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PRJNA195909:zebrafish embryo and larva development

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Results for gsx1

Z-value: 1.24

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Transcription factors associated with gsx1

Gene Symbol Gene ID Gene Info
ENSDARG00000035735 GS homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gsx1dr11_v1_chr5_-_67911111_679111110.872.6e-03Click!

Activity profile of gsx1 motif

Sorted Z-values of gsx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31276842 4.30 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr7_+_20503344 3.03 ENSDART00000157699
si:dkey-19b23.12
chr15_+_23799461 3.01 ENSDART00000154885
si:ch211-167j9.4
chr21_+_28445052 2.71 ENSDART00000077871
phosphorylase, glycogen, muscle A
chr3_+_46635527 2.40 ENSDART00000153971
si:dkey-248g21.1
chr8_+_21353878 2.21 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr25_+_14507567 2.17 ENSDART00000015681
developing brain homeobox 1b
chr19_-_31402429 1.98 ENSDART00000137292
transmembrane protein 106Bb
chr9_-_21918963 1.97 ENSDART00000090782
LIM domain 7a
chr14_+_45406299 1.73 ENSDART00000173142
ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr15_-_21877726 1.64 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr16_+_5774977 1.63 ENSDART00000134202
cholecystokinin a
chr11_-_45138857 1.59 ENSDART00000166501
calcium activated nucleotidase 1b
chr15_+_46356879 1.59 ENSDART00000154388
wu:fb18f06
chr22_-_10121880 1.58 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr15_-_23376541 1.54 ENSDART00000078570
C1q and TNF related 5
chr24_-_6078222 1.53 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr9_-_32753535 1.44 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr19_+_43297546 1.42 ENSDART00000168002
lysosomal protein transmembrane 5
chr12_+_20352400 1.41 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr3_-_25814097 1.41 ENSDART00000169706
netrin 1b
chr20_+_19512727 1.35 ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr1_+_34696503 1.33 ENSDART00000186106

chr14_-_17072736 1.31 ENSDART00000106333
paired-like homeobox 2bb
chr11_+_10909183 1.31 ENSDART00000064860
RNA binding motif, single stranded interacting protein 1a
chr8_+_23738122 1.30 ENSDART00000062983
ribosomal protein L10a
chr21_-_23110841 1.26 ENSDART00000147896
ENSDART00000003076
ENSDART00000184925
ENSDART00000190386
ubiquitin specific peptidase 28
chr16_-_43344859 1.26 ENSDART00000058680
proteasome subunit alpha 2
chr25_-_5119162 1.24 ENSDART00000153961
shisa like 1b
chr20_+_52554352 1.23 ENSDART00000153217
ENSDART00000145230
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr18_+_24921587 1.21 ENSDART00000191345
repulsive guidance molecule family member a
chr24_+_9412450 1.21 ENSDART00000132724
si:ch211-285f17.1
chr15_-_1822548 1.19 ENSDART00000082026
ENSDART00000180230
matrix metallopeptidase 28
chr13_+_27232848 1.18 ENSDART00000138043
Ras and Rab interactor 2
chr21_-_37973819 1.17 ENSDART00000133405
ripply transcriptional repressor 1
chr15_-_22074315 1.16 ENSDART00000149830
dopamine receptor D2a
chr25_+_5068442 1.15 ENSDART00000097522
parvin, gamma
chr12_+_3078221 1.15 ENSDART00000148835
ENSDART00000149427
sarcoglycan, alpha
chr9_+_25776971 1.14 ENSDART00000146011
zinc finger E-box binding homeobox 2a
chr9_-_6372535 1.13 ENSDART00000149189
esophageal cancer related gene 4a
chr14_-_4273396 1.12 ENSDART00000127318
FERM and PDZ domain containing 1b
chr19_-_42571829 1.11 ENSDART00000102606
zgc:103438
chr16_+_31804590 1.08 ENSDART00000167321
wingless-type MMTV integration site family, member 4b
chr15_+_1796313 1.08 ENSDART00000126253
family with sequence similarity 124B
chr2_+_16160906 1.07 ENSDART00000135783
selenoprotein J
chr10_+_16584382 1.06 ENSDART00000112039

chr5_+_27897504 1.05 ENSDART00000130936
ADAM metallopeptidase domain 28
chr16_-_28878080 1.02 ENSDART00000149501
si:dkey-239n17.4
chr8_-_25336589 1.01 ENSDART00000009682
ATP synthase peripheral stalk-membrane subunit b
chr21_-_22827548 0.99 ENSDART00000079161
angiopoietin-like 5
chr1_+_55293424 0.98 ENSDART00000152464
zgc:172106
chr19_+_14921000 0.97 ENSDART00000144052
opioid receptor, delta 1a
chr10_+_31646020 0.97 ENSDART00000115251
endothelial cell adhesion molecule a
chr4_-_9891874 0.95 ENSDART00000067193
adrenomedullin 2a
chr19_-_42556086 0.93 ENSDART00000051731
si:dkey-267n13.1
chr3_+_46459540 0.89 ENSDART00000188150
si:ch211-66e2.5
chr9_+_21146862 0.88 ENSDART00000136365
hydroxyacid oxidase 2 (long chain)
chr5_-_33287691 0.87 ENSDART00000004238
ribosomal protein L7a
chr8_-_18537866 0.86 ENSDART00000148802
ENSDART00000148962
ENSDART00000149506
nexilin (F actin binding protein)
chr2_-_11512819 0.83 ENSDART00000142013
proenkephalin a
chr17_+_53425037 0.82 ENSDART00000154983
fatty acid binding protein 10b, liver basic
chr24_-_40744672 0.82 ENSDART00000160672

chr6_-_46941245 0.80 ENSDART00000037875
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 1
chr19_+_10339538 0.80 ENSDART00000151808
ENSDART00000151235
recoverin 3
chr20_+_10723292 0.79 ENSDART00000152805
si:ch211-182e10.4
chr15_+_36309070 0.79 ENSDART00000157034
geminin coiled-coil domain containing
chr23_+_40460333 0.78 ENSDART00000184658
SOGA family member 3b
chr13_+_29238850 0.74 ENSDART00000026000
myoferlin like
chr25_+_32755485 0.73 ENSDART00000162188
electron-transfer-flavoprotein, alpha polypeptide
chr8_+_24747865 0.73 ENSDART00000078656
solute carrier family 16, member 4
chr13_+_28903959 0.73 ENSDART00000166435
si:ch73-28h20.1
chr23_+_11285662 0.72 ENSDART00000111028
cell adhesion molecule L1-like a
chr6_+_39232245 0.72 ENSDART00000187351
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr1_-_50859053 0.71 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr8_+_30452945 0.71 ENSDART00000062303
forkhead box D5
chr24_-_37640705 0.70 ENSDART00000066583
zgc:112496
chr25_-_6011034 0.70 ENSDART00000075197
ENSDART00000136054
sorting nexin 22
chr9_-_20372977 0.70 ENSDART00000113418
immunoglobulin superfamily, member 3
chr8_-_17167819 0.69 ENSDART00000135042
ENSDART00000143920
mitochondrial ribosomal protein S36
chr7_+_69653981 0.68 ENSDART00000090165
Fras1 related extracellular matrix 1a
chr6_+_53349966 0.68 ENSDART00000167079
si:ch211-161c3.5
chr6_-_32999646 0.67 ENSDART00000159510
adenylate cyclase activating polypeptide 1b (pituitary) receptor type I
chr24_+_6107901 0.66 ENSDART00000156419
si:ch211-37e10.2
chr4_+_5798223 0.65 ENSDART00000059440
si:ch73-352p4.8
chr4_+_11479705 0.65 ENSDART00000019458
ENSDART00000150587
ENSDART00000139370
ENSDART00000135826
ankyrin repeat and SOCS box containing 13a, tandem duplicate 1
chr10_+_21867307 0.64 ENSDART00000126629
cerebellin 17
chr17_-_23416897 0.63 ENSDART00000163391
si:ch211-149k12.3
chr7_+_756942 0.62 ENSDART00000152224
zgc:63470
chr9_-_31278048 0.62 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr21_-_17296789 0.62 ENSDART00000192180
growth factor independent 1B transcription repressor
chr9_-_52962521 0.61 ENSDART00000170419

chr8_+_46641314 0.60 ENSDART00000113803
hairy-related 3
chr8_+_23521974 0.57 ENSDART00000188130
ENSDART00000129378
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr11_-_29737088 0.57 ENSDART00000159828
si:ch211-218g23.6
chr13_-_20381485 0.57 ENSDART00000131351
si:ch211-270n8.1
chr8_-_25120231 0.57 ENSDART00000147308
adhesion molecule with Ig-like domain 1
chr3_+_32553714 0.56 ENSDART00000165638
paired box 10
chr18_+_14564085 0.55 ENSDART00000009363
ENSDART00000141813
ENSDART00000136120
si:dkey-246g23.4
chr5_+_37840914 0.55 ENSDART00000097738
pannexin 1b
chr2_-_23768818 0.54 ENSDART00000148685
ENSDART00000191167
xin actin binding repeat containing 1
chr5_-_21970881 0.54 ENSDART00000182907
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr4_+_52356485 0.53 ENSDART00000170639
zgc:173705
chr1_-_10647307 0.53 ENSDART00000103548
si:dkey-31e10.1
chr14_+_30795559 0.52 ENSDART00000006132
cofilin 1
chr20_-_46362606 0.52 ENSDART00000153087
BCL2 modifying factor 2
chr24_+_17007407 0.52 ENSDART00000110652
zinc finger protein, X-linked
chr6_-_46861676 0.52 ENSDART00000188712
ENSDART00000190148
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr22_-_11137268 0.52 ENSDART00000178882
ATPase H+ transporting accessory protein 2
chr21_-_40174647 0.52 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
solute carrier organic anion transporter family, member 2B1
chr8_-_23612462 0.50 ENSDART00000025024
solute carrier family 38, member 5b
chr22_+_20427170 0.50 ENSDART00000136744
forkhead box Q2
chr14_-_21959712 0.50 ENSDART00000021417
purinergic receptor P2X, ligand-gated ion channel, 3a
chr2_-_10600950 0.49 ENSDART00000160216

chr11_+_30057762 0.49 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr11_+_36665359 0.48 ENSDART00000166144
si:ch211-11c3.9
chr12_+_10631266 0.48 ENSDART00000161455
colony stimulating factor 3 (granulocyte) a
chr1_-_10647484 0.48 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
chr2_-_59285085 0.48 ENSDART00000131880
finTRIM family, member 34
chr18_-_6982499 0.47 ENSDART00000101525
si:dkey-266m15.6
chr1_+_33668236 0.46 ENSDART00000122316
ENSDART00000102184
ADP-ribosylation factor-like 13b
chr7_+_2236317 0.46 ENSDART00000075859
zgc:172065
chr3_-_29941357 0.45 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
granulin a
chr3_-_32169754 0.45 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr1_+_55239160 0.45 ENSDART00000152318
si:ch211-286b5.2
chr13_+_35637048 0.45 ENSDART00000085037
thrombospondin 2a
chr19_-_30524952 0.45 ENSDART00000103506
hippocalcin like 4
chr22_-_12746539 0.44 ENSDART00000175374
phospholipase C, delta 4a
chr15_+_9053059 0.44 ENSDART00000012039
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr17_+_46818521 0.42 ENSDART00000156022
Pim proto-oncogene, serine/threonine kinase, related 14
chr1_-_9123465 0.40 ENSDART00000081337
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1a
chr15_-_19705707 0.39 ENSDART00000047643
synaptotagmin-like 2b
chr25_+_20715950 0.39 ENSDART00000180223
ERGIC and golgi 2
chr5_-_44286987 0.38 ENSDART00000184112
si:ch73-337l15.2
chr25_-_26758253 0.38 ENSDART00000123004
si:dkeyp-73b11.8
chr8_+_8936912 0.37 ENSDART00000135958
si:dkey-83k24.5
chr11_-_42980535 0.37 ENSDART00000181160
ENSDART00000192064

chr4_-_51460013 0.36 ENSDART00000193382

chr19_+_2279051 0.35 ENSDART00000182103
integrin, beta 8
chr23_+_31913292 0.34 ENSDART00000136910
armadillo repeat containing 1, like
chr20_-_52902693 0.34 ENSDART00000166115
ENSDART00000161050
cathepsin Bb
chr14_+_7377552 0.33 ENSDART00000142158
ENSDART00000141471
histidyl-tRNA synthetase
chr15_-_25518084 0.33 ENSDART00000158594
hypoxia-inducible factor 1, alpha subunit, like
chr8_-_50888806 0.33 ENSDART00000053750
acyl-CoA synthetase long chain family member 2
chr16_-_24605969 0.33 ENSDART00000163305
ENSDART00000167121
FXYD domain containing ion transport regulator 6 like
chr19_-_12315693 0.33 ENSDART00000151158
neurocalcin delta b
chr22_-_8725768 0.32 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
chr4_-_71210030 0.32 ENSDART00000186473
si:ch211-205a14.7
chr2_+_3986083 0.31 ENSDART00000188979
mohawk homeobox b
chr14_+_33329761 0.31 ENSDART00000161138
sosondowah ankyrin repeat domain family d
chr14_+_22022441 0.31 ENSDART00000149121
cardiotrophin-like cytokine factor 1
chr4_-_42408339 0.30 ENSDART00000172612
si:ch211-59d8.3
chr19_+_46237665 0.29 ENSDART00000159391
vacuolar protein sorting 28 (yeast)
chr1_+_31110817 0.29 ENSDART00000137863
eukaryotic translation elongation factor 1 alpha 1b
chr15_+_34988148 0.29 ENSDART00000076269
coiled-coil domain containing 105
chr2_+_33326522 0.28 ENSDART00000056655
Kruppel-like factor 17
chr25_+_16689633 0.28 ENSDART00000073416
adenosine deaminase 2a
chr8_+_48484455 0.28 ENSDART00000122737
si:ch211-263k4.2
chr15_-_31323932 0.27 ENSDART00000132455
odorant receptor, family F, subfamily 118, member 2
chr17_-_45386546 0.27 ENSDART00000182647
transmembrane protein 206
chr21_-_45077429 0.26 ENSDART00000187268
ENSDART00000191003
Rap guanine nucleotide exchange factor (GEF) 6
chr2_+_19578446 0.26 ENSDART00000164758
Pim proto-oncogene, serine/threonine kinase, related 50
chr20_-_47188966 0.26 ENSDART00000152965
si:dkeyp-104f11.9
chr4_+_9400012 0.26 ENSDART00000191960
transmembrane and tetratricopeptide repeat containing 1
chr10_+_2799285 0.25 ENSDART00000030709
posterior neuron-specific homeobox
chr11_+_14284866 0.25 ENSDART00000163729
si:ch211-262i1.3
chr20_+_42978499 0.24 ENSDART00000138793
si:ch211-203k16.3
chr13_+_15190677 0.23 ENSDART00000142240
ENSDART00000129045
mitochondrial antiviral signaling protein
chr20_-_35040041 0.22 ENSDART00000131919
kinesin family member 26Bb
chr2_-_51511494 0.22 ENSDART00000161392
ENSDART00000160877
si:ch211-9d9.8
chr9_+_23224761 0.22 ENSDART00000142008
mitogen-activated protein kinase kinase kinase 19
chr22_-_36530902 0.20 ENSDART00000056188
info polymerase (RNA) II (DNA directed) polypeptide H
chr13_+_29462249 0.20 ENSDART00000147903
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1a
chr9_+_41156818 0.20 ENSDART00000105764
ENSDART00000147052
signal transducer and activator of transcription 4
chr3_+_1637358 0.19 ENSDART00000180266

chr18_+_7073130 0.19 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
chr22_+_10660140 0.19 ENSDART00000105835
ENSDART00000038511
tumor suppressor candidate 2b
chr11_+_24703108 0.19 ENSDART00000159173
G protein-coupled receptor 25
chr4_+_9177997 0.18 ENSDART00000057254
ENSDART00000154614
nuclear transcription factor Y, beta a
chr25_-_27722614 0.18 ENSDART00000190154
zgc:153935
chr8_-_13184989 0.17 ENSDART00000135738
zgc:194990
chr20_+_39457598 0.17 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr10_+_40633990 0.16 ENSDART00000190489
ENSDART00000139474
si:ch211-238p8.31
chr8_+_23355484 0.16 ENSDART00000085361
ENSDART00000125729
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr21_-_7035599 0.16 ENSDART00000139777
si:ch211-93g21.1
chr22_-_10586191 0.16 ENSDART00000148418
si:dkey-42i9.16
chr23_+_404975 0.15 ENSDART00000181336

chr10_+_40756352 0.15 ENSDART00000156210
ENSDART00000144576
trace amine associated receptor 19f
chr25_+_28825657 0.14 ENSDART00000153625
nuclear transcription factor Y, beta b
chr6_+_41191482 0.13 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chrM_+_9735 0.13 ENSDART00000093613
cytochrome c oxidase III, mitochondrial
chr11_+_36231248 0.12 ENSDART00000131104
si:ch211-213o11.11
chr7_+_38509333 0.12 ENSDART00000153482
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr8_+_25034544 0.12 ENSDART00000123300
neugrin, neurite outgrowth associated
chr12_+_16168342 0.12 ENSDART00000079326
ENSDART00000170024
low density lipoprotein receptor-related protein 2b
chr6_-_40581376 0.11 ENSDART00000185412
translocator protein
chr15_-_41457898 0.11 ENSDART00000188847
NLR family CARD domain containing 9
chr21_+_43404945 0.10 ENSDART00000142234
FERM domain containing 7
chr3_-_17716322 0.09 ENSDART00000192664

chr4_+_43246676 0.09 ENSDART00000187588
si:dkey-29j8.1
chr21_+_35041399 0.09 ENSDART00000188183
ENSDART00000021645
KDEL (Lys-Asp-Glu-Leu) containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of gsx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.5 1.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.4 1.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.4 1.4 GO:0021742 abducens nucleus development(GO:0021742)
0.3 1.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.3 1.6 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.3 1.3 GO:0061549 sympathetic ganglion development(GO:0061549)
0.3 1.6 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.2 1.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 1.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 1.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 0.8 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 0.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.2 3.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.4 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.5 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.9 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 2.0 GO:0032418 lysosome localization(GO:0032418)
0.1 0.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 4.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 1.7 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 1.0 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.5 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.8 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 1.4 GO:0015671 oxygen transport(GO:0015671)
0.1 0.5 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.3 GO:0046102 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.0 1.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 1.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 1.6 GO:0007586 digestion(GO:0007586)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0048841 regulation of axon extension involved in axon guidance(GO:0048841)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 1.1 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 2.2 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.6 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.4 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 1.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.3 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.3 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.7 GO:0021854 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 1.2 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.7 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.0 0.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.0 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.6 GO:0042627 chylomicron(GO:0042627)
0.1 1.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 4.8 GO:0005861 troponin complex(GO:0005861)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.2 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.8 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.5 2.7 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.3 1.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 1.0 GO:0038046 enkephalin receptor activity(GO:0038046)
0.1 0.4 GO:0000035 acyl binding(GO:0000035)
0.1 1.4 GO:0031720 haptoglobin binding(GO:0031720)
0.1 1.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.8 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.9 GO:0010181 FMN binding(GO:0010181)
0.0 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.8 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0022829 wide pore channel activity(GO:0022829)
0.0 1.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0051020 GTPase binding(GO:0051020)
0.0 0.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.0 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 2.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport