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PRJNA195909:zebrafish embryo and larva development

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Results for mixl1+mxtx1+sebox

Z-value: 0.98

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Transcription factors associated with mixl1+mxtx1+sebox

Gene Symbol Gene ID Gene Info
ENSDARG00000042526 SEBOX homeobox
ENSDARG00000069252 Mix paired-like homeobox
ENSDARG00000069382 mix-type homeobox gene 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mixl1dr11_v1_chr20_-_43723860_437238600.491.8e-01Click!
mxtx1dr11_v1_chr13_-_21660203_216602030.422.6e-01Click!
seboxdr11_v1_chr5_+_67371650_67371650-0.304.3e-01Click!

Activity profile of mixl1+mxtx1+sebox motif

Sorted Z-values of mixl1+mxtx1+sebox motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 3.96 ENSDART00000021620
claudin d
chr10_+_6884627 2.69 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr8_+_45334255 2.50 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr20_-_23426339 2.34 ENSDART00000004625
zygote arrest 1
chr10_-_21362320 2.23 ENSDART00000189789
avidin
chr10_-_21362071 2.21 ENSDART00000125167
avidin
chr24_+_12835935 2.07 ENSDART00000114762
nanog homeobox
chr1_-_18811517 2.05 ENSDART00000142026
si:dkey-167i21.2
chr12_-_14143344 2.00 ENSDART00000152742
bucky ball 2-like
chr16_-_29387215 1.99 ENSDART00000148787
S100 calcium binding protein A1
chr18_-_40708537 1.89 ENSDART00000077577
si:ch211-132b12.8
chr2_+_6253246 1.82 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr1_-_55248496 1.74 ENSDART00000098615
nanos homolog 3
chr14_+_34492288 1.68 ENSDART00000144301
wingless-type MMTV integration site family, member 8a
chr10_-_25217347 1.56 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr14_+_34490445 1.53 ENSDART00000132193
ENSDART00000148044
wingless-type MMTV integration site family, member 8a
chr10_+_6884123 1.47 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr24_+_1023839 1.46 ENSDART00000082526
zgc:111976
chr7_-_51773166 1.41 ENSDART00000054591
bone morphogenetic protein 15
chr14_-_33481428 1.39 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lysosomal-associated membrane protein 2
chr9_+_29548195 1.29 ENSDART00000176057
ring finger protein 17
chr11_-_1550709 1.27 ENSDART00000110097
si:ch73-303b9.1
chr16_+_29509133 1.22 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr14_-_8940499 1.11 ENSDART00000129030
zgc:153681
chr1_+_35985813 1.06 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
chr6_+_40922572 1.05 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr17_+_16046132 1.05 ENSDART00000155005
si:ch73-204p21.2
chr4_+_11723852 1.02 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr22_+_4488454 1.02 ENSDART00000170620
cortexin 1
chr16_-_42056137 1.00 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr19_+_15441022 0.97 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr8_+_41037541 0.97 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr23_-_17003533 0.95 ENSDART00000080545
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr2_+_41526904 0.94 ENSDART00000127520
activin A receptor, type 1 like
chr12_-_30359498 0.93 ENSDART00000152981
ENSDART00000189988
tudor domain containing 1
chr3_+_18807006 0.91 ENSDART00000180091
transportin 2 (importin 3, karyopherin beta 2b)
chr17_-_40956035 0.91 ENSDART00000124715
si:dkey-16j16.4
chr17_+_16046314 0.91 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr20_-_14114078 0.91 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr24_-_2450597 0.90 ENSDART00000188080
ENSDART00000093331
ras responsive element binding protein 1a
chr19_+_2631565 0.89 ENSDART00000171487
family with sequence similarity 126, member A
chr23_-_31913069 0.88 ENSDART00000135526
mitochondrial fission regulator 2
chr5_+_35786141 0.86 ENSDART00000022043
ENSDART00000127383
StAR-related lipid transfer (START) domain containing 8
chr5_+_37903790 0.85 ENSDART00000162470
transmembrane protease, serine 4b
chr8_+_49117518 0.85 ENSDART00000079631
RAD21 cohesin complex component like 1
chr7_+_34592526 0.84 ENSDART00000173959
formin homology 2 domain containing 1
chr20_-_37813863 0.84 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr16_-_17347727 0.79 ENSDART00000144392
zyxin
chr24_-_30862168 0.79 ENSDART00000168540
polypyrimidine tract binding protein 2a
chr11_+_35171406 0.78 ENSDART00000110839
MON1 secretory trafficking family member A
chr5_-_20491198 0.76 ENSDART00000183051
ENSDART00000144232
FIC domain containing
chr21_-_36453594 0.75 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8
chr16_+_47207691 0.75 ENSDART00000062507
islet cell autoantigen 1
chr19_+_15440841 0.74 ENSDART00000182329
lin-28 homolog A (C. elegans)
chr6_-_40922971 0.72 ENSDART00000155363
SFI1 centrin binding protein
chr5_+_6954162 0.69 ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr14_-_33945692 0.67 ENSDART00000168546
ENSDART00000189778
zinc finger, DHHC-type containing 24
chr19_+_40069524 0.65 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr19_-_30510259 0.62 ENSDART00000135128
ENSDART00000186169
ENSDART00000182974
ENSDART00000187797
BCL2 associated athanogene 6, like
chr3_+_26244353 0.62 ENSDART00000103733
ATPase family, AAA domain containing 5a
chr10_-_33297864 0.61 ENSDART00000163360
PR/SET domain 15
chr11_+_31864921 0.61 ENSDART00000180252
diaphanous-related formin 3
chr10_-_32494499 0.61 ENSDART00000129395
UV radiation resistance associated gene
chr2_-_57076687 0.60 ENSDART00000161523
solute carrier family 25, member 42
chr23_-_31913231 0.59 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr8_+_36500308 0.58 ENSDART00000098701
solute carrier family 7, member 4
chr9_-_746317 0.58 ENSDART00000129632
ENSDART00000130720
ubiquitin specific peptidase 37
chr3_-_30488063 0.56 ENSDART00000055393
ENSDART00000151367
mediator complex subunit 25
chr13_-_31017960 0.55 ENSDART00000145287
WDFY family member 4
chr15_-_2519640 0.54 ENSDART00000047013
signal recognition particle receptor, B subunit
chr10_-_32494304 0.54 ENSDART00000028161
UV radiation resistance associated gene
chr3_+_28860283 0.53 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr13_+_1132261 0.53 ENSDART00000146049
WD repeat domain 92
chr1_-_29139141 0.53 ENSDART00000075546
ENSDART00000133246
heat shock transcription factor 2 binding protein
chr1_-_45616470 0.53 ENSDART00000150165
activating transcription factor 7 interacting protein
chr18_+_19456648 0.53 ENSDART00000079695
zwilch kinetochore protein
chr16_+_6750756 0.52 ENSDART00000149720
zinc finger protein 236
chr21_-_25801956 0.52 ENSDART00000101219
methyltransferase like 27
chr23_-_25135046 0.51 ENSDART00000184844
ENSDART00000103989
isocitrate dehydrogenase 3 (NAD+) gamma
chr15_-_16177603 0.50 ENSDART00000156352
si:ch211-259g3.4
chr5_-_56412262 0.50 ENSDART00000083079
acetyl-CoA carboxylase alpha
chr8_+_11425048 0.50 ENSDART00000018739
tight junction protein 2b (zona occludens 2)
chr24_-_24724233 0.50 ENSDART00000127044
ENSDART00000012399
armadillo repeat containing 1
chr7_+_26649319 0.49 ENSDART00000173823
ENSDART00000101053
tumor protein p53 inducible protein 11a
chr6_+_21001264 0.49 ENSDART00000044519
ENSDART00000151278
connexin 44.2
chr3_-_26244256 0.48 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr7_-_71389375 0.48 ENSDART00000128928

chr2_+_20793982 0.47 ENSDART00000014785
proteoglycan 4a
chr11_-_35171162 0.46 ENSDART00000017393
TRAF-interacting protein
chr1_+_21937201 0.45 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr21_-_14174786 0.44 ENSDART00000145366
whirlin a
chr8_-_37249813 0.44 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
RNA binding motif protein 39b
chr5_+_4436405 0.43 ENSDART00000167969

chr15_-_43284021 0.43 ENSDART00000041677
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr18_-_43884044 0.42 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr15_+_1534644 0.42 ENSDART00000130413
structural maintenance of chromosomes 4
chr21_-_32060993 0.42 ENSDART00000131651
si:ch211-160j14.2
chr2_-_55298075 0.41 ENSDART00000186404
ENSDART00000149062
RAB8A, member RAS oncogene family
chr24_+_17068724 0.40 ENSDART00000191137
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr6_+_41191482 0.40 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr6_-_12172424 0.40 ENSDART00000109344
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr17_+_8799451 0.40 ENSDART00000189814
ENSDART00000191577
tonsoku-like, DNA repair protein
chr12_+_16087077 0.39 ENSDART00000141898
zinc finger protein 281b
chr2_-_57378748 0.38 ENSDART00000149235
transcription factor 3a
chr20_-_45060241 0.38 ENSDART00000185227
kelch-like family member 29
chr17_-_41798856 0.37 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr11_-_34522249 0.37 ENSDART00000158616
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr16_+_25126935 0.37 ENSDART00000058945
zgc:92590
chr16_+_28994709 0.37 ENSDART00000088023
gon-4-like (C. elegans)
chr25_-_27621268 0.35 ENSDART00000146205
ENSDART00000073511
hyaluronoglucosaminidase 6
chr17_-_31639845 0.35 ENSDART00000154196
zinc finger protein 839
chr15_-_4969525 0.33 ENSDART00000157223
lipoyl(octanoyl) transferase 2
chr14_+_44794936 0.33 ENSDART00000128881
zgc:195212
chr15_-_18115540 0.33 ENSDART00000131639
ENSDART00000047902
archain 1b
chr2_+_33326522 0.32 ENSDART00000056655
Kruppel-like factor 17
chr15_+_31344472 0.32 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
odorant receptor, family D, subfamily 107, member 1
chr19_-_19379084 0.32 ENSDART00000165206
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr8_+_50953776 0.31 ENSDART00000013870
zgc:56596
chr16_+_42471455 0.31 ENSDART00000166640
si:ch211-215k15.5
chr24_+_19415124 0.31 ENSDART00000186931
sulfatase 1
chr17_-_20118145 0.30 ENSDART00000149737
ENSDART00000165606
ryanodine receptor 2b (cardiac)
chr19_+_30884706 0.29 ENSDART00000052126
tyrosyl-tRNA synthetase
chr21_-_11654422 0.29 ENSDART00000081614
ENSDART00000132699
calpastatin
chr25_-_2723682 0.29 ENSDART00000113382
ADP-dependent glucokinase
chr1_-_26444075 0.29 ENSDART00000125690
integrator complex subunit 12
chr7_+_48667081 0.29 ENSDART00000083473
transient receptor potential cation channel, subfamily M, member 5
chr2_-_3403020 0.29 ENSDART00000092741
synaptosomal-associated protein, 47
chr8_+_2757821 0.28 ENSDART00000051403
ENSDART00000160551
SH3-domain GRB2-like endophilin B2a
chr7_+_23292133 0.28 ENSDART00000134489
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1
chr11_+_34523132 0.27 ENSDART00000192257
zinc finger, matrin-type 3
chr14_+_8940326 0.27 ENSDART00000159920
ribosomal protein S6 kinase a, like
chr6_+_3280939 0.27 ENSDART00000151359
lysine (K)-specific demethylase 4A, genome duplicate a
chr17_-_16422654 0.27 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr2_-_32384683 0.26 ENSDART00000182942
ENSDART00000141757
upstream binding transcription factor, like
chr8_-_25033681 0.26 ENSDART00000003493
nuclear transcription factor Y, alpha, like
chr1_+_18811679 0.25 ENSDART00000078610
solute carrier family 25, member 51a
chr22_-_14739491 0.25 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr11_+_12052791 0.24 ENSDART00000158479
si:ch211-156l18.8
chr5_+_36611128 0.24 ENSDART00000097684
neuro-oncological ventral antigen 1
chr5_-_37871526 0.24 ENSDART00000136450
Rho GTPase activating protein 35b
chr8_-_37249991 0.24 ENSDART00000189275
ENSDART00000178556
RNA binding motif protein 39b
chr6_-_3982783 0.23 ENSDART00000171944
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr11_+_33818179 0.23 ENSDART00000109418
speckle-type POZ protein-like b
chr3_-_16719244 0.23 ENSDART00000055859
polymerase (DNA directed), delta 1, catalytic subunit
chr8_-_16406440 0.22 ENSDART00000034004
Fas (TNFRSF6) associated factor 1
chr24_+_7336411 0.21 ENSDART00000191170
lysine (K)-specific methyltransferase 2Ca
chr13_+_22295905 0.21 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr21_-_25722834 0.20 ENSDART00000101208
abhydrolase domain containing 11
chr22_+_31207799 0.20 ENSDART00000133267
glutamate receptor interacting protein 2b
chr1_+_8694196 0.20 ENSDART00000025604
zgc:77849
chr25_+_11456696 0.20 ENSDART00000171408
si:ch73-141f14.1
chr3_-_31079186 0.19 ENSDART00000145636
ENSDART00000140569
elongin B
elongin B
chr14_-_22113600 0.17 ENSDART00000113752
si:dkey-6i22.5
chr20_-_45062514 0.17 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr20_-_7583486 0.16 ENSDART00000144729
ubiquitin specific peptidase 24
chr17_+_37227936 0.15 ENSDART00000076009
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
chr24_+_40860320 0.15 ENSDART00000161351
golgi reassembly stacking protein 1b
chr11_+_18873113 0.14 ENSDART00000103969
ENSDART00000103968
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr10_+_40660772 0.14 ENSDART00000148007
trace amine associated receptor 19l
chr16_-_16761164 0.14 ENSDART00000135872
si:dkey-27n14.1
chr21_+_5272059 0.13 ENSDART00000141981
lipoxygenase homology domains 1a
chr15_+_857148 0.12 ENSDART00000156949
si:dkey-7i4.13
chr19_-_5103141 0.11 ENSDART00000150952
triosephosphate isomerase 1a
chr4_+_2655358 0.10 ENSDART00000007638
B cell receptor associated protein 29
chr21_+_34088377 0.10 ENSDART00000170070
myotubularin related protein 1b
chr21_+_34088110 0.10 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
myotubularin related protein 1b
chr4_-_5455506 0.10 ENSDART00000156593
ENSDART00000154676
si:dkey-14d8.22
chr13_-_12602920 0.10 ENSDART00000102311
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr3_+_45364849 0.09 ENSDART00000153974
ubiquitin-conjugating enzyme E2Ia
chr4_+_9177997 0.09 ENSDART00000057254
ENSDART00000154614
nuclear transcription factor Y, beta a
chr3_+_45365098 0.09 ENSDART00000052746
ENSDART00000156555
ubiquitin-conjugating enzyme E2Ia
chr8_+_25034544 0.08 ENSDART00000123300
neugrin, neurite outgrowth associated
chr23_+_39695827 0.07 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr21_+_43404945 0.07 ENSDART00000142234
FERM domain containing 7
chr24_-_3783497 0.06 ENSDART00000158354
adenosine deaminase, RNA-specific, B2 (non-functional)
chr3_+_32365811 0.06 ENSDART00000155967
adaptor-related protein complex 2, alpha 1 subunit
chr13_+_2625150 0.05 ENSDART00000164177
phospholipid phosphatase 4
chr15_+_34988148 0.05 ENSDART00000076269
coiled-coil domain containing 105
chr8_+_23355484 0.05 ENSDART00000085361
ENSDART00000125729
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr20_-_5052786 0.05 ENSDART00000138818
ENSDART00000181655
ENSDART00000164274
AT rich interactive domain 1B (SWI1-like)
chr23_+_31912882 0.05 ENSDART00000140505
armadillo repeat containing 1, like
chr21_+_15592426 0.05 ENSDART00000138207
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr23_+_33963619 0.04 ENSDART00000140666
ENSDART00000084792
pyridoxal phosphate binding protein
chr24_+_32668675 0.04 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
chr8_+_37527575 0.04 ENSDART00000147239
odorant receptor, family H, subfamily 135, member 1
chr11_+_29770966 0.03 ENSDART00000088624
ENSDART00000124471
retinitis pigmentosa GTPase regulator b
chr13_+_25486608 0.02 ENSDART00000057689
BCL2 associated athanogene 3
chr12_+_48803098 0.01 ENSDART00000074768
peptidylprolyl isomerase Fb
chr16_+_33902006 0.00 ENSDART00000161807
ENSDART00000159474
guanine nucleotide binding protein-like 2 (nucleolar)

Network of associatons between targets according to the STRING database.

First level regulatory network of mixl1+mxtx1+sebox

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.8 4.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.5 1.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.4 1.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.4 1.4 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.3 4.2 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.2 1.0 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.2 0.9 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.2 0.9 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 2.8 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.9 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 1.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.5 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.3 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 0.4 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.9 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.9 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.3 GO:0051645 Golgi localization(GO:0051645)
0.1 1.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.5 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.5 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.6 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.3 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 1.5 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.3 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 3.4 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.6 GO:0060021 palate development(GO:0060021)
0.0 0.4 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.2 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.8 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.5 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 2.0 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.9 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.4 GO:0048634 regulation of muscle organ development(GO:0048634)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0097189 apoptotic body(GO:0097189)
0.5 1.4 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 6.8 GO:0043186 P granule(GO:0043186)
0.2 0.9 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.9 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.9 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 2.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 2.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 4.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0035060 brahma complex(GO:0035060)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0009374 biotin binding(GO:0009374)
0.3 1.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 0.6 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 2.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 2.8 GO:0032190 acrosin binding(GO:0032190)
0.1 2.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 1.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.9 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.1 0.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 2.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.3 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 4.6 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 6.0 GO:0042802 identical protein binding(GO:0042802)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.1 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 4.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 3.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation