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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for zbtb49

Z-value: 0.39

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Transcription factors associated with zbtb49

Gene Symbol Gene ID Gene Info
zbtb49
ENSDARG00000102111 zinc finger and BTB domain containing 49

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb49dr11_v1_chr14_-_30050_30050-0.028.6e-01Click!

Activity profile of zbtb49 motif

Sorted Z-values of zbtb49 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_22823889 5.09 ENSDART00000127467
ENSDART00000148576
ENSDART00000149993
pygmb
phosphorylase, glycogen, muscle b
chr1_-_38709551 3.80 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr20_-_10120442 3.33 ENSDART00000144970
meis2b
Meis homeobox 2b
chr24_-_3419998 3.29 ENSDART00000066839
slc35g2b
solute carrier family 35, member G2b
chr12_+_26632448 2.97 ENSDART00000185762
arhgap12b
Rho GTPase activating protein 12b
chr21_+_25181003 2.88 ENSDART00000169700
si:dkey-183i3.9
si:dkey-183i3.9
chr7_-_52334840 2.69 ENSDART00000174173
CR938716.1

chr7_-_38340674 2.29 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr8_+_25302172 1.85 ENSDART00000046182
ENSDART00000145316
gstm.3
glutathione S-transferase mu tandem duplicate 3
chr22_+_12798569 1.84 ENSDART00000005720
stat1a
signal transducer and activator of transcription 1a
chr7_-_31941670 1.83 ENSDART00000180929
ENSDART00000075389
bdnf
brain-derived neurotrophic factor
chr8_-_38477817 1.70 ENSDART00000075989
inpp5l
inositol polyphosphate-5-phosphatase L
chr14_+_33882973 1.64 ENSDART00000019396
clic2
chloride intracellular channel 2
chr9_+_8942258 1.61 ENSDART00000138836
ankrd10b
ankyrin repeat domain 10b
chr14_-_49896795 1.34 ENSDART00000168142
ube2d2l
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like
chr9_+_38629962 1.26 ENSDART00000184890
znf148
zinc finger protein 148
chr10_-_15919839 1.08 ENSDART00000065032
pip5k1ba
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr9_+_14152211 0.98 ENSDART00000148055
si:ch211-67e16.11
si:ch211-67e16.11
chr13_-_2283176 0.97 ENSDART00000158462
lrrc1
leucine rich repeat containing 1
chr17_+_8925232 0.71 ENSDART00000036668
psmc1a
proteasome 26S subunit, ATPase 1a
chr8_+_36582728 0.70 ENSDART00000049230
pqbp1
polyglutamine binding protein 1
chr7_-_44794322 0.62 ENSDART00000019270
nae1
nedd8 activating enzyme E1 subunit 1
chr6_-_55399214 0.46 ENSDART00000168367
ctsa
cathepsin A
chr21_-_22676323 0.39 ENSDART00000167392
gig2h
grass carp reovirus (GCRV)-induced gene 2h
chr13_+_51853716 0.33 ENSDART00000175341
ENSDART00000187855
LT631684.1

chr22_+_10158502 0.31 ENSDART00000005869
rpp14
ribonuclease P/MRP 14 subunit
chr15_-_2734560 0.25 ENSDART00000153853
ppp5c
protein phosphatase 5, catalytic subunit
chr11_+_8565323 0.21 ENSDART00000081607
ENSDART00000141612
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr9_+_29430432 0.19 ENSDART00000125632
uggt2
UDP-glucose glycoprotein glucosyltransferase 2
chr8_+_36582915 0.12 ENSDART00000139482
pqbp1
polyglutamine binding protein 1
chr17_+_25590127 0.09 ENSDART00000064803
iars2
isoleucyl-tRNA synthetase 2, mitochondrial
chr11_+_8565828 0.01 ENSDART00000126523
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb49

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.8 2.3 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.3 3.3 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.2 3.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.8 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 1.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.7 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 1.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 1.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.6 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.6 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.2 1.7 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 0.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.4 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 2.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.6 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 1.1 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.8 GO:0043021 ribonucleoprotein complex binding(GO:0043021)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle