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PRJNA195909:zebrafish embryo and larva development

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Results for hoxa11b

Z-value: 2.43

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Transcription factors associated with hoxa11b

Gene Symbol Gene ID Gene Info
ENSDARG00000007009 homeobox A11b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa11bdr11_v1_chr16_+_20904754_20904754-0.863.0e-03Click!

Activity profile of hoxa11b motif

Sorted Z-values of hoxa11b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_10014512 4.73 ENSDART00000124341
ENSDART00000191630
zgc:171474
chr19_-_27550768 4.65 ENSDART00000142313
si:dkeyp-46h3.8
chr6_+_28208973 3.92 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
si:ch73-14h10.2
chr14_+_34490445 3.77 ENSDART00000132193
ENSDART00000148044
wingless-type MMTV integration site family, member 8a
chr10_-_10969596 3.61 ENSDART00000092011
exonuclease 3'-5' domain containing 3
chr10_-_10969444 3.30 ENSDART00000138041
exonuclease 3'-5' domain containing 3
chr11_+_18130300 3.22 ENSDART00000169146
zgc:175135
chr20_-_34028967 3.19 ENSDART00000153408
ENSDART00000033817
SCY1-like, kinase-like 3
chr14_+_32918172 3.18 ENSDART00000182867
ligand of numb-protein X 2b
chr21_+_20396858 3.14 ENSDART00000003299
ENSDART00000146615
zgc:103482
chr11_+_18157260 3.10 ENSDART00000144659
zgc:173545
chr7_+_1473929 3.09 ENSDART00000050687
lysophosphatidylcholine acyltransferase 4
chr8_+_45334255 2.99 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr1_-_6028876 2.92 ENSDART00000168117
si:ch1073-345a8.1
chr17_-_4245902 2.81 ENSDART00000151851
growth differentiation factor 3
chr24_-_38083378 2.77 ENSDART00000056381
C-reactive protein 2
chr1_-_53468160 2.57 ENSDART00000143349
zgc:66455
chr2_+_16597011 2.53 ENSDART00000160641
ENSDART00000125413
5'-3' exoribonuclease 1
chr12_+_22674030 2.49 ENSDART00000153254
ENSDART00000152930
cell division cycle associated 9
chr5_-_15283509 2.48 ENSDART00000052712
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr22_-_10440688 2.45 ENSDART00000111962
nucleolar protein 8
chr5_-_37881345 2.45 ENSDART00000084819
Rho GTPase activating protein 35b
chr2_+_6255434 2.45 ENSDART00000139429
zona pellucida glycoprotein 3b
chr6_-_9282080 2.44 ENSDART00000159506
coiled-coil domain containing 14
chr15_+_29024895 2.39 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
chr6_+_4528631 2.39 ENSDART00000122042
ring finger protein 219
chr20_-_51831657 2.35 ENSDART00000165076
melanoma inhibitory activity family, member 3
chr5_-_62940851 2.35 ENSDART00000137052
sperm antigen with calponin homology and coiled-coil domains 1
chr5_+_66132394 2.35 ENSDART00000073892
zgc:114041
chr17_-_25331439 2.32 ENSDART00000155422
ENSDART00000082324
zona pellucida protein C
chr19_-_34995629 2.31 ENSDART00000141704
si:rp71-45k5.2
chr21_-_32781612 2.30 ENSDART00000031028
CCR4-NOT transcription complex, subunit 6a
chr13_+_33462232 2.25 ENSDART00000177841
zgc:136302
chr5_-_1274794 2.23 ENSDART00000167337
ENSDART00000125247
cdkn1a interacting zinc finger protein 1a
chr14_+_15155684 2.22 ENSDART00000167966
zgc:158852
chr23_+_2666944 2.20 ENSDART00000192861

chr16_+_29509133 2.17 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr7_-_51773166 2.07 ENSDART00000054591
bone morphogenetic protein 15
chr11_-_6452444 2.03 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
La ribonucleoprotein domain family, member 6b
chr3_-_3366590 2.02 ENSDART00000109428
ENSDART00000175329
si:dkey-46g23.1
chr14_-_33481428 2.01 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lysosomal-associated membrane protein 2
chr8_+_9699111 2.01 ENSDART00000111853
GRIP1 associated protein 1
chr7_-_69429561 2.01 ENSDART00000127351
ataxin 1-like
chr5_-_32396929 1.99 ENSDART00000023977
F-box and WD repeat domain containing 2
chr17_+_14965570 1.99 ENSDART00000066604
G protein-coupled receptor 137c
chr13_-_4018888 1.98 ENSDART00000058238
tight junction associated protein 1 (peripheral)
chr8_+_13364950 1.98 ENSDART00000159760
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr20_-_51831816 1.98 ENSDART00000060505
melanoma inhibitory activity family, member 3
chr6_-_41138854 1.97 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
solute carrier family 6 member 22, tandem duplicate 1
chr3_-_32873641 1.96 ENSDART00000075277
zgc:113090
chr16_-_21540077 1.91 ENSDART00000078790
serine/threonine kinase 31
chr10_+_6884627 1.90 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr8_+_41037541 1.89 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr12_-_10512911 1.89 ENSDART00000124562
ENSDART00000106163
zgc:152977
chr5_-_57723929 1.87 ENSDART00000144237
grass carp reovirus (GCRV)-induced gene 2p
chr24_+_7495945 1.86 ENSDART00000133525
ENSDART00000182460
ENSDART00000162954
lysine (K)-specific methyltransferase 2Ca
chr2_-_32738535 1.85 ENSDART00000135293
nuclear receptor binding protein 2a
chr16_+_7380463 1.81 ENSDART00000029727
ENSDART00000149086
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr3_-_26183699 1.80 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr5_-_31856681 1.80 ENSDART00000187817
protein kinase N3
chr2_-_26596794 1.78 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr19_+_40069524 1.78 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr8_+_50190742 1.77 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr10_+_15454745 1.76 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbb2 interacting protein
chr2_+_35733335 1.76 ENSDART00000113489
RAS protein activator like 2
chr24_-_10377001 1.75 ENSDART00000144688
ANKH inorganic pyrophosphate transport regulator a
chr21_-_19918286 1.75 ENSDART00000180816
protein phosphatase 1, regulatory subunit 3B
chr3_+_49074008 1.75 ENSDART00000168864
zgc:112146
chr5_-_48664522 1.72 ENSDART00000083229
metallo-beta-lactamase domain containing 2
chr17_-_30521043 1.72 ENSDART00000087111
intersectin 2b
chr16_-_42965192 1.71 ENSDART00000113714
metaxin 1a
chr22_-_11661724 1.71 ENSDART00000025198
methyltransferase like 21A
chr12_-_4249000 1.69 ENSDART00000059298
zgc:92313
chr10_+_6013076 1.68 ENSDART00000167613
ENSDART00000159216
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr7_+_34592526 1.68 ENSDART00000173959
formin homology 2 domain containing 1
chr13_-_25719628 1.67 ENSDART00000135383
si:dkey-192p21.6
chr10_+_15608326 1.67 ENSDART00000188770
zinc finger, AN1-type domain 5b
chr12_-_20616160 1.66 ENSDART00000105362
sorting nexin 11
chr14_-_899170 1.66 ENSDART00000165211
ENSDART00000031992
regulator of G protein signaling 14a
chr6_-_15065376 1.65 ENSDART00000087797
transforming growth factor, beta receptor associated protein 1
chr8_-_39822917 1.65 ENSDART00000067843
zgc:162025
chr2_-_44777592 1.64 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr23_+_6544453 1.64 ENSDART00000005373
SPO11 meiotic protein covalently bound to DSB
chr1_+_18867506 1.63 ENSDART00000184180
ring finger protein 38
chr22_+_10713713 1.62 ENSDART00000122349
hippocampus abundant transcript 1b
chr23_+_43718115 1.62 ENSDART00000149266
ENSDART00000149503
anaphase promoting complex subunit 10
chr1_+_44173245 1.62 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
catenin (cadherin-associated protein), delta 1
chr16_-_10223741 1.62 ENSDART00000188099
si:rp71-15i12.1
chr16_-_36064143 1.62 ENSDART00000158358
ENSDART00000182584
serine/threonine kinase 40
chr18_+_15876385 1.61 ENSDART00000142527
early endosome antigen 1
chr15_-_2841677 1.58 ENSDART00000026145
ENSDART00000180290
angiomotin like 1
chr6_-_42388608 1.57 ENSDART00000049425
Sec61 translocon alpha 1 subunit, like
chr17_-_50040927 1.56 ENSDART00000184304

chr17_-_43594864 1.56 ENSDART00000139980
zinc finger, FYVE domain containing 28
chr5_-_57289872 1.53 ENSDART00000189893
ENSDART00000050957
fer (fps/fes related) tyrosine kinase
chr12_-_33646010 1.53 ENSDART00000111259
transmembrane protein 94
chr23_+_45200481 1.52 ENSDART00000004357
ENSDART00000111126
ENSDART00000193560
ENSDART00000190476
PC4 and SFRS1 interacting protein 1b
chr21_-_22357545 1.52 ENSDART00000134320
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr1_-_9249943 1.52 ENSDART00000055011
zgc:136472
chr20_-_49889111 1.51 ENSDART00000058858
kinesin family member 13Bb
chr5_-_54712159 1.50 ENSDART00000149207
cyclin B1
chr16_-_41717063 1.49 ENSDART00000084610
centrosomal protein 85
chr17_-_2690083 1.48 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr1_+_2321384 1.47 ENSDART00000157662
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr16_-_25368048 1.47 ENSDART00000132445
ribosome binding factor A
chr16_-_28594181 1.46 ENSDART00000059053
ribonuclease P/MRP 38 subunit
chr8_-_51954562 1.46 ENSDART00000132527
ENSDART00000057315
centrosomal protein 78
chr17_+_24318753 1.45 ENSDART00000064083
orthodenticle homeobox 1
chr5_+_3891485 1.45 ENSDART00000129329
ENSDART00000091711
RPA interacting protein
chr6_-_29377092 1.44 ENSDART00000078665
transmembrane protein 131
chr22_+_8753365 1.44 ENSDART00000106086
si:dkey-182g1.2
chr10_+_20392656 1.43 ENSDART00000160803
R3H domain and coiled-coil containing 1
chr13_+_47710434 1.42 ENSDART00000188724
transmembrane protein 87B
chr19_-_10915898 1.41 ENSDART00000163179
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
chr15_-_1843831 1.39 ENSDART00000156718
ENSDART00000154175
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr15_-_16946124 1.39 ENSDART00000154923
huntingtin interacting protein 1
chr22_+_8753092 1.39 ENSDART00000140720
si:dkey-182g1.2
chr17_+_39741926 1.39 ENSDART00000154996
ENSDART00000154599
si:dkey-229e3.2
chr24_+_26402110 1.38 ENSDART00000133684
si:ch211-230g15.5
chr16_+_9400661 1.38 ENSDART00000146174
KIAA0947-like (H. sapiens)
chr13_+_37656278 1.38 ENSDART00000193251
PHD finger protein 3
chr5_-_23715861 1.38 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr7_+_32695954 1.38 ENSDART00000184425
solute carrier family 39 (zinc transporter), member 13
chr5_-_36597612 1.36 ENSDART00000031270
ENSDART00000122098
ras homolog gene family, member Gc
chr15_-_36660789 1.35 ENSDART00000150109
nephrosis 1, congenital, Finnish type (nephrin)
chr7_-_71384391 1.35 ENSDART00000112841
coiled-coil domain containing 149a
chr3_-_36364903 1.35 ENSDART00000028883
guanine nucleotide binding protein (G protein), alpha 13b
chr24_-_26622423 1.35 ENSDART00000182044
TRAF2 and NCK interacting kinase b
chr5_-_68244564 1.34 ENSDART00000169350

chr8_-_13722682 1.34 ENSDART00000142052
si:dkey-258f14.2
chr11_-_36009924 1.34 ENSDART00000189959
ENSDART00000167472
ENSDART00000191211
ENSDART00000191662
ENSDART00000191780
ENSDART00000192622
ENSDART00000179911
inositol 1,4,5-trisphosphate receptor, type 1b
chr15_-_4580763 1.33 ENSDART00000008170
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr23_+_28092083 1.33 ENSDART00000053958
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr5_-_68779747 1.32 ENSDART00000192636
ENSDART00000188039
methylphosphate capping enzyme
chr3_+_3519607 1.32 ENSDART00000150922
CDC42 effector protein (Rho GTPase binding) 1b
chr3_+_52545400 1.32 ENSDART00000184183
solute carrier family 27 (fatty acid transporter), member 1a
chr1_+_494297 1.32 ENSDART00000108579
ENSDART00000146732
basic leucine zipper nuclear factor 1
chr25_-_21031007 1.31 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr13_-_28610965 1.31 ENSDART00000043156
cytochrome P450, family 17, subfamily A, polypeptide 1
chr2_+_12349870 1.31 ENSDART00000134083
Rho GTPase activating protein 21b
chr25_-_34973211 1.31 ENSDART00000045177
cyclin-dependent kinase 10
chr17_-_33707589 1.30 ENSDART00000124788
si:dkey-84k17.2
chr5_+_45140914 1.30 ENSDART00000172702
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_+_12951155 1.30 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr23_+_39963599 1.29 ENSDART00000166539
FYVE and coiled-coil domain containing 1a
chr12_-_13650344 1.28 ENSDART00000124364
ENSDART00000124638
ENSDART00000171929
signal transducer and activator of transcription 5b
chr3_+_60761811 1.27 ENSDART00000053482
TSEN54 tRNA splicing endonuclease subunit
chr22_+_21516689 1.26 ENSDART00000105550
ENSDART00000136374
mesoderm induction early response 1, family member 2
chr20_-_29499363 1.26 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
ribonucleotide reductase M2 polypeptide
chr5_-_29531948 1.26 ENSDART00000098360
arrestin domain containing 1a
chr9_-_2892250 1.26 ENSDART00000140695
cell division cycle associated 7a
chr11_+_35171406 1.25 ENSDART00000110839
MON1 secretory trafficking family member A
chr18_+_26428829 1.25 ENSDART00000190779
ENSDART00000193226
ENSDART00000110746
Bloom syndrome, RecQ helicase-like
chr25_+_16098620 1.25 ENSDART00000142564
ENSDART00000165598
fatty acyl CoA reductase 1
chr23_-_12453700 1.25 ENSDART00000091140
sorting nexin family member 21
chr12_+_16087077 1.24 ENSDART00000141898
zinc finger protein 281b
chr17_+_43595692 1.24 ENSDART00000156271
cilia and flagella associated protein 99
chr17_-_25831569 1.24 ENSDART00000148743
hedgehog acyltransferase
chr8_+_44677569 1.24 ENSDART00000191104
G protein-coupled receptor kinase 5 like
chr9_-_41025062 1.22 ENSDART00000002053
PMS1 homolog 1, mismatch repair system component
chr5_-_11809710 1.22 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
neurofibromin 2a (merlin)
chr7_+_38529263 1.21 ENSDART00000109495
ENSDART00000173804
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr2_+_3823813 1.20 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
Niemann-Pick disease, type C1
chr22_-_10158038 1.20 ENSDART00000047444
RanBP-type and C3HC4-type zinc finger containing 1
chr9_+_21977383 1.20 ENSDART00000135032
si:dkey-57a22.11
chr12_-_11258404 1.20 ENSDART00000149229
si:ch73-30l9.1
chr17_+_17764979 1.20 ENSDART00000105013
alkB homolog 1, histone H2A dioxygenase
chr8_+_23382568 1.19 ENSDART00000129167
microtubule-associated protein, RP/EB family, member 1a
chr11_-_6989598 1.19 ENSDART00000102493
ENSDART00000173242
ENSDART00000172896
zgc:173548
chr24_-_25144441 1.19 ENSDART00000152104
pleckstrin homology-like domain, family B, member 2b
chr16_-_28658341 1.19 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr16_-_32304764 1.19 ENSDART00000143859
ENSDART00000134381
MMS22-like, DNA repair protein
chr19_-_47571797 1.19 ENSDART00000166180
ENSDART00000168134
ribonucleotide reductase M2 polypeptide
chr3_-_26184018 1.19 ENSDART00000191604
si:ch211-11k18.4
chr12_+_30788912 1.19 ENSDART00000160422
aldehyde dehydrogenase 18 family, member A1
chr17_-_31611692 1.18 ENSDART00000141480
si:dkey-170l10.1
chr10_+_32050906 1.18 ENSDART00000137373
si:ch211-266i6.3
chr22_-_24818066 1.18 ENSDART00000143443
vitellogenin 6
chr8_-_12432604 1.18 ENSDART00000133350
ENSDART00000140699
ENSDART00000101174
TNF receptor-associated factor 1
chr21_-_36453594 1.18 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8
chr2_+_54086436 1.18 ENSDART00000174581

chr11_+_11303458 1.17 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
chr3_+_35406998 1.17 ENSDART00000102994
retinoblastoma binding protein 6
chr13_+_11073282 1.16 ENSDART00000114911
ENSDART00000182462
ENSDART00000148100
ENSDART00000137816
ENSDART00000134888
ENSDART00000131320
serologically defined colon cancer antigen 8
chr17_-_10043273 1.16 ENSDART00000156078
bromodomain adjacent to zinc finger domain, 1A
chr16_+_13993285 1.16 ENSDART00000139130
ENSDART00000130353
si:dkey-85k15.7
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr10_-_1276046 1.15 ENSDART00000169779
PDZ and LIM domain 5b
chr3_+_26244353 1.15 ENSDART00000103733
ATPase family, AAA domain containing 5a
chr16_-_32727199 1.15 ENSDART00000137232
ubiquitin specific peptidase 45
chr8_-_40442979 1.14 ENSDART00000157698
ENSDART00000192657
TBC1 domain family, member 10Aa
chr11_-_18283886 1.14 ENSDART00000019248
STIM activating enhance
chr14_+_45028062 1.14 ENSDART00000184717
ENSDART00000185481
ATPase phospholipid transporting 8A1
chr16_+_39146696 1.13 ENSDART00000121756
ENSDART00000084381
syntabulin (syntaxin-interacting)
chr18_+_18000695 1.13 ENSDART00000146898
si:ch211-212o1.2
chr13_+_39277178 1.13 ENSDART00000113259
si:dkey-85a20.4
chr1_-_20068155 1.12 ENSDART00000102993
methyltransferase like 14
chr19_+_9111550 1.12 ENSDART00000088336
SET domain, bifurcated 1a
chr25_-_15268443 1.11 ENSDART00000151827
coiled-coil domain containing 73
chr9_+_34952203 1.11 ENSDART00000121828
ENSDART00000142347
transcription factor Dp-1, a
chr13_-_2981472 1.11 ENSDART00000184820

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa11b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.6 3.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.6 1.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 2.8 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.6 1.7 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.6 1.7 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.6 1.7 GO:0097065 anterior head development(GO:0097065)
0.5 1.6 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.5 2.1 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.5 2.0 GO:0099563 modification of synaptic structure(GO:0099563)
0.5 2.3 GO:0071071 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.4 1.3 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.4 1.3 GO:0030238 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.4 2.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 1.3 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.4 1.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 1.2 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.4 1.5 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.4 3.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.3 1.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.3 1.0 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 1.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.3 2.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 3.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 1.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.3 0.9 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.3 1.1 GO:0060074 synapse maturation(GO:0060074)
0.3 4.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.3 1.1 GO:0060019 radial glial cell differentiation(GO:0060019)
0.3 2.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.3 1.6 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.3 1.9 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.3 0.8 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.3 1.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 1.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 1.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 1.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.3 1.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 1.0 GO:0042308 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) regulation of protein localization to nucleus(GO:1900180) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.2 1.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 0.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 1.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.2 4.3 GO:0035459 cargo loading into vesicle(GO:0035459)
0.2 1.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 1.6 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 0.9 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.2 1.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.2 1.1 GO:0097094 regulation of osteoblast proliferation(GO:0033688) craniofacial suture morphogenesis(GO:0097094)
0.2 1.3 GO:0016572 histone phosphorylation(GO:0016572)
0.2 1.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.2 1.1 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.2 1.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 1.1 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.2 1.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 1.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 1.0 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.6 GO:0034214 protein hexamerization(GO:0034214)
0.2 1.4 GO:0048478 replication fork protection(GO:0048478)
0.2 1.8 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 0.6 GO:0060907 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2 1.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 0.8 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.2 1.3 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.7 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 0.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 2.0 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.2 1.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 2.2 GO:0070828 heterochromatin organization(GO:0070828)
0.2 0.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 2.7 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.2 0.9 GO:0019860 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.2 0.7 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 2.8 GO:0016075 rRNA catabolic process(GO:0016075)
0.2 0.8 GO:0007624 ultradian rhythm(GO:0007624)
0.2 1.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 0.5 GO:0042256 mature ribosome assembly(GO:0042256)
0.2 2.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 1.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 1.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 1.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 1.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.2 0.6 GO:0021557 oculomotor nerve development(GO:0021557)
0.2 2.4 GO:0060325 face morphogenesis(GO:0060325)
0.2 2.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.2 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 3.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.9 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 1.1 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 0.4 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 1.9 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 0.8 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.3 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 2.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.9 GO:0035627 ceramide transport(GO:0035627)
0.1 1.8 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 3.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 2.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.3 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.5 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.1 2.1 GO:0031297 replication fork processing(GO:0031297)
0.1 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 1.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.5 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.5 GO:0060155 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.1 0.7 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 2.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.4 GO:0034969 histone arginine methylation(GO:0034969)
0.1 1.0 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.9 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.3 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 2.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0039529 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 0.5 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.6 GO:0015809 arginine transport(GO:0015809)
0.1 0.4 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.8 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 2.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.3 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 1.7 GO:0008354 germ cell migration(GO:0008354)
0.1 1.4 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.7 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.7 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.7 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.8 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 1.7 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 2.9 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 1.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 1.9 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 1.0 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 2.6 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.9 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 0.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.4 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 0.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 4.7 GO:0034504 protein localization to nucleus(GO:0034504)
0.1 1.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.9 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.4 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 1.1 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.1 1.1 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 1.1 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 4.4 GO:0007030 Golgi organization(GO:0007030)
0.1 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 0.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.4 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 0.5 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 1.2 GO:0006298 mismatch repair(GO:0006298)
0.1 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.3 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 1.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 1.4 GO:0016601 Rac protein signal transduction(GO:0016601) regulation of neutrophil migration(GO:1902622)
0.0 3.3 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 1.0 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.2 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 2.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.9 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) histone mRNA metabolic process(GO:0008334)
0.0 0.7 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0070228 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.8 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 1.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.8 GO:1901661 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.0 1.0 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.8 GO:0060969 negative regulation of chromatin silencing(GO:0031936) negative regulation of gene silencing(GO:0060969)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.9 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.3 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 2.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 3.4 GO:0000819 sister chromatid segregation(GO:0000819)
0.0 1.1 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 6.5 GO:0016197 endosomal transport(GO:0016197)
0.0 0.6 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 1.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.5 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.6 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.2 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 1.5 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.4 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.8 GO:0009648 photoperiodism(GO:0009648)
0.0 1.4 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.2 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.5 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 2.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 1.5 GO:0018210 peptidyl-threonine modification(GO:0018210)
0.0 1.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 0.7 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.3 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 3.2 GO:0032259 methylation(GO:0032259)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.4 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 2.0 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 1.1 GO:0042113 B cell activation(GO:0042113)
0.0 1.5 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.8 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) histone H3-K4 demethylation(GO:0034720) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 6.1 GO:0006644 phospholipid metabolic process(GO:0006644)
0.0 0.7 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.4 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 1.6 GO:0008033 tRNA processing(GO:0008033)
0.0 0.5 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.4 GO:0016072 rRNA processing(GO:0006364) rRNA metabolic process(GO:0016072)
0.0 1.6 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.8 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.4 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.5 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 2.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.4 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.6 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.5 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.0 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.5 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 2.6 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.7 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0032233 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.8 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 0.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0046887 positive regulation of hormone secretion(GO:0046887)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0097189 apoptotic body(GO:0097189)
0.7 2.0 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.5 1.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.4 2.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.4 1.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 1.4 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 2.6 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.3 1.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.3 0.9 GO:0034457 Mpp10 complex(GO:0034457)
0.3 1.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 1.6 GO:0005784 Sec61 translocon complex(GO:0005784)
0.2 1.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 1.0 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.2 1.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 4.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 0.9 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.2 1.5 GO:0001650 fibrillar center(GO:0001650) multimeric ribonuclease P complex(GO:0030681)
0.2 2.0 GO:0036449 microtubule minus-end(GO:0036449)
0.2 1.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 2.1 GO:0035101 FACT complex(GO:0035101)
0.2 1.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 1.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 0.5 GO:0031213 RSF complex(GO:0031213)
0.2 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 0.8 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.2 0.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 3.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.3 GO:0031526 brush border membrane(GO:0031526)
0.1 4.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.7 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.4 GO:0030689 Noc complex(GO:0030689)
0.1 1.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0017177 glucosidase II complex(GO:0017177)
0.1 1.5 GO:0030904 retromer complex(GO:0030904)
0.1 1.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.2 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.9 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.8 GO:0000938 GARP complex(GO:0000938)
0.1 1.2 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.5 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.4 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 3.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.4 GO:0055087 Ski complex(GO:0055087)
0.1 1.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 3.5 GO:0031941 filamentous actin(GO:0031941)
0.1 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.1 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.9 GO:0043186 P granule(GO:0043186)
0.1 2.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 3.6 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.3 GO:0008278 cohesin complex(GO:0008278)
0.1 2.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.8 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.8 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.0 GO:0032039 integrator complex(GO:0032039)
0.0 2.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.1 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.4 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 3.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.3 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 5.3 GO:0005813 centrosome(GO:0005813)
0.0 5.7 GO:0005730 nucleolus(GO:0005730)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 3.1 GO:0005635 nuclear envelope(GO:0005635)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 1.2 GO:0000228 nuclear chromosome(GO:0000228)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.2 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.6 1.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.6 1.7 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.5 3.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.5 1.4 GO:0004061 arylformamidase activity(GO:0004061)
0.4 1.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.4 4.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.4 2.0 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.4 2.0 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.4 1.2 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.4 1.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4 1.1 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.4 1.5 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.4 1.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.4 1.1 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.4 1.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.3 1.0 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.3 1.3 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.3 2.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 2.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 1.2 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.3 2.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.3 0.9 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.3 1.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 1.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.3 1.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3 1.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 2.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 1.7 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.2 1.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 1.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 3.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 3.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.2 1.1 GO:0043531 ADP binding(GO:0043531)
0.2 1.1 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.2 1.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 1.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 2.3 GO:0005537 mannose binding(GO:0005537)
0.2 1.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 0.9 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.2 0.9 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.2 8.1 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.2 0.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 0.7 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.2 1.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.2 1.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.5 GO:0030882 lipid antigen binding(GO:0030882)
0.2 1.6 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.2 0.7 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 1.9 GO:0043495 protein anchor(GO:0043495)
0.2 1.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 0.6 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 0.6 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 3.0 GO:0048038 quinone binding(GO:0048038)
0.1 1.0 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 2.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.8 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 0.8 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.6 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 1.8 GO:2001069 glycogen binding(GO:2001069)
0.1 0.7 GO:1903924 estradiol binding(GO:1903924)
0.1 0.5 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 1.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 1.5 GO:0070628 proteasome binding(GO:0070628)
0.1 0.4 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 0.7 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.8 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 0.9 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.3 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 2.1 GO:0019894 kinesin binding(GO:0019894)
0.1 1.9 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 1.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 3.8 GO:0005109 frizzled binding(GO:0005109)
0.1 1.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 2.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.5 GO:0030552 cAMP binding(GO:0030552)
0.1 2.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 2.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 5.9 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.8 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 1.0 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 0.5 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.2 GO:0070513 death domain binding(GO:0070513)
0.1 1.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.0 GO:0002039 p53 binding(GO:0002039)
0.1 1.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.9 GO:0031386 protein tag(GO:0031386)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0015923 mannosidase activity(GO:0015923)
0.0 1.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 8.6 GO:0042393 histone binding(GO:0042393)
0.0 1.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 2.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.5 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.5 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 4.4 GO:0004518 nuclease activity(GO:0004518)
0.0 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.7 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 1.2 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.9 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.7 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.2 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 12.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.7 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 1.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.5 GO:0008134 transcription factor binding(GO:0008134)
0.0 5.4 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.4 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 2.8 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 1.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 4.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 3.6 PID FOXO PATHWAY FoxO family signaling
0.1 1.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 5.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.5 PID AURORA B PATHWAY Aurora B signaling
0.1 4.7 PID E2F PATHWAY E2F transcription factor network
0.1 2.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 1.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 3.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 3.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 2.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 2.8 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 1.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 3.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 3.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 0.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.0 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.0 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.1 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.2 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 2.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.1 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation