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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for zbtb7b

Z-value: 0.54

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Transcription factors associated with zbtb7b

Gene Symbol Gene ID Gene Info
ENSDARG00000021891 zinc finger and BTB domain containing 7B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb7bdr11_v1_chr16_-_54810464_54810464-0.047.0e-01Click!

Activity profile of zbtb7b motif

Sorted Z-values of zbtb7b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_77557279 10.38 ENSDART00000180113

chr4_+_55758103 10.24 ENSDART00000185964

chr4_-_77551860 7.67 ENSDART00000188176

chr4_-_77563411 6.90 ENSDART00000186841

chr19_+_48117995 6.11 ENSDART00000170865
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr9_-_39005317 5.15 ENSDART00000014207
myosin, light chain 1, alkali; skeletal, fast
chr4_-_68569527 4.93 ENSDART00000192091

chr22_-_188102 4.86 ENSDART00000125391
ENSDART00000170463

chr3_+_18399315 3.97 ENSDART00000110842
ribosomal protein S2
chr20_-_21672970 3.95 ENSDART00000133286
si:ch211-207i1.2
chr16_+_29650698 3.92 ENSDART00000137153
tropomodulin 4 (muscle)
chr20_-_487783 3.66 ENSDART00000162218
collagen, type X, alpha 1b
chr22_-_7050 3.61 ENSDART00000127829
ATPase family, AAA domain containing 3
chr21_-_233282 3.50 ENSDART00000157684
brix domain containing 2
chr19_-_47555956 3.38 ENSDART00000114549
actin, alpha, cardiac muscle 1a
chr21_-_11646878 3.38 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr21_+_233271 3.36 ENSDART00000171440
DTW domain containing 2
chr5_-_69621227 3.33 ENSDART00000178543
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr1_-_59216197 3.27 ENSDART00000062426
lysophosphatidic acid receptor 2b
chr5_-_16351306 3.21 ENSDART00000168643

chr20_-_29483514 3.16 ENSDART00000062370
actin, alpha, cardiac muscle 1a
chr23_-_44848961 3.10 ENSDART00000136839
wu:fb72h05
chr6_+_36821621 2.99 ENSDART00000104157
transmembrane protein 45a
chr1_+_51475094 2.90 ENSDART00000146352
Meis homeobox 1 a
chr23_+_36101185 2.90 ENSDART00000103139
homeobox C8a
chr4_-_2380173 2.89 ENSDART00000177727
nucleosome assembly protein 1-like 1
chr6_-_43677125 2.89 ENSDART00000150128
forkhead box P1b
chr9_-_8314028 2.85 ENSDART00000102739
si:ch211-145c1.1
chr18_-_26715655 2.80 ENSDART00000181497
MALT paracaspase 3
chr24_-_38110779 2.77 ENSDART00000147783
c-reactive protein, pentraxin-related
chr1_+_15062 2.75 ENSDART00000169005
centrosomal protein 97
chr21_-_45086170 2.72 ENSDART00000188963
Rap guanine nucleotide exchange factor (GEF) 6
chr1_-_44638058 2.72 ENSDART00000081835
solute carrier family 43 (amino acid system L transporter), member 1b
chr19_-_11237125 2.71 ENSDART00000163921
signal sequence receptor, beta
chr12_+_48841419 2.69 ENSDART00000125331
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr21_+_28747236 2.62 ENSDART00000137874
zgc:100829
chr3_+_2669813 2.60 ENSDART00000014205

chr20_+_33875256 2.54 ENSDART00000002554
retinoid X receptor, gamma b
chr22_-_17729778 2.53 ENSDART00000192132
si:ch73-63e15.2
chr17_+_52524452 2.49 ENSDART00000016614
dihydrolipoamide S-succinyltransferase
chr6_+_28203 2.46 ENSDART00000191561

chr20_+_39250673 2.43 ENSDART00000153003
RALBP1 associated Eps domain containing 1
chr22_-_24900121 2.22 ENSDART00000147643
si:dkey-4c23.3
chr18_-_8030073 2.21 ENSDART00000151490
SH3 and multiple ankyrin repeat domains 3a
chr7_+_39401388 2.20 ENSDART00000144750
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr6_+_3334710 2.16 ENSDART00000132848
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr13_-_51922290 2.13 ENSDART00000168648
serum response factor b
chr14_-_9522364 2.13 ENSDART00000054689
atonal bHLH transcription factor 8
chr11_-_497680 2.12 ENSDART00000154888
CCHC-type zinc finger, nucleic acid binding protein b
chr12_-_4540564 2.11 ENSDART00000106566

chr21_-_28901095 2.10 ENSDART00000180820
CXXC finger protein 5a
chr8_-_53488832 2.08 ENSDART00000191801
choline dehydrogenase
chr17_-_4395373 2.06 ENSDART00000015923
kelch-like family member 10a
chr21_-_32684570 1.97 ENSDART00000162873
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr18_-_41161828 1.96 ENSDART00000114993

chr14_+_40685469 1.95 ENSDART00000172839
tenomodulin
chr25_-_34284144 1.92 ENSDART00000188109
glucosaminyl (N-acetyl) transferase 3, mucin type
chr3_-_29891456 1.88 ENSDART00000151677
ENSDART00000014021
solute carrier family 25, member 39
chr3_-_4501026 1.85 ENSDART00000163052
zgc:162198
chr2_+_24781026 1.84 ENSDART00000145692
phosphodiesterase 4C, cAMP-specific a
chr2_+_29884363 1.83 ENSDART00000139247
si:ch211-207d6.2
chr6_-_10788065 1.82 ENSDART00000190968
WAS/WASL interacting protein family, member 1b
chr12_-_990149 1.80 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr24_+_42131564 1.79 ENSDART00000153854
WW domain containing E3 ubiquitin protein ligase 1
chr6_-_8489810 1.72 ENSDART00000124643
RAS protein activator like 3
chr16_+_16826504 1.70 ENSDART00000108691
potassium inwardly-rectifying channel, subfamily J, member 14
chr1_+_594736 1.70 ENSDART00000166731
junctional adhesion molecule 2a
chr4_+_1530287 1.70 ENSDART00000067446
solute carrier family 38, member 4
chr6_+_3334392 1.69 ENSDART00000133707
ENSDART00000130879
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr6_-_10791880 1.66 ENSDART00000104884
WAS/WASL interacting protein family, member 1b
chr7_-_5070794 1.65 ENSDART00000097877
leukotriene B4 receptor 2a
chr21_-_45871866 1.64 ENSDART00000161716
La ribonucleoprotein domain family, member 1
chr21_+_11244068 1.62 ENSDART00000163432
AT-rich interaction domain 6
chr18_-_26715156 1.62 ENSDART00000142043
MALT paracaspase 3
chr12_+_10443785 1.59 ENSDART00000029133
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr21_+_28747069 1.59 ENSDART00000014058
zgc:100829
chr1_+_59538755 1.55 ENSDART00000166354
Sp6 transcription factor
chr19_+_41173386 1.54 ENSDART00000142773
ankyrin repeat and SOCS box containing 4
chr13_+_45582391 1.52 ENSDART00000058093
low density lipoprotein receptor adaptor protein 1b
chr4_+_57093908 1.52 ENSDART00000170198
si:ch211-238e22.5
chr13_+_41022502 1.49 ENSDART00000026808
dickkopf WNT signaling pathway inhibitor 1a
chr22_-_367569 1.49 ENSDART00000041895
SSU72 homolog, RNA polymerase II CTD phosphatase
chr8_-_52938439 1.48 ENSDART00000168185
nuclear receptor subfamily 6, group A, member 1a
chr1_+_44196236 1.47 ENSDART00000179560
ENSDART00000166324
catenin (cadherin-associated protein), delta 1
chr24_-_11467004 1.46 ENSDART00000144316
PX domain containing 1b
chr16_-_54405037 1.46 ENSDART00000186928
odd-skipped related transciption factor 2
chr14_-_16423200 1.46 ENSDART00000108868
ENSDART00000161793
mastermind-like transcriptional coactivator 1
chr15_+_5332900 1.41 ENSDART00000167567
odorant receptor, family A, subfamily 113, member 2
chr10_-_24961310 1.37 ENSDART00000037303
si:ch211-214k5.3
chr6_-_425378 1.37 ENSDART00000192190
family with sequence similarity 83, member Fb
chr25_+_150570 1.36 ENSDART00000170892
ADAM metallopeptidase domain 10b
chr10_+_35347993 1.34 ENSDART00000131350
si:dkey-259j3.5
chr17_-_8312923 1.31 ENSDART00000064678
lefty2
chr4_-_6459863 1.29 ENSDART00000138367
forkhead box P2
chr11_-_40504170 1.27 ENSDART00000165394
si:dkeyp-61b2.1
chr7_-_57332915 1.26 ENSDART00000162653

chr3_-_8265158 1.26 ENSDART00000171310
cytochrome P450, family 2, subfamily K, polypeptide 6
chr13_-_25198025 1.26 ENSDART00000159585
ENSDART00000144227
adenosine kinase a
chr6_-_53326421 1.25 ENSDART00000191740
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr22_-_506522 1.25 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr17_+_26965351 1.24 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr11_-_11878099 1.19 ENSDART00000188314
WAS/WASL interacting protein family, member 2a
chr25_+_25464630 1.19 ENSDART00000150537
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr11_-_19501439 1.18 ENSDART00000158328
ENSDART00000103983
solute carrier family 2 (facilitated glucose transporter), member 9-like 1
chr2_+_258698 1.18 ENSDART00000181330
ENSDART00000181645
PH domain and leucine rich repeat protein phosphatase 1
chr23_+_45611980 1.16 ENSDART00000181582
doublecortin-like kinase 2b
chr8_+_6954984 1.16 ENSDART00000145610
si:ch211-255g12.6
chr3_-_23643751 1.16 ENSDART00000078425
ENSDART00000140264
even-skipped-like1
chr23_+_33383583 1.16 ENSDART00000114423
Rap guanine nucleotide exchange factor (GEF) 3
chr21_+_13577227 1.16 ENSDART00000146283
si:dkey-248f6.3
chr9_+_51891 1.16 ENSDART00000163529
zgc:158316
chr17_+_53418445 1.15 ENSDART00000097631
solute carrier family 9 member A1b
chr11_-_21304452 1.12 ENSDART00000163008
si:dkey-85p17.3
chr1_+_29741843 1.12 ENSDART00000136066
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b
chr6_+_52918537 1.12 ENSDART00000174229
odorant receptor, family H, subfamily 137, member 1
chr1_+_594584 1.11 ENSDART00000135944
junctional adhesion molecule 2a
chr23_+_7518294 1.10 ENSDART00000081536
HCK proto-oncogene, Src family tyrosine kinase
chr10_-_5857548 1.10 ENSDART00000166933
si:ch211-281k19.2
chr15_-_47607480 1.09 ENSDART00000171605
suppressor of cytokine signaling 9
chr24_-_36593876 1.09 ENSDART00000160901

chr23_+_19182819 1.09 ENSDART00000131804
si:dkey-93l1.4
chr12_+_5530247 1.08 ENSDART00000114637
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr20_-_16972351 1.06 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
chr7_-_3860501 1.06 ENSDART00000191053
si:dkey-88n24.6
chr5_-_10012971 1.06 ENSDART00000179421

chr18_+_32780450 1.05 ENSDART00000168399
olfactory receptor C family, g7
chr9_-_704667 1.03 ENSDART00000147092
CASP8 and FADD-like apoptosis regulator b
chr22_-_1168291 1.02 ENSDART00000167724
si:ch1073-181h11.4
chr4_+_65306260 1.02 ENSDART00000167558
si:dkey-14o6.8
chr5_-_25621386 1.00 ENSDART00000051565
cytochrome P450, family 1, subfamily D, polypeptide 1
chr10_-_44026369 1.00 ENSDART00000185456
crystallin, beta B1
chr11_+_44548209 1.00 ENSDART00000181798
ENSDART00000191742
ENSDART00000168209
nidogen 1b
chr13_-_49444636 0.99 ENSDART00000136991
interferon regulatory factor 2 binding protein 2a
chr12_-_16764751 0.98 ENSDART00000113862
zgc:174154
chr19_-_6982272 0.98 ENSDART00000141913
ENSDART00000150957
zinc finger protein 384 like
chr12_-_4475890 0.97 ENSDART00000092492
si:ch211-173d10.1
chr1_+_56779495 0.97 ENSDART00000192871

chr10_+_22034477 0.97 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
nucleophosmin 1a
chr19_-_2707048 0.96 ENSDART00000166112
interleukin 6 (interferon, beta 2)
chr23_-_19140781 0.96 ENSDART00000143580
si:ch73-381f5.2
chr2_-_25120197 0.95 ENSDART00000132549
propionyl CoA carboxylase, beta polypeptide
chr25_-_35143360 0.93 ENSDART00000188033
zgc:165555
chr17_+_12075805 0.91 ENSDART00000155329
consortin, connexin sorting protein a
chr22_-_5918670 0.91 ENSDART00000141373
si:rp71-36a1.1
chr9_-_32191620 0.91 ENSDART00000139426
Pim proto-oncogene, serine/threonine kinase, related 143
chr15_+_44184367 0.89 ENSDART00000162918
ENSDART00000110060
zgc:165514
chr16_-_8613499 0.89 ENSDART00000189189
cordon-bleu WH2 repeat protein
chr8_+_8947623 0.88 ENSDART00000131215
solute carrier family 35 (UDP-galactose transporter), member 2
chr20_+_27242595 0.87 ENSDART00000149300
si:dkey-85n7.6
chr12_+_47945664 0.86 ENSDART00000189824
ENSDART00000055743
ENSDART00000188936

chr2_+_54389750 0.86 ENSDART00000189236
RAB12, member RAS oncogene family
chr2_-_23479714 0.85 ENSDART00000167291
si:ch211-14p21.3
chr14_-_48245816 0.84 ENSDART00000172452
relaxin/insulin-like family peptide receptor 1
chr7_+_34453185 0.84 ENSDART00000173875
ENSDART00000173921
ENSDART00000173995
si:cabz01009626.1
chr18_+_33570170 0.83 ENSDART00000133276
si:dkey-47k20.3
chr18_+_46151505 0.83 ENSDART00000015034
ENSDART00000141287
biliverdin reductase B
chr19_-_2318391 0.83 ENSDART00000012791
sp8 transcription factor a
chr22_+_10090673 0.80 ENSDART00000186680
si:dkey-102c8.3
chr23_+_19691146 0.76 ENSDART00000143001
si:dkey-93l1.6
chr24_+_40473032 0.75 ENSDART00000084238
ENSDART00000178508

chr3_+_25220334 0.72 ENSDART00000055440
C1q and TNF related 6a
chr15_-_23699737 0.71 ENSDART00000078311
zgc:154093
chr24_-_21914276 0.67 ENSDART00000128687
C1q and TNF related 9
chr5_-_26936861 0.67 ENSDART00000191032
HtrA serine peptidase 4
chr12_+_32020121 0.66 ENSDART00000191430

chr7_-_54677143 0.64 ENSDART00000163748
cyclin D1
chr12_+_48744016 0.63 ENSDART00000175518

chr4_-_25812329 0.62 ENSDART00000146658
transmembrane and coiled-coil domain family 3
chr25_+_4581214 0.61 ENSDART00000185552

chr16_+_7991274 0.61 ENSDART00000179704
anoctamin 10a
chr3_-_16289826 0.59 ENSDART00000131972
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr19_-_5058908 0.58 ENSDART00000130062
chromodomain helicase DNA binding protein 4a
chr5_-_71838520 0.57 ENSDART00000174396

chr6_+_52212927 0.56 ENSDART00000143458
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr17_+_23730089 0.55 ENSDART00000034913
zgc:91976
chr18_-_51015718 0.54 ENSDART00000190698

chr4_-_75505048 0.53 ENSDART00000163665
si:dkey-71l4.5
chr25_+_25172983 0.53 ENSDART00000103203
chemokine (C-C motif) ligand 35, duplicate 2
chr6_+_584632 0.52 ENSDART00000151150
zgc:92360
chr3_+_3810919 0.52 ENSDART00000056035

chr13_-_50366950 0.48 ENSDART00000098209
sirtuin 1
chr25_-_37331513 0.47 ENSDART00000111862
low density lipoprotein receptor class A domain containing 3
chr1_+_7414318 0.47 ENSDART00000127426
si:ch73-383l1.1
chr8_+_35356944 0.47 ENSDART00000143243
si:dkeyp-14d3.1
chr13_+_23214100 0.47 ENSDART00000163393
sorbin and SH3 domain containing 1
chr14_+_109016 0.41 ENSDART00000158405
glypican 2
chr17_+_23729717 0.40 ENSDART00000179026
zgc:91976
chr19_+_935565 0.39 ENSDART00000113368
ring finger protein 5
chr3_+_14388010 0.38 ENSDART00000171726
ENSDART00000165452
transmembrane protein 56b
chr7_+_36552725 0.34 ENSDART00000173682
chromodomain helicase DNA binding protein 9
chr9_-_37637179 0.31 ENSDART00000188143
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr16_-_24605969 0.30 ENSDART00000163305
ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr17_-_8976307 0.30 ENSDART00000092113
zinc finger, RAN-binding domain containing 1b
chr11_-_31146808 0.29 ENSDART00000172781
si:cabz01069582.1
chr18_-_19350792 0.29 ENSDART00000147902
multiple EGF-like-domains 11
chr16_-_34212912 0.29 ENSDART00000145017
phosphatase and actin regulator 4b
chr13_-_45523026 0.27 ENSDART00000020663
Rh blood group, D antigen
chr21_+_249970 0.26 ENSDART00000169026
Janus kinase 2a
chr6_+_23712911 0.25 ENSDART00000167795
zgc:158654
chr1_-_59571758 0.25 ENSDART00000193546
ENSDART00000167087
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb7b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.5 GO:0003272 endocardial cushion formation(GO:0003272)
0.8 2.5 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.7 2.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.7 2.1 GO:0019695 choline metabolic process(GO:0019695)
0.5 1.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.5 3.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.4 3.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 1.3 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.4 2.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.4 2.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 6.1 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.3 2.2 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.3 0.9 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 1.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 1.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.3 GO:0044209 AMP salvage(GO:0044209)
0.2 3.9 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 3.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.2 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 1.0 GO:0006953 acute-phase response(GO:0006953)
0.1 0.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 1.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 2.8 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.1 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.3 GO:0003128 heart field specification(GO:0003128)
0.1 1.2 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 1.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.5 GO:0032526 response to retinoic acid(GO:0032526)
0.1 1.3 GO:0045471 response to ethanol(GO:0045471)
0.1 0.8 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 1.5 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.1 1.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.7 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.9 GO:0006828 manganese ion transport(GO:0006828)
0.1 2.5 GO:0050727 regulation of inflammatory response(GO:0050727)
0.1 0.9 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 2.2 GO:0032355 response to estradiol(GO:0032355)
0.1 4.7 GO:0030048 actin filament-based movement(GO:0030048)
0.1 0.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 3.3 GO:0042493 response to drug(GO:0042493)
0.1 0.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 1.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 2.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 3.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.3 GO:0050975 sensory perception of touch(GO:0050975)
0.0 4.9 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.9 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 3.4 GO:0008033 tRNA processing(GO:0008033)
0.0 1.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 6.8 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 5.6 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 3.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.9 GO:0006865 amino acid transport(GO:0006865)
0.0 3.4 GO:0048793 pronephros development(GO:0048793)
0.0 1.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.5 GO:0005869 dynactin complex(GO:0005869)
0.3 1.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 2.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 3.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.8 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 6.1 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 4.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.0 4.7 GO:0005884 actin filament(GO:0005884)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0035060 brahma complex(GO:0035060)
0.0 2.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.1 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)
0.0 1.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0001726 ruffle(GO:0001726)
0.0 3.4 GO:0005730 nucleolus(GO:0005730)
0.0 1.0 GO:0005604 basement membrane(GO:0005604)
0.0 1.1 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.6 1.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.6 3.9 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.5 3.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.5 1.4 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.3 1.0 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.3 2.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 1.5 GO:0039706 co-receptor binding(GO:0039706)
0.3 2.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 1.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 3.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 1.6 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 1.9 GO:0016530 metallochaperone activity(GO:0016530)
0.2 3.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.9 GO:0071253 connexin binding(GO:0071253)
0.2 6.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 3.9 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 1.0 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 2.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.9 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 4.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 6.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 1.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.1 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 1.9 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 1.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 4.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.2 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 3.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.9 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 2.1 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 1.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 3.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 5.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 4.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 2.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.7 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.8 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events