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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for thraa+thrab

Z-value: 0.84

Motif logo

Transcription factors associated with thraa+thrab

Gene Symbol Gene ID Gene Info
ENSDARG00000000151 thyroid hormone receptor alpha a
ENSDARG00000052654 thyroid hormone receptor alpha b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
thraadr11_v1_chr3_-_34753605_34753605-0.533.4e-08Click!
thrabdr11_v1_chr12_-_22039350_22039350-0.347.1e-04Click!

Activity profile of thraa+thrab motif

Sorted Z-values of thraa+thrab motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_22249636 8.46 ENSDART00000108472
ENSDART00000173123
synaptopodin 2-like a
chr19_+_30990815 7.70 ENSDART00000134645
syncoilin, intermediate filament protein
chr7_+_31871830 7.30 ENSDART00000139899
myosin binding protein C, cardiac
chr3_+_33300522 7.17 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr14_-_7128980 6.93 ENSDART00000171311
si:ch73-43g23.1
chr2_+_42191592 6.92 ENSDART00000144716
caveolae associated protein 4a
chr10_+_6318227 6.39 ENSDART00000170872
ENSDART00000162428
ENSDART00000158994
tropomyosin 2 (beta)
chr6_+_41463786 6.25 ENSDART00000065006
twinfilin actin-binding protein 2a
chr16_-_2818170 5.86 ENSDART00000081918
acyl-CoA thioesterase 22
chr9_-_22892838 5.37 ENSDART00000143888
nebulin
chr5_-_38820046 5.29 ENSDART00000182886
CCR4-NOT transcription complex, subunit 6-like
chr20_-_26001288 5.12 ENSDART00000136518
ENSDART00000063177
calpain 3b
chr9_-_49493305 4.89 ENSDART00000148707
ENSDART00000148561
xin actin binding repeat containing 2b
chr12_-_3133483 4.25 ENSDART00000015092
collagen, type I, alpha 1b
chr18_+_26750516 4.18 ENSDART00000110843
alpha-kinase 3a
chr15_+_24644016 4.02 ENSDART00000043292
smoothelin, like
chr19_-_32804535 3.77 ENSDART00000175613
ENSDART00000052098
5'-nucleotidase, cytosolic IAa
chr8_-_2434282 3.73 ENSDART00000137262
ENSDART00000134044
voltage-dependent anion channel 3
chr12_-_26415499 3.53 ENSDART00000185779
synaptopodin 2-like b
chr23_+_26026383 3.41 ENSDART00000141553
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr11_+_42585138 3.27 ENSDART00000019008
ankyrin repeat and SOCS box containing 14a
chr10_-_39153959 3.21 ENSDART00000150193
ENSDART00000111362
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr4_+_38344 3.11 ENSDART00000170197
ENSDART00000175348
putative homeodomain transcription factor 2
chr25_-_29611476 3.10 ENSDART00000154458
si:ch211-253p14.2
chr9_+_54644626 3.07 ENSDART00000190609
EGF-like-domain, multiple 6
chr18_+_36037223 3.06 ENSDART00000144410
transmembrane protein 91
chr18_+_8340886 3.05 ENSDART00000081132
carnitine palmitoyltransferase 1B (muscle)
chr13_+_24853578 3.00 ENSDART00000145865
si:dkey-24f15.2
chr12_-_29305533 2.95 ENSDART00000189410
SH2 domain containing 4Bb
chr10_-_39154594 2.80 ENSDART00000148825
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr13_+_51869025 2.67 ENSDART00000187066

chr1_-_38813679 2.60 ENSDART00000148917
ankyrin repeat and SOCS box containing 5b
chr11_+_6010177 2.60 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
GTP binding protein 3, mitochondrial
chr22_-_10470663 2.59 ENSDART00000143352
osteomodulin
chr11_-_25213651 2.58 ENSDART00000097316
ENSDART00000152186
myosin, heavy chain 7B, cardiac muscle, beta a
chr11_+_42587900 2.49 ENSDART00000167529
ankyrin repeat and SOCS box containing 14a
chr9_+_15893093 2.45 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
chr23_+_44634187 2.28 ENSDART00000143688
si:ch73-265d7.2
chr5_+_36439405 2.28 ENSDART00000102973
ectodysplasin A
chr5_-_33286820 2.26 ENSDART00000184426
ribosomal protein L7a
chr21_+_39185761 2.24 ENSDART00000075992
ENSDART00000140644
crystallin, beta A1b
chr3_+_29600917 2.23 ENSDART00000048867
somatostatin receptor 3
chr19_+_19600297 2.21 ENSDART00000160134
ENSDART00000183493
3-hydroxyisobutyrate dehydrogenase a
chr12_+_27589607 2.20 ENSDART00000066288
spermatogenesis associated 20
chr7_+_27455321 2.19 ENSDART00000148417
cytochrome P450, family 2, subfamily R, polypeptide 1
chr7_-_51528661 2.19 ENSDART00000174263
NHS-like 2
chr6_+_27339962 2.19 ENSDART00000193726
kelch-like family member 30
chr1_-_49250490 2.17 ENSDART00000150386
si:ch73-6k14.2
chr2_-_6182098 2.15 ENSDART00000156167
si:ch73-182a11.2
chr11_-_12198765 2.13 ENSDART00000104203
ENSDART00000128364
ENSDART00000166887
ENSDART00000041533
kertain 95
chr11_+_12897004 2.10 ENSDART00000152007
si:dkey-11m19.5
chr5_+_15350954 2.08 ENSDART00000140990
ENSDART00000137287
ENSDART00000061653
phosphatidylethanolamine binding protein 1
chr22_-_34995333 2.08 ENSDART00000110900
Kv channel interacting protein 2
chr4_-_16853464 2.07 ENSDART00000125743
ENSDART00000164570
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a
chr4_+_70414733 2.06 ENSDART00000162778
si:dkey-190j3.3
chr4_-_37479395 2.04 ENSDART00000168299
ENSDART00000157864
si:dkey-106c17.2
chr13_+_8677166 1.98 ENSDART00000181016
ENSDART00000135028
PROP paired-like homeobox 1
chr13_-_31435137 1.98 ENSDART00000057441
reticulon 1a
chr9_-_374693 1.96 ENSDART00000166571
si:dkey-11f4.7
chr15_-_5222924 1.95 ENSDART00000128924
odorant receptor, family E, subfamily 128, member 4
chr6_-_13783604 1.95 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
crystallin, beta A2a
chr6_+_39279831 1.92 ENSDART00000155088
ankyrin repeat domain 33Ab
chr11_+_25477643 1.92 ENSDART00000065941
opsin 1 (cone pigments), long-wave-sensitive, 1
chr20_+_42761881 1.91 ENSDART00000113625
Pim proto-oncogene, serine/threonine kinase, related 113
chr7_-_11638126 1.90 ENSDART00000125827
si:dkey-15b23.3
chr15_-_5239536 1.90 ENSDART00000081704
odorant receptor, family E, subfamily 128, member 2
chr8_+_20776654 1.90 ENSDART00000135850
nuclear factor I/C
chr6_-_6254432 1.86 ENSDART00000081952
reticulon 4a
chr4_-_16412084 1.86 ENSDART00000188460
decorin
chr4_+_70563225 1.85 ENSDART00000159508
si:dkey-11d20.1
chr6_-_29537219 1.82 ENSDART00000180262
peroxisomal biogenesis factor 5-like a
chr4_+_9011448 1.79 ENSDART00000192357
sorting and assembly machinery component 50 homolog, like
chr19_-_6988837 1.78 ENSDART00000145741
ENSDART00000167640
zinc finger protein 384 like
chr10_+_7564106 1.78 ENSDART00000159042
purine-rich element binding protein G
chr4_+_18489207 1.75 ENSDART00000135276
si:dkey-202b22.5
chr12_+_49125510 1.73 ENSDART00000185804

chr10_+_22775253 1.73 ENSDART00000190141
transmembrane protein 88 a
chr20_+_39457598 1.72 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr21_+_170038 1.72 ENSDART00000157614
kelch-like family member 8
chr11_+_45422206 1.71 ENSDART00000182548
HRAS-like suppressor
chr16_-_17175731 1.70 ENSDART00000183057
opsin 9
chr11_-_11471857 1.70 ENSDART00000030103
keratin 94
chr9_-_22129788 1.68 ENSDART00000124272
ENSDART00000175417
crystallin, gamma M2d8
chr16_-_41867833 1.68 ENSDART00000133066
zgc:194418
chr5_+_7989210 1.64 ENSDART00000168071
glial cell derived neurotrophic factor b
chr9_-_10778615 1.64 ENSDART00000182577

chr6_+_475264 1.62 ENSDART00000193615

chr14_+_5383060 1.62 ENSDART00000187825
ladybird homeobox 2
chr1_+_29096881 1.59 ENSDART00000075539
crystallin, alpha A
chr7_-_22699716 1.57 ENSDART00000193773

chr20_-_43462190 1.56 ENSDART00000100697
Pim proto-oncogene, serine/threonine kinase, related 133
chr15_-_5157572 1.56 ENSDART00000174192
odorant receptor, family E, subfamily 128, member 10
chr13_+_2523032 1.56 ENSDART00000172261
luteinizing hormone, beta polypeptide
chr7_+_27251376 1.55 ENSDART00000173521
ENSDART00000173962
SRY (sex determining region Y)-box 6
chr6_+_39279104 1.55 ENSDART00000023686
ankyrin repeat domain 33Ab
chr20_+_54738210 1.54 ENSDART00000151399
p21 protein (Cdc42/Rac)-activated kinase 7
chr20_-_43572763 1.54 ENSDART00000153251
Pim proto-oncogene, serine/threonine kinase, related 125
chr22_+_1092479 1.54 ENSDART00000170119
guanylate cyclase activator 1e
chr23_+_24272421 1.53 ENSDART00000029974
chloride channel K
chr3_-_1400309 1.52 ENSDART00000159893
WW domain binding protein 11
chr16_-_5721386 1.51 ENSDART00000136655
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr8_+_32742650 1.50 ENSDART00000138117
hemicentin 2
chr10_+_26813710 1.50 ENSDART00000136122
si:ch211-263p13.7
chr16_+_4907690 1.49 ENSDART00000181100
family with sequence similarity 46 member A
chr20_+_42780162 1.49 ENSDART00000127069
Pim proto-oncogene, serine/threonine kinase, related 213
chr2_-_2380872 1.49 ENSDART00000147808
parathyroid hormone 1 receptor a
chr24_-_37698796 1.47 ENSDART00000172178
si:ch211-231f6.6
chr15_-_47812268 1.47 ENSDART00000190231
transmembrane O-methyltransferase
chr2_+_24786765 1.45 ENSDART00000141030
phosphodiesterase 4C, cAMP-specific a
chr9_-_30371247 1.45 ENSDART00000079068
ankyrin repeat and SOCS box containing 11
chr2_+_10127762 1.44 ENSDART00000100726
insulin-like 5b
chr1_+_57311901 1.44 ENSDART00000149397
mycbp associated protein
chr15_-_28095532 1.43 ENSDART00000191490
crystallin, beta A1a
chr3_-_34115886 1.42 ENSDART00000151531
immunoglobulin heavy variable 4-1
chr23_+_45822935 1.42 ENSDART00000161892
vitamin D receptor a
chr21_+_39185461 1.42 ENSDART00000178419
crystallin, beta A1b
chr1_+_57187794 1.41 ENSDART00000152485
si:dkey-27j5.9
chr20_-_7992496 1.41 ENSDART00000145521
phospholipid phosphatase 3
chr8_+_32747612 1.39 ENSDART00000142824
hemicentin 2
chr5_-_58840971 1.39 ENSDART00000050932
transmembrane protein 136b
chr23_-_45705525 1.39 ENSDART00000148959
endothelin receptor type Ab
chr17_+_9040165 1.38 ENSDART00000181221
ENSDART00000181846
A kinase (PRKA) anchor protein 6
chr5_-_67629263 1.37 ENSDART00000133753
zinc finger and BTB domain containing 20
chr11_-_1400507 1.37 ENSDART00000173029
ENSDART00000172953
ENSDART00000111140
ribosomal protein L29
chr9_-_22272181 1.37 ENSDART00000113174
crystallin, gamma M2d7
chr19_-_22507715 1.36 ENSDART00000160153
plectin a
chr5_+_27440325 1.34 ENSDART00000185815
ENSDART00000144013
lysyl oxidase-like 2b
chr3_-_1408487 1.33 ENSDART00000100845
bone gamma-carboxyglutamate (gla) protein
chr12_-_30841679 1.32 ENSDART00000105594
crystallin, gamma MX
chr25_+_16895294 1.32 ENSDART00000159773
zgc:77158
chr15_-_5217693 1.32 ENSDART00000134940
odorant receptor, family E, subfamily 128, member 5
chr11_-_40742424 1.32 ENSDART00000173399
ENSDART00000021369
taste receptor, type 1, member 3
chr23_+_44374041 1.31 ENSDART00000136056
eph receptor B4b
chr1_+_58094551 1.31 ENSDART00000146316
si:ch211-114l13.1
chr1_+_8110562 1.31 ENSDART00000112160
si:dkeyp-9d4.5
chr22_-_38258053 1.30 ENSDART00000132516
ELAV like neuron-specific RNA binding protein 2
chr3_+_58379450 1.29 ENSDART00000155759
short chain dehydrogenase/reductase family 42E, member 2
chr17_-_12182353 1.28 ENSDART00000153800
kinesin family member 28
chr7_-_17028015 1.28 ENSDART00000022441
developing brain homeobox 1a
chr14_-_24397718 1.28 ENSDART00000110164
si:ch211-163m17.4
chr2_+_10766744 1.28 ENSDART00000015379
growth factor independent 1A transcription repressor a
chr21_-_14773692 1.28 ENSDART00000142145
glutamate-ammonia ligase (glutamine synthase) c
chr11_+_45421761 1.28 ENSDART00000167347
HRAS-like suppressor
chr6_+_10037252 1.28 ENSDART00000018503
ENSDART00000149537
succinate-CoA ligase, ADP-forming, beta subunit
chr14_-_34771371 1.27 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
actin binding LIM protein family, member 3
chr13_-_31878043 1.27 ENSDART00000187720
synaptotagmin XIVa
chr19_+_2896188 1.27 ENSDART00000151421
si:ch211-251g8.5
chr2_+_29610114 1.26 ENSDART00000131271
discs, large (Drosophila) homolog-associated protein 1a
chr9_+_21990095 1.24 ENSDART00000146829
ENSDART00000133515
ENSDART00000193582
si:dkey-57a22.13
chr22_-_18022416 1.24 ENSDART00000141563
neurocan b
chr21_-_43094210 1.22 ENSDART00000144747
si:ch73-68b22.2
chr18_-_26675699 1.21 ENSDART00000113280
si:ch211-69m14.1
chr16_-_42969598 1.21 ENSDART00000156011
si:ch211-135n15.3
chr13_-_16257848 1.21 ENSDART00000079745
zgc:110045
chr2_+_36015049 1.20 ENSDART00000158276
laminin, gamma 2
chr4_-_72476526 1.19 ENSDART00000174153

chr16_-_41840668 1.18 ENSDART00000146150
si:dkey-199f5.4
chr10_-_8956973 1.18 ENSDART00000189564
molybdenum cofactor synthesis 2
chr12_-_19119176 1.18 ENSDART00000149180
aconitase 2, mitochondrial
chr5_-_67661102 1.17 ENSDART00000013605
zinc finger and BTB domain containing 20
chr15_+_28096152 1.17 ENSDART00000100293
ENSDART00000140092
crystallin, beta B1, like 3
chr14_-_8724290 1.17 ENSDART00000161171
Pim proto-oncogene, serine/threonine kinase, related 56
chr9_+_12896340 1.16 ENSDART00000136417
si:ch211-167j6.5
chr11_+_23265157 1.16 ENSDART00000110152
colony stimulating factor 1a (macrophage)
chr10_+_5422575 1.16 ENSDART00000063093
AU RNA binding protein/enoyl-CoA hydratase
chr5_+_19479200 1.15 ENSDART00000137703
aldehyde dehydrogenase 3 family, member B2
chr1_-_57129179 1.13 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
chr19_-_3742472 1.12 ENSDART00000162132
bloodthirsty-related gene family, member 22
chr2_-_44199722 1.12 ENSDART00000140633
ENSDART00000145728
succinate dehydrogenase complex, subunit C, integral membrane protein
chr17_+_24613255 1.11 ENSDART00000064738
ATP synthase inhibitory factor subunit 1b
chr4_-_10972912 1.11 ENSDART00000102496
si:ch211-161n3.3
chr23_+_42810055 1.10 ENSDART00000186647
myosin, light chain 9a, regulatory
chr5_-_30487822 1.10 ENSDART00000189288
ENSDART00000183201
pleckstrin homology-like domain, family B, member 1a
chr25_+_9004619 1.10 ENSDART00000189501
recombination activating gene 1
chr17_+_12730025 1.10 ENSDART00000064513
interleukin 17a/f2
chr4_+_25917915 1.10 ENSDART00000138603
vezatin, adherens junctions transmembrane protein
chr6_-_49170390 1.08 ENSDART00000182255
nerve growth factor b (beta polypeptide)
chr22_-_9157364 1.07 ENSDART00000182762
si:ch211-213a13.5
chr13_-_31878263 1.07 ENSDART00000180411
synaptotagmin XIVa
chr13_-_30645965 1.06 ENSDART00000109307
zinc finger, CCHC domain containing 24
chr5_+_58679071 1.06 ENSDART00000019561
zgc:171734
chr7_-_12464412 1.06 ENSDART00000178723
ADAMTS-like 3
chr19_-_47456787 1.05 ENSDART00000168792
transcription factor AP-2 epsilon
chr8_+_33105974 1.04 ENSDART00000137165
si:dkey-191c17.2
chr8_-_48675411 1.04 ENSDART00000165081
Pim proto-oncogene, serine/threonine kinase, related 183
chr4_-_75047192 1.04 ENSDART00000193576
LARGE xylosyl- and glucuronyltransferase 1
chr11_+_27347076 1.03 ENSDART00000173383
fibulin 2
chr9_-_22245572 1.02 ENSDART00000114943
crystallin, gamma M2d4
chr10_-_44341288 1.02 ENSDART00000166131
zinc finger, SWIM-type containing 6
chr4_-_20292821 1.02 ENSDART00000136069
ENSDART00000192504
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr9_-_22147567 1.01 ENSDART00000110941
crystallin, gamma M2d14
chr13_+_35528607 0.99 ENSDART00000075414
ENSDART00000112947
WD repeat domain 27
chr18_-_33337703 0.98 ENSDART00000019233
vomeronasal 2 receptor, x1
chr25_-_244263 0.97 ENSDART00000190224

chr9_+_52613820 0.97 ENSDART00000168753
ENSDART00000165580
ENSDART00000164769
si:ch211-241j8.2
chr11_-_3574311 0.97 ENSDART00000167064
si:dkey-33m11.7
chr13_-_11671690 0.96 ENSDART00000179592

chr17_-_24838927 0.95 ENSDART00000123259

chr21_-_17016105 0.94 ENSDART00000189120

chr10_-_44027391 0.94 ENSDART00000145404
crystallin, beta B1

Network of associatons between targets according to the STRING database.

First level regulatory network of thraa+thrab

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0097264 self proteolysis(GO:0097264)
1.5 7.3 GO:0003210 cardiac atrium formation(GO:0003210)
0.9 5.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.6 1.8 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.6 1.7 GO:0061317 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.5 1.6 GO:0060688 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.4 12.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.4 2.9 GO:0090497 mesenchymal cell migration(GO:0090497)
0.4 1.9 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.4 1.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.4 2.2 GO:0006574 valine catabolic process(GO:0006574)
0.4 1.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.4 2.2 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.3 1.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.3 1.6 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.3 3.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.3 1.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 1.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3 0.8 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.3 1.3 GO:0033273 response to vitamin(GO:0033273)
0.2 1.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2 1.6 GO:0030728 ovulation(GO:0030728)
0.2 2.0 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 1.4 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.2 1.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 1.8 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.2 3.1 GO:0009437 carnitine metabolic process(GO:0009437)
0.2 2.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.6 GO:0060612 adipose tissue development(GO:0060612)
0.2 3.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 1.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.6 GO:0061032 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 17.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.0 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 0.5 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 1.3 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.3 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 2.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0016117 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 3.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.1 GO:0033151 V(D)J recombination(GO:0033151)
0.1 2.0 GO:0021984 adenohypophysis development(GO:0021984)
0.1 2.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 2.0 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 2.6 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:0048242 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.5 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 2.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.7 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 0.8 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.4 GO:0006953 acute-phase response(GO:0006953)
0.1 1.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 2.3 GO:0042476 odontogenesis(GO:0042476)
0.1 1.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.0 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 0.3 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 3.6 GO:0007602 phototransduction(GO:0007602)
0.1 1.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 1.0 GO:0046549 retinal cone cell development(GO:0046549)
0.1 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.7 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 3.7 GO:0010842 retina layer formation(GO:0010842)
0.1 2.1 GO:0043409 negative regulation of MAPK cascade(GO:0043409)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 5.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.9 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.1 1.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.7 GO:0006265 DNA topological change(GO:0006265)
0.1 0.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 1.5 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 2.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 1.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 10.8 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.4 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 4.9 GO:0006936 muscle contraction(GO:0006936)
0.0 1.2 GO:0043113 receptor clustering(GO:0043113)
0.0 2.1 GO:0003341 cilium movement(GO:0003341)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.3 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 1.3 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 1.3 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.0 GO:0000256 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
0.0 3.8 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0072178 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.0 0.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.8 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.7 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.9 GO:0006260 DNA replication(GO:0006260)
0.0 1.5 GO:0006364 rRNA processing(GO:0006364)
0.0 1.5 GO:0055001 muscle cell development(GO:0055001)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.4 1.3 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.3 2.1 GO:0036156 inner dynein arm(GO:0036156)
0.3 1.1 GO:0097519 DNA recombinase complex(GO:0097519)
0.2 5.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 1.8 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.2 1.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 1.0 GO:0000801 central element(GO:0000801)
0.2 6.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.2 16.2 GO:0030018 Z disc(GO:0030018)
0.2 3.7 GO:0046930 pore complex(GO:0046930)
0.1 2.0 GO:0030056 hemidesmosome(GO:0030056)
0.1 11.5 GO:0005882 intermediate filament(GO:0005882)
0.1 6.4 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 3.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.0 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 3.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 4.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 6.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 2.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891) calcium channel complex(GO:0034704)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.3 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0015288 porin activity(GO:0015288)
0.7 7.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.6 2.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.5 1.4 GO:0005499 vitamin D binding(GO:0005499)
0.4 3.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 1.3 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.4 1.2 GO:0003994 aconitate hydratase activity(GO:0003994)
0.4 2.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 1.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.4 1.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.4 5.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 1.6 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.3 1.3 GO:0033149 FFAT motif binding(GO:0033149)
0.3 2.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 1.1 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.3 1.9 GO:0004984 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.3 19.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.0 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.2 1.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 1.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 5.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 3.4 GO:0005123 death receptor binding(GO:0005123)
0.2 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 1.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 2.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 1.3 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 3.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 1.3 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 5.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.0 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 1.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 2.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 4.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.7 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 1.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.4 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 1.0 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 1.5 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 2.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 3.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.3 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 1.9 GO:0005518 collagen binding(GO:0005518)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 3.1 GO:0005178 integrin binding(GO:0005178)
0.1 1.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 2.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 30.4 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 2.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 2.4 GO:0015293 symporter activity(GO:0015293)
0.0 2.5 GO:0005125 cytokine activity(GO:0005125)
0.0 4.4 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 10.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.2 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.1 PID AURORA B PATHWAY Aurora B signaling
0.1 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 1.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 3.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 1.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 1.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 3.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 2.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor