	calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.8	12.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.8	4.0	GO:0008184	phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.8	3.8	GO:1990518	ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.8	8.3	GO:0030172	troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.7	4.3	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.7	3.4	GO:0098973	structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.7	5.3	GO:0034584	piRNA binding(GO:0034584)
0.6	6.2	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.6	5.4	GO:0003834	beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.6	2.3	GO:0004361	glutaryl-CoA dehydrogenase activity(GO:0004361)
0.6	1.7	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6	6.3	GO:0005523	tropomyosin binding(GO:0005523)
0.6	3.4	GO:0004743	pyruvate kinase activity(GO:0004743)
0.5	3.8	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.5	2.7	GO:0008131	primary amine oxidase activity(GO:0008131)
0.5	2.1	GO:0051916	C-X-C chemokine receptor activity(GO:0016494) granulocyte colony-stimulating factor binding(GO:0051916)
0.5	9.0	GO:0032190	acrosin binding(GO:0032190)
0.5	7.9	GO:0031386	protein tag(GO:0031386)
0.5	2.9	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.5	2.4	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5	2.8	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.5	3.6	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.4	2.7	GO:0043914	NADPH:sulfur oxidoreductase activity(GO:0043914)
0.4	1.7	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.4	5.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.4	13.4	GO:0017147	Wnt-protein binding(GO:0017147)
0.4	6.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.4	2.8	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.4	4.4	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4	3.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.4	6.6	GO:0004382	guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.4	3.1	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.4	4.2	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.4	3.4	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.4	4.9	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.4	1.5	GO:0004419	hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.4	3.4	GO:0038064	protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.4	1.1	GO:0047777	(3S)-citramalyl-CoA lyase activity(GO:0047777)
0.4	1.5	GO:0031708	endothelin B receptor binding(GO:0031708)
0.4	1.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4	3.2	GO:0000048	peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.3	1.7	GO:0030116	glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.3	4.7	GO:0002020	protease binding(GO:0002020)
0.3	1.3	GO:0004092	carnitine O-acetyltransferase activity(GO:0004092)
0.3	3.3	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.3	2.9	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3	2.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.3	0.6	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.3	1.2	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
0.3	1.1	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3	1.1	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3	1.3	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3	1.3	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.3	7.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.3	0.8	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.3	3.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.3	1.3	GO:0031769	glucagon receptor binding(GO:0031769)
0.3	3.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.2	11.2	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.2	1.7	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.2	2.7	GO:0031995	insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2	0.7	GO:0005502	11-cis retinal binding(GO:0005502)
0.2	2.2	GO:0005113	patched binding(GO:0005113)
0.2	2.6	GO:0004046	aminoacylase activity(GO:0004046)
0.2	12.8	GO:0000146	microfilament motor activity(GO:0000146)
0.2	3.5	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.2	0.7	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2	1.6	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.2	0.4	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.2	1.8	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2	3.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	2.2	GO:0017091	AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2	0.9	GO:0008384	IkappaB kinase activity(GO:0008384)
0.2	3.6	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2	2.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.2	6.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.2	1.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2	2.0	GO:0052795	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2	3.6	GO:0051371	muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2	0.5	GO:0071077	coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2	6.5	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.2	1.3	GO:0043394	glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.2	0.6	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.2	2.4	GO:2001069	glycogen binding(GO:2001069)
0.2	0.8	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.2	2.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	2.8	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	3.1	GO:0042056	chemoattractant activity(GO:0042056)
0.1	3.8	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	1.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	1.7	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.4	GO:0015462	protein-transmembrane transporting ATPase activity(GO:0015462)
0.1	1.0	GO:1903924	estradiol binding(GO:1903924)
0.1	0.6	GO:0101006	protein histidine phosphatase activity(GO:0101006)
0.1	34.6	GO:0030246	carbohydrate binding(GO:0030246)
0.1	1.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	2.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	1.9	GO:0005243	gap junction channel activity(GO:0005243)
0.1	1.3	GO:0005042	netrin receptor activity(GO:0005042)
0.1	0.6	GO:1902388	ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1	2.0	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	5.9	GO:0043022	ribosome binding(GO:0043022)
0.1	0.8	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
0.1	2.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	0.9	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.9	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	3.0	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	0.3	GO:0030251	cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.1	25.2	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	1.7	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	1.6	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.1	5.7	GO:0004601	peroxidase activity(GO:0004601)
0.1	0.7	GO:0005035	death receptor activity(GO:0005035)
0.1	0.8	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	3.2	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.1	1.2	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.1	1.2	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1	2.1	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	7.9	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.1	1.8	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.1	1.4	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	1.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	3.5	GO:0035064	methylated histone binding(GO:0035064)
0.1	1.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	3.0	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.4	GO:0008459	chondroitin 6-sulfotransferase activity(GO:0008459)
0.1	18.2	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	0.4	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1	0.6	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	0.7	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	2.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	1.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	1.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.1	2.1	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1	1.1	GO:0005123	death receptor binding(GO:0005123) nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1	8.7	GO:0004896	cytokine receptor activity(GO:0004896)
0.1	0.9	GO:0047676	arachidonate-CoA ligase activity(GO:0047676)
0.1	11.9	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	4.4	GO:0030295	kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1	0.4	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	11.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	2.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.6	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.8	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.7	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.1	1.0	GO:0038191	neuropilin binding(GO:0038191)
0.1	1.7	GO:0005548	phospholipid transporter activity(GO:0005548)
0.1	1.3	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.1	0.9	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	1.1	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	1.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.9	GO:0043994	H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1	0.3	GO:0019779	Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1	1.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.2	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.1	0.5	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1	1.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.1	0.5	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.1	0.9	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.7	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1	1.9	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.5	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1	5.4	GO:0051082	unfolded protein binding(GO:0051082)
0.1	0.6	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	0.5	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.7	GO:0045503	dynein light chain binding(GO:0045503)
0.1	1.2	GO:0005112	Notch binding(GO:0005112)
0.1	0.3	GO:0030504	inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1	2.1	GO:0005126	cytokine receptor binding(GO:0005126)
0.1	1.7	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1	1.0	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.2	GO:0005461	UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0	2.3	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	29.4	GO:0003779	actin binding(GO:0003779)
0.0	3.1	GO:0003823	antigen binding(GO:0003823)
0.0	3.1	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.4	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.6	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.8	GO:0004860	protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0	17.4	GO:0005198	structural molecule activity(GO:0005198)
0.0	1.1	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.9	GO:0099604	ligand-gated calcium channel activity(GO:0099604)
0.0	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.9	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.9	GO:0008252	nucleotidase activity(GO:0008252)
0.0	1.5	GO:0005109	frizzled binding(GO:0005109)
0.0	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.7	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.9	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.3	GO:0043495	protein anchor(GO:0043495)
0.0	1.1	GO:0004532	3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.4	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	4.4	GO:0005179	hormone activity(GO:0005179)
0.0	1.5	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	1.9	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.4	GO:0005217	intracellular ligand-gated ion channel activity(GO:0005217) intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.5	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	2.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	1.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	1.4	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	4.7	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.0	2.1	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.3	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	1.5	GO:0005125	cytokine activity(GO:0005125)
0.0	1.3	GO:0004521	endoribonuclease activity(GO:0004521)
0.0	0.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.0	1.1	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	1.2	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	3.3	GO:0030414	peptidase inhibitor activity(GO:0030414)
0.0	0.3	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	11.2	GO:0046983	protein dimerization activity(GO:0046983)
0.0	0.3	GO:0019869	chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.1	GO:0070035	ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.1	GO:0016408	C-acyltransferase activity(GO:0016408)
0.0	0.6	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	1.3	GO:0008146	sulfotransferase activity(GO:0008146)
0.0	0.8	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.1	GO:0032977	membrane insertase activity(GO:0032977)
0.0	0.3	GO:0045182	translation regulator activity(GO:0045182)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	2.6	GO:0008194	UDP-glycosyltransferase activity(GO:0008194)
0.0	0.1	GO:0004540	ribonuclease activity(GO:0004540)
0.0	0.0	GO:0001164	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.2	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	1.0	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.8	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.8	7.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.6	7.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.5	0.9	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.5	9.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.4	18.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.4	0.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4	6.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.4	10.6	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.4	3.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4	15.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.3	2.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.2	2.6	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	3.9	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.2	1.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	7.8	NABA COLLAGENS	Genes encoding collagen proteins
0.2	2.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.2	1.8	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.2	4.0	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.2	3.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.2	0.9	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	1.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	2.8	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	1.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	7.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	2.6	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	3.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.9	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1	4.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	1.5	PID ARF6 PATHWAY	Arf6 signaling events
0.1	14.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	1.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	4.8	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	0.9	PID FGF PATHWAY	FGF signaling pathway
0.1	6.2	PID E2F PATHWAY	E2F transcription factor network
0.1	1.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	1.1	PID ALK2 PATHWAY	ALK2 signaling events
0.1	0.8	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	1.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	0.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	1.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	2.0	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	6.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	6.2	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.0	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.6	PID ATM PATHWAY	ATM pathway
0.0	1.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	1.0	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.7	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
1.2	9.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.9	9.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.7	5.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.6	7.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.5	3.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.4	4.0	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.4	1.3	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.4	2.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.4	4.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.3	2.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3	1.9	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.3	3.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	3.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.3	3.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	3.8	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2	6.0	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.2	2.5	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.2	2.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.2	2.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.2	0.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	4.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.2	11.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	1.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.2	3.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.2	4.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	2.5	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2	6.4	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.2	7.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	11.6	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	7.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	3.3	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	1.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	1.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.7	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.1	5.4	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	2.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.9	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	0.7	REACTOME OPSINS	Genes involved in Opsins
0.1	2.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	0.8	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.1	1.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	3.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	1.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	1.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	2.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	0.5	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	1.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	4.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.5	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	2.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	3.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	1.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	2.9	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	1.2	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	1.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.9	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.6	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	1.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.4	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0	0.3	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.3	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	1.6	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.3	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.4	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway

Results for tbr1b_tbx16+tbx16l+tbx2a+tbx2b

Z-value: 1.14

Motif logo

Transcription factors associated with tbr1b_tbx16+tbx16l+tbx2a+tbx2b

Activity-expression correlation:

Activity profile of tbr1b_tbx16+tbx16l+tbx2a+tbx2b motif

Sorted Z-values of tbr1b_tbx16+tbx16l+tbx2a+tbx2b motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of tbr1b_tbx16+tbx16l+tbx2a+tbx2b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: