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PRJNA195909:zebrafish embryo and larva development

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Results for mafk

Z-value: 1.10

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Transcription factors associated with mafk

Gene Symbol Gene ID Gene Info
ENSDARG00000100947 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafkdr11_v1_chr3_-_42967698_42967698-0.343.8e-01Click!

Activity profile of mafk motif

Sorted Z-values of mafk motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_30615901 2.80 ENSDART00000147769
si:ch211-117m20.5
chr5_-_67471375 2.72 ENSDART00000147009
si:dkey-251i10.2
chr3_-_32818607 2.22 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr9_-_22076368 2.09 ENSDART00000128486
crystallin, gamma M2a
chr12_-_4683325 1.84 ENSDART00000152771
si:ch211-255p10.3
chr16_-_16182319 1.72 ENSDART00000103815
stathmin 2a
chr3_-_26017592 1.66 ENSDART00000030890
heme oxygenase 1a
chr19_+_7567763 1.64 ENSDART00000140411
S100 calcium binding protein A11
chr3_-_26017831 1.55 ENSDART00000179982
heme oxygenase 1a
chr2_-_2020044 1.37 ENSDART00000024135
tubulin, beta 2A class IIa
chr22_-_26595027 1.30 ENSDART00000184162

chr9_-_22345500 1.29 ENSDART00000101802
crystallin, gamma M2f
chr19_+_31771270 1.20 ENSDART00000147474
stathmin 2b
chr11_-_24681292 1.17 ENSDART00000089601
olfactomedin-like 3b
chr14_+_34780886 1.02 ENSDART00000130469
ENSDART00000188806
ENSDART00000172924
ENSDART00000173266
ENSDART00000166377
ENSDART00000173371
SH3 domain and tetratricopeptide repeats 2
chr16_-_43026273 1.00 ENSDART00000156820
ENSDART00000189080
si:dkey-7j14.5
chr16_+_20915319 0.94 ENSDART00000079383
homeobox A9b
chr24_-_40731305 0.89 ENSDART00000172073

chr22_-_13350240 0.88 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
chr6_+_12853655 0.85 ENSDART00000156341
family with sequence similarity 117, member Ba
chr20_+_34326874 0.84 ENSDART00000061659
influenza virus NS1A binding protein a
chr4_-_16334362 0.83 ENSDART00000101461
epiphycan
chr9_+_41103127 0.83 ENSDART00000000250
solute carrier family 40 (iron-regulated transporter), member 1
chr11_+_26609110 0.82 ENSDART00000042322
microtubule-associated protein 1 light chain 3 alpha
chr19_-_6385594 0.82 ENSDART00000104950
ATPase Na+/K+ transporting subunit alpha 3a
chr14_+_11457500 0.78 ENSDART00000169202
si:ch211-153b23.5
chr17_-_12389259 0.77 ENSDART00000185724
synaptosomal-associated protein, 25b
chr13_+_2908764 0.75 ENSDART00000162362
wu:fj16a03
chr21_+_20383837 0.75 ENSDART00000026430
heat shock protein, alpha-crystallin-related, b11
chr20_-_39103119 0.75 ENSDART00000143379
regulator of calcineurin 2
chr23_-_19500559 0.75 ENSDART00000177414
ENSDART00000145898
ankyrin repeat and SOCS box containing 14b
chr12_+_48216662 0.74 ENSDART00000187369
leucine rich repeat containing 20
chr11_-_18253111 0.74 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr11_-_3334248 0.73 ENSDART00000154314
ENSDART00000121861
peripherin
chr14_-_3381303 0.73 ENSDART00000171601
im:7150988
chr16_-_43025885 0.72 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr14_+_30279391 0.70 ENSDART00000172794
fibrinogen-like 1
chr11_-_25418856 0.69 ENSDART00000013714
GATA binding protein 1a
chr11_+_2198831 0.69 ENSDART00000160515
homeobox C6b
chr20_-_31905968 0.67 ENSDART00000142806
syntaxin binding protein 5a (tomosyn)
chr11_+_13630107 0.67 ENSDART00000172220
si:ch211-1a19.3
chr9_-_23118350 0.66 ENSDART00000020884
LY6/PLAUR domain containing 6
chr14_-_4076480 0.66 ENSDART00000059231
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr16_-_21785261 0.65 ENSDART00000078858
si:ch73-86n18.1
chr23_+_36118738 0.65 ENSDART00000139319
homeobox C5a
chr5_+_29820266 0.64 ENSDART00000146331
ENSDART00000098315
F11 receptor, tandem duplicate 2
chr25_-_173165 0.63 ENSDART00000193594

chr1_+_19303241 0.63 ENSDART00000129970
si:dkeyp-118a3.2
chr3_-_21280373 0.63 ENSDART00000003939
synaptogyrin 1a
chr22_+_38192568 0.63 ENSDART00000126323
ceruloplasmin
chr12_+_2446837 0.62 ENSDART00000112032
si:dkey-191m6.4
chr1_-_20928772 0.61 ENSDART00000078277
methylsterol monooxygenase 1
chr7_+_39386982 0.60 ENSDART00000146702
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr22_+_28446557 0.60 ENSDART00000089546
ABI family, member 3 (NESH) binding protein b
chr22_+_28446365 0.60 ENSDART00000189359
ABI family, member 3 (NESH) binding protein b
chr4_-_5291256 0.59 ENSDART00000150864
si:ch211-214j24.9
chr23_-_29376859 0.58 ENSDART00000146411
somatostatin 6
chr4_-_2545310 0.57 ENSDART00000150619
ENSDART00000140760
E2F transcription factor 7
chr1_-_25966068 0.57 ENSDART00000137869
ENSDART00000134192
synaptopodin 2b
chr20_-_35578435 0.57 ENSDART00000142444
adhesion G protein-coupled receptor F6
chr3_+_23752150 0.56 ENSDART00000146636
homeobox B2a
chr22_-_13857729 0.56 ENSDART00000177971
S100 calcium binding protein, beta (neural)
chr24_-_37680917 0.56 ENSDART00000131342
ankyrin repeat and sterile alpha motif domain containing 3
chr7_+_63325819 0.56 ENSDART00000085612
ENSDART00000161436
protocadherin 7b
chr23_-_35756115 0.54 ENSDART00000043429
junctophilin 2
chr7_+_69841017 0.54 ENSDART00000169107

chr1_+_59090743 0.54 ENSDART00000100199
microfibril associated protein 4
chr2_-_16562505 0.53 ENSDART00000156406
ATPase Na+/K+ transporting subunit beta 3a
chr23_-_27571667 0.53 ENSDART00000008174
phosphofructokinase, muscle a
chr11_+_37265692 0.51 ENSDART00000184691
interleukin 17 receptor C
chr23_+_3731375 0.51 ENSDART00000141782
small integral membrane protein 29
chr8_-_17516448 0.51 ENSDART00000100667
v-ski avian sarcoma viral oncogene homolog a
chr16_-_48673938 0.50 ENSDART00000156969
notch homolog, like
chr13_+_35746440 0.50 ENSDART00000187859
G protein-coupled receptor 75
chr13_-_23007813 0.50 ENSDART00000057638
hexokinase 1
chr1_-_40227166 0.50 ENSDART00000146680
si:ch211-113e8.3
chr3_+_32557615 0.49 ENSDART00000151608
paired box 10
chr24_+_41940299 0.49 ENSDART00000022349
erythrocyte membrane protein band 4.1-like 3a
chr23_+_17865953 0.49 ENSDART00000014723
ENSDART00000140302
ENSDART00000144800
nascent polypeptide-associated complex alpha subunit
chr19_+_37701450 0.49 ENSDART00000087694
thrombospondin, type I, domain containing 7Aa
chr1_+_55137943 0.49 ENSDART00000138070
ENSDART00000150510
ENSDART00000133472
ENSDART00000136378
myoglobin
chr14_-_17588345 0.49 ENSDART00000143486
selenoprotein T, 2
chr19_-_10881486 0.48 ENSDART00000168852
ENSDART00000160438
proteasome 26S subunit, non-ATPase 4
proteasome 26S subunit, non-ATPase 4a
chr6_+_41463786 0.48 ENSDART00000065006
twinfilin actin-binding protein 2a
chr3_+_7617353 0.48 ENSDART00000165551
zgc:109949
chr20_-_39271844 0.48 ENSDART00000192708
clusterin
chr19_+_19786117 0.48 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr22_-_11724563 0.48 ENSDART00000190796
ENSDART00000184744
keratin 222
chr8_-_7847921 0.47 ENSDART00000188094
zgc:113363
chr22_+_28337204 0.47 ENSDART00000163352
interphotoreceptor matrix proteoglycan 2b
chr11_-_10770053 0.47 ENSDART00000179213
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr11_+_13629528 0.47 ENSDART00000186509
si:ch211-1a19.3
chr16_+_14033121 0.47 ENSDART00000135844
RUN and SH3 domain containing 1
chr19_-_32641725 0.47 ENSDART00000165006
ENSDART00000188185
hippocalcin
chr5_-_44843738 0.46 ENSDART00000003926
fructose-1,6-bisphosphatase 1a
chr5_-_25582721 0.46 ENSDART00000123986
annexin A1a
chr22_-_5006801 0.46 ENSDART00000106166
retinal homeobox gene 1
chr5_-_71460556 0.45 ENSDART00000108804
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr22_+_6677429 0.44 ENSDART00000147482
si:ch211-209l18.2
chr7_-_52842007 0.44 ENSDART00000182710
microtubule-associated protein 1Aa
chr18_-_5692292 0.44 ENSDART00000121503
complexin 3b
chr19_+_8506178 0.44 ENSDART00000189689
S100 calcium binding protein A10a
chr21_+_45819662 0.44 ENSDART00000193362
ENSDART00000184255
paired-like homeodomain 1
chr12_-_1951233 0.43 ENSDART00000005676
ENSDART00000127937
SRY (sex determining region Y)-box 9a
chr2_+_9821757 0.43 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr20_-_19422496 0.43 ENSDART00000143658
si:ch211-278j3.3
chr7_-_15413019 0.43 ENSDART00000172147
si:ch211-106j24.1
chr1_+_41588170 0.43 ENSDART00000139175
si:dkey-56e3.2
chr21_-_23110841 0.42 ENSDART00000147896
ENSDART00000003076
ENSDART00000184925
ENSDART00000190386
ubiquitin specific peptidase 28
chr21_-_41025340 0.42 ENSDART00000148231
PLAC8-like 1
chr18_-_17020231 0.42 ENSDART00000129146
TBC1 domain family, member 15
chr14_-_30960470 0.42 ENSDART00000129989
si:ch211-191o15.6
chr7_+_20298333 0.42 ENSDART00000023089
ENSDART00000131019
acyl-CoA dehydrogenase very long chain
chr4_-_73787702 0.41 ENSDART00000136328
ENSDART00000150546
si:dkey-262g12.3
chr1_-_25966411 0.41 ENSDART00000193375
synaptopodin 2b
chr1_+_59090583 0.41 ENSDART00000150658
microfibril associated protein 4
chr23_+_19813677 0.41 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr9_-_23253870 0.40 ENSDART00000143657
ENSDART00000169911
aminocarboxymuconate semialdehyde decarboxylase
chr16_+_9779680 0.40 ENSDART00000154253
zgc:92912
chr16_-_17162843 0.40 ENSDART00000089386
intermediate filament family orphan 1b
chr23_-_9965148 0.39 ENSDART00000137308
plexin b1a
chr7_-_50917255 0.39 ENSDART00000022918
ankyrin repeat domain 46b
chr8_+_39511932 0.39 ENSDART00000113511
leucine zipper, putative tumor suppressor 1
chr23_+_13814978 0.39 ENSDART00000090864
leiomodin 3 (fetal)
chr2_+_25278107 0.39 ENSDART00000131977
protein phosphatase 2, regulatory subunit B'', alpha
chr12_+_38556462 0.39 ENSDART00000021069
ENSDART00000145377
ribosomal protein L38
chr7_+_57109214 0.38 ENSDART00000135068
ENSDART00000098412
enolase superfamily member 1
chr24_-_42148339 0.38 ENSDART00000112680
regulator of microtubule dynamics 1
chr19_+_26828502 0.38 ENSDART00000183654
ENSDART00000126006
ENSDART00000185341

chr3_-_18030938 0.38 ENSDART00000013540
si:ch73-141c7.1
chr6_+_41096058 0.38 ENSDART00000028373
FK506 binding protein 5
chr19_-_7420867 0.37 ENSDART00000081741
RAB25, member RAS oncogene family a
chr19_-_10243148 0.37 ENSDART00000148073
shisa family member 7
chr7_+_17229980 0.37 ENSDART00000184910
solute carrier family 6 (neurotransmitter transporter), member 5
chr2_+_9552456 0.37 ENSDART00000056896
DnaJ (Hsp40) homolog, subfamily B, member 4
chr25_-_15214161 0.36 ENSDART00000031499
wilms tumor 1a
chr23_+_14217508 0.36 ENSDART00000143618
baculoviral IAP repeat containing 7
chr15_+_37559570 0.36 ENSDART00000085522
heat shock protein, alpha-crystallin-related, b6
chr4_+_13568469 0.36 ENSDART00000171235
ENSDART00000136152
calumenin a
chr9_-_24242592 0.36 ENSDART00000039399
caveolae associated protein 2a
chr17_+_45413324 0.36 ENSDART00000124911
ezrin a
chr10_+_26747755 0.35 ENSDART00000100329
coagulation factor IXb
chr5_+_66355153 0.35 ENSDART00000082745
si:ch211-261c8.5
chr19_-_17658160 0.34 ENSDART00000151766
ENSDART00000170790
ENSDART00000186678
ENSDART00000188045
ENSDART00000176980
ENSDART00000166313
ENSDART00000188589
thyroid hormone receptor beta
chr8_-_34052019 0.34 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pre-B-cell leukemia homeobox 3b
chr19_+_8144556 0.34 ENSDART00000027274
ENSDART00000147218
ephrin-A3a
chr17_+_15413412 0.34 ENSDART00000149871
connexin 40.8
chr7_+_22657566 0.34 ENSDART00000141048
plac8 onzin related protein 5
chr25_+_16945348 0.34 ENSDART00000016591
fibroblast growth factor 6a
chr21_-_11820379 0.33 ENSDART00000126640
si:dkey-6b12.5
chr12_-_4346085 0.33 ENSDART00000112433
carbonic anhydrase XV c
chr20_-_1314537 0.33 ENSDART00000144288
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr21_+_5993188 0.33 ENSDART00000048399
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr10_+_4235998 0.33 ENSDART00000169328
phospholipid phosphatase related 1
chr2_+_9822319 0.33 ENSDART00000144078
ENSDART00000144371
annexin A13, like
chr16_-_12319822 0.32 ENSDART00000127453
ENSDART00000184526
transient receptor potential cation channel, subfamily V, member 6
chr21_+_9576176 0.32 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mitogen-activated protein kinase 10
chr5_-_27867657 0.32 ENSDART00000112495
transcriptional and immune response regulator a
chr16_+_13855039 0.32 ENSDART00000113764
ENSDART00000143983
zgc:174888
chr7_+_20475788 0.32 ENSDART00000171155
si:dkey-19b23.13
chr19_-_41404870 0.32 ENSDART00000167772
SEM1, 26S proteasome complex subunit
chr22_-_16997246 0.31 ENSDART00000090242
nuclear factor I/A
chr11_-_23501467 0.31 ENSDART00000169066
pleckstrin homology domain containing, family A member 6
chr22_-_31059670 0.31 ENSDART00000022445
cullin-associated and neddylation-dissociated 2 (putative)
chr16_+_14029283 0.31 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr21_-_39327223 0.30 ENSDART00000115097
apoptosis-inducing factor, mitochondrion-associated, 5
chr23_-_18286822 0.30 ENSDART00000136672
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1a
chr3_-_12970418 0.30 ENSDART00000158747
platelet-derived growth factor alpha polypeptide b
chr20_+_28245164 0.30 ENSDART00000103320
delta-like 4 (Drosophila)
chr1_-_46989650 0.30 ENSDART00000129072
ENSDART00000150507
si:dkey-22n8.3
chr8_-_34051548 0.30 ENSDART00000105204
pre-B-cell leukemia homeobox 3b
chr11_-_40101246 0.30 ENSDART00000161083
tumor necrosis factor receptor superfamily, member 9b
chr6_-_35446110 0.29 ENSDART00000058773
regulator of G protein signaling 16
chr3_-_30158395 0.29 ENSDART00000103502
si:ch211-152f23.5
chr22_+_1049367 0.29 ENSDART00000065380
calcium/calmodulin-dependent protein kinase IGa
chr24_-_16917086 0.29 ENSDART00000110715
carboxymethylenebutenolidase homolog (Pseudomonas)
chr1_-_43905252 0.29 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr16_-_27640995 0.28 ENSDART00000019658
NAC alpha domain containing
chr5_+_65946222 0.28 ENSDART00000190969
ENSDART00000161578
myomaker, myoblast fusion factor
chr20_+_28245587 0.28 ENSDART00000191703
delta-like 4 (Drosophila)
chr21_-_20832482 0.28 ENSDART00000191928
complement component 6
chr7_+_756942 0.28 ENSDART00000152224
zgc:63470
chr23_+_23918421 0.27 ENSDART00000046951
protein tyrosine phosphatase, non-receptor type 11, b
chr10_-_322769 0.27 ENSDART00000165244
v-akt murine thymoma viral oncogene homolog 2, like
chr14_-_17306261 0.27 ENSDART00000191747
janus kinase and microtubule interacting protein 1
chr5_+_37087583 0.27 ENSDART00000049900
transgelin 2
chr16_-_17162485 0.27 ENSDART00000123011
intermediate filament family orphan 1b
chr22_+_28337429 0.27 ENSDART00000166177
interphotoreceptor matrix proteoglycan 2b
chr19_-_32600823 0.27 ENSDART00000134149
ENSDART00000187858
zgc:91944
chr20_-_1314355 0.26 ENSDART00000152436
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr7_-_52842605 0.26 ENSDART00000083002
microtubule-associated protein 1Aa
chr3_+_46444625 0.26 ENSDART00000108686
si:ch211-66e2.3
chr7_+_62004048 0.26 ENSDART00000181818
small integral membrane protein 20
chr2_-_5135125 0.26 ENSDART00000164039
prothymosin, alpha b
chr5_-_63109232 0.26 ENSDART00000115128
ubiquitin specific peptidase 2b
chr21_-_5393125 0.25 ENSDART00000146061
proteasome 26S subunit, non-ATPase 5
chr21_-_25756119 0.25 ENSDART00000002341
claudin c
chr18_-_14937211 0.25 ENSDART00000141893
megalencephalic leukoencephalopathy with subcortical cysts 1
chr3_+_32142382 0.25 ENSDART00000133035
synaptotagmin Va
chr3_+_31177972 0.25 ENSDART00000185954
C-type lectin domain containing 19A

Network of associatons between targets according to the STRING database.

First level regulatory network of mafk

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.2 0.7 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.8 GO:0010039 response to iron ion(GO:0010039)
0.2 0.6 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.2 0.7 GO:0030224 monocyte differentiation(GO:0030224)
0.2 0.5 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.1 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 2.5 GO:0006825 copper ion transport(GO:0006825)
0.1 0.6 GO:0042023 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 0.7 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 1.6 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.4 GO:0061032 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.3 GO:0042706 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.3 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.6 GO:0043092 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.1 0.5 GO:0033034 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 3.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.2 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.1 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.3 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 0.4 GO:0046874 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.2 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.5 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.7 GO:0031033 myosin filament organization(GO:0031033)
0.1 1.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.5 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.6 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.8 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.5 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.2 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.4 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.0 0.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.5 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 3.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.3 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.1 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.0 0.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0008206 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.1 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.8 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.8 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.4 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.8 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.4 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.2 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.2 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.0 GO:0090248 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.0 0.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0003207 cardiac chamber formation(GO:0003207)
0.0 0.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.4 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.1 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:0002263 cell activation involved in immune response(GO:0002263)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 2.9 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:1990246 uniplex complex(GO:1990246)
0.0 0.5 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0005861 troponin complex(GO:0005861)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 0.0 GO:0014704 intercalated disc(GO:0014704)
0.0 1.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.4 1.8 GO:0016531 copper chaperone activity(GO:0016531)
0.2 0.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.7 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.6 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.5 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 2.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 3.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.7 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0051800 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785) tropomyosin binding(GO:0005523)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade