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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for zic3

Z-value: 0.20

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Transcription factors associated with zic3

Gene Symbol Gene ID Gene Info
ENSDARG00000071497 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zic3dr11_v1_chr14_-_32016615_320166150.161.3e-01Click!

Activity profile of zic3 motif

Sorted Z-values of zic3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_27194833 3.37 ENSDART00000150072
si:dkey-85n7.8
chr19_+_23982466 1.07 ENSDART00000080673
synaptotagmin XIa
chr22_-_10487490 0.88 ENSDART00000064798
asporin (LRR class 1)
chr22_-_37565348 0.75 ENSDART00000149482
ENSDART00000104478
fragile X mental retardation, autosomal homolog 1
chr12_-_26582607 0.51 ENSDART00000045186
solute carrier family 16 (monocarboxylate transporter), member 5a
chr9_+_23770666 0.51 ENSDART00000182493
si:ch211-219a4.3
chr2_-_30784198 0.43 ENSDART00000182523
ENSDART00000147355
regulator of G protein signaling 20
chr6_+_27090800 0.39 ENSDART00000121558
autophagy related 4B, cysteine peptidase
chr25_-_34740627 0.39 ENSDART00000137665
fibroblast growth factor receptor substrate 2b
chr5_-_22615087 0.39 ENSDART00000146035
zgc:113208
chr21_-_30415524 0.36 ENSDART00000101036
GrpE-like 2, mitochondrial
chr11_+_34921492 0.26 ENSDART00000128070
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr4_-_56157199 0.23 ENSDART00000169806
si:ch211-207e19.15
chr8_+_49096486 0.18 ENSDART00000192998
zgc:56525
chr8_-_40075983 0.18 ENSDART00000141455
gamma-glutamyltransferase 1a
chr6_+_83873 0.15 ENSDART00000162145
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr12_+_27117609 0.06 ENSDART00000076154
homeobox B8b
chr19_+_9050852 0.06 ENSDART00000151031
ash1 (absent, small, or homeotic)-like (Drosophila)
chr21_-_45073764 0.04 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr23_-_14057191 0.03 ENSDART00000154908
adenylate cyclase 6a
chr20_-_40725142 0.03 ENSDART00000181279
connexin 32.2
chr2_+_2918759 0.02 ENSDART00000161255

chr22_-_6988102 0.00 ENSDART00000185618
fibroblast growth factor receptor 1b, like
chr21_-_21465111 0.00 ENSDART00000141487
nectin cell adhesion molecule 3b

Network of associatons between targets according to the STRING database.

First level regulatory network of zic3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.4 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 1.1 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.2 3.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.8 GO:0045182 translation regulator activity(GO:0045182)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans