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PRJNA195909:zebrafish embryo and larva development

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Results for hmx4

Z-value: 0.81

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Transcription factors associated with hmx4

Gene Symbol Gene ID Gene Info
ENSDARG00000007941 H6 family homeobox 4
ENSDARG00000115000 H6 family homeobox 4
ENSDARG00000116208 H6 family homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hmx4dr11_v1_chr1_-_40911332_409113320.127.6e-01Click!

Activity profile of hmx4 motif

Sorted Z-values of hmx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_992458 0.95 ENSDART00000114655
beaded filament structural protein 1
chr12_+_21299338 0.61 ENSDART00000074540
ENSDART00000133188
carbonic anhydrase Xa
chr20_+_36820965 0.61 ENSDART00000153085
ENSDART00000062935
hdc homolog, cell cycle regulator
chr17_-_38887424 0.60 ENSDART00000141177
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr3_-_5067585 0.52 ENSDART00000169609
thyrotrophic embryonic factor b
chr13_-_361196 0.51 ENSDART00000093160
ch1073-291c23.1
chr21_+_34167178 0.49 ENSDART00000158308
transient receptor potential cation channel, subfamily C, member 5b
chr12_-_17810543 0.46 ENSDART00000090484
tectonin beta-propeller repeat containing 1a
chr16_+_26547152 0.45 ENSDART00000141393
protein tyrosine phosphatase, non-receptor type 3
chr23_+_45822935 0.45 ENSDART00000161892
vitamin D receptor a
chr7_-_51749683 0.44 ENSDART00000083190
histone deacetylase 8
chr14_-_14659023 0.43 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr2_-_49978227 0.42 ENSDART00000142835
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1b
chr16_+_12022543 0.42 ENSDART00000012673
guanine nucleotide binding protein (G protein), beta polypeptide 3a
chr2_-_1279387 0.38 ENSDART00000192210

chr12_-_10512911 0.38 ENSDART00000124562
ENSDART00000106163
zgc:152977
chr11_+_45233348 0.38 ENSDART00000173150
transmembrane channel-like 6b
chr3_+_54012708 0.38 ENSDART00000154542
olfactomedin 2a
chr3_+_37824268 0.38 ENSDART00000137038
acid-sensing (proton-gated) ion channel 2
chr3_+_52545400 0.36 ENSDART00000184183
solute carrier family 27 (fatty acid transporter), member 1a
chr18_+_27077853 0.36 ENSDART00000125326
ENSDART00000192660
ENSDART00000098334
protein phosphatase 1, regulatory subunit 15B
chr12_+_4222854 0.35 ENSDART00000144881
mitogen-activated protein kinase 7
chr8_-_4031121 0.34 ENSDART00000169474
ENSDART00000163754
myotubularin related protein 3
chr5_+_16117871 0.34 ENSDART00000090657
zinc and ring finger 3
chr23_+_44307996 0.34 ENSDART00000042430
discs, large homolog 4b (Drosophila)
chr20_+_23625387 0.34 ENSDART00000147945
ENSDART00000150497
palladin, cytoskeletal associated protein
chr23_+_19564392 0.34 ENSDART00000144746
ATPase H+ transporting accessory protein 1 like b
chr6_+_32382743 0.34 ENSDART00000190009
dedicator of cytokinesis 7
chr9_-_44642108 0.33 ENSDART00000086202
phosphodiesterase 1A, calmodulin-dependent
chr13_+_38814521 0.33 ENSDART00000110976
collagen, type XIX, alpha 1
chr12_-_33357655 0.32 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr2_+_26060528 0.32 ENSDART00000058111
glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba
chr9_+_4252839 0.32 ENSDART00000169740
kalirin RhoGEF kinase a
chr25_+_17689565 0.32 ENSDART00000171965
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr17_-_25395395 0.31 ENSDART00000170233
family with sequence similarity 167, member B
chr8_-_21184759 0.30 ENSDART00000139257
glutaminase 2a (liver, mitochondrial)
chr2_-_48375342 0.30 ENSDART00000148788
period circadian clock 2
chr14_+_35424539 0.29 ENSDART00000171809
ENSDART00000162185
synaptotagmin-like 4
chr10_+_14982977 0.29 ENSDART00000140869
si:dkey-88l16.3
chr19_+_8612839 0.29 ENSDART00000144925
sorting nexin family member 27a
chr10_+_14963898 0.29 ENSDART00000187363
ENSDART00000175732
si:dkey-88l16.3
chr13_-_7031033 0.29 ENSDART00000193211

chr1_+_45839927 0.28 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
mitogen-activated protein kinase kinase 7
chr19_-_13774502 0.28 ENSDART00000159711
erythrocyte membrane protein band 4.1a
chr4_-_17263210 0.28 ENSDART00000147853
lymphoid-restricted membrane protein
chr1_-_14234076 0.28 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr3_+_37827373 0.27 ENSDART00000039517
acid-sensing (proton-gated) ion channel 2
chr1_+_10378706 0.27 ENSDART00000046283
ENSDART00000103535
ENSDART00000132076
dachshund b
chr21_-_23475361 0.27 ENSDART00000156658
ENSDART00000157454
neural cell adhesion molecule 1a
chr16_-_32975951 0.27 ENSDART00000101969
ENSDART00000175149
malic enzyme 1, NADP(+)-dependent, cytosolic
chr3_-_34586403 0.26 ENSDART00000151515
septin 9a
chr2_-_32574944 0.26 ENSDART00000056642
transmembrane and ubiquitin-like domain containing 1
chr12_-_4301234 0.26 ENSDART00000152377
ENSDART00000152521
carbonic anhydrase XVb
chr3_+_32553714 0.26 ENSDART00000165638
paired box 10
chr15_-_33325019 0.26 ENSDART00000181092
ENSDART00000168920
neurobeachin b
chr7_-_10606 0.26 ENSDART00000192650
ENSDART00000186761

chr2_+_53359234 0.25 ENSDART00000147581
cugbp, Elav-like family member 5b
chr13_-_30700460 0.25 ENSDART00000139073
Ras association (RalGDS/AF-6) domain family member 4
chr18_-_46763170 0.25 ENSDART00000171880
delta/notch-like EGF repeat containing
chr23_-_30076950 0.24 ENSDART00000180139
calmodulin binding transcription activator 1a
chr15_+_19544052 0.24 ENSDART00000062560
zgc:77784
chr15_+_45640906 0.24 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr3_-_54992934 0.24 ENSDART00000053095
ENSDART00000145766
rhomboid 5 homolog 1a (Drosophila)
chr6_+_4299164 0.23 ENSDART00000159759
neurobeachin-like 1
chr19_+_20495249 0.23 ENSDART00000090810
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr4_-_4507761 0.23 ENSDART00000130588
TBC1 domain family, member 30
chr18_+_184746 0.23 ENSDART00000140897
La ribonucleoprotein domain family, member 6a
chr3_+_41731527 0.23 ENSDART00000049007
ENSDART00000187866
carbohydrate (chondroitin 4) sulfotransferase 12a
chr3_-_28750495 0.23 ENSDART00000054408
gsg1-like
chr3_-_60571218 0.23 ENSDART00000178981
si:ch73-366l1.5
chr1_-_14233815 0.22 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr9_+_34434943 0.22 ENSDART00000175455
si:ch211-269e2.1
chr13_+_33655404 0.22 ENSDART00000023379
mitochondrial genome maintenance exonuclease 1
chr9_+_38888025 0.22 ENSDART00000148306
microtubule-associated protein 2
chr17_-_31483469 0.21 ENSDART00000062907
ENSDART00000061547
leukocyte receptor tyrosine kinase
chr8_-_19467011 0.21 ENSDART00000162010
zgc:92140
chr23_+_45906137 0.21 ENSDART00000159939
ATP-binding cassette, sub-family G (WHITE), member 2a
chr3_-_41292275 0.21 ENSDART00000144088
sidekick cell adhesion molecule 1a
chr3_+_32862730 0.21 ENSDART00000144939
ENSDART00000125126
ENSDART00000144531
ENSDART00000141717
ENSDART00000137599
zgc:162613
chr12_+_46543572 0.21 ENSDART00000167510
HID1 domain containing b
chr24_-_20320480 0.21 ENSDART00000137366
mitogen-activated protein kinase kinase kinase 20
chr7_+_30725759 0.21 ENSDART00000127131
myotubularin related protein 10
chr15_-_36533322 0.21 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
chr9_+_54290896 0.21 ENSDART00000149175
POU class 4 homeobox 3
chr1_-_45889820 0.21 ENSDART00000144735
patatin-like phospholipase domain containing 6
chr15_+_22867174 0.21 ENSDART00000035812
glutamate receptor, ionotropic, kainate 4
chr16_-_27138478 0.21 ENSDART00000147438
transmembrane protein 245
chr9_-_47472998 0.21 ENSDART00000134480
tensin 1b
chr6_+_60112200 0.21 ENSDART00000008243
PRELI domain containing 3
chr10_+_31809226 0.20 ENSDART00000087898
forkhead box O1 b
chr24_+_12835935 0.20 ENSDART00000114762
nanog homeobox
chr3_-_18373425 0.20 ENSDART00000178522
sperm associated antigen 9a
chr20_-_16078741 0.20 ENSDART00000021550
Ral GEF with PH domain and SH3 binding motif 2
chr19_+_2602903 0.20 ENSDART00000033132
family with sequence similarity 126, member A
chr15_-_47193564 0.20 ENSDART00000172453
limbic system-associated membrane protein
chr13_-_24874950 0.20 ENSDART00000077775
K(lysine) acetyltransferase 6B
chr3_-_55525627 0.20 ENSDART00000189234
testis expressed 2
chr7_+_22543963 0.19 ENSDART00000101528
cholinergic receptor, nicotinic, beta 1 (muscle)
chr1_+_8662530 0.19 ENSDART00000054989
fascin actin-bundling protein 1b
chr15_-_27710513 0.19 ENSDART00000005641
ENSDART00000134373
LIM homeobox 1a
chr22_+_29113796 0.19 ENSDART00000150264
phospholipase A2, group VI (cytosolic, calcium-independent)
chr6_-_25181012 0.19 ENSDART00000161585
leucine rich repeat containing 8 VRAC subunit Db
chr20_-_32112818 0.19 ENSDART00000142653
glutamate receptor, metabotropic 1a
chr18_+_39067575 0.19 ENSDART00000077724
guanine nucleotide binding protein (G protein), beta 5b
chr14_+_8275115 0.19 ENSDART00000129055
neuregulin 2b
chr3_-_28209001 0.19 ENSDART00000151178
RNA binding fox-1 homolog 1
chr14_+_1719367 0.19 ENSDART00000157696
transient receptor potential cation channel, subfamily C, member 7b
chr16_+_22345513 0.18 ENSDART00000078000
zgc:123238
chr12_+_36428052 0.18 ENSDART00000131300
unkempt family zinc finger
chr2_-_50225411 0.18 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr24_+_42148140 0.18 ENSDART00000010658
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr24_-_42148339 0.18 ENSDART00000112680
regulator of microtubule dynamics 1
chr25_+_17925424 0.18 ENSDART00000067305
zgc:103499
chr19_+_5674907 0.18 ENSDART00000042189
pyruvate dehydrogenase kinase, isozyme 2b
chr19_+_43669122 0.18 ENSDART00000139151
si:ch211-193k19.1
chr16_+_28881235 0.18 ENSDART00000146525
chromatin target of PRMT1b
chr12_+_1286642 0.18 ENSDART00000157467
phosphatidylethanolamine N-methyltransferase
chr18_-_41163764 0.18 ENSDART00000192951

chr21_+_17768174 0.18 ENSDART00000141380
retinoid X receptor, alpha a
chr21_-_37790727 0.17 ENSDART00000162907
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr18_+_50275933 0.17 ENSDART00000143911
si:dkey-105e17.1
chr5_-_23117078 0.17 ENSDART00000051529
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr14_-_31060082 0.17 ENSDART00000111601
ENSDART00000161113
muscleblind-like splicing regulator 3
chr24_+_17256793 0.17 ENSDART00000066764
COMM domain containing 3
chr6_+_39836474 0.17 ENSDART00000112637
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr6_-_20707846 0.16 ENSDART00000169836
collagen type XVIII alpha 1 chain b
chr2_-_11662851 0.16 ENSDART00000145108
zgc:110130
chr9_+_8761099 0.16 ENSDART00000159077
collagen, type IV, alpha 2
chr12_-_26538823 0.16 ENSDART00000143213
acyl-CoA synthetase family member 2
chr17_+_584369 0.16 ENSDART00000165143
chromosome 14 open reading frame 28
chr14_+_21699414 0.16 ENSDART00000169942
syntaxin 3A
chr23_+_2560005 0.16 ENSDART00000186906
gamma-glutamyltransferase 7
chr1_+_23274710 0.16 ENSDART00000036448
lipoic acid synthetase
chr25_+_35774544 0.16 ENSDART00000034737
ENSDART00000188162
copine VIII
chr25_-_225964 0.16 ENSDART00000193424

chr23_-_26532696 0.15 ENSDART00000124811
ENSDART00000180274
si:dkey-205h13.2
chr1_+_157793 0.15 ENSDART00000152205
cullin 4A
chr3_+_40409100 0.15 ENSDART00000103486
trinucleotide repeat containing 18
chr23_-_35347714 0.15 ENSDART00000161770
ENSDART00000165615
copine family member IX
chr6_-_12135741 0.15 ENSDART00000155090
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr9_-_32912638 0.15 ENSDART00000110582
family with sequence similarity 160, member A2
chr17_+_23937262 0.15 ENSDART00000113276
si:ch211-189k9.2
chr16_-_28836523 0.15 ENSDART00000108596
ENSDART00000142920
perilipin 6
chr10_-_41352502 0.15 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr5_-_69180587 0.15 ENSDART00000156681
ENSDART00000160753
zgc:171967
chr3_-_20721064 0.15 ENSDART00000193532
speckle-type POZ protein
chr5_-_68244564 0.14 ENSDART00000169350

chr19_+_233143 0.14 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr22_-_37834312 0.14 ENSDART00000076128
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr10_-_43655449 0.14 ENSDART00000099134
myocyte enhancer factor 2ca
chr18_-_46020138 0.14 ENSDART00000027772
phosphate cytidylyltransferase 1, choline, alpha b
chr7_+_33279108 0.14 ENSDART00000084530
coronin, actin binding protein, 2Ba
chr18_+_50276337 0.14 ENSDART00000140352
si:dkey-105e17.1
chr23_-_17509656 0.14 ENSDART00000148423
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr8_-_11833150 0.13 ENSDART00000187861
ENSDART00000064017
Rap guanine nucleotide exchange factor (GEF) 1a
chr7_-_33960170 0.13 ENSDART00000180766
SKI family transcriptional corepressor 1a
chr6_-_40058686 0.13 ENSDART00000103240
urocanate hydratase 1
chr2_-_58075414 0.13 ENSDART00000161920
nectin cell adhesion molecule 4
chr5_-_68058168 0.13 ENSDART00000177026
ring finger protein 167
chr24_+_26017094 0.13 ENSDART00000137851
transferrin receptor 1b
chr16_+_51462620 0.13 ENSDART00000169443
solute carrier family 9 member A1
chr16_-_20707742 0.13 ENSDART00000103630
cAMP responsive element binding protein 5b
chr17_+_25332711 0.13 ENSDART00000082319
transmembrane protein 54a
chr13_-_479129 0.13 ENSDART00000159803
ENSDART00000082127
HEAT repeat containing 5B
chr24_+_42149453 0.13 ENSDART00000128766
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr13_-_27384697 0.13 ENSDART00000146230
potassium voltage-gated channel, KQT-like subfamily, member 5a
chr17_+_1360192 0.13 ENSDART00000184561
SIVA1, apoptosis-inducing factor
chr4_-_2867461 0.13 ENSDART00000160308
phosphodiesterase 3A, cGMP-inhibited
chr18_-_41164277 0.13 ENSDART00000187766
ENSDART00000185375

chr7_+_30725473 0.12 ENSDART00000085716
myotubularin related protein 10
chr18_-_11060548 0.12 ENSDART00000146692
tetraspanin 9a
chr19_+_58954 0.12 ENSDART00000162379
collagen, type XIV, alpha 1b
chr15_-_47929455 0.12 ENSDART00000064462
proteasome subunit alpha 6, like
chr23_+_20518504 0.12 ENSDART00000114246
activity-dependent neuroprotector homeobox b
chr18_+_50276653 0.12 ENSDART00000192120
si:dkey-105e17.1
chr5_-_33460959 0.12 ENSDART00000085636
si:ch211-182d3.1
chr14_+_3074530 0.12 ENSDART00000110721
HMG box domain containing 3
chr18_-_14941840 0.12 ENSDART00000091729
megalencephalic leukoencephalopathy with subcortical cysts 1
chr9_+_28688574 0.12 ENSDART00000101319
zgc:162396
chr10_+_32646402 0.12 ENSDART00000137244
zinc finger and BTB domain containing 21
chr9_+_34380299 0.12 ENSDART00000131705
lysosomal-associated membrane protein 1
chr4_-_9592402 0.12 ENSDART00000114060
cerebral dopamine neurotrophic factor
chr24_+_42149296 0.12 ENSDART00000154231
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr18_+_41772474 0.12 ENSDART00000097547
transient receptor potential cation channel, subfamily C, member 6b
chr12_+_6391243 0.12 ENSDART00000152765
protein kinase, cGMP-dependent, type Ib
chr14_-_24101897 0.12 ENSDART00000143695
cytoplasmic polyadenylation element binding protein 4a
chr16_-_40459104 0.12 ENSDART00000032389
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr22_+_12770877 0.12 ENSDART00000044683
formimidoyltransferase cyclodeaminase
chr19_+_12762887 0.12 ENSDART00000139909
melanocortin 5a receptor
chr3_-_41292569 0.11 ENSDART00000111856
sidekick cell adhesion molecule 1a
chr19_-_8768564 0.11 ENSDART00000170416
si:ch73-350k19.1
chr11_+_30161699 0.11 ENSDART00000190504
cyclin-dependent kinase-like 5
chr14_+_1240604 0.11 ENSDART00000188258
adenosine deaminase domain containing 1 (testis-specific)
chr13_+_3667230 0.11 ENSDART00000131553
ENSDART00000189841
ENSDART00000183554
ENSDART00000018737
QKI, KH domain containing, RNA binding b
chr22_-_14367966 0.11 ENSDART00000188796
low density lipoprotein receptor-related protein 1Ba
chr22_-_16758438 0.11 ENSDART00000132829
PATJ, crumbs cell polarity complex component
chr9_+_46644633 0.11 ENSDART00000160285
solute carrier family 4 (anion exchanger), member 3
chr16_+_4839078 0.11 ENSDART00000150111
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr11_+_30162407 0.11 ENSDART00000190333
ENSDART00000127502
cyclin-dependent kinase-like 5
chr3_-_30061985 0.11 ENSDART00000189583
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3

Network of associatons between targets according to the STRING database.

First level regulatory network of hmx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.3 GO:0035046 pronuclear migration(GO:0035046)
0.1 0.3 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.1 0.3 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.2 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.2 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.4 GO:0071071 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.2 GO:0060688 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.1 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.4 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.8 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0070285 pigment cell development(GO:0070285)
0.0 0.2 GO:0043476 pigment accumulation(GO:0043476)
0.0 0.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.4 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:1903060 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0071387 cellular response to cortisol stimulus(GO:0071387) response to dexamethasone(GO:0071548)
0.0 0.5 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:1904950 negative regulation of protein transport(GO:0051224) negative regulation of establishment of protein localization(GO:1904950)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.4 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.6 GO:0036269 swimming behavior(GO:0036269)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.0 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.4 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0010369 chromocenter(GO:0010369)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0031956 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.1 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.2 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.1 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.0 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation