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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for znf143b

Z-value: 0.93

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Transcription factors associated with znf143b

Gene Symbol Gene ID Gene Info
ENSDARG00000041581 zinc finger protein 143b
ENSDARG00000111018 zinc finger protein 143b
ENSDARG00000112408 zinc finger protein 143b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf143bdr11_v1_chr18_-_16937008_169371090.141.8e-01Click!

Activity profile of znf143b motif

Sorted Z-values of znf143b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_50310684 13.03 ENSDART00000112152
growth arrest-specific 7a
chr15_+_47161917 10.11 ENSDART00000167860
growth associated protein 43
chr23_+_35714574 9.96 ENSDART00000164616
tubulin, alpha 1c
chr25_-_13842618 8.32 ENSDART00000160258
mitogen-activated protein kinase 8 interacting protein 1a
chr6_-_27057702 7.02 ENSDART00000149363
serine/threonine kinase 25a
chr15_-_33933790 6.98 ENSDART00000165162
ENSDART00000182258
ENSDART00000183240
myelin associated glycoprotein
chr4_-_1324141 6.73 ENSDART00000180720
pleiotrophin
chr22_+_12366516 6.31 ENSDART00000157802
R3H domain containing 1
chr8_-_43158486 6.30 ENSDART00000134801
coiled-coil domain containing 92
chr21_-_16399778 6.25 ENSDART00000136435
unc-5 netrin receptor Da
chr15_-_9257136 6.08 ENSDART00000187901
calmodulin 2a (phosphorylase kinase, delta)
chr13_+_28819768 5.95 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653

chr5_+_54685175 5.88 ENSDART00000115016
pro-melanin-concentrating hormone, like
chr7_+_61050329 5.61 ENSDART00000115355
NACHT and WD repeat domain containing 2
chr6_-_48311 5.53 ENSDART00000131010
zgc:114175
chr4_+_25950372 5.31 ENSDART00000125767
methionyl aminopeptidase 2a
chr18_+_41495841 5.31 ENSDART00000098671
si:ch211-203b8.6
chr15_-_9419472 5.17 ENSDART00000122117
sacsin molecular chaperone
chr13_+_15816573 5.15 ENSDART00000137061
kinesin light chain 1a
chr5_+_20148671 4.98 ENSDART00000143205
SV2 related protein a
chr15_-_12500938 4.97 ENSDART00000159627
sodium channel, voltage-gated, type IV, beta a
chr19_-_7358184 4.84 ENSDART00000092379
oxidation resistance 1b
chr20_-_16849306 4.80 ENSDART00000131395
ENSDART00000027582
breast cancer metastasis-suppressor 1-like b
chr17_-_22067451 4.66 ENSDART00000156872
tau tubulin kinase 1b
chr24_+_15899365 4.55 ENSDART00000185965
neuropilin (NRP) and tolloid (TLL)-like 1, like
chr14_+_25465346 4.52 ENSDART00000173436
si:dkey-280e21.3
chr19_-_1023051 4.49 ENSDART00000158429
transmembrane protein 42b
chr5_-_71722257 4.45 ENSDART00000013404
adenylate kinase 1
chr9_-_27442339 4.40 ENSDART00000138602
syntaxin binding protein 5-like
chr23_-_24825863 4.29 ENSDART00000112493
synaptotagmin VIa
chr4_+_4232562 4.24 ENSDART00000177529
small lysine rich protein 1
chr10_-_27009413 4.06 ENSDART00000139942
ENSDART00000146983
ENSDART00000132352
ubiquinol-cytochrome c reductase complex assembly factor 3
chr24_+_39129316 4.02 ENSDART00000155346
TBC1 domain family, member 24
chr3_-_50127668 3.94 ENSDART00000062116
claudin k
chr5_+_65536095 3.90 ENSDART00000189898
si:dkey-21e5.1
chr5_-_68641353 3.82 ENSDART00000048432
discs, large homolog 4a (Drosophila)
chr5_+_42467867 3.79 ENSDART00000172028
Pim proto-oncogene, serine/threonine kinase, related 58
chr24_-_31843173 3.76 ENSDART00000185782
STEAP family member 2, metalloreductase
chr14_+_36521553 3.71 ENSDART00000136233
si:dkey-237h12.3
chr1_+_25848231 3.55 ENSDART00000027973
fatty acid binding protein 2, intestinal
chr15_-_47193564 3.45 ENSDART00000172453
limbic system-associated membrane protein
chr9_+_26086135 3.36 ENSDART00000011910
arginine and glutamate rich 1a
chr16_-_8132742 3.34 ENSDART00000104323
SNF related kinase a
chr10_-_7858553 3.25 ENSDART00000182010
inositol polyphosphate-5-phosphatase Ja
chr25_+_35706493 3.20 ENSDART00000176741
kinesin family member 21A
chr9_-_7257877 3.16 ENSDART00000153514
si:ch211-121j5.4
chr7_-_62003831 3.09 ENSDART00000113585
ENSDART00000062704
phospholipase A2-activating protein
chr17_+_25414033 3.08 ENSDART00000001691
L-threonine dehydrogenase 2
chr9_-_29985390 3.07 ENSDART00000134157
interleukin 1 receptor accessory protein-like 1a
chr6_+_53361874 3.05 ENSDART00000180660
si:ch211-161c3.5
chr2_+_6127593 2.95 ENSDART00000184007
fizzy/cell division cycle 20 related 1b
chr2_-_12243213 2.94 ENSDART00000113081
G protein-coupled receptor 158b
chr18_+_28102620 2.91 ENSDART00000132342
KIAA1549-like b
chr22_+_465269 2.91 ENSDART00000145767
cadherin, EGF LAG seven-pass G-type receptor 2
chr22_+_797105 2.82 ENSDART00000128549
cryptochrome circadian clock 1bb
chr21_+_21791343 2.70 ENSDART00000151654
sialidase 3 (membrane sialidase), tandem duplicate 1
chr25_-_20258508 2.68 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dynamin 1-like
chr2_+_11670270 2.59 ENSDART00000100524
finTRIM family, member 1
chr16_+_46000956 2.51 ENSDART00000101753
ENSDART00000162393
myotubularin related protein 11
chr20_-_35040041 2.50 ENSDART00000131919
kinesin family member 26Bb
chr11_-_41996957 2.50 ENSDART00000055706
hairy and enhancer of split-related 15, tandem duplicate 2
chr16_+_31511739 2.47 ENSDART00000049420
N-myc downstream regulated 1b
chr4_+_12111154 2.45 ENSDART00000036779
transmembrane protein 178B
chr19_+_41701660 2.40 ENSDART00000033362
GATA zinc finger domain containing 2B
chr6_-_53282572 2.40 ENSDART00000172615
ENSDART00000165036
RNA binding motif protein 5
chr3_-_30861177 2.38 ENSDART00000154811
SH3 and multiple ankyrin repeat domains 1
chr14_-_31562795 2.38 ENSDART00000034979
motile sperm domain containing 1
chr13_-_49819027 2.37 ENSDART00000067824
beta-1,3-N-acetylgalactosaminyltransferase 2
chr21_+_7605803 2.35 ENSDART00000121813
WD repeat domain 41
chr2_-_5942115 2.34 ENSDART00000154489
transmembrane protein 125b
chr13_+_33055548 2.34 ENSDART00000137315
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr15_-_766015 2.30 ENSDART00000190648
si:dkey-7i4.15
chr3_-_33573252 2.29 ENSDART00000191339
ENSDART00000184612
ENSDART00000187232
ENSDART00000190671

chr4_-_75047192 2.29 ENSDART00000193576
LARGE xylosyl- and glucuronyltransferase 1
chr7_-_11605185 2.29 ENSDART00000169291
ENSDART00000113904
StAR-related lipid transfer (START) domain containing 5
chr9_+_28693592 2.27 ENSDART00000110198
zgc:162780
chr10_+_42678520 2.16 ENSDART00000182496
Rho-related BTB domain containing 2b
chr17_-_14671098 2.15 ENSDART00000037371
protein phosphatase 1, regulatory subunit 13Ba
chr24_+_19591893 2.15 ENSDART00000152026
solute carrier organic anion transporter family member 5A1a
chr10_-_43392267 2.11 ENSDART00000142872
EGF-like repeats and discoidin I-like domains 3b
chr2_+_53357953 2.10 ENSDART00000187577
cugbp, Elav-like family member 5b
chr25_+_8662469 2.09 ENSDART00000154680
ENSDART00000188568
mannosidase, alpha, class 2A, member 2
chr7_+_427503 2.07 ENSDART00000185942
neurexin 2
chr24_-_13364311 2.01 ENSDART00000183808
si:dkey-192j17.1
chr5_-_62988463 1.99 ENSDART00000047143
sperm antigen with calponin homology and coiled-coil domains 1
chr21_+_21791799 1.97 ENSDART00000151759
sialidase 3 (membrane sialidase), tandem duplicate 1
chr22_+_696931 1.93 ENSDART00000149712
ENSDART00000009756
G protein-coupled receptor 37 like 1a
chr16_+_13822137 1.92 ENSDART00000163251
folliculin
chr24_+_19863246 1.91 ENSDART00000165242

chr14_+_25464681 1.91 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr15_-_11341635 1.89 ENSDART00000055220
RAB30, member RAS oncogene family
chr25_+_12012 1.88 ENSDART00000170348
contactin 1a
chr25_-_21609645 1.85 ENSDART00000087817
si:dkey-81e3.1
chr2_-_30912307 1.84 ENSDART00000188653
myosin, light chain 12, genome duplicate 2
chr20_-_37629084 1.84 ENSDART00000141734
human immunodeficiency virus type I enhancer binding protein 2a
chr19_+_19032141 1.80 ENSDART00000192432
copine IVb
chr19_+_177455 1.80 ENSDART00000111580
transmembrane protein 65
chr6_-_37468971 1.80 ENSDART00000126379
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr7_+_50766094 1.79 ENSDART00000165037
si:ch73-380l10.2
chr19_-_33996277 1.75 ENSDART00000159384
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr10_-_43392667 1.75 ENSDART00000183033
EGF-like repeats and discoidin I-like domains 3b
chr8_+_19977712 1.74 ENSDART00000134124
zinc finger protein 692
chr16_-_2558653 1.74 ENSDART00000110365
adenylate cyclase 3a
chr3_+_32477782 1.70 ENSDART00000151261
SR-related CTD-associated factor 1
chr23_-_4019928 1.68 ENSDART00000021062
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr12_-_46959990 1.65 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr15_+_21744680 1.64 ENSDART00000016860
protein phosphatase 2, regulatory subunit A, beta b
chr5_+_59534286 1.63 ENSDART00000189341
GTF2I repeat domain containing 1
chr14_+_41409697 1.54 ENSDART00000173335
BCL6 corepressor-like 1
chr3_+_18050667 1.53 ENSDART00000035531
methyltransferase like 26
chr19_+_1835940 1.53 ENSDART00000167372
protein tyrosine kinase 2aa
chr17_+_37253706 1.52 ENSDART00000076004
transmembrane protein 62
chr17_+_32571584 1.50 ENSDART00000087565
eva-1 homolog A (C. elegans)
chr14_-_21661015 1.50 ENSDART00000189403
ENSDART00000172442
ENSDART00000181913
lysine (K)-specific demethylase 3B
chr10_-_8434816 1.49 ENSDART00000108643
tectonic family member 1
chr13_+_30506781 1.49 ENSDART00000110884
zinc finger, MIZ-type containing 1a
chr17_-_14780578 1.48 ENSDART00000154690
si:ch211-266o15.1
chr14_-_30876708 1.45 ENSDART00000147597
ubiquitin-like 3b
chr8_-_44904723 1.45 ENSDART00000040804
PRA1 domain family, member 2
chr3_+_39568290 1.44 ENSDART00000020741
aldolase a, fructose-bisphosphate, a
chr14_+_32852388 1.43 ENSDART00000166351
NFKB repressing factor
chr1_-_55196103 1.40 ENSDART00000140153
methylthioribose-1-phosphate isomerase 1
chr24_+_39576071 1.39 ENSDART00000147137
si:dkey-161j23.6
chr10_+_31222656 1.35 ENSDART00000140988
ENSDART00000143387
transmembrane protein 218
chr3_-_40301467 1.34 ENSDART00000055186
ATP synthase membrane subunit f
chr12_-_48992527 1.32 ENSDART00000169696
cadherin related family member 1
chr5_-_23583446 1.30 ENSDART00000027217
CWC15 spliceosome-associated protein homolog (S. cerevisiae)
chr21_-_43482426 1.29 ENSDART00000192901
ankyrin repeat domain 46a
chr5_+_34549365 1.29 ENSDART00000009500
allograft inflammatory factor 1-like
chr3_+_62236443 1.29 ENSDART00000180482
ENSDART00000193718

chr17_-_2126517 1.28 ENSDART00000013093
zinc finger, FYVE domain containing 19
chr19_+_37458610 1.27 ENSDART00000103151
discs, large (Drosophila) homolog-associated protein 3
chr6_-_50730749 1.25 ENSDART00000157153
ENSDART00000110441
phosphatidylinositol glycan anchor biosynthesis, class U
chr22_-_2929127 1.24 ENSDART00000123730
ENSDART00000046678
p21 protein (Cdc42/Rac)-activated kinase 2b
chr11_-_2222440 1.22 ENSDART00000162167
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr3_+_62219158 1.22 ENSDART00000162354

chr22_-_18779232 1.21 ENSDART00000186726
ATP synthase F1 subunit delta
chr2_+_31437547 1.20 ENSDART00000141170
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr1_+_26099250 1.20 ENSDART00000054205
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6
chr7_+_67748939 1.17 ENSDART00000162978
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr18_+_36806545 1.16 ENSDART00000098958
tetratricopeptide repeat domain 9B
chr18_-_11060548 1.16 ENSDART00000146692
tetraspanin 9a
chr9_+_33158191 1.14 ENSDART00000180786
dopey family member 2
chr22_+_17531020 1.14 ENSDART00000137689
heterogeneous nuclear ribonucleoprotein M
chr15_+_5116179 1.14 ENSDART00000101937
phosphoglucomutase 2-like 1
chr15_+_44053244 1.12 ENSDART00000059550
leucine rich repeat containing 51
chr23_-_4019699 1.11 ENSDART00000159780
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr4_+_11483335 1.10 ENSDART00000184978
ENSDART00000140954
ankyrin repeat and SOCS box containing 13a, tandem duplicate 2
chr14_-_30876299 1.10 ENSDART00000180305
ubiquitin-like 3b
chr3_+_55031685 1.09 ENSDART00000132587
N-methylpurine DNA glycosylase
chr25_+_8925934 1.08 ENSDART00000073914
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr2_-_1227221 1.07 ENSDART00000130897
ATP binding cassette subfamily F member 3
chr22_-_506522 1.06 ENSDART00000106645
ENSDART00000067637
dual serine/threonine and tyrosine protein kinase
chr5_+_34549845 1.05 ENSDART00000139317
allograft inflammatory factor 1-like
chr15_-_1622468 1.04 ENSDART00000149008
ENSDART00000034456
karyopherin alpha 4 (importin alpha 3)
chr7_-_56180680 1.04 ENSDART00000098438
spastic paraplegia 7
chr23_+_31245395 1.03 ENSDART00000053588
interleukin-1 receptor-associated kinase 1 binding protein 1
chr7_+_62004048 1.01 ENSDART00000181818
small integral membrane protein 20
chr16_+_12267672 1.00 ENSDART00000060037
zgc:92606
chr25_+_23358924 0.97 ENSDART00000156965
oxysterol binding protein-like 5
chr11_+_5880562 0.96 ENSDART00000129663
ENSDART00000130768
ENSDART00000160909
DAZ associated protein 1
chr17_+_22760126 0.93 ENSDART00000151999
ENSDART00000190442
tetratricopeptide repeat domain 27
chr4_-_8058214 0.93 ENSDART00000132228
WNK lysine deficient protein kinase 1b
chr5_+_15495351 0.91 ENSDART00000111646
ENSDART00000114446
SDS3 homolog, SIN3A corepressor complex component
chr8_+_247163 0.90 ENSDART00000122378
centrosomal protein 120
chr1_+_55095314 0.90 ENSDART00000132727
aftiphilin a
chr2_+_42072689 0.89 ENSDART00000134203
valosin containing protein (p97)/p47 complex interacting protein 1
chr19_+_40069524 0.89 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr22_+_20172018 0.89 ENSDART00000188104
high mobility group 20B
chr1_+_44906517 0.87 ENSDART00000142820
wu:fc21g02
chr5_-_24642026 0.85 ENSDART00000139522
si:ch211-106a19.1
chr20_-_9428021 0.85 ENSDART00000025330
retinol dehydrogenase 14b
chr16_-_39900665 0.84 ENSDART00000136719
RNA binding motif, single stranded interacting protein
chr22_-_18778988 0.84 ENSDART00000019235
ATP synthase F1 subunit delta
chr19_+_15521997 0.84 ENSDART00000003164
protein phosphatase 1, regulatory subunit 8a
chr13_-_37127970 0.83 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr21_-_13493608 0.81 ENSDART00000192307
NMDA receptor synaptonuclear signaling and neuronal migration factor a
chr23_+_37185247 0.80 ENSDART00000146269
von Willebrand factor A domain containing 5B1
chr9_-_55946377 0.77 ENSDART00000161536
ENSDART00000169432
si:ch211-124n19.2
chr14_+_989733 0.77 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr5_+_13353866 0.77 ENSDART00000099611
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr19_-_12967986 0.77 ENSDART00000151064
solute carrier family 25 (mitochondrial folate carrier), member 32a
chr3_-_50066499 0.76 ENSDART00000056618
ENSDART00000154561
mitochondrial ribosomal protein L12
chr16_-_34212912 0.75 ENSDART00000145017
phosphatase and actin regulator 4b
chr17_+_5846202 0.74 ENSDART00000189713
fibronectin type III domain containing 4b
chr22_+_17531214 0.71 ENSDART00000161174
ENSDART00000088356
heterogeneous nuclear ribonucleoprotein M
chr21_+_7131970 0.71 ENSDART00000161921
zgc:113019
chr13_+_31133270 0.69 ENSDART00000014922
Rho GTPase activating protein 22
chr9_+_38624478 0.68 ENSDART00000077389
ENSDART00000114728
zinc finger protein 148
chr10_+_37182626 0.68 ENSDART00000137636
kinase suppressor of ras 1a
chr21_-_23046606 0.66 ENSDART00000016167
zw10 kinetochore protein
chr15_-_39848822 0.65 ENSDART00000155230
si:dkey-263j23.1
chr7_+_67749251 0.64 ENSDART00000167562
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr6_+_12482599 0.63 ENSDART00000090316
serine/threonine kinase 24b (STE20 homolog, yeast)
chr5_-_36949476 0.63 ENSDART00000047269
H3 histone, family 3C
chr15_-_47857687 0.62 ENSDART00000098982
ENSDART00000151594
H3 histone, family 3B.1
chr23_-_45318760 0.61 ENSDART00000166883
coiled-coil domain containing 171
chr1_+_53279861 0.61 ENSDART00000035713
ring finger protein 150a
chr10_+_26689262 0.61 ENSDART00000123195
ENSDART00000132946
teleost multiple tissue opsin 3b
chr17_+_31914877 0.60 ENSDART00000177801
family with sequence similarity 196 member A

Network of associatons between targets according to the STRING database.

First level regulatory network of znf143b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0070084 protein initiator methionine removal(GO:0070084)
1.2 3.5 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.9 3.8 GO:0015677 copper ion import(GO:0015677)
0.7 4.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.6 4.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.6 10.1 GO:0016198 axon choice point recognition(GO:0016198)
0.6 1.8 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.6 6.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.5 2.7 GO:1903146 regulation of mitophagy(GO:1903146)
0.5 2.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.5 1.4 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.5 1.9 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.4 3.5 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.4 1.3 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.4 2.1 GO:0006013 mannose metabolic process(GO:0006013)
0.4 4.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.4 3.1 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.3 1.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 1.9 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.3 2.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.2 1.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.9 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.2 2.9 GO:0021754 facial nucleus development(GO:0021754)
0.2 5.4 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.2 1.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 3.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.2 2.5 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.2 0.5 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 1.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 2.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 8.3 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 4.3 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.1 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 1.5 GO:0007172 signal complex assembly(GO:0007172)
0.1 2.3 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.5 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 6.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 7.0 GO:0003401 axis elongation(GO:0003401)
0.1 2.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.5 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 4.0 GO:0050708 regulation of protein secretion(GO:0050708)
0.1 1.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 2.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 5.7 GO:0016575 histone deacetylation(GO:0016575)
0.1 2.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 1.0 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 1.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 3.9 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 2.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.3 GO:0043111 replication fork arrest(GO:0043111)
0.1 1.4 GO:0001966 thigmotaxis(GO:0001966)
0.1 6.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 1.0 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 2.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 2.3 GO:0006284 base-excision repair(GO:0006284)
0.1 1.9 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.0 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.9 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 13.0 GO:0030041 actin filament polymerization(GO:0030041)
0.1 1.0 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 5.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 4.3 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.1 2.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 2.8 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 1.8 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 2.8 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 1.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.7 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.8 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.4 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.6 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 9.5 GO:0000278 mitotic cell cycle(GO:0000278)
0.0 0.5 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 3.3 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.5 GO:0006914 autophagy(GO:0006914)
0.0 0.6 GO:0007602 phototransduction(GO:0007602)
0.0 1.0 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.1 GO:0032584 growth cone membrane(GO:0032584)
0.5 2.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.4 4.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3 5.7 GO:0070822 Sin3-type complex(GO:0070822)
0.2 1.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 1.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 17.4 GO:0005884 actin filament(GO:0005884)
0.1 1.3 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 0.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 2.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.9 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 10.1 GO:0005871 kinesin complex(GO:0005871)
0.1 3.5 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.5 GO:0036038 MKS complex(GO:0036038)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 4.4 GO:0031201 SNARE complex(GO:0031201)
0.0 3.5 GO:0001726 ruffle(GO:0001726)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0036452 ESCRT complex(GO:0036452)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.5 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 8.3 GO:0005874 microtubule(GO:0005874)
0.0 4.3 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 3.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 3.8 GO:0010008 endosome membrane(GO:0010008)
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 6.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.1 GO:0005819 spindle(GO:0005819)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.0 GO:0099503 secretory vesicle(GO:0099503)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.5 GO:0005925 focal adhesion(GO:0005925)
0.0 0.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 4.3 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:1901612 cardiolipin binding(GO:1901612)
1.0 3.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.9 3.8 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.9 13.1 GO:0005504 fatty acid binding(GO:0005504)
0.6 6.2 GO:0005042 netrin receptor activity(GO:0005042)
0.6 3.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.6 2.9 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.4 3.5 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.4 4.7 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.4 1.7 GO:0101006 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.4 1.2 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.4 7.0 GO:0033691 sialic acid binding(GO:0033691)
0.4 2.3 GO:0032052 bile acid binding(GO:0032052)
0.3 5.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 4.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 3.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 4.4 GO:0045159 myosin II binding(GO:0045159)
0.3 0.8 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 2.8 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 1.0 GO:0034046 poly(G) binding(GO:0034046)
0.2 2.3 GO:0042285 xylosyltransferase activity(GO:0042285)
0.2 1.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 5.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 8.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 5.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 2.2 GO:0002039 p53 binding(GO:0002039)
0.1 1.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 5.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.5 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 1.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 1.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 4.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 2.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 3.9 GO:0005178 integrin binding(GO:0005178)
0.1 1.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.1 1.8 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.0 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.9 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 4.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 13.2 GO:0051015 actin filament binding(GO:0051015)
0.0 3.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.6 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 4.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 6.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 17.4 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.5 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.9 GO:0030276 clathrin binding(GO:0030276)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 3.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 9.3 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 10.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 2.3 PID CONE PATHWAY Visual signal transduction: Cones
0.1 7.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 6.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 4.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.7 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.1 1.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)