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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for vax2

Z-value: 0.51

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Transcription factors associated with vax2

Gene Symbol Gene ID Gene Info
ENSDARG00000058702 ventral anterior homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
vax2dr11_v1_chr7_-_8881514_88815140.037.9e-01Click!

Activity profile of vax2 motif

Sorted Z-values of vax2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_29160102 8.68 ENSDART00000162854
pyruvate kinase M1/2b
chr6_-_46941245 7.77 ENSDART00000037875
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 1
chr5_+_37903790 4.43 ENSDART00000162470
transmembrane protease, serine 4b
chr12_+_3078221 3.76 ENSDART00000148835
ENSDART00000149427
sarcoglycan, alpha
chr10_-_34002185 3.11 ENSDART00000046599
zygote arrest 1-like
chr6_-_46861676 3.05 ENSDART00000188712
ENSDART00000190148
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr11_-_2131280 2.60 ENSDART00000008409
calcium binding and coiled-coil domain 1b
chr12_-_33357655 2.54 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr11_-_44801968 2.27 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr13_-_37229245 2.18 ENSDART00000140923
si:dkeyp-77c8.5
chr14_-_858985 1.98 ENSDART00000148687
ENSDART00000149375
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr5_-_68093169 1.97 ENSDART00000051849
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr14_+_5385855 1.80 ENSDART00000031508
ladybird homeobox 2
chr14_+_45406299 1.76 ENSDART00000173142
ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr11_-_6452444 1.72 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
La ribonucleoprotein domain family, member 6b
chr16_-_42056137 1.70 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr2_+_6253246 1.60 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr15_-_33925851 1.55 ENSDART00000187807
ENSDART00000187780
myelin associated glycoprotein
chr18_-_40708537 1.54 ENSDART00000077577
si:ch211-132b12.8
chr13_+_38817871 1.53 ENSDART00000187708
collagen, type XIX, alpha 1
chr17_-_49978986 1.46 ENSDART00000154728
collagen, type XII, alpha 1a
chr7_+_42461850 1.45 ENSDART00000190350
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr8_+_30664077 1.38 ENSDART00000138750
adenosine A2a receptor a
chr14_-_34771371 1.26 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
actin binding LIM protein family, member 3
chr21_+_31150438 1.26 ENSDART00000065366
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr10_+_42423318 1.25 ENSDART00000134282
neuropeptide Y receptor Y8a
chr6_-_7726849 1.23 ENSDART00000151511
solute carrier family 25, member 38b
chr19_+_5480327 1.17 ENSDART00000148794
junction plakoglobin b
chr18_+_34225520 1.16 ENSDART00000126115
vomeronasal 2 receptor, l1
chr13_-_35808904 1.15 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr1_-_55248496 1.11 ENSDART00000098615
nanos homolog 3
chr15_+_34988148 1.09 ENSDART00000076269
coiled-coil domain containing 105
chr9_-_43538328 1.08 ENSDART00000140526
zinc finger protein 385B
chr1_+_19303241 1.07 ENSDART00000129970
si:dkeyp-118a3.2
chr6_+_7421898 1.06 ENSDART00000043946
coiled-coil domain containing 65
chr18_+_27821856 1.00 ENSDART00000131712
si:ch211-222m18.4
chr8_-_53044300 0.99 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr21_+_42930558 0.99 ENSDART00000135234
serine/threonine kinase 32A
chr1_-_33351780 0.94 ENSDART00000178996
glycogenin 2
chr16_+_13818500 0.93 ENSDART00000135245
folliculin
chr1_+_21731382 0.93 ENSDART00000054395
paired box 5
chr16_-_32837806 0.90 ENSDART00000003997
si:dkey-165n16.5
chr8_+_45186989 0.89 ENSDART00000143861
si:ch211-220m6.4
chr4_-_58978527 0.89 ENSDART00000150408
si:ch211-64i20.5_2
chr25_+_10913725 0.89 ENSDART00000153472
major histocompatibility complex class I LJA
chr21_+_31150773 0.88 ENSDART00000126205
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr23_+_4709607 0.88 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr22_-_209741 0.88 ENSDART00000171954
olfactory receptor class A related 1
chr22_+_7738966 0.88 ENSDART00000147073
si:ch73-44m9.5
chr16_-_15387459 0.87 ENSDART00000053754
hyaluronan synthase 2
chr14_-_4556896 0.85 ENSDART00000044678
ENSDART00000192863
gamma-aminobutyric acid type A receptor alpha2 subunit
chr7_+_54642005 0.85 ENSDART00000171864
fibroblast growth factor 19
chr21_-_31290582 0.83 ENSDART00000065362
carbonic anhydrase IV c
chr15_-_35134918 0.82 ENSDART00000157196
si:ch211-272b8.7
chr14_-_8724290 0.80 ENSDART00000161171
Pim proto-oncogene, serine/threonine kinase, related 56
chr8_+_28695914 0.80 ENSDART00000033386
osteoclast stimulatory transmembrane protein
chr4_+_44954486 0.79 ENSDART00000150875
si:dkeyp-100h4.8
chr16_-_11798994 0.78 ENSDART00000135408
cornifelin
chr25_-_13490744 0.78 ENSDART00000056721
lactate dehydrogenase D
chr17_+_8799661 0.77 ENSDART00000105326
tonsoku-like, DNA repair protein
chr15_-_4528326 0.77 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr1_+_49668423 0.76 ENSDART00000150880
testis specific, 10
chr2_+_53204750 0.75 ENSDART00000163644
zgc:165603
chr23_+_30827959 0.74 ENSDART00000033429
neuropeptides B/W receptor 2a
chr13_-_38039871 0.73 ENSDART00000140645

chr13_+_255067 0.71 ENSDART00000102505
forkhead box G1d
chr7_-_12464412 0.70 ENSDART00000178723
ADAMTS-like 3
chr23_+_238893 0.70 ENSDART00000138198
si:ch73-162j3.4
chr21_+_32820175 0.68 ENSDART00000076903
adrenergic, alpha-2D-, receptor b
chr11_-_2838699 0.68 ENSDART00000066189
LHFPL tetraspan subfamily member 5a
chr20_+_28861629 0.68 ENSDART00000187274
ENSDART00000047826
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr6_-_59942335 0.66 ENSDART00000168416
F-box and leucine-rich repeat protein 3b
chr11_+_705727 0.63 ENSDART00000165366
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr4_-_13548806 0.62 ENSDART00000067155
interleukin 22
chr6_+_27151940 0.61 ENSDART00000088364
kinesin family member 1Aa
chr13_-_36798204 0.61 ENSDART00000012357
salvador family WW domain containing protein 1
chr20_-_43663494 0.61 ENSDART00000144564

chr2_+_10007113 0.61 ENSDART00000155213
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr14_-_30587814 0.61 ENSDART00000144912
ENSDART00000149714
transmembrane protein 265
chr1_-_19502322 0.60 ENSDART00000181888
ENSDART00000044030
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr24_+_26134209 0.60 ENSDART00000038824
teleost multiple tissue opsin b
chr20_-_28800999 0.59 ENSDART00000049462
RAB15, member RAS oncogene family
chr2_-_9818640 0.59 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
adaptor-related protein complex 2, mu 1 subunit, b
chr4_-_2975461 0.57 ENSDART00000150794
pleckstrin homology domain containing, family A member 5
chr10_+_38560032 0.57 ENSDART00000177197

chr15_+_45640906 0.54 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr12_+_47698356 0.54 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr12_+_48803098 0.52 ENSDART00000074768
peptidylprolyl isomerase Fb
chr3_-_34034498 0.52 ENSDART00000151145
immunoglobulin heavy variable 11-2
chr11_-_2478374 0.51 ENSDART00000173205
si:ch73-267c23.10
chr22_+_18477934 0.50 ENSDART00000132684
cartilage intermediate layer protein 2
chr15_+_31303355 0.50 ENSDART00000143423
odorant receptor, family F, subfamily 116, member 2
chr7_-_60156409 0.50 ENSDART00000006802
chaperonin containing TCP1, subunit 7 (eta)
chr10_+_16584382 0.48 ENSDART00000112039

chr2_+_22808946 0.48 ENSDART00000133250
autoimmune regulator
chr17_+_3379673 0.46 ENSDART00000176354
syntrophin, gamma 2
chr17_-_10122204 0.46 ENSDART00000160751

chr13_+_40501455 0.46 ENSDART00000114985
heparanase 2
chr16_+_31804590 0.45 ENSDART00000167321
wingless-type MMTV integration site family, member 4b
chr8_+_49778486 0.45 ENSDART00000131732
neurotrophic tyrosine kinase, receptor, type 2a
chr24_+_37640626 0.43 ENSDART00000008047
WD repeat domain 24
chr8_+_16025554 0.43 ENSDART00000110171
ELAV like neuron-specific RNA binding protein 4
chr14_+_29941445 0.41 ENSDART00000181761
family with sequence similarity 149 member A
chr4_+_966061 0.41 ENSDART00000122535
RNA polymerase II associated protein 3
chr13_-_29420885 0.39 ENSDART00000024225
choline O-acetyltransferase a
chr20_-_7133546 0.39 ENSDART00000160910
si:ch211-121a2.4
chr1_-_15797663 0.38 ENSDART00000177122
sarcoglycan zeta
chr18_+_28106139 0.38 ENSDART00000089615
KIAA1549-like b
chr4_+_9400012 0.38 ENSDART00000191960
transmembrane and tetratricopeptide repeat containing 1
chr1_-_17715493 0.37 ENSDART00000133027
si:dkey-256e7.8
chr19_+_3213914 0.35 ENSDART00000193144
zgc:86598
chr11_+_31864921 0.34 ENSDART00000180252
diaphanous-related formin 3
chr11_-_40728380 0.34 ENSDART00000023745
coiled-coil domain containing 114
chr4_+_77943184 0.34 ENSDART00000159094
protein kinase C and casein kinase substrate in neurons 2
chr6_+_24398907 0.33 ENSDART00000167482
transforming growth factor, beta receptor III
chr21_-_13972745 0.33 ENSDART00000143874
AT-hook transcription factor
chrM_+_12897 0.32 ENSDART00000093622
NADH dehydrogenase 5, mitochondrial
chr20_-_9278252 0.32 ENSDART00000136079
synaptotagmin XIVb
chr17_-_200316 0.32 ENSDART00000190561

chr20_+_28861435 0.30 ENSDART00000142678
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr5_-_51619742 0.29 ENSDART00000188537
orthopedia homeobox b
chr3_+_17537352 0.26 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr10_+_11261576 0.26 ENSDART00000155333
hydroxysteroid dehydrogenase like 2
chr15_-_22074315 0.26 ENSDART00000149830
dopamine receptor D2a
chr23_-_15216654 0.25 ENSDART00000131649
sulfatase 2b
chr10_-_2788668 0.24 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2 (absent, small, or homeotic)-like (Drosophila)
chr8_+_23738122 0.24 ENSDART00000062983
ribosomal protein L10a
chr9_-_34937025 0.24 ENSDART00000137888
cell division cycle 16 homolog (S. cerevisiae)
chr11_+_33312601 0.24 ENSDART00000188024
contactin associated protein-like 5 like
chr2_+_105748 0.23 ENSDART00000169601

chr12_+_20587179 0.23 ENSDART00000170127
arylsulfatase G
chr3_-_21280373 0.22 ENSDART00000003939
synaptogyrin 1a
chr2_+_50608099 0.19 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr14_+_40874608 0.19 ENSDART00000168448
si:ch211-106m9.1
chr22_+_23359369 0.18 ENSDART00000170886
DENN/MADD domain containing 1B
chr24_-_37640705 0.17 ENSDART00000066583
zgc:112496
chr4_-_48957129 0.17 ENSDART00000150426
zinc finger protein 1064
chr11_-_42554290 0.16 ENSDART00000130573
ATPase H+ transporting accessory protein 1 like a
chr7_-_30174882 0.16 ENSDART00000110409
FERM domain containing 5
chr2_+_53720028 0.16 ENSDART00000170799
catenin, beta like 1
chr24_+_12894282 0.12 ENSDART00000061301
si:dkeyp-28d2.4
chr5_-_16472719 0.12 ENSDART00000162071
piwi-like RNA-mediated gene silencing 2
chr16_-_20932896 0.12 ENSDART00000180646
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr17_+_30369107 0.10 ENSDART00000182286
ENSDART00000139091
growth regulation by estrogen in breast cancer 1
chr23_-_2901167 0.09 ENSDART00000165955
ENSDART00000190616
zinc fingers and homeoboxes 3
chr23_-_35790235 0.09 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
major facilitator superfamily domain containing 5
chr20_-_9095105 0.08 ENSDART00000140792
OMA1 zinc metallopeptidase
chr16_+_13818743 0.07 ENSDART00000090191
folliculin
chr8_-_53680653 0.05 ENSDART00000164739
wingless-type MMTV integration site family, member 5a
chr23_+_2906031 0.05 ENSDART00000109304
c23h20orf24 homolog (H. sapiens)
chr8_+_18011522 0.05 ENSDART00000136756
single stranded DNA binding protein 3b
chr8_+_2543525 0.04 ENSDART00000129569
ENSDART00000128227
GLE1 RNA export mediator homolog (yeast)
chr9_-_44295071 0.03 ENSDART00000011837
neuronal differentiation 1
chr8_+_23521974 0.03 ENSDART00000188130
ENSDART00000129378
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr4_-_30422325 0.02 ENSDART00000158444
zinc finger protein 1114
chr7_+_9873750 0.01 ENSDART00000173348
ENSDART00000172813
lines homolog 1
chr10_-_11261386 0.01 ENSDART00000189946
polypyrimidine tract binding protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of vax2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.4 2.0 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.4 1.8 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.3 1.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 2.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.3 1.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 0.9 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 0.8 GO:0006089 lactate metabolic process(GO:0006089)
0.2 1.2 GO:0002159 desmosome assembly(GO:0002159)
0.2 4.0 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 3.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.5 GO:0032602 chemokine production(GO:0032602) negative T cell selection(GO:0043383) thymocyte migration(GO:0072679)
0.2 0.6 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.4 GO:1990416 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.0 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 1.1 GO:0003352 regulation of cilium movement(GO:0003352)
0.1 0.7 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 8.7 GO:0006096 glycolytic process(GO:0006096)
0.1 0.4 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.9 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 2.2 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.3 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 0.9 GO:0007608 sensory perception of smell(GO:0007608)
0.1 1.5 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 1.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0042755 eating behavior(GO:0042755)
0.1 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0021767 mammillary body development(GO:0021767)
0.0 0.5 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.5 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.6 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 2.6 GO:0006414 translational elongation(GO:0006414)
0.0 2.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.8 GO:0031297 replication fork processing(GO:0031297)
0.0 0.5 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.3 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.3 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.7 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 2.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.6 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.0 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 2.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 4.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.0 GO:0005903 brush border(GO:0005903)
0.1 1.2 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.2 GO:0043186 P granule(GO:0043186)
0.0 0.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 8.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.4 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.5 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 2.0 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.3 2.0 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.3 0.9 GO:0072545 tyrosine binding(GO:0072545)
0.3 0.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 2.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 2.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 3.3 GO:0032190 acrosin binding(GO:0032190)
0.2 1.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 1.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.8 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 1.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.6 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.7 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 4.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 2.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 4.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 4.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 2.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase