Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for zic2a+zic2b

Z-value: 0.99

Motif logo

Transcription factors associated with zic2a+zic2b

Gene Symbol Gene ID Gene Info
ENSDARG00000015554 zic family member 2 (odd-paired homolog, Drosophila), a
ENSDARG00000037178 zic family member 2 (odd-paired homolog, Drosophila) b
ENSDARG00000112354 zic family member 2 (odd-paired homolog, Drosophila) b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zic2adr11_v1_chr9_+_31282161_312821610.472.1e-06Click!
zic2bdr11_v1_chr1_+_29858032_298580320.449.1e-06Click!

Activity profile of zic2a+zic2b motif

Sorted Z-values of zic2a+zic2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_83873 21.22 ENSDART00000162145
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr23_+_20422661 13.07 ENSDART00000144047
ENSDART00000104336
troponin C type 2 (fast)
chr12_-_49032899 10.50 ENSDART00000159356
growth hormone inducible transmembrane protein
chr15_+_29085955 9.57 ENSDART00000156799
si:ch211-137a8.4
chr12_+_47162456 9.30 ENSDART00000186272
ENSDART00000180811
ryanodine receptor 2
chr12_+_47162761 8.92 ENSDART00000192339
ENSDART00000167726
ryanodine receptor 2
chr8_+_31119548 8.88 ENSDART00000136578
synapsin I
chr19_+_23982466 8.67 ENSDART00000080673
synaptotagmin XIa
chr11_+_14147913 7.97 ENSDART00000022823
ENSDART00000154329
phospholipid phosphatase related 3b
chr21_-_42055872 7.07 ENSDART00000144767
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_-_30784198 6.40 ENSDART00000182523
ENSDART00000147355
regulator of G protein signaling 20
chr16_+_29303971 6.01 ENSDART00000087149
hyaluronan and proteoglycan link protein 2
chr6_+_36942966 6.01 ENSDART00000028895
neuronal growth regulator 1
chr3_-_62380146 5.94 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr4_+_4902392 5.56 ENSDART00000133866
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr1_+_25783801 5.29 ENSDART00000102455
guanylate cyclase 1 soluble subunit alpha 1
chr11_+_40657612 5.17 ENSDART00000183271
solute carrier family 45, member 1
chr3_-_19091024 5.05 ENSDART00000188485
ENSDART00000110554
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr4_+_10366532 4.82 ENSDART00000189901
potassium voltage-gated channel, Shal-related subfamily, member 2
chr14_+_29609245 4.76 ENSDART00000043058
si:dkey-34l15.2
chr3_-_30118856 4.71 ENSDART00000109953
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr14_+_25465346 4.56 ENSDART00000173436
si:dkey-280e21.3
chr13_-_36911118 4.30 ENSDART00000048739
tripartite motif containing 9
chr4_+_10365857 4.23 ENSDART00000138890
potassium voltage-gated channel, Shal-related subfamily, member 2
chr7_-_45076131 4.11 ENSDART00000110590
zgc:194678
chr11_+_30162407 4.11 ENSDART00000190333
ENSDART00000127502
cyclin-dependent kinase-like 5
chr25_+_19955598 4.06 ENSDART00000091547
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr2_-_30784502 4.05 ENSDART00000056735
regulator of G protein signaling 20
chr17_+_23937262 4.01 ENSDART00000113276
si:ch211-189k9.2
chr20_-_25669813 3.98 ENSDART00000153118
si:dkeyp-117h8.2
chr6_-_42073367 3.96 ENSDART00000154304
glutamate receptor, metabotropic 2a
chr20_-_915234 3.92 ENSDART00000164816
cannabinoid receptor 1
chr12_+_42436328 3.90 ENSDART00000167324
early B cell factor 3a
chr1_-_45042210 3.88 ENSDART00000073694
SMU1, DNA replication regulator and spliceosomal factor b
chr18_+_9641210 3.82 ENSDART00000182024
piccolo presynaptic cytomatrix protein b
chr11_+_41560792 3.80 ENSDART00000127292
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr19_-_28360033 3.79 ENSDART00000186994
si:dkey-261i16.5
chr3_+_32443395 3.78 ENSDART00000188447
proline rich 12b
chr11_-_4235811 3.77 ENSDART00000121716
si:ch211-236d3.4
chr13_+_3954540 3.70 ENSDART00000092646
leucine rich repeat containing 73
chr21_+_17110598 3.64 ENSDART00000101282
ENSDART00000191864
breakpoint cluster region
chr17_-_7371564 3.61 ENSDART00000060336
RAB32b, member RAS oncogene family
chr10_-_27197044 3.54 ENSDART00000137928
autism susceptibility candidate 2a
chr25_+_19947096 3.54 ENSDART00000154221
potassium voltage-gated channel, shaker-related, subfamily, member 6 a
chr19_-_26235219 3.53 ENSDART00000104008
dystrobrevin binding protein 1b
chr17_-_5769196 3.51 ENSDART00000113885
si:dkey-100n19.2
chr9_+_6082793 3.48 ENSDART00000192045
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr3_+_23669267 3.26 ENSDART00000111227
homeobox B10a
chr21_-_30415524 3.26 ENSDART00000101036
GrpE-like 2, mitochondrial
chr17_-_36929332 3.22 ENSDART00000183454
dihydropyrimidinase-like 5a
chr20_+_1996202 3.21 ENSDART00000184143

chr16_+_32559821 3.17 ENSDART00000093250
POU class 3 homeobox 2b
chr14_-_34026316 3.16 ENSDART00000186062
cytoplasmic FMR1 interacting protein 2
chr7_+_17716601 3.14 ENSDART00000173792
ENSDART00000080825
reticulon 3
chr20_+_26095530 3.14 ENSDART00000139350
spectrin repeat containing, nuclear envelope 1a
chr8_+_45294767 3.01 ENSDART00000191527
ubiquitin associated protein 2b
chr17_+_27434626 3.01 ENSDART00000052446
vestigial-like family member 2b
chr14_+_25464681 2.99 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr15_-_12229874 2.99 ENSDART00000165159
Down syndrome cell adhesion molecule like 1
chr22_-_14128716 2.99 ENSDART00000140323
si:ch211-246m6.4
chr18_+_9637744 2.99 ENSDART00000190171
piccolo presynaptic cytomatrix protein b
chr9_+_54417141 2.97 ENSDART00000056810
dopamine receptor D1b
chr4_-_2219705 2.92 ENSDART00000131046
si:ch73-278m9.1
chr17_-_42213822 2.90 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr3_-_12187245 2.87 ENSDART00000189553
ENSDART00000165131
sarcalumenin
chr15_-_26844591 2.87 ENSDART00000077582
PITPNM family member 3
chr25_-_28384954 2.76 ENSDART00000073500
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr10_+_40235959 2.66 ENSDART00000145862
GRAM domain containing 1Ba
chr9_+_24159725 2.63 ENSDART00000137756
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr21_-_45588720 2.62 ENSDART00000186642
ENSDART00000189531

chr2_+_26656283 2.57 ENSDART00000133202
ENSDART00000099208
aspartate beta-hydroxylase
chr1_+_39597809 2.49 ENSDART00000122700
teneurin transmembrane protein 3
chr14_-_40389699 2.45 ENSDART00000181581
ENSDART00000173398
protocadherin 19
chr12_+_27117609 2.36 ENSDART00000076154
homeobox B8b
chr13_-_30150592 2.32 ENSDART00000143093
secretion associated, Ras related GTPase 1Ab
chr11_-_23025949 2.29 ENSDART00000184859
ENSDART00000167818
ENSDART00000046122
ENSDART00000193120
ATPase plasma membrane Ca2+ transporting 2
chr19_+_9050852 2.27 ENSDART00000151031
ash1 (absent, small, or homeotic)-like (Drosophila)
chr25_+_26923193 2.14 ENSDART00000187364
glutamate receptor, metabotropic 8b
chr12_+_27096835 2.13 ENSDART00000149475
tubulin tyrosine ligase-like family, member 6
chr5_+_19320554 2.06 ENSDART00000165119
RUN and SH3 domain containing 2
chr22_-_24858042 2.03 ENSDART00000137998
ENSDART00000078216
ENSDART00000138378
vitellogenin 7
chr23_-_27501923 1.96 ENSDART00000188394
ankyrin repeat and SOCS box containing 8
chr14_-_29859067 1.92 ENSDART00000136380
sorbin and SH3 domain containing 2b
chr18_+_48576527 1.89 ENSDART00000167555
potassium inwardly-rectifying channel, subfamily J, member 5
chr23_+_23119008 1.84 ENSDART00000132418
sterile alpha motif domain containing 11
chr13_-_32577386 1.83 ENSDART00000016535
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr24_-_21490628 1.83 ENSDART00000181546
ATPase phospholipid transporting 8A2
chr17_-_24879003 1.75 ENSDART00000123147
zinc finger and BTB domain containing 8A
chr11_-_41130239 1.72 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr23_+_43668756 1.72 ENSDART00000112598
OTU deubiquitinase 4
chr4_-_56157199 1.68 ENSDART00000169806
si:ch211-207e19.15
chr19_-_22568203 1.66 ENSDART00000182888
plectin a
chr5_-_58112032 1.66 ENSDART00000016418
dopamine receptor D2b
chr2_+_35615547 1.63 ENSDART00000135843
ankyrin repeat domain 45
chr1_-_58880613 1.62 ENSDART00000188136

chr9_-_20372977 1.62 ENSDART00000113418
immunoglobulin superfamily, member 3
chr22_-_7809904 1.60 ENSDART00000182269
ENSDART00000097201
ENSDART00000138522
si:ch73-44m9.3
si:ch73-44m9.1
chr25_-_18778356 1.54 ENSDART00000111425
F-box and leucine-rich repeat protein 13
chr8_-_52859301 1.53 ENSDART00000162004
nuclear receptor subfamily 5, group A, member 1a
chr5_-_13835461 1.51 ENSDART00000148297
ENSDART00000114841
adducin 2 (beta)
chr8_-_18316482 1.46 ENSDART00000190156
ring finger protein 220b
chr11_+_3006124 1.45 ENSDART00000126071
copine Vb
chr13_+_24280380 1.44 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr4_+_21741228 1.43 ENSDART00000112035
ENSDART00000127664
myogenic factor 5
chr3_-_25814097 1.42 ENSDART00000169706
netrin 1b
chr20_+_54349333 1.38 ENSDART00000132168
ENSDART00000147542
zinc finger protein 410
chr22_+_28818291 1.36 ENSDART00000136032
tumor protein p53 binding protein, 2b
chr5_+_17727310 1.36 ENSDART00000147657
fibrosin-like 1
chr6_+_27090800 1.35 ENSDART00000121558
autophagy related 4B, cysteine peptidase
chr21_+_39963851 1.35 ENSDART00000144435
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr10_+_2876378 1.35 ENSDART00000192083
cell cycle and apoptosis regulator 2
chr22_-_24818066 1.34 ENSDART00000143443
vitellogenin 6
chr3_-_37351225 1.34 ENSDART00000174685
si:ch211-278a6.1
chr17_-_34952562 1.27 ENSDART00000021128
kinase D-interacting substrate 220a
chr17_-_6349044 1.25 ENSDART00000081707
organic cation transporter 2
chr20_+_25350435 1.25 ENSDART00000063034
family with sequence similarity 228, member A
chr11_-_38554394 1.23 ENSDART00000102858
nuclear casein kinase and cyclin-dependent kinase substrate 1a
chr18_+_17827149 1.22 ENSDART00000190237
ENSDART00000189345
si:ch211-216l23.1
chr8_-_25817106 1.20 ENSDART00000099364
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr20_-_28642061 1.20 ENSDART00000135513
regulator of G protein signaling 6
chr9_-_46072805 1.17 ENSDART00000169682
histone deacetylase 4
chr22_-_37611681 1.17 ENSDART00000028085
tetratricopeptide repeat domain 14
chr10_-_13116337 1.14 ENSDART00000164568
muscle, skeletal, receptor tyrosine kinase
chr10_+_43188678 1.13 ENSDART00000012522
versican b
chr9_+_8372167 1.12 ENSDART00000181945
ENSDART00000146122
si:dkey-90l23.1
chr16_+_48729947 1.12 ENSDART00000049051
bromodomain containing 2b
chr5_-_30151815 1.12 ENSDART00000156048
zinc finger and BTB domain containing 44
chr6_-_10693111 1.11 ENSDART00000187206
ENSDART00000192319
dynein, axonemal, heavy polypeptide 9 like
chr24_+_28410651 1.10 ENSDART00000192666

chrM_+_4993 1.10 ENSDART00000093600
NADH dehydrogenase 2, mitochondrial
chr4_+_37503994 1.10 ENSDART00000158217
zinc finger protein 1102
chr8_+_35356944 1.09 ENSDART00000143243
si:dkeyp-14d3.1
chr3_+_2669813 1.03 ENSDART00000014205

chr9_+_14152211 1.02 ENSDART00000148055
si:ch211-67e16.11
chr10_-_40448736 1.02 ENSDART00000137644
ENSDART00000168190
trace amine associated receptor 20p
chr21_-_5856050 1.02 ENSDART00000115367

chr17_+_5426087 1.01 ENSDART00000131430
ENSDART00000188636
runt-related transcription factor 2a
chr23_-_14057191 1.01 ENSDART00000154908
adenylate cyclase 6a
chr4_+_45274792 0.96 ENSDART00000150295
zinc finger protein 1138
chr19_-_40985308 0.95 ENSDART00000132986
ENSDART00000142360
si:ch211-120e1.7
chr17_-_1407593 0.92 ENSDART00000157622
ENSDART00000159458
zinc finger and BTB domain containing 42
chr4_+_64921810 0.92 ENSDART00000157654

chr8_-_45729248 0.90 ENSDART00000187736

chr17_-_8562586 0.89 ENSDART00000154257
ENSDART00000157308
frizzled class receptor 3b
chr5_-_14564878 0.88 ENSDART00000160511
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr4_+_6840223 0.88 ENSDART00000161329
dedicator of cytokinesis 4b
chr15_+_816556 0.87 ENSDART00000046783
zgc:113294
chr5_+_7393346 0.85 ENSDART00000164238
si:ch73-72b7.1
chr11_-_19097746 0.85 ENSDART00000103973
rhodopsin, like
chr8_-_53926228 0.79 ENSDART00000015554
UbiA prenyltransferase domain containing 1
chr5_+_13521081 0.78 ENSDART00000171975
si:ch211-230g14.6
chr19_+_15443353 0.77 ENSDART00000135923
lin-28 homolog A (C. elegans)
chr2_-_3616363 0.76 ENSDART00000144699
phosphotriesterase related
chr8_-_45729758 0.76 ENSDART00000189329

chr2_-_12242695 0.75 ENSDART00000158175
G protein-coupled receptor 158b
chr15_+_26941063 0.75 ENSDART00000149957
breast carcinoma amplified sequence 3
chr21_-_45073764 0.73 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr19_+_15443540 0.73 ENSDART00000193355
lin-28 homolog A (C. elegans)
chr5_+_36439405 0.73 ENSDART00000102973
ectodysplasin A
chr2_-_57707039 0.72 ENSDART00000097685

chr12_-_6905375 0.72 ENSDART00000152322
protocadherin-related 15b
chr23_+_31979602 0.70 ENSDART00000140351
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_-_40068350 0.69 ENSDART00000185292
myosin XVAa
chr19_+_5146460 0.67 ENSDART00000150740
si:dkey-89b17.4
chr18_+_3530769 0.67 ENSDART00000163469
si:ch73-338a16.3
chrM_+_8894 0.65 ENSDART00000093611
ATP synthase 8, mitochondrial
chr7_-_55292116 0.65 ENSDART00000122603
ring finger protein 166
chr22_-_20814450 0.63 ENSDART00000089076
DOT1-like histone H3K79 methyltransferase
chr14_-_48961056 0.62 ENSDART00000124192
si:dkeyp-121d2.7
chr5_+_20693724 0.61 ENSDART00000141368
si:ch211-240b21.2
chr13_+_36958086 0.60 ENSDART00000024386
FERM domain containing 6
chr4_+_38937575 0.59 ENSDART00000150385
zinc finger protein 997
chr23_+_12072980 0.58 ENSDART00000141646
endothelin 3b
chr15_+_31276869 0.58 ENSDART00000156355
si:ch211-244e12.7
chr14_+_24935131 0.58 ENSDART00000170871
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr6_+_46258866 0.58 ENSDART00000134584
zgc:162324
chr20_-_45060241 0.55 ENSDART00000185227
kelch-like family member 29
chr9_-_128036 0.54 ENSDART00000165960

chr5_+_38654215 0.53 ENSDART00000144473
si:dkey-58f10.14
chr19_-_46566430 0.52 ENSDART00000166668
exostosin glycosyltransferase 1b
chr4_-_72503156 0.51 ENSDART00000181914

chr2_+_51783120 0.49 ENSDART00000177559
crystallin, gamma N1
chr15_-_24178893 0.48 ENSDART00000077980
pipecolic acid oxidase
chr24_+_5799764 0.48 ENSDART00000154482
si:ch211-157j23.2
chr16_-_2558653 0.46 ENSDART00000110365
adenylate cyclase 3a
chr13_-_30713236 0.45 ENSDART00000112372
ENSDART00000142221
transmembrane protein 72
chr4_+_9679840 0.43 ENSDART00000190889

chr17_+_30587333 0.43 ENSDART00000156500
NHS-like 1a
chr19_+_43504480 0.43 ENSDART00000159421

chr16_+_54263921 0.42 ENSDART00000002856
dopamine receptor D2 like
chr22_+_11153590 0.41 ENSDART00000188207
BCL6 corepressor
chr24_+_24086249 0.40 ENSDART00000002953
lipase, member Ib
chr15_+_26940569 0.40 ENSDART00000189636
ENSDART00000077172
breast carcinoma amplified sequence 3
chr9_+_14023942 0.40 ENSDART00000142749
si:ch211-67e16.4
chr19_+_15443063 0.39 ENSDART00000151732
lin-28 homolog A (C. elegans)
chr5_+_36513605 0.37 ENSDART00000013590
wingless-type MMTV integration site family, member 11
chr12_-_124264 0.35 ENSDART00000181551

chr5_-_48070779 0.35 ENSDART00000078401
transmembrane protein 161B
chr22_+_2686673 0.34 ENSDART00000161580
si:dkey-20i20.15
chr19_+_2546775 0.33 ENSDART00000148527
ENSDART00000097528
sp4 transcription factor

Network of associatons between targets according to the STRING database.

First level regulatory network of zic2a+zic2b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.1 GO:0070208 protein heterotrimerization(GO:0070208)
1.0 2.9 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.9 3.5 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.7 6.8 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.7 5.3 GO:0090594 inflammatory response to wounding(GO:0090594)
0.7 13.1 GO:0014823 response to activity(GO:0014823)
0.6 2.5 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.6 2.3 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.5 4.2 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.5 2.6 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.5 1.4 GO:0048743 extraocular skeletal muscle development(GO:0002074) positive regulation of skeletal muscle fiber development(GO:0048743)
0.5 1.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.4 1.7 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.4 3.0 GO:0042311 vasodilation(GO:0042311)
0.3 3.8 GO:0098900 regulation of action potential(GO:0098900)
0.3 2.6 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.3 1.2 GO:0090299 regulation of neural crest formation(GO:0090299)
0.3 5.0 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.3 2.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.3 0.8 GO:0071498 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.2 10.7 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.2 1.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.2 3.2 GO:0001964 startle response(GO:0001964)
0.2 6.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 2.9 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 8.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 3.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 3.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.2 4.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 3.6 GO:0032438 melanosome organization(GO:0032438)
0.2 0.6 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.2 1.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.6 GO:0060585 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 18.5 GO:0051260 protein homooligomerization(GO:0051260)
0.1 3.5 GO:0021884 forebrain neuron development(GO:0021884)
0.1 1.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.5 GO:0019477 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 13.6 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.1 1.7 GO:0042407 cristae formation(GO:0042407)
0.1 2.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.5 GO:0030325 adrenal gland development(GO:0030325)
0.1 3.0 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 8.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 3.2 GO:0001885 endothelial cell development(GO:0001885)
0.1 1.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 1.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.3 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 1.1 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 1.9 GO:0048854 brain morphogenesis(GO:0048854)
0.0 2.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 3.8 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 1.0 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 1.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.5 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 1.1 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.7 GO:0042476 odontogenesis(GO:0042476)
0.0 1.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.4 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 3.8 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.1 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.0 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.0 0.6 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.2 GO:0002027 regulation of heart rate(GO:0002027)
0.0 4.3 GO:0008380 RNA splicing(GO:0008380)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0032839 dendrite cytoplasm(GO:0032839)
1.0 5.9 GO:0070062 extracellular exosome(GO:0070062)
0.8 3.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.7 6.8 GO:0098982 GABA-ergic synapse(GO:0098982)
0.6 7.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 5.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 1.3 GO:0044609 DBIRD complex(GO:0044609)
0.3 13.1 GO:0005861 troponin complex(GO:0005861)
0.3 2.3 GO:0016586 RSC complex(GO:0016586)
0.2 7.1 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.2 0.7 GO:0031251 PAN complex(GO:0031251)
0.2 14.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 3.2 GO:0031209 SCAR complex(GO:0031209)
0.2 3.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 1.7 GO:0061617 MICOS complex(GO:0061617)
0.2 12.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 3.9 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 1.7 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 3.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.4 GO:0005869 dynactin complex(GO:0005869)
0.1 4.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 17.8 GO:0030424 axon(GO:0030424)
0.1 2.1 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 2.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 2.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 2.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.8 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.4 GO:0005925 focal adhesion(GO:0005925)
0.0 2.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.7 GO:0030286 dynein complex(GO:0030286)
0.0 1.5 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 9.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.0 3.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.0 3.9 GO:0004949 cannabinoid receptor activity(GO:0004949)
1.0 2.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.6 5.2 GO:0015154 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.6 2.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.6 4.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.5 7.1 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.5 13.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.4 3.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.4 6.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.3 2.3 GO:0045735 nutrient reservoir activity(GO:0045735)
0.3 3.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 8.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 2.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.3 5.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 3.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.3 5.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 1.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 7.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 3.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 3.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 8.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 7.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 4.1 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.2 0.6 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.2 2.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 2.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 3.6 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.7 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 5.9 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 3.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.9 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.9 GO:0016918 retinal binding(GO:0016918)
0.1 1.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 1.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 1.4 GO:0002039 p53 binding(GO:0002039)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 2.9 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 1.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 8.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 6.8 GO:0042802 identical protein binding(GO:0042802)
0.0 2.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 11.2 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 5.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.1 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 5.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.8 GO:0000287 magnesium ion binding(GO:0000287)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 21.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 12.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.2 4.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 4.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 1.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 8.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.5 7.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 13.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 3.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 1.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 9.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 8.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 3.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 2.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 5.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 3.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 6.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis