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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for tcf21

Z-value: 1.11

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Transcription factors associated with tcf21

Gene Symbol Gene ID Gene Info
ENSDARG00000036869 transcription factor 21
ENSDARG00000111209 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf21dr11_v1_chr23_-_31555696_315556960.093.8e-01Click!

Activity profile of tcf21 motif

Sorted Z-values of tcf21 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_28830643 32.01 ENSDART00000051448
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr5_+_28849155 27.67 ENSDART00000079090
zgc:174259
chr5_+_28858345 22.22 ENSDART00000111180
si:ch211-186e20.2
chr11_-_5865744 19.16 ENSDART00000104360
guanidinoacetate N-methyltransferase
chr3_+_1055588 19.15 ENSDART00000143220
zgc:153921
chr5_+_28848870 14.22 ENSDART00000149563
zgc:174259
chr5_+_28857969 13.66 ENSDART00000149850
si:ch211-186e20.2
chr7_+_6652967 13.49 ENSDART00000102681
purine nucleoside phosphorylase 5a
chr16_+_23972126 13.27 ENSDART00000132742
ENSDART00000145330
apolipoprotein C-I
chr5_+_28830388 13.06 ENSDART00000149150
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr7_+_34794829 12.75 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
epithelial splicing regulatory protein 2
chr8_+_39724138 12.63 ENSDART00000009323
phospholipase A2, group IB (pancreas)
chr6_+_112579 11.76 ENSDART00000034505
adaptor-related protein complex 1, mu 2 subunit
chr7_+_10610791 11.39 ENSDART00000166064
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr20_+_42668875 10.43 ENSDART00000048890
solute carrier family 22 (organic cation transporter), member 2
chr3_-_21094437 8.67 ENSDART00000153739
ENSDART00000109790
nemo-like kinase, type 1
chr2_+_4208323 7.68 ENSDART00000167906
GATA binding protein 6
chr7_-_24364536 7.67 ENSDART00000064789
thioredoxin
chr9_-_35633827 7.15 ENSDART00000077745
zona pellucida glycoprotein 2, like 1
chr8_-_27687095 6.20 ENSDART00000086946
Moloney leukemia virus 10b, tandem duplicate 1
chr8_+_24747865 6.15 ENSDART00000078656
solute carrier family 16, member 4
chr7_+_49664174 6.13 ENSDART00000137059
ENSDART00000131210
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr25_+_3326885 6.06 ENSDART00000104866
lactate dehydrogenase Bb
chr15_+_20403084 6.04 ENSDART00000141388
ENSDART00000152734
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr24_+_22056386 5.97 ENSDART00000132390
ankyrin repeat domain 33ba
chr9_+_21146862 5.90 ENSDART00000136365
hydroxyacid oxidase 2 (long chain)
chr5_+_67448664 5.88 ENSDART00000105731
si:dkey-251i10.1
chr5_-_29152457 5.72 ENSDART00000078469
NADPH oxidase activator 1
chr24_+_37709191 5.63 ENSDART00000066558
2,4-dienoyl CoA reductase 2, peroxisomal
chr19_+_43119014 5.59 ENSDART00000023156
eukaryotic translation elongation factor 1 alpha 1, like 1
chr11_+_44503774 5.55 ENSDART00000169295
endoplasmic reticulum oxidoreductase beta
chr7_+_44715224 5.39 ENSDART00000184630
si:dkey-56m19.5
chr6_-_54348568 5.08 ENSDART00000156501
zgc:101577
chr15_-_39969988 5.01 ENSDART00000146054
ribosomal protein S5
chr1_-_52498146 4.95 ENSDART00000122217
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr16_-_31686602 4.93 ENSDART00000170357
complement component 1, s subcomponent
chr12_-_33859950 4.60 ENSDART00000131181
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Gb
chr1_-_52497834 4.54 ENSDART00000136469
ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr10_-_25217347 4.53 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr8_-_19280856 4.50 ENSDART00000100473
zgc:77486
chr10_+_31809226 4.43 ENSDART00000087898
forkhead box O1 b
chr4_-_75175407 4.33 ENSDART00000180125

chr21_-_20929575 4.30 ENSDART00000163889
complement component 6
chr19_+_7636941 4.29 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr5_+_25762271 4.27 ENSDART00000181323
transmembrane protein 2
chr25_-_7650335 4.24 ENSDART00000089034
myosin VAb
chr2_-_17114852 4.23 ENSDART00000006549
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr11_+_21910343 4.18 ENSDART00000161485
forkhead box P4
chr1_+_52560549 4.18 ENSDART00000167514
ATP-binding cassette, sub-family A (ABC1), member 1A
chr15_+_29276508 3.99 ENSDART00000170537
ENSDART00000126559
RAP1 GTPase activating protein 2a
chr8_+_45334255 3.82 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr14_-_34605607 3.81 ENSDART00000191608
actin filament associated protein 1-like 1a
chr22_-_16154771 3.76 ENSDART00000009464
solute carrier family 30 (zinc transporter), member 7
chr13_+_40770628 3.45 ENSDART00000085846
NK1 transcription factor related 2-like,a
chr21_-_37435162 3.43 ENSDART00000133585
family with sequence similarity 114, member A2
chr19_+_43119698 3.36 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eukaryotic translation elongation factor 1 alpha 1, like 1
chr20_-_26551210 3.36 ENSDART00000077715
si:dkey-25e12.3
chr6_+_42475730 3.34 ENSDART00000150226
macrophage stimulating 1 receptor a
chr2_-_17115256 3.25 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr15_-_18067220 3.23 ENSDART00000113142
pleckstrin homology-like domain, family B, member 1b
chr2_+_32016516 3.22 ENSDART00000135040
MYC proto-oncogene, bHLH transcription factor b
chr10_-_44560165 3.13 ENSDART00000181217
ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr21_-_293146 3.12 ENSDART00000157781
plasminogen receptor, C-terminal lysine transmembrane protein
chr15_-_25365319 3.10 ENSDART00000152651
clustered mitochondria (cluA/CLU1) homolog a
chr21_+_19418563 3.09 ENSDART00000181113
ENSDART00000080110
alpha-methylacyl-CoA racemase
chr1_+_33390286 3.05 ENSDART00000139004
dehydrogenase/reductase (SDR family) X-linked
chr2_+_32016256 2.96 ENSDART00000005143
MYC proto-oncogene, bHLH transcription factor b
chr7_-_17690756 2.92 ENSDART00000173759
mitogen-activated protein kinase kinase kinase kinase 2
chr10_+_29849977 2.91 ENSDART00000180242
heat shock protein 8
chr17_+_8323348 2.90 ENSDART00000169900
CDC42 binding protein kinase alpha (DMPK-like) a
chr7_-_24046999 2.88 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dehydrogenase/reductase (SDR family) member 4
chr13_+_11876437 2.87 ENSDART00000179753
tripartite motif containing 8a
chr9_-_12811936 2.87 ENSDART00000188490
myosin X-like 3
chr14_-_34605804 2.86 ENSDART00000144547
actin filament associated protein 1-like 1a
chr3_-_14571514 2.85 ENSDART00000137197
SWIM-type zinc finger 7 associated protein 1
chr5_-_13315726 2.83 ENSDART00000143364
stromal cell-derived factor 2-like 1
chr3_-_34724879 2.82 ENSDART00000177021
thyroid hormone receptor alpha a
chr10_+_29850330 2.75 ENSDART00000168898
heat shock protein 8
chr24_-_25166416 2.74 ENSDART00000111552
ENSDART00000169495
pleckstrin homology-like domain, family B, member 2b
chr21_-_45685063 2.67 ENSDART00000162422
secretion associated, Ras related GTPase 1B
chr17_+_53156530 2.66 ENSDART00000126277
ENSDART00000156774
diphthamine biosynthesis 6
chr13_+_24584401 2.63 ENSDART00000057599
fucose mutarotase
chr9_-_49531762 2.61 ENSDART00000121875
xin actin binding repeat containing 2b
chr15_+_6459847 2.57 ENSDART00000157250
ENSDART00000065824
beta-site APP-cleaving enzyme 2
chr18_-_7948188 2.55 ENSDART00000091805
SH3 and multiple ankyrin repeat domains 3a
chr11_-_41966854 2.55 ENSDART00000055709
hairy-related 2
chr6_-_40352215 2.55 ENSDART00000103992
tubulin tyrosine ligase-like family, member 3
chr19_+_2877079 2.53 ENSDART00000160847
HGH1 homolog (S. cerevisiae)
chr7_-_6357952 2.50 ENSDART00000173197
zgc:165555
chr13_-_24260609 2.44 ENSDART00000138747
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr4_-_685412 2.41 ENSDART00000168167
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr6_-_39344259 2.39 ENSDART00000104074
zgc:158846
chr7_-_66864756 2.39 ENSDART00000184462
ENSDART00000189424
adenosine monophosphate deaminase 3a
chr17_+_4368859 2.38 ENSDART00000055385
cardiolipin synthase 1
chr15_+_32727848 2.36 ENSDART00000161361
periostin, osteoblast specific factor b
chr1_-_20593778 2.34 ENSDART00000124770
UDP glycosyltransferase 8
chr23_-_44470253 2.30 ENSDART00000176333
si:ch1073-228j22.2
chr11_+_21096339 2.27 ENSDART00000124574
interleukin 19 like
chr1_+_56843411 2.21 ENSDART00000152312
si:ch211-152f2.1
chr17_-_14836320 2.20 ENSDART00000157051
nidogen 2a (osteonidogen)
chr7_-_17690983 2.16 ENSDART00000009367
mitogen-activated protein kinase kinase kinase kinase 2
chr7_-_24047316 2.16 ENSDART00000184799
dehydrogenase/reductase (SDR family) member 4
chr8_-_25247284 2.14 ENSDART00000132697
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr24_-_25166720 2.13 ENSDART00000141601
pleckstrin homology-like domain, family B, member 2b
chr22_-_10470663 2.13 ENSDART00000143352
osteomodulin
chr22_-_4798738 2.12 ENSDART00000114465
zgc:195170
chr24_-_11905911 2.11 ENSDART00000033621
transmembrane 9 superfamily member 1
chr9_-_39624173 2.10 ENSDART00000180106
ENSDART00000126766
erb-b2 receptor tyrosine kinase 4b
chr8_+_14058646 2.05 ENSDART00000080852
UDP glucuronosyltransferase 5 family, polypeptide E1
chr12_+_20693743 2.03 ENSDART00000153023
ENSDART00000153370
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr21_-_12749501 2.02 ENSDART00000179724

chr10_-_7892192 2.01 ENSDART00000145480
smoothelin a
chr10_+_24445698 1.98 ENSDART00000146370
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr3_-_41715690 1.97 ENSDART00000184703

chr6_-_8360918 1.97 ENSDART00000004716
acid phosphatase 5a, tartrate resistant
chr17_+_38030327 1.95 ENSDART00000085481
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr10_+_26935155 1.94 ENSDART00000129993

chr10_+_35491216 1.93 ENSDART00000109705
pleckstrin homology-like domain, family B, member 2a
chr6_-_31224563 1.89 ENSDART00000104616
leptin receptor
chr21_+_21357309 1.88 ENSDART00000079634
ENSDART00000146102
potassium channel, subfamily K, member 12 like
chr18_+_33132266 1.87 ENSDART00000151623
si:ch211-229c8.14
chr16_-_1709328 1.85 ENSDART00000168865
activating signal cointegrator 1 complex subunit 3
chr5_-_64900552 1.85 ENSDART00000073963
si:ch211-236k19.2
chr5_+_23630384 1.83 ENSDART00000013745
connexin 39.9
chr22_-_22231720 1.80 ENSDART00000160165
adaptor-related protein complex 3, delta 1 subunit
chr22_-_37738203 1.80 ENSDART00000143190
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr17_+_8799451 1.79 ENSDART00000189814
ENSDART00000191577
tonsoku-like, DNA repair protein
chr9_+_3519191 1.77 ENSDART00000008606
methyltransferase like 8
chr14_+_5835134 1.77 ENSDART00000054867
ancient ubiquitous protein 1
chr5_+_50879545 1.75 ENSDART00000128402
nucleolar protein 6 (RNA-associated)
chr25_-_24216980 1.73 ENSDART00000135349
si:dkeyp-19e1.4
chr15_-_18197008 1.69 ENSDART00000147632
si:ch211-247l8.8
chr22_-_10891213 1.68 ENSDART00000145229
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr14_+_80685 1.67 ENSDART00000188443
stromal antigen 3
chr4_-_18635005 1.63 ENSDART00000125361
peroxisome proliferator-activated receptor alpha a
chr5_+_58455488 1.63 ENSDART00000038602
ENSDART00000127958
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr13_-_280827 1.61 ENSDART00000144819
solute carrier family 30 (zinc transporter), member 6
chr18_-_26797723 1.61 ENSDART00000008013
SEC11 homolog A, signal peptidase complex subunit
chr1_-_34450784 1.60 ENSDART00000140515
LIM domain 7b
chr19_+_31541607 1.60 ENSDART00000181604
geminin, DNA replication inhibitor
chr2_+_30481125 1.59 ENSDART00000125933
family with sequence similarity 173, member B
chr13_+_11876145 1.59 ENSDART00000128249
tripartite motif containing 8a
chr1_-_34450622 1.58 ENSDART00000083736
LIM domain 7b
chr25_-_19655820 1.57 ENSDART00000149585
ENSDART00000104353
ATPase plasma membrane Ca2+ transporting 1b
chr24_-_35282568 1.57 ENSDART00000167406
ENSDART00000088609
syntrophin, gamma 1
chr7_+_30051880 1.57 ENSDART00000075609
proline-serine-threonine phosphatase interacting protein 1b
chr24_+_4434117 1.56 ENSDART00000184349
gap junction protein delta 4
chr14_-_26465729 1.56 ENSDART00000143454
synovial apoptosis inhibitor 1, synoviolin
chr16_-_42750295 1.55 ENSDART00000176570
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr20_-_42439896 1.51 ENSDART00000061049
vestigial-like family member 2a
chr18_+_34861568 1.50 ENSDART00000192825

chr20_-_18789543 1.50 ENSDART00000182240
cerebral cavernous malformation 2
chr2_-_31833347 1.49 ENSDART00000109460
nucleolar protein 7
chr7_+_1473929 1.49 ENSDART00000050687
lysophosphatidylcholine acyltransferase 4
chr3_-_12227359 1.48 ENSDART00000167356
transcription factor AP-4 (activating enhancer binding protein 4)
chr4_-_17680493 1.48 ENSDART00000180131

chr8_+_30456161 1.43 ENSDART00000085894
phosphoglucomutase 5
chr16_-_12291045 1.43 ENSDART00000185447

chr12_-_9294819 1.40 ENSDART00000003805
parathyroid hormone 1 receptor b
chr7_+_27277236 1.40 ENSDART00000185161
SRY (sex determining region Y)-box 6
chr18_-_10995410 1.40 ENSDART00000136751
tetraspanin 33b
chr7_+_4971938 1.39 ENSDART00000172889
ENSDART00000145389
si:dkey-81n2.2
chr1_-_40911332 1.38 ENSDART00000027463
H6 family homeobox 4
chr5_-_24238733 1.38 ENSDART00000138170
phospholipid scramblase 3a
chr12_+_2660733 1.38 ENSDART00000152235
interphotoreceptor retinoid-binding protein like
chr12_+_30360184 1.36 ENSDART00000190718
si:ch211-225b10.3
chr11_-_308838 1.35 ENSDART00000112538
POC1 centriolar protein A
chr6_-_39218609 1.35 ENSDART00000133305
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr4_-_43374443 1.33 ENSDART00000191022

chr3_+_58379450 1.33 ENSDART00000155759
short chain dehydrogenase/reductase family 42E, member 2
chr16_+_47428721 1.30 ENSDART00000180597
ENSDART00000032309
solute carrier family 25 (mitochondrial folate carrier), member 32b
chr2_+_29257942 1.29 ENSDART00000184362
ENSDART00000025562
cadherin 18, type 2a
chr15_+_37954666 1.28 ENSDART00000126534
ENSDART00000155548
si:dkey-238d18.7
chr13_+_2625150 1.25 ENSDART00000164177
phospholipid phosphatase 4
chr5_-_57480660 1.25 ENSDART00000147875
ENSDART00000142776
si:ch211-202f5.2
chr5_+_60886103 1.24 ENSDART00000009298
transmembrane protein 248
chr5_-_23729590 1.24 ENSDART00000014831
si:dkey-110k5.10
chr14_+_34952883 1.22 ENSDART00000182812
interleukin 12Ba
chr1_+_20593653 1.22 ENSDART00000132440
si:ch211-142c4.1
chr13_+_21601149 1.20 ENSDART00000179369
SH2 domain containing 4Ba
chr6_+_37752781 1.20 ENSDART00000154364
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr18_+_19820008 1.20 ENSDART00000079691
ENSDART00000135049
IQ motif containing H
chr22_+_14102397 1.20 ENSDART00000146397
ENSDART00000137530
hatching enzyme 1, tandem duplicate 3
chr21_+_39185461 1.20 ENSDART00000178419
crystallin, beta A1b
chr8_+_22405477 1.20 ENSDART00000148267
si:dkey-23c22.7
chr20_+_18163355 1.20 ENSDART00000011287
aquaporin 4
chr15_-_945804 1.20 ENSDART00000063257
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr21_-_11632403 1.19 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
calpastatin
chr10_+_1590604 1.18 ENSDART00000166646
olfactory receptor class A related 5
chr6_+_25261297 1.17 ENSDART00000162824
ENSDART00000163490
ENSDART00000157790
ENSDART00000160978
ENSDART00000161545
ENSDART00000159978
kynurenine aminotransferase 3
chr14_+_7939398 1.16 ENSDART00000189773
CXXC finger protein 5b
chr2_+_17556177 1.16 ENSDART00000074113
Pim proto-oncogene, serine/threonine kinase, related 197
chr5_-_24008997 1.16 ENSDART00000066645
eukaryotic translation initiation factor 1A, X-linked, a
chr2_+_44977889 1.16 ENSDART00000144024
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr5_-_65121747 1.15 ENSDART00000165556
torsin family 2, member A
chr25_+_36045072 1.15 ENSDART00000126326
RPGRIP1-like
chr21_-_39253647 1.14 ENSDART00000133034
tumor suppressor candidate 5b
chr11_-_11266882 1.14 ENSDART00000020256
lengsin, lens protein with glutamine synthetase domain
chr4_-_21466480 1.12 ENSDART00000139962
PRKC, apoptosis, WT1, regulator
chr15_-_38009344 1.12 ENSDART00000157094
si:dkey-238d18.6

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.2 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
4.4 13.3 GO:0032369 negative regulation of lipid transport(GO:0032369) negative regulation of lipid catabolic process(GO:0050995)
3.5 10.4 GO:0015695 organic cation transport(GO:0015695)
1.9 11.4 GO:0006572 tyrosine catabolic process(GO:0006572)
1.5 7.7 GO:0043011 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
1.5 5.9 GO:0015860 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
1.4 124.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
1.2 6.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.0 4.2 GO:0010874 regulation of cholesterol efflux(GO:0010874)
1.0 3.1 GO:0010755 regulation of plasminogen activation(GO:0010755)
1.0 6.0 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
1.0 7.7 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.9 5.7 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.9 5.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.9 12.6 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.7 5.7 GO:0042554 superoxide anion generation(GO:0042554)
0.7 2.7 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.6 7.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.6 1.8 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.5 1.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 1.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.4 4.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.4 2.7 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.4 2.6 GO:0006004 fucose metabolic process(GO:0006004)
0.4 2.6 GO:0007405 neuroblast proliferation(GO:0007405)
0.4 4.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 2.6 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.3 1.0 GO:0010658 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.3 2.4 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.3 4.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.3 2.8 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.2 8.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 1.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 1.8 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2 1.8 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.2 5.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 2.2 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.2 3.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.2 11.8 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.2 2.1 GO:0050909 sensory perception of taste(GO:0050909)
0.2 2.7 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.2 0.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.2 1.6 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.2 2.0 GO:0045453 bone resorption(GO:0045453)
0.2 5.4 GO:0006829 zinc II ion transport(GO:0006829)
0.2 1.6 GO:0006465 signal peptide processing(GO:0006465)
0.2 1.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 0.5 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 0.5 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 1.4 GO:0060612 adipose tissue development(GO:0060612)
0.1 8.9 GO:0006414 translational elongation(GO:0006414)
0.1 1.2 GO:0006833 water transport(GO:0006833)
0.1 3.7 GO:0019835 cytolysis(GO:0019835)
0.1 0.9 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 1.4 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 1.1 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.2 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 1.2 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.7 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.8 GO:0031297 replication fork processing(GO:0031297)
0.1 4.9 GO:0031638 zymogen activation(GO:0031638)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 1.9 GO:0009749 response to glucose(GO:0009749)
0.1 1.1 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 1.6 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 2.1 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.1 1.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.1 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 0.5 GO:0032475 otolith formation(GO:0032475)
0.1 4.6 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 5.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.0 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 2.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.8 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.7 GO:0032196 transposition(GO:0032196)
0.1 2.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.5 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.9 GO:0006265 DNA topological change(GO:0006265)
0.1 8.8 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.1 4.4 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.2 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 1.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 7.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 2.2 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.5 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 1.7 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.8 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 1.5 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.1 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 1.1 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 2.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 6.0 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 1.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 2.6 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 5.0 GO:0007601 visual perception(GO:0007601)
0.0 3.2 GO:0001947 heart looping(GO:0001947)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.6 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 1.4 GO:0006006 glucose metabolic process(GO:0006006)
0.0 3.6 GO:0006631 fatty acid metabolic process(GO:0006631)
0.0 1.3 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.4 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 1.4 GO:0051604 protein maturation(GO:0051604)
0.0 1.5 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.9 GO:0051170 nuclear import(GO:0051170)
0.0 0.3 GO:0097061 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 1.1 GO:0001756 somitogenesis(GO:0001756)
0.0 1.2 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 13.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.7 5.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 1.8 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.6 3.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.5 6.7 GO:0002102 podosome(GO:0002102)
0.4 13.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 1.6 GO:0005787 signal peptidase complex(GO:0005787)
0.3 2.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.3 1.2 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.3 4.3 GO:0005579 membrane attack complex(GO:0005579)
0.3 5.4 GO:0009925 basal plasma membrane(GO:0009925)
0.3 1.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.3 1.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 2.4 GO:0045095 keratin filament(GO:0045095)
0.2 1.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 6.2 GO:0043186 P granule(GO:0043186)
0.2 7.5 GO:0005657 replication fork(GO:0005657)
0.1 2.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 3.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 5.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.8 GO:1990391 DNA repair complex(GO:1990391)
0.1 134.6 GO:0005615 extracellular space(GO:0005615)
0.1 11.0 GO:0016324 apical plasma membrane(GO:0016324)
0.1 2.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 2.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 2.1 GO:0045178 basal part of cell(GO:0045178)
0.1 6.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 1.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 9.4 GO:0016459 myosin complex(GO:0016459)
0.1 1.7 GO:0008278 cohesin complex(GO:0008278)
0.1 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 2.9 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 2.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.7 GO:0000786 nucleosome(GO:0000786)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 5.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 13.1 GO:0005576 extracellular region(GO:0005576)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 1.8 GO:0016607 nuclear speck(GO:0016607)
0.0 3.3 GO:0005730 nucleolus(GO:0005730)
0.0 7.9 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.6 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.4 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
2.1 6.2 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
1.5 13.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.5 7.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
1.5 5.9 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
1.0 13.3 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
1.0 118.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.9 2.6 GO:0042806 fucose binding(GO:0042806)
0.9 10.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.9 6.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.9 9.5 GO:0004046 aminoacylase activity(GO:0004046)
0.8 2.5 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.8 5.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.8 4.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6 5.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.5 1.6 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.5 11.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4 1.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.4 1.3 GO:0015230 folic acid transporter activity(GO:0008517) FAD transmembrane transporter activity(GO:0015230)
0.4 5.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 3.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.4 9.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.4 5.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.4 2.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 1.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 1.5 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.3 1.2 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.3 1.8 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.3 1.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 7.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.3 3.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 5.9 GO:0010181 FMN binding(GO:0010181)
0.3 4.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 2.0 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 5.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 6.0 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 8.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 7.1 GO:0004707 MAP kinase activity(GO:0004707)
0.2 5.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 1.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.2 1.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 0.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.2 GO:0015250 water channel activity(GO:0015250)
0.1 1.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.8 GO:0004630 phospholipase D activity(GO:0004630)
0.1 6.7 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 1.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 6.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 5.0 GO:0019843 rRNA binding(GO:0019843)
0.1 2.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 2.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 2.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 16.6 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.1 1.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 4.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.9 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.9 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.4 GO:0019840 retinoid binding(GO:0005501) isoprenoid binding(GO:0019840)
0.1 1.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 4.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 3.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.0 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 2.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 7.6 GO:0003774 motor activity(GO:0003774)
0.0 2.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 3.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 2.5 GO:0019955 cytokine binding(GO:0019955)
0.0 1.0 GO:0019838 growth factor binding(GO:0019838)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 6.0 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 12.2 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 44.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 13.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 7.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 5.1 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.1 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 7.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 5.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 1.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 5.3 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
3.2 12.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
1.5 7.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.1 11.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.6 3.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.6 3.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 4.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.4 5.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.4 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 4.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 3.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 2.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 1.6 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.2 2.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 31.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 1.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 5.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 7.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.8 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 0.5 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation