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PRJNA195909:zebrafish embryo and larva development

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Results for mybl2b

Z-value: 1.93

Motif logo

Transcription factors associated with mybl2b

Gene Symbol Gene ID Gene Info
ENSDARG00000032264 v-myb avian myeloblastosis viral oncogene homolog-like 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mybl2bdr11_v1_chr11_+_1565806_15658060.881.8e-03Click!

Activity profile of mybl2b motif

Sorted Z-values of mybl2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_43656125 4.95 ENSDART00000136392
ENSDART00000192805
ENSDART00000181960
si:ch211-263m18.4
si:dkey-229d11.5
chr10_-_26202766 4.78 ENSDART00000136393
FH2 domain containing 3
chr2_+_6253246 4.46 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr2_+_307665 3.52 ENSDART00000082083
zgc:113452
chr19_+_43579786 2.72 ENSDART00000138404
si:ch211-199g17.2
chr8_-_1730686 2.54 ENSDART00000183802

chr25_-_16552135 2.44 ENSDART00000125836
si:ch211-266k8.4
chr1_-_354115 2.40 ENSDART00000141590
ENSDART00000098627
protein S
chr24_-_21150100 2.37 ENSDART00000154249
ENSDART00000193256
GRAM domain containing 1c
chr16_-_41714988 2.20 ENSDART00000138798
centrosomal protein 85
chr10_-_35257458 2.18 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr18_-_399554 2.14 ENSDART00000164374
ENSDART00000186311
ENSDART00000181816
ENSDART00000181892
si:ch211-79l17.1
chr19_-_46566430 2.14 ENSDART00000166668
exostosin glycosyltransferase 1b
chr10_-_45029041 2.14 ENSDART00000167878
polymerase (DNA directed), mu
chr9_+_18829360 2.07 ENSDART00000006514
general transcription factor IIF, polypeptide 2b
chr10_+_16501699 2.06 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr14_+_1365097 2.02 ENSDART00000083797
ENSDART00000176087
TBC1 domain family, member 9 (with GRAM domain)
chr9_+_22782027 1.95 ENSDART00000090816
replication timing regulatory factor 1
chr16_+_52343905 1.90 ENSDART00000131051
interferon lambda receptor 1
chr2_-_51507540 1.88 ENSDART00000166605
ENSDART00000161093
polymeric immunoglobulin receptor-like 2.3
chr13_+_45524475 1.85 ENSDART00000074567
ENSDART00000019113
macoilin 1b
chr9_-_2892045 1.81 ENSDART00000137201
cell division cycle associated 7a
chr8_+_26226044 1.78 ENSDART00000186503
WD repeat domain 6
chr6_+_2195625 1.78 ENSDART00000155659
activin A receptor type 1Bb
chr17_-_40879108 1.75 ENSDART00000010362
SPT7-like STAGA complex gamma subunit
chr16_+_25066880 1.72 ENSDART00000154084
im:7147486
chr16_+_42667560 1.71 ENSDART00000023452
dpy-19-like 1, like (H. sapiens)
chr3_+_1211242 1.66 ENSDART00000171287
ENSDART00000165769
polymerase (DNA-directed), delta interacting protein 3
chr4_-_837768 1.63 ENSDART00000185280
ENSDART00000135618
sine oculis binding protein homolog (Drosophila) b
chr4_-_72643171 1.61 ENSDART00000130126

chr9_-_29003245 1.58 ENSDART00000183391
ENSDART00000188836
protein tyrosine phosphatase, non-receptor type 4a
chr4_-_1684335 1.58 ENSDART00000019144
ENSDART00000113360
AT rich interactive domain 2 (ARID, RFX-like)
chr10_+_43406796 1.58 ENSDART00000184337
ENSDART00000183034
ENSDART00000180623
ENSDART00000132486
RAS p21 protein activator (GTPase activating protein) 1b
chr11_+_25583950 1.54 ENSDART00000111961
coiled-coil domain containing 120
chr20_+_13781779 1.54 ENSDART00000142999
ENSDART00000152471
lysophosphatidylglycerol acyltransferase 1
chr16_-_31342356 1.53 ENSDART00000136648
maestro heat-like repeat family member 1
chr8_+_23382568 1.53 ENSDART00000129167
microtubule-associated protein, RP/EB family, member 1a
chr5_+_59234421 1.51 ENSDART00000045518
PRKR interacting protein 1
chr2_+_38025260 1.49 ENSDART00000075905
heterogeneous nuclear ribonucleoprotein C
chr3_+_13929860 1.49 ENSDART00000164179
synaptonemal complex central element protein 2
chr9_-_2892250 1.44 ENSDART00000140695
cell division cycle associated 7a
chr24_-_25166416 1.43 ENSDART00000111552
ENSDART00000169495
pleckstrin homology-like domain, family B, member 2b
chr25_+_35134393 1.41 ENSDART00000185379

chr5_+_25084385 1.38 ENSDART00000134526
ENSDART00000111863
PAXX, non-homologous end joining factor
chr17_-_45378473 1.31 ENSDART00000132969
zinc finger protein 106a
chr7_+_5909271 1.31 ENSDART00000173363
zgc:165555
chr10_+_35257651 1.31 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr21_+_6212844 1.29 ENSDART00000150301
formin binding protein 1b
chr6_-_9563534 1.28 ENSDART00000184765
mitogen-activated protein kinase kinase kinase 2
chr7_+_1579236 1.27 ENSDART00000172830
SPT16 homolog, facilitates chromatin remodeling subunit
chr21_-_1635268 1.26 ENSDART00000151258
zgc:152948
chr24_-_41180149 1.24 ENSDART00000019975
activin A receptor type 2Ba
chr10_-_16868211 1.23 ENSDART00000171755
stomatin (EPB72)-like 2
chr3_-_9444749 1.22 ENSDART00000182191

chr24_-_25166720 1.22 ENSDART00000141601
pleckstrin homology-like domain, family B, member 2b
chr18_+_3579829 1.22 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
leucine-rich repeats and calponin homology (CH) domain containing 3
chr10_+_3145707 1.22 ENSDART00000160046
hypermethylated in cancer 2
chr4_-_2380173 1.21 ENSDART00000177727
nucleosome assembly protein 1-like 1
chr3_+_32080403 1.19 ENSDART00000124943
aldehyde dehydrogenase 16 family, member A1
chr17_-_31819837 1.19 ENSDART00000160281
abraxas 2b, BRISC complex subunit
chr12_+_4220353 1.19 ENSDART00000133675
mitogen-activated protein kinase 7
chr24_-_12832499 1.17 ENSDART00000182027
ENSDART00000039312
importin 4
chr22_+_10166407 1.17 ENSDART00000092104
PX domain containing serine/threonine kinase
chr4_-_5831036 1.17 ENSDART00000166232
forkhead box M1
chr20_+_42563618 1.15 ENSDART00000153441
insulin-like growth factor 2 receptor
chr4_-_26035770 1.14 ENSDART00000124514
ubiquitin specific peptidase 44
chr2_-_2451181 1.14 ENSDART00000101033
parathyroid hormone 1 receptor a
chr18_-_18587745 1.10 ENSDART00000191973
splicing factor 3b, subunit 3
chr19_+_4968947 1.09 ENSDART00000003634
ENSDART00000134808
StAR-related lipid transfer (START) domain containing 3
chr8_-_12432604 1.08 ENSDART00000133350
ENSDART00000140699
ENSDART00000101174
TNF receptor-associated factor 1
chr2_-_37632896 1.08 ENSDART00000008302
insulin receptor a
chr9_+_28140089 1.04 ENSDART00000046880
pleckstrin homology domain containing, family M, member 3
chr18_-_41160579 1.04 ENSDART00000181480

chr4_+_72205923 1.03 ENSDART00000181075
zgc:165515
chr3_-_33941319 1.00 ENSDART00000026090
ENSDART00000111878
general transcription factor IIF, polypeptide 1
chr5_+_6796291 0.99 ENSDART00000166868
ENSDART00000165308
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr13_+_15701849 0.97 ENSDART00000003517
tRNA methyltransferase 61A
chr2_-_193707 0.97 ENSDART00000187642
zinc finger protein 1014
chr19_+_16068445 0.96 ENSDART00000138709
glucocorticoid modulatory element binding protein 1
chr17_-_43012390 0.95 ENSDART00000155615
autophagy related 2B
chr2_-_1622641 0.95 ENSDART00000082143
protein kinase, cAMP-dependent, catalytic, beta b
chr2_-_22286828 0.95 ENSDART00000168653
family with sequence similarity 110, member B
chr7_-_17337233 0.94 ENSDART00000050236
ENSDART00000102141
novel immune-type receptor 8
chr7_-_6352569 0.93 ENSDART00000173074
zgc:165555
chr25_+_3099073 0.93 ENSDART00000022506
RAB3A interacting protein (rabin3)-like 1
chr6_+_3473657 0.90 ENSDART00000011785
RAD54 like
chr3_+_14641962 0.90 ENSDART00000091070
zgc:158403
chr12_-_7280551 0.90 ENSDART00000061633
zgc:171971
chr21_+_39432248 0.90 ENSDART00000179938
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr20_+_21595244 0.89 ENSDART00000010643
estrogen receptor 2a
chr10_+_42542517 0.89 ENSDART00000005496
potassium channel tetramerization domain containing 9b
chr17_-_11466700 0.88 ENSDART00000091159
ADP-dependent glucokinase 2
chr17_-_22573311 0.87 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exonuclease 1
chr22_+_24157807 0.87 ENSDART00000159165
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr3_-_33941875 0.87 ENSDART00000047660
general transcription factor IIF, polypeptide 1
chr8_+_23381892 0.86 ENSDART00000180950
ENSDART00000063010
ENSDART00000074241
ENSDART00000142783
microtubule-associated protein, RP/EB family, member 1a
chr1_+_23559478 0.85 ENSDART00000133659
non-SMC condensin I complex, subunit G
chr25_-_13403726 0.84 ENSDART00000056723
GINS complex subunit 3
chr11_-_20988238 0.84 ENSDART00000155238
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_-_61588998 0.83 ENSDART00000050912
peroxisomal biogenesis factor 12
chr21_+_34119759 0.82 ENSDART00000024750
ENSDART00000128242
high mobility group box 3b
chr2_+_10006839 0.82 ENSDART00000160304
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr25_+_34938317 0.81 ENSDART00000042678
vacuolar protein sorting 4a homolog A (S. cerevisiae)
chr22_+_1431743 0.80 ENSDART00000182871
Danio rerio si:dkeyp-53d3.6 (si:dkeyp-53d3.6), mRNA.
chr6_-_36795111 0.79 ENSDART00000160669
ENSDART00000104256
ENSDART00000187751
ENSDART00000161928
ENSDART00000183264
optic atrophy 1 (autosomal dominant)
chr25_-_37319117 0.79 ENSDART00000044499
immunoglobulin light 4 variable 9
chr19_-_47571456 0.77 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr2_+_10007113 0.77 ENSDART00000155213
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr25_-_3192405 0.76 ENSDART00000104835
Hermansky-Pudlak syndrome 5
chr1_-_23293261 0.76 ENSDART00000122648
UDP-glucose 6-dehydrogenase
chr2_-_9696283 0.75 ENSDART00000165712
selenoprotein T, 1a
chr23_+_36308717 0.75 ENSDART00000131711
heterogeneous nuclear ribonucleoprotein A1b
chr11_-_40519886 0.75 ENSDART00000172819
migration and invasion inhibitory protein
chr5_-_1869982 0.73 ENSDART00000055878
RNA terminal phosphate cyclase-like 1
chr20_+_53181017 0.71 ENSDART00000189692
ENSDART00000177109
FIG4 phosphoinositide 5-phosphatase
chr20_+_28266892 0.70 ENSDART00000103330
ChaC, cation transport regulator homolog 1 (E. coli)
chr11_+_5588122 0.67 ENSDART00000113281
zgc:172302
chr7_+_17106160 0.65 ENSDART00000190048
ENSDART00000180004
ENSDART00000013409
protein arginine methyltransferase 3
chr15_-_31508221 0.64 ENSDART00000121464
si:dkey-1m11.5
chr8_-_16675464 0.64 ENSDART00000191982
oxysterol binding protein-like 9
chr20_-_26047741 0.62 ENSDART00000141626
ENSDART00000112714
ENSDART00000152102
ENSDART00000078535
ENSDART00000151874
general transcription factor IIH, polypeptide 5
chr20_-_52271262 0.62 ENSDART00000135463
rhophilin, Rho GTPase binding protein 1
chr10_+_43037064 0.62 ENSDART00000160159
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr7_-_33130552 0.61 ENSDART00000127006
meiosis-specific nuclear structural 1
chr8_-_25761544 0.61 ENSDART00000078152
suppressor of variegation 3-9 homolog 1b
chr20_-_22798794 0.61 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr11_-_24015845 0.59 ENSDART00000191783
chitinase, acidic.3
chr12_+_34953038 0.58 ENSDART00000187022
ENSDART00000123988
ENSDART00000027034
QKI, KH domain containing, RNA binding 2
chr6_-_26080384 0.53 ENSDART00000157181
ENSDART00000154568
heparan sulfate 2-O-sulfotransferase 1b
chr15_+_17074185 0.53 ENSDART00000046648
cleft lip and palate associated transmembrane protein 1
chr7_-_24994722 0.53 ENSDART00000131671
REST corepressor 2
chr22_-_8006342 0.52 ENSDART00000162028
sc:d217
chr16_-_24708586 0.52 ENSDART00000178614

chr6_+_29693663 0.52 ENSDART00000150083
phosphodiesterase 6D, cGMP-specific, rod, delta
chr15_-_38218320 0.51 ENSDART00000152363
ras homolog family member Ga
chr7_+_19738665 0.49 ENSDART00000089333
triokinase/FMN cyclase
chr8_-_47206114 0.49 ENSDART00000147606
ENSDART00000060883
ENSDART00000060880
peptidylprolyl isomerase H (cyclophilin H)
chr8_+_47571211 0.49 ENSDART00000131460
phospholipase C, eta 2a
chr22_+_21153031 0.48 ENSDART00000166342
cytokine receptor-like factor 1b
chr14_-_4043818 0.48 ENSDART00000179870
sorting nexin 25
chr25_-_5815834 0.47 ENSDART00000112853
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr12_-_27242498 0.46 ENSDART00000152609
ENSDART00000152170
si:dkey-11c5.11
chr18_+_910992 0.46 ENSDART00000161206
ENSDART00000167229
pyruvate kinase M1/2a
chr9_+_14023942 0.46 ENSDART00000142749
si:ch211-67e16.4
chr22_+_28803739 0.45 ENSDART00000129476
ENSDART00000189726
tumor protein p53 binding protein, 2b
chr21_-_22681534 0.45 ENSDART00000159233
grass carp reovirus (GCRV)-induced gene 2f
chr1_+_30946231 0.45 ENSDART00000022841
methionyl aminopeptidase type 1D (mitochondrial)
chr20_-_52271015 0.45 ENSDART00000074307
rhophilin, Rho GTPase binding protein 1
chr21_+_37090795 0.45 ENSDART00000085786
zinc finger protein 346
chr22_+_21152847 0.44 ENSDART00000007321
cytokine receptor-like factor 1b
chr18_-_50676567 0.44 ENSDART00000172264
ubiquitin-conjugating enzyme E2Q family member 1
chr8_+_16676894 0.44 ENSDART00000076586
si:ch211-198n5.11
chr1_-_8020589 0.41 ENSDART00000143881
si:dkeyp-9d4.2
chr16_-_7214513 0.41 ENSDART00000150005
si:ch73-341k19.1
chr5_-_32882162 0.40 ENSDART00000085769
leucine rich repeat and sterile alpha motif containing 1
chr23_-_10722664 0.39 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
forkhead box P1a
chr6_+_29693492 0.38 ENSDART00000114172
phosphodiesterase 6D, cGMP-specific, rod, delta
chr5_+_42951852 0.38 ENSDART00000097615
MOB kinase activator 1Ba
chr5_-_61797220 0.37 ENSDART00000079855
im:7138535
chr8_-_47206399 0.37 ENSDART00000060877
peptidylprolyl isomerase H (cyclophilin H)
chr9_-_36924388 0.36 ENSDART00000059756
v-ral simian leukemia viral oncogene homolog Ba (ras related)
chr15_-_17074393 0.35 ENSDART00000155526
si:ch211-24o10.6
chr22_+_2801464 0.33 ENSDART00000132419
si:dkey-20i20.7
chr22_+_14117078 0.33 ENSDART00000013575
basic leucine zipper and W2 domains 1a
chr8_+_25629941 0.33 ENSDART00000186925
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a
chr12_+_19138452 0.33 ENSDART00000141346
ENSDART00000066397
PHD finger protein 5A
chr9_+_14023386 0.32 ENSDART00000140199
ENSDART00000124267
si:ch211-67e16.4
chr18_+_1145571 0.32 ENSDART00000135055
REC114 meiotic recombination protein
chr24_+_5912635 0.32 ENSDART00000153736
Pim proto-oncogene, serine/threonine kinase, related 63
chr2_+_25315591 0.32 ENSDART00000161386
fibronectin type III domain containing 3Ba
chr20_-_51267185 0.31 ENSDART00000158350
ENSDART00000023064
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr18_+_29898955 0.30 ENSDART00000064080
centromere protein N
chr22_+_2306386 0.30 ENSDART00000148300
ENSDART00000147644
si:dkey-4c15.16
chr17_+_1632294 0.30 ENSDART00000191959
signal recognition particle 14
chr10_+_6121558 0.30 ENSDART00000166799
ENSDART00000157947
talin 1
chr3_+_23248542 0.30 ENSDART00000185765
ENSDART00000192332
protein phosphatase 1, regulatory subunit 9Ba
chr7_-_24994568 0.29 ENSDART00000002961
REST corepressor 2
chr4_-_48578324 0.29 ENSDART00000122707
zinc finger protein 980
chr2_+_9970942 0.29 ENSDART00000153063
SEC22 homolog B, vesicle trafficking protein a
chr24_-_42108655 0.29 ENSDART00000032722
phosphatidylinositol glycan anchor biosynthesis, class M
chr24_+_24809877 0.27 ENSDART00000185117
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr9_+_37320222 0.27 ENSDART00000100622
solute carrier family 15 (oligopeptide transporter), member 2
chr12_-_26491464 0.26 ENSDART00000153361
si:dkey-287g12.6
chr6_-_33875919 0.24 ENSDART00000190411
transmembrane protein 69
chr10_-_26985231 0.22 ENSDART00000050585
zinc finger, HIT-type containing 2
chr22_-_23590069 0.19 ENSDART00000172067
coagulation factor XIII, B polypeptide
chr17_-_45383699 0.17 ENSDART00000141182
transmembrane protein 206
chr12_+_48803098 0.16 ENSDART00000074768
peptidylprolyl isomerase Fb
chr18_-_18821929 0.16 ENSDART00000178875
alanyl-tRNA synthetase
chr4_+_308697 0.15 ENSDART00000174021
ENSDART00000131419
ENSDART00000067489
si:ch211-51e12.7
chr18_-_26797723 0.14 ENSDART00000008013
SEC11 homolog A, signal peptidase complex subunit
chr20_-_46817223 0.14 ENSDART00000100336
estrogen-related receptor gamma b
chr4_-_54100377 0.11 ENSDART00000188064
si:dkey-199m13.7
chr9_-_28275600 0.11 ENSDART00000170094
cAMP responsive element binding protein 1b
chr19_+_31904836 0.10 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tumor protein D52
chr17_-_35352690 0.09 ENSDART00000016053
ring finger protein 144aa
chr24_-_36337395 0.08 ENSDART00000154402
si:ch211-40k21.9
chr15_+_5277761 0.08 ENSDART00000153954
si:ch1073-166e24.4
chr20_-_35052464 0.08 ENSDART00000037195
kinesin family member 26Bb
chr23_+_20689255 0.07 ENSDART00000182420
ubiquitin specific peptidase 21

Network of associatons between targets according to the STRING database.

First level regulatory network of mybl2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0042730 fibrinolysis(GO:0042730)
0.6 1.7 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 1.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.4 1.5 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.4 1.9 GO:0023041 neuronal signal transduction(GO:0023041)
0.3 1.3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.3 1.1 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 2.4 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.3 4.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.1 3.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 3.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.5 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.8 GO:0048069 eye pigmentation(GO:0048069)
0.1 0.8 GO:0003188 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.1 1.0 GO:1902534 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.1 1.6 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 1.0 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.7 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 2.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.9 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.9 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 1.2 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 3.2 GO:0048538 thymus development(GO:0048538)
0.1 1.5 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 0.5 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 2.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 3.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.6 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.7 GO:0033700 phospholipid efflux(GO:0033700)
0.1 0.9 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 2.2 GO:0007050 cell cycle arrest(GO:0007050)
0.1 1.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 1.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.9 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 3.0 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 0.7 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 1.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.6 GO:0006032 chitin catabolic process(GO:0006032)
0.1 1.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.9 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 2.1 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.8 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.5 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 2.2 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 1.5 GO:0001878 response to yeast(GO:0001878)
0.0 1.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.7 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 4.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.9 GO:0006298 mismatch repair(GO:0006298)
0.0 1.9 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.1 GO:0030301 cholesterol transport(GO:0030301)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.4 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 1.2 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0032475 otolith formation(GO:0032475)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.2 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 1.9 GO:0048884 neuromast development(GO:0048884)
0.0 0.6 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 3.0 GO:0006869 lipid transport(GO:0006869)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.9 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.5 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.3 0.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 0.8 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.3 1.8 GO:0030914 STAGA complex(GO:0030914)
0.2 1.5 GO:0000801 central element(GO:0000801)
0.2 0.9 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.2 0.9 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.2 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.2 3.0 GO:0048179 activin receptor complex(GO:0048179)
0.2 1.0 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.2 1.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 0.8 GO:0000811 GINS complex(GO:0000811)
0.1 1.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 1.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 2.7 GO:0045180 basal cortex(GO:0045180)
0.1 1.3 GO:0035101 FACT complex(GO:0035101)
0.1 0.9 GO:0000796 condensin complex(GO:0000796)
0.1 2.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.6 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.3 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.9 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.8 GO:0031082 BLOC complex(GO:0031082)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 2.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 2.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.5 1.9 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.4 4.5 GO:0035804 structural constituent of egg coat(GO:0035804)
0.3 1.8 GO:0016361 activin receptor activity, type I(GO:0016361)
0.3 2.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 0.9 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.3 0.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.3 0.8 GO:1901612 cardiolipin binding(GO:1901612)
0.2 1.0 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 1.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 1.1 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 0.6 GO:0019777 Atg12 transferase activity(GO:0019777)
0.2 1.0 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.2 0.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 0.8 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.2 0.5 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.2 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.9 GO:1903924 estradiol binding(GO:1903924)
0.1 0.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.7 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 1.0 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 0.8 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 3.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.2 GO:0005537 mannose binding(GO:0005537)
0.1 0.8 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 2.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 1.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.5 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 0.6 GO:0004568 chitinase activity(GO:0004568)
0.1 0.8 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 6.7 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.3 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.7 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.7 GO:0032934 sterol binding(GO:0032934)
0.0 1.2 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 1.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 2.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 2.2 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.8 PID MYC PATHWAY C-MYC pathway
0.0 1.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 2.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)